Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 8.63573429 |
2 | neuron fate determination (GO:0048664) | 8.45039585 |
3 | viral transcription (GO:0019083) | 8.30149529 |
4 | translational termination (GO:0006415) | 7.94166300 |
5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 7.36992284 |
6 | ATP synthesis coupled proton transport (GO:0015986) | 7.36992284 |
7 | cotranslational protein targeting to membrane (GO:0006613) | 6.80910723 |
8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.79220068 |
9 | protein targeting to ER (GO:0045047) | 6.67664509 |
10 | ribosomal small subunit assembly (GO:0000028) | 6.64808576 |
11 | translational elongation (GO:0006414) | 6.38921495 |
12 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.38266161 |
13 | * sequestering of actin monomers (GO:0042989) | 6.33878666 |
14 | cellular protein complex disassembly (GO:0043624) | 6.15111695 |
15 | protein localization to endoplasmic reticulum (GO:0070972) | 6.14881608 |
16 | viral life cycle (GO:0019058) | 5.88445041 |
17 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.74788100 |
18 | behavioral response to nicotine (GO:0035095) | 5.54311486 |
19 | respiratory electron transport chain (GO:0022904) | 5.31184864 |
20 | maturation of SSU-rRNA (GO:0030490) | 5.27298634 |
21 | electron transport chain (GO:0022900) | 5.23822636 |
22 | protein complex disassembly (GO:0043241) | 5.23775135 |
23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.22595717 |
24 | translational initiation (GO:0006413) | 5.20497543 |
25 | lateral sprouting from an epithelium (GO:0060601) | 5.02216039 |
26 | ribosomal small subunit biogenesis (GO:0042274) | 4.89620624 |
27 | macromolecular complex disassembly (GO:0032984) | 4.89610463 |
28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.84564247 |
29 | serotonin receptor signaling pathway (GO:0007210) | 4.78965878 |
30 | epithelial cilium movement (GO:0003351) | 4.70772771 |
31 | midbrain development (GO:0030901) | 4.59299318 |
32 | inner mitochondrial membrane organization (GO:0007007) | 4.49663214 |
33 | protein targeting to membrane (GO:0006612) | 4.47385388 |
34 | protein neddylation (GO:0045116) | 4.46463563 |
35 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.40731871 |
36 | limb bud formation (GO:0060174) | 4.27030839 |
37 | otic vesicle formation (GO:0030916) | 4.14161072 |
38 | intraciliary transport (GO:0042073) | 3.96754533 |
39 | cranial suture morphogenesis (GO:0060363) | 3.96523858 |
40 | ATP biosynthetic process (GO:0006754) | 3.89834634 |
41 | cilium movement (GO:0003341) | 3.87251148 |
42 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.76581885 |
43 | neuron fate specification (GO:0048665) | 3.73503388 |
44 | chaperone-mediated protein transport (GO:0072321) | 3.69637886 |
45 | hydrogen ion transmembrane transport (GO:1902600) | 3.68936535 |
46 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.65657725 |
47 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.62957183 |
48 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.62957183 |
49 | NADH dehydrogenase complex assembly (GO:0010257) | 3.62957183 |
50 | ribosomal large subunit biogenesis (GO:0042273) | 3.60519516 |
51 | mRNA catabolic process (GO:0006402) | 3.58369583 |
52 | protein complex biogenesis (GO:0070271) | 3.55772408 |
53 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.51396579 |
54 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.48088104 |
55 | presynaptic membrane assembly (GO:0097105) | 3.41104982 |
56 | axonemal dynein complex assembly (GO:0070286) | 3.39826013 |
57 | spinal cord association neuron differentiation (GO:0021527) | 3.38137402 |
58 | tongue development (GO:0043586) | 3.28862523 |
59 | proton transport (GO:0015992) | 3.27425110 |
60 | positive regulation of gastrulation (GO:2000543) | 3.25819617 |
61 | translation (GO:0006412) | 3.22967014 |
62 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.21903530 |
63 | hydrogen transport (GO:0006818) | 3.20581319 |
64 | neuronal stem cell maintenance (GO:0097150) | 3.14817454 |
65 | presynaptic membrane organization (GO:0097090) | 3.12573704 |
66 | RNA catabolic process (GO:0006401) | 3.11388899 |
67 | establishment of protein localization to membrane (GO:0090150) | 3.04387249 |
68 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.98231978 |
69 | retinal ganglion cell axon guidance (GO:0031290) | 2.94622950 |
70 | postsynaptic membrane organization (GO:0001941) | 2.91821735 |
71 | nonmotile primary cilium assembly (GO:0035058) | 2.91318557 |
72 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.91258674 |
73 | regulation of phospholipid biosynthetic process (GO:0071071) | 2.90189981 |
74 | kidney morphogenesis (GO:0060993) | 2.90158977 |
75 | craniofacial suture morphogenesis (GO:0097094) | 2.86665110 |
76 | spermatid nucleus differentiation (GO:0007289) | 2.83519739 |
77 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.83283743 |
78 | mesenchymal cell proliferation (GO:0010463) | 2.81637112 |
79 | embryonic digestive tract morphogenesis (GO:0048557) | 2.80381388 |
80 | cGMP biosynthetic process (GO:0006182) | 2.79419170 |
81 | somite development (GO:0061053) | 2.75120218 |
82 | neural tube formation (GO:0001841) | 2.71429876 |
83 | negative regulation of axon guidance (GO:1902668) | 2.69811464 |
84 | positive regulation of embryonic development (GO:0040019) | 2.64814227 |
85 | protein targeting (GO:0006605) | 2.64757111 |
86 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.62908134 |
87 | hematopoietic stem cell proliferation (GO:0071425) | 2.61393782 |
88 | establishment of protein localization to organelle (GO:0072594) | 2.60615970 |
89 | radial glial cell differentiation (GO:0060019) | 2.60384214 |
90 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.59243077 |
91 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.58366869 |
92 | axon extension involved in axon guidance (GO:0048846) | 2.58366869 |
93 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.52133670 |
94 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.52133670 |
95 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.52133670 |
96 | regulation of timing of cell differentiation (GO:0048505) | 2.52016872 |
97 | regulation of appetite (GO:0032098) | 2.51210213 |
98 | protein localization to membrane (GO:0072657) | 2.50192740 |
99 | lung lobe morphogenesis (GO:0060463) | 2.48817957 |
100 | digestive tract morphogenesis (GO:0048546) | 2.48141453 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.36342712 |
2 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 3.24773165 |
3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.08133199 |
4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.04520644 |
5 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.89596415 |
6 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.71048804 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.70196292 |
8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.69391185 |
9 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.43523286 |
10 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.43474199 |
11 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.29317119 |
12 | FUS_26573619_Chip-Seq_HEK293_Human | 2.28916993 |
13 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.25007918 |
14 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.21662957 |
15 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.20440927 |
16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.19460730 |
17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.15057105 |
18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.07292653 |
19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.05882592 |
20 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.00973813 |
21 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.00313298 |
22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.99789768 |
23 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.96244902 |
24 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.94913860 |
25 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.94330836 |
26 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.94020154 |
27 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.91345383 |
28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.88508832 |
29 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.87081222 |
30 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.87081222 |
31 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.84130251 |
32 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.78058022 |
33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.76524386 |
34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.72348508 |
35 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.71084899 |
36 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.68723551 |
37 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.66742634 |
38 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.63783366 |
39 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.63325464 |
40 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.63130606 |
41 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.62852418 |
42 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.62852418 |
43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.61478574 |
44 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.56682007 |
45 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.52272268 |
46 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.52231682 |
47 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.47269461 |
48 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.47115484 |
49 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.44496535 |
50 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.43876616 |
51 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.42756024 |
52 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.41345648 |
53 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.38561575 |
54 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.37403683 |
55 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.36914510 |
56 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.32042311 |
57 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.31802346 |
58 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.30722202 |
59 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.29108422 |
60 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.28429862 |
61 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26765230 |
62 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.25763264 |
63 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25098562 |
64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.24056395 |
65 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.20049214 |
66 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.17806271 |
67 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.17544208 |
68 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.14332067 |
69 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.13735675 |
70 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.13475702 |
71 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.13474759 |
72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.10434202 |
73 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.08872707 |
74 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08642744 |
75 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.08354042 |
76 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.08188937 |
77 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.04825955 |
78 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.04473830 |
79 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.04458448 |
80 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.04133591 |
81 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.03131872 |
82 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.02899900 |
83 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.01779668 |
84 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.96456246 |
85 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.94765949 |
86 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.94555805 |
87 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.94440812 |
88 | AR_25329375_ChIP-Seq_VCAP_Human | 0.94005744 |
89 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.93413643 |
90 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.93399336 |
91 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.93392523 |
92 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.93059612 |
93 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.93059612 |
94 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.93059612 |
95 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.91685232 |
96 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.91102664 |
97 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.90152737 |
98 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.89870197 |
99 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.89662038 |
100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.89333387 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000566_synostosis | 6.79917190 |
2 | MP0010030_abnormal_orbit_morphology | 5.89298376 |
3 | MP0009379_abnormal_foot_pigmentation | 4.88786982 |
4 | MP0003136_yellow_coat_color | 3.51412875 |
5 | MP0002938_white_spotting | 2.82878721 |
6 | MP0000372_irregular_coat_pigmentation | 2.67506001 |
7 | MP0001346_abnormal_lacrimal_gland | 2.58447114 |
8 | MP0002638_abnormal_pupillary_reflex | 2.47698533 |
9 | MP0000579_abnormal_nail_morphology | 2.38108221 |
10 | MP0003880_abnormal_central_pattern | 2.32441492 |
11 | MP0006292_abnormal_olfactory_placode | 2.26955718 |
12 | MP0003938_abnormal_ear_development | 2.14281031 |
13 | MP0008789_abnormal_olfactory_epithelium | 2.12258869 |
14 | MP0004142_abnormal_muscle_tone | 2.04713570 |
15 | MP0005171_absent_coat_pigmentation | 2.03740086 |
16 | MP0001529_abnormal_vocalization | 1.93438991 |
17 | MP0003283_abnormal_digestive_organ | 1.89108322 |
18 | MP0005423_abnormal_somatic_nervous | 1.88818264 |
19 | MP0000537_abnormal_urethra_morphology | 1.86655121 |
20 | MP0005499_abnormal_olfactory_system | 1.85273593 |
21 | MP0005394_taste/olfaction_phenotype | 1.85273593 |
22 | MP0002653_abnormal_ependyma_morphology | 1.77619871 |
23 | MP0000631_abnormal_neuroendocrine_gland | 1.72778266 |
24 | MP0006276_abnormal_autonomic_nervous | 1.68622746 |
25 | MP0003011_delayed_dark_adaptation | 1.65851008 |
26 | MP0002234_abnormal_pharynx_morphology | 1.64165709 |
27 | MP0000778_abnormal_nervous_system | 1.61514006 |
28 | MP0010386_abnormal_urinary_bladder | 1.57880054 |
29 | MP0004133_heterotaxia | 1.57501496 |
30 | MP0008995_early_reproductive_senescence | 1.55976069 |
31 | MP0008961_abnormal_basal_metabolism | 1.52673096 |
32 | MP0005084_abnormal_gallbladder_morpholo | 1.51893524 |
33 | MP0000026_abnormal_inner_ear | 1.51014835 |
34 | MP0001984_abnormal_olfaction | 1.46277261 |
35 | MP0006072_abnormal_retinal_apoptosis | 1.46132790 |
36 | MP0002282_abnormal_trachea_morphology | 1.44174537 |
37 | MP0002249_abnormal_larynx_morphology | 1.43922818 |
38 | MP0005248_abnormal_Harderian_gland | 1.40387861 |
39 | MP0003937_abnormal_limbs/digits/tail_de | 1.38680488 |
40 | MP0002233_abnormal_nose_morphology | 1.33466127 |
41 | MP0002697_abnormal_eye_size | 1.33004279 |
42 | MP0002736_abnormal_nociception_after | 1.32122548 |
43 | MP0001293_anophthalmia | 1.30452452 |
44 | MP0003122_maternal_imprinting | 1.24480885 |
45 | MP0001286_abnormal_eye_development | 1.24464474 |
46 | MP0000049_abnormal_middle_ear | 1.23521110 |
47 | MP0009250_abnormal_appendicular_skeleto | 1.16003851 |
48 | MP0005197_abnormal_uvea_morphology | 1.15747144 |
49 | MP0002822_catalepsy | 1.13074104 |
50 | MP0000462_abnormal_digestive_system | 1.05730463 |
51 | MP0002928_abnormal_bile_duct | 1.04905310 |
52 | MP0005187_abnormal_penis_morphology | 1.02981566 |
53 | MP0002295_abnormal_pulmonary_circulatio | 1.00885312 |
54 | MP0004742_abnormal_vestibular_system | 0.99526974 |
55 | MP0001440_abnormal_grooming_behavior | 0.96986186 |
56 | MP0002734_abnormal_mechanical_nocicepti | 0.96566590 |
57 | MP0005253_abnormal_eye_physiology | 0.96456332 |
58 | MP0001324_abnormal_eye_pigmentation | 0.95768979 |
59 | MP0001968_abnormal_touch/_nociception | 0.95449141 |
60 | MP0001486_abnormal_startle_reflex | 0.94792559 |
61 | MP0005551_abnormal_eye_electrophysiolog | 0.92863711 |
62 | MP0000647_abnormal_sebaceous_gland | 0.90865011 |
63 | MP0002752_abnormal_somatic_nervous | 0.89410928 |
64 | MP0002184_abnormal_innervation | 0.88894522 |
65 | MP0003755_abnormal_palate_morphology | 0.88689780 |
66 | MP0009745_abnormal_behavioral_response | 0.86970827 |
67 | MP0003861_abnormal_nervous_system | 0.85246923 |
68 | MP0002102_abnormal_ear_morphology | 0.84850499 |
69 | MP0005195_abnormal_posterior_eye | 0.82917890 |
70 | MP0001485_abnormal_pinna_reflex | 0.82432907 |
71 | MP0005391_vision/eye_phenotype | 0.81230115 |
72 | MP0005408_hypopigmentation | 0.80977657 |
73 | MP0002272_abnormal_nervous_system | 0.80696366 |
74 | MP0002572_abnormal_emotion/affect_behav | 0.78977164 |
75 | MP0003942_abnormal_urinary_system | 0.78403257 |
76 | MP0002064_seizures | 0.76317524 |
77 | MP0000762_abnormal_tongue_morphology | 0.76303116 |
78 | MP0001299_abnormal_eye_distance/ | 0.75302949 |
79 | MP0003315_abnormal_perineum_morphology | 0.71791120 |
80 | MP0003121_genomic_imprinting | 0.71164492 |
81 | MP0009053_abnormal_anal_canal | 0.70824618 |
82 | MP0000955_abnormal_spinal_cord | 0.70651614 |
83 | MP0002557_abnormal_social/conspecific_i | 0.69595268 |
84 | MP0002882_abnormal_neuron_morphology | 0.67939671 |
85 | MP0005646_abnormal_pituitary_gland | 0.67831767 |
86 | MP0002932_abnormal_joint_morphology | 0.67522086 |
87 | MP0002751_abnormal_autonomic_nervous | 0.66610926 |
88 | MP0000383_abnormal_hair_follicle | 0.66431109 |
89 | MP0003959_abnormal_lean_body | 0.65549480 |
90 | MP0004885_abnormal_endolymph | 0.64881014 |
91 | MP0002095_abnormal_skin_pigmentation | 0.64430585 |
92 | MP0003385_abnormal_body_wall | 0.62556830 |
93 | MP0002152_abnormal_brain_morphology | 0.62472637 |
94 | MP0001963_abnormal_hearing_physiology | 0.62108336 |
95 | MP0002116_abnormal_craniofacial_bone | 0.61899836 |
96 | MP0002277_abnormal_respiratory_mucosa | 0.61202288 |
97 | MP0001879_abnormal_lymphatic_vessel | 0.60934358 |
98 | MP0005645_abnormal_hypothalamus_physiol | 0.59795094 |
99 | MP0003119_abnormal_digestive_system | 0.58849125 |
100 | MP0003638_abnormal_response/metabolism_ | 0.58725703 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormal number of erythroid precursors (HP:0012131) | 4.75115590 |
2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.60841395 |
3 | Increased hepatocellular lipid droplets (HP:0006565) | 4.59201836 |
4 | Congenital, generalized hypertrichosis (HP:0004540) | 4.23233298 |
5 | Concave nail (HP:0001598) | 3.96682358 |
6 | Partial duplication of thumb phalanx (HP:0009944) | 3.96286545 |
7 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.94435567 |
8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.92667352 |
9 | Abnormal ciliary motility (HP:0012262) | 3.77763309 |
10 | Macrocytic anemia (HP:0001972) | 3.69228939 |
11 | Partial duplication of the phalanx of hand (HP:0009999) | 3.66989911 |
12 | Reticulocytopenia (HP:0001896) | 3.66125318 |
13 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.65696555 |
14 | Renal Fanconi syndrome (HP:0001994) | 3.65051811 |
15 | Mitochondrial inheritance (HP:0001427) | 3.60891123 |
16 | Esophageal atresia (HP:0002032) | 3.56794722 |
17 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.51296549 |
18 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.51296549 |
19 | Stenosis of the external auditory canal (HP:0000402) | 3.28913512 |
20 | Abnormality of the labia minora (HP:0012880) | 3.23709784 |
21 | Acute necrotizing encephalopathy (HP:0006965) | 3.20405175 |
22 | Split foot (HP:0001839) | 3.19854646 |
23 | Rhinitis (HP:0012384) | 3.18930479 |
24 | Hepatocellular necrosis (HP:0001404) | 3.11978853 |
25 | Abnormality of the parietal bone (HP:0002696) | 3.11131147 |
26 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.93731434 |
27 | Rib fusion (HP:0000902) | 2.93530045 |
28 | Septo-optic dysplasia (HP:0100842) | 2.92998878 |
29 | Exertional dyspnea (HP:0002875) | 2.91110523 |
30 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.88576876 |
31 | Focal motor seizures (HP:0011153) | 2.88032712 |
32 | Hepatic necrosis (HP:0002605) | 2.82831057 |
33 | Increased CSF lactate (HP:0002490) | 2.77978443 |
34 | Absent septum pellucidum (HP:0001331) | 2.73703727 |
35 | Synostosis involving the elbow (HP:0003938) | 2.71484869 |
36 | Humeroradial synostosis (HP:0003041) | 2.71484869 |
37 | Chronic otitis media (HP:0000389) | 2.71217062 |
38 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.64005257 |
39 | 3-Methylglutaconic aciduria (HP:0003535) | 2.63855934 |
40 | Respiratory difficulties (HP:0002880) | 2.62712751 |
41 | Broad metatarsal (HP:0001783) | 2.61034754 |
42 | Acute encephalopathy (HP:0006846) | 2.60142644 |
43 | Progressive macrocephaly (HP:0004481) | 2.52978245 |
44 | Pallor (HP:0000980) | 2.49192908 |
45 | Absent/shortened dynein arms (HP:0200106) | 2.46103475 |
46 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.46103475 |
47 | Chronic sinusitis (HP:0011109) | 2.44729108 |
48 | Myokymia (HP:0002411) | 2.43284198 |
49 | Sleep apnea (HP:0010535) | 2.39736823 |
50 | Gastrointestinal atresia (HP:0002589) | 2.39565889 |
51 | Abnormality of renal resorption (HP:0011038) | 2.38347071 |
52 | Abnormality of the 2nd finger (HP:0004100) | 2.36461539 |
53 | Pancreatic fibrosis (HP:0100732) | 2.33809462 |
54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.30253037 |
55 | Genital tract atresia (HP:0001827) | 2.28441718 |
56 | Nephronophthisis (HP:0000090) | 2.27204188 |
57 | Vaginal atresia (HP:0000148) | 2.24695518 |
58 | Nasolacrimal duct obstruction (HP:0000579) | 2.21091584 |
59 | Coronal craniosynostosis (HP:0004440) | 2.20790126 |
60 | Hypoplasia of the pons (HP:0012110) | 2.17688121 |
61 | Glycosuria (HP:0003076) | 2.12302519 |
62 | Abnormality of urine glucose concentration (HP:0011016) | 2.12302519 |
63 | Abnormality of the septum pellucidum (HP:0007375) | 2.11026088 |
64 | Molar tooth sign on MRI (HP:0002419) | 2.09063287 |
65 | Abnormality of midbrain morphology (HP:0002418) | 2.09063287 |
66 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.07544744 |
67 | Aplasia of the phalanges of the hand (HP:0009802) | 2.07544744 |
68 | Aplasia involving bones of the extremities (HP:0009825) | 2.07544744 |
69 | Pancreatic cysts (HP:0001737) | 2.05770218 |
70 | Hyperphosphaturia (HP:0003109) | 2.05040757 |
71 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 2.04700570 |
72 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.02989583 |
73 | Stomach cancer (HP:0012126) | 2.01528119 |
74 | Cutaneous finger syndactyly (HP:0010554) | 2.01240414 |
75 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.00820912 |
76 | Trigonocephaly (HP:0000243) | 2.00602834 |
77 | Duplication of thumb phalanx (HP:0009942) | 2.00419901 |
78 | Broad distal phalanx of finger (HP:0009836) | 1.99491436 |
79 | Short hallux (HP:0010109) | 1.98029234 |
80 | Medial flaring of the eyebrow (HP:0010747) | 1.97708986 |
81 | Abnormality of the lacrimal duct (HP:0011481) | 1.96791492 |
82 | Taurodontia (HP:0000679) | 1.96153891 |
83 | Abnormality of permanent molar morphology (HP:0011071) | 1.96153891 |
84 | Abnormality of the dental root (HP:0006486) | 1.96153891 |
85 | Optic disc pallor (HP:0000543) | 1.95854452 |
86 | Oligodactyly (hands) (HP:0001180) | 1.92448855 |
87 | Abnormality of the pons (HP:0007361) | 1.91697005 |
88 | True hermaphroditism (HP:0010459) | 1.90958069 |
89 | Hypoplasia of the ulna (HP:0003022) | 1.90491657 |
90 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.87129161 |
91 | Abnormality of the renal medulla (HP:0100957) | 1.86518261 |
92 | Oligodactyly (HP:0012165) | 1.85202563 |
93 | Recurrent corneal erosions (HP:0000495) | 1.84097769 |
94 | Woolly hair (HP:0002224) | 1.83606060 |
95 | Abnormality of the nasolacrimal system (HP:0000614) | 1.81405136 |
96 | Polyphagia (HP:0002591) | 1.81201658 |
97 | Depressed nasal ridge (HP:0000457) | 1.80347059 |
98 | Abnormality of incisor morphology (HP:0011063) | 1.80015116 |
99 | Turricephaly (HP:0000262) | 1.79401143 |
100 | Short nail (HP:0001799) | 1.79233285 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FGFR2 | 5.28754838 |
2 | TLK1 | 4.53093635 |
3 | PNCK | 3.39492703 |
4 | VRK2 | 3.19585724 |
5 | TNIK | 2.96923353 |
6 | PASK | 2.94564677 |
7 | CASK | 2.94401149 |
8 | MAP3K4 | 2.88707007 |
9 | WNK3 | 2.48706313 |
10 | MARK1 | 2.40949509 |
11 | MAPK15 | 2.24106085 |
12 | NME1 | 2.07219479 |
13 | EPHB2 | 1.97645987 |
14 | EPHA3 | 1.95380229 |
15 | MAP2K7 | 1.89109488 |
16 | DYRK2 | 1.85088416 |
17 | DYRK3 | 1.78375700 |
18 | INSRR | 1.76154097 |
19 | ZAK | 1.76011885 |
20 | NUAK1 | 1.73854807 |
21 | WEE1 | 1.68546455 |
22 | VRK1 | 1.67106322 |
23 | MAP2K4 | 1.59130956 |
24 | BUB1 | 1.50813997 |
25 | TGFBR1 | 1.43887735 |
26 | CAMK1G | 1.38908599 |
27 | CDK8 | 1.33268471 |
28 | LRRK2 | 1.29749424 |
29 | PAK3 | 1.29504399 |
30 | GRK7 | 1.27738789 |
31 | ADRBK2 | 1.19082543 |
32 | STK38L | 1.18427684 |
33 | MAP3K12 | 1.15146603 |
34 | CCNB1 | 1.11553037 |
35 | UHMK1 | 1.10403045 |
36 | NTRK2 | 1.09819799 |
37 | TAF1 | 1.09759455 |
38 | FGFR1 | 1.01124303 |
39 | STK24 | 0.94526643 |
40 | SRPK1 | 0.92737819 |
41 | PRKCG | 0.86086129 |
42 | GRK1 | 0.84746847 |
43 | MAP4K2 | 0.80368393 |
44 | ADRBK1 | 0.78383949 |
45 | EPHA4 | 0.77184898 |
46 | SGK223 | 0.74010349 |
47 | SGK494 | 0.74010349 |
48 | BMPR1B | 0.73435535 |
49 | PINK1 | 0.70754269 |
50 | STK16 | 0.69986907 |
51 | PLK4 | 0.67183832 |
52 | AKT3 | 0.65993549 |
53 | MINK1 | 0.64293339 |
54 | MAPK13 | 0.63218516 |
55 | CAMK1 | 0.62752295 |
56 | AURKB | 0.62489597 |
57 | MUSK | 0.61636929 |
58 | PRKG1 | 0.59295106 |
59 | OBSCN | 0.56925389 |
60 | DDR2 | 0.54967498 |
61 | MAP3K10 | 0.54917414 |
62 | PLK3 | 0.54538707 |
63 | MKNK1 | 0.53905223 |
64 | MAP3K9 | 0.53641372 |
65 | CDK3 | 0.53259565 |
66 | NEK2 | 0.50826858 |
67 | STK3 | 0.50707382 |
68 | RPS6KA4 | 0.50132266 |
69 | NTRK3 | 0.49342869 |
70 | SGK2 | 0.49244079 |
71 | DYRK1A | 0.45554588 |
72 | PRKACA | 0.45343903 |
73 | TAOK3 | 0.39667095 |
74 | NLK | 0.38244813 |
75 | CSNK2A1 | 0.35604142 |
76 | MAP3K6 | 0.35055817 |
77 | AURKA | 0.34552373 |
78 | WNK4 | 0.33045425 |
79 | DYRK1B | 0.32539151 |
80 | SIK2 | 0.31674307 |
81 | STK11 | 0.30761210 |
82 | RPS6KA5 | 0.30715374 |
83 | CDK19 | 0.29645175 |
84 | CSNK2A2 | 0.28721430 |
85 | MAP3K11 | 0.28599027 |
86 | TYRO3 | 0.28455769 |
87 | PRKCE | 0.27868836 |
88 | CHUK | 0.27565273 |
89 | TIE1 | 0.27323147 |
90 | PRKACB | 0.26966857 |
91 | CAMK1D | 0.26427639 |
92 | PHKG1 | 0.26214450 |
93 | PHKG2 | 0.26214450 |
94 | BCKDK | 0.25318456 |
95 | DAPK3 | 0.24125970 |
96 | IRAK2 | 0.23949016 |
97 | CAMK2A | 0.23362977 |
98 | OXSR1 | 0.22239975 |
99 | CSNK1E | 0.20680172 |
100 | CHEK2 | 0.20671712 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 6.33131928 |
2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 6.06996484 |
3 | Parkinsons disease_Homo sapiens_hsa05012 | 5.02925903 |
4 | Alzheimers disease_Homo sapiens_hsa05010 | 3.77031245 |
5 | Huntingtons disease_Homo sapiens_hsa05016 | 3.73538173 |
6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.40693850 |
7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 3.29800096 |
8 | Proteasome_Homo sapiens_hsa03050 | 2.76507329 |
9 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.69179633 |
10 | Protein export_Homo sapiens_hsa03060 | 2.57461309 |
11 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 2.00016371 |
12 | Nicotine addiction_Homo sapiens_hsa05033 | 1.90929972 |
13 | RNA polymerase_Homo sapiens_hsa03020 | 1.77210736 |
14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.50816334 |
15 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.25529153 |
16 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.23243402 |
17 | Taste transduction_Homo sapiens_hsa04742 | 1.14917528 |
18 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.09635887 |
19 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.03424971 |
20 | Phototransduction_Homo sapiens_hsa04744 | 1.02061984 |
21 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.99250986 |
22 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.97111707 |
23 | Homologous recombination_Homo sapiens_hsa03440 | 0.96355664 |
24 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.94854999 |
25 | Melanogenesis_Homo sapiens_hsa04916 | 0.93331367 |
26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93173169 |
27 | Spliceosome_Homo sapiens_hsa03040 | 0.89426499 |
28 | Cocaine addiction_Homo sapiens_hsa05030 | 0.87578690 |
29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.86284444 |
30 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.83668840 |
31 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.81817291 |
32 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.78412116 |
33 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.77694995 |
34 | RNA degradation_Homo sapiens_hsa03018 | 0.77439797 |
35 | Gap junction_Homo sapiens_hsa04540 | 0.77318023 |
36 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.76484273 |
37 | Basal transcription factors_Homo sapiens_hsa03022 | 0.74144676 |
38 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.72208045 |
39 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.70952664 |
40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65089418 |
41 | Axon guidance_Homo sapiens_hsa04360 | 0.64342149 |
42 | Mismatch repair_Homo sapiens_hsa03430 | 0.64151379 |
43 | Purine metabolism_Homo sapiens_hsa00230 | 0.62813390 |
44 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62758211 |
45 | Circadian entrainment_Homo sapiens_hsa04713 | 0.62676410 |
46 | GABAergic synapse_Homo sapiens_hsa04727 | 0.62456644 |
47 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.62233013 |
48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60215110 |
49 | Morphine addiction_Homo sapiens_hsa05032 | 0.60108044 |
50 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.59154356 |
51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58746828 |
52 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.58668835 |
53 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.57484625 |
54 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.55555153 |
55 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.54312532 |
56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54047054 |
57 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.53566727 |
58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51996275 |
59 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.51291434 |
60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50668618 |
61 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.50181649 |
62 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47502776 |
63 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.47183878 |
64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.41488328 |
65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.40219166 |
66 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.39862519 |
67 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.38970059 |
68 | Alcoholism_Homo sapiens_hsa05034 | 0.37697864 |
69 | Pathways in cancer_Homo sapiens_hsa05200 | 0.37208265 |
70 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.36286659 |
71 | RNA transport_Homo sapiens_hsa03013 | 0.35394229 |
72 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.34864122 |
73 | Peroxisome_Homo sapiens_hsa04146 | 0.32881657 |
74 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.31236634 |
75 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.30288301 |
76 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.29712372 |
77 | Retinol metabolism_Homo sapiens_hsa00830 | 0.29423320 |
78 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27993589 |
79 | Cell cycle_Homo sapiens_hsa04110 | 0.26927479 |
80 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.24954024 |
81 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.23655175 |
82 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.23632839 |
83 | Mineral absorption_Homo sapiens_hsa04978 | 0.23258475 |
84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.22642114 |
85 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.22008241 |
86 | Insulin secretion_Homo sapiens_hsa04911 | 0.21216552 |
87 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.19976236 |
88 | DNA replication_Homo sapiens_hsa03030 | 0.19674415 |
89 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.19007279 |
90 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.18872945 |
91 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.18799614 |
92 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.17966739 |
93 | Bile secretion_Homo sapiens_hsa04976 | 0.16742748 |
94 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.15060401 |
95 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.14415518 |
96 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.13120852 |
97 | Sulfur relay system_Homo sapiens_hsa04122 | 0.12122033 |
98 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.10762100 |
99 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.10477508 |
100 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.09924290 |