TNPO3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.25577215
2nuclear pore organization (GO:0006999)6.15637556
3DNA unwinding involved in DNA replication (GO:0006268)5.39888903
4protein localization to kinetochore (GO:0034501)5.06211840
5pore complex assembly (GO:0046931)4.77680638
6establishment of integrated proviral latency (GO:0075713)4.54074520
7mitotic nuclear envelope disassembly (GO:0007077)4.48169566
8IMP biosynthetic process (GO:0006188)4.24046598
9protein localization to chromosome, centromeric region (GO:0071459)4.22633302
10membrane disassembly (GO:0030397)4.19827410
11nuclear envelope disassembly (GO:0051081)4.19827410
12mitotic metaphase plate congression (GO:0007080)4.18822793
13regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.14215861
14DNA duplex unwinding (GO:0032508)4.01009418
15DNA geometric change (GO:0032392)3.99162233
16folic acid-containing compound biosynthetic process (GO:0009396)3.94584786
17regulation of spindle organization (GO:0090224)3.91105988
18DNA replication initiation (GO:0006270)3.91069975
19sister chromatid segregation (GO:0000819)3.89583542
20pre-miRNA processing (GO:0031054)3.89270988
21regulation of histone H3-K9 methylation (GO:0051570)3.84311088
22mitotic chromosome condensation (GO:0007076)3.83122631
23mitotic sister chromatid cohesion (GO:0007064)3.81900851
24DNA replication-dependent nucleosome assembly (GO:0006335)3.80547303
25DNA replication-dependent nucleosome organization (GO:0034723)3.80547303
26regulation of helicase activity (GO:0051095)3.79062565
27protein complex localization (GO:0031503)3.72666315
28positive regulation of chromosome segregation (GO:0051984)3.71801631
29metaphase plate congression (GO:0051310)3.71800218
30chromosome condensation (GO:0030261)3.70598792
31nucleobase biosynthetic process (GO:0046112)3.70262510
32mitotic sister chromatid segregation (GO:0000070)3.66418469
33kinetochore organization (GO:0051383)3.65594292
34non-recombinational repair (GO:0000726)3.62378498
35double-strand break repair via nonhomologous end joining (GO:0006303)3.62378498
36regulation of RNA export from nucleus (GO:0046831)3.59383042
37DNA strand elongation involved in DNA replication (GO:0006271)3.57393304
38regulation of posttranscriptional gene silencing (GO:0060147)3.54186260
39regulation of gene silencing by miRNA (GO:0060964)3.54186260
40regulation of gene silencing by RNA (GO:0060966)3.54186260
41chromosome segregation (GO:0007059)3.53166772
42negative regulation of histone methylation (GO:0031061)3.51062888
43establishment of viral latency (GO:0019043)3.48838761
44DNA strand elongation (GO:0022616)3.48816520
45IMP metabolic process (GO:0046040)3.47936211
46protein K6-linked ubiquitination (GO:0085020)3.47582671
47negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.46751051
48negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.46751051
49DNA replication checkpoint (GO:0000076)3.44741940
50DNA ligation (GO:0006266)3.42941377
51regulation of centrosome cycle (GO:0046605)3.41223054
52regulation of mitotic spindle organization (GO:0060236)3.40018755
53COPI coating of Golgi vesicle (GO:0048205)3.38573575
54Golgi transport vesicle coating (GO:0048200)3.38573575
55purine nucleobase biosynthetic process (GO:0009113)3.38252477
56regulation of mitotic sister chromatid separation (GO:0010965)3.38200746
57regulation of mitotic sister chromatid segregation (GO:0033047)3.38200746
58regulation of sister chromatid segregation (GO:0033045)3.38200746
59regulation of sister chromatid cohesion (GO:0007063)3.37055629
60paraxial mesoderm development (GO:0048339)3.35544975
61chromatin remodeling at centromere (GO:0031055)3.32760101
62mitotic spindle assembly checkpoint (GO:0007094)3.32411644
63telomere maintenance via recombination (GO:0000722)3.31975117
64tRNA aminoacylation for protein translation (GO:0006418)3.29229458
65peptidyl-arginine omega-N-methylation (GO:0035247)3.28820456
66positive regulation of mitotic sister chromatid separation (GO:1901970)3.28478815
67positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.28478815
68positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.28478815
69cellular protein complex localization (GO:0034629)3.28044311
70regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.25357037
71DNA packaging (GO:0006323)3.23461552
72regulation of nucleobase-containing compound transport (GO:0032239)3.22363153
73DNA topological change (GO:0006265)3.22216687
74protein localization to chromosome (GO:0034502)3.20896377
75CENP-A containing nucleosome assembly (GO:0034080)3.20762353
76spliceosomal tri-snRNP complex assembly (GO:0000244)3.20639390
77protein-DNA complex disassembly (GO:0032986)3.20617589
78nucleosome disassembly (GO:0006337)3.20617589
79regulation of centriole replication (GO:0046599)3.20131297
80ribosome assembly (GO:0042255)3.19076554
81L-serine metabolic process (GO:0006563)3.18558329
82spindle checkpoint (GO:0031577)3.18342455
83DNA conformation change (GO:0071103)3.18220664
84regulation of translational fidelity (GO:0006450)3.18044429
85intra-S DNA damage checkpoint (GO:0031573)3.18029144
86tRNA aminoacylation (GO:0043039)3.17427211
87amino acid activation (GO:0043038)3.17427211
88regulation of chromosome segregation (GO:0051983)3.17333307
89ATP-dependent chromatin remodeling (GO:0043044)3.16409824
90establishment of chromosome localization (GO:0051303)3.16378117
91nuclear envelope organization (GO:0006998)3.15026728
92protein export from nucleus (GO:0006611)3.14163439
93dosage compensation (GO:0007549)3.13413795
94proline biosynthetic process (GO:0006561)3.13212109
95DNA replication-independent nucleosome organization (GO:0034724)3.12723602
96DNA replication-independent nucleosome assembly (GO:0006336)3.12723602
97regulation of DNA damage checkpoint (GO:2000001)3.12226035
98mitotic recombination (GO:0006312)3.12145337
99regulation of DNA endoreduplication (GO:0032875)3.10609436
100translesion synthesis (GO:0019985)3.06188908
101regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.05137501
102mitotic spindle checkpoint (GO:0071174)3.03808047
103histone H2A monoubiquitination (GO:0035518)3.03677541
104chromatin assembly (GO:0031497)3.03317688
105chromatin assembly or disassembly (GO:0006333)3.01582021
106meiotic chromosome segregation (GO:0045132)3.01397647
107heterochromatin organization (GO:0070828)3.01338354
108mRNA transport (GO:0051028)3.00655105
109negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.99230853
110regulation of centrosome duplication (GO:0010824)2.99225987
111regulation of mitotic metaphase/anaphase transition (GO:0030071)2.98001645
112regulation of telomere maintenance via telomerase (GO:0032210)2.97612071
113kinetochore assembly (GO:0051382)2.96700554
114telomere maintenance via semi-conservative replication (GO:0032201)2.95182994
115histone arginine methylation (GO:0034969)2.93407589
116somatic hypermutation of immunoglobulin genes (GO:0016446)2.92972488
117somatic diversification of immune receptors via somatic mutation (GO:0002566)2.92972488
118spindle assembly checkpoint (GO:0071173)2.92106741
119histone exchange (GO:0043486)2.90607256
120monoubiquitinated protein deubiquitination (GO:0035520)2.89929786
121negative regulation of chromosome segregation (GO:0051985)2.89741929
122regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.88065462
123spindle assembly involved in mitosis (GO:0090307)2.87567805
124formation of translation preinitiation complex (GO:0001731)2.87514142
125attachment of spindle microtubules to kinetochore (GO:0008608)2.86925665
126maturation of SSU-rRNA (GO:0030490)2.86238290
127peptidyl-arginine N-methylation (GO:0035246)2.85062736
128peptidyl-arginine methylation (GO:0018216)2.85062736
129negative regulation of sister chromatid segregation (GO:0033046)2.84925967
130negative regulation of mitotic sister chromatid separation (GO:2000816)2.84925967
131negative regulation of mitotic sister chromatid segregation (GO:0033048)2.84925967

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.58781447
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.56784757
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.78884930
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.38233967
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.29263395
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.28193015
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.03577068
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.88825835
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.76896189
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.60873128
11AR_21909140_ChIP-Seq_LNCAP_Human2.46655893
12* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.39095010
13* E2F1_21310950_ChIP-Seq_MCF-7_Human2.34167507
14* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33098969
15MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.25453225
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.15566214
17TP63_19390658_ChIP-ChIP_HaCaT_Human2.06115167
18* EST1_17652178_ChIP-ChIP_JURKAT_Human2.00139834
19E2F7_22180533_ChIP-Seq_HELA_Human10.9729998
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.98358409
21* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.97686796
22* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96178258
23XRN2_22483619_ChIP-Seq_HELA_Human1.91111600
24* ELK1_19687146_ChIP-ChIP_HELA_Human1.88226007
25* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.87240730
26* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.79551301
27SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.78272142
28KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.74952773
29NANOG_18555785_ChIP-Seq_MESCs_Mouse1.71699804
30CREB1_15753290_ChIP-ChIP_HEK293T_Human1.71287240
31* VDR_23849224_ChIP-Seq_CD4+_Human1.69109016
32* ETS1_20019798_ChIP-Seq_JURKAT_Human1.68604354
33RBPJ_22232070_ChIP-Seq_NCS_Mouse1.64356585
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.62610744
35SOX2_18555785_ChIP-Seq_MESCs_Mouse1.62204886
36HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.58926848
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55805473
38* FOXP3_21729870_ChIP-Seq_TREG_Human1.55524587
39CIITA_25753668_ChIP-Seq_RAJI_Human1.55503833
40PADI4_21655091_ChIP-ChIP_MCF-7_Human1.53377442
41* GABP_17652178_ChIP-ChIP_JURKAT_Human1.52413582
42MYC_22102868_ChIP-Seq_BL_Human1.51706570
43HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.50215745
44MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.49638121
45TTF2_22483619_ChIP-Seq_HELA_Human1.49125685
46POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.43520764
47E2F1_18555785_ChIP-Seq_MESCs_Mouse1.41098164
48DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.40756064
49* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.39694920
50KDM5A_27292631_Chip-Seq_BREAST_Human1.32237245
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.31955826
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.31769836
53KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.29968285
54KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.29968285
55KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.29968285
56POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.29338346
57ESR1_15608294_ChIP-ChIP_MCF-7_Human1.28800307
58* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.27505065
59NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.27504566
60NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.23434752
61SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.23272246
62DCP1A_22483619_ChIP-Seq_HELA_Human1.21912921
63TCF3_18692474_ChIP-Seq_MEFs_Mouse1.21832723
64ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.21589343
65SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.19844934
66E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.19568127
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18292531
68* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17442919
69THAP11_20581084_ChIP-Seq_MESCs_Mouse1.15844960
70NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.12331041
71YY1_21170310_ChIP-Seq_MESCs_Mouse1.10985069
72HOXB4_20404135_ChIP-ChIP_EML_Mouse1.10868977
73BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.10750600
74STAT3_1855785_ChIP-Seq_MESCs_Mouse1.09894836
75KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.08106008
76TCF3_18692474_ChIP-Seq_MESCs_Mouse1.07607528
77POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07001227
78ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.06954441
79TFEB_21752829_ChIP-Seq_HELA_Human1.06343314
80CLOCK_20551151_ChIP-Seq_293T_Human1.03811398
81* GABP_19822575_ChIP-Seq_HepG2_Human1.03625213
82NANOG_16153702_ChIP-ChIP_HESCs_Human1.03593597
83SOX17_20123909_ChIP-Seq_XEN_Mouse1.02888203
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.02868947
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02337881
86TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.01812461
87MYC_18940864_ChIP-ChIP_HL60_Human1.01639854
88WT1_19549856_ChIP-ChIP_CCG9911_Human1.01333384
89SOX2_16153702_ChIP-ChIP_HESCs_Human1.00974377
90SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.99585459
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99577265
92NANOG_21062744_ChIP-ChIP_HESCs_Human0.98989951
93CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97609277
94DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.97406026
95KLF4_18555785_ChIP-Seq_MESCs_Mouse0.97350184
96SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.93711544
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.93696385
98CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93241438
99HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.91986142
100PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.91628276
101* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.90470515
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.90107066
103SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.89413793
104NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.88899566
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88858418
106KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.88490211
107NCOR1_26117541_ChIP-Seq_K562_Human0.87721813
108CHD1_26751641_Chip-Seq_LNCaP_Human0.85895985
109TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.85535229
110* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85505587
111TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.85137842
112* ELF1_17652178_ChIP-ChIP_JURKAT_Human0.84607159
113ERG_20887958_ChIP-Seq_HPC-7_Mouse0.82456068
114NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.80894280
115PKCTHETA_26484144_Chip-Seq_BREAST_Human0.80872105
116* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.79830603
117NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.79205458
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77513972

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.50919940
2MP0008057_abnormal_DNA_replication4.27201145
3MP0003111_abnormal_nucleus_morphology4.00250111
4MP0003077_abnormal_cell_cycle3.47485406
5MP0003693_abnormal_embryo_hatching3.47286761
6MP0004957_abnormal_blastocyst_morpholog3.39017074
7MP0008058_abnormal_DNA_repair3.02540059
8MP0008007_abnormal_cellular_replicative2.76436670
9MP0010307_abnormal_tumor_latency2.71362293
10MP0010352_gastrointestinal_tract_polyps2.70593605
11MP0005076_abnormal_cell_differentiation2.41829827
12MP0003123_paternal_imprinting2.35921520
13MP0000350_abnormal_cell_proliferation2.34638977
14MP0001730_embryonic_growth_arrest2.28015843
15MP0008877_abnormal_DNA_methylation2.24993976
16MP0005451_abnormal_body_composition2.15940775
17MP0003121_genomic_imprinting2.13958033
18MP0003890_abnormal_embryonic-extraembry2.09094927
19MP0003567_abnormal_fetal_cardiomyocyte2.03378044
20MP0008932_abnormal_embryonic_tissue1.96038622
21MP0001672_abnormal_embryogenesis/_devel1.94581913
22MP0005380_embryogenesis_phenotype1.94581913
23MP0004197_abnormal_fetal_growth/weight/1.91747451
24MP0009697_abnormal_copulation1.84085162
25MP0002084_abnormal_developmental_patter1.83950004
26MP0002396_abnormal_hematopoietic_system1.81586005
27MP0001697_abnormal_embryo_size1.76684889
28MP0003984_embryonic_growth_retardation1.75217043
29MP0002085_abnormal_embryonic_tissue1.73476398
30MP0003705_abnormal_hypodermis_morpholog1.72150607
31MP0002088_abnormal_embryonic_growth/wei1.71063990
32MP0000569_abnormal_digit_pigmentation1.64361307
33MP0002086_abnormal_extraembryonic_tissu1.62469220
34MP0002080_prenatal_lethality1.50995548
35MP0000372_irregular_coat_pigmentation1.50533942
36MP0004808_abnormal_hematopoietic_stem1.48967662
37MP0003786_premature_aging1.48006496
38MP0003937_abnormal_limbs/digits/tail_de1.42596623
39MP0001293_anophthalmia1.36410058
40MP0004147_increased_porphyrin_level1.36074413
41MP0000490_abnormal_crypts_of1.34378722
42MP0000537_abnormal_urethra_morphology1.33950140
43MP0010030_abnormal_orbit_morphology1.28663692
44MP0006035_abnormal_mitochondrial_morpho1.28633501
45MP0000428_abnormal_craniofacial_morphol1.24538585
46MP0003787_abnormal_imprinting1.23340039
47MP0002009_preneoplasia1.21672623
48MP0003941_abnormal_skin_development1.18527221
49MP0002697_abnormal_eye_size1.16207013
50MP0003136_yellow_coat_color1.15560760
51MP0000358_abnormal_cell_content/1.14916675
52MP0009703_decreased_birth_body1.14185121
53MP0000313_abnormal_cell_death1.13902865
54MP0008260_abnormal_autophagy1.12647723
55MP0009053_abnormal_anal_canal1.09437013
56MP0009672_abnormal_birth_weight1.08227084
57MP0010234_abnormal_vibrissa_follicle1.08197030
58MP0002019_abnormal_tumor_incidence1.06341581
59MP0003566_abnormal_cell_adhesion1.04308202
60MP0001286_abnormal_eye_development1.02287815
61MP0001915_intracranial_hemorrhage1.02093979
62MP0004133_heterotaxia1.00269707
63MP0003119_abnormal_digestive_system1.00065474
64MP0002092_abnormal_eye_morphology0.99842346
65MP0002111_abnormal_tail_morphology0.99651904
66MP0001849_ear_inflammation0.99465863
67MP0004264_abnormal_extraembryonic_tissu0.99360317
68MP0003656_abnormal_erythrocyte_physiolo0.98204570
69MP0004185_abnormal_adipocyte_glucose0.97664064
70MP0005394_taste/olfaction_phenotype0.96499471
71MP0005499_abnormal_olfactory_system0.96499471
72MP0002877_abnormal_melanocyte_morpholog0.95886045
73MP0000432_abnormal_head_morphology0.95789412
74MP0000703_abnormal_thymus_morphology0.95084248
75MP0000371_diluted_coat_color0.93312360
76MP0003935_abnormal_craniofacial_develop0.92843672
77MP0003861_abnormal_nervous_system0.91186785
78MP0003115_abnormal_respiratory_system0.90492579
79MP0002210_abnormal_sex_determination0.88962588
80MP0003755_abnormal_palate_morphology0.88608615
81MP0003718_maternal_effect0.87152569
82MP0005171_absent_coat_pigmentation0.83957479
83MP0004233_abnormal_muscle_weight0.83825726
84MP0005367_renal/urinary_system_phenotyp0.83573898
85MP0000516_abnormal_urinary_system0.83573898
86MP0000383_abnormal_hair_follicle0.80285475
87MP0003221_abnormal_cardiomyocyte_apopto0.80242634
88MP0001929_abnormal_gametogenesis0.78926057
89MP0002075_abnormal_coat/hair_pigmentati0.77929953
90MP0000733_abnormal_muscle_development0.77453246
91MP0010678_abnormal_skin_adnexa0.77393517
92MP0005384_cellular_phenotype0.75974502
93MP0003950_abnormal_plasma_membrane0.75802608
94MP0001727_abnormal_embryo_implantation0.74928084
95MP0001145_abnormal_male_reproductive0.74892326
96MP0002925_abnormal_cardiovascular_devel0.74199736
97MP0002254_reproductive_system_inflammat0.74089938
98MP0005501_abnormal_skin_physiology0.74008319
99MP0005397_hematopoietic_system_phenotyp0.73847463
100MP0001545_abnormal_hematopoietic_system0.73847463
101MP0002160_abnormal_reproductive_system0.73801134
102MP0005621_abnormal_cell_physiology0.73393812
103MP0000627_abnormal_mammary_gland0.72108272
104MP0002269_muscular_atrophy0.72045044
105MP0002938_white_spotting0.71606980
106MP0003699_abnormal_female_reproductive0.70689410
107MP0001299_abnormal_eye_distance/0.70508668
108MP0005623_abnormal_meninges_morphology0.70474740
109MP0008770_decreased_survivor_rate0.69294541
110MP0000647_abnormal_sebaceous_gland0.68478742
111MP0001529_abnormal_vocalization0.68175234
112MP0001348_abnormal_lacrimal_gland0.67338053
113MP0002090_abnormal_vision0.67196497
114MP0005257_abnormal_intraocular_pressure0.66476439
115MP0002081_perinatal_lethality0.65032972
116MP0003938_abnormal_ear_development0.64153272
117MP0003385_abnormal_body_wall0.64123688
118MP0009278_abnormal_bone_marrow0.63845543
119MP0001186_pigmentation_phenotype0.63834202
120MP0005389_reproductive_system_phenotype0.63005049
121MP0002163_abnormal_gland_morphology0.62649594
122MP0002722_abnormal_immune_system0.62584888
123MP0006292_abnormal_olfactory_placode0.61694983
124MP0002398_abnormal_bone_marrow0.61672610
125MP0008789_abnormal_olfactory_epithelium0.61458628
126MP0003315_abnormal_perineum_morphology0.61394730
127MP0002233_abnormal_nose_morphology0.61238614

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.12640682
2Cortical dysplasia (HP:0002539)5.06069833
3Chromosomal breakage induced by crosslinking agents (HP:0003221)5.05122812
4Cholecystitis (HP:0001082)3.86928119
5Abnormal gallbladder physiology (HP:0012438)3.86928119
6Ependymoma (HP:0002888)3.86003191
7Spastic diplegia (HP:0001264)3.56484225
8Selective tooth agenesis (HP:0001592)3.31038713
9Volvulus (HP:0002580)3.28955658
10Astrocytoma (HP:0009592)3.15212382
11Abnormality of the astrocytes (HP:0100707)3.15212382
12Colon cancer (HP:0003003)3.13548067
13Medulloblastoma (HP:0002885)3.10004312
14Termporal pattern (HP:0011008)3.07492067
15Insidious onset (HP:0003587)3.07492067
16Abnormality of chromosome stability (HP:0003220)3.06872401
17Abnormality of the labia minora (HP:0012880)2.97340146
18Multiple enchondromatosis (HP:0005701)2.94188845
19Meckel diverticulum (HP:0002245)2.77800802
20Ectopic kidney (HP:0000086)2.74677349
21Cutaneous melanoma (HP:0012056)2.74626943
22Microvesicular hepatic steatosis (HP:0001414)2.73975876
23Birth length less than 3rd percentile (HP:0003561)2.68608684
24Abnormality of the preputium (HP:0100587)2.67135753
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.64972062
26Abnormality of the ileum (HP:0001549)2.64416983
27Glioma (HP:0009733)2.63895255
28Progressive external ophthalmoplegia (HP:0000590)2.62682649
29Reticulocytopenia (HP:0001896)2.62221504
30Impulsivity (HP:0100710)2.60076225
31Breast hypoplasia (HP:0003187)2.53416088
32Abdominal situs inversus (HP:0003363)2.50887526
33Abnormality of abdominal situs (HP:0011620)2.50887526
34Insomnia (HP:0100785)2.49873701
35Patellar aplasia (HP:0006443)2.48934301
36Duplicated collecting system (HP:0000081)2.48009184
37Proximal placement of thumb (HP:0009623)2.47358852
38Increased nuchal translucency (HP:0010880)2.46436861
39Hyperacusis (HP:0010780)2.44925363
40Abnormal number of incisors (HP:0011064)2.43903069
41Ankyloglossia (HP:0010296)2.41817551
42Deviation of the thumb (HP:0009603)2.40149417
43Absent radius (HP:0003974)2.39731614
44Agnosia (HP:0010524)2.38430880
45Rhabdomyosarcoma (HP:0002859)2.38141863
46Malignant gastrointestinal tract tumors (HP:0006749)2.37326651
47Gastrointestinal carcinoma (HP:0002672)2.37326651
48Prominent nose (HP:0000448)2.31124506
49Aplasia/Hypoplasia of the patella (HP:0006498)2.30228738
50Myelodysplasia (HP:0002863)2.28292576
51Aplasia involving forearm bones (HP:0009822)2.25561302
52Absent forearm bone (HP:0003953)2.25561302
53Abnormality of the carotid arteries (HP:0005344)2.24376853
54Overriding aorta (HP:0002623)2.24357490
55Missing ribs (HP:0000921)2.23403229
56Small intestinal stenosis (HP:0012848)2.23307405
57Duodenal stenosis (HP:0100867)2.23307405
58Neoplasm of the pancreas (HP:0002894)2.20802025
59Short 4th metacarpal (HP:0010044)2.19811007
60Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.19811007
61Sloping forehead (HP:0000340)2.18004398
62Abnormality of the renal collecting system (HP:0004742)2.16225040
63Neoplasm of the oral cavity (HP:0100649)2.15850303
64Upper limb muscle weakness (HP:0003484)2.15478021
65Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.11447895
66Dysmetric saccades (HP:0000641)2.11046220
67Abnormality of glycolysis (HP:0004366)2.10363540
68Biliary tract neoplasm (HP:0100574)2.09065643
69Abnormality of reticulocytes (HP:0004312)2.07770712
70Reticulocytosis (HP:0001923)2.07758109
71Abnormal lung lobation (HP:0002101)2.07218165
72Facial hemangioma (HP:0000329)2.06785165
73Cafe-au-lait spot (HP:0000957)2.06666407
74Progressive muscle weakness (HP:0003323)2.03794881
75Papillary thyroid carcinoma (HP:0002895)2.03624333
76Long eyelashes (HP:0000527)2.03252269
77Amaurosis fugax (HP:0100576)2.02999124
78Abnormality of oral frenula (HP:0000190)2.02786509
79Absent thumb (HP:0009777)2.02395124
80Sparse lateral eyebrow (HP:0005338)2.01572831
81Supernumerary spleens (HP:0009799)2.01117884
82Abnormality of DNA repair (HP:0003254)2.00372346
83Abnormality of the duodenum (HP:0002246)1.99278759
84Premature ovarian failure (HP:0008209)1.98122876
85High anterior hairline (HP:0009890)1.97619414
86Nephroblastoma (Wilms tumor) (HP:0002667)1.96819186
8711 pairs of ribs (HP:0000878)1.94179273
88Blepharitis (HP:0000498)1.94121977
89Long palpebral fissure (HP:0000637)1.93185182
90Tracheoesophageal fistula (HP:0002575)1.92710044
91Aplasia/Hypoplasia of the sternum (HP:0006714)1.92538970
92Supernumerary ribs (HP:0005815)1.92061481
93Abnormality of the peritoneum (HP:0002585)1.90190773
94Skull defect (HP:0001362)1.88866526
95Syringomyelia (HP:0003396)1.87759280
96Spinal cord lesions (HP:0100561)1.87759280
97Urethral obstruction (HP:0000796)1.87738119
98Embryonal renal neoplasm (HP:0011794)1.87273084
99Supernumerary bones of the axial skeleton (HP:0009144)1.86712577
100Choanal atresia (HP:0000453)1.86684353
101Horseshoe kidney (HP:0000085)1.86417675
102Cholelithiasis (HP:0001081)1.85984515
103Low anterior hairline (HP:0000294)1.85668402
104Glossoptosis (HP:0000162)1.84164099
105Overlapping toe (HP:0001845)1.83809308
106Basal cell carcinoma (HP:0002671)1.83683678
107Abnormality of the calcaneus (HP:0008364)1.82854683
108Esophageal atresia (HP:0002032)1.82198847
109Neoplasm of striated muscle (HP:0009728)1.80685244
110Homocystinuria (HP:0002156)1.80402320
111Abnormality of homocysteine metabolism (HP:0010919)1.80402320
112Relative macrocephaly (HP:0004482)1.80246834
113Aplasia/hypoplasia of the humerus (HP:0006507)1.80033044
114Elfin facies (HP:0004428)1.79439491
115Neoplasm of the colon (HP:0100273)1.78045496
116Orthostatic hypotension (HP:0001278)1.77441271
117Bone marrow hypocellularity (HP:0005528)1.75985313
118Secondary amenorrhea (HP:0000869)1.74832569
119Abnormality of chromosome segregation (HP:0002916)1.74529101
120Aplasia/Hypoplasia of the earlobes (HP:0009906)1.74451970
121Sandal gap (HP:0001852)1.73977233
122Short thumb (HP:0009778)1.73899422
123Neoplasm of the respiratory system (HP:0100606)1.73309342
124Cutis marmorata (HP:0000965)1.72966526
125Embryonal neoplasm (HP:0002898)1.72872311
126Leiomyosarcoma (HP:0100243)1.71485768
127Uterine leiomyosarcoma (HP:0002891)1.71485768
128Abnormality of cochlea (HP:0000375)1.71172390
129Deep philtrum (HP:0002002)1.70942822
130Freckling (HP:0001480)1.70733773
131Abnormality of the antihelix (HP:0009738)1.69665881
132Short humerus (HP:0005792)1.69423496
133Increased serum pyruvate (HP:0003542)1.69414846
134Asymmetry of the thorax (HP:0001555)1.69091158
135Transitional cell carcinoma of the bladder (HP:0006740)1.69054062
136Squamous cell carcinoma (HP:0002860)1.68847727
137Hammertoe (HP:0001765)1.68021247
138Uterine neoplasm (HP:0010784)1.66633164
139Degeneration of anterior horn cells (HP:0002398)1.66500982
140Abnormality of the anterior horn cell (HP:0006802)1.66500982
141Benign neoplasm of the central nervous system (HP:0100835)1.66201780
142Heterotopia (HP:0002282)1.65980736
143Neuroblastoma (HP:0003006)1.64579134
144Primitive neuroectodermal tumor (HP:0030065)1.64579134
145Neuroblastic tumors (HP:0004376)1.64579134
146Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.64579134
147Pointed chin (HP:0000307)1.63441142
148Premature skin wrinkling (HP:0100678)1.62765264
149Flat cornea (HP:0007720)1.62629405
150Breech presentation (HP:0001623)1.61742233
151Obsessive-compulsive behavior (HP:0000722)1.61359711
152Renal duplication (HP:0000075)1.58995675
153Bowel incontinence (HP:0002607)1.58982064
154Trismus (HP:0000211)1.56628033
155Facial cleft (HP:0002006)1.56431645
156Abnormal large intestine physiology (HP:0012700)1.54757389
157Generalized hypotonia (HP:0001290)1.54751821
158Deep palmar crease (HP:0006191)1.54449721
159Abnormal gallbladder morphology (HP:0012437)1.54442695
160Postnatal microcephaly (HP:0005484)1.54354682

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.13147988
2MKNK13.32741141
3MKNK23.31366030
4WEE13.30709186
5SRPK13.00425252
6CDK122.91562898
7BUB12.70737875
8PBK2.69637586
9NEK22.60308351
10PLK32.31602495
11TSSK62.29378833
12BRSK22.24821477
13TTK2.24755659
14EEF2K2.23694526
15RPS6KB22.12820299
16EPHA21.99098762
17ATR1.94873403
18LATS11.86486294
19PLK11.80966173
20BRD41.80706966
21SMG11.70331474
22NEK11.68030177
23PASK1.65426100
24SCYL21.63524798
25PNCK1.60056028
26CHEK11.57394703
27CDK41.56420077
28AURKB1.54764929
29ICK1.51119964
30TLK11.49430376
31STK31.49020288
32CHEK21.48688358
33CLK11.46900310
34ZAK1.46488291
35CDK71.45334358
36KSR21.43268660
37ATM1.36589043
38CDK61.32627105
39VRK11.30623105
40STK101.30414569
41BRAF1.27449275
42STK41.27392139
43PLK41.27204402
44ACVR1B1.26057126
45MAP3K81.21137138
46TRIB31.18651248
47DYRK31.12770829
48BRSK11.11135215
49PIM11.10341699
50CDK21.08065869
51RAF11.02930905
52LATS21.02388061
53EIF2AK11.00432610
54TRIM281.00241513
55STK38L0.99681140
56IRAK30.99437160
57ALK0.99183859
58BCR0.97049410
59TTN0.96664079
60MAP3K100.95609867
61MTOR0.95523139
62MARK30.94108503
63FLT30.93453619
64AURKA0.92622640
65RPS6KA40.92349324
66CDK10.89406604
67PRPF4B0.88558836
68PLK20.87673764
69PAK40.86761397
70NME20.85177854
71PKN20.82936455
72CDK80.81850087
73TGFBR10.80989555
74MELK0.76737389
75FGFR10.75434281
76EIF2AK20.74081891
77CSNK1D0.73991056
78VRK20.72885350
79NUAK10.70256781
80CSNK2A20.69228107
81MAP3K40.68468492
82CSNK1E0.67206749
83FGFR40.67041918
84AKT20.65759516
85PRKDC0.65754312
86MAP3K90.63908262
87TESK20.63713988
88YES10.63230845
89STK160.62460060
90NEK90.62448205
91ERBB30.60938257
92CDK11A0.60368059
93PAK20.60196406
94CDK150.60073636
95CDK180.59934142
96MET0.59375223
97MAPK140.58126213
98EIF2AK30.57681019
99CDK140.55761571
100CHUK0.53462633
101TAF10.52691464
102AKT30.51250441
103RPS6KA50.48461022
104RPS6KB10.48358072
105MST1R0.46778731
106PRKCI0.46744101
107JAK30.46693166
108CDK90.46475673
109AKT10.45694321
110CSNK2A10.43695151
111GSK3B0.42791799
112RIPK10.42014818
113PDGFRA0.40644084
114PTK60.40276925
115NME10.39493131
116EPHA30.39235566
117STK240.35526685
118MAPK10.32928743
119CCNB10.32909583
120CAMK1D0.32463742
121KSR10.31712422
122MAP3K50.31675962
123PDK20.31253888
124MAPK100.31219686
125PAK10.30506528
126MAPK80.28481567
127PDGFRB0.26745137
128BMX0.22746839
129MAPK90.22342617
130ERBB40.20783308

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.83648557
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.73333731
3Mismatch repair_Homo sapiens_hsa034303.68960536
4RNA transport_Homo sapiens_hsa030133.46721001
5Spliceosome_Homo sapiens_hsa030403.18286146
6One carbon pool by folate_Homo sapiens_hsa006703.15177833
7Cell cycle_Homo sapiens_hsa041102.92625254
8Homologous recombination_Homo sapiens_hsa034402.82797043
9Non-homologous end-joining_Homo sapiens_hsa034502.72597172
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.66479482
11Fanconi anemia pathway_Homo sapiens_hsa034602.46822449
12Nucleotide excision repair_Homo sapiens_hsa034202.44478405
13Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.38414523
14RNA polymerase_Homo sapiens_hsa030202.33768523
15mRNA surveillance pathway_Homo sapiens_hsa030152.21359698
16Base excision repair_Homo sapiens_hsa034102.18644441
17Systemic lupus erythematosus_Homo sapiens_hsa053222.09404388
18p53 signaling pathway_Homo sapiens_hsa041152.07570996
19RNA degradation_Homo sapiens_hsa030181.91593685
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.72325059
21Carbon metabolism_Homo sapiens_hsa012001.66881395
22Viral carcinogenesis_Homo sapiens_hsa052031.65603815
23Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.64082761
24Basal transcription factors_Homo sapiens_hsa030221.62240157
25MicroRNAs in cancer_Homo sapiens_hsa052061.48520223
26Pyrimidine metabolism_Homo sapiens_hsa002401.44189368
27Epstein-Barr virus infection_Homo sapiens_hsa051691.38321956
28Steroid biosynthesis_Homo sapiens_hsa001001.33034841
29Ribosome_Homo sapiens_hsa030101.26254273
30Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.25826136
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.24038433
32Proteasome_Homo sapiens_hsa030501.21940822
33Small cell lung cancer_Homo sapiens_hsa052221.15806453
34Oocyte meiosis_Homo sapiens_hsa041141.14537864
35Herpes simplex infection_Homo sapiens_hsa051681.12717268
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.11773104
37Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.09742540
38Pyruvate metabolism_Homo sapiens_hsa006201.09717628
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.08122704
40HTLV-I infection_Homo sapiens_hsa051661.07137059
41Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05399476
42Alcoholism_Homo sapiens_hsa050341.01126086
43Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.97970420
44Hippo signaling pathway_Homo sapiens_hsa043900.96136974
45Antigen processing and presentation_Homo sapiens_hsa046120.92356322
46Viral myocarditis_Homo sapiens_hsa054160.92339363
47Adherens junction_Homo sapiens_hsa045200.89403673
48Lysine degradation_Homo sapiens_hsa003100.86969989
49Basal cell carcinoma_Homo sapiens_hsa052170.84977835
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.84918534
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84698880
52Chronic myeloid leukemia_Homo sapiens_hsa052200.84117457
53Colorectal cancer_Homo sapiens_hsa052100.83368238
54mTOR signaling pathway_Homo sapiens_hsa041500.80971457
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.78698558
56TGF-beta signaling pathway_Homo sapiens_hsa043500.77062901
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73252111
58Thyroid cancer_Homo sapiens_hsa052160.73102469
59Prostate cancer_Homo sapiens_hsa052150.72598923
60Vitamin B6 metabolism_Homo sapiens_hsa007500.70480570
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70393809
62Purine metabolism_Homo sapiens_hsa002300.70231584
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.68163683
64Fructose and mannose metabolism_Homo sapiens_hsa000510.67194560
65Apoptosis_Homo sapiens_hsa042100.67105084
66NF-kappa B signaling pathway_Homo sapiens_hsa040640.66651279
67Central carbon metabolism in cancer_Homo sapiens_hsa052300.66590353
68Hepatitis B_Homo sapiens_hsa051610.65208889
69Cyanoamino acid metabolism_Homo sapiens_hsa004600.64288309
70Selenocompound metabolism_Homo sapiens_hsa004500.62908734
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.61523324
72Primary immunodeficiency_Homo sapiens_hsa053400.60497716
73Legionellosis_Homo sapiens_hsa051340.60313023
74Notch signaling pathway_Homo sapiens_hsa043300.59683831
75Melanoma_Homo sapiens_hsa052180.56406870
76Insulin signaling pathway_Homo sapiens_hsa049100.55820013
77FoxO signaling pathway_Homo sapiens_hsa040680.55688435
78Biosynthesis of amino acids_Homo sapiens_hsa012300.55606543
79Pathways in cancer_Homo sapiens_hsa052000.55060895
80ErbB signaling pathway_Homo sapiens_hsa040120.54411971
81Hedgehog signaling pathway_Homo sapiens_hsa043400.54279214
82HIF-1 signaling pathway_Homo sapiens_hsa040660.54246160
83Proteoglycans in cancer_Homo sapiens_hsa052050.53242204
84Galactose metabolism_Homo sapiens_hsa000520.52046568
85N-Glycan biosynthesis_Homo sapiens_hsa005100.51344698
86Endometrial cancer_Homo sapiens_hsa052130.49805021
87Fatty acid elongation_Homo sapiens_hsa000620.49750454
88Measles_Homo sapiens_hsa051620.49257124
89Wnt signaling pathway_Homo sapiens_hsa043100.48365517
90Non-small cell lung cancer_Homo sapiens_hsa052230.47209431
91Bladder cancer_Homo sapiens_hsa052190.47010096
92Acute myeloid leukemia_Homo sapiens_hsa052210.45784130
93Fatty acid metabolism_Homo sapiens_hsa012120.45207683
94Tight junction_Homo sapiens_hsa045300.45114973
95Pancreatic cancer_Homo sapiens_hsa052120.41554552
96Influenza A_Homo sapiens_hsa051640.41092716
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.40203520
98T cell receptor signaling pathway_Homo sapiens_hsa046600.39524689
99Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38105432
100PI3K-Akt signaling pathway_Homo sapiens_hsa041510.37137258
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36860138
102Arginine biosynthesis_Homo sapiens_hsa002200.36750121
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34512064
104Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33104410
105Renal cell carcinoma_Homo sapiens_hsa052110.33067871
106Pentose phosphate pathway_Homo sapiens_hsa000300.32379349
107Arginine and proline metabolism_Homo sapiens_hsa003300.32349593
108Gap junction_Homo sapiens_hsa045400.30694711
109Propanoate metabolism_Homo sapiens_hsa006400.30615328
110Vibrio cholerae infection_Homo sapiens_hsa051100.29958997
111Autoimmune thyroid disease_Homo sapiens_hsa053200.29229040
112Leukocyte transendothelial migration_Homo sapiens_hsa046700.28849132
113Shigellosis_Homo sapiens_hsa051310.28680021
114Cysteine and methionine metabolism_Homo sapiens_hsa002700.28023742
115AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.27882178
116Focal adhesion_Homo sapiens_hsa045100.27216258
117TNF signaling pathway_Homo sapiens_hsa046680.27026433
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26548656
119Type I diabetes mellitus_Homo sapiens_hsa049400.26080691
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.24753140
121Neurotrophin signaling pathway_Homo sapiens_hsa047220.24742924
122Glioma_Homo sapiens_hsa052140.24630451
123Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.24194029
124AMPK signaling pathway_Homo sapiens_hsa041520.23095953
125Inositol phosphate metabolism_Homo sapiens_hsa005620.22006015
126Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.21656561
127Allograft rejection_Homo sapiens_hsa053300.21318491
128ECM-receptor interaction_Homo sapiens_hsa045120.20642382
129B cell receptor signaling pathway_Homo sapiens_hsa046620.19307844
130RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.17673828

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