TMSB4XP4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.63573429
2neuron fate determination (GO:0048664)8.45039585
3viral transcription (GO:0019083)8.30149529
4translational termination (GO:0006415)7.94166300
5energy coupled proton transport, down electrochemical gradient (GO:0015985)7.36992284
6ATP synthesis coupled proton transport (GO:0015986)7.36992284
7cotranslational protein targeting to membrane (GO:0006613)6.80910723
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.79220068
9protein targeting to ER (GO:0045047)6.67664509
10ribosomal small subunit assembly (GO:0000028)6.64808576
11translational elongation (GO:0006414)6.38921495
12establishment of protein localization to endoplasmic reticulum (GO:0072599)6.38266161
13* sequestering of actin monomers (GO:0042989)6.33878666
14cellular protein complex disassembly (GO:0043624)6.15111695
15protein localization to endoplasmic reticulum (GO:0070972)6.14881608
16viral life cycle (GO:0019058)5.88445041
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.74788100
18behavioral response to nicotine (GO:0035095)5.54311486
19respiratory electron transport chain (GO:0022904)5.31184864
20maturation of SSU-rRNA (GO:0030490)5.27298634
21electron transport chain (GO:0022900)5.23822636
22protein complex disassembly (GO:0043241)5.23775135
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.22595717
24translational initiation (GO:0006413)5.20497543
25lateral sprouting from an epithelium (GO:0060601)5.02216039
26ribosomal small subunit biogenesis (GO:0042274)4.89620624
27macromolecular complex disassembly (GO:0032984)4.89610463
28establishment of protein localization to mitochondrial membrane (GO:0090151)4.84564247
29serotonin receptor signaling pathway (GO:0007210)4.78965878
30epithelial cilium movement (GO:0003351)4.70772771
31midbrain development (GO:0030901)4.59299318
32inner mitochondrial membrane organization (GO:0007007)4.49663214
33protein targeting to membrane (GO:0006612)4.47385388
34protein neddylation (GO:0045116)4.46463563
35epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.40731871
36limb bud formation (GO:0060174)4.27030839
37otic vesicle formation (GO:0030916)4.14161072
38intraciliary transport (GO:0042073)3.96754533
39cranial suture morphogenesis (GO:0060363)3.96523858
40ATP biosynthetic process (GO:0006754)3.89834634
41cilium movement (GO:0003341)3.87251148
42nuclear-transcribed mRNA catabolic process (GO:0000956)3.76581885
43neuron fate specification (GO:0048665)3.73503388
44chaperone-mediated protein transport (GO:0072321)3.69637886
45hydrogen ion transmembrane transport (GO:1902600)3.68936535
46prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060523.65657725
47mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.62957183
48mitochondrial respiratory chain complex I assembly (GO:0032981)3.62957183
49NADH dehydrogenase complex assembly (GO:0010257)3.62957183
50ribosomal large subunit biogenesis (GO:0042273)3.60519516
51mRNA catabolic process (GO:0006402)3.58369583
52protein complex biogenesis (GO:0070271)3.55772408
53purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.51396579
54purine nucleoside triphosphate biosynthetic process (GO:0009145)3.48088104
55presynaptic membrane assembly (GO:0097105)3.41104982
56axonemal dynein complex assembly (GO:0070286)3.39826013
57spinal cord association neuron differentiation (GO:0021527)3.38137402
58tongue development (GO:0043586)3.28862523
59proton transport (GO:0015992)3.27425110
60positive regulation of gastrulation (GO:2000543)3.25819617
61translation (GO:0006412)3.22967014
62mitochondrial respiratory chain complex assembly (GO:0033108)3.21903530
63hydrogen transport (GO:0006818)3.20581319
64neuronal stem cell maintenance (GO:0097150)3.14817454
65presynaptic membrane organization (GO:0097090)3.12573704
66RNA catabolic process (GO:0006401)3.11388899
67establishment of protein localization to membrane (GO:0090150)3.04387249
68ribonucleoside triphosphate biosynthetic process (GO:0009201)2.98231978
69retinal ganglion cell axon guidance (GO:0031290)2.94622950
70postsynaptic membrane organization (GO:0001941)2.91821735
71nonmotile primary cilium assembly (GO:0035058)2.91318557
72regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.91258674
73regulation of phospholipid biosynthetic process (GO:0071071)2.90189981
74kidney morphogenesis (GO:0060993)2.90158977
75craniofacial suture morphogenesis (GO:0097094)2.86665110
76spermatid nucleus differentiation (GO:0007289)2.83519739
77G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.83283743
78mesenchymal cell proliferation (GO:0010463)2.81637112
79embryonic digestive tract morphogenesis (GO:0048557)2.80381388
80cGMP biosynthetic process (GO:0006182)2.79419170
81somite development (GO:0061053)2.75120218
82neural tube formation (GO:0001841)2.71429876
83negative regulation of axon guidance (GO:1902668)2.69811464
84positive regulation of embryonic development (GO:0040019)2.64814227
85protein targeting (GO:0006605)2.64757111
86regulation of non-canonical Wnt signaling pathway (GO:2000050)2.62908134
87hematopoietic stem cell proliferation (GO:0071425)2.61393782
88establishment of protein localization to organelle (GO:0072594)2.60615970
89radial glial cell differentiation (GO:0060019)2.60384214
90nucleoside triphosphate biosynthetic process (GO:0009142)2.59243077
91neuron projection extension involved in neuron projection guidance (GO:1902284)2.58366869
92axon extension involved in axon guidance (GO:0048846)2.58366869
93negative regulation of translation, ncRNA-mediated (GO:0040033)2.52133670
94regulation of translation, ncRNA-mediated (GO:0045974)2.52133670
95negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.52133670
96regulation of timing of cell differentiation (GO:0048505)2.52016872
97regulation of appetite (GO:0032098)2.51210213
98protein localization to membrane (GO:0072657)2.50192740
99lung lobe morphogenesis (GO:0060463)2.48817957
100digestive tract morphogenesis (GO:0048546)2.48141453

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.36342712
2CBX2_27304074_Chip-Seq_ESCs_Mouse3.24773165
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.08133199
4VDR_22108803_ChIP-Seq_LS180_Human3.04520644
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.89596415
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.71048804
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.70196292
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.69391185
9BMI1_23680149_ChIP-Seq_NPCS_Mouse2.43523286
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.43474199
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.29317119
12FUS_26573619_Chip-Seq_HEK293_Human2.28916993
13TAF15_26573619_Chip-Seq_HEK293_Human2.25007918
14JARID2_20064375_ChIP-Seq_MESCs_Mouse2.21662957
15RNF2_27304074_Chip-Seq_NSC_Mouse2.20440927
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.19460730
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.15057105
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.07292653
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.05882592
20FOXM1_23109430_ChIP-Seq_U2OS_Human2.00973813
21SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.00313298
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.99789768
23NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.96244902
24CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.94913860
25PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.94330836
26POU5F1_16153702_ChIP-ChIP_HESCs_Human1.94020154
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.91345383
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.88508832
29EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87081222
30RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87081222
31RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.84130251
32JARID2_20075857_ChIP-Seq_MESCs_Mouse1.78058022
33ZFP57_27257070_Chip-Seq_ESCs_Mouse1.76524386
34EWS_26573619_Chip-Seq_HEK293_Human1.72348508
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.71084899
36KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.68723551
37SOX2_16153702_ChIP-ChIP_HESCs_Human1.66742634
38TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.63783366
39SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.63325464
40SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.63130606
41POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.62852418
42TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62852418
43P300_19829295_ChIP-Seq_ESCs_Human1.61478574
44ZNF274_21170338_ChIP-Seq_K562_Hela1.56682007
45SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.52272268
46RNF2_27304074_Chip-Seq_ESCs_Mouse1.52231682
47CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.47269461
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47115484
49TP53_20018659_ChIP-ChIP_R1E_Mouse1.44496535
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43876616
51TTF2_22483619_ChIP-Seq_HELA_Human1.42756024
52ELK1_19687146_ChIP-ChIP_HELA_Human1.41345648
53EZH2_27294783_Chip-Seq_ESCs_Mouse1.38561575
54SUZ12_27294783_Chip-Seq_ESCs_Mouse1.37403683
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.36914510
56CREB1_15753290_ChIP-ChIP_HEK293T_Human1.32042311
57CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.31802346
58RBPJ_22232070_ChIP-Seq_NCS_Mouse1.30722202
59REST_21632747_ChIP-Seq_MESCs_Mouse1.29108422
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28429862
61MYC_18940864_ChIP-ChIP_HL60_Human1.26765230
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.25763264
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25098562
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.24056395
65MYC_18555785_ChIP-Seq_MESCs_Mouse1.20049214
66ETS1_20019798_ChIP-Seq_JURKAT_Human1.17806271
67GATA1_26923725_Chip-Seq_HPCs_Mouse1.17544208
68GBX2_23144817_ChIP-Seq_PC3_Human1.14332067
69KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.13735675
70RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13475702
71ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.13474759
72TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10434202
73NANOG_16153702_ChIP-ChIP_HESCs_Human1.08872707
74LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08642744
75XRN2_22483619_ChIP-Seq_HELA_Human1.08354042
76ELK1_22589737_ChIP-Seq_MCF10A_Human1.08188937
77FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.04825955
78TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.04473830
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.04458448
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04133591
81YY1_21170310_ChIP-Seq_MESCs_Mouse1.03131872
82BCAT_22108803_ChIP-Seq_LS180_Human1.02899900
83PIAS1_25552417_ChIP-Seq_VCAP_Human1.01779668
84ETV2_25802403_ChIP-Seq_MESCs_Mouse0.96456246
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94765949
86SMAD4_21799915_ChIP-Seq_A2780_Human0.94555805
87SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94440812
88AR_25329375_ChIP-Seq_VCAP_Human0.94005744
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.93413643
90MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93399336
91CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.93392523
92KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.93059612
93KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.93059612
94KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.93059612
95ER_23166858_ChIP-Seq_MCF-7_Human0.91685232
96RING1B_27294783_Chip-Seq_ESCs_Mouse0.91102664
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90152737
98SOX9_26525672_Chip-Seq_HEART_Mouse0.89870197
99TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.89662038
100NANOG_19829295_ChIP-Seq_ESCs_Human0.89333387

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis6.79917190
2MP0010030_abnormal_orbit_morphology5.89298376
3MP0009379_abnormal_foot_pigmentation4.88786982
4MP0003136_yellow_coat_color3.51412875
5MP0002938_white_spotting2.82878721
6MP0000372_irregular_coat_pigmentation2.67506001
7MP0001346_abnormal_lacrimal_gland2.58447114
8MP0002638_abnormal_pupillary_reflex2.47698533
9MP0000579_abnormal_nail_morphology2.38108221
10MP0003880_abnormal_central_pattern2.32441492
11MP0006292_abnormal_olfactory_placode2.26955718
12MP0003938_abnormal_ear_development2.14281031
13MP0008789_abnormal_olfactory_epithelium2.12258869
14MP0004142_abnormal_muscle_tone2.04713570
15MP0005171_absent_coat_pigmentation2.03740086
16MP0001529_abnormal_vocalization1.93438991
17MP0003283_abnormal_digestive_organ1.89108322
18MP0005423_abnormal_somatic_nervous1.88818264
19MP0000537_abnormal_urethra_morphology1.86655121
20MP0005499_abnormal_olfactory_system1.85273593
21MP0005394_taste/olfaction_phenotype1.85273593
22MP0002653_abnormal_ependyma_morphology1.77619871
23MP0000631_abnormal_neuroendocrine_gland1.72778266
24MP0006276_abnormal_autonomic_nervous1.68622746
25MP0003011_delayed_dark_adaptation1.65851008
26MP0002234_abnormal_pharynx_morphology1.64165709
27MP0000778_abnormal_nervous_system1.61514006
28MP0010386_abnormal_urinary_bladder1.57880054
29MP0004133_heterotaxia1.57501496
30MP0008995_early_reproductive_senescence1.55976069
31MP0008961_abnormal_basal_metabolism1.52673096
32MP0005084_abnormal_gallbladder_morpholo1.51893524
33MP0000026_abnormal_inner_ear1.51014835
34MP0001984_abnormal_olfaction1.46277261
35MP0006072_abnormal_retinal_apoptosis1.46132790
36MP0002282_abnormal_trachea_morphology1.44174537
37MP0002249_abnormal_larynx_morphology1.43922818
38MP0005248_abnormal_Harderian_gland1.40387861
39MP0003937_abnormal_limbs/digits/tail_de1.38680488
40MP0002233_abnormal_nose_morphology1.33466127
41MP0002697_abnormal_eye_size1.33004279
42MP0002736_abnormal_nociception_after1.32122548
43MP0001293_anophthalmia1.30452452
44MP0003122_maternal_imprinting1.24480885
45MP0001286_abnormal_eye_development1.24464474
46MP0000049_abnormal_middle_ear1.23521110
47MP0009250_abnormal_appendicular_skeleto1.16003851
48MP0005197_abnormal_uvea_morphology1.15747144
49MP0002822_catalepsy1.13074104
50MP0000462_abnormal_digestive_system1.05730463
51MP0002928_abnormal_bile_duct1.04905310
52MP0005187_abnormal_penis_morphology1.02981566
53MP0002295_abnormal_pulmonary_circulatio1.00885312
54MP0004742_abnormal_vestibular_system0.99526974
55MP0001440_abnormal_grooming_behavior0.96986186
56MP0002734_abnormal_mechanical_nocicepti0.96566590
57MP0005253_abnormal_eye_physiology0.96456332
58MP0001324_abnormal_eye_pigmentation0.95768979
59MP0001968_abnormal_touch/_nociception0.95449141
60MP0001486_abnormal_startle_reflex0.94792559
61MP0005551_abnormal_eye_electrophysiolog0.92863711
62MP0000647_abnormal_sebaceous_gland0.90865011
63MP0002752_abnormal_somatic_nervous0.89410928
64MP0002184_abnormal_innervation0.88894522
65MP0003755_abnormal_palate_morphology0.88689780
66MP0009745_abnormal_behavioral_response0.86970827
67MP0003861_abnormal_nervous_system0.85246923
68MP0002102_abnormal_ear_morphology0.84850499
69MP0005195_abnormal_posterior_eye0.82917890
70MP0001485_abnormal_pinna_reflex0.82432907
71MP0005391_vision/eye_phenotype0.81230115
72MP0005408_hypopigmentation0.80977657
73MP0002272_abnormal_nervous_system0.80696366
74MP0002572_abnormal_emotion/affect_behav0.78977164
75MP0003942_abnormal_urinary_system0.78403257
76MP0002064_seizures0.76317524
77MP0000762_abnormal_tongue_morphology0.76303116
78MP0001299_abnormal_eye_distance/0.75302949
79MP0003315_abnormal_perineum_morphology0.71791120
80MP0003121_genomic_imprinting0.71164492
81MP0009053_abnormal_anal_canal0.70824618
82MP0000955_abnormal_spinal_cord0.70651614
83MP0002557_abnormal_social/conspecific_i0.69595268
84MP0002882_abnormal_neuron_morphology0.67939671
85MP0005646_abnormal_pituitary_gland0.67831767
86MP0002932_abnormal_joint_morphology0.67522086
87MP0002751_abnormal_autonomic_nervous0.66610926
88MP0000383_abnormal_hair_follicle0.66431109
89MP0003959_abnormal_lean_body0.65549480
90MP0004885_abnormal_endolymph0.64881014
91MP0002095_abnormal_skin_pigmentation0.64430585
92MP0003385_abnormal_body_wall0.62556830
93MP0002152_abnormal_brain_morphology0.62472637
94MP0001963_abnormal_hearing_physiology0.62108336
95MP0002116_abnormal_craniofacial_bone0.61899836
96MP0002277_abnormal_respiratory_mucosa0.61202288
97MP0001879_abnormal_lymphatic_vessel0.60934358
98MP0005645_abnormal_hypothalamus_physiol0.59795094
99MP0003119_abnormal_digestive_system0.58849125
100MP0003638_abnormal_response/metabolism_0.58725703

Predicted human phenotypes

RankGene SetZ-score
1Abnormal number of erythroid precursors (HP:0012131)4.75115590
2Abnormality of cells of the erythroid lineage (HP:0012130)4.60841395
3Increased hepatocellular lipid droplets (HP:0006565)4.59201836
4Congenital, generalized hypertrichosis (HP:0004540)4.23233298
5Concave nail (HP:0001598)3.96682358
6Partial duplication of thumb phalanx (HP:0009944)3.96286545
7Abnormality of the phalanges of the 2nd finger (HP:0009541)3.94435567
8Lipid accumulation in hepatocytes (HP:0006561)3.92667352
9Abnormal ciliary motility (HP:0012262)3.77763309
10Macrocytic anemia (HP:0001972)3.69228939
11Partial duplication of the phalanx of hand (HP:0009999)3.66989911
12Reticulocytopenia (HP:0001896)3.66125318
13Abnormal respiratory motile cilium physiology (HP:0012261)3.65696555
14Renal Fanconi syndrome (HP:0001994)3.65051811
15Mitochondrial inheritance (HP:0001427)3.60891123
16Esophageal atresia (HP:0002032)3.56794722
17Abnormal respiratory motile cilium morphology (HP:0005938)3.51296549
18Abnormal respiratory epithelium morphology (HP:0012253)3.51296549
19Stenosis of the external auditory canal (HP:0000402)3.28913512
20Abnormality of the labia minora (HP:0012880)3.23709784
21Acute necrotizing encephalopathy (HP:0006965)3.20405175
22Split foot (HP:0001839)3.19854646
23Rhinitis (HP:0012384)3.18930479
24Hepatocellular necrosis (HP:0001404)3.11978853
25Abnormality of the parietal bone (HP:0002696)3.11131147
26Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.93731434
27Rib fusion (HP:0000902)2.93530045
28Septo-optic dysplasia (HP:0100842)2.92998878
29Exertional dyspnea (HP:0002875)2.91110523
30Abnormality of the middle phalanges of the toes (HP:0010183)2.88576876
31Focal motor seizures (HP:0011153)2.88032712
32Hepatic necrosis (HP:0002605)2.82831057
33Increased CSF lactate (HP:0002490)2.77978443
34Absent septum pellucidum (HP:0001331)2.73703727
35Synostosis involving the elbow (HP:0003938)2.71484869
36Humeroradial synostosis (HP:0003041)2.71484869
37Chronic otitis media (HP:0000389)2.71217062
38Abnormal mitochondria in muscle tissue (HP:0008316)2.64005257
393-Methylglutaconic aciduria (HP:0003535)2.63855934
40Respiratory difficulties (HP:0002880)2.62712751
41Broad metatarsal (HP:0001783)2.61034754
42Acute encephalopathy (HP:0006846)2.60142644
43Progressive macrocephaly (HP:0004481)2.52978245
44Pallor (HP:0000980)2.49192908
45Absent/shortened dynein arms (HP:0200106)2.46103475
46Dynein arm defect of respiratory motile cilia (HP:0012255)2.46103475
47Chronic sinusitis (HP:0011109)2.44729108
48Myokymia (HP:0002411)2.43284198
49Sleep apnea (HP:0010535)2.39736823
50Gastrointestinal atresia (HP:0002589)2.39565889
51Abnormality of renal resorption (HP:0011038)2.38347071
52Abnormality of the 2nd finger (HP:0004100)2.36461539
53Pancreatic fibrosis (HP:0100732)2.33809462
54Increased intramyocellular lipid droplets (HP:0012240)2.30253037
55Genital tract atresia (HP:0001827)2.28441718
56Nephronophthisis (HP:0000090)2.27204188
57Vaginal atresia (HP:0000148)2.24695518
58Nasolacrimal duct obstruction (HP:0000579)2.21091584
59Coronal craniosynostosis (HP:0004440)2.20790126
60Hypoplasia of the pons (HP:0012110)2.17688121
61Glycosuria (HP:0003076)2.12302519
62Abnormality of urine glucose concentration (HP:0011016)2.12302519
63Abnormality of the septum pellucidum (HP:0007375)2.11026088
64Molar tooth sign on MRI (HP:0002419)2.09063287
65Abnormality of midbrain morphology (HP:0002418)2.09063287
66Aplasia involving bones of the upper limbs (HP:0009823)2.07544744
67Aplasia of the phalanges of the hand (HP:0009802)2.07544744
68Aplasia involving bones of the extremities (HP:0009825)2.07544744
69Pancreatic cysts (HP:0001737)2.05770218
70Hyperphosphaturia (HP:0003109)2.05040757
71Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.04700570
72Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.02989583
73Stomach cancer (HP:0012126)2.01528119
74Cutaneous finger syndactyly (HP:0010554)2.01240414
75Symphalangism affecting the phalanges of the hand (HP:0009773)2.00820912
76Trigonocephaly (HP:0000243)2.00602834
77Duplication of thumb phalanx (HP:0009942)2.00419901
78Broad distal phalanx of finger (HP:0009836)1.99491436
79Short hallux (HP:0010109)1.98029234
80Medial flaring of the eyebrow (HP:0010747)1.97708986
81Abnormality of the lacrimal duct (HP:0011481)1.96791492
82Taurodontia (HP:0000679)1.96153891
83Abnormality of permanent molar morphology (HP:0011071)1.96153891
84Abnormality of the dental root (HP:0006486)1.96153891
85Optic disc pallor (HP:0000543)1.95854452
86Oligodactyly (hands) (HP:0001180)1.92448855
87Abnormality of the pons (HP:0007361)1.91697005
88True hermaphroditism (HP:0010459)1.90958069
89Hypoplasia of the ulna (HP:0003022)1.90491657
90Aplasia/Hypoplasia of the hallux (HP:0008362)1.87129161
91Abnormality of the renal medulla (HP:0100957)1.86518261
92Oligodactyly (HP:0012165)1.85202563
93Recurrent corneal erosions (HP:0000495)1.84097769
94Woolly hair (HP:0002224)1.83606060
95Abnormality of the nasolacrimal system (HP:0000614)1.81405136
96Polyphagia (HP:0002591)1.81201658
97Depressed nasal ridge (HP:0000457)1.80347059
98Abnormality of incisor morphology (HP:0011063)1.80015116
99Turricephaly (HP:0000262)1.79401143
100Short nail (HP:0001799)1.79233285

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FGFR25.28754838
2TLK14.53093635
3PNCK3.39492703
4VRK23.19585724
5TNIK2.96923353
6PASK2.94564677
7CASK2.94401149
8MAP3K42.88707007
9WNK32.48706313
10MARK12.40949509
11MAPK152.24106085
12NME12.07219479
13EPHB21.97645987
14EPHA31.95380229
15MAP2K71.89109488
16DYRK21.85088416
17DYRK31.78375700
18INSRR1.76154097
19ZAK1.76011885
20NUAK11.73854807
21WEE11.68546455
22VRK11.67106322
23MAP2K41.59130956
24BUB11.50813997
25TGFBR11.43887735
26CAMK1G1.38908599
27CDK81.33268471
28LRRK21.29749424
29PAK31.29504399
30GRK71.27738789
31ADRBK21.19082543
32STK38L1.18427684
33MAP3K121.15146603
34CCNB11.11553037
35UHMK11.10403045
36NTRK21.09819799
37TAF11.09759455
38FGFR11.01124303
39STK240.94526643
40SRPK10.92737819
41PRKCG0.86086129
42GRK10.84746847
43MAP4K20.80368393
44ADRBK10.78383949
45EPHA40.77184898
46SGK2230.74010349
47SGK4940.74010349
48BMPR1B0.73435535
49PINK10.70754269
50STK160.69986907
51PLK40.67183832
52AKT30.65993549
53MINK10.64293339
54MAPK130.63218516
55CAMK10.62752295
56AURKB0.62489597
57MUSK0.61636929
58PRKG10.59295106
59OBSCN0.56925389
60DDR20.54967498
61MAP3K100.54917414
62PLK30.54538707
63MKNK10.53905223
64MAP3K90.53641372
65CDK30.53259565
66NEK20.50826858
67STK30.50707382
68RPS6KA40.50132266
69NTRK30.49342869
70SGK20.49244079
71DYRK1A0.45554588
72PRKACA0.45343903
73TAOK30.39667095
74NLK0.38244813
75CSNK2A10.35604142
76MAP3K60.35055817
77AURKA0.34552373
78WNK40.33045425
79DYRK1B0.32539151
80SIK20.31674307
81STK110.30761210
82RPS6KA50.30715374
83CDK190.29645175
84CSNK2A20.28721430
85MAP3K110.28599027
86TYRO30.28455769
87PRKCE0.27868836
88CHUK0.27565273
89TIE10.27323147
90PRKACB0.26966857
91CAMK1D0.26427639
92PHKG10.26214450
93PHKG20.26214450
94BCKDK0.25318456
95DAPK30.24125970
96IRAK20.23949016
97CAMK2A0.23362977
98OXSR10.22239975
99CSNK1E0.20680172
100CHEK20.20671712

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.33131928
2Oxidative phosphorylation_Homo sapiens_hsa001906.06996484
3Parkinsons disease_Homo sapiens_hsa050125.02925903
4Alzheimers disease_Homo sapiens_hsa050103.77031245
5Huntingtons disease_Homo sapiens_hsa050163.73538173
6Cardiac muscle contraction_Homo sapiens_hsa042603.40693850
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.29800096
8Proteasome_Homo sapiens_hsa030502.76507329
9Basal cell carcinoma_Homo sapiens_hsa052172.69179633
10Protein export_Homo sapiens_hsa030602.57461309
11Hedgehog signaling pathway_Homo sapiens_hsa043402.00016371
12Nicotine addiction_Homo sapiens_hsa050331.90929972
13RNA polymerase_Homo sapiens_hsa030201.77210736
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.50816334
15Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.25529153
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.23243402
17Taste transduction_Homo sapiens_hsa047421.14917528
18Collecting duct acid secretion_Homo sapiens_hsa049661.09635887
19Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.03424971
20Phototransduction_Homo sapiens_hsa047441.02061984
21Serotonergic synapse_Homo sapiens_hsa047260.99250986
22Wnt signaling pathway_Homo sapiens_hsa043100.97111707
23Homologous recombination_Homo sapiens_hsa034400.96355664
24Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.94854999
25Melanogenesis_Homo sapiens_hsa049160.93331367
26Nitrogen metabolism_Homo sapiens_hsa009100.93173169
27Spliceosome_Homo sapiens_hsa030400.89426499
28Cocaine addiction_Homo sapiens_hsa050300.87578690
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86284444
30Folate biosynthesis_Homo sapiens_hsa007900.83668840
31Butanoate metabolism_Homo sapiens_hsa006500.81817291
32Hippo signaling pathway_Homo sapiens_hsa043900.78412116
33Steroid hormone biosynthesis_Homo sapiens_hsa001400.77694995
34RNA degradation_Homo sapiens_hsa030180.77439797
35Gap junction_Homo sapiens_hsa045400.77318023
36TGF-beta signaling pathway_Homo sapiens_hsa043500.76484273
37Basal transcription factors_Homo sapiens_hsa030220.74144676
38Vitamin digestion and absorption_Homo sapiens_hsa049770.72208045
39Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70952664
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65089418
41Axon guidance_Homo sapiens_hsa043600.64342149
42Mismatch repair_Homo sapiens_hsa034300.64151379
43Purine metabolism_Homo sapiens_hsa002300.62813390
44Olfactory transduction_Homo sapiens_hsa047400.62758211
45Circadian entrainment_Homo sapiens_hsa047130.62676410
46GABAergic synapse_Homo sapiens_hsa047270.62456644
47Fanconi anemia pathway_Homo sapiens_hsa034600.62233013
48Primary bile acid biosynthesis_Homo sapiens_hsa001200.60215110
49Morphine addiction_Homo sapiens_hsa050320.60108044
50Glutamatergic synapse_Homo sapiens_hsa047240.59154356
51Chemical carcinogenesis_Homo sapiens_hsa052040.58746828
52Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.58668835
53Selenocompound metabolism_Homo sapiens_hsa004500.57484625
54Nucleotide excision repair_Homo sapiens_hsa034200.55555153
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.54312532
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54047054
57Notch signaling pathway_Homo sapiens_hsa043300.53566727
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51996275
59Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.51291434
60Metabolic pathways_Homo sapiens_hsa011000.50668618
61Propanoate metabolism_Homo sapiens_hsa006400.50181649
62Pyruvate metabolism_Homo sapiens_hsa006200.47502776
63Cholinergic synapse_Homo sapiens_hsa047250.47183878
64Tryptophan metabolism_Homo sapiens_hsa003800.41488328
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40219166
66Linoleic acid metabolism_Homo sapiens_hsa005910.39862519
67Pyrimidine metabolism_Homo sapiens_hsa002400.38970059
68Alcoholism_Homo sapiens_hsa050340.37697864
69Pathways in cancer_Homo sapiens_hsa052000.37208265
70Ovarian steroidogenesis_Homo sapiens_hsa049130.36286659
71RNA transport_Homo sapiens_hsa030130.35394229
72Sulfur metabolism_Homo sapiens_hsa009200.34864122
73Peroxisome_Homo sapiens_hsa041460.32881657
74cAMP signaling pathway_Homo sapiens_hsa040240.31236634
75Amphetamine addiction_Homo sapiens_hsa050310.30288301
76Protein digestion and absorption_Homo sapiens_hsa049740.29712372
77Retinol metabolism_Homo sapiens_hsa008300.29423320
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.27993589
79Cell cycle_Homo sapiens_hsa041100.26927479
80Glutathione metabolism_Homo sapiens_hsa004800.24954024
81Calcium signaling pathway_Homo sapiens_hsa040200.23655175
82Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.23632839
83Mineral absorption_Homo sapiens_hsa049780.23258475
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.22642114
85Dopaminergic synapse_Homo sapiens_hsa047280.22008241
86Insulin secretion_Homo sapiens_hsa049110.21216552
87Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.19976236
88DNA replication_Homo sapiens_hsa030300.19674415
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19007279
90Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.18872945
91Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.18799614
92Arachidonic acid metabolism_Homo sapiens_hsa005900.17966739
93Bile secretion_Homo sapiens_hsa049760.16742748
94Systemic lupus erythematosus_Homo sapiens_hsa053220.15060401
95ECM-receptor interaction_Homo sapiens_hsa045120.14415518
96Caffeine metabolism_Homo sapiens_hsa002320.13120852
97Sulfur relay system_Homo sapiens_hsa041220.12122033
98Oocyte meiosis_Homo sapiens_hsa041140.10762100
99Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.10477508
100Tyrosine metabolism_Homo sapiens_hsa003500.09924290

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »