TNS4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of skin barrier (GO:0061436)8.12067885
2keratinization (GO:0031424)7.98107412
3regulation of water loss via skin (GO:0033561)7.86394027
4bundle of His cell to Purkinje myocyte communication (GO:0086069)7.27505362
5molting cycle (GO:0042303)6.55685246
6hair cycle (GO:0042633)6.55685246
7keratinocyte proliferation (GO:0043616)5.93924585
8keratinocyte differentiation (GO:0030216)5.82019522
9keratinocyte development (GO:0003334)5.45026878
10negative regulation of keratinocyte proliferation (GO:0010839)5.43906123
11multicellular organismal water homeostasis (GO:0050891)5.31605090
12interferon-gamma secretion (GO:0072643)5.11793234
13intermediate filament organization (GO:0045109)5.06585758
14peptide cross-linking (GO:0018149)4.84171740
15intestinal epithelial cell development (GO:0060576)4.80667631
16surfactant homeostasis (GO:0043129)4.73975470
17regulation of chemokine secretion (GO:0090196)4.62477211
18polarized epithelial cell differentiation (GO:0030859)4.59106540
19epidermis development (GO:0008544)4.44638616
20dichotomous subdivision of an epithelial terminal unit (GO:0060600)4.44593494
21epidermal cell differentiation (GO:0009913)4.43376350
22cell-substrate junction assembly (GO:0007044)4.38816086
23water homeostasis (GO:0030104)4.38588000
24gap junction assembly (GO:0016264)4.13951912
25lateral sprouting from an epithelium (GO:0060601)4.09378739
26epithelial cell differentiation involved in prostate gland development (GO:0060742)4.04833696
27regulation of transforming growth factor beta2 production (GO:0032909)4.03584653
28positive regulation of hair follicle development (GO:0051798)3.98953272
29positive regulation of hair cycle (GO:0042635)3.98953272
30mesodermal cell differentiation (GO:0048333)3.92223150
31activation of Rac GTPase activity (GO:0032863)3.90691401
32negative regulation of cell fate specification (GO:0009996)3.88000167
33regulation of keratinocyte proliferation (GO:0010837)3.87924427
34chemical homeostasis within a tissue (GO:0048875)3.86039239
35positive regulation of keratinocyte differentiation (GO:0045618)3.82241680
36hypotonic response (GO:0006971)3.79822351
37morphogenesis of embryonic epithelium (GO:0016331)3.79236669
38skin morphogenesis (GO:0043589)3.75847230
39positive regulation of interleukin-8 secretion (GO:2000484)3.74028583
40negative regulation of chondrocyte differentiation (GO:0032331)3.65872077
41negative regulation of cell fate commitment (GO:0010454)3.54414182
42cytoskeletal anchoring at plasma membrane (GO:0007016)3.52464578
43regulation of interleukin-8 secretion (GO:2000482)3.49852873
44plasma membrane repair (GO:0001778)3.49199848
45ectoderm development (GO:0007398)3.48590258
46cell junction assembly (GO:0034329)3.40463860
47mammary gland epithelial cell proliferation (GO:0033598)3.34636082
48cell junction organization (GO:0034330)3.33450258
49protein localization to endosome (GO:0036010)3.32658218
50intermediate filament cytoskeleton organization (GO:0045104)3.30656210
51hepatocyte apoptotic process (GO:0097284)3.21286130
52atrioventricular valve morphogenesis (GO:0003181)3.20535548
53intermediate filament-based process (GO:0045103)3.18678153
54sphingoid metabolic process (GO:0046519)3.18624364
55L-serine transport (GO:0015825)3.18278242
56regulation of epidermal growth factor-activated receptor activity (GO:0007176)3.17513546
57regulation of keratinocyte differentiation (GO:0045616)3.16784435
58detection of bacterium (GO:0016045)3.15027718
59cell-substrate adherens junction assembly (GO:0007045)3.14713157
60focal adhesion assembly (GO:0048041)3.14713157
61regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.11252759
62detection of other organism (GO:0098543)3.10395013
63regulation of ruffle assembly (GO:1900027)3.07856263
64positive regulation of epidermis development (GO:0045684)3.07745011
65positive regulation of epidermal cell differentiation (GO:0045606)3.05764442
66diol metabolic process (GO:0034311)3.05133035
67branching involved in mammary gland duct morphogenesis (GO:0060444)3.01593803
68sphingosine metabolic process (GO:0006670)3.01280391
69regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.97226994
70virion attachment to host cell (GO:0019062)2.96801651
71adhesion of symbiont to host cell (GO:0044650)2.96801651
72endodermal cell differentiation (GO:0035987)2.94889228
73maintenance of gastrointestinal epithelium (GO:0030277)2.90208600
74epithelial cell-cell adhesion (GO:0090136)2.86900694
75regulation of epidermis development (GO:0045682)2.86149865
76skin development (GO:0043588)2.84827118
77renal system development (GO:0072001)2.82400768
78negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.80475037
79renal filtration (GO:0097205)2.80110405
80semaphorin-plexin signaling pathway (GO:0071526)2.79999069
81adherens junction organization (GO:0034332)2.78357628
82ventricular cardiac muscle cell action potential (GO:0086005)2.75900448
83adherens junction assembly (GO:0034333)2.75630258
84protein localization to microtubule (GO:0035372)2.73282195
85regulation of endothelial cell chemotaxis (GO:2001026)2.72980429
86lung lobe morphogenesis (GO:0060463)2.72525052
87regulation of phospholipase A2 activity (GO:0032429)2.70003893
88phosphatidylserine acyl-chain remodeling (GO:0036150)2.69029202
89mammary gland development (GO:0030879)2.66852286
90odontogenesis of dentin-containing tooth (GO:0042475)2.63743989
91hair follicle morphogenesis (GO:0031069)2.63503707
92glucosamine-containing compound catabolic process (GO:1901072)2.63177580
93regulation of epidermal cell differentiation (GO:0045604)2.63136216
94filopodium assembly (GO:0046847)2.62932099
95endosome organization (GO:0007032)2.60994454
96serine transport (GO:0032329)2.60334795
97negative regulation of cartilage development (GO:0061037)2.60008357
98negative regulation of stem cell proliferation (GO:2000647)2.59488959
99regulation of hair follicle development (GO:0051797)2.59158793
100phosphatidylinositol acyl-chain remodeling (GO:0036149)2.59131218
101negative regulation of anoikis (GO:2000811)2.58141387
102regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.57400392
103odontogenesis (GO:0042476)2.57298096
104wound healing, spreading of epidermal cells (GO:0035313)2.55993117
105cell communication involved in cardiac conduction (GO:0086065)2.55243444
106regulation of anoikis (GO:2000209)2.53862455
107wound healing (GO:0042060)2.53227597
108positive regulation of odontogenesis (GO:0042482)2.52934427
109positive regulation of chemokine secretion (GO:0090197)2.51932546
110positive regulation of monocyte chemotaxis (GO:0090026)2.51713705
111membrane raft organization (GO:0031579)2.51343998
112regulation of cardioblast differentiation (GO:0051890)2.51147204
113regulation of metalloenzyme activity (GO:0048552)2.50745133
114eyelid development in camera-type eye (GO:0061029)2.50000117
115epithelial structure maintenance (GO:0010669)2.47548502
116positive regulation of actin filament depolymerization (GO:0030836)2.46592601
117cell differentiation involved in embryonic placenta development (GO:0060706)2.44319708
118regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.43658739
119establishment of tissue polarity (GO:0007164)2.41754451
120establishment of planar polarity (GO:0001736)2.41754451
121regulation of hair cycle (GO:0042634)2.40599634
122intestinal absorption (GO:0050892)2.40415810
123cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.39854142
124cell adhesion mediated by integrin (GO:0033627)2.38832265
125negative regulation of epidermis development (GO:0045683)2.38711885
126regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.37446681
127regulation of apoptotic process involved in morphogenesis (GO:1902337)2.37272461
128epithelium development (GO:0060429)2.36026475
129regulation of cell fate specification (GO:0042659)2.34889632
130ear development (GO:0043583)2.34074275
131regulation of cell proliferation involved in kidney development (GO:1901722)2.33952703
132tumor necrosis factor-mediated signaling pathway (GO:0033209)2.33516835
133cardiac right ventricle morphogenesis (GO:0003215)2.32664488
134molting cycle process (GO:0022404)2.29133388
135hair cycle process (GO:0022405)2.29133388
136adhesion of symbiont to host (GO:0044406)2.28959466
137regulation of podosome assembly (GO:0071801)2.27600344
138planar cell polarity pathway involved in neural tube closure (GO:0090179)2.27549261
139regulation of heart rate by cardiac conduction (GO:0086091)2.27255759
140branching involved in labyrinthine layer morphogenesis (GO:0060670)2.26801868
141gland morphogenesis (GO:0022612)2.25862354
142neural crest cell development (GO:0014032)2.23413261
143negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.22969503
144regulation of glomerular filtration (GO:0003093)2.22857215
145lipoxygenase pathway (GO:0019372)2.21264264
146hemidesmosome assembly (GO:0031581)13.8133544
147desmosome organization (GO:0002934)11.8733575

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.98017369
2SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.34548022
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.87907613
4* SOX9_24532713_ChIP-Seq_HFSC_Mouse2.70118605
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.50695503
6P63_26484246_Chip-Seq_KERATINOCYTES_Human2.42747221
7CDX2_20551321_ChIP-Seq_CACO-2_Human2.22616746
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.19797139
9SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.19227353
10SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.19227353
11TP63_17297297_ChIP-ChIP_HaCaT_Human15.0629279
12* SOX2_20726797_ChIP-Seq_SW620_Human1.88869991
13STAT6_21828071_ChIP-Seq_BEAS2B_Human1.88027441
14ESR2_21235772_ChIP-Seq_MCF-7_Human1.84209722
15FOXO3_23340844_ChIP-Seq_DLD1_Human1.82265022
16ZNF217_24962896_ChIP-Seq_MCF-7_Human1.77632267
17CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.74870115
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.70970761
19TCF4_18268006_ChIP-ChIP_LS174T_Human1.63927828
20GATA4_25053715_ChIP-Seq_YYC3_Human1.62214977
21KLF5_25053715_ChIP-Seq_YYC3_Human1.60739575
22ELK3_25401928_ChIP-Seq_HUVEC_Human1.52991339
23* CJUN_26792858_Chip-Seq_BT549_Human1.49678506
24FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.49360526
25* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.49175836
26STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.47399795
27ZNF263_19887448_ChIP-Seq_K562_Human1.45687867
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.43777120
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.43420455
30GATA6_25053715_ChIP-Seq_YYC3_Human1.41348609
31RARG_19884340_ChIP-ChIP_MEFs_Mouse1.38975803
32P300_27058665_Chip-Seq_ZR-75-30cells_Human1.33309673
33RUNX1_27514584_Chip-Seq_MCF-7_Human1.32766672
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31364146
35FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.31215960
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.29794737
37HIF1A_21447827_ChIP-Seq_MCF-7_Human1.28404905
38CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27054482
39PPAR_26484153_Chip-Seq_NCI-H1993_Human1.26113097
40PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.25452719
41KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24173521
42TP53_18474530_ChIP-ChIP_U2OS_Human1.21590936
43PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.21298152
44RACK7_27058665_Chip-Seq_MCF-7_Human1.20368982
45FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.19499767
46CLOCK_20551151_ChIP-Seq_293T_Human1.18983638
47TP63_23658742_ChIP-Seq_EP156T_Human1.18228470
48AHR_22903824_ChIP-Seq_MCF-7_Human1.16362582
49RXR_22108803_ChIP-Seq_LS180_Human1.15056557
50JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13656723
51LXR_22292898_ChIP-Seq_THP-1_Human1.10769209
52NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.09578121
53NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.09322637
54* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.09288024
55KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.08840707
56GATA3_24758297_ChIP-Seq_MCF-7_Human1.04878702
57* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03619702
58GATA2_21666600_ChIP-Seq_HMVEC_Human1.03272296
59JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02465218
60CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.02370719
61TP53_22127205_ChIP-Seq_IMR90_Human1.00809221
62AR_21909140_ChIP-Seq_LNCAP_Human1.00576497
63RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.00241135
64AR_21572438_ChIP-Seq_LNCaP_Human0.96679509
65HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.96503013
66PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.95585391
67ATF3_27146783_Chip-Seq_COLON_Human0.94182953
68Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.92568787
69TP63_22573176_ChIP-Seq_HFKS_Human0.92252344
70BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.91180471
71TP53_16413492_ChIP-PET_HCT116_Human0.90685089
72EGR1_19032775_ChIP-ChIP_M12_Human0.88616877
73SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.88466793
74* UBF1/2_26484160_Chip-Seq_HMECs_Human0.86805982
75* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.86319101
76* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.86059090
77KDM2B_26808549_Chip-Seq_K562_Human0.85450278
78STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.85446361
79FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85261924
80ARNT_22903824_ChIP-Seq_MCF-7_Human0.83601279
81* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83233112
82* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.82954872
83BMI1_23680149_ChIP-Seq_NPCS_Mouse0.82743915
84BCAT_22108803_ChIP-Seq_LS180_Human0.82346517
85IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.82236437
86IRF8_22096565_ChIP-ChIP_GC-B_Human0.82200298
87KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80681361
88TET1_21490601_ChIP-Seq_MESCs_Mouse0.80254385
89* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.78818767
90TP53_20018659_ChIP-ChIP_R1E_Mouse0.78218238
91SMAD3_21741376_ChIP-Seq_HESCs_Human0.78006635
92* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77585227
93ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.77480394
94ERG_21242973_ChIP-ChIP_JURKAT_Human0.77226462
95GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.77115322
96SMC4_20622854_ChIP-Seq_HELA_Human0.75950910
97TBX20_22328084_ChIP-Seq_HEART_Mouse0.75920210
98TBX20_22080862_ChIP-Seq_HEART_Mouse0.75920210
99SRY_22984422_ChIP-ChIP_TESTIS_Rat0.75208784
100BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74857592
101SMAD_19615063_ChIP-ChIP_OVARY_Human0.74275831
102* SA1_27219007_Chip-Seq_ERYTHROID_Human0.74113843
103CTCF_27219007_Chip-Seq_Bcells_Human0.72231695
104WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.71482609
105TP53_23651856_ChIP-Seq_MEFs_Mouse0.70937511
106PPARA_22158963_ChIP-Seq_LIVER_Mouse0.70465105
107VDR_24787735_ChIP-Seq_THP-1_Human0.69541955
108NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.68371673
109CREB1_26743006_Chip-Seq_LNCaP_Human0.68280915
110CHD1_26751641_Chip-Seq_LNCaP_Human0.67774993
111KLF4_18555785_ChIP-Seq_MESCs_Mouse0.67650748
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.65034887
113GATA6_21074721_ChIP-Seq_CACO-2_Human0.64838731
114FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.63783622
115ELK1_22589737_ChIP-Seq_MCF10A_Human0.62583775
116SUZ12_27294783_Chip-Seq_ESCs_Mouse0.62406644
117CTNNB1_20460455_ChIP-Seq_HCT116_Human0.62017171
118EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.61533636
119CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.61065099
120CDX2_22108803_ChIP-Seq_LS180_Human0.60785901
121NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.60355694
122* FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.60293966
123P68_20966046_ChIP-Seq_HELA_Human0.59834020
124RXR_22158963_ChIP-Seq_LIVER_Mouse0.59589385
125ELK4_26923725_Chip-Seq_MESODERM_Mouse0.58795127
126AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.57671448
127NRF2_20460467_ChIP-Seq_MEFs_Mouse0.55519147
128NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.55519147
129PIAS1_25552417_ChIP-Seq_VCAP_Human0.55272434
130EZH2_27294783_Chip-Seq_ESCs_Mouse0.54886156
131* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.53405868
132ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.52844579
133RBPJ_21746931_ChIP-Seq_IB4_Human0.52836720
134SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.52625409
135JARID2_20075857_ChIP-Seq_MESCs_Mouse0.52592443
136CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.52204488
137EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.51540581
138GATA2_19941826_ChIP-Seq_K562_Human0.50848707
139SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.50255965
140CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.50039616
141TCF4_22108803_ChIP-Seq_LS180_Human0.50027288
142MYB_21317192_ChIP-Seq_ERMYB_Mouse0.49999537

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier5.33557279
2MP0010234_abnormal_vibrissa_follicle4.66068503
3MP0002254_reproductive_system_inflammat4.51926852
4MP0000579_abnormal_nail_morphology4.17934164
5MP0005275_abnormal_skin_tensile3.82509503
6MP0000383_abnormal_hair_follicle3.76558617
7MP0002060_abnormal_skin_morphology3.49290725
8MP0005501_abnormal_skin_physiology3.47281232
9MP0003941_abnormal_skin_development3.44198397
10MP0010678_abnormal_skin_adnexa3.34176531
11MP0001216_abnormal_epidermal_layer3.27222475
12MP0002098_abnormal_vibrissa_morphology3.10195168
13MP0003453_abnormal_keratinocyte_physiol3.05645039
14MP0003705_abnormal_hypodermis_morpholog2.98878564
15MP0000467_abnormal_esophagus_morphology2.69831963
16MP0000427_abnormal_hair_cycle2.59584840
17MP0010771_integument_phenotype2.55700202
18MP0000647_abnormal_sebaceous_gland2.55010084
19MP0004947_skin_inflammation2.41975206
20MP0000566_synostosis2.41017993
21MP0001346_abnormal_lacrimal_gland2.39047183
22MP0004381_abnormal_hair_follicle2.33396005
23MP0000762_abnormal_tongue_morphology2.30131980
24MP0000377_abnormal_hair_follicle2.28479591
25MP0003566_abnormal_cell_adhesion2.15648348
26MP0001849_ear_inflammation2.09608646
27MP0002234_abnormal_pharynx_morphology2.03813992
28MP0000537_abnormal_urethra_morphology2.00948991
29MP0004264_abnormal_extraembryonic_tissu1.85298984
30MP0010352_gastrointestinal_tract_polyps1.60952042
31MP0001191_abnormal_skin_condition1.60863954
32MP0009931_abnormal_skin_appearance1.57945606
33MP0000538_abnormal_urinary_bladder1.54710381
34MP0009780_abnormal_chondrocyte_physiolo1.50242886
35MP0000462_abnormal_digestive_system1.45974338
36MP0009379_abnormal_foot_pigmentation1.42043659
37MP0010155_abnormal_intestine_physiology1.35188031
38MP0001851_eye_inflammation1.33504685
39MP0005023_abnormal_wound_healing1.27907199
40MP0009053_abnormal_anal_canal1.24556697
41MP0001243_abnormal_dermal_layer1.16976233
42MP0000367_abnormal_coat/_hair1.16678405
43MP0005360_urolithiasis1.12229781
44MP0003866_abnormal_defecation1.08967936
45MP0000627_abnormal_mammary_gland1.08901430
46MP0002277_abnormal_respiratory_mucosa1.08684681
47MP0000516_abnormal_urinary_system1.08262528
48MP0005367_renal/urinary_system_phenotyp1.08262528
49MP0000465_gastrointestinal_hemorrhage1.06287830
50MP0008004_abnormal_stomach_pH1.04701249
51MP0008789_abnormal_olfactory_epithelium1.03141093
52MP0003950_abnormal_plasma_membrane1.02576257
53MP0002877_abnormal_melanocyte_morpholog1.02477068
54MP0004185_abnormal_adipocyte_glucose0.98438842
55MP0004782_abnormal_surfactant_physiolog0.98375798
56MP0003300_gastrointestinal_ulcer0.97427723
57MP0010030_abnormal_orbit_morphology0.97298607
58MP0000470_abnormal_stomach_morphology0.91848038
59MP0008260_abnormal_autophagy0.91415985
60MP0006054_spinal_hemorrhage0.91034177
61MP0000490_abnormal_crypts_of0.89789555
62MP0001666_abnormal_nutrient_absorption0.87877776
63MP0003436_decreased_susceptibility_to0.87781390
64MP0004272_abnormal_basement_membrane0.85827919
65MP0000678_abnormal_parathyroid_gland0.83380627
66MP0003315_abnormal_perineum_morphology0.83270405
67MP0002148_abnormal_hypersensitivity_rea0.82851032
68MP0002006_tumorigenesis0.82553743
69MP0000477_abnormal_intestine_morphology0.81320506
70MP0005377_hearing/vestibular/ear_phenot0.80841502
71MP0003878_abnormal_ear_physiology0.80841502
72MP0004019_abnormal_vitamin_homeostasis0.80308605
73MP0001340_abnormal_eyelid_morphology0.77220484
74MP0000613_abnormal_salivary_gland0.77176061
75MP0002009_preneoplasia0.73027698
76MP0005076_abnormal_cell_differentiation0.71728125
77MP0003191_abnormal_cellular_cholesterol0.70998466
78MP0005381_digestive/alimentary_phenotyp0.67141258
79MP0001188_hyperpigmentation0.65041304
80MP0005499_abnormal_olfactory_system0.64288632
81MP0005394_taste/olfaction_phenotype0.64288632
82MP0000858_altered_metastatic_potential0.64190749
83MP0000003_abnormal_adipose_tissue0.64081112
84MP0002233_abnormal_nose_morphology0.62983214
85MP0002089_abnormal_postnatal_growth/wei0.62728095
86MP0005083_abnormal_biliary_tract0.60653816
87MP0002177_abnormal_outer_ear0.60185567
88MP0005451_abnormal_body_composition0.58737764
89MP0000432_abnormal_head_morphology0.57364771
90MP0006138_congestive_heart_failure0.57264243
91MP0009384_cardiac_valve_regurgitation0.56766663
92MP0002249_abnormal_larynx_morphology0.55648413
93MP0001873_stomach_inflammation0.55641556
94MP0002896_abnormal_bone_mineralization0.55602668
95MP0003755_abnormal_palate_morphology0.54528836
96MP0003091_abnormal_cell_migration0.54173448
97MP0005248_abnormal_Harderian_gland0.53580347
98MP0001663_abnormal_digestive_system0.52927336
99MP0000013_abnormal_adipose_tissue0.52453429
100MP0003448_altered_tumor_morphology0.52439295
101MP0005375_adipose_tissue_phenotype0.50715847
102MP0009785_altered_susceptibility_to0.49912177
103MP0003045_fibrosis0.48953447
104MP0005025_abnormal_response_to0.47452448
105MP0005257_abnormal_intraocular_pressure0.46968899
106MP0002111_abnormal_tail_morphology0.46711720
107MP0005409_darkened_coat_color0.46146932
108MP0005164_abnormal_response_to0.45274332
109MP0002166_altered_tumor_susceptibility0.45208423
110MP0001299_abnormal_eye_distance/0.45170838
111MP0001533_abnormal_skeleton_physiology0.43622577
112MP0002282_abnormal_trachea_morphology0.43516274
113MP0005193_abnormal_anterior_eye0.42806744
114MP0003763_abnormal_thymus_physiology0.42658686
115MP0002095_abnormal_skin_pigmentation0.42584082
116MP0003638_abnormal_response/metabolism_0.41706771
117MP0004197_abnormal_fetal_growth/weight/0.41590601
118MP0005330_cardiomyopathy0.41014824
119MP0002697_abnormal_eye_size0.40861237
120MP0005666_abnormal_adipose_tissue0.39334352
121MP0001784_abnormal_fluid_regulation0.39130088
122MP0001661_extended_life_span0.38746633
123MP0005197_abnormal_uvea_morphology0.37879289
124MP0005621_abnormal_cell_physiology0.36944415
125MP0003786_premature_aging0.36934368
126MP0001765_abnormal_ion_homeostasis0.36509015
127MP0001958_emphysema0.35786112
128MP0001881_abnormal_mammary_gland0.34758479
129MP0002086_abnormal_extraembryonic_tissu0.33473795
130MP0003828_pulmonary_edema0.32870609
131MP0005075_abnormal_melanosome_morpholog0.31603246
132MP0004883_abnormal_blood_vessel0.29654764

Predicted human phenotypes

RankGene SetZ-score
1Onycholysis (HP:0001806)8.84231674
2Milia (HP:0001056)8.34086176
3Fragile nails (HP:0001808)8.18559682
4Plantar hyperkeratosis (HP:0007556)7.53366031
5Atrophic scars (HP:0001075)6.32463410
6Right ventricular cardiomyopathy (HP:0011663)5.98318406
7Pili torti (HP:0003777)5.55260164
8Woolly hair (HP:0002224)5.43341586
9Hypotrichosis (HP:0001006)5.39094556
10Palmoplantar hyperkeratosis (HP:0000972)5.15779019
11Thick nail (HP:0001805)5.01283637
12Palmar hyperkeratosis (HP:0010765)4.86832817
13Nail dystrophy (HP:0008404)4.74434625
14Abnormality of nail color (HP:0100643)4.49215513
15Aplasia cutis congenita (HP:0001057)4.46928618
16Abnormal blistering of the skin (HP:0008066)4.46274943
17Alopecia of scalp (HP:0002293)4.19600459
18Lip pit (HP:0100267)3.84938533
19Amelogenesis imperfecta (HP:0000705)3.81105703
20Increased IgE level (HP:0003212)3.73791702
21Fragile skin (HP:0001030)3.64212455
22Hypoplasia of dental enamel (HP:0006297)3.46056561
23Selective tooth agenesis (HP:0001592)3.41751032
24Parakeratosis (HP:0001036)3.41440779
25Ectropion (HP:0000656)3.38517388
26Abnormal hair laboratory examination (HP:0003328)3.31516957
27Ridged nail (HP:0001807)3.26816856
28Abnormality of the salivary glands (HP:0010286)3.24482087
29Curly hair (HP:0002212)3.09096892
30Esophageal atresia (HP:0002032)2.99882193
31Congenital ichthyosiform erythroderma (HP:0007431)2.98740092
32Erythema (HP:0010783)2.93433475
33Sparse eyelashes (HP:0000653)2.86153101
34Pustule (HP:0200039)2.85522680
35Distal lower limb muscle weakness (HP:0009053)2.82724559
36Dry hair (HP:0011359)2.81386396
37Absent eyelashes (HP:0000561)2.65101568
38Pterygium (HP:0001059)2.62524202
39Erythroderma (HP:0001019)2.58191837
40Blepharitis (HP:0000498)2.56455826
41Premature loss of primary teeth (HP:0006323)2.53536562
42Ureteral stenosis (HP:0000071)2.51902475
43Sparse scalp hair (HP:0002209)2.49066181
44Corneal erosion (HP:0200020)2.46161490
45Ventricular tachycardia (HP:0004756)2.45139365
46Abnormality of placental membranes (HP:0011409)2.44303314
47Amniotic constriction ring (HP:0009775)2.44303314
48Fatigable weakness (HP:0003473)2.42497402
49Abnormality of the neuromuscular junction (HP:0003398)2.42497402
50Cheilitis (HP:0100825)2.41402149
51Oral leukoplakia (HP:0002745)2.41008500
52Abnormality of the gastric mucosa (HP:0004295)2.35494483
53Ureteral obstruction (HP:0006000)2.32833833
54Advanced eruption of teeth (HP:0006288)2.32180239
55Gangrene (HP:0100758)2.30118990
56Conjunctival hamartoma (HP:0100780)2.29026433
57Oligodontia (HP:0000677)2.21141249
58Abnormality of the nasal septum (HP:0000419)2.20844975
59Pruritus (HP:0000989)2.20789986
60Rectal prolapse (HP:0002035)2.20722599
61Palmoplantar keratoderma (HP:0000982)2.19907101
62Popliteal pterygium (HP:0009756)2.17653342
63Abnormality of oral frenula (HP:0000190)2.17463266
64Broad face (HP:0000283)2.17457244
65Natal tooth (HP:0000695)2.16566524
66Dehydration (HP:0001944)2.14633653
67Eczematoid dermatitis (HP:0000976)2.13114158
68Breast hypoplasia (HP:0003187)2.11630817
69Hypodontia (HP:0000668)2.07085076
70Hypohidrosis (HP:0000966)2.06521740
71Laryngomalacia (HP:0001601)2.04997305
72Anonychia (HP:0001798)2.04610594
73Skin ulcer (HP:0200042)2.04311139
74Congenital, generalized hypertrichosis (HP:0004540)2.03738520
75Abnormality of secondary sexual hair (HP:0009888)2.02069799
76Abnormality of the axillary hair (HP:0100134)2.02069799
77Carious teeth (HP:0000670)2.00947559
78Abnormality of the distal phalanges of the toes (HP:0010182)1.98138185
79Increased connective tissue (HP:0009025)1.97768169
80Abnormality of the dental root (HP:0006486)1.97674918
81Taurodontia (HP:0000679)1.97674918
82Abnormality of permanent molar morphology (HP:0011071)1.97674918
83Epidermoid cyst (HP:0200040)1.97139516
84Septate vagina (HP:0001153)1.94360876
85Neonatal death (HP:0003811)1.91020041
86Abnormality of the fingernails (HP:0001231)1.90712640
87Duplicated collecting system (HP:0000081)1.90036068
88Follicular hyperkeratosis (HP:0007502)1.89421015
89Labial hypoplasia (HP:0000066)1.88987690
90Orchitis (HP:0100796)1.87741111
91Hyperhidrosis (HP:0000975)1.86722822
92Short nail (HP:0001799)1.86247820
93Poikiloderma (HP:0001029)1.83521693
94Acanthosis nigricans (HP:0000956)1.82510617
95Abnormality of molar morphology (HP:0011070)1.81323382
96Abnormality of molar (HP:0011077)1.81323382
97Split foot (HP:0001839)1.81301363
98Ileus (HP:0002595)1.80977383
99Unilateral renal agenesis (HP:0000122)1.78592049
100Ureteral duplication (HP:0000073)1.77535543
101Down-sloping shoulders (HP:0200021)1.76174616
102Hypoplastic female external genitalia (HP:0012815)1.75038033
103Ankyloglossia (HP:0010296)1.74683461
104Hypoplasia of the uterus (HP:0000013)1.74463358
105Hypoplastic labia majora (HP:0000059)1.73691107
106Conical tooth (HP:0000698)1.71243906
107Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.71035425
108Abnormality of the dental pulp (HP:0006479)1.69422177
109Periodontitis (HP:0000704)1.69333264
110Abnormality of the lacrimal duct (HP:0011481)1.68542975
111Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.67903206
112Trismus (HP:0000211)1.65322124
113Multifactorial inheritance (HP:0001426)1.65176031
114Flat acetabular roof (HP:0003180)1.61781583
115Interstitial pulmonary disease (HP:0006530)1.61680884
116Symphalangism affecting the phalanges of the hand (HP:0009773)1.61642182
117Ventricular fibrillation (HP:0001663)1.60937161
118Hyporeflexia of lower limbs (HP:0002600)1.60486583
119Prostate neoplasm (HP:0100787)1.59688380
120Abnormality of hair growth rate (HP:0011363)1.58913730
121Slow-growing hair (HP:0002217)1.58913730
122Gastrointestinal atresia (HP:0002589)1.58189351
123Pyloric stenosis (HP:0002021)1.54892124
124Distal lower limb amyotrophy (HP:0008944)1.54799717
125Abnormality of the labia majora (HP:0012881)1.53418172
126Myositis (HP:0100614)1.52887774
127Abnormal hemoglobin (HP:0011902)1.50624136
128Nasolacrimal duct obstruction (HP:0000579)1.50412615
129Xerostomia (HP:0000217)1.49768685
130Absent eyebrow (HP:0002223)1.44064741
131Hyperactive renin-angiotensin system (HP:0000841)1.42734048
132Sepsis (HP:0100806)1.42067356
133Abdominal distention (HP:0003270)1.41418749
134Micronodular cirrhosis (HP:0001413)1.40942142

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R6.00743381
2EPHA25.70542725
3MST43.83264621
4LATS13.10714359
5MAP3K33.03482165
6EPHB23.01637749
7SIK12.94190539
8FER2.64674245
9MAP3K92.44080688
10MAPKAPK32.40277330
11EPHA32.30848171
12NTRK12.30245839
13FRK2.15454135
14MAP3K22.14437170
15FLT32.07954168
16RPS6KB22.02888310
17ARAF1.96997373
18EPHB11.92019220
19MET1.91997426
20ERN11.91020235
21MAP2K21.79902434
22NME11.62653752
23MAP3K61.61942491
24TRPM71.59424268
25BLK1.56907675
26PDGFRA1.52817633
27STK241.43549620
28PTK61.41536019
29RIPK11.34896482
30STK101.33900198
31CDK121.32052506
32NUAK11.24034769
33PIK3CG1.23221339
34MAP3K141.23109415
35NME21.18596911
36STK31.17847764
37PIM21.15660888
38SMG11.13974214
39LMTK21.09172782
40PIK3CA1.07817993
41BMPR1B1.06639399
42MAP3K11.05346109
43PTK21.04844386
44ERBB31.02676816
45TGFBR21.02083683
46MAP2K61.00179690
47LRRK20.99878850
48FGFR40.99224062
49CDK60.98981770
50MAP3K110.95176391
51PBK0.93041359
52PRKG20.89181726
53MAPKAPK20.88287926
54MAP3K130.88094964
55MAP2K10.87053229
56ERBB20.86446577
57MAPK150.85655268
58PDGFRB0.85557264
59DMPK0.84595909
60TYK20.81917695
61BCR0.80613436
62SIK30.78375599
63FGFR30.77831747
64MAP3K120.75842445
65ICK0.75351123
66FGFR20.74365849
67RPS6KA40.72560139
68EEF2K0.72527660
69BMX0.71172365
70STK38L0.70201459
71NLK0.69974110
72TESK10.69688065
73ZAK0.68156268
74FGFR10.65897881
75PRKD20.65875699
76IRAK30.64106137
77STK380.60648069
78MTOR0.60577237
79TRIB30.60335547
80MOS0.58334291
81DDR20.58052038
82RIPK40.56842152
83PHKG10.55737899
84PHKG20.55737899
85MATK0.55129364
86PRPF4B0.53346753
87TAOK10.51577692
88RPS6KA20.51090474
89IKBKE0.50473708
90CDC42BPA0.50036758
91PRKCI0.49100416
92CHUK0.47740618
93IRAK10.47118714
94TBK10.46900888
95TTN0.46703511
96PAK40.45503618
97MAPKAPK50.43734295
98TGFBR10.42483592
99JAK10.42446878
100TXK0.38744874
101EIF2AK20.37318304
102CSK0.36762189
103IKBKB0.36439734
104RAF10.36126097
105BRAF0.34980289
106MARK20.34302777
107KSR20.34124400
108HCK0.33129136
109PTK2B0.33081011
110MAP3K70.30072427
111ERBB40.29687047
112ITK0.29398158
113ADRBK10.28922240
114TAOK20.28101548
115GRK70.27970875
116CDK30.26597903
117JAK30.26527635
118IGF1R0.26285919
119WNK10.26053703
120DYRK1B0.25509180
121GRK10.25200783
122CSF1R0.25176678
123PKN20.23931175
124MAP2K30.23537903
125GSK3A0.23245155
126MUSK0.22239892
127MAP3K80.22186219
128IRAK40.21799010
129AURKB0.21769485
130ROCK20.21501899
131BTK0.21218919
132MAPK110.21018481
133PRKCE0.21006208
134MAP4K10.20985716
135ABL20.20905084
136RPS6KA10.19683340
137LATS20.19518183
138KSR10.19005196
139NEK60.18168807
140ZAP700.16416338
141SGK30.15309046
142RPS6KC10.15062649
143RPS6KL10.15062649

Predicted pathways (KEGG)

RankGene SetZ-score
1Mineral absorption_Homo sapiens_hsa049782.60737487
2ECM-receptor interaction_Homo sapiens_hsa045122.41787608
3alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.18249663
4Linoleic acid metabolism_Homo sapiens_hsa005912.16456637
5Notch signaling pathway_Homo sapiens_hsa043302.15538844
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.99781087
7Fat digestion and absorption_Homo sapiens_hsa049751.97450610
8Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.86155610
9Arachidonic acid metabolism_Homo sapiens_hsa005901.83688576
10Adherens junction_Homo sapiens_hsa045201.80914901
11Sphingolipid metabolism_Homo sapiens_hsa006001.79968410
12Central carbon metabolism in cancer_Homo sapiens_hsa052301.74991298
13Sulfur metabolism_Homo sapiens_hsa009201.74541595
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.73678431
15Toxoplasmosis_Homo sapiens_hsa051451.72558711
16Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.72110703
17Basal cell carcinoma_Homo sapiens_hsa052171.71654513
18Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.67303628
19Small cell lung cancer_Homo sapiens_hsa052221.62833089
20Amoebiasis_Homo sapiens_hsa051461.58244070
21ErbB signaling pathway_Homo sapiens_hsa040121.53415098
22Hematopoietic cell lineage_Homo sapiens_hsa046401.51135927
23Circadian rhythm_Homo sapiens_hsa047101.48741462
24Bladder cancer_Homo sapiens_hsa052191.46107058
25Histidine metabolism_Homo sapiens_hsa003401.44725512
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.43719477
27Caffeine metabolism_Homo sapiens_hsa002321.41464240
28Hippo signaling pathway_Homo sapiens_hsa043901.37869353
29Dorso-ventral axis formation_Homo sapiens_hsa043201.35243939
30Tight junction_Homo sapiens_hsa045301.34073762
31Cyanoamino acid metabolism_Homo sapiens_hsa004601.32758200
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.32553451
33Proteoglycans in cancer_Homo sapiens_hsa052051.30785919
34Chronic myeloid leukemia_Homo sapiens_hsa052201.27251829
35Ribosome_Homo sapiens_hsa030101.24477345
36Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.24205973
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.23953819
38Steroid biosynthesis_Homo sapiens_hsa001001.22755417
39Leishmaniasis_Homo sapiens_hsa051401.22687472
40Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.19790819
41Ether lipid metabolism_Homo sapiens_hsa005651.19631544
42Protein digestion and absorption_Homo sapiens_hsa049741.19299701
43Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.13784546
44Jak-STAT signaling pathway_Homo sapiens_hsa046301.13154850
45Vitamin digestion and absorption_Homo sapiens_hsa049771.12842293
46Thyroid cancer_Homo sapiens_hsa052161.11690732
47Osteoclast differentiation_Homo sapiens_hsa043801.10538336
48Renin-angiotensin system_Homo sapiens_hsa046141.09888164
49Hepatitis C_Homo sapiens_hsa051601.09400649
50TNF signaling pathway_Homo sapiens_hsa046681.08869121
51Galactose metabolism_Homo sapiens_hsa000521.08730442
52Pertussis_Homo sapiens_hsa051331.08549691
53NOD-like receptor signaling pathway_Homo sapiens_hsa046211.08400150
54Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07418262
55Toll-like receptor signaling pathway_Homo sapiens_hsa046201.05757760
56Salmonella infection_Homo sapiens_hsa051321.05403308
57Inositol phosphate metabolism_Homo sapiens_hsa005621.04529413
58PI3K-Akt signaling pathway_Homo sapiens_hsa041511.01820797
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99730682
60Focal adhesion_Homo sapiens_hsa045100.98928566
61Fatty acid biosynthesis_Homo sapiens_hsa000610.98566690
62Phenylalanine metabolism_Homo sapiens_hsa003600.98046555
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.97492327
64Axon guidance_Homo sapiens_hsa043600.96104363
65VEGF signaling pathway_Homo sapiens_hsa043700.95974916
66Endocytosis_Homo sapiens_hsa041440.95777931
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.93878505
68Influenza A_Homo sapiens_hsa051640.93640972
69Insulin signaling pathway_Homo sapiens_hsa049100.93425648
70Dilated cardiomyopathy_Homo sapiens_hsa054140.93424904
71Pancreatic secretion_Homo sapiens_hsa049720.90854206
72NF-kappa B signaling pathway_Homo sapiens_hsa040640.89613727
73Endometrial cancer_Homo sapiens_hsa052130.88827687
74Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88702992
75Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88408421
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.86821124
77Acute myeloid leukemia_Homo sapiens_hsa052210.86123205
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.85775241
79Renal cell carcinoma_Homo sapiens_hsa052110.84641468
80Hedgehog signaling pathway_Homo sapiens_hsa043400.81996766
81Malaria_Homo sapiens_hsa051440.79903716
82Glioma_Homo sapiens_hsa052140.79646668
83Wnt signaling pathway_Homo sapiens_hsa043100.78184209
84Legionellosis_Homo sapiens_hsa051340.77988714
85Fructose and mannose metabolism_Homo sapiens_hsa000510.77983267
86Tuberculosis_Homo sapiens_hsa051520.77645049
87Apoptosis_Homo sapiens_hsa042100.75829085
88Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73152233
89Ovarian steroidogenesis_Homo sapiens_hsa049130.72801983
90Staphylococcus aureus infection_Homo sapiens_hsa051500.71580661
91Estrogen signaling pathway_Homo sapiens_hsa049150.71524390
92Retinol metabolism_Homo sapiens_hsa008300.71506452
93Regulation of actin cytoskeleton_Homo sapiens_hsa048100.71026193
94MicroRNAs in cancer_Homo sapiens_hsa052060.70326523
95Pathways in cancer_Homo sapiens_hsa052000.70226915
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69936450
97p53 signaling pathway_Homo sapiens_hsa041150.69094044
98Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67703729
99Intestinal immune network for IgA production_Homo sapiens_hsa046720.67500884
100Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.67222867
101AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66797734
102Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.66138693
103TGF-beta signaling pathway_Homo sapiens_hsa043500.66047944
104Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.65568290
105GnRH signaling pathway_Homo sapiens_hsa049120.64485486
106Insulin resistance_Homo sapiens_hsa049310.64039325
107Glucagon signaling pathway_Homo sapiens_hsa049220.63718051
108Glycerophospholipid metabolism_Homo sapiens_hsa005640.63660576
109Choline metabolism in cancer_Homo sapiens_hsa052310.63163161
110Chemical carcinogenesis_Homo sapiens_hsa052040.62337935
111Glutathione metabolism_Homo sapiens_hsa004800.62172751
112Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61734181
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.60495332
114Platelet activation_Homo sapiens_hsa046110.57456107
115Glycerolipid metabolism_Homo sapiens_hsa005610.56426104
116Melanogenesis_Homo sapiens_hsa049160.55965722
117Prolactin signaling pathway_Homo sapiens_hsa049170.54468322
118Shigellosis_Homo sapiens_hsa051310.53677986
119Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53121108
120Arginine biosynthesis_Homo sapiens_hsa002200.53076357
121Rap1 signaling pathway_Homo sapiens_hsa040150.52989935
122ABC transporters_Homo sapiens_hsa020100.52303742
123African trypanosomiasis_Homo sapiens_hsa051430.50980587
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.50896737
125Pentose phosphate pathway_Homo sapiens_hsa000300.50428526
126Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49524256
127AMPK signaling pathway_Homo sapiens_hsa041520.47716839
128Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.47557654
129Melanoma_Homo sapiens_hsa052180.47349723
130Pancreatic cancer_Homo sapiens_hsa052120.46924897
131Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.46567678
132Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46529011
133N-Glycan biosynthesis_Homo sapiens_hsa005100.44020253
134Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.43792774
135Prion diseases_Homo sapiens_hsa050200.43056497
136Adipocytokine signaling pathway_Homo sapiens_hsa049200.42031137
137Neurotrophin signaling pathway_Homo sapiens_hsa047220.39316479
138Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39051517
139Non-small cell lung cancer_Homo sapiens_hsa052230.38392591
140Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.38380356
141Long-term depression_Homo sapiens_hsa047300.34579656
142Ras signaling pathway_Homo sapiens_hsa040140.33811802
143Phospholipase D signaling pathway_Homo sapiens_hsa040720.33090145
144Renin secretion_Homo sapiens_hsa049240.32091997
145mTOR signaling pathway_Homo sapiens_hsa041500.31579965
146Tyrosine metabolism_Homo sapiens_hsa003500.28589430

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »