TNS3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular visceral epithelial cell development (GO:0072015)5.87532316
2glomerular epithelial cell development (GO:0072310)5.49033053
3glomerular basement membrane development (GO:0032836)4.99907891
4cell adhesion mediated by integrin (GO:0033627)4.54284504
5apoptotic cell clearance (GO:0043277)4.04883240
6glycosphingolipid catabolic process (GO:0046479)3.87895657
7barbed-end actin filament capping (GO:0051016)3.80357332
8positive regulation of p38MAPK cascade (GO:1900745)3.67452000
9neuron projection extension involved in neuron projection guidance (GO:1902284)3.65697815
10axon extension involved in axon guidance (GO:0048846)3.65697815
11positive regulation of extracellular matrix organization (GO:1903055)3.63691127
12positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.62567449
13regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.51602982
14glycolipid catabolic process (GO:0019377)3.50922901
15wound healing, spreading of epidermal cells (GO:0035313)3.49602127
16regulation of cholesterol storage (GO:0010885)3.45393522
17skin morphogenesis (GO:0043589)3.44322608
18oligosaccharide catabolic process (GO:0009313)3.39914387
19regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.39400606
20renal filtration (GO:0097205)3.34767774
21vascular endothelial growth factor signaling pathway (GO:0038084)3.31371530
22positive regulation of SMAD protein import into nucleus (GO:0060391)3.31228787
23regulation of mononuclear cell migration (GO:0071675)3.30427049
24semaphorin-plexin signaling pathway (GO:0071526)3.29304067
25keratan sulfate catabolic process (GO:0042340)3.21989899
26endodermal cell differentiation (GO:0035987)3.21080865
27regulation of macrophage chemotaxis (GO:0010758)3.17482659
28pinocytosis (GO:0006907)3.16370124
29protein heterotrimerization (GO:0070208)3.08548836
30cellular response to thyroid hormone stimulus (GO:0097067)3.07618771
31protein localization to endosome (GO:0036010)3.06675487
32basement membrane organization (GO:0071711)3.06366405
33low-density lipoprotein particle clearance (GO:0034383)3.05413256
34regulation of SMAD protein import into nucleus (GO:0060390)3.04094340
35regulation of apoptotic cell clearance (GO:2000425)3.02732647
36ceramide catabolic process (GO:0046514)2.99439812
37platelet-derived growth factor receptor signaling pathway (GO:0048008)2.94693763
38cell migration involved in sprouting angiogenesis (GO:0002042)2.93504858
39cellular response to vitamin (GO:0071295)2.93345018
40hippo signaling (GO:0035329)2.93262459
41insulin-like growth factor receptor signaling pathway (GO:0048009)2.89269327
42collagen fibril organization (GO:0030199)2.85057326
43polarized epithelial cell differentiation (GO:0030859)2.81885111
44glomerular filtration (GO:0003094)2.78471276
45regulation of early endosome to late endosome transport (GO:2000641)2.77676064
46stress fiber assembly (GO:0043149)2.77636494
47NLS-bearing protein import into nucleus (GO:0006607)2.76995026
48mesodermal cell differentiation (GO:0048333)2.76648914
49substrate-dependent cell migration (GO:0006929)2.75521868
50positive regulation of catenin import into nucleus (GO:0035413)2.75437029
51modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.74091074
52positive regulation by organism of defense response of other organism involved in symbiotic interact2.74091074
53modulation by symbiont of host immune response (GO:0052553)2.74091074
54positive regulation by symbiont of host defense response (GO:0052509)2.74091074
55modulation by symbiont of host defense response (GO:0052031)2.74091074
56modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.74091074
57cellular response to vitamin D (GO:0071305)2.73854192
58cytoskeletal anchoring at plasma membrane (GO:0007016)2.73787210
59response to thyroid hormone (GO:0097066)2.73281460
60substrate adhesion-dependent cell spreading (GO:0034446)2.72190839
61hyaluronan catabolic process (GO:0030214)2.71981703
62adhesion of symbiont to host cell (GO:0044650)2.71861685
63virion attachment to host cell (GO:0019062)2.71861685
64regulation of p38MAPK cascade (GO:1900744)2.70186732
65positive regulation of receptor recycling (GO:0001921)2.69555805
66macroautophagy (GO:0016236)2.65411615
67epithelial cell-cell adhesion (GO:0090136)2.64782319
68regulation of cholesterol homeostasis (GO:2000188)2.64089547
69COPI coating of Golgi vesicle (GO:0048205)2.63835880
70Golgi transport vesicle coating (GO:0048200)2.63835880
71regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.63707648
72regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.62748656
73hemidesmosome assembly (GO:0031581)2.62128374
74planar cell polarity pathway involved in neural tube closure (GO:0090179)2.62017627
75positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.61825663
76membrane lipid catabolic process (GO:0046466)2.60292478
77branching involved in salivary gland morphogenesis (GO:0060445)2.59074618
78wound healing, spreading of cells (GO:0044319)2.59074344
79positive regulation of cholesterol efflux (GO:0010875)2.58272547
80epithelial cell differentiation involved in prostate gland development (GO:0060742)2.55828857
81cell-substrate junction assembly (GO:0007044)2.55258799
82collagen catabolic process (GO:0030574)2.54792099
83chondrocyte proliferation (GO:0035988)2.54049549
84collagen metabolic process (GO:0032963)2.53139566
85establishment of apical/basal cell polarity (GO:0035089)2.52448568
86positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.52325558
87plasma lipoprotein particle clearance (GO:0034381)2.51485501
88regulation of extracellular matrix disassembly (GO:0010715)2.51225382
89glial cell migration (GO:0008347)2.50910387
90regulation of interferon-beta biosynthetic process (GO:0045357)2.50574265
91regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.50099900
92craniofacial suture morphogenesis (GO:0097094)2.49043014
93multicellular organismal macromolecule metabolic process (GO:0044259)2.48899340
94multicellular organismal catabolic process (GO:0044243)2.48656521
95negative regulation of fatty acid transport (GO:2000192)2.48049266
96cell migration involved in heart development (GO:0060973)2.47782114
97coronary vasculature morphogenesis (GO:0060977)2.47687752
98decidualization (GO:0046697)2.47530045
99cortical actin cytoskeleton organization (GO:0030866)2.46744049
100regulation of extracellular matrix organization (GO:1903053)2.46608090
101sphingolipid catabolic process (GO:0030149)2.46475334
102negative regulation of smooth muscle cell migration (GO:0014912)2.44351696
103cellular response to interferon-alpha (GO:0035457)2.44007586
104regulation of catenin import into nucleus (GO:0035412)2.43370671
105response to fluid shear stress (GO:0034405)2.42758659
106cytoplasmic mRNA processing body assembly (GO:0033962)2.42230086
107adherens junction assembly (GO:0034333)2.41670676
108regulation of hippo signaling (GO:0035330)2.41328036
109cell proliferation involved in metanephros development (GO:0072203)2.41243154
110peptide catabolic process (GO:0043171)2.41121315
111positive regulation of endothelial cell apoptotic process (GO:2000353)2.40954979
112regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.40916765
113cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.40694979
114negative regulation of chondrocyte differentiation (GO:0032331)2.40617917
115dorsal/ventral axis specification (GO:0009950)2.40354940
116extracellular matrix disassembly (GO:0022617)2.38253870
117adhesion of symbiont to host (GO:0044406)2.37657412
118endocardial cushion development (GO:0003197)2.36977833
119glomerulus development (GO:0032835)2.36599953
120retina vasculature morphogenesis in camera-type eye (GO:0061299)2.36130740
121negative regulation of protein localization to plasma membrane (GO:1903077)2.36029028
122positive regulation of phagocytosis (GO:0050766)2.34467080
123blood vessel endothelial cell migration (GO:0043534)2.34306817
124multicellular organismal metabolic process (GO:0044236)2.34278751
125renal system development (GO:0072001)2.34049387
126regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.33482149
127amino sugar catabolic process (GO:0046348)2.33344830
128dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.33281622
129negative regulation of lipid transport (GO:0032369)2.33053538
130regulation of integrin activation (GO:0033623)2.30995388
131metanephric mesenchyme development (GO:0072075)2.30534962
132regulation of membrane protein ectodomain proteolysis (GO:0051043)2.29677474
133mannose metabolic process (GO:0006013)2.29437036
134positive regulation of cell adhesion mediated by integrin (GO:0033630)2.28684115
135chondroitin sulfate catabolic process (GO:0030207)2.27278601
136prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.27022533
137anatomical structure regression (GO:0060033)2.26556935
138surfactant homeostasis (GO:0043129)2.26476574
139vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.26436635
140membrane protein ectodomain proteolysis (GO:0006509)2.25520274
141protein retention in ER lumen (GO:0006621)2.25161056
142response to laminar fluid shear stress (GO:0034616)2.25071288
143fibroblast migration (GO:0010761)2.24834202
144regulation of cholesterol esterification (GO:0010872)2.24802855
145embryo implantation (GO:0007566)2.24568280
146regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.23290373
147regulation of integrin-mediated signaling pathway (GO:2001044)2.23097800
148cortical cytoskeleton organization (GO:0030865)2.23036420
149membrane raft organization (GO:0031579)2.22615676
150regulation of vitamin D biosynthetic process (GO:0060556)2.19193315
151positive regulation of sterol transport (GO:0032373)2.18163265
152positive regulation of cholesterol transport (GO:0032376)2.18163265
153regulation of vitamin metabolic process (GO:0030656)2.17994407
154negative regulation of fibrinolysis (GO:0051918)2.17775136
155positive regulation of triglyceride lipase activity (GO:0061365)2.16412265
156positive regulation of lipoprotein lipase activity (GO:0051006)2.16412265
157low-density lipoprotein particle remodeling (GO:0034374)2.16311388
158regulation of glucose import in response to insulin stimulus (GO:2001273)2.16274871
159eosinophil chemotaxis (GO:0048245)2.14705982
160maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.14107012

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human3.79170315
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.73943063
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.39263934
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.22078781
5NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.88610823
6RARG_19884340_ChIP-ChIP_MEFs_Mouse2.53012572
7CLOCK_20551151_ChIP-Seq_293T_Human2.43620236
8ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.36049259
9* ESR1_21235772_ChIP-Seq_MCF-7_Human2.20834405
10THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.19783431
11* SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.17829329
12STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.17101223
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.10658487
14* ESR2_21235772_ChIP-Seq_MCF-7_Human2.08184697
15* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.03170403
16TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.01849104
17PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.99822763
18WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.94706633
19FOXO3_23340844_ChIP-Seq_DLD1_Human1.90912578
20* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.88602297
21RXR_22158963_ChIP-Seq_LIVER_Mouse1.84934429
22* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.76766218
23WT1_19549856_ChIP-ChIP_CCG9911_Human1.74928538
24ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.73526852
25* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.72176311
26KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.69660552
27* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.66993205
28ELK3_25401928_ChIP-Seq_HUVEC_Human1.65219944
29SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.64338722
30BRD4_25478319_ChIP-Seq_HGPS_Human1.63894808
31CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.61909842
32* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.61807080
33P300_27058665_Chip-Seq_ZR-75-30cells_Human1.61582624
34KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.61096923
35KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.61096923
36KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.61096923
37KDM2B_26808549_Chip-Seq_SUP-B15_Human1.60582188
38* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.60342272
39PPARA_22158963_ChIP-Seq_LIVER_Mouse1.57752623
40* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.56583248
41GATA2_21666600_ChIP-Seq_HMVEC_Human1.56283248
42TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.55515401
43* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.53934513
44* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.53573088
45STAT6_21828071_ChIP-Seq_BEAS2B_Human1.52782030
46NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.52586630
47SALL4_18804426_ChIP-ChIP_XEN_Mouse1.51653234
48FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.47682438
49SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.46551577
50CJUN_26792858_Chip-Seq_BT549_Human1.46493714
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.46034524
52VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.43675446
53SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.42905444
54RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.41803472
55ZFP281_27345836_Chip-Seq_ESCs_Mouse1.41643867
56SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.41632414
57* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.41425065
58HIF1A_21447827_ChIP-Seq_MCF-7_Human1.39477796
59FOXM1_23109430_ChIP-Seq_U2OS_Human1.36483666
60SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.36475914
61SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.36475914
62KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.36238854
63IRF8_22096565_ChIP-ChIP_GC-B_Human1.35072452
64* KDM2B_26808549_Chip-Seq_DND41_Human1.34391459
65* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.33779741
66SALL1_21062744_ChIP-ChIP_HESCs_Human1.33685938
67IRF8_27001747_Chip-Seq_BMDM_Mouse1.33645081
68* EP300_21415370_ChIP-Seq_HL-1_Mouse1.31061043
69TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30995797
70* FOXA2_19822575_ChIP-Seq_HepG2_Human1.30913032
71* VDR_24787735_ChIP-Seq_THP-1_Human1.30851631
72KDM2B_26808549_Chip-Seq_K562_Human1.30712406
73TCF7_22412390_ChIP-Seq_EML_Mouse1.30543890
74NFIB_24661679_ChIP-Seq_LUNG_Mouse1.30164632
75* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.29912309
76BP1_19119308_ChIP-ChIP_Hs578T_Human1.29408600
77TP53_16413492_ChIP-PET_HCT116_Human1.29205761
78ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.28055310
79FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.27692186
80ZFP281_18757296_ChIP-ChIP_E14_Mouse1.26277348
81ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.26150632
82NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.25624106
83ZNF263_19887448_ChIP-Seq_K562_Human1.25270237
84MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.24853623
85HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.21709258
86CDX2_20551321_ChIP-Seq_CACO-2_Human1.20763498
87IRF8_21731497_ChIP-ChIP_J774_Mouse1.20348687
88KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.19719095
89POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.19349875
90RACK7_27058665_Chip-Seq_MCF-7_Human1.18461770
91FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.17617292
92SMC1_22415368_ChIP-Seq_MEFs_Mouse1.17152852
93TBX20_22328084_ChIP-Seq_HEART_Mouse1.15181840
94TBX20_22080862_ChIP-Seq_HEART_Mouse1.15181840
95JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15141574
96PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.14612651
97* ISL1_27105846_Chip-Seq_CPCs_Mouse1.13888207
98SOX2_27498859_Chip-Seq_STOMACH_Mouse1.13730723
99* SOX2_20726797_ChIP-Seq_SW620_Human1.13095104
100ESR1_20079471_ChIP-ChIP_T-47D_Human1.13058812
101TCF3_18692474_ChIP-Seq_MEFs_Mouse1.11976855
102UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.11942192
103NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11577178
104NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11577178
105LXR_22158963_ChIP-Seq_LIVER_Mouse1.11222310
106UBF1/2_26484160_Chip-Seq_HMECs_Human1.10197323
107* AHR_22903824_ChIP-Seq_MCF-7_Human1.10025126
108CDX2_19796622_ChIP-Seq_MESCs_Mouse1.09329544
109JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08853604
110KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08654019
111SPI1_23127762_ChIP-Seq_K562_Human1.07682650
112CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07089184
113TP53_22127205_ChIP-Seq_IMR90_Human1.06756711
114ESR1_15608294_ChIP-ChIP_MCF-7_Human1.06297234
115STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.05654256
116GATA6_25053715_ChIP-Seq_YYC3_Human1.04680720
117* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.04077918
118* VDR_24763502_ChIP-Seq_THP-1_Human1.04065945
119NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.03757907
120LXR_22292898_ChIP-Seq_THP-1_Human1.03415401
121* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.03394244
122P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01171338
123EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96929232
124* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96586740
125ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94519286
126GATA1_19941827_ChIP-Seq_MEL_Mouse0.93948873
127GATA1_19941826_ChIP-Seq_K562_Human0.93614100
128TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.92595407
129TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92166403
130PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.91792192

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.23897122
2MP0003705_abnormal_hypodermis_morpholog3.89906438
3MP0004272_abnormal_basement_membrane3.00841529
4MP0000569_abnormal_digit_pigmentation2.89669705
5MP0003191_abnormal_cellular_cholesterol2.79021552
6MP0002139_abnormal_hepatobiliary_system2.76873350
7MP0005623_abnormal_meninges_morphology2.73666216
8MP0003566_abnormal_cell_adhesion2.70073609
9MP0005257_abnormal_intraocular_pressure2.66563472
10MP0001958_emphysema2.50495832
11MP0005503_abnormal_tendon_morphology2.50421923
12MP0003300_gastrointestinal_ulcer2.48257959
13MP0005275_abnormal_skin_tensile2.34775286
14MP0005076_abnormal_cell_differentiation2.22005481
15MP0010352_gastrointestinal_tract_polyps2.20205491
16MP0000604_amyloidosis2.14340916
17MP0003172_abnormal_lysosome_physiology2.14106320
18MP0005058_abnormal_lysosome_morphology2.08712240
19MP0003279_aneurysm1.95975431
20MP0003283_abnormal_digestive_organ1.95191615
21MP0009278_abnormal_bone_marrow1.90686324
22MP0005023_abnormal_wound_healing1.86433736
23MP0000537_abnormal_urethra_morphology1.84256640
24MP0000343_altered_response_to1.84187327
25MP0000733_abnormal_muscle_development1.74756125
26* MP0003091_abnormal_cell_migration1.74273633
27MP0009384_cardiac_valve_regurgitation1.71197744
28MP0003329_amyloid_beta_deposits1.64774372
29MP0005451_abnormal_body_composition1.59100234
30MP0010307_abnormal_tumor_latency1.55650702
31MP0003303_peritoneal_inflammation1.52541487
32MP0000516_abnormal_urinary_system1.51523122
33MP0005367_renal/urinary_system_phenotyp1.51523122
34MP0003075_altered_response_to1.51178927
35MP0006082_CNS_inflammation1.50988112
36MP0009053_abnormal_anal_canal1.50720488
37MP0001849_ear_inflammation1.49988647
38MP0001299_abnormal_eye_distance/1.47842018
39MP0005508_abnormal_skeleton_morphology1.47710309
40MP0003045_fibrosis1.47464723
41MP0000534_abnormal_ureter_morphology1.46009035
42MP0010368_abnormal_lymphatic_system1.44747094
43MP0002896_abnormal_bone_mineralization1.43196366
44MP0005164_abnormal_response_to1.40972296
45MP0005365_abnormal_bile_salt1.40862781
46MP0002877_abnormal_melanocyte_morpholog1.40282296
47MP0000767_abnormal_smooth_muscle1.39933198
48MP0003950_abnormal_plasma_membrane1.39136947
49MP0000428_abnormal_craniofacial_morphol1.36292221
50MP0010234_abnormal_vibrissa_follicle1.35760140
51MP0002168_other_aberrant_phenotype1.35435015
52MP0003436_decreased_susceptibility_to1.32644188
53MP0005595_abnormal_vascular_smooth1.32177750
54MP0001542_abnormal_bone_strength1.31882766
55MP0003115_abnormal_respiratory_system1.31402245
56MP0010030_abnormal_orbit_morphology1.26668926
57MP0003942_abnormal_urinary_system1.22651995
58MP0006054_spinal_hemorrhage1.22346906
59MP0004185_abnormal_adipocyte_glucose1.22229798
60MP0003385_abnormal_body_wall1.21463821
61MP0008004_abnormal_stomach_pH1.19761532
62MP0004510_myositis1.18581463
63MP0000920_abnormal_myelination1.12697770
64MP0005167_abnormal_blood-brain_barrier1.12642318
65MP0003828_pulmonary_edema1.12445340
66MP0005409_darkened_coat_color1.11897743
67MP0001879_abnormal_lymphatic_vessel1.11634721
68MP0002998_abnormal_bone_remodeling1.10726383
69MP0000858_altered_metastatic_potential1.10229926
70MP0002419_abnormal_innate_immunity1.09990863
71MP0001915_intracranial_hemorrhage1.09420543
72MP0002295_abnormal_pulmonary_circulatio1.08890184
73MP0002060_abnormal_skin_morphology1.07969184
74MP0005165_increased_susceptibility_to1.07274956
75MP0002148_abnormal_hypersensitivity_rea1.04904667
76MP0004883_abnormal_blood_vessel1.04173725
77MP0003453_abnormal_keratinocyte_physiol1.03743090
78MP0005464_abnormal_platelet_physiology1.03595789
79MP0002933_joint_inflammation1.02724097
80MP0001853_heart_inflammation1.02621769
81MP0003935_abnormal_craniofacial_develop1.02535953
82MP0002925_abnormal_cardiovascular_devel1.02075088
83MP0004858_abnormal_nervous_system1.01946474
84MP0002282_abnormal_trachea_morphology1.00772422
85MP0000432_abnormal_head_morphology0.99155583
86MP0003634_abnormal_glial_cell0.97941080
87MP0010678_abnormal_skin_adnexa0.97759092
88MP0002092_abnormal_eye_morphology0.97013594
89MP0002108_abnormal_muscle_morphology0.96670202
90MP0003252_abnormal_bile_duct0.95478900
91MP0002697_abnormal_eye_size0.94823827
92* MP0002115_abnormal_skeleton_extremities0.94753487
93MP0000003_abnormal_adipose_tissue0.93743759
94MP0005360_urolithiasis0.93372553
95MP0000249_abnormal_blood_vessel0.93006820
96MP0009250_abnormal_appendicular_skeleto0.92880420
97MP0003937_abnormal_limbs/digits/tail_de0.91392745
98MP0003690_abnormal_glial_cell0.90792212
99MP0001614_abnormal_blood_vessel0.89375229
100MP0002135_abnormal_kidney_morphology0.88981264
101MP0002254_reproductive_system_inflammat0.88946616
102MP0004134_abnormal_chest_morphology0.88864043
103* MP0000163_abnormal_cartilage_morphology0.88860735
104MP0004197_abnormal_fetal_growth/weight/0.88285554
105MP0000751_myopathy0.88277915
106MP0005197_abnormal_uvea_morphology0.87862660
107MP0005390_skeleton_phenotype0.87682297
108MP0002128_abnormal_blood_circulation0.87604867
109MP0003448_altered_tumor_morphology0.86772072
110MP0009840_abnormal_foam_cell0.85373112
111MP0005166_decreased_susceptibility_to0.84705425
112MP0001243_abnormal_dermal_layer0.83611476
113* MP0002113_abnormal_skeleton_development0.81392103
114MP0000371_diluted_coat_color0.81365635
115MP0002932_abnormal_joint_morphology0.80238926
116MP0003724_increased_susceptibility_to0.80120050
117MP0004233_abnormal_muscle_weight0.79852062
118MP0005670_abnormal_white_adipose0.79410341
119MP0003183_abnormal_peptide_metabolism0.78329655
120MP0009780_abnormal_chondrocyte_physiolo0.76980484
121* MP0001175_abnormal_lung_morphology0.76265079
122MP0002971_abnormal_brown_adipose0.76036555
123MP0002086_abnormal_extraembryonic_tissu0.75830858
124MP0003755_abnormal_palate_morphology0.75684300
125MP0010329_abnormal_lipoprotein_level0.75600795
126MP0008260_abnormal_autophagy0.75558531
127MP0002928_abnormal_bile_duct0.74465211
128MP0002111_abnormal_tail_morphology0.73841259
129MP0009764_decreased_sensitivity_to0.73537344
130MP0000383_abnormal_hair_follicle0.73455663
131MP0004947_skin_inflammation0.72662227
132MP0002084_abnormal_developmental_patter0.72566345
133MP0002109_abnormal_limb_morphology0.72232382
134MP0001293_anophthalmia0.71554241
135MP0003195_calcinosis0.71248367
136MP0002116_abnormal_craniofacial_bone0.69458246
137MP0009785_altered_susceptibility_to0.69350223
138MP0005375_adipose_tissue_phenotype0.69270119
139MP0001533_abnormal_skeleton_physiology0.69153529
140MP0002136_abnormal_kidney_physiology0.68599173
141MP0000685_abnormal_immune_system0.68532462
142MP0005397_hematopoietic_system_phenotyp0.68453181
143MP0001545_abnormal_hematopoietic_system0.68453181
144MP0005171_absent_coat_pigmentation0.68084349
145* MP0003795_abnormal_bone_structure0.67910598
146MP0002089_abnormal_postnatal_growth/wei0.67859409
147MP0005193_abnormal_anterior_eye0.67850604
148MP0001790_abnormal_immune_system0.65461003
149MP0005387_immune_system_phenotype0.65461003
150MP0000013_abnormal_adipose_tissue0.64991808

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of liposaccharide metabolism (HP:0010968)4.85304359
2Abnormality of glycosphingolipid metabolism (HP:0004343)4.85304359
3Abnormality of glycolipid metabolism (HP:0010969)4.85304359
4Protrusio acetabuli (HP:0003179)4.11945315
5Cerebral aneurysm (HP:0004944)4.06703336
6Systemic lupus erythematosus (HP:0002725)4.02211166
7Premature rupture of membranes (HP:0001788)3.83112220
8Shallow orbits (HP:0000586)3.79434923
9Ankle contracture (HP:0006466)3.58076898
10Complement deficiency (HP:0004431)3.27462475
11Myocardial infarction (HP:0001658)3.14184298
12Aortic aneurysm (HP:0004942)3.08931131
13Focal segmental glomerulosclerosis (HP:0000097)3.06250707
14Abnormality of complement system (HP:0005339)3.03630252
15Vacuolated lymphocytes (HP:0001922)2.97341612
16Atrophic scars (HP:0001075)2.93854362
17Aortic dissection (HP:0002647)2.91211359
18Neurofibrillary tangles (HP:0002185)2.90003316
19Broad metatarsal (HP:0001783)2.89657507
20Hematochezia (HP:0002573)2.73908906
21Ulnar bowing (HP:0003031)2.69426913
22Mitral valve prolapse (HP:0001634)2.69047311
23Short 4th metacarpal (HP:0010044)2.66158490
24Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.66158490
25Increased cerebral lipofuscin (HP:0011813)2.63837772
26Mitral stenosis (HP:0001718)2.63568417
27Cervical subluxation (HP:0003308)2.63484914
28Nuclear cataract (HP:0100018)2.54074824
29Turricephaly (HP:0000262)2.53344216
30Bladder diverticulum (HP:0000015)2.53337593
31Loss of speech (HP:0002371)2.47422944
32Lymphangioma (HP:0100764)2.44143749
33Aneurysm (HP:0002617)2.38795012
34Dilatation of the ascending aorta (HP:0005111)2.37300682
35Xanthomatosis (HP:0000991)2.34941921
36Genu recurvatum (HP:0002816)2.33116026
37Cerebral inclusion bodies (HP:0100314)2.32123893
38Glomerulosclerosis (HP:0000096)2.30528891
39Blue sclerae (HP:0000592)2.28794122
40Mesangial abnormality (HP:0001966)2.28182924
41Peritonitis (HP:0002586)2.24148171
42Interstitial pulmonary disease (HP:0006530)2.22264759
43Asymmetric septal hypertrophy (HP:0001670)2.21758390
44Ovoid vertebral bodies (HP:0003300)2.21433326
45Neonatal short-limb short stature (HP:0008921)2.19742794
46Osteolytic defects of the hand bones (HP:0009699)2.18842342
47Osteolytic defects of the phalanges of the hand (HP:0009771)2.18842342
48Vascular tortuosity (HP:0004948)2.18462147
49Skin nodule (HP:0200036)2.17088563
50Arterial tortuosity (HP:0005116)2.15346397
51Dysostosis multiplex (HP:0000943)2.13964523
52Abnormality of the 4th metacarpal (HP:0010012)2.13807271
53Joint stiffness (HP:0001387)2.11107168
54Urethral obstruction (HP:0000796)2.10348511
55Distal upper limb amyotrophy (HP:0007149)2.09988149
56Upper limb amyotrophy (HP:0009129)2.09988149
57Mucopolysacchariduria (HP:0008155)2.07673474
58Urinary glycosaminoglycan excretion (HP:0003541)2.07673474
59Nephritis (HP:0000123)2.06211476
60Short nail (HP:0001799)2.04415038
61Deep venous thrombosis (HP:0002625)2.02645582
62Spinal rigidity (HP:0003306)2.02638097
63Camptodactyly of toe (HP:0001836)2.00545408
64Fragile skin (HP:0001030)1.99993844
65Scapular winging (HP:0003691)1.98464615
66Hand muscle atrophy (HP:0009130)1.97734879
67Abnormality of polysaccharide metabolism (HP:0011012)1.97373882
68Abnormality of glycosaminoglycan metabolism (HP:0004371)1.97373882
69Abnormality of mucopolysaccharide metabolism (HP:0011020)1.97373882
70Protuberant abdomen (HP:0001538)1.95854479
71Disproportionate tall stature (HP:0001519)1.95632660
72Abnormality of the peritoneum (HP:0002585)1.94525705
73Abnormality of macrophages (HP:0004311)1.93682155
74Coronal craniosynostosis (HP:0004440)1.92199525
75Deviation of the hallux (HP:0010051)1.91832898
76Amyloidosis (HP:0011034)1.91390072
77Striae distensae (HP:0001065)1.91307511
78Mitral regurgitation (HP:0001653)1.91033583
79Soft skin (HP:0000977)1.90568906
80Increased neuronal autofluorescent lipopigment (HP:0002074)1.90133273
81Hypoplastic ischia (HP:0003175)1.89209583
82Bone pain (HP:0002653)1.87878961
83Spondylolisthesis (HP:0003302)1.85569811
84Bowed forearm bones (HP:0003956)1.85359678
85Bowing of the arm (HP:0006488)1.85359678
86Purpura (HP:0000979)1.85023236
87Metaphyseal cupping (HP:0003021)1.84936534
88Long toe (HP:0010511)1.84850922
89Hallux valgus (HP:0001822)1.84840016
90Natal tooth (HP:0000695)1.84775270
91Broad thumb (HP:0011304)1.84349036
92Bowel diverticulosis (HP:0005222)1.84114987
93Vertebral compression fractures (HP:0002953)1.82718330
94Broad face (HP:0000283)1.82686158
95Thin bony cortex (HP:0002753)1.81499582
96Renal duplication (HP:0000075)1.81424954
97Wormian bones (HP:0002645)1.80714480
98Persistence of primary teeth (HP:0006335)1.78594266
99Bell-shaped thorax (HP:0001591)1.78506839
100Abnormality of dentin (HP:0010299)1.78055309
101J-shaped sella turcica (HP:0002680)1.77829139
102Cupped ribs (HP:0000887)1.77192145
103Macroorchidism (HP:0000053)1.75698145
104Narrow palate (HP:0000189)1.75014768
105Flared iliac wings (HP:0002869)1.74882193
106Flat acetabular roof (HP:0003180)1.73762876
107Biconcave vertebral bodies (HP:0004586)1.73737429
108Glomerulonephritis (HP:0000099)1.73235519
109Exostoses (HP:0100777)1.73178010
110Distal lower limb muscle weakness (HP:0009053)1.72385514
111Distal lower limb amyotrophy (HP:0008944)1.71184291
112Aortic regurgitation (HP:0001659)1.70980792
113Cardiovascular calcification (HP:0011915)1.70683104
114Hyperextensible skin (HP:0000974)1.70167853
115Hyperacusis (HP:0010780)1.70129196
116Esophageal varix (HP:0002040)1.69362848
117Buphthalmos (HP:0000557)1.68309969
118Malnutrition (HP:0004395)1.68303520
119Achilles tendon contracture (HP:0001771)1.68131063
120Abnormality of the ischium (HP:0003174)1.67996086
121Hypoalbuminemia (HP:0003073)1.67209920
122Abnormal albumin level (HP:0012116)1.67209920
123Abnormality of the distal phalanx of the thumb (HP:0009617)1.66505422
124Increased CSF protein (HP:0002922)1.66221601
125Hypoalphalipoproteinemia (HP:0003233)1.66069851
126Abnormality of carpal bone ossification (HP:0006257)1.65836266
127Apathy (HP:0000741)1.65813365
128Coxa vara (HP:0002812)1.65549019
129Abnormal ossification of hand bones (HP:0005921)1.64944847
130Abnormality of the Achilles tendon (HP:0005109)1.64448745
131Increased connective tissue (HP:0009025)1.64288461
132Milia (HP:0001056)1.63626417
133Protruding ear (HP:0000411)1.63588621
134Absent frontal sinuses (HP:0002688)1.63053106
135Joint laxity (HP:0001388)1.62425503
136Rectal prolapse (HP:0002035)1.61817027
137Broad ribs (HP:0000885)1.61351491
138Axonal loss (HP:0003447)1.60755272
139Abnormality of the acetabulum (HP:0003170)1.60657219
140Broad long bones (HP:0005622)1.60318537
141Femoral bowing (HP:0002980)1.58328050
142Arnold-Chiari malformation (HP:0002308)1.58153703
143Radial bowing (HP:0002986)1.56645652
144Tibial bowing (HP:0002982)1.56290619
145Subacute progressive viral hepatitis (HP:0006572)1.55688004
146Wide anterior fontanel (HP:0000260)1.53963758
147Increased density of long bones (HP:0006392)1.51761201
148Pathologic fracture (HP:0002756)1.51731688
149Spinal cord lesions (HP:0100561)1.51396756

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.38659432
2TRIB33.26460371
3LATS13.18846670
4PDGFRA2.88093331
5CDK122.86615872
6TTN2.61812801
7TGFBR22.61380205
8DDR22.53618620
9PTK62.47599435
10RIPK12.43371743
11PKN22.37532148
12SIK12.36919720
13ERN12.36198618
14PAK42.17726625
15CAMK1D2.09596269
16EPHB11.99132274
17MYLK1.96861259
18EPHA21.91634016
19MST1R1.89836389
20CAMK1G1.77957129
21PTK21.77263787
22PRPF4B1.74807099
23PDGFRB1.71518375
24EPHB21.67533909
25BMX1.63083044
26ICK1.61996014
27PAK21.57010787
28NME21.54019340
29STK31.53801373
30MTOR1.48109250
31TESK11.43610265
32TYRO31.40471185
33MET1.39680685
34MAPK151.32796287
35ABL21.30857821
36LIMK11.30226321
37SCYL21.23928301
38BLK1.21532094
39MAP3K21.21249820
40GRK71.19775005
41NTRK11.19003116
42LRRK21.17117306
43WNK41.13923584
44DMPK1.10698047
45CDK61.10382214
46MAP3K101.07486566
47KIT1.06952515
48MAP3K141.06649252
49LATS21.06043281
50JAK11.04850867
51EEF2K1.04792153
52FER1.02931856
53EPHA30.97467687
54FGFR20.97356201
55ZAP700.95763051
56RPS6KA20.95758918
57PDPK10.94282412
58CSK0.94254360
59STK100.91559450
60FGFR40.90392683
61NEK90.90147571
62WNK10.89606414
63TAOK20.88983473
64RET0.87224045
65MAP3K130.87067665
66BRD40.86475023
67PRKD20.86021587
68CSF1R0.84003511
69AKT30.83719059
70GSK3A0.81021914
71ERBB20.80814801
72SMG10.79697626
73ALK0.74131828
74CHUK0.73132372
75TYK20.72213168
76FGFR10.71745706
77MAP3K10.69728607
78MAPK70.66887531
79PDK20.66267507
80TBK10.66023303
81EGFR0.65669319
82INSR0.63918358
83ROCK10.62357573
84MARK20.61542284
85JAK30.61134503
86KSR20.60521976
87PIM20.58269280
88FRK0.58260461
89TAOK30.57942622
90TGFBR10.56903967
91MAP3K60.56798710
92FGFR30.55049494
93TRPM70.53866172
94PAK30.53241953
95PRKD10.53221141
96MAPK110.52452921
97STK390.52260183
98MAP3K30.51674890
99PRKCH0.51589555
100MAP3K80.50635128
101RPS6KC10.50133500
102RPS6KL10.50133500
103RPS6KA40.49710733
104PIK3CG0.49239903
105* SRC0.48795310
106JAK20.48565789
107CAMK2G0.48270970
108FGR0.47828278
109PRKD30.47648096
110ROCK20.47000246
111MAP2K30.46628963
112SGK30.46600889
113PRKAA20.46600740
114DYRK1B0.45923567
115PTK2B0.43154807
116ABL10.42181117
117MAPKAPK30.41454203
118CAMKK10.40838372
119PDK10.40791613
120FYN0.40674666
121CDC42BPA0.40582883
122PRKG20.39453364
123MAPK120.38964439
124HCK0.38725926
125MAPK10.37902748
126MAP3K70.36644560
127MATK0.36121705
128FLT30.34028602
129IGF1R0.33307625
130PAK60.33169618
131SIK20.33117052
132FES0.31629254
133MELK0.30114922
134LMTK20.29930684
135ERBB40.29727343
136STK380.29480369
137MOS0.29344490

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.73488191
2Focal adhesion_Homo sapiens_hsa045102.25211798
3Glycosaminoglycan degradation_Homo sapiens_hsa005312.12326661
4Small cell lung cancer_Homo sapiens_hsa052221.92318320
5Adherens junction_Homo sapiens_hsa045201.92259047
6Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.90677213
7Lysosome_Homo sapiens_hsa041421.86877689
8Proteoglycans in cancer_Homo sapiens_hsa052051.84984181
9Amoebiasis_Homo sapiens_hsa051461.83420970
10Nitrogen metabolism_Homo sapiens_hsa009101.74049045
11Chronic myeloid leukemia_Homo sapiens_hsa052201.64786854
12AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.64399113
13Protein digestion and absorption_Homo sapiens_hsa049741.55146612
14MicroRNAs in cancer_Homo sapiens_hsa052061.49857029
15PPAR signaling pathway_Homo sapiens_hsa033201.48932821
16Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.39399358
17Bladder cancer_Homo sapiens_hsa052191.31076258
18Regulation of actin cytoskeleton_Homo sapiens_hsa048101.30904368
19Hippo signaling pathway_Homo sapiens_hsa043901.29905659
20Leukocyte transendothelial migration_Homo sapiens_hsa046701.29189364
21Lysine degradation_Homo sapiens_hsa003101.28539063
22Pancreatic cancer_Homo sapiens_hsa052121.28045198
23mTOR signaling pathway_Homo sapiens_hsa041501.25775155
24Galactose metabolism_Homo sapiens_hsa000521.25725285
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22392169
26Basal cell carcinoma_Homo sapiens_hsa052171.22175927
27Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.19950974
28Osteoclast differentiation_Homo sapiens_hsa043801.19550471
29Renal cell carcinoma_Homo sapiens_hsa052111.15935989
30Rheumatoid arthritis_Homo sapiens_hsa053231.15053995
31Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14746849
32Prostate cancer_Homo sapiens_hsa052151.14187351
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.13980401
34Glioma_Homo sapiens_hsa052141.13181815
35Type II diabetes mellitus_Homo sapiens_hsa049301.12094270
36TGF-beta signaling pathway_Homo sapiens_hsa043501.12033290
37Vibrio cholerae infection_Homo sapiens_hsa051101.11980142
38Toxoplasmosis_Homo sapiens_hsa051451.11857352
39Notch signaling pathway_Homo sapiens_hsa043301.10842056
40Sphingolipid metabolism_Homo sapiens_hsa006001.03821547
41Endometrial cancer_Homo sapiens_hsa052131.02690985
42PI3K-Akt signaling pathway_Homo sapiens_hsa041511.02345370
43Other glycan degradation_Homo sapiens_hsa005111.02005456
44Renin-angiotensin system_Homo sapiens_hsa046141.01337745
45Dorso-ventral axis formation_Homo sapiens_hsa043201.00162445
46Melanoma_Homo sapiens_hsa052180.99008103
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98076639
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97703565
49Platelet activation_Homo sapiens_hsa046110.94971088
50Hedgehog signaling pathway_Homo sapiens_hsa043400.93988667
51Insulin resistance_Homo sapiens_hsa049310.93727260
52Pathways in cancer_Homo sapiens_hsa052000.90792918
53Colorectal cancer_Homo sapiens_hsa052100.89630275
54Rap1 signaling pathway_Homo sapiens_hsa040150.89437092
55Leishmaniasis_Homo sapiens_hsa051400.89368607
56Neurotrophin signaling pathway_Homo sapiens_hsa047220.88693624
57Carbohydrate digestion and absorption_Homo sapiens_hsa049730.87807353
58TNF signaling pathway_Homo sapiens_hsa046680.86777267
59Axon guidance_Homo sapiens_hsa043600.86775650
60Dilated cardiomyopathy_Homo sapiens_hsa054140.85964162
61Toll-like receptor signaling pathway_Homo sapiens_hsa046200.85066909
62Malaria_Homo sapiens_hsa051440.83731840
63Viral myocarditis_Homo sapiens_hsa054160.82778999
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82011495
65Fructose and mannose metabolism_Homo sapiens_hsa000510.81831704
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81492443
67Estrogen signaling pathway_Homo sapiens_hsa049150.80415472
68Tight junction_Homo sapiens_hsa045300.80088762
69Shigellosis_Homo sapiens_hsa051310.79385605
70Endocytosis_Homo sapiens_hsa041440.79288265
71Sulfur metabolism_Homo sapiens_hsa009200.78441239
72Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.78282947
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.78175359
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77898041
75Central carbon metabolism in cancer_Homo sapiens_hsa052300.77590490
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76826083
77Apoptosis_Homo sapiens_hsa042100.75814756
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75486080
79Non-small cell lung cancer_Homo sapiens_hsa052230.75100507
80Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.74740978
81Pentose phosphate pathway_Homo sapiens_hsa000300.73727249
82Staphylococcus aureus infection_Homo sapiens_hsa051500.73467450
83Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.72876946
84Tuberculosis_Homo sapiens_hsa051520.72684166
85Phagosome_Homo sapiens_hsa041450.72234389
86VEGF signaling pathway_Homo sapiens_hsa043700.72035500
87Caffeine metabolism_Homo sapiens_hsa002320.70611035
88Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70346029
89B cell receptor signaling pathway_Homo sapiens_hsa046620.69934340
90Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68600784
91Vitamin B6 metabolism_Homo sapiens_hsa007500.68529983
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.68165651
93Pertussis_Homo sapiens_hsa051330.67630849
94Histidine metabolism_Homo sapiens_hsa003400.66180319
95Acute myeloid leukemia_Homo sapiens_hsa052210.65161534
96Salmonella infection_Homo sapiens_hsa051320.64371547
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62664582
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61267329
99Prion diseases_Homo sapiens_hsa050200.61018216
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.60457420
101Hepatitis B_Homo sapiens_hsa051610.60347861
102Complement and coagulation cascades_Homo sapiens_hsa046100.59685257
103Mineral absorption_Homo sapiens_hsa049780.59228984
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.59081512
105GnRH signaling pathway_Homo sapiens_hsa049120.59063526
106Choline metabolism in cancer_Homo sapiens_hsa052310.58795018
107Adipocytokine signaling pathway_Homo sapiens_hsa049200.58133859
108Prolactin signaling pathway_Homo sapiens_hsa049170.57806717
109Viral carcinogenesis_Homo sapiens_hsa052030.55635653
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54906257
111Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.54773490
112Bile secretion_Homo sapiens_hsa049760.54612759
113Influenza A_Homo sapiens_hsa051640.54373285
114Hepatitis C_Homo sapiens_hsa051600.53391398
115HTLV-I infection_Homo sapiens_hsa051660.52472441
116Wnt signaling pathway_Homo sapiens_hsa043100.51992163
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.51880432
118Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45325890
119Insulin signaling pathway_Homo sapiens_hsa049100.44735904
120Cyanoamino acid metabolism_Homo sapiens_hsa004600.44673527
121Chemokine signaling pathway_Homo sapiens_hsa040620.44123920
122African trypanosomiasis_Homo sapiens_hsa051430.43907414
123Legionellosis_Homo sapiens_hsa051340.43836300
124HIF-1 signaling pathway_Homo sapiens_hsa040660.41980730
125Fatty acid biosynthesis_Homo sapiens_hsa000610.41663802
126Thyroid hormone synthesis_Homo sapiens_hsa049180.40094340
127Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.38879495
128N-Glycan biosynthesis_Homo sapiens_hsa005100.37911684
129Starch and sucrose metabolism_Homo sapiens_hsa005000.36075281

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »