TNFAIP8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.17186622
2positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.93338055
3negative regulation of interleukin-12 production (GO:0032695)4.79362539
4antigen processing and presentation of endogenous antigen (GO:0019883)4.77453662
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.77006855
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.77006855
7positive regulation of gamma-delta T cell activation (GO:0046645)4.51660203
8ribosomal small subunit assembly (GO:0000028)4.40523920
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.32059564
10negative regulation of cell killing (GO:0031342)4.32059564
11regulation of chronic inflammatory response (GO:0002676)4.22796166
12regulation of vitamin D biosynthetic process (GO:0060556)4.15864098
13regulation of T-helper 1 cell differentiation (GO:0045625)4.09680028
14regulation of B cell receptor signaling pathway (GO:0050855)4.03742205
15regulation of interleukin-2 biosynthetic process (GO:0045076)3.70062813
16immunoglobulin mediated immune response (GO:0016064)3.69918545
17positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.68827349
18positive regulation of B cell differentiation (GO:0045579)3.68739206
19negative regulation of phagocytosis (GO:0050765)3.66862423
20negative regulation of T cell mediated immunity (GO:0002710)3.66340749
21tolerance induction (GO:0002507)3.61031251
22mast cell activation (GO:0045576)3.56529124
23definitive hemopoiesis (GO:0060216)3.48807627
24regulation of B cell differentiation (GO:0045577)3.43589854
25response to interferon-beta (GO:0035456)3.41380363
26neutrophil activation involved in immune response (GO:0002283)3.40548160
27lipopolysaccharide-mediated signaling pathway (GO:0031663)3.38681858
28cellular response to zinc ion (GO:0071294)3.33946086
29regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.33857455
30regulation of T cell tolerance induction (GO:0002664)3.33722838
31leukocyte aggregation (GO:0070486)3.33395845
32myeloid dendritic cell activation (GO:0001773)3.32846361
33positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.32155643
34defense response to protozoan (GO:0042832)3.29850823
35regulation of interleukin-12 production (GO:0032655)3.28949349
36B cell receptor signaling pathway (GO:0050853)3.28416184
37positive regulation by symbiont of host defense response (GO:0052509)3.24481329
38modulation by symbiont of host defense response (GO:0052031)3.24481329
39modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.24481329
40modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.24481329
41positive regulation by organism of defense response of other organism involved in symbiotic interact3.24481329
42modulation by symbiont of host immune response (GO:0052553)3.24481329
43regulation of vitamin metabolic process (GO:0030656)3.24081813
44regulation of interleukin-12 biosynthetic process (GO:0045075)3.23296920
45response to interleukin-15 (GO:0070672)3.22161261
46cellular response to interleukin-15 (GO:0071350)3.22051232
47positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.20956203
48positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.19855774
49CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.19470338
50regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.19369671
51positive regulation of defense response to virus by host (GO:0002230)3.19133183
52positive regulation of interleukin-2 production (GO:0032743)3.18925216
53positive regulation of B cell mediated immunity (GO:0002714)3.18546803
54positive regulation of immunoglobulin mediated immune response (GO:0002891)3.18546803
55cellular response to interferon-beta (GO:0035458)3.18163301
56negative regulation of cytokine production involved in immune response (GO:0002719)3.17730913
57Arp2/3 complex-mediated actin nucleation (GO:0034314)3.17648660
58positive regulation of type 2 immune response (GO:0002830)3.16503727
59response to protozoan (GO:0001562)3.15370091
60positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.13001838
61positive regulation of heat generation (GO:0031652)3.12226792
62response to peptidoglycan (GO:0032494)3.09822360
63positive regulation of humoral immune response (GO:0002922)3.09690159
64regulation of regulatory T cell differentiation (GO:0045589)3.09588479
65positive regulation of antigen processing and presentation (GO:0002579)3.08905497
66regulation of gamma-delta T cell activation (GO:0046643)3.08866103
67regulation of gamma-delta T cell differentiation (GO:0045586)3.08777876
68respiratory burst (GO:0045730)3.08126076
69positive regulation of chemokine biosynthetic process (GO:0045080)3.07463382
70lymphocyte chemotaxis (GO:0048247)3.07451639
71response to type I interferon (GO:0034340)3.07178707
72positive regulation of NF-kappaB import into nucleus (GO:0042346)3.06973218
73cellular response to type I interferon (GO:0071357)3.06967554
74type I interferon signaling pathway (GO:0060337)3.06967554
75regulation of cytokine secretion involved in immune response (GO:0002739)3.06721321
76regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)3.05313775
77positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.04444439
78B cell mediated immunity (GO:0019724)3.04161031
79regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04019571
80antigen processing and presentation via MHC class Ib (GO:0002475)3.03312346
81interferon-gamma-mediated signaling pathway (GO:0060333)3.02065347
82viral transcription (GO:0019083)3.00878555
83negative regulation of viral genome replication (GO:0045071)2.98911296
84T cell migration (GO:0072678)2.97578855
85regulation of T-helper cell differentiation (GO:0045622)2.97265510
86aminoglycoside antibiotic metabolic process (GO:0030647)2.96966986
87regulation of tolerance induction (GO:0002643)2.96820587
88NIK/NF-kappaB signaling (GO:0038061)2.94799698
89regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.94368987
90regulation of natural killer cell mediated immunity (GO:0002715)2.94368987
91regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.93747953
92regulation of chemokine biosynthetic process (GO:0045073)2.93602596
93positive regulation of interleukin-12 production (GO:0032735)2.93477970
94interferon-gamma production (GO:0032609)2.92259879
95megakaryocyte development (GO:0035855)2.91905236
96regulation of fever generation (GO:0031620)2.91806261
97regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.91637596
98production of molecular mediator involved in inflammatory response (GO:0002532)2.91380442
99daunorubicin metabolic process (GO:0044597)2.90877967
100polyketide metabolic process (GO:0030638)2.90877967
101doxorubicin metabolic process (GO:0044598)2.90877967
102regulation of immunoglobulin secretion (GO:0051023)2.90674592
103positive regulation of cytokine biosynthetic process (GO:0042108)2.90104936
104cellular response to interferon-gamma (GO:0071346)2.89788965
105germinal center formation (GO:0002467)2.89375856
106regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.89323950
107regulation of T-helper 1 type immune response (GO:0002825)2.87195168
108translational termination (GO:0006415)2.87135896
109regulation of inflammatory response to antigenic stimulus (GO:0002861)2.86913277
110response to muramyl dipeptide (GO:0032495)2.86904709
111regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.82694853
112regulation of podosome assembly (GO:0071801)2.82597339
113regulation of T cell receptor signaling pathway (GO:0050856)2.80728047
114myeloid dendritic cell differentiation (GO:0043011)2.77367558
115response to interferon-alpha (GO:0035455)2.76183447
116neutrophil activation (GO:0042119)2.76032885
117regulation of interferon-beta biosynthetic process (GO:0045357)2.75867343
118myeloid cell activation involved in immune response (GO:0002275)2.72134594
119cellular response to exogenous dsRNA (GO:0071360)2.72060370
120positive regulation of interferon-alpha production (GO:0032727)2.70525946
121pinocytosis (GO:0006907)2.68205684
122positive regulation of macrophage differentiation (GO:0045651)2.67917581
123dendritic cell migration (GO:0036336)2.67776902
124negative thymic T cell selection (GO:0045060)2.67598215
125T cell homeostasis (GO:0043029)2.66500681
126regulation of alpha-beta T cell proliferation (GO:0046640)2.65406242
127T-helper 1 type immune response (GO:0042088)2.64904680
128negative T cell selection (GO:0043383)2.63370021
129ribosomal small subunit biogenesis (GO:0042274)2.62210526
130regulation of antigen processing and presentation (GO:0002577)2.62091117
131positive thymic T cell selection (GO:0045059)2.61537366
132regulation of interferon-alpha production (GO:0032647)2.60583657
133regulation of hypersensitivity (GO:0002883)2.58511032
134platelet dense granule organization (GO:0060155)2.56144100
135positive regulation of alpha-beta T cell proliferation (GO:0046641)2.55483596
136lymph node development (GO:0048535)2.55353857
137cellular extravasation (GO:0045123)2.54432012
138SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.53609785
139dendritic cell differentiation (GO:0097028)2.53269534
140granulocyte activation (GO:0036230)2.52748099
141detection of other organism (GO:0098543)2.50670479
142lymphocyte homeostasis (GO:0002260)2.50104193
143regulation of response to interferon-gamma (GO:0060330)2.49262776
144hepatocyte apoptotic process (GO:0097284)2.48233019
145mature B cell differentiation (GO:0002335)2.47718336
146regulation of MHC class II biosynthetic process (GO:0045346)2.47213557
147actin nucleation (GO:0045010)2.47097521
148myeloid leukocyte activation (GO:0002274)2.46387605
149mature B cell differentiation involved in immune response (GO:0002313)2.45692409
150macrophage activation involved in immune response (GO:0002281)2.45469960
151cotranslational protein targeting to membrane (GO:0006613)2.45221771
152angiogenesis involved in wound healing (GO:0060055)2.45195060
153neutrophil mediated immunity (GO:0002446)2.45095363
154protein targeting to ER (GO:0045047)2.44460470

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.25779479
2E2F7_22180533_ChIP-Seq_HELA_Human4.45715374
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.20512892
4IRF8_21731497_ChIP-ChIP_J774_Mouse4.10721761
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.01756481
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.74148317
7* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.54678678
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.54565955
9* SCL_19346495_ChIP-Seq_HPC-7_Human3.15329892
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.08469529
11SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.06356267
12IRF8_27001747_Chip-Seq_BMDM_Mouse2.77689445
13* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.77187443
14* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.75305188
15* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.67760456
16STAT4_19710469_ChIP-ChIP_TH1__Mouse2.60241700
17* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.58163063
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.56998788
19* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.54480047
20* SPI1_23547873_ChIP-Seq_NB4_Human2.49969677
21EGR1_19374776_ChIP-ChIP_THP-1_Human2.45355993
22MYB_26560356_Chip-Seq_TH2_Human2.31323574
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.30803665
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.21414548
25SMAD_19615063_ChIP-ChIP_OVARY_Human2.19268872
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.09845388
27* RUNX_20019798_ChIP-Seq_JUKART_Human2.06126681
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.04783521
29VDR_21846776_ChIP-Seq_THP-1_Human2.01699767
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.99301558
31MYC_22102868_ChIP-Seq_BL_Human1.97509189
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.96403584
33TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.93433567
34MAF_26560356_Chip-Seq_TH1_Human1.93154010
35MYB_26560356_Chip-Seq_TH1_Human1.90702300
36VDR_24763502_ChIP-Seq_THP-1_Human1.89292810
37* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.84093711
38NOTCH1_21737748_ChIP-Seq_TLL_Human1.78003362
39MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.77547836
40LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.76759427
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.74167065
42LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.70341305
43NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.69535207
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.69124885
45ERG_20887958_ChIP-Seq_HPC-7_Mouse1.68412139
46E2F4_17652178_ChIP-ChIP_JURKAT_Human1.66937242
47EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.64447300
48RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.63948419
49CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.60117989
50UTX_26944678_Chip-Seq_JUKART_Human1.59958922
51GATA1_22025678_ChIP-Seq_K562_Human1.55122315
52GATA2_22383799_ChIP-Seq_G1ME_Mouse1.53592926
53PU_27001747_Chip-Seq_BMDM_Mouse1.47239166
54* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.46961267
55GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.43950146
56STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.43127317
57NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.42016944
58VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.40059925
59VDR_23849224_ChIP-Seq_CD4+_Human1.35824447
60TP63_17297297_ChIP-ChIP_HaCaT_Human1.33519649
61GATA1_22383799_ChIP-Seq_G1ME_Mouse1.33339701
62* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.32237960
63GATA3_27048872_Chip-Seq_THYMUS_Human1.31578351
64GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.30031344
65* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.29837341
66FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.28748594
67FOXM1_23109430_ChIP-Seq_U2OS_Human1.28197922
68SPI1_23127762_ChIP-Seq_K562_Human1.27638971
69* TCF7_22412390_ChIP-Seq_EML_Mouse1.21810676
70GATA3_26560356_Chip-Seq_TH2_Human1.21103265
71* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.19115324
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.17464681
73ELK1_19687146_ChIP-ChIP_HELA_Human1.16746967
74FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.15555881
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.15436285
76FOXP3_21729870_ChIP-Seq_TREG_Human1.14636717
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.13427204
78VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.10217443
79MAF_26560356_Chip-Seq_TH2_Human1.09652423
80* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09305297
81MYC_18555785_ChIP-Seq_MESCs_Mouse1.05894236
82E2F1_21310950_ChIP-Seq_MCF-7_Human1.03222801
83* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01653221
84PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01593060
85PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98265178
86GABP_17652178_ChIP-ChIP_JURKAT_Human0.98076561
87* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96911353
88* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95648129
89EST1_17652178_ChIP-ChIP_JURKAT_Human0.95589270
90* SMRT_27268052_Chip-Seq_Bcells_Human0.92874628
91PU.1_20513432_ChIP-Seq_Bcells_Mouse0.91759883
92ETS1_22383799_ChIP-Seq_G1ME_Mouse0.89439804
93SRF_21415370_ChIP-Seq_HL-1_Mouse0.88994253
94PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87962747
95GATA1_19941827_ChIP-Seq_MEL_Mouse0.86717077
96GATA2_21666600_ChIP-Seq_HMVEC_Human0.85737441
97* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85721790
98TFEB_21752829_ChIP-Seq_HELA_Human0.85312803
99CIITA_25753668_ChIP-Seq_RAJI_Human0.84423602
100NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.83346424
101* STAT1_20625510_ChIP-Seq_HELA_Human0.83236398
102MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.82765520
103VDR_24787735_ChIP-Seq_THP-1_Human0.82029683
104RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81253930
105GATA3_26560356_Chip-Seq_TH1_Human0.80297512
106CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.79854360
107FLI1_27457419_Chip-Seq_LIVER_Mouse0.78224636
108* GATA1_19941826_ChIP-Seq_K562_Human0.77196981
109KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.77178095
110EGR1_23403033_ChIP-Seq_LIVER_Mouse0.76119905
111CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.76009786
112BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.75230871
113PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.72137445
114KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.71697039
115* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71240627
116CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71235336
117FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.64929674
118SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.63355933
119RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.63162454
120* GATA2_19941826_ChIP-Seq_K562_Human0.61053930
121JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.60989626
122BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.59275210
123EGR1_19032775_ChIP-ChIP_M12_Human0.59130716

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.38505374
2MP0009785_altered_susceptibility_to3.23895166
3MP0005671_abnormal_response_to3.20691158
4MP0000685_abnormal_immune_system3.19475803
5MP0002396_abnormal_hematopoietic_system3.05585028
6MP0002148_abnormal_hypersensitivity_rea2.80398577
7MP0001800_abnormal_humoral_immune2.80197765
8MP0003436_decreased_susceptibility_to2.71050403
9MP0005000_abnormal_immune_tolerance2.68533371
10MP0001790_abnormal_immune_system2.68080006
11MP0005387_immune_system_phenotype2.68080006
12MP0005025_abnormal_response_to2.64645439
13MP0002452_abnormal_antigen_presenting2.62085913
14MP0003763_abnormal_thymus_physiology2.57345584
15MP0002419_abnormal_innate_immunity2.48252386
16MP0002420_abnormal_adaptive_immunity2.46880635
17MP0002723_abnormal_immune_serum2.45987965
18MP0001819_abnormal_immune_cell2.44461300
19MP0003724_increased_susceptibility_to2.29413029
20MP0002166_altered_tumor_susceptibility2.24140325
21MP0002398_abnormal_bone_marrow2.20938346
22MP0005464_abnormal_platelet_physiology2.18497640
23MP0001853_heart_inflammation2.03546848
24MP0002405_respiratory_system_inflammati2.01031055
25MP0000716_abnormal_immune_system2.00125555
26MP0002006_tumorigenesis1.98269188
27MP0010155_abnormal_intestine_physiology1.92272310
28MP0000689_abnormal_spleen_morphology1.88533770
29MP0005174_abnormal_tail_pigmentation1.86174234
30MP0002722_abnormal_immune_system1.80959519
31MP0004808_abnormal_hematopoietic_stem1.80957414
32MP0001873_stomach_inflammation1.79426814
33MP0003303_peritoneal_inflammation1.78345437
34MP0009333_abnormal_splenocyte_physiolog1.75945521
35MP0000465_gastrointestinal_hemorrhage1.74818837
36MP0005397_hematopoietic_system_phenotyp1.73199494
37MP0001545_abnormal_hematopoietic_system1.73199494
38MP0002429_abnormal_blood_cell1.71659451
39MP0001845_abnormal_inflammatory_respons1.68716371
40MP0006082_CNS_inflammation1.62347818
41MP0000490_abnormal_crypts_of1.60773889
42MP0004947_skin_inflammation1.60670360
43MP0003866_abnormal_defecation1.44558533
44MP0000703_abnormal_thymus_morphology1.42395945
45MP0003300_gastrointestinal_ulcer1.36764038
46MP0004510_myositis1.32573997
47MP0009278_abnormal_bone_marrow1.31366481
48MP0008057_abnormal_DNA_replication1.31308317
49MP0002139_abnormal_hepatobiliary_system1.30393853
50MP0000858_altered_metastatic_potential1.30176648
51MP0003075_altered_response_to1.28852456
52MP0002095_abnormal_skin_pigmentation1.27970872
53MP0008469_abnormal_protein_level1.27928943
54MP0005058_abnormal_lysosome_morphology1.26280026
55MP0001533_abnormal_skeleton_physiology1.25529561
56MP0005167_abnormal_blood-brain_barrier1.24017865
57MP0008004_abnormal_stomach_pH1.23571416
58MP0005310_abnormal_salivary_gland1.23275017
59MP0000343_altered_response_to1.20730358
60MP0003693_abnormal_embryo_hatching1.20229326
61MP0005075_abnormal_melanosome_morpholog1.17312764
62MP0008007_abnormal_cellular_replicative1.16238622
63MP0003448_altered_tumor_morphology1.15318919
64MP0009764_decreased_sensitivity_to1.14428981
65MP0010094_abnormal_chromosome_stability1.14090497
66MP0002933_joint_inflammation1.12853560
67MP0005451_abnormal_body_composition1.10970832
68MP0005166_decreased_susceptibility_to1.08092949
69MP0003195_calcinosis1.07802848
70MP0006054_spinal_hemorrhage1.06014677
71MP0003806_abnormal_nucleotide_metabolis1.05985419
72MP0002138_abnormal_hepatobiliary_system1.03744965
73MP0009840_abnormal_foam_cell1.02289044
74MP0002019_abnormal_tumor_incidence1.00986502
75MP0002254_reproductive_system_inflammat1.00239032
76MP0000604_amyloidosis0.99732203
77MP0002009_preneoplasia0.99157724
78MP0003656_abnormal_erythrocyte_physiolo0.97950158
79MP0000015_abnormal_ear_pigmentation0.97854605
80MP0003828_pulmonary_edema0.96463019
81MP0002332_abnormal_exercise_endurance0.94896765
82MP0003077_abnormal_cell_cycle0.94154567
83MP0003191_abnormal_cellular_cholesterol0.92330578
84MP0001851_eye_inflammation0.91354896
85MP0002277_abnormal_respiratory_mucosa0.87626751
86MP0002998_abnormal_bone_remodeling0.87558656
87MP0003172_abnormal_lysosome_physiology0.85874244
88MP0004381_abnormal_hair_follicle0.85741434
89MP0009765_abnormal_xenobiotic_induced0.83735623
90MP0004782_abnormal_surfactant_physiolog0.81876844
91MP0002132_abnormal_respiratory_system0.81147467
92MP0001501_abnormal_sleep_pattern0.79534261
93MP0002136_abnormal_kidney_physiology0.79423360
94MP0005164_abnormal_response_to0.78549129
95MP0010307_abnormal_tumor_latency0.78430618
96MP0001216_abnormal_epidermal_layer0.78139419
97MP0003690_abnormal_glial_cell0.74677675
98MP0003943_abnormal_hepatobiliary_system0.74526937
99MP0002877_abnormal_melanocyte_morpholog0.73622719
100MP0009763_increased_sensitivity_to0.73561125
101MP0000383_abnormal_hair_follicle0.73233623
102MP0003183_abnormal_peptide_metabolism0.72907691
103MP0000569_abnormal_digit_pigmentation0.71768931
104MP0003045_fibrosis0.71363709
105MP0001191_abnormal_skin_condition0.69928038
106MP0010352_gastrointestinal_tract_polyps0.68212355
107MP0008058_abnormal_DNA_repair0.68014677
108MP0003186_abnormal_redox_activity0.67875447
109MP0004147_increased_porphyrin_level0.67866190
110MP0003795_abnormal_bone_structure0.67387216
111MP0001663_abnormal_digestive_system0.67240563
112MP0002693_abnormal_pancreas_physiology0.66782889
113MP0003646_muscle_fatigue0.66760442
114MP0004883_abnormal_blood_vessel0.66471155
115MP0003453_abnormal_keratinocyte_physiol0.65527066
116MP0005390_skeleton_phenotype0.63391041
117MP0005409_darkened_coat_color0.63236941
118MP0000371_diluted_coat_color0.63154241
119MP0002163_abnormal_gland_morphology0.62069368
120MP0003111_abnormal_nucleus_morphology0.61473374
121MP0002075_abnormal_coat/hair_pigmentati0.60726033
122MP0000249_abnormal_blood_vessel0.60070968
123MP0000313_abnormal_cell_death0.59635077
124MP0000609_abnormal_liver_physiology0.55655420
125MP0005647_abnormal_sex_gland0.54508073
126MP0001919_abnormal_reproductive_system0.54147424
127MP0005165_increased_susceptibility_to0.53478155

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.06531065
2Myositis (HP:0100614)4.73820819
3Recurrent bacterial skin infections (HP:0005406)4.55113763
4Eczematoid dermatitis (HP:0000976)4.45580752
5Elevated erythrocyte sedimentation rate (HP:0003565)4.42122821
6IgM deficiency (HP:0002850)4.11986628
7Thrombocytosis (HP:0001894)3.94881963
8Abnormality of liposaccharide metabolism (HP:0010968)3.88926911
9Abnormality of glycosphingolipid metabolism (HP:0004343)3.88926911
10Abnormality of glycolipid metabolism (HP:0010969)3.88926911
11Optic neuritis (HP:0100653)3.80826019
12Retrobulbar optic neuritis (HP:0100654)3.80826019
13Orchitis (HP:0100796)3.78688332
14Increased IgM level (HP:0003496)3.68046411
15Recurrent fungal infections (HP:0002841)3.62890393
16Chronic otitis media (HP:0000389)3.58811934
17Recurrent viral infections (HP:0004429)3.56047448
18Meningitis (HP:0001287)3.43868169
19Petechiae (HP:0000967)3.32366898
20Mediastinal lymphadenopathy (HP:0100721)3.28762028
21Panhypogammaglobulinemia (HP:0003139)3.20304425
22Chronic obstructive pulmonary disease (HP:0006510)3.15716497
23Obstructive lung disease (HP:0006536)3.15716497
24Agammaglobulinemia (HP:0004432)3.15665901
25Vasculitis (HP:0002633)3.13832145
26Vacuolated lymphocytes (HP:0001922)3.13354311
27Cellulitis (HP:0100658)3.12335339
28Recurrent skin infections (HP:0001581)3.08639618
29Recurrent bronchitis (HP:0002837)3.05847756
30Abnormality of the prostate (HP:0008775)3.00697888
31Abnormality of macrophages (HP:0004311)2.99254187
32B lymphocytopenia (HP:0010976)2.95558358
33Abnormality of B cell number (HP:0010975)2.95558358
34Abnormal delayed hypersensitivity skin test (HP:0002963)2.94822296
35Reticulocytopenia (HP:0001896)2.87633109
36Abnormality of T cell physiology (HP:0011840)2.84745311
37Hematochezia (HP:0002573)2.83930773
38Increased cerebral lipofuscin (HP:0011813)2.83050247
39Stomatitis (HP:0010280)2.82870059
40Joint swelling (HP:0001386)2.80117779
41Recurrent cutaneous fungal infections (HP:0011370)2.80054826
42Chronic mucocutaneous candidiasis (HP:0002728)2.80054826
43Thyroiditis (HP:0100646)2.79282372
44IgG deficiency (HP:0004315)2.78080024
45Abnormality of T cells (HP:0002843)2.77320955
46Autoimmune thrombocytopenia (HP:0001973)2.77026792
47Prolonged bleeding time (HP:0003010)2.69026688
48Inflammation of the large intestine (HP:0002037)2.69026339
49Loss of speech (HP:0002371)2.68735439
50Encephalitis (HP:0002383)2.67560116
51Arterial thrombosis (HP:0004420)2.63517126
52Granulocytopenia (HP:0001913)2.63437802
53Lymphopenia (HP:0001888)2.63152944
54Pustule (HP:0200039)2.61603474
55Periodontitis (HP:0000704)2.59277723
56Keratoconjunctivitis sicca (HP:0001097)2.59163927
57Pulmonary infiltrates (HP:0002113)2.59038657
58Gastrointestinal inflammation (HP:0004386)2.56428735
59Eosinophilia (HP:0001880)2.56028024
60Dysostosis multiplex (HP:0000943)2.55855341
61Abnormality of cells of the lymphoid lineage (HP:0012140)2.55488324
62Recurrent gram-negative bacterial infections (HP:0005420)2.54368122
63Leukocytosis (HP:0001974)2.54061724
64Acute myeloid leukemia (HP:0004808)2.53645227
65Anorexia (HP:0002039)2.51192769
66Gastrointestinal stroma tumor (HP:0100723)2.50674152
67Abnormality of cells of the erythroid lineage (HP:0012130)2.50585050
68Systemic lupus erythematosus (HP:0002725)2.48876670
69Disinhibition (HP:0000734)2.48041148
70Abnormal number of erythroid precursors (HP:0012131)2.47866682
71Polyneuropathy (HP:0001271)2.47596971
72Abnormality of the pleura (HP:0002103)2.45919542
73Increased neuronal autofluorescent lipopigment (HP:0002074)2.44572146
74Chronic diarrhea (HP:0002028)2.44267214
75Severe combined immunodeficiency (HP:0004430)2.43490338
76Impaired platelet aggregation (HP:0003540)2.42694087
77Abnormal platelet function (HP:0011869)2.42694087
78Keratoconjunctivitis (HP:0001096)2.42127197
79Aplastic anemia (HP:0001915)2.41520241
80Abnormality of T cell number (HP:0011839)2.39591938
81Recurrent pneumonia (HP:0006532)2.38494803
82T lymphocytopenia (HP:0005403)2.36950281
83Pulmonary embolism (HP:0002204)2.36700761
84Hemoptysis (HP:0002105)2.35728161
85IgA deficiency (HP:0002720)2.35260641
86Abnormality of eosinophils (HP:0001879)2.33783791
87Epistaxis (HP:0000421)2.32889869
88Nasal polyposis (HP:0100582)2.32826130
89Increased IgE level (HP:0003212)2.31883854
90Increased serum ferritin (HP:0003281)2.31538353
91Autoimmune hemolytic anemia (HP:0001890)2.29690731
92Gingivitis (HP:0000230)2.29173059
93Gangrene (HP:0100758)2.28192886
94Osteomyelitis (HP:0002754)2.27898052
95Abnormality of the fingertips (HP:0001211)2.27461045
96Recurrent sinusitis (HP:0011108)2.26333233
97Amaurosis fugax (HP:0100576)2.25940454
98Combined immunodeficiency (HP:0005387)2.25283092
99Spontaneous hematomas (HP:0007420)2.23801337
100Interstitial pulmonary disease (HP:0006530)2.23717506
101Recurrent lower respiratory tract infections (HP:0002783)2.22616105
102Prostate neoplasm (HP:0100787)2.19151323
103Colitis (HP:0002583)2.16698668
104Sepsis (HP:0100806)2.16406778
105Hypergammaglobulinemia (HP:0010702)2.15201645
106Keratitis (HP:0000491)2.14957044
107Arthralgia (HP:0002829)2.12966866
108Abnormality of the nasal mucosa (HP:0000433)2.11877478
109Lymphoma (HP:0002665)2.11479871
110Urticaria (HP:0001025)2.09558715
111Skin ulcer (HP:0200042)2.08835550
112Gastrointestinal infarctions (HP:0005244)2.08694504
113Chest pain (HP:0100749)2.06371837
114Gingival bleeding (HP:0000225)2.06064689
115Parakeratosis (HP:0001036)2.04282338
116Glomerulopathy (HP:0100820)2.03648174
117Abnormality of iron homeostasis (HP:0011031)2.02256809
118Reduced antithrombin III activity (HP:0001976)2.01093801
119Restrictive lung disease (HP:0002091)2.00871165
120Agnosia (HP:0010524)1.97813392
121Vertigo (HP:0002321)1.96546080
122Alveolar cell carcinoma (HP:0006519)1.94602879
123Chronic sinusitis (HP:0011109)1.94076595
124Pallor (HP:0000980)1.94003529
125Episodic fever (HP:0001954)1.93250615
126Basal ganglia calcification (HP:0002135)1.91407013
127Stomach cancer (HP:0012126)1.90544499
128Albinism (HP:0001022)1.87547823

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.17969492
2TXK3.55865624
3KIT3.01222405
4IRAK42.99636522
5BLK2.76577446
6MAP3K142.75744376
7TEC2.59879950
8BTK2.47183448
9GRK72.28469118
10ZAP702.24655379
11TYK22.23690796
12JAK32.18493407
13IKBKE2.14981171
14TBK12.09388022
15TAOK21.99712518
16IRAK31.97201239
17FLT31.95781145
18IKBKB1.94511456
19SYK1.79128855
20NME21.74792557
21TAOK31.64569046
22CSF1R1.62982752
23PRPF4B1.62128464
24STK101.56916626
25RIPK41.49661955
26FGR1.49499277
27MST41.49490706
28TGFBR21.48072731
29MAP2K31.42305310
30PIM11.41095964
31PIM21.41053780
32ITK1.38371874
33MAP3K111.34414251
34LYN1.31968560
35TAOK11.30147808
36RPS6KA41.30072272
37NEK91.26252947
38LCK1.25424460
39HCK1.20031537
40JAK11.16336941
41LRRK21.13827906
42MAP3K131.13315544
43MUSK1.12242648
44CAMKK21.09382618
45TGFBR11.08129861
46NLK1.07985297
47DDR21.07539344
48CHUK1.06205547
49MARK31.06160100
50TNK21.02097253
51STK160.98465372
52MATK0.94688150
53EEF2K0.93556368
54TLK10.92071564
55CLK10.90542646
56CSK0.86765023
57CDK80.86452631
58ERN10.86345127
59VRK10.86267726
60MAP2K60.83255580
61TRPM70.82142848
62SIK30.82106179
63FGFR30.81658819
64FES0.80773625
65STK40.79495819
66MOS0.76670984
67IRAK20.76572104
68MAP3K10.76372900
69MAP3K120.76086642
70MAP3K30.71420452
71EIF2AK20.71233150
72RPS6KB20.70846787
73PKN20.70059279
74STK240.69834520
75GRK60.69505666
76ACVR1B0.67036658
77FRK0.66523041
78CDC42BPA0.66261072
79MAP3K50.65658364
80RIPK10.63068393
81CDK40.62752032
82JAK20.61591293
83MKNK10.61293141
84ATR0.60501453
85CDK60.57697730
86TYRO30.56676648
87DYRK30.56643982
88NEK20.56535749
89BRD40.56181759
90MAPKAPK30.55300924
91WEE10.54404891
92KDR0.53886425
93PIK3CG0.52526471
94PRKG20.52208090
95MAPK110.51746553
96PLK40.50167578
97SIK20.48644492
98MKNK20.47812213
99HIPK20.46074168
100MAPKAPK20.45733513
101IRAK10.45373939
102EPHA30.45290398
103BMPR20.44297919
104CDK90.44282305
105ABL10.44148175
106RPS6KA60.43695255
107PDK10.42883233
108ADRBK20.42141547
109PRKCD0.41753026
110MAPK40.40343791
111PRKCQ0.40233190
112BRSK20.39706110
113MAPK70.39049973
114YES10.37636439
115TIE10.37432503
116EIF2AK30.36512625
117MAP3K100.35983719
118PASK0.35524456
119BUB10.35495679
120FGFR40.34823090
121INSR0.34448710
122MAP3K80.34439818
123MAP3K60.34086245
124PIK3CA0.33903013
125EGFR0.33549908
126FYN0.29064727
127NUAK10.28120113
128CAMKK10.24575055
129MELK0.22898173
130IGF1R0.19259880
131RPS6KC10.17119184
132RPS6KL10.17119184
133TESK20.16486528

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.37537595
2Leishmaniasis_Homo sapiens_hsa051402.68429983
3DNA replication_Homo sapiens_hsa030302.58497611
4Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.49188941
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.42302404
6Ribosome_Homo sapiens_hsa030102.41652549
7Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.41014475
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.31731145
9Antigen processing and presentation_Homo sapiens_hsa046122.23650543
10Graft-versus-host disease_Homo sapiens_hsa053322.19682133
11Measles_Homo sapiens_hsa051622.16707468
12Hematopoietic cell lineage_Homo sapiens_hsa046402.04119558
13B cell receptor signaling pathway_Homo sapiens_hsa046622.03502872
14Osteoclast differentiation_Homo sapiens_hsa043802.03147753
15Mismatch repair_Homo sapiens_hsa034302.01458271
16Allograft rejection_Homo sapiens_hsa053301.99011928
17Base excision repair_Homo sapiens_hsa034101.88541181
18Herpes simplex infection_Homo sapiens_hsa051681.82757336
19Other glycan degradation_Homo sapiens_hsa005111.80184914
20Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.78630764
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.76826892
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.76621077
23Legionellosis_Homo sapiens_hsa051341.66461455
24Jak-STAT signaling pathway_Homo sapiens_hsa046301.65001852
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.62350099
26Homologous recombination_Homo sapiens_hsa034401.52236844
27Asthma_Homo sapiens_hsa053101.47266130
28Pertussis_Homo sapiens_hsa051331.42827394
29Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.38252562
30Influenza A_Homo sapiens_hsa051641.37925346
31Malaria_Homo sapiens_hsa051441.37559930
32Non-homologous end-joining_Homo sapiens_hsa034501.36556037
33Toxoplasmosis_Homo sapiens_hsa051451.36317854
34Tuberculosis_Homo sapiens_hsa051521.30587248
35Staphylococcus aureus infection_Homo sapiens_hsa051501.28847923
36T cell receptor signaling pathway_Homo sapiens_hsa046601.27850265
37Transcriptional misregulation in cancer_Homo sapiens_hsa052021.26447024
38Shigellosis_Homo sapiens_hsa051311.22913815
39Apoptosis_Homo sapiens_hsa042101.15606099
40TNF signaling pathway_Homo sapiens_hsa046681.14125704
41Glycosaminoglycan degradation_Homo sapiens_hsa005311.12441432
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.10725636
43Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.07012504
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05832292
45Hepatitis B_Homo sapiens_hsa051611.03927576
46Nucleotide excision repair_Homo sapiens_hsa034201.03419878
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.01842967
48p53 signaling pathway_Homo sapiens_hsa041151.00928107
49Acute myeloid leukemia_Homo sapiens_hsa052211.00903761
50Chemokine signaling pathway_Homo sapiens_hsa040620.97333871
51Salmonella infection_Homo sapiens_hsa051320.96481376
52Platelet activation_Homo sapiens_hsa046110.96443038
53Autoimmune thyroid disease_Homo sapiens_hsa053200.95860701
54Viral myocarditis_Homo sapiens_hsa054160.94904036
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.93907521
56Lysosome_Homo sapiens_hsa041420.92029062
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.88409224
58Fanconi anemia pathway_Homo sapiens_hsa034600.87922427
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85473519
60Pyrimidine metabolism_Homo sapiens_hsa002400.85416287
61Rheumatoid arthritis_Homo sapiens_hsa053230.81418679
62Epstein-Barr virus infection_Homo sapiens_hsa051690.81096024
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.78541245
64Spliceosome_Homo sapiens_hsa030400.77144266
65RNA polymerase_Homo sapiens_hsa030200.72825816
66Cell cycle_Homo sapiens_hsa041100.72209978
67HTLV-I infection_Homo sapiens_hsa051660.72051924
68Hepatitis C_Homo sapiens_hsa051600.71702350
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71183382
70Small cell lung cancer_Homo sapiens_hsa052220.70636899
71RNA degradation_Homo sapiens_hsa030180.69775478
72Chronic myeloid leukemia_Homo sapiens_hsa052200.68917529
73Pancreatic cancer_Homo sapiens_hsa052120.65094449
74AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64857710
75Caffeine metabolism_Homo sapiens_hsa002320.63514269
76Type I diabetes mellitus_Homo sapiens_hsa049400.60502882
77Viral carcinogenesis_Homo sapiens_hsa052030.60192198
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59780086
79Protein export_Homo sapiens_hsa030600.59690190
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58675796
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57025750
82Proteasome_Homo sapiens_hsa030500.56901075
83Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.54916714
84Phagosome_Homo sapiens_hsa041450.54537995
85Adipocytokine signaling pathway_Homo sapiens_hsa049200.53797626
86African trypanosomiasis_Homo sapiens_hsa051430.51197008
87Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44652755
88Basal transcription factors_Homo sapiens_hsa030220.42692096
89Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.42169785
90Prolactin signaling pathway_Homo sapiens_hsa049170.40974445
91Sphingolipid signaling pathway_Homo sapiens_hsa040710.39802231
92Arachidonic acid metabolism_Homo sapiens_hsa005900.39535517
93Pentose phosphate pathway_Homo sapiens_hsa000300.38326655
94Thyroid cancer_Homo sapiens_hsa052160.37871929
95Renin-angiotensin system_Homo sapiens_hsa046140.36486344
96VEGF signaling pathway_Homo sapiens_hsa043700.36305524
97N-Glycan biosynthesis_Homo sapiens_hsa005100.35931960
98Sphingolipid metabolism_Homo sapiens_hsa006000.35482500
99Purine metabolism_Homo sapiens_hsa002300.35379882
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.35270496
101Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34011231
102Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33730293
103Systemic lupus erythematosus_Homo sapiens_hsa053220.33468375
104Neurotrophin signaling pathway_Homo sapiens_hsa047220.32741949
105Dorso-ventral axis formation_Homo sapiens_hsa043200.32156135
106Amoebiasis_Homo sapiens_hsa051460.31437277
107Prion diseases_Homo sapiens_hsa050200.30788481
108Type II diabetes mellitus_Homo sapiens_hsa049300.30358785
109HIF-1 signaling pathway_Homo sapiens_hsa040660.29382295
110Sulfur relay system_Homo sapiens_hsa041220.28332110
111Notch signaling pathway_Homo sapiens_hsa043300.27324535
112Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.24620586
113FoxO signaling pathway_Homo sapiens_hsa040680.23872526
114MAPK signaling pathway_Homo sapiens_hsa040100.22159070
115Collecting duct acid secretion_Homo sapiens_hsa049660.21962845
116Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.21851195
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.20274152
118Non-small cell lung cancer_Homo sapiens_hsa052230.16600863
119Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.15908495
120alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.15562330
121Bladder cancer_Homo sapiens_hsa052190.15491531
122Insulin resistance_Homo sapiens_hsa049310.14305117
123Tryptophan metabolism_Homo sapiens_hsa003800.12858887
124Sulfur metabolism_Homo sapiens_hsa009200.11846044
125Complement and coagulation cascades_Homo sapiens_hsa046100.08647284
126Renal cell carcinoma_Homo sapiens_hsa052110.06487169
127Endocytosis_Homo sapiens_hsa041440.06255827
128mTOR signaling pathway_Homo sapiens_hsa041500.02388658
129Carbohydrate digestion and absorption_Homo sapiens_hsa049730.01908029
130Prostate cancer_Homo sapiens_hsa052150.00829730

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