TNKS1BP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.25294352
2regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.22603950
3protein heterotrimerization (GO:0070208)4.04296293
4regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.99062729
5hemidesmosome assembly (GO:0031581)3.90505464
6COPI coating of Golgi vesicle (GO:0048205)3.84734459
7Golgi transport vesicle coating (GO:0048200)3.84734459
8dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.82833460
9negative regulation of fibrinolysis (GO:0051918)3.81580588
10skin morphogenesis (GO:0043589)3.79307618
11semaphorin-plexin signaling pathway (GO:0071526)3.69329616
12plasma membrane repair (GO:0001778)3.69061950
13collagen fibril organization (GO:0030199)3.67926666
14atrioventricular valve morphogenesis (GO:0003181)3.63846373
15cell adhesion mediated by integrin (GO:0033627)3.62867737
16regulation of water loss via skin (GO:0033561)3.59173547
17positive regulation of fatty acid beta-oxidation (GO:0032000)3.58439241
18endodermal cell differentiation (GO:0035987)3.55395697
19endothelial cell chemotaxis (GO:0035767)3.48970226
20cell-substrate junction assembly (GO:0007044)3.46364594
21negative regulation of fatty acid transport (GO:2000192)3.45366043
22regulation of fatty acid beta-oxidation (GO:0031998)3.42534113
23low-density lipoprotein particle clearance (GO:0034383)3.42455057
24apoptotic cell clearance (GO:0043277)3.41064730
25epithelial cell-cell adhesion (GO:0090136)3.39665883
26chondrocyte proliferation (GO:0035988)3.39477057
27surfactant homeostasis (GO:0043129)3.38508320
28negative regulation of chondrocyte differentiation (GO:0032331)3.31956594
29maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.28245731
30protein retention in ER lumen (GO:0006621)3.21828023
31cytoskeletal anchoring at plasma membrane (GO:0007016)3.21386623
32Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.20668327
33establishment of skin barrier (GO:0061436)3.19158887
34axon extension involved in axon guidance (GO:0048846)3.16391421
35neuron projection extension involved in neuron projection guidance (GO:1902284)3.16391421
36regulation of cholesterol homeostasis (GO:2000188)3.11011944
37alpha-linolenic acid metabolic process (GO:0036109)3.08233751
38insulin-like growth factor receptor signaling pathway (GO:0048009)3.07001847
39regulation of establishment of planar polarity (GO:0090175)3.04477711
40epoxygenase P450 pathway (GO:0019373)3.04224036
41cell migration involved in sprouting angiogenesis (GO:0002042)3.03445284
42adherens junction assembly (GO:0034333)3.00604734
43basement membrane organization (GO:0071711)3.00141681
44establishment of apical/basal cell polarity (GO:0035089)2.99129483
45positive regulation of fatty acid oxidation (GO:0046321)2.97018087
46vascular endothelial growth factor signaling pathway (GO:0038084)2.96477577
47positive regulation of endothelial cell apoptotic process (GO:2000353)2.94896226
48regulation of fibrinolysis (GO:0051917)2.94822334
49regulation of plasminogen activation (GO:0010755)2.93561697
50stress fiber assembly (GO:0043149)2.90759340
51gap junction assembly (GO:0016264)2.87751081
52regulation of glucose import in response to insulin stimulus (GO:2001273)2.86705956
53paraxial mesoderm development (GO:0048339)2.86088363
54regulation of tight junction assembly (GO:2000810)2.84703373
55blood vessel endothelial cell migration (GO:0043534)2.81420618
56branching involved in mammary gland duct morphogenesis (GO:0060444)2.80285242
57branching involved in salivary gland morphogenesis (GO:0060445)2.77990282
58vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.77934976
59protein localization to endosome (GO:0036010)2.76767989
60convergent extension (GO:0060026)2.74449794
61collagen metabolic process (GO:0032963)2.73522561
62hippo signaling (GO:0035329)2.73012021
63retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.70054014
64multicellular organismal macromolecule metabolic process (GO:0044259)2.69627772
65multicellular organismal water homeostasis (GO:0050891)2.69350925
66non-canonical Wnt signaling pathway (GO:0035567)2.68771754
67focal adhesion assembly (GO:0048041)2.67177508
68cell-substrate adherens junction assembly (GO:0007045)2.67177508
69barbed-end actin filament capping (GO:0051016)2.65648822
70chemical homeostasis within a tissue (GO:0048875)2.65320406
71regulation of fatty acid oxidation (GO:0046320)2.65013867
72collagen catabolic process (GO:0030574)2.64917656
73retina vasculature morphogenesis in camera-type eye (GO:0061299)2.64654594
74negative regulation of keratinocyte proliferation (GO:0010839)2.64011062
75establishment of planar polarity (GO:0001736)2.62861285
76establishment of tissue polarity (GO:0007164)2.62861285
77regulation of hippo signaling (GO:0035330)2.62763641
78cell junction assembly (GO:0034329)2.62540147
794-hydroxyproline metabolic process (GO:0019471)2.62309170
80multicellular organismal metabolic process (GO:0044236)2.61861028
81extracellular matrix assembly (GO:0085029)2.61820319
82epithelial cell differentiation involved in prostate gland development (GO:0060742)2.61077196
83negative regulation of cartilage development (GO:0061037)2.59405263
84sulfur amino acid catabolic process (GO:0000098)2.58450362
85bone trabecula formation (GO:0060346)2.58414389
86extracellular matrix disassembly (GO:0022617)2.57611811
87cell migration involved in heart development (GO:0060973)2.57594968
88positive regulation of p38MAPK cascade (GO:1900745)2.57036410
89desmosome organization (GO:0002934)2.56430435
90multicellular organismal catabolic process (GO:0044243)2.56384633
91negative regulation of cell size (GO:0045792)2.56048575
92growth hormone receptor signaling pathway (GO:0060396)2.55337084
93regulation of endothelial cell chemotaxis (GO:2001026)2.55324307
94positive regulation of glycogen biosynthetic process (GO:0045725)2.55182537
95bundle of His cell to Purkinje myocyte communication (GO:0086069)2.54350085
96negative regulation of cell fate specification (GO:0009996)2.53704122
97adherens junction organization (GO:0034332)2.53604276
98type B pancreatic cell proliferation (GO:0044342)2.52383491
99positive regulation of lipid catabolic process (GO:0050996)2.51771964
100negative regulation of lipid transport (GO:0032369)2.50825351
101renal filtration (GO:0097205)2.50096061
102peptidyl-glutamic acid carboxylation (GO:0017187)2.49899018
103protein carboxylation (GO:0018214)2.49899018
104cell junction organization (GO:0034330)2.49374246
105regulation of p38MAPK cascade (GO:1900744)2.48598095
106keratinocyte proliferation (GO:0043616)2.47920058
107protein localization to cell surface (GO:0034394)2.46760767
108regulation of cardioblast differentiation (GO:0051890)2.46353808
109cochlea morphogenesis (GO:0090103)2.46004846
110regulation of early endosome to late endosome transport (GO:2000641)2.45780046
111cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.45664663
112triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.45569107
113lysine catabolic process (GO:0006554)2.45213939
114lysine metabolic process (GO:0006553)2.45213939
115endocardial cushion development (GO:0003197)2.44709649
116positive regulation of osteoblast proliferation (GO:0033690)2.44167485
117wound healing, spreading of epidermal cells (GO:0035313)2.44057759
118negative regulation of smooth muscle cell migration (GO:0014912)2.42462446
119glomerular basement membrane development (GO:0032836)2.42391086
120mesodermal cell differentiation (GO:0048333)2.40932827
121regulation of extracellular matrix disassembly (GO:0010715)2.40748956
122negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.40223137
123peptidyl-proline hydroxylation (GO:0019511)2.40120487
124maternal placenta development (GO:0001893)2.39468316
125fatty acid transmembrane transport (GO:1902001)2.37169017
126endothelial cell morphogenesis (GO:0001886)2.36836856
127positive regulation of fatty acid metabolic process (GO:0045923)2.36607330
128cellular response to vitamin (GO:0071295)2.35687452
129plasma lipoprotein particle clearance (GO:0034381)2.35355757
130endocytic recycling (GO:0032456)2.34596547
131complement activation, alternative pathway (GO:0006957)2.34207328
132extracellular matrix organization (GO:0030198)2.34139934
133fibrinolysis (GO:0042730)2.33322899
134extracellular structure organization (GO:0043062)2.33215608
135cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.33005311
136protein hydroxylation (GO:0018126)2.31808272
137establishment or maintenance of monopolar cell polarity (GO:0061339)2.30945515
138establishment of monopolar cell polarity (GO:0061162)2.30945515
139sequestering of extracellular ligand from receptor (GO:0035581)2.30555246
140polarized epithelial cell differentiation (GO:0030859)2.27575424
141positive regulation of blood vessel endothelial cell migration (GO:0043536)2.26942839
142regulation of cholesterol storage (GO:0010885)2.26682160
143positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.24429401
144positive regulation of glycogen metabolic process (GO:0070875)2.24018464
145carnitine shuttle (GO:0006853)2.23578336
146positive regulation of histone deacetylation (GO:0031065)2.22866235
147regulation of protein activation cascade (GO:2000257)2.21867058
148planar cell polarity pathway involved in neural tube closure (GO:0090179)2.20910871
149cellular response to growth hormone stimulus (GO:0071378)2.20308511
150midgut development (GO:0007494)2.20026864
151negative regulation of catenin import into nucleus (GO:0035414)2.19810438
152regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.19572029
153activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.18759280
154homocysteine metabolic process (GO:0050667)2.18722054
155regulation of membrane protein ectodomain proteolysis (GO:0051043)2.18542312
156white fat cell differentiation (GO:0050872)2.17546573
157regulation of complement activation (GO:0030449)2.17492038

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.25248744
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.91582429
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.77337383
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.55771763
5TRIM28_21343339_ChIP-Seq_HEK293_Human3.39280637
6CLOCK_20551151_ChIP-Seq_293T_Human3.07612228
7RXR_22158963_ChIP-Seq_LIVER_Mouse2.87198833
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.77506119
9PPARA_22158963_ChIP-Seq_LIVER_Mouse2.59888927
10* LXR_22158963_ChIP-Seq_LIVER_Mouse2.51434050
11TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.38360186
12ESR2_21235772_ChIP-Seq_MCF-7_Human2.24022841
13NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.16926100
14ZNF263_19887448_ChIP-Seq_K562_Human2.10432229
15TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.04502030
16TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.98239911
17RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.95922291
18PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.84230474
19TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.84169567
20ESR1_21235772_ChIP-Seq_MCF-7_Human1.79724780
21TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.74092307
22ERG_21242973_ChIP-ChIP_JURKAT_Human1.70949837
23ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.70770943
24WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.68428587
25* ELK3_25401928_ChIP-Seq_HUVEC_Human1.66191273
26PPAR_26484153_Chip-Seq_NCI-H1993_Human1.65689656
27STAT6_21828071_ChIP-Seq_BEAS2B_Human1.60613898
28FOXO3_23340844_ChIP-Seq_DLD1_Human1.58863842
29* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.58384413
30* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.57287674
31* RACK7_27058665_Chip-Seq_MCF-7_Human1.56071258
32STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.55681201
33* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.55599279
34FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.54917180
35* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.54691455
36* LXR_22292898_ChIP-Seq_THP-1_Human1.53355253
37HIF1A_21447827_ChIP-Seq_MCF-7_Human1.52784778
38EP300_21415370_ChIP-Seq_HL-1_Mouse1.52339606
39ESR1_20079471_ChIP-ChIP_T-47D_Human1.50056405
40EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.48693307
41* ATF3_27146783_Chip-Seq_COLON_Human1.47524513
42KDM2B_26808549_Chip-Seq_K562_Human1.44358276
43SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.43785673
44CJUN_26792858_Chip-Seq_BT549_Human1.41323904
45SOX9_24532713_ChIP-Seq_HFSC_Mouse1.41168830
46ZFP281_18757296_ChIP-ChIP_E14_Mouse1.39912582
47TBX20_22328084_ChIP-Seq_HEART_Mouse1.38798672
48TBX20_22080862_ChIP-Seq_HEART_Mouse1.38798672
49EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.38138702
50THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.37875812
51TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35370086
52TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.32637546
53TCF7_22412390_ChIP-Seq_EML_Mouse1.30609742
54POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.30358858
55* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.29777117
56* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.29777117
57ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29016830
58NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.28995484
59KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.28009886
60KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27989723
61KDM2B_26808549_Chip-Seq_DND41_Human1.27371674
62* FOXA2_19822575_ChIP-Seq_HepG2_Human1.25806876
63ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25529438
64SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.22682921
65* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21849251
66RUNX1_27514584_Chip-Seq_MCF-7_Human1.20760720
67SOX2_27498859_Chip-Seq_STOMACH_Mouse1.19432825
68SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.19040210
69KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.18575055
70ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.18036184
71* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.17583800
72DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.14271506
73GATA2_21666600_ChIP-Seq_HMVEC_Human1.12994430
74TET1_21490601_ChIP-Seq_MESCs_Mouse1.12678222
75ZFP281_27345836_Chip-Seq_ESCs_Mouse1.12507699
76EGR1_19374776_ChIP-ChIP_THP-1_Human1.12087094
77SMC4_20622854_ChIP-Seq_HELA_Human1.09435745
78* SOX2_20726797_ChIP-Seq_SW620_Human1.08731877
79BRD4_25478319_ChIP-Seq_HGPS_Human1.08550771
80CTCF_27219007_Chip-Seq_Bcells_Human1.08096968
81SA1_27219007_Chip-Seq_ERYTHROID_Human1.07440750
82P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06722045
83* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.06629248
84ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.05977932
85JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05939501
86KDM2B_26808549_Chip-Seq_JURKAT_Human1.05820336
87CDX2_20551321_ChIP-Seq_CACO-2_Human1.05441287
88MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.05345200
89* CREB1_26743006_Chip-Seq_LNCaP_Human1.04813796
90NRF2_20460467_ChIP-Seq_MEFs_Mouse1.04627966
91NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.04627966
92SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04069651
93BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.03640895
94ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.03368919
95FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.02933953
96NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.02604483
97UBF1/2_26484160_Chip-Seq_HMECs_Human1.02371635
98CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.02356528
99* TP63_22573176_ChIP-Seq_HFKS_Human1.02275245
100CTCF_27219007_Chip-Seq_ERYTHROID_Human1.01414432
101TP53_23651856_ChIP-Seq_MEFs_Mouse1.00923876
102AR_21909140_ChIP-Seq_LNCAP_Human1.00573315
103TP53_22127205_ChIP-Seq_IMR90_Human1.00560405
104TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.99418543
105DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99324059
106SMC1_22415368_ChIP-Seq_MEFs_Mouse0.98241120
107NFIB_24661679_ChIP-Seq_LUNG_Mouse0.97772542
108ISL1_27105846_Chip-Seq_CPCs_Mouse0.96611743
109TP53_16413492_ChIP-PET_HCT116_Human0.96530645
110* KLF5_25053715_ChIP-Seq_YYC3_Human0.96000707
111VDR_21846776_ChIP-Seq_THP-1_Human0.95589241
112TET1_21451524_ChIP-Seq_MESCs_Mouse0.95141425
113RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.94959343
114ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.94365567
115NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94068748
116TP53_20018659_ChIP-ChIP_R1E_Mouse0.93205948
117WT1_25993318_ChIP-Seq_PODOCYTE_Human0.93022491
118KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.91843427
119HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.91754954
120CDX2_19796622_ChIP-Seq_MESCs_Mouse0.91731685
121TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.91531287
122JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.91520694
123SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90216683
124DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90182834
125SALL4_18804426_ChIP-ChIP_XEN_Mouse0.89758742
126DROSHA_22980978_ChIP-Seq_HELA_Human0.89698492
127GATA6_25053715_ChIP-Seq_YYC3_Human0.87518359

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.60911054
2MP0003705_abnormal_hypodermis_morpholog5.01828554
3MP0005275_abnormal_skin_tensile4.35052839
4MP0010234_abnormal_vibrissa_follicle2.66469011
5MP0004272_abnormal_basement_membrane2.59189794
6MP0003566_abnormal_cell_adhesion2.51835989
7MP0003279_aneurysm2.39351828
8MP0005623_abnormal_meninges_morphology2.38975024
9MP0003941_abnormal_skin_development2.35489776
10MP0002139_abnormal_hepatobiliary_system2.34454632
11MP0005503_abnormal_tendon_morphology2.32073297
12MP0005360_urolithiasis2.17437691
13MP0001958_emphysema2.16072561
14MP0000566_synostosis2.13689810
15MP0010352_gastrointestinal_tract_polyps2.12807614
16MP0005409_darkened_coat_color2.04469477
17MP0002060_abnormal_skin_morphology2.01602983
18MP0000762_abnormal_tongue_morphology1.96956772
19MP0003252_abnormal_bile_duct1.94681343
20MP0004185_abnormal_adipocyte_glucose1.72111598
21MP0005023_abnormal_wound_healing1.72073951
22MP0010368_abnormal_lymphatic_system1.68597839
23MP0003091_abnormal_cell_migration1.67346562
24MP0009384_cardiac_valve_regurgitation1.62103633
25MP0005670_abnormal_white_adipose1.61133499
26MP0006054_spinal_hemorrhage1.59202817
27MP0005666_abnormal_adipose_tissue1.58674202
28MP0005365_abnormal_bile_salt1.58364117
29MP0002098_abnormal_vibrissa_morphology1.56808221
30MP0002796_impaired_skin_barrier1.56775021
31MP0000751_myopathy1.56173353
32MP0005085_abnormal_gallbladder_physiolo1.54471975
33MP0003045_fibrosis1.53632265
34MP0004130_abnormal_muscle_cell1.52687910
35MP0003300_gastrointestinal_ulcer1.52253280
36MP0000013_abnormal_adipose_tissue1.49269886
37MP0003283_abnormal_digestive_organ1.46092320
38MP0004264_abnormal_extraembryonic_tissu1.42368858
39MP0010329_abnormal_lipoprotein_level1.42048849
40MP0005375_adipose_tissue_phenotype1.37879521
41MP0002877_abnormal_melanocyte_morpholog1.37252904
42MP0002896_abnormal_bone_mineralization1.34586803
43MP0000733_abnormal_muscle_development1.33423816
44MP0002837_dystrophic_cardiac_calcinosis1.32368307
45MP0009053_abnormal_anal_canal1.31857827
46MP0004782_abnormal_surfactant_physiolog1.29318174
47MP0009780_abnormal_chondrocyte_physiolo1.28930890
48MP0000537_abnormal_urethra_morphology1.27495948
49MP0002295_abnormal_pulmonary_circulatio1.24359955
50MP0001849_ear_inflammation1.24117619
51MP0000003_abnormal_adipose_tissue1.23668029
52MP0005076_abnormal_cell_differentiation1.21844970
53MP0002254_reproductive_system_inflammat1.21346121
54MP0001243_abnormal_dermal_layer1.21255370
55MP0000377_abnormal_hair_follicle1.18274373
56MP0000678_abnormal_parathyroid_gland1.15718384
57MP0010678_abnormal_skin_adnexa1.15005746
58MP0010030_abnormal_orbit_morphology1.13580960
59MP0004087_abnormal_muscle_fiber1.13003979
60MP0004084_abnormal_cardiac_muscle1.12621277
61MP0002168_other_aberrant_phenotype1.12440224
62MP0000750_abnormal_muscle_regeneration1.10703927
63MP0002249_abnormal_larynx_morphology1.09611236
64MP0005508_abnormal_skeleton_morphology1.08803536
65MP0006138_congestive_heart_failure1.07252048
66MP0005257_abnormal_intraocular_pressure1.06878062
67MP0002234_abnormal_pharynx_morphology1.05945987
68MP0003115_abnormal_respiratory_system1.05226790
69MP0000767_abnormal_smooth_muscle1.04920148
70MP0008875_abnormal_xenobiotic_pharmacok1.04643694
71MP0000462_abnormal_digestive_system1.03786864
72MP0009840_abnormal_foam_cell1.02966591
73MP0005501_abnormal_skin_physiology1.02965609
74MP0000467_abnormal_esophagus_morphology1.02796216
75MP0005083_abnormal_biliary_tract1.02762897
76MP0003453_abnormal_keratinocyte_physiol1.02288157
77MP0003191_abnormal_cellular_cholesterol1.00976221
78MP0000579_abnormal_nail_morphology1.00650561
79MP0004858_abnormal_nervous_system0.98424370
80MP0000534_abnormal_ureter_morphology0.96481706
81MP0002108_abnormal_muscle_morphology0.94866229
82MP0001666_abnormal_nutrient_absorption0.94804638
83MP0009931_abnormal_skin_appearance0.94278709
84MP0003385_abnormal_body_wall0.94140927
85MP0000627_abnormal_mammary_gland0.93997199
86MP0001348_abnormal_lacrimal_gland0.93585384
87MP0005330_cardiomyopathy0.92674278
88MP0001299_abnormal_eye_distance/0.89587640
89MP0010630_abnormal_cardiac_muscle0.87954917
90MP0008961_abnormal_basal_metabolism0.87942337
91MP0000383_abnormal_hair_follicle0.87748671
92MP0000428_abnormal_craniofacial_morphol0.85561843
93MP0002118_abnormal_lipid_homeostasis0.83869676
94MP0001542_abnormal_bone_strength0.82795548
95MP0005058_abnormal_lysosome_morphology0.82070102
96MP0010771_integument_phenotype0.81348606
97MP0002128_abnormal_blood_circulation0.81179817
98MP0005451_abnormal_body_composition0.79741293
99MP0000609_abnormal_liver_physiology0.79250435
100MP0000432_abnormal_head_morphology0.79049525
101MP0003950_abnormal_plasma_membrane0.77065227
102MP0003755_abnormal_palate_morphology0.75850671
103MP0002697_abnormal_eye_size0.75443011
104MP0002089_abnormal_postnatal_growth/wei0.75375925
105MP0001879_abnormal_lymphatic_vessel0.74945453
106MP0005595_abnormal_vascular_smooth0.74259253
107MP0002269_muscular_atrophy0.73979171
108MP0000759_abnormal_skeletal_muscle0.71767505
109MP0008004_abnormal_stomach_pH0.71653842
110MP0001614_abnormal_blood_vessel0.71560012
111MP0001544_abnormal_cardiovascular_syste0.68657031
112MP0005385_cardiovascular_system_phenoty0.68657031
113MP0002971_abnormal_brown_adipose0.66773698
114MP0004381_abnormal_hair_follicle0.66768363
115MP0000163_abnormal_cartilage_morphology0.66475239
116MP0001661_extended_life_span0.66396815
117MP0008260_abnormal_autophagy0.66197066
118MP0003942_abnormal_urinary_system0.66154200
119MP0005332_abnormal_amino_acid0.66017541
120MP0000858_altered_metastatic_potential0.65934047
121MP0001216_abnormal_epidermal_layer0.65838975
122MP0002925_abnormal_cardiovascular_devel0.65700246
123MP0009250_abnormal_appendicular_skeleto0.65529644
124MP0000749_muscle_degeneration0.65218344
125MP0001881_abnormal_mammary_gland0.65015586
126MP0004947_skin_inflammation0.64954940
127MP0005248_abnormal_Harderian_gland0.64549465
128MP0003329_amyloid_beta_deposits0.64462017
129MP0002116_abnormal_craniofacial_bone0.64243847
130MP0002282_abnormal_trachea_morphology0.63870809
131MP0004233_abnormal_muscle_weight0.62757193
132MP0000747_muscle_weakness0.62418999
133MP0005197_abnormal_uvea_morphology0.62147558
134MP0002111_abnormal_tail_morphology0.61812813
135MP0002115_abnormal_skeleton_extremities0.61758464

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.94604329
2Premature rupture of membranes (HP:0001788)5.63015589
3Atrophic scars (HP:0001075)4.29420437
4Ankle contracture (HP:0006466)4.14327868
5Shallow orbits (HP:0000586)4.12022062
6Cerebral aneurysm (HP:0004944)3.85711698
7Aortic dissection (HP:0002647)3.70162421
8Increased connective tissue (HP:0009025)3.68512915
9Peritonitis (HP:0002586)3.65830909
10Broad metatarsal (HP:0001783)3.63174662
11Fragile skin (HP:0001030)3.48322947
12Right ventricular cardiomyopathy (HP:0011663)3.42149078
13Mitral valve prolapse (HP:0001634)3.18009941
14Type 1 muscle fiber predominance (HP:0003803)3.13133707
15Abnormality of nail color (HP:0100643)3.08926730
16Deep venous thrombosis (HP:0002625)3.07912990
17Aortic aneurysm (HP:0004942)3.07632681
18Bladder diverticulum (HP:0000015)3.03645405
19Dilatation of the ascending aorta (HP:0005111)2.98145615
20Natal tooth (HP:0000695)2.92987570
21Fragile nails (HP:0001808)2.80561532
22Hyperacusis (HP:0010780)2.80212426
23Advanced eruption of teeth (HP:0006288)2.77484286
24Spinal rigidity (HP:0003306)2.77042781
25Cervical subluxation (HP:0003308)2.75283971
26Mildly elevated creatine phosphokinase (HP:0008180)2.74183959
27Aneurysm (HP:0002617)2.73075743
28Follicular hyperkeratosis (HP:0007502)2.66634227
29Soft skin (HP:0000977)2.63850333
30Genu recurvatum (HP:0002816)2.62287921
31Increased variability in muscle fiber diameter (HP:0003557)2.59943155
32Broad face (HP:0000283)2.52827437
33Neonatal short-limb short stature (HP:0008921)2.50514827
34Blue sclerae (HP:0000592)2.47551493
35Difficulty climbing stairs (HP:0003551)2.46707856
36Upper limb amyotrophy (HP:0009129)2.46146145
37Distal upper limb amyotrophy (HP:0007149)2.46146145
38Pterygium (HP:0001059)2.41161958
39Plantar hyperkeratosis (HP:0007556)2.39814624
40Wrist flexion contracture (HP:0001239)2.32920497
41Onycholysis (HP:0001806)2.32755221
42Obstructive sleep apnea (HP:0002870)2.30658359
43Pili torti (HP:0003777)2.30521468
44Hyporeflexia of lower limbs (HP:0002600)2.28391797
45Lymphangioma (HP:0100764)2.26532050
46Ulnar bowing (HP:0003031)2.26319591
47Distal lower limb muscle weakness (HP:0009053)2.25813009
48Xanthomatosis (HP:0000991)2.25792918
49Thick nail (HP:0001805)2.25345270
50Turricephaly (HP:0000262)2.24915895
51Abnormality of skeletal muscle fiber size (HP:0012084)2.23986184
52Bowel diverticulosis (HP:0005222)2.23724898
53Alopecia of scalp (HP:0002293)2.22454982
54Long toe (HP:0010511)2.22056291
55Wormian bones (HP:0002645)2.21881736
56Selective tooth agenesis (HP:0001592)2.21046161
57Abnormality of the Achilles tendon (HP:0005109)2.20924529
58Abnormality of dentin (HP:0010299)2.20581215
59Ectopia lentis (HP:0001083)2.19823359
60Hyperextensible skin (HP:0000974)2.18784137
61Achilles tendon contracture (HP:0001771)2.16962255
62Milia (HP:0001056)2.16626346
63Myocardial infarction (HP:0001658)2.09670672
64Muscle fiber splitting (HP:0003555)2.09091870
65Camptodactyly of toe (HP:0001836)2.08575251
66Deviation of the hallux (HP:0010051)2.06400966
67Mitral regurgitation (HP:0001653)2.04987029
68Ankyloglossia (HP:0010296)2.04808446
69Abnormality of the distal phalanges of the toes (HP:0010182)2.03752511
70Buphthalmos (HP:0000557)2.01998212
71Slender build (HP:0001533)2.01550274
72Bronchomalacia (HP:0002780)2.00565186
73Hallux valgus (HP:0001822)2.00107392
74Abnormal delivery (HP:0001787)1.98700377
75Scapular winging (HP:0003691)1.97872684
76Nail dystrophy (HP:0008404)1.97842899
77Thin bony cortex (HP:0002753)1.96145767
78Hand muscle atrophy (HP:0009130)1.95741925
79Infantile muscular hypotonia (HP:0008947)1.95232320
80Elbow flexion contracture (HP:0002987)1.94751661
81Bowed forearm bones (HP:0003956)1.94548553
82Bowing of the arm (HP:0006488)1.94548553
83Difficulty running (HP:0009046)1.94178443
84Biconcave vertebral bodies (HP:0004586)1.90922104
85Striae distensae (HP:0001065)1.90693226
86Radial bowing (HP:0002986)1.90476598
87Overgrowth (HP:0001548)1.89003930
88Disproportionate tall stature (HP:0001519)1.88423606
89Back pain (HP:0003418)1.88247277
90Hypoalphalipoproteinemia (HP:0003233)1.87000144
91Enlarged penis (HP:0000040)1.86785819
92Osteolytic defects of the hand bones (HP:0009699)1.86112097
93Osteolytic defects of the phalanges of the hand (HP:0009771)1.86112097
94Short nail (HP:0001799)1.84962533
95Distal lower limb amyotrophy (HP:0008944)1.84586549
96Sparse lateral eyebrow (HP:0005338)1.83514122
97Vascular tortuosity (HP:0004948)1.83362211
98Wide anterior fontanel (HP:0000260)1.82827040
99Venous abnormality (HP:0002624)1.82619631
100Round ear (HP:0100830)1.81086139
101Abnormality of oral frenula (HP:0000190)1.80899357
102Tibial bowing (HP:0002982)1.80564446
103Ridged nail (HP:0001807)1.79345987
104Skin nodule (HP:0200036)1.77691499
105Palmoplantar hyperkeratosis (HP:0000972)1.77457945
106Abnormality of the acetabulum (HP:0003170)1.76429143
107Abnormal hair laboratory examination (HP:0003328)1.76417863
108Trismus (HP:0000211)1.76366411
109Knee flexion contracture (HP:0006380)1.74373473
110Aplasia involving bones of the extremities (HP:0009825)1.73622996
111Aplasia involving bones of the upper limbs (HP:0009823)1.73622996
112Aplasia of the phalanges of the hand (HP:0009802)1.73622996
113Abnormality of the distal phalanx of the thumb (HP:0009617)1.73383471
114Aortic regurgitation (HP:0001659)1.72959148
115Acanthosis nigricans (HP:0000956)1.70864658
116Abnormality of carpal bone ossification (HP:0006257)1.70842037
117Abnormal ossification of hand bones (HP:0005921)1.69200607
118Focal segmental glomerulosclerosis (HP:0000097)1.69090810
119Vertebral compression fractures (HP:0002953)1.69027575
120Coxa vara (HP:0002812)1.68860009
121Increased mean platelet volume (HP:0011877)1.68578758
122Arterial tortuosity (HP:0005116)1.66744678
123Neonatal death (HP:0003811)1.66734740
124Joint laxity (HP:0001388)1.66156976
125Generalized amyotrophy (HP:0003700)1.65706985
126Lower limb amyotrophy (HP:0007210)1.64799169
127Vertebral arch anomaly (HP:0008438)1.64560764
128Venous insufficiency (HP:0005293)1.64153452
129Arnold-Chiari malformation (HP:0002308)1.64142878
130Subacute progressive viral hepatitis (HP:0006572)1.63523366
131Insomnia (HP:0100785)1.63045425
132Hypotrichosis (HP:0001006)1.62850172
133Abnormality of the peritoneum (HP:0002585)1.62828258
134Increased density of long bones (HP:0006392)1.62375429
135Hypoplasia of dental enamel (HP:0006297)1.61886883
136Mitral stenosis (HP:0001718)1.61655983
137Complement deficiency (HP:0004431)1.60855704
138Flat acetabular roof (HP:0003180)1.60838576
139Abnormal cartilage morphology (HP:0002763)1.59877592
140Epidermoid cyst (HP:0200040)1.59166817
141Coronal craniosynostosis (HP:0004440)1.58104818

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.94268529
2TTN3.69888999
3PKN23.48609214
4SIK12.94215266
5DDR22.88194390
6RIPK12.86602572
7ERN12.83443375
8PDGFRA2.81004933
9LATS12.67969766
10SMG12.51549188
11LATS22.20545105
12EPHA22.17406726
13PTK61.98179680
14FER1.81472497
15EEF2K1.81084515
16EPHB21.78828662
17PTK21.68860563
18BMX1.65195365
19CAMK1D1.51112451
20LMTK21.51049696
21FGFR41.50326454
22MAP3K101.49478901
23PAK21.41737389
24DMPK1.33147805
25IRAK31.33071021
26MST1R1.26699314
27MAP3K61.23898490
28LRRK21.23693682
29RPS6KA21.21171869
30PAK31.20629475
31CAMK1G1.20026199
32PAK41.17890299
33EPHB11.15446857
34PRKD31.14068857
35MET1.13533334
36MTOR1.12007894
37PDGFRB1.11130563
38PRPF4B1.09996627
39KSR21.08798181
40RET1.05837779
41FRK1.04209400
42ARAF1.03947584
43FGFR11.03663884
44MAP3K71.02722553
45TGFBR21.02524523
46TAOK11.01847119
47MAP2K10.96932861
48ICK0.94184090
49MAP3K20.93064863
50FGFR20.92788572
51BCKDK0.90803127
52TRPM70.88156494
53PTK2B0.85945507
54PAK60.84519598
55NTRK10.82394063
56EPHA30.81030186
57STK380.78687737
58MAP3K30.76748465
59MYLK0.76342602
60CAMKK10.75432848
61RPS6KB20.75424953
62STK38L0.73965375
63PIK3CA0.73644789
64ILK0.73509129
65TIE10.72853794
66ROCK10.72813794
67JAK10.72206300
68PRKCH0.69599434
69TYRO30.68903987
70PRKD10.68401098
71AKT30.67921176
72FGFR30.67149909
73MAPKAPK30.67053927
74STK30.65408930
75CDK60.63828154
76RPS6KC10.63245483
77RPS6KL10.63245483
78PIM20.63130289
79SCYL20.59512983
80LIMK10.58941172
81PRKD20.57242120
82MAP2K30.56421546
83FLT30.55907991
84CDC42BPA0.54703150
85MAP3K90.53926476
86PDK30.52887658
87PDK40.52887658
88PRKG20.51765875
89DAPK30.50816830
90CDK120.50293017
91MOS0.49978636
92DAPK20.49707704
93ERBB20.48608747
94DYRK1B0.48146026
95ALK0.45987392
96PIK3CG0.45263112
97ERBB40.45030515
98NEK10.43883742
99PDPK10.43244633
100CDK70.43146546
101NME20.43013754
102ROCK20.42867422
103MAP3K130.41921679
104MARK20.41579406
105SRC0.41524658
106RPS6KA60.41481456
107MAP3K10.40244650
108HIPK20.39974243
109PRKAA20.39789099
110NEK90.38799012
111RPS6KA40.38472635
112MAPK70.37221200
113MAP3K80.37188949
114TESK10.35255906
115MAP2K20.33614587
116GSK3A0.33471410
117ABL20.32376992
118KDR0.32085610
119PHKG20.31217139
120MAPK150.30529065
121CAMK2G0.30060164
122MAPKAPK20.29847020
123BRAF0.28741098
124TAOK20.27168624
125CDK90.23889716

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.80187465
2ECM-receptor interaction_Homo sapiens_hsa045122.43615066
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.15624946
4Notch signaling pathway_Homo sapiens_hsa043301.96782214
5Fatty acid degradation_Homo sapiens_hsa000711.95873923
6Arginine biosynthesis_Homo sapiens_hsa002201.91885655
7PPAR signaling pathway_Homo sapiens_hsa033201.91180009
8Focal adhesion_Homo sapiens_hsa045101.90338644
9Primary bile acid biosynthesis_Homo sapiens_hsa001201.88929562
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.84262466
112-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.72955083
12Fatty acid metabolism_Homo sapiens_hsa012121.56728891
13Bladder cancer_Homo sapiens_hsa052191.50973313
14Thyroid cancer_Homo sapiens_hsa052161.49709756
15Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.46673878
16Protein digestion and absorption_Homo sapiens_hsa049741.46622429
17Complement and coagulation cascades_Homo sapiens_hsa046101.45714931
18Amoebiasis_Homo sapiens_hsa051461.45603606
19Bile secretion_Homo sapiens_hsa049761.44898816
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.44792548
21Adherens junction_Homo sapiens_hsa045201.44428364
22Proteoglycans in cancer_Homo sapiens_hsa052051.43839298
23Tryptophan metabolism_Homo sapiens_hsa003801.41289647
24Glycosaminoglycan degradation_Homo sapiens_hsa005311.40758699
25Prion diseases_Homo sapiens_hsa050201.40021128
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.38144492
27Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.35465923
28Other glycan degradation_Homo sapiens_hsa005111.31802825
29Fat digestion and absorption_Homo sapiens_hsa049751.27927203
30Caffeine metabolism_Homo sapiens_hsa002321.27536467
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.26986904
32Dilated cardiomyopathy_Homo sapiens_hsa054141.25055586
33Propanoate metabolism_Homo sapiens_hsa006401.22238131
34Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.21636322
35Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.15555878
36Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.15007285
37Fatty acid biosynthesis_Homo sapiens_hsa000611.14311572
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.12598877
39Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.12142186
40Small cell lung cancer_Homo sapiens_hsa052221.10059188
41AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.08920305
42Insulin resistance_Homo sapiens_hsa049311.06779066
43Adipocytokine signaling pathway_Homo sapiens_hsa049201.03615153
44Lysine degradation_Homo sapiens_hsa003101.01292110
45Prostate cancer_Homo sapiens_hsa052151.00543280
46ErbB signaling pathway_Homo sapiens_hsa040120.99948207
47Butanoate metabolism_Homo sapiens_hsa006500.99706782
48Central carbon metabolism in cancer_Homo sapiens_hsa052300.96051534
49Acute myeloid leukemia_Homo sapiens_hsa052210.96040548
50Fructose and mannose metabolism_Homo sapiens_hsa000510.96025621
51Pathways in cancer_Homo sapiens_hsa052000.92678316
52Hippo signaling pathway_Homo sapiens_hsa043900.92535665
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.91687332
54Tight junction_Homo sapiens_hsa045300.90331882
55Chronic myeloid leukemia_Homo sapiens_hsa052200.89884978
56Galactose metabolism_Homo sapiens_hsa000520.89721590
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89238587
58Pyruvate metabolism_Homo sapiens_hsa006200.88465154
59Carbon metabolism_Homo sapiens_hsa012000.87212190
60Starch and sucrose metabolism_Homo sapiens_hsa005000.86082639
61Chemical carcinogenesis_Homo sapiens_hsa052040.84728529
62AMPK signaling pathway_Homo sapiens_hsa041520.84714210
63Pentose phosphate pathway_Homo sapiens_hsa000300.83683019
64Glioma_Homo sapiens_hsa052140.83164580
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.80197283
66Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.77251728
67Phenylalanine metabolism_Homo sapiens_hsa003600.75711337
68Insulin signaling pathway_Homo sapiens_hsa049100.75156225
69Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75087627
70MicroRNAs in cancer_Homo sapiens_hsa052060.74456079
71beta-Alanine metabolism_Homo sapiens_hsa004100.73798569
72mTOR signaling pathway_Homo sapiens_hsa041500.73573898
73Glycerolipid metabolism_Homo sapiens_hsa005610.73151080
74Hedgehog signaling pathway_Homo sapiens_hsa043400.72942619
75Basal cell carcinoma_Homo sapiens_hsa052170.72583981
76Biosynthesis of amino acids_Homo sapiens_hsa012300.72490043
77Pentose and glucuronate interconversions_Homo sapiens_hsa000400.71772009
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71625709
79Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71557280
80Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71236622
81Glucagon signaling pathway_Homo sapiens_hsa049220.70176063
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.69937611
83Leukocyte transendothelial migration_Homo sapiens_hsa046700.68735433
84Endometrial cancer_Homo sapiens_hsa052130.68168096
85Choline metabolism in cancer_Homo sapiens_hsa052310.67968348
86Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67098863
87Non-small cell lung cancer_Homo sapiens_hsa052230.66550038
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66210640
89PI3K-Akt signaling pathway_Homo sapiens_hsa041510.65960377
90Selenocompound metabolism_Homo sapiens_hsa004500.65246615
91Gap junction_Homo sapiens_hsa045400.62367547
92TGF-beta signaling pathway_Homo sapiens_hsa043500.61936634
93Estrogen signaling pathway_Homo sapiens_hsa049150.61385455
94N-Glycan biosynthesis_Homo sapiens_hsa005100.61090582
95Endocytosis_Homo sapiens_hsa041440.60387647
96Rap1 signaling pathway_Homo sapiens_hsa040150.60273262
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60061376
98Hepatitis C_Homo sapiens_hsa051600.59208365
99Sphingolipid metabolism_Homo sapiens_hsa006000.58523291
100Wnt signaling pathway_Homo sapiens_hsa043100.57758469
101Melanoma_Homo sapiens_hsa052180.57082975
102Prolactin signaling pathway_Homo sapiens_hsa049170.56946428
103VEGF signaling pathway_Homo sapiens_hsa043700.56830490
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55877470
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55437470
106Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54654126
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.54081690
108Pancreatic cancer_Homo sapiens_hsa052120.53992300
109Peroxisome_Homo sapiens_hsa041460.53057678
110Tyrosine metabolism_Homo sapiens_hsa003500.52510454
111Vibrio cholerae infection_Homo sapiens_hsa051100.52329450
112Platelet activation_Homo sapiens_hsa046110.52036609
113Staphylococcus aureus infection_Homo sapiens_hsa051500.51843623
114Inositol phosphate metabolism_Homo sapiens_hsa005620.51805000
115Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51153441
116Thyroid hormone synthesis_Homo sapiens_hsa049180.50527412
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50194657
118Vascular smooth muscle contraction_Homo sapiens_hsa042700.49965414
119Viral myocarditis_Homo sapiens_hsa054160.48810021
120Renal cell carcinoma_Homo sapiens_hsa052110.48530272
121Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48518380
122Axon guidance_Homo sapiens_hsa043600.48410635
123Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48055251
124ABC transporters_Homo sapiens_hsa020100.47626671
125Vitamin B6 metabolism_Homo sapiens_hsa007500.47594919
126GnRH signaling pathway_Homo sapiens_hsa049120.46935709
127Histidine metabolism_Homo sapiens_hsa003400.46748452
128Melanogenesis_Homo sapiens_hsa049160.46298529
129Toxoplasmosis_Homo sapiens_hsa051450.46192752
130Colorectal cancer_Homo sapiens_hsa052100.46168221
131Type II diabetes mellitus_Homo sapiens_hsa049300.45590512
132HIF-1 signaling pathway_Homo sapiens_hsa040660.44853889
133Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44077634
134Cyanoamino acid metabolism_Homo sapiens_hsa004600.43721578

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