TNRC6B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)4.92731294
2histone H3-K4 trimethylation (GO:0080182)4.46158466
3cytoplasmic mRNA processing body assembly (GO:0033962)4.11421417
4retinal cone cell development (GO:0046549)3.57910451
5presynaptic membrane assembly (GO:0097105)3.55744769
6pyrimidine nucleobase catabolic process (GO:0006208)3.54246143
7retrograde transport, vesicle recycling within Golgi (GO:0000301)3.44363961
8histone H3-K4 methylation (GO:0051568)3.44067352
9mitotic sister chromatid cohesion (GO:0007064)3.42834423
10embryonic retina morphogenesis in camera-type eye (GO:0060059)3.35398125
11neural tube formation (GO:0001841)3.32746192
12negative regulation of translation, ncRNA-mediated (GO:0040033)3.27791655
13regulation of translation, ncRNA-mediated (GO:0045974)3.27791655
14negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.27791655
15protein targeting to Golgi (GO:0000042)3.27272742
16gamma-aminobutyric acid transport (GO:0015812)3.23053833
17presynaptic membrane organization (GO:0097090)3.19973233
18L-fucose catabolic process (GO:0042355)3.17150654
19fucose catabolic process (GO:0019317)3.17150654
20L-fucose metabolic process (GO:0042354)3.17150654
21startle response (GO:0001964)3.13390567
22cerebellar Purkinje cell differentiation (GO:0021702)3.12251447
23regulation of rhodopsin mediated signaling pathway (GO:0022400)3.12050174
24establishment of protein localization to Golgi (GO:0072600)3.11358138
25DNA deamination (GO:0045006)3.08792590
26rhodopsin mediated signaling pathway (GO:0016056)3.08436049
27kidney morphogenesis (GO:0060993)3.08262641
28peptidyl-lysine trimethylation (GO:0018023)3.08245076
29neuronal action potential (GO:0019228)3.07469530
30epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.06117096
31nucleobase catabolic process (GO:0046113)3.03016257
32insulin-like growth factor receptor signaling pathway (GO:0048009)2.98610937
33heart field specification (GO:0003128)2.98205188
34secondary heart field specification (GO:0003139)2.98205188
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.93440324
36histone H3-K9 demethylation (GO:0033169)2.91991413
37serotonin metabolic process (GO:0042428)2.91897120
38response to pheromone (GO:0019236)2.91766623
39regulation of telomere maintenance (GO:0032204)2.88583004
40regulation of ARF protein signal transduction (GO:0032012)2.86838521
41dopamine biosynthetic process (GO:0042416)2.83695178
42spinal cord motor neuron differentiation (GO:0021522)2.82565692
43alkaloid metabolic process (GO:0009820)2.82019063
44glutamate receptor signaling pathway (GO:0007215)2.79515074
45stress granule assembly (GO:0034063)2.78987377
46detection of light stimulus involved in visual perception (GO:0050908)2.78920997
47detection of light stimulus involved in sensory perception (GO:0050962)2.78920997
48histone lysine methylation (GO:0034968)2.78218511
49locomotory exploration behavior (GO:0035641)2.78105675
50protein polyglutamylation (GO:0018095)2.75876810
51protein K11-linked deubiquitination (GO:0035871)2.75792962
52positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.74940030
53positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.74477420
54neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.72407259
55histone H3-K36 demethylation (GO:0070544)2.71415678
56positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.69656476
57neuron cell-cell adhesion (GO:0007158)2.68837443
58regulation of short-term neuronal synaptic plasticity (GO:0048172)2.68771398
59negative regulation of cell killing (GO:0031342)2.67537298
60negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.67537298
61establishment of nucleus localization (GO:0040023)2.67264648
62synapse assembly (GO:0007416)2.66923871
63nucleus localization (GO:0051647)2.66092289
64negative regulation of systemic arterial blood pressure (GO:0003085)2.65251887
65otic vesicle formation (GO:0030916)2.64109082
66primary amino compound metabolic process (GO:1901160)2.63240978
67photoreceptor cell development (GO:0042461)2.62097529
68indolalkylamine metabolic process (GO:0006586)2.60726099
69eye photoreceptor cell development (GO:0042462)2.60311637
70reflex (GO:0060004)2.59701949
71photoreceptor cell maintenance (GO:0045494)2.58512965
72hindbrain development (GO:0030902)2.58472568
73cell proliferation in forebrain (GO:0021846)2.58273111
74regulation of mesoderm development (GO:2000380)2.57041127
75synaptic transmission, cholinergic (GO:0007271)2.56958196
76positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.56586705
77regulation of action potential (GO:0098900)2.56535136
78peptidyl-threonine phosphorylation (GO:0018107)2.55689314
79adaptation of signaling pathway (GO:0023058)2.55571445
80epithelial cilium movement (GO:0003351)2.55094282
81regulation of calcium ion-dependent exocytosis (GO:0017158)2.54123741
82histone lysine demethylation (GO:0070076)2.53406563
83positive regulation of histone deacetylation (GO:0031065)2.53230346
84sulfation (GO:0051923)2.53157918
85sodium ion export (GO:0071436)2.53012638
86cardiac ventricle formation (GO:0003211)2.51697329
87limb bud formation (GO:0060174)2.51527090
88action potential (GO:0001508)2.49746757
89neuron-neuron synaptic transmission (GO:0007270)2.49652666
90pre-miRNA processing (GO:0031054)2.48477502
91heart morphogenesis (GO:0003007)2.48289783
92somite rostral/caudal axis specification (GO:0032525)2.48238349
93cellular anion homeostasis (GO:0030002)2.48075599
94water-soluble vitamin biosynthetic process (GO:0042364)2.47950787
95inositol phosphate catabolic process (GO:0071545)2.47458133
96transmission of nerve impulse (GO:0019226)2.46986939
97synaptic transmission, glutamatergic (GO:0035249)2.46742539
98G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.46675752
99regulation of clathrin-mediated endocytosis (GO:2000369)2.46664941
100dendrite morphogenesis (GO:0048813)2.46209309
101dentate gyrus development (GO:0021542)2.45867218
102regulation of collateral sprouting (GO:0048670)2.44989138
103cAMP catabolic process (GO:0006198)2.44354881
104protein localization to Golgi apparatus (GO:0034067)2.42859733
105somite development (GO:0061053)2.41967404
106regulation of acrosome reaction (GO:0060046)2.41906912
107phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.41339372
108cellular potassium ion homeostasis (GO:0030007)2.41202844
109peptidyl-threonine modification (GO:0018210)2.39350387
110specification of organ identity (GO:0010092)2.38007832
111cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.37882728
112retinal ganglion cell axon guidance (GO:0031290)2.37869904
113interkinetic nuclear migration (GO:0022027)2.37306924
114auditory behavior (GO:0031223)2.37055819
115regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.37000385
116cardiac chamber formation (GO:0003207)2.36962713
117photoreceptor cell differentiation (GO:0046530)2.36782027
118eye photoreceptor cell differentiation (GO:0001754)2.36782027
119negative regulation of transcription regulatory region DNA binding (GO:2000678)2.36387066
120positive regulation of cardiac muscle cell differentiation (GO:2000727)2.36058830
121prostate gland growth (GO:0060736)2.33132590
122peptidyl-lysine methylation (GO:0018022)2.33033518
123regulation of neurotransmitter uptake (GO:0051580)2.32779242
124postsynaptic membrane organization (GO:0001941)2.31755480
125retinal rod cell development (GO:0046548)2.31729637
126growth hormone receptor signaling pathway (GO:0060396)2.31323193
127platelet dense granule organization (GO:0060155)2.31140515
128histone demethylation (GO:0016577)2.30161628
129cyclic nucleotide catabolic process (GO:0009214)2.30056146
130behavioral response to ethanol (GO:0048149)2.29566242
131axoneme assembly (GO:0035082)2.29145902
132proline transport (GO:0015824)2.26694347
133indole-containing compound metabolic process (GO:0042430)2.26649297
134limb development (GO:0060173)2.26497277
135regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.24988141
136* positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.24792341
137* regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.24792341
138nerve growth factor signaling pathway (GO:0038180)2.23905289
139potassium ion import (GO:0010107)2.21317713
140synaptic vesicle maturation (GO:0016188)2.20553526
141Golgi to endosome transport (GO:0006895)2.19406250
142regulation of RNA export from nucleus (GO:0046831)2.18035042
143positive T cell selection (GO:0043368)2.17121584
144dendritic spine morphogenesis (GO:0060997)2.17056001
145membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.16179729
146cardiac myofibril assembly (GO:0055003)2.15042040
147positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.14944742
148activated T cell proliferation (GO:0050798)2.14430896
149innervation (GO:0060384)2.13831223
150cytoskeletal anchoring at plasma membrane (GO:0007016)2.13248649
151vocalization behavior (GO:0071625)2.13087704
152phospholipid translocation (GO:0045332)2.12641153
153lipid translocation (GO:0034204)2.12641153
154* positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.11125097
155* regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.11125097
156regulation of nucleobase-containing compound transport (GO:0032239)2.10492676
157retina layer formation (GO:0010842)2.09805370
158membrane depolarization during action potential (GO:0086010)2.08816366
159negative regulation of cytosolic calcium ion concentration (GO:0051481)2.08633204
160positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.07526082
161asymmetric protein localization (GO:0008105)2.07458031
162regulation of histone deacetylation (GO:0031063)2.07336099
163histone methylation (GO:0016571)2.06662150
164glucocorticoid receptor signaling pathway (GO:0042921)2.06276413
165histone H3-K9 modification (GO:0061647)2.06123318
166protein localization to synapse (GO:0035418)2.05830316
167chemosensory behavior (GO:0007635)2.04979736
168NLS-bearing protein import into nucleus (GO:0006607)2.04228543
169positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.03796815
170protein dealkylation (GO:0008214)2.01524945
171protein demethylation (GO:0006482)2.01524945
172ionotropic glutamate receptor signaling pathway (GO:0035235)2.01207293
173regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.01016767
174cell communication by electrical coupling (GO:0010644)2.00667117
175layer formation in cerebral cortex (GO:0021819)2.00106725
176adult heart development (GO:0007512)2.00036469
177histone H3-K9 methylation (GO:0051567)1.99929522
178protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)1.97896469
179regulation of Rap GTPase activity (GO:0032317)1.96245821

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.14668766
2GBX2_23144817_ChIP-Seq_PC3_Human2.61017629
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.43614059
4VDR_22108803_ChIP-Seq_LS180_Human2.39197611
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.37333821
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.35158771
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.23334324
8CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.20627873
9IGF1R_20145208_ChIP-Seq_DFB_Human2.13424061
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.12077490
11DROSHA_22980978_ChIP-Seq_HELA_Human2.08233880
12SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.03789528
13SMAD_19615063_ChIP-ChIP_OVARY_Human2.02370631
14FLI1_27457419_Chip-Seq_LIVER_Mouse1.93655196
15VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.90429108
16AR_21572438_ChIP-Seq_LNCaP_Human1.85689184
17EWS_26573619_Chip-Seq_HEK293_Human1.84186644
18* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.81788282
19ZNF217_24962896_ChIP-Seq_MCF-7_Human1.73395532
20PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70862960
21TP53_16413492_ChIP-PET_HCT116_Human1.67922088
22ER_23166858_ChIP-Seq_MCF-7_Human1.65854276
23SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.63331628
24SMAD4_21799915_ChIP-Seq_A2780_Human1.60817433
25JARID2_20064375_ChIP-Seq_MESCs_Mouse1.58721100
26UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.58441548
27PCGF2_27294783_Chip-Seq_ESCs_Mouse1.54959640
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51383102
29RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50853540
30SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.50754997
31STAT3_23295773_ChIP-Seq_U87_Human1.50630861
32* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.49235180
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.49011047
34ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.48173932
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48079388
36AHR_22903824_ChIP-Seq_MCF-7_Human1.47909265
37EZH2_18974828_ChIP-Seq_MESCs_Mouse1.47199619
38RNF2_18974828_ChIP-Seq_MESCs_Mouse1.47199619
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45820531
40ARNT_22903824_ChIP-Seq_MCF-7_Human1.44688314
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.43200499
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42864823
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42747777
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.41668682
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.41433910
46MTF2_20144788_ChIP-Seq_MESCs_Mouse1.40926444
47RNF2_27304074_Chip-Seq_ESCs_Mouse1.40261048
48RUNX_20019798_ChIP-Seq_JUKART_Human1.38886376
49RNF2_27304074_Chip-Seq_NSC_Mouse1.38021774
50TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.37888020
51* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.37322481
52SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36837125
53CBP_20019798_ChIP-Seq_JUKART_Human1.35549909
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35549909
55EP300_21415370_ChIP-Seq_HL-1_Mouse1.35451160
56WT1_25993318_ChIP-Seq_PODOCYTE_Human1.34988407
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34537381
58CTNNB1_20460455_ChIP-Seq_HCT116_Human1.32777701
59* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.32121603
60* TCF4_23295773_ChIP-Seq_U87_Human1.31943665
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.31002697
62SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.30127202
63PRDM14_20953172_ChIP-Seq_ESCs_Human1.29512779
64TCF4_18268006_ChIP-ChIP_LS174T_Human1.29288589
65EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28971040
66RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.28820997
67ISL1_27105846_Chip-Seq_CPCs_Mouse1.28530098
68* AR_19668381_ChIP-Seq_PC3_Human1.27490534
69EZH2_27294783_Chip-Seq_NPCs_Mouse1.27389565
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26820567
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26820567
72MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26660408
73SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.26188646
74* RARB_27405468_Chip-Seq_BRAIN_Mouse1.25607651
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.24600325
76* RUNX2_22187159_ChIP-Seq_PCA_Human1.24544866
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.24340688
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.24149610
79P300_19829295_ChIP-Seq_ESCs_Human1.23598979
80SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.23504737
81TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23240227
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23152709
83TAF15_26573619_Chip-Seq_HEK293_Human1.22225032
84TCF4_22108803_ChIP-Seq_LS180_Human1.20937653
85SMAD3_21741376_ChIP-Seq_EPCs_Human1.20506867
86* SOX2_21211035_ChIP-Seq_LN229_Gbm1.20387130
87CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19808138
88FLI1_21867929_ChIP-Seq_TH2_Mouse1.19055903
89KDM2B_26808549_Chip-Seq_REH_Human1.18992530
90EZH2_27304074_Chip-Seq_ESCs_Mouse1.18719289
91SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.18268661
92P53_22387025_ChIP-Seq_ESCs_Mouse1.17772636
93SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.16972593
94TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14469823
95E2F1_18555785_Chip-Seq_ESCs_Mouse1.13518447
96EED_16625203_ChIP-ChIP_MESCs_Mouse1.13005530
97CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.12392653
98JARID2_20075857_ChIP-Seq_MESCs_Mouse1.12356986
99CTBP2_25329375_ChIP-Seq_LNCAP_Human1.11310148
100FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.10375131
101HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10091189
102TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09810384
103BCAT_22108803_ChIP-Seq_LS180_Human1.09110147
104ZFP57_27257070_Chip-Seq_ESCs_Mouse1.08725399
105EZH2_27294783_Chip-Seq_ESCs_Mouse1.08704866
106SMAD4_21741376_ChIP-Seq_EPCs_Human1.07962628
107WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.07759034
108SUZ12_27294783_Chip-Seq_ESCs_Mouse1.07537884
109FUS_26573619_Chip-Seq_HEK293_Human1.06611527
110EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06171614
111OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06095596
112HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05788613
113NR3C1_23031785_ChIP-Seq_PC12_Mouse1.05477176
114EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.05180294
115NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04209357
116ESR1_20079471_ChIP-ChIP_T-47D_Human1.04039765
117MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03956125
118NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.03295523
119* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03183852
120AR_25329375_ChIP-Seq_VCAP_Human1.03072256
121* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.02948935
122TBL1_22424771_ChIP-Seq_293T_Human1.02727789
123* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02720627
124MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02462405
125TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.01148279
126CMYC_18555785_Chip-Seq_ESCs_Mouse1.00967701
127GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00815545
128KDM2B_26808549_Chip-Seq_K562_Human1.00619837
129KDM2B_26808549_Chip-Seq_JURKAT_Human1.00238330
130NANOG_18555785_Chip-Seq_ESCs_Mouse1.00012150
131SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00004092
132* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99314332
133SMAD3_21741376_ChIP-Seq_HESCs_Human0.99250986
134KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.99189421
135CRX_20693478_ChIP-Seq_RETINA_Mouse0.98490623
136KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.98420893
137KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98330272
138ZNF274_21170338_ChIP-Seq_K562_Hela0.98268333
139IRF1_19129219_ChIP-ChIP_H3396_Human0.98143962
140STAT3_18555785_Chip-Seq_ESCs_Mouse0.97784837
141SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97291841
142STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97191377
143* FOXA2_19822575_ChIP-Seq_HepG2_Human0.97114682
144REST_21632747_ChIP-Seq_MESCs_Mouse0.96688059
145NANOG_19829295_ChIP-Seq_ESCs_Human0.96663016

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.94378325
2MP0005551_abnormal_eye_electrophysiolog3.81600021
3MP0006072_abnormal_retinal_apoptosis2.92543440
4MP0004859_abnormal_synaptic_plasticity2.74029835
5MP0003787_abnormal_imprinting2.64526919
6MP0005253_abnormal_eye_physiology2.62441102
7MP0003045_fibrosis2.49195131
8MP0003195_calcinosis2.31099598
9MP0002102_abnormal_ear_morphology2.30688775
10MP0005409_darkened_coat_color2.18774852
11MP0006292_abnormal_olfactory_placode2.13447895
12MP0009780_abnormal_chondrocyte_physiolo2.12441238
13MP0003950_abnormal_plasma_membrane1.99811853
14MP0004270_analgesia1.99654650
15MP0002234_abnormal_pharynx_morphology1.91027001
16MP0002009_preneoplasia1.90514965
17MP0003011_delayed_dark_adaptation1.89225070
18MP0004142_abnormal_muscle_tone1.87685893
19MP0002638_abnormal_pupillary_reflex1.87564185
20MP0001968_abnormal_touch/_nociception1.86921765
21MP0001299_abnormal_eye_distance/1.85592147
22MP0005646_abnormal_pituitary_gland1.81691506
23MP0003635_abnormal_synaptic_transmissio1.78988851
24MP0001486_abnormal_startle_reflex1.74255033
25MP0005423_abnormal_somatic_nervous1.70077898
26MP0008961_abnormal_basal_metabolism1.64791148
27MP0005645_abnormal_hypothalamus_physiol1.63635494
28MP0002166_altered_tumor_susceptibility1.61521747
29MP0005174_abnormal_tail_pigmentation1.59821306
30MP0005195_abnormal_posterior_eye1.57562183
31MP0004233_abnormal_muscle_weight1.57238262
32MP0002837_dystrophic_cardiac_calcinosis1.55259493
33MP0009046_muscle_twitch1.51717382
34MP0003646_muscle_fatigue1.50671405
35MP0005076_abnormal_cell_differentiation1.47794776
36MP0003300_gastrointestinal_ulcer1.46296547
37MP0008995_early_reproductive_senescence1.43790613
38MP0004133_heterotaxia1.43506495
39MP0005391_vision/eye_phenotype1.43336423
40MP0008569_lethality_at_weaning1.41496154
41MP0004145_abnormal_muscle_electrophysio1.37339065
42MP0004215_abnormal_myocardial_fiber1.37036217
43MP0003890_abnormal_embryonic-extraembry1.36371270
44MP0002736_abnormal_nociception_after1.35585734
45MP0001324_abnormal_eye_pigmentation1.32624878
46MP0002735_abnormal_chemical_nociception1.31049448
47MP0002108_abnormal_muscle_morphology1.30888994
48MP0000778_abnormal_nervous_system1.30123372
49MP0003121_genomic_imprinting1.29261805
50MP0004185_abnormal_adipocyte_glucose1.29073237
51MP0004130_abnormal_muscle_cell1.28805097
52MP0006276_abnormal_autonomic_nervous1.28762749
53MP0002876_abnormal_thyroid_physiology1.28583731
54MP0000751_myopathy1.27752123
55MP0001485_abnormal_pinna_reflex1.27325818
56MP0003283_abnormal_digestive_organ1.26235315
57MP0002063_abnormal_learning/memory/cond1.23740053
58MP0003880_abnormal_central_pattern1.23698167
59MP0002229_neurodegeneration1.21378864
60MP0002090_abnormal_vision1.21133421
61MP0001188_hyperpigmentation1.20255747
62MP0001986_abnormal_taste_sensitivity1.18783723
63MP0002572_abnormal_emotion/affect_behav1.18557536
64MP0004885_abnormal_endolymph1.18534660
65MP0000733_abnormal_muscle_development1.17534898
66MP0005187_abnormal_penis_morphology1.17135536
67MP0009745_abnormal_behavioral_response1.16792893
68MP0002882_abnormal_neuron_morphology1.16519668
69MP0004742_abnormal_vestibular_system1.15713814
70MP0003935_abnormal_craniofacial_develop1.15527513
71MP0002064_seizures1.15325894
72MP0003122_maternal_imprinting1.15079670
73MP0001440_abnormal_grooming_behavior1.14750584
74MP0001529_abnormal_vocalization1.12134278
75MP0002163_abnormal_gland_morphology1.11264826
76MP0001905_abnormal_dopamine_level1.10680058
77MP0001970_abnormal_pain_threshold1.09672610
78MP0001501_abnormal_sleep_pattern1.08800512
79MP0010630_abnormal_cardiac_muscle1.08488320
80MP0005389_reproductive_system_phenotype1.07496939
81MP0008877_abnormal_DNA_methylation1.05601525
82MP0001502_abnormal_circadian_rhythm1.05156020
83MP0005386_behavior/neurological_phenoty1.04650921
84MP0004924_abnormal_behavior1.04650921
85MP0002733_abnormal_thermal_nociception1.04223461
86MP0004087_abnormal_muscle_fiber1.03929723
87MP0002751_abnormal_autonomic_nervous1.02948957
88MP0000003_abnormal_adipose_tissue1.02272141
89MP0002697_abnormal_eye_size1.01784602
90MP0002160_abnormal_reproductive_system1.01696607
91MP0002938_white_spotting1.01620344
92MP0003938_abnormal_ear_development1.00993418
93MP0002909_abnormal_adrenal_gland1.00162012
94MP0002272_abnormal_nervous_system0.99549614
95MP0002067_abnormal_sensory_capabilities0.98640101
96MP0004085_abnormal_heartbeat0.98381670
97MP0005248_abnormal_Harderian_gland0.97933963
98MP0000428_abnormal_craniofacial_morphol0.97364897
99MP0005666_abnormal_adipose_tissue0.96676110
100MP0002006_tumorigenesis0.96257291
101MP0009703_decreased_birth_body0.94466743
102MP0008057_abnormal_DNA_replication0.94463768
103MP0005379_endocrine/exocrine_gland_phen0.94131126
104MP0008872_abnormal_physiological_respon0.94077032
105MP0005375_adipose_tissue_phenotype0.93947897
106MP0002752_abnormal_somatic_nervous0.92381644
107MP0004043_abnormal_pH_regulation0.91491705
108MP0005220_abnormal_exocrine_pancreas0.89595006
109MP0003137_abnormal_impulse_conducting0.88468843
110MP0002152_abnormal_brain_morphology0.87615109
111MP0003385_abnormal_body_wall0.87082826
112MP0003937_abnormal_limbs/digits/tail_de0.86462070
113MP0005503_abnormal_tendon_morphology0.84116870
114MP0002095_abnormal_skin_pigmentation0.83851805
115MP0002184_abnormal_innervation0.83361305
116MP0010386_abnormal_urinary_bladder0.82005716
117MP0001984_abnormal_olfaction0.81836796
118MP0002168_other_aberrant_phenotype0.81366063
119MP0000920_abnormal_myelination0.81349783
120MP0008775_abnormal_heart_ventricle0.80927629
121MP0000049_abnormal_middle_ear0.80319729
122MP0001919_abnormal_reproductive_system0.80063604
123MP0002557_abnormal_social/conspecific_i0.79801818
124MP0002925_abnormal_cardiovascular_devel0.79789115
125MP0005620_abnormal_muscle_contractility0.79689199
126MP0003633_abnormal_nervous_system0.79406008
127MP0002928_abnormal_bile_duct0.79076041
128MP0005075_abnormal_melanosome_morpholog0.78656235
129MP0000026_abnormal_inner_ear0.77599703
130MP0002734_abnormal_mechanical_nocicepti0.77328094
131MP0000383_abnormal_hair_follicle0.77184736
132MP0002693_abnormal_pancreas_physiology0.76900044
133MP0001944_abnormal_pancreas_morphology0.76849657
134MP0000631_abnormal_neuroendocrine_gland0.76827397
135MP0003119_abnormal_digestive_system0.76802358
136MP0000759_abnormal_skeletal_muscle0.76126807
137MP0003861_abnormal_nervous_system0.75191529
138MP0002277_abnormal_respiratory_mucosa0.75188948
139MP0003567_abnormal_fetal_cardiomyocyte0.74939786
140MP0004036_abnormal_muscle_relaxation0.73960424
141MP0000372_irregular_coat_pigmentation0.73231937
142MP0004084_abnormal_cardiac_muscle0.72782344
143MP0001661_extended_life_span0.72762781
144MP0003091_abnormal_cell_migration0.72680550
145MP0010678_abnormal_skin_adnexa0.72416628
146MP0005670_abnormal_white_adipose0.72322216
147MP0005623_abnormal_meninges_morphology0.72056118
148MP0000015_abnormal_ear_pigmentation0.71983744
149MP0000955_abnormal_spinal_cord0.71842598
150MP0001963_abnormal_hearing_physiology0.71735158
151MP0000427_abnormal_hair_cycle0.71187571
152MP0000266_abnormal_heart_morphology0.71037419
153MP0004134_abnormal_chest_morphology0.71018922
154MP0002971_abnormal_brown_adipose0.70052096
155MP0004811_abnormal_neuron_physiology0.69626987
156MP0001784_abnormal_fluid_regulation0.69068135
157MP0005369_muscle_phenotype0.68881676

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)5.14818908
2Abnormality of the fingertips (HP:0001211)4.14418023
3Central scotoma (HP:0000603)3.88066420
4Pancreatic cysts (HP:0001737)3.86241036
5Bony spicule pigmentary retinopathy (HP:0007737)3.79013488
6Hyperventilation (HP:0002883)3.74517028
7Macroorchidism (HP:0000053)3.66647319
8Pancreatic fibrosis (HP:0100732)3.51840704
9True hermaphroditism (HP:0010459)3.38951659
10Nephronophthisis (HP:0000090)3.26976310
11Scotoma (HP:0000575)3.21288383
12Chorioretinal atrophy (HP:0000533)3.19531097
13Abnormality of midbrain morphology (HP:0002418)3.16528665
14Molar tooth sign on MRI (HP:0002419)3.16528665
15Volvulus (HP:0002580)3.16377937
16Dyschromatopsia (HP:0007641)3.13008592
17Abnormality of macular pigmentation (HP:0008002)2.96683439
18Abnormality of the renal medulla (HP:0100957)2.92720295
19Pigmentary retinal degeneration (HP:0001146)2.88801755
20Short 4th metacarpal (HP:0010044)2.86208705
21Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.86208705
22Medial flaring of the eyebrow (HP:0010747)2.85727805
23Narrow palate (HP:0000189)2.85338124
24Abnormality of the renal cortex (HP:0011035)2.82110756
25Genetic anticipation (HP:0003743)2.80232516
26Hypothermia (HP:0002045)2.73936271
27Abnormal rod and cone electroretinograms (HP:0008323)2.69819759
28Long eyelashes (HP:0000527)2.66275529
29Midline defect of the nose (HP:0004122)2.61228808
30Trigonocephaly (HP:0000243)2.60094820
31Abnormality of the nasal septum (HP:0000419)2.59900269
32Absent rod-and cone-mediated responses on ERG (HP:0007688)2.52043477
33Limb dystonia (HP:0002451)2.51893616
34Aqueductal stenosis (HP:0002410)2.48307483
35Protruding tongue (HP:0010808)2.46467340
36Febrile seizures (HP:0002373)2.46228504
37Neoplasm of the adrenal cortex (HP:0100641)2.42550225
38Chronic hepatic failure (HP:0100626)2.41309694
39Lip pit (HP:0100267)2.39739747
40Widely spaced teeth (HP:0000687)2.36453459
41Heterotopia (HP:0002282)2.32244806
42Pendular nystagmus (HP:0012043)2.31996492
43Gait imbalance (HP:0002141)2.30764120
44Obsessive-compulsive behavior (HP:0000722)2.27540215
45Cystic liver disease (HP:0006706)2.26837754
46Focal motor seizures (HP:0011153)2.26499107
47Hemiparesis (HP:0001269)2.26360435
48Truncal obesity (HP:0001956)2.24413404
49Stomach cancer (HP:0012126)2.23457998
50Fair hair (HP:0002286)2.23126644
51Dysmetric saccades (HP:0000641)2.21937607
52Decreased central vision (HP:0007663)2.19957644
53Attenuation of retinal blood vessels (HP:0007843)2.19670147
54Progressive cerebellar ataxia (HP:0002073)2.17927945
55Atonic seizures (HP:0010819)2.17614832
56Decreased circulating renin level (HP:0003351)2.13566096
57Dialeptic seizures (HP:0011146)2.12811043
58Aplasia/Hypoplasia of the tibia (HP:0005772)2.11581431
59Excessive salivation (HP:0003781)2.11172484
60Drooling (HP:0002307)2.11172484
61Methylmalonic acidemia (HP:0002912)2.10929770
62Depressed nasal tip (HP:0000437)2.10218762
63Genital tract atresia (HP:0001827)2.08281181
64Type II diabetes mellitus (HP:0005978)2.08197063
65Congenital primary aphakia (HP:0007707)2.07032289
66Abnormality of the 4th metacarpal (HP:0010012)2.05013799
67Epileptic encephalopathy (HP:0200134)2.04547633
68Type II lissencephaly (HP:0007260)2.02867614
69Broad-based gait (HP:0002136)2.00737500
70Agitation (HP:0000713)2.00211524
71Renal cortical cysts (HP:0000803)1.99909316
72Truncal ataxia (HP:0002078)1.99435900
73Vaginal atresia (HP:0000148)1.97853730
74Abnormality of the labia minora (HP:0012880)1.97711423
75Poor coordination (HP:0002370)1.96804500
76Nephrogenic diabetes insipidus (HP:0009806)1.95831944
77Neonatal hypoglycemia (HP:0001998)1.95319883
78Anal stenosis (HP:0002025)1.94403836
79Vitreoretinal degeneration (HP:0000655)1.93565158
80Hypoplastic ischia (HP:0003175)1.92307227
81Action tremor (HP:0002345)1.92146785
82Abolished electroretinogram (ERG) (HP:0000550)1.91917237
83Supernumerary ribs (HP:0005815)1.91825620
84Anterior segment dysgenesis (HP:0007700)1.91336955
85Lissencephaly (HP:0001339)1.91103144
86Polydipsia (HP:0001959)1.90880507
87Abnormal drinking behavior (HP:0030082)1.90880507
88Tubular atrophy (HP:0000092)1.90768833
89Abnormal delayed hypersensitivity skin test (HP:0002963)1.90739433
90Cupped ear (HP:0000378)1.90581478
91Male pseudohermaphroditism (HP:0000037)1.90316952
92Furrowed tongue (HP:0000221)1.89003479
93Epileptiform EEG discharges (HP:0011182)1.88731587
94Macular degeneration (HP:0000608)1.88263150
95Hepatoblastoma (HP:0002884)1.88064836
96Broad metatarsal (HP:0001783)1.88027076
97Aplasia/Hypoplasia of the tongue (HP:0010295)1.84869982
98Urinary bladder sphincter dysfunction (HP:0002839)1.84133371
99Anencephaly (HP:0002323)1.83962993
100Urethral obstruction (HP:0000796)1.83756473
101Hypsarrhythmia (HP:0002521)1.83742196
102Papillary thyroid carcinoma (HP:0002895)1.83311303
103EEG with generalized epileptiform discharges (HP:0011198)1.82948589
104Absent speech (HP:0001344)1.82514669
105Inability to walk (HP:0002540)1.80443067
106Gaze-evoked nystagmus (HP:0000640)1.80240502
107Progressive inability to walk (HP:0002505)1.80146462
108Pachygyria (HP:0001302)1.79960499
109Neoplasm of the heart (HP:0100544)1.79761924
110Hypoplasia of the maxilla (HP:0000327)1.79240140
111Focal seizures (HP:0007359)1.79110093
112Sclerocornea (HP:0000647)1.78892951
113Small hand (HP:0200055)1.75419309
114Abnormality of T cell number (HP:0011839)1.75043442
115Thick eyebrow (HP:0000574)1.74826579
116Shallow orbits (HP:0000586)1.74472922
117Thyroiditis (HP:0100646)1.74002192
118Anteriorly placed anus (HP:0001545)1.73729321
119Abnormality of the parietal bone (HP:0002696)1.73583680
120Increased corneal curvature (HP:0100692)1.72928862
121Keratoconus (HP:0000563)1.72928862
122Abnormality of secondary sexual hair (HP:0009888)1.72511651
123Abnormality of the axillary hair (HP:0100134)1.72511651
124Hypoplastic labia majora (HP:0000059)1.72368150
125Abnormality of vitamin B metabolism (HP:0004340)1.72299552
126Prolonged QT interval (HP:0001657)1.71943927
127Generalized hypopigmentation of hair (HP:0011358)1.71752297
128Photophobia (HP:0000613)1.71126381
129Sparse lateral eyebrow (HP:0005338)1.70197132
130Congenital hepatic fibrosis (HP:0002612)1.69899926
131Optic nerve hypoplasia (HP:0000609)1.69703678
132Dysdiadochokinesis (HP:0002075)1.69613010
133Aortic aneurysm (HP:0004942)1.69391597
134Hemiplegia (HP:0002301)1.68397806
135Hypoplastic iliac wings (HP:0002866)1.68359488
136Absence seizures (HP:0002121)1.68186346
137Specific learning disability (HP:0001328)1.68123565
138Postaxial hand polydactyly (HP:0001162)1.68113631
139Intestinal atresia (HP:0011100)1.67712228
140Clumsiness (HP:0002312)1.67325734
141Open mouth (HP:0000194)1.67241800
142Birth length less than 3rd percentile (HP:0003561)1.67031554
143Smooth philtrum (HP:0000319)1.66972384
144Abnormality of the ischium (HP:0003174)1.66691499
145Elfin facies (HP:0004428)1.66675115
146Absent frontal sinuses (HP:0002688)1.66276897
147Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.66191846
148Cone-rod dystrophy (HP:0000548)1.65622810
149Prominent nose (HP:0000448)1.65180203
150Choroideremia (HP:0001139)1.65152067
151Polyphagia (HP:0002591)1.64882576
152Hyporeflexia of lower limbs (HP:0002600)1.63600886
153Cerebral aneurysm (HP:0004944)1.63547512
154Autoimmune thrombocytopenia (HP:0001973)1.62295054
155Large for gestational age (HP:0001520)1.61800954
156Hyperacusis (HP:0010780)1.61728777
157Abnormality of the labia majora (HP:0012881)1.60149970
158Renovascular hypertension (HP:0100817)1.57420996
159Deep philtrum (HP:0002002)1.56831582
160Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.55645880
161Supernumerary bones of the axial skeleton (HP:0009144)1.55607094
162Severe visual impairment (HP:0001141)1.55397814
163Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.55335262
164Tapered finger (HP:0001182)1.54101861
165Exotropia (HP:0000577)1.51988982
166Neoplasm of the oral cavity (HP:0100649)1.50483370
167Tented upper lip vermilion (HP:0010804)1.50148816
168Low anterior hairline (HP:0000294)1.49809415
169Blue irides (HP:0000635)1.48003271
170Abnormality of incisor morphology (HP:0011063)1.47034470
171Transitional cell carcinoma of the bladder (HP:0006740)1.46704833
172Acute lymphatic leukemia (HP:0006721)1.45201537
173Oligodactyly (hands) (HP:0001180)1.44417182
174Lower limb amyotrophy (HP:0007210)1.44126003
175Atrial fibrillation (HP:0005110)1.43531692

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CAMK1G3.72409191
2CDK123.43724722
3CAMK1D3.24558354
4TLK13.15764496
5CASK2.90463370
6BRD42.53977928
7WNK32.37155102
8LATS12.29468375
9FGFR22.18702648
10BMPR1B2.04959753
11SIK21.91051274
12PINK11.90190469
13DMPK1.86729245
14WNK11.77584077
15SIK11.74256178
16ADRBK21.71544914
17SGK31.70521265
18MAP4K21.68097482
19INSRR1.67015924
20ICK1.66665080
21SGK21.63898224
22ACVR1B1.58855325
23MAP3K41.50181630
24OXSR11.46744191
25FGFR31.45644191
26PRKD31.44247558
27MARK21.40229387
28CAMKK21.38697889
29PNCK1.36895090
30MAP3K71.35003265
31AKT31.32376850
32RIPK11.31571365
33NLK1.29230467
34NTRK21.25920583
35NTRK31.25539151
36MAP3K101.23771094
37PDGFRB1.22593011
38CDK91.20335052
39MAP2K71.17881824
40PRKCH1.17680727
41MKNK21.15722737
42SGK2231.14944624
43SGK4941.14944624
44NUAK11.14746539
45STK381.13903535
46HIPK21.13003756
47FRK1.09317067
48JAK11.08233988
49PRKD21.08099211
50MAP2K41.07138708
51STK391.06596079
52SGK11.04542763
53ZAK1.01874300
54PLK21.00344428
55TNIK1.00085726
56EPHA40.99803756
57PRKCG0.99072129
58PRKAA20.98748978
59STK110.98268237
60MTOR0.97441695
61CDC42BPA0.96638510
62PIK3CA0.95230489
63DYRK20.95208030
64GRK10.93541406
65WNK40.92528279
66TTN0.91802098
67CAMK40.90218349
68PDGFRA0.88767295
69TAOK30.86836573
70TRIM280.86694990
71PKN10.82470140
72CSNK1G10.79507362
73RET0.78525934
74CAMK10.78525167
75PAK60.77999557
76PRKAA10.77704242
77ITK0.77479203
78CSNK1G20.76960034
79BCR0.76942647
80ADRBK10.76254023
81MAPKAPK50.76095300
82MAPK70.76034744
83ERBB30.75050862
84PHKG10.74168016
85PHKG20.74168016
86STK30.74056419
87TEC0.74023991
88PRKCE0.73626422
89MAP3K130.70938712
90TYRO30.70872645
91ERBB20.70844683
92PRKCQ0.69351643
93MAPK100.68083653
94CSNK1A1L0.68033475
95CDK30.67027405
96EPHB10.65620448
97MAP4K10.64801142
98STK40.64735794
99PRKD10.63735012
100CDK190.62975193
101PTK2B0.62694343
102FGFR10.60935380
103RPS6KA30.59731800
104CDK60.59398306
105CSNK1D0.59050836
106MAPK130.58849150
107GRK70.58105560
108MINK10.57606034
109PDK10.57441963
110CAMK2A0.57101838
111PAK30.54917919
112DYRK1A0.54610772
113TXK0.54467430
114GSK3B0.54083514
115CDK50.53151984
116EPHA30.53112239
117MAPK80.51660883
118EEF2K0.51343466
119CSNK1G30.51284376
120RIPK40.50726961
121HCK0.50499237
122IRAK10.50363044
123FYN0.49489161
124PRPF4B0.49392492
125MELK0.48692872
126FES0.48665563
127MAPK140.48172045
128RPS6KA50.48050319
129KIT0.47516700
130PRKDC0.47486419
131ATM0.47485271
132TNK20.47350865
133MARK10.47210274
134DAPK20.46396796
135CLK10.45464418
136MAPK120.45098548
137PRKG10.45077955
138SYK0.44640121
139PRKCZ0.44339315
140PRKACA0.43069217
141GRK50.42975715
142PRKCB0.42865767
143MAP2K60.41767500
144MAP3K90.40719965
145CAMKK10.40305069
146OBSCN0.40157304
147PIK3CG0.39795758
148BLK0.38670936
149CAMK2B0.37665098
150FER0.35231773
151TAF10.34906664

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047443.92381067
2Maturity onset diabetes of the young_Homo sapiens_hsa049502.52616674
3Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.14420290
4Caffeine metabolism_Homo sapiens_hsa002322.04504484
5Linoleic acid metabolism_Homo sapiens_hsa005912.00877311
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.80615363
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.66311097
8alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.61168622
9Circadian entrainment_Homo sapiens_hsa047131.59691452
10Long-term potentiation_Homo sapiens_hsa047201.57962853
11Lysine degradation_Homo sapiens_hsa003101.57335201
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55496824
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.54594544
14Dorso-ventral axis formation_Homo sapiens_hsa043201.51776457
15Butanoate metabolism_Homo sapiens_hsa006501.51517915
16Type II diabetes mellitus_Homo sapiens_hsa049301.50890384
17Nicotine addiction_Homo sapiens_hsa050331.50280586
18Glutamatergic synapse_Homo sapiens_hsa047241.50221404
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.49627581
20Renin secretion_Homo sapiens_hsa049241.48409357
21Morphine addiction_Homo sapiens_hsa050321.45322942
22Phosphatidylinositol signaling system_Homo sapiens_hsa040701.42404129
23Salivary secretion_Homo sapiens_hsa049701.40675626
24Insulin secretion_Homo sapiens_hsa049111.39673046
25Dilated cardiomyopathy_Homo sapiens_hsa054141.39181589
26Selenocompound metabolism_Homo sapiens_hsa004501.37914998
27Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.36872463
28Olfactory transduction_Homo sapiens_hsa047401.35740566
29Ether lipid metabolism_Homo sapiens_hsa005651.35196994
30GABAergic synapse_Homo sapiens_hsa047271.34966413
31Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.33882617
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33450620
33cGMP-PKG signaling pathway_Homo sapiens_hsa040221.32697952
34Basal transcription factors_Homo sapiens_hsa030221.30512753
35Thyroid hormone signaling pathway_Homo sapiens_hsa049191.28497512
36Gastric acid secretion_Homo sapiens_hsa049711.28324856
37Cholinergic synapse_Homo sapiens_hsa047251.27919614
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.27105489
39Oxytocin signaling pathway_Homo sapiens_hsa049211.25332958
40cAMP signaling pathway_Homo sapiens_hsa040241.24622783
41Amphetamine addiction_Homo sapiens_hsa050311.19585061
42Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.18516515
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.17774462
44Dopaminergic synapse_Homo sapiens_hsa047281.17142302
45Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.16069359
46mTOR signaling pathway_Homo sapiens_hsa041501.09586750
47Circadian rhythm_Homo sapiens_hsa047101.09301510
48Glioma_Homo sapiens_hsa052141.08302393
49Protein export_Homo sapiens_hsa030601.08116197
50GnRH signaling pathway_Homo sapiens_hsa049121.06874213
51Regulation of autophagy_Homo sapiens_hsa041401.05319855
52Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.05032286
53Calcium signaling pathway_Homo sapiens_hsa040201.04245856
54Choline metabolism in cancer_Homo sapiens_hsa052311.02829751
55Long-term depression_Homo sapiens_hsa047301.02570181
56Tryptophan metabolism_Homo sapiens_hsa003801.02461133
57T cell receptor signaling pathway_Homo sapiens_hsa046601.01871070
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01581040
59ErbB signaling pathway_Homo sapiens_hsa040121.01087091
60Fanconi anemia pathway_Homo sapiens_hsa034601.00171370
61Wnt signaling pathway_Homo sapiens_hsa043100.99838329
62Axon guidance_Homo sapiens_hsa043600.98450826
63Adherens junction_Homo sapiens_hsa045200.98349177
64Longevity regulating pathway - mammal_Homo sapiens_hsa042110.98286302
65Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.98118140
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.95687871
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.95087950
68Estrogen signaling pathway_Homo sapiens_hsa049150.94774450
69Glucagon signaling pathway_Homo sapiens_hsa049220.94542701
70Carbohydrate digestion and absorption_Homo sapiens_hsa049730.92485519
71Inositol phosphate metabolism_Homo sapiens_hsa005620.91891371
72MAPK signaling pathway_Homo sapiens_hsa040100.91858952
73B cell receptor signaling pathway_Homo sapiens_hsa046620.90831807
74Type I diabetes mellitus_Homo sapiens_hsa049400.90826947
75Cocaine addiction_Homo sapiens_hsa050300.88923538
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.88746637
77Non-small cell lung cancer_Homo sapiens_hsa052230.88331249
78Melanogenesis_Homo sapiens_hsa049160.88113247
79Insulin resistance_Homo sapiens_hsa049310.87699067
80Renal cell carcinoma_Homo sapiens_hsa052110.86716145
81Primary immunodeficiency_Homo sapiens_hsa053400.86197418
82Homologous recombination_Homo sapiens_hsa034400.85958642
83Endometrial cancer_Homo sapiens_hsa052130.85764457
84Cardiac muscle contraction_Homo sapiens_hsa042600.85451748
85RNA degradation_Homo sapiens_hsa030180.84773407
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83895430
87Serotonergic synapse_Homo sapiens_hsa047260.83774996
88Taste transduction_Homo sapiens_hsa047420.83541243
89Chronic myeloid leukemia_Homo sapiens_hsa052200.82763750
90Retinol metabolism_Homo sapiens_hsa008300.82091331
91Prostate cancer_Homo sapiens_hsa052150.79108526
92MicroRNAs in cancer_Homo sapiens_hsa052060.78872283
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.78849867
94Basal cell carcinoma_Homo sapiens_hsa052170.77955988
95Alcoholism_Homo sapiens_hsa050340.77069692
96Pancreatic secretion_Homo sapiens_hsa049720.76703986
97FoxO signaling pathway_Homo sapiens_hsa040680.76580896
98Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75530517
99AMPK signaling pathway_Homo sapiens_hsa041520.75483822
100Proteoglycans in cancer_Homo sapiens_hsa052050.74764777
101Platelet activation_Homo sapiens_hsa046110.74295444
102Focal adhesion_Homo sapiens_hsa045100.73956082
103Gap junction_Homo sapiens_hsa045400.73543245
104Nitrogen metabolism_Homo sapiens_hsa009100.72759308
105Pancreatic cancer_Homo sapiens_hsa052120.72058681
106Insulin signaling pathway_Homo sapiens_hsa049100.71901297
107Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71654236
108Colorectal cancer_Homo sapiens_hsa052100.71223949
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.70886709
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.70444246
111Steroid hormone biosynthesis_Homo sapiens_hsa001400.70307824
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.70172237
113African trypanosomiasis_Homo sapiens_hsa051430.70055022
114Thyroid hormone synthesis_Homo sapiens_hsa049180.70004140
115Rap1 signaling pathway_Homo sapiens_hsa040150.69953341
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69533442
117Transcriptional misregulation in cancer_Homo sapiens_hsa052020.69017633
118Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68573246
119Viral myocarditis_Homo sapiens_hsa054160.67948191
120Oxidative phosphorylation_Homo sapiens_hsa001900.67630508
121Chemokine signaling pathway_Homo sapiens_hsa040620.66042616
122Hedgehog signaling pathway_Homo sapiens_hsa043400.64909427
123Propanoate metabolism_Homo sapiens_hsa006400.64413145
124Notch signaling pathway_Homo sapiens_hsa043300.63598034
125Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.63446121
126Fatty acid biosynthesis_Homo sapiens_hsa000610.63206803
127ABC transporters_Homo sapiens_hsa020100.62773149
128Ovarian steroidogenesis_Homo sapiens_hsa049130.62631130
129Ras signaling pathway_Homo sapiens_hsa040140.62583813
130Systemic lupus erythematosus_Homo sapiens_hsa053220.61816115
131ECM-receptor interaction_Homo sapiens_hsa045120.61515965
132Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61108735
133Chemical carcinogenesis_Homo sapiens_hsa052040.60504895
134Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60027664
135Graft-versus-host disease_Homo sapiens_hsa053320.59574822
136RNA polymerase_Homo sapiens_hsa030200.55423470
137Peroxisome_Homo sapiens_hsa041460.52037243
138Prolactin signaling pathway_Homo sapiens_hsa049170.51642582
139Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51142246
140TGF-beta signaling pathway_Homo sapiens_hsa043500.50128884
141Parkinsons disease_Homo sapiens_hsa050120.49034686
142Melanoma_Homo sapiens_hsa052180.47677946
143Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.47188202
144Intestinal immune network for IgA production_Homo sapiens_hsa046720.45935429
145Glycerolipid metabolism_Homo sapiens_hsa005610.42715800
146Alzheimers disease_Homo sapiens_hsa050100.40115250
147Autoimmune thyroid disease_Homo sapiens_hsa053200.38412679
148Arachidonic acid metabolism_Homo sapiens_hsa005900.37885805
149Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36711944

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