TOM1L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1doxorubicin metabolic process (GO:0044598)5.07566821
2daunorubicin metabolic process (GO:0044597)5.07566821
3polyketide metabolic process (GO:0030638)5.07566821
4cysteine metabolic process (GO:0006534)4.94870754
5ethanol oxidation (GO:0006069)4.81538634
6response to nitrosative stress (GO:0051409)4.45646263
7sulfur amino acid catabolic process (GO:0000098)4.29999598
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.97594174
9serine family amino acid catabolic process (GO:0009071)3.96048364
10gap junction assembly (GO:0016264)3.96004797
11amino-acid betaine metabolic process (GO:0006577)3.93946338
12carnitine metabolic process (GO:0009437)3.82430886
13primary alcohol catabolic process (GO:0034310)3.64299464
14serine family amino acid metabolic process (GO:0009069)3.63167373
15lysine catabolic process (GO:0006554)3.62953584
16lysine metabolic process (GO:0006553)3.62953584
17serine family amino acid biosynthetic process (GO:0009070)3.57951219
18renal absorption (GO:0070293)3.56424680
19glycine metabolic process (GO:0006544)3.56081965
20homocysteine metabolic process (GO:0050667)3.53916799
21one-carbon compound transport (GO:0019755)3.52356779
22intestinal cholesterol absorption (GO:0030299)3.47723966
23lactate metabolic process (GO:0006089)3.44380901
24short-chain fatty acid metabolic process (GO:0046459)3.38949066
25regulation of cholesterol esterification (GO:0010872)3.38135723
26aminoglycoside antibiotic metabolic process (GO:0030647)3.38052595
27ethanol metabolic process (GO:0006067)3.30631658
28keratinocyte development (GO:0003334)3.30278583
29reverse cholesterol transport (GO:0043691)3.29756828
30protoporphyrinogen IX metabolic process (GO:0046501)3.23915281
31very-low-density lipoprotein particle assembly (GO:0034379)3.23479027
32high-density lipoprotein particle remodeling (GO:0034375)3.20953145
33cellular glucuronidation (GO:0052695)3.20162021
34atrial cardiac muscle cell action potential (GO:0086014)3.18927553
35paraxial mesoderm development (GO:0048339)3.12144049
36L-serine metabolic process (GO:0006563)3.12114517
37bundle of His cell to Purkinje myocyte communication (GO:0086069)3.09198772
38cellular modified amino acid catabolic process (GO:0042219)3.06112174
39branched-chain amino acid catabolic process (GO:0009083)3.04819448
40hormone catabolic process (GO:0042447)3.03945171
41glyoxylate metabolic process (GO:0046487)3.02750178
42alpha-linolenic acid metabolic process (GO:0036109)3.01222436
43purine nucleobase biosynthetic process (GO:0009113)2.98399881
44negative regulation of astrocyte differentiation (GO:0048712)2.98263782
45low-density lipoprotein particle remodeling (GO:0034374)2.94590943
46positive regulation of mitotic sister chromatid separation (GO:1901970)2.94173335
47positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.94173335
48positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.94173335
49erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.92682675
50L-phenylalanine catabolic process (GO:0006559)2.92682675
51glucuronate metabolic process (GO:0019585)2.92071529
52uronic acid metabolic process (GO:0006063)2.92071529
53purine ribonucleotide transport (GO:0015868)2.91965563
54protoporphyrinogen IX biosynthetic process (GO:0006782)2.89656334
55erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.88859059
56L-phenylalanine metabolic process (GO:0006558)2.88859059
57aspartate family amino acid catabolic process (GO:0009068)2.86846176
58regulation of cholesterol biosynthetic process (GO:0045540)2.84700500
59intestinal absorption (GO:0050892)2.83680267
60protein-lipid complex remodeling (GO:0034368)2.83289570
61macromolecular complex remodeling (GO:0034367)2.83289570
62plasma lipoprotein particle remodeling (GO:0034369)2.83289570
63protein K6-linked ubiquitination (GO:0085020)2.82741058
64respiratory chain complex IV assembly (GO:0008535)2.82501298
65adenine nucleotide transport (GO:0051503)2.78016877
66cellular amino acid catabolic process (GO:0009063)2.77637108
67regulation of glucokinase activity (GO:0033131)2.74476564
68regulation of hexokinase activity (GO:1903299)2.74476564
69IMP biosynthetic process (GO:0006188)2.70585934
70regulation of acrosome reaction (GO:0060046)2.70545783
71purine nucleotide transport (GO:0015865)2.70259970
72plasma lipoprotein particle assembly (GO:0034377)2.69626307
73coenzyme catabolic process (GO:0009109)2.68966723
74bile acid biosynthetic process (GO:0006699)2.68923677
75alpha-amino acid catabolic process (GO:1901606)2.68521593
76regulation of fibrinolysis (GO:0051917)2.65427899
77nucleobase biosynthetic process (GO:0046112)2.63952662
78intestinal epithelial cell development (GO:0060576)2.63776497
79peptide catabolic process (GO:0043171)2.62244214
80proline metabolic process (GO:0006560)2.60055223
81positive regulation of chromosome segregation (GO:0051984)2.59659841
82branched-chain amino acid metabolic process (GO:0009081)2.58472519
83zinc ion transport (GO:0006829)2.57813006
84negative regulation of keratinocyte proliferation (GO:0010839)2.56263263
85valine metabolic process (GO:0006573)2.56001081
86folic acid-containing compound biosynthetic process (GO:0009396)2.55764146
87desmosome organization (GO:0002934)2.55194365
88genitalia morphogenesis (GO:0035112)2.51938473
89folic acid metabolic process (GO:0046655)2.51537019
90sulfur amino acid metabolic process (GO:0000096)2.51456200
91lipid oxidation (GO:0034440)2.50718662
92xenobiotic catabolic process (GO:0042178)2.50425308
93L-alpha-amino acid transmembrane transport (GO:1902475)2.50280392
94fatty acid beta-oxidation (GO:0006635)2.50102982
95aromatic amino acid family catabolic process (GO:0009074)2.49970316
96AMP metabolic process (GO:0046033)2.49894887
97regulation of type B pancreatic cell apoptotic process (GO:2000674)2.49826316
98water-soluble vitamin biosynthetic process (GO:0042364)2.48928187
99proteasome assembly (GO:0043248)2.48563564
100regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.48326173
101phenylpropanoid metabolic process (GO:0009698)2.47599272
102mitotic metaphase plate congression (GO:0007080)2.47579406
103carboxylic acid catabolic process (GO:0046395)2.45248828
104organic acid catabolic process (GO:0016054)2.45248828
105glutamate metabolic process (GO:0006536)2.44790905
106mitotic sister chromatid cohesion (GO:0007064)2.44742667
107fatty acid oxidation (GO:0019395)2.44281096
108regulation of centriole replication (GO:0046599)2.44052766
109negative regulation of hormone metabolic process (GO:0032351)2.43663507
110one-carbon metabolic process (GO:0006730)2.42284299
111fructose metabolic process (GO:0006000)2.41826384
112regulation of cholesterol metabolic process (GO:0090181)2.41125012
113biotin metabolic process (GO:0006768)2.40879979
114glutathione derivative biosynthetic process (GO:1901687)2.40453853
115glutathione derivative metabolic process (GO:1901685)2.40453853
116DNA double-strand break processing (GO:0000729)2.40417507
117positive regulation of histone H3-K4 methylation (GO:0051571)2.39986582
118plasma lipoprotein particle organization (GO:0071827)2.39880098
119pteridine-containing compound biosynthetic process (GO:0042559)2.39628334
120cellular biogenic amine catabolic process (GO:0042402)2.38133708
121amine catabolic process (GO:0009310)2.38133708
122negative regulation of hormone biosynthetic process (GO:0032353)2.37635439
123ribosome assembly (GO:0042255)2.37188919
124regulation of meiosis I (GO:0060631)2.36128754
125regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.35595440
126kinetochore assembly (GO:0051382)2.35555949
127regulation of bile acid biosynthetic process (GO:0070857)2.34391611
128proline biosynthetic process (GO:0006561)2.34312560
129cullin deneddylation (GO:0010388)2.33975155
130cytochrome complex assembly (GO:0017004)2.29347809
131regulation of mitochondrial translation (GO:0070129)2.29175397
132zinc ion transmembrane transport (GO:0071577)2.28029229
133synapsis (GO:0007129)2.27538276
134epoxygenase P450 pathway (GO:0019373)2.26702726
135UDP-N-acetylglucosamine metabolic process (GO:0006047)2.25863214
136pteridine-containing compound metabolic process (GO:0042558)2.25399957
137retinal metabolic process (GO:0042574)2.25001043
138DNA replication checkpoint (GO:0000076)2.24176053
139positive regulation of glycolytic process (GO:0045821)2.23207477
140heme transport (GO:0015886)2.22867205
141auditory receptor cell differentiation (GO:0042491)2.22488134
142somite rostral/caudal axis specification (GO:0032525)2.21487426
143endocrine pancreas development (GO:0031018)2.18024325
144tetrahydrofolate metabolic process (GO:0046653)2.17320041
145regulation of keratinocyte proliferation (GO:0010837)2.15888183
146nodal signaling pathway (GO:0038092)2.13070014
147meiotic cell cycle (GO:0051321)2.11903661
148COPII vesicle coating (GO:0048208)2.11555586
149glandular epithelial cell differentiation (GO:0002067)2.10113274
150protein autoprocessing (GO:0016540)2.08799963
151nucleotide-sugar biosynthetic process (GO:0009226)2.06680782
152tight junction assembly (GO:0070830)2.06431376
153negative regulation of execution phase of apoptosis (GO:1900118)2.06024956
154positive regulation of macroautophagy (GO:0016239)2.05292470
155protein localization to kinetochore (GO:0034501)2.05056504
156protein deneddylation (GO:0000338)2.04604415
157metaphase plate congression (GO:0051310)2.04223925
158chromatin remodeling at centromere (GO:0031055)2.01447133
159cellular aldehyde metabolic process (GO:0006081)2.01305978
160double-strand break repair via nonhomologous end joining (GO:0006303)2.01095323
161non-recombinational repair (GO:0000726)2.01095323
162rRNA methylation (GO:0031167)1.99586159
163CENP-A containing nucleosome assembly (GO:0034080)1.99014386
164positive regulation of glycoprotein biosynthetic process (GO:0010560)1.98470880
165drug catabolic process (GO:0042737)1.98419236
166regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)1.97046895
167regulation of mitotic spindle checkpoint (GO:1903504)1.97046895
168aldehyde catabolic process (GO:0046185)1.96663573
169cellular ketone body metabolic process (GO:0046950)1.96273395
170establishment of integrated proviral latency (GO:0075713)1.94929148
171oocyte development (GO:0048599)1.94892890
172replication fork processing (GO:0031297)1.94862246
173binding of sperm to zona pellucida (GO:0007339)1.94558517
174nuclear pore organization (GO:0006999)1.91900148
175oxidative demethylation (GO:0070989)1.91093486

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.08733045
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.23091498
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.60942020
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.54930185
5RXR_22158963_ChIP-Seq_LIVER_Mouse3.31724835
6PPARA_22158963_ChIP-Seq_LIVER_Mouse3.21471417
7EGR1_23403033_ChIP-Seq_LIVER_Mouse3.08706422
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.07139950
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.93431757
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.79562436
11LXR_22158963_ChIP-Seq_LIVER_Mouse2.72776928
12E2F7_22180533_ChIP-Seq_HELA_Human2.68616522
13AR_21909140_ChIP-Seq_LNCAP_Human2.63885958
14CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.50047818
15CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.20582420
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.20091085
17FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.09025123
18HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.08935142
19TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.08668910
20EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.07210425
21ESR1_15608294_ChIP-ChIP_MCF-7_Human2.01055282
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.99749592
23ELK1_19687146_ChIP-ChIP_HELA_Human1.91428420
24PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.90713461
25SOX2_18555785_ChIP-Seq_MESCs_Mouse1.90318862
26NELFA_20434984_ChIP-Seq_ESCs_Mouse1.86630840
27FUS_26573619_Chip-Seq_HEK293_Human1.81737269
28POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.81688485
29MYC_19030024_ChIP-ChIP_MESCs_Mouse1.78008205
30TP63_17297297_ChIP-ChIP_HaCaT_Human1.76330985
31POU3F2_20337985_ChIP-ChIP_501MEL_Human1.71962466
32PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.71353277
33* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.70754368
34* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.63161284
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.62594159
36ZNF263_19887448_ChIP-Seq_K562_Human1.62395107
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.57591742
38E2F1_21310950_ChIP-Seq_MCF-7_Human1.57428202
39FOXM1_23109430_ChIP-Seq_U2OS_Human1.57381171
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.57364477
41* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.56885664
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.56561369
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56075320
44CLOCK_20551151_ChIP-Seq_293T_Human1.54132589
45* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.54118813
46GATA4_25053715_ChIP-Seq_YYC3_Human1.51602119
47BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.49645249
48PADI4_21655091_ChIP-ChIP_MCF-7_Human1.48146051
49ZNF217_24962896_ChIP-Seq_MCF-7_Human1.47342967
50AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.47180951
51SALL4_18804426_ChIP-ChIP_XEN_Mouse1.46156627
52* EWS_26573619_Chip-Seq_HEK293_Human1.45768527
53NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.43754551
54HIF1A_21447827_ChIP-Seq_MCF-7_Human1.41234938
55RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.40690568
56SRF_21415370_ChIP-Seq_HL-1_Mouse1.39694176
57PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.36943273
58EST1_17652178_ChIP-ChIP_JURKAT_Human1.36454279
59TCF3_18692474_ChIP-Seq_MEFs_Mouse1.36331079
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.35953538
61NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.35656282
62ELF1_17652178_ChIP-ChIP_JURKAT_Human1.35387215
63STAT3_1855785_ChIP-Seq_MESCs_Mouse1.35385591
64TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33449061
65ZNF274_21170338_ChIP-Seq_K562_Hela1.33365005
66GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.33299557
67JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.32491709
68ESR1_20079471_ChIP-ChIP_T-47D_Human1.29217309
69GABP_17652178_ChIP-ChIP_JURKAT_Human1.28968908
70ESR1_21235772_ChIP-Seq_MCF-7_Human1.28039155
71GBX2_23144817_ChIP-Seq_PC3_Human1.27645781
72MYC_19079543_ChIP-ChIP_MESCs_Mouse1.26709477
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.26279818
74PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.25657884
75NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.24716225
76ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.24022716
77MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.23427371
78CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23244863
79DCP1A_22483619_ChIP-Seq_HELA_Human1.22946955
80MYC_18940864_ChIP-ChIP_HL60_Human1.22486133
81SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.22023774
82GATA1_22025678_ChIP-Seq_K562_Human1.21793954
83HTT_18923047_ChIP-ChIP_STHdh_Human1.20993724
84FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20763591
85* P300_19829295_ChIP-Seq_ESCs_Human1.19049773
86GATA6_25053715_ChIP-Seq_YYC3_Human1.18673074
87* AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.17608034
88ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.17543320
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15690019
90NANOG_21062744_ChIP-ChIP_HESCs_Human1.15556301
91SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.15036499
92STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.14852466
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.14057351
94DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13302390
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.13061609
96VDR_22108803_ChIP-Seq_LS180_Human1.12735416
97NANOG_18555785_ChIP-Seq_MESCs_Mouse1.12014392
98TCF3_18692474_ChIP-Seq_MESCs_Mouse1.11501173
99ZFX_18555785_ChIP-Seq_MESCs_Mouse1.08818481
100* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.08500672
101* CDX2_22108803_ChIP-Seq_LS180_Human1.08115889
102TAF15_26573619_Chip-Seq_HEK293_Human1.07921503
103* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.07769961
104GATA3_24758297_ChIP-Seq_MCF-7_Human1.06561569
105SOX2_16153702_ChIP-ChIP_HESCs_Human1.05904802
106CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.04990538
107IGF1R_20145208_ChIP-Seq_DFB_Human1.04960165
108* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.04885277
109ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.03668402
110FLI1_27457419_Chip-Seq_LIVER_Mouse1.02780640
111HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.02303844
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.01896649
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.00940778
114ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00509048
115SMAD4_21799915_ChIP-Seq_A2780_Human1.00429804
116AR_25329375_ChIP-Seq_VCAP_Human1.00043364
117FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.99837016
118ER_23166858_ChIP-Seq_MCF-7_Human0.99534568
119IRF1_19129219_ChIP-ChIP_H3396_Human0.98586838
120FOXA1_25552417_ChIP-Seq_VCAP_Human0.98190194
121ELF5_23300383_ChIP-Seq_T47D_Human0.97978007
122YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.97740822
123ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.97512159
124FOXA1_25329375_ChIP-Seq_VCAP_Human0.97397746
125FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97397746
126TCF4_22108803_ChIP-Seq_LS180_Human0.97263780
127SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96786790
128* CHD1_26751641_Chip-Seq_LNCaP_Human0.96614478
129ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95981408
130ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.95967895
131FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95226096
132SOX17_20123909_ChIP-Seq_XEN_Mouse0.95205676
133SOX2_18692474_ChIP-Seq_MEFs_Mouse0.95016515
134XRN2_22483619_ChIP-Seq_HELA_Human0.94149448
135* HNF4A_19822575_ChIP-Seq_HepG2_Human0.94142510
136NANOG_16153702_ChIP-ChIP_HESCs_Human0.93922261
137ETS1_20019798_ChIP-Seq_JURKAT_Human0.93132278
138* AR_20517297_ChIP-Seq_VCAP_Human0.93074563
139SOX2_20726797_ChIP-Seq_SW620_Human0.92942267
140TTF2_22483619_ChIP-Seq_HELA_Human0.92797010
141IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.92060202
142CBP_20019798_ChIP-Seq_JUKART_Human0.92060202
143CTBP2_25329375_ChIP-Seq_LNCAP_Human0.90644464
144GATA4_21415370_ChIP-Seq_HL-1_Mouse0.88927424
145ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88232839
146FOXP3_21729870_ChIP-Seq_TREG_Human0.87764216
147AHR_22903824_ChIP-Seq_MCF-7_Human0.87674651
148GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87358312
149HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.87203799
150VDR_23849224_ChIP-Seq_CD4+_Human0.86725662
151KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86423270
152TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.85936822
153SMAD3_21741376_ChIP-Seq_EPCs_Human0.85403390
154FOXM1_26456572_ChIP-Seq_MCF-7_Human0.84959504
155ESR2_21235772_ChIP-Seq_MCF-7_Human0.84879771
156TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.84450147

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.16237342
2MP0005085_abnormal_gallbladder_physiolo3.81478540
3MP0005360_urolithiasis3.72010157
4MP0003806_abnormal_nucleotide_metabolis3.71237800
5MP0005365_abnormal_bile_salt3.64276916
6MP0000566_synostosis2.79012030
7MP0004147_increased_porphyrin_level2.77175606
8MP0008875_abnormal_xenobiotic_pharmacok2.72963947
9MP0009780_abnormal_chondrocyte_physiolo2.50021091
10MP0001666_abnormal_nutrient_absorption2.40014755
11MP0003693_abnormal_embryo_hatching2.23837661
12MP0004264_abnormal_extraembryonic_tissu2.21580637
13MP0010329_abnormal_lipoprotein_level2.12557200
14MP0009697_abnormal_copulation2.11126757
15MP0003195_calcinosis2.10920258
16MP0009384_cardiac_valve_regurgitation2.07527326
17MP0008877_abnormal_DNA_methylation2.05513093
18MP0003252_abnormal_bile_duct2.04295772
19MP0005332_abnormal_amino_acid2.03607610
20MP0010678_abnormal_skin_adnexa2.01195979
21MP0008789_abnormal_olfactory_epithelium1.92386943
22MP0008057_abnormal_DNA_replication1.81585524
23MP0003656_abnormal_erythrocyte_physiolo1.80248834
24MP0008058_abnormal_DNA_repair1.75495176
25MP0003123_paternal_imprinting1.71127953
26MP0002234_abnormal_pharynx_morphology1.68684428
27MP0004043_abnormal_pH_regulation1.67055874
28MP0010352_gastrointestinal_tract_polyps1.66597278
29MP0005379_endocrine/exocrine_gland_phen1.63203477
30MP0003186_abnormal_redox_activity1.61911521
31MP0009053_abnormal_anal_canal1.60447804
32MP0003283_abnormal_digestive_organ1.59257003
33MP0005083_abnormal_biliary_tract1.58168442
34MP0002132_abnormal_respiratory_system1.56122678
35MP0004019_abnormal_vitamin_homeostasis1.51636274
36MP0003878_abnormal_ear_physiology1.51011712
37MP0005377_hearing/vestibular/ear_phenot1.51011712
38MP0003941_abnormal_skin_development1.49131389
39MP0005646_abnormal_pituitary_gland1.47219937
40MP0003718_maternal_effect1.44545990
41MP0005394_taste/olfaction_phenotype1.42805217
42MP0005499_abnormal_olfactory_system1.42805217
43MP0003136_yellow_coat_color1.40876962
44MP0010030_abnormal_orbit_morphology1.38969910
45MP0000383_abnormal_hair_follicle1.37421701
46MP0000516_abnormal_urinary_system1.35837391
47MP0005367_renal/urinary_system_phenotyp1.35837391
48MP0009840_abnormal_foam_cell1.35822994
49MP0002102_abnormal_ear_morphology1.34987781
50MP0005395_other_phenotype1.34742348
51MP0002909_abnormal_adrenal_gland1.31551225
52MP0000537_abnormal_urethra_morphology1.29227055
53MP0002090_abnormal_vision1.29036706
54MP0002877_abnormal_melanocyte_morpholog1.28432786
55MP0002254_reproductive_system_inflammat1.28123224
56MP0006292_abnormal_olfactory_placode1.27992277
57MP0003868_abnormal_feces_composition1.26632773
58MP0001944_abnormal_pancreas_morphology1.25868419
59MP0000427_abnormal_hair_cycle1.23043689
60MP0002938_white_spotting1.21287384
61MP0002163_abnormal_gland_morphology1.20790947
62MP0008932_abnormal_embryonic_tissue1.17522793
63MP0006036_abnormal_mitochondrial_physio1.12247927
64MP0005670_abnormal_white_adipose1.11919072
65MP0005220_abnormal_exocrine_pancreas1.10536481
66MP0002127_abnormal_cardiovascular_syste1.09690389
67MP0002160_abnormal_reproductive_system1.07415699
68MP0005645_abnormal_hypothalamus_physiol1.07263049
69MP0003567_abnormal_fetal_cardiomyocyte1.07057718
70MP0000647_abnormal_sebaceous_gland1.00558208
71MP0009643_abnormal_urine_homeostasis1.00142078
72MP0005636_abnormal_mineral_homeostasis0.98617548
73MP0003121_genomic_imprinting0.97136068
74MP0003937_abnormal_limbs/digits/tail_de0.96687739
75MP0005647_abnormal_sex_gland0.93872945
76MP0002837_dystrophic_cardiac_calcinosis0.93238335
77MP0001756_abnormal_urination0.92842815
78MP0006072_abnormal_retinal_apoptosis0.92686542
79MP0003942_abnormal_urinary_system0.92646114
80MP0001661_extended_life_span0.92357636
81MP0010234_abnormal_vibrissa_follicle0.92171907
82MP0002796_impaired_skin_barrier0.92086657
83MP0003122_maternal_imprinting0.92062698
84MP0003111_abnormal_nucleus_morphology0.90890327
85MP0000462_abnormal_digestive_system0.90673807
86MP0005408_hypopigmentation0.90496718
87MP0005410_abnormal_fertilization0.90162274
88MP0002118_abnormal_lipid_homeostasis0.89984749
89MP0005319_abnormal_enzyme/_coenzyme0.88580814
90MP0000609_abnormal_liver_physiology0.87364887
91MP0001929_abnormal_gametogenesis0.86690256
92MP0004215_abnormal_myocardial_fiber0.86674619
93MP0004957_abnormal_blastocyst_morpholog0.86538444
94MP0010307_abnormal_tumor_latency0.86205476
95MP0002084_abnormal_developmental_patter0.86202287
96MP0005248_abnormal_Harderian_gland0.85819344
97MP0003787_abnormal_imprinting0.84946036
98MP0010094_abnormal_chromosome_stability0.84183616
99MP0001286_abnormal_eye_development0.83886456
100MP0003786_premature_aging0.82758374
101MP0005266_abnormal_metabolism0.82605495
102MP0000579_abnormal_nail_morphology0.82276248
103MP0005389_reproductive_system_phenotype0.82178213
104MP0005187_abnormal_penis_morphology0.81614638
105MP0000538_abnormal_urinary_bladder0.81203848
106MP0002876_abnormal_thyroid_physiology0.80935504
107MP0005551_abnormal_eye_electrophysiolog0.80776360
108MP0001664_abnormal_digestion0.80386561
109MP0002098_abnormal_vibrissa_morphology0.80373458
110MP0001485_abnormal_pinna_reflex0.80141607
111MP0000049_abnormal_middle_ear0.79918683
112MP0002233_abnormal_nose_morphology0.79403660
113MP0009672_abnormal_birth_weight0.77857304
114MP0000653_abnormal_sex_gland0.77471496
115MP0001764_abnormal_homeostasis0.76808914
116MP0000631_abnormal_neuroendocrine_gland0.76633010
117MP0002653_abnormal_ependyma_morphology0.75999721
118MP0000377_abnormal_hair_follicle0.75734315
119MP0010386_abnormal_urinary_bladder0.75339828
120MP0002210_abnormal_sex_determination0.75244951
121MP0001984_abnormal_olfaction0.75225361
122MP0002249_abnormal_larynx_morphology0.75081560
123MP0001324_abnormal_eye_pigmentation0.75029868
124MP0003943_abnormal_hepatobiliary_system0.74716706
125MP0003115_abnormal_respiratory_system0.70971753
126MP0003077_abnormal_cell_cycle0.70117174
127MP0003119_abnormal_digestive_system0.69793590
128MP0000613_abnormal_salivary_gland0.68472144
129MP0001730_embryonic_growth_arrest0.67223512
130MP0004133_heterotaxia0.67215137
131MP0008004_abnormal_stomach_pH0.67020988
132MP0001919_abnormal_reproductive_system0.65575131
133MP0001672_abnormal_embryogenesis/_devel0.65391216
134MP0005380_embryogenesis_phenotype0.65391216
135MP0000762_abnormal_tongue_morphology0.65209972
136MP0002697_abnormal_eye_size0.64694376
137MP0003890_abnormal_embryonic-extraembry0.64075854
138MP0001881_abnormal_mammary_gland0.63951982
139MP0001915_intracranial_hemorrhage0.63784163
140MP0008007_abnormal_cellular_replicative0.62465304
141MP0004885_abnormal_endolymph0.62197639
142MP0003984_embryonic_growth_retardation0.61256711
143MP0000598_abnormal_liver_morphology0.60915969
144MP0001293_anophthalmia0.60880677
145MP0003011_delayed_dark_adaptation0.60298952
146MP0003705_abnormal_hypodermis_morpholog0.60222040
147MP0002086_abnormal_extraembryonic_tissu0.59742484
148MP0000534_abnormal_ureter_morphology0.59296793

Predicted human phenotypes

RankGene SetZ-score
1Hyperlipoproteinemia (HP:0010980)4.26213244
2Hyperglycinemia (HP:0002154)4.05258809
3Hyperglycinuria (HP:0003108)4.05065167
4Hyperinsulinemic hypoglycemia (HP:0000825)3.87461548
5Abnormality of glycine metabolism (HP:0010895)3.68633809
6Abnormality of serine family amino acid metabolism (HP:0010894)3.68633809
7Intrahepatic cholestasis (HP:0001406)3.30918107
8Hypoglycemic coma (HP:0001325)3.27529343
9Hypobetalipoproteinemia (HP:0003563)3.26940104
10Birth length less than 3rd percentile (HP:0003561)3.19710927
11Symptomatic seizures (HP:0011145)3.19295339
12Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.95748928
13Aplasia involving bones of the extremities (HP:0009825)2.91584345
14Aplasia involving bones of the upper limbs (HP:0009823)2.91584345
15Aplasia of the phalanges of the hand (HP:0009802)2.91584345
16Onycholysis (HP:0001806)2.87490630
17Hypolipoproteinemia (HP:0010981)2.84358255
18Poikilocytosis (HP:0004447)2.81786401
19Proximal tubulopathy (HP:0000114)2.80340908
20Hyperammonemia (HP:0001987)2.79682618
21Abnormality of the pancreatic islet cells (HP:0006476)2.74058954
22Abnormality of endocrine pancreas physiology (HP:0012093)2.74058954
23Double outlet right ventricle (HP:0001719)2.72699454
24Congenital malformation of the right heart (HP:0011723)2.72699454
25Abnormality of monocarboxylic acid metabolism (HP:0010996)2.72460365
26Osteomalacia (HP:0002749)2.63193949
27Abnormality of aromatic amino acid family metabolism (HP:0004338)2.58479211
28Median cleft lip (HP:0000161)2.55874874
29Right ventricular cardiomyopathy (HP:0011663)2.54489568
30Hypoalphalipoproteinemia (HP:0003233)2.52188682
31Chromsome breakage (HP:0040012)2.49770890
32Ketoacidosis (HP:0001993)2.49363327
33Pancreatic islet-cell hyperplasia (HP:0004510)2.49346442
34Selective tooth agenesis (HP:0001592)2.48855628
35Enlarged penis (HP:0000040)2.47498966
36Ketosis (HP:0001946)2.45766075
37Abnormality of the labia minora (HP:0012880)2.42550557
38Hypoplastic left heart (HP:0004383)2.41643903
39Abnormality of vitamin B metabolism (HP:0004340)2.40454099
40Acanthocytosis (HP:0001927)2.38378585
41Methylmalonic acidemia (HP:0002912)2.35883229
42Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.31183460
43Hypochromic microcytic anemia (HP:0004840)2.30670008
44Hypothermia (HP:0002045)2.30637236
45Chromosomal breakage induced by crosslinking agents (HP:0003221)2.29895327
46Abnormality of the nasolacrimal system (HP:0000614)2.27672058
47Short middle phalanx of the 5th finger (HP:0004220)2.27419842
48Fat malabsorption (HP:0002630)2.25866394
49Abnormality of serum amino acid levels (HP:0003112)2.25826048
50Hypoplastic labia majora (HP:0000059)2.25519591
51Xanthomatosis (HP:0000991)2.24659614
52Renal tubular acidosis (HP:0001947)2.21606302
53Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.17477094
54Breast hypoplasia (HP:0003187)2.17346823
55Hypokinesia (HP:0002375)2.14684072
56Abnormality of the labia majora (HP:0012881)2.13357193
57Abnormality of sulfur amino acid metabolism (HP:0004339)2.11610628
58Tubulointerstitial nephritis (HP:0001970)2.09775811
59Megaloblastic anemia (HP:0001889)2.08422267
60Neoplasm of the adrenal cortex (HP:0100641)2.07875544
61Abnormality of fatty-acid metabolism (HP:0004359)2.05539667
62Deep venous thrombosis (HP:0002625)2.05317794
63Septate vagina (HP:0001153)2.03582826
64Enlarged kidneys (HP:0000105)2.03307249
65Neoplasm of the adrenal gland (HP:0100631)2.03072580
66Clitoromegaly (HP:0000057)2.02721683
67Breast carcinoma (HP:0003002)2.02715082
68Abnormality of aspartate family amino acid metabolism (HP:0010899)2.02650432
69Aplasia/hypoplasia of the uterus (HP:0008684)2.02035158
70Hyperbilirubinemia (HP:0002904)1.99869800
71Facial cleft (HP:0002006)1.98959887
72Lethargy (HP:0001254)1.97389130
73Dicarboxylic aciduria (HP:0003215)1.96970953
74Abnormality of dicarboxylic acid metabolism (HP:0010995)1.96970953
75Metabolic acidosis (HP:0001942)1.95241595
76Back pain (HP:0003418)1.93506164
77Renal cortical cysts (HP:0000803)1.93473257
78Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.93128392
79Nausea (HP:0002018)1.93074159
80Abnormality of the heme biosynthetic pathway (HP:0010472)1.92929388
81Intestinal atresia (HP:0011100)1.91392298
82Aplasia/Hypoplasia of the tongue (HP:0010295)1.90606432
83Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.90314179
84Abnormality of the vitamin B12 metabolism (HP:0004341)1.90241535
85Chronic hepatic failure (HP:0100626)1.89478054
86Pancreatic fibrosis (HP:0100732)1.88766814
87Abnormality of urine glucose concentration (HP:0011016)1.88124712
88Glycosuria (HP:0003076)1.88124712
89Aplasia cutis congenita (HP:0001057)1.87485223
90Gout (HP:0001997)1.87239879
91Vaginal fistula (HP:0004320)1.87054729
92Abnormality of methionine metabolism (HP:0010901)1.86938248
93Megalencephaly (HP:0001355)1.86763717
94Bifid tongue (HP:0010297)1.86386690
95Aqueductal stenosis (HP:0002410)1.86245917
96Abnormality of the preputium (HP:0100587)1.85073439
97Delayed CNS myelination (HP:0002188)1.84063334
98Methylmalonic aciduria (HP:0012120)1.83855891
99Abnormality of the phalanges of the 5th finger (HP:0004213)1.83425307
100Ileus (HP:0002595)1.83194001
101Microglossia (HP:0000171)1.82702275
102Malnutrition (HP:0004395)1.82560156
103Reticulocytosis (HP:0001923)1.82527736
104Abnormality of cochlea (HP:0000375)1.82474430
105Bronchomalacia (HP:0002780)1.82394864
106Abnormality of abdominal situs (HP:0011620)1.81768653
107Abdominal situs inversus (HP:0003363)1.81768653
108Azoospermia (HP:0000027)1.81731718
109Hypoplastic heart (HP:0001961)1.80812919
110Fibular aplasia (HP:0002990)1.80807515
111Abnormality of vitamin metabolism (HP:0100508)1.80143670
112Insulin-resistant diabetes mellitus (HP:0000831)1.80133163
113Abnormality of glutamine family amino acid metabolism (HP:0010902)1.79987162
114Popliteal pterygium (HP:0009756)1.79920100
115Pancreatic cysts (HP:0001737)1.79808158
116Absent hair (HP:0002298)1.79185213
117Bifid scrotum (HP:0000048)1.78882409
118Abnormality of the astrocytes (HP:0100707)1.78684380
119Astrocytoma (HP:0009592)1.78684380
120Abnormality of the dental pulp (HP:0006479)1.78282743
121True hermaphroditism (HP:0010459)1.77154988
122Hypoglycemic seizures (HP:0002173)1.77101186
123Ependymoma (HP:0002888)1.76850653
124Prolonged partial thromboplastin time (HP:0003645)1.76554926
125Generalized aminoaciduria (HP:0002909)1.76532982
126Impulsivity (HP:0100710)1.76025295
127Abnormality of chromosome stability (HP:0003220)1.75957528
128Abnormal biliary tract morphology (HP:0012440)1.75431319
129Labial hypoplasia (HP:0000066)1.74511997
130Hepatocellular carcinoma (HP:0001402)1.74424660
131Late onset (HP:0003584)1.73999395
132Bile duct proliferation (HP:0001408)1.73527132
133Abnormal biliary tract physiology (HP:0012439)1.73527132
134Absent eyelashes (HP:0000561)1.73312443
135Abnormality of the proximal phalanges of the hand (HP:0009834)1.73195696
136Abnormality of secondary sexual hair (HP:0009888)1.73179885
137Abnormality of the axillary hair (HP:0100134)1.73179885
138Acute encephalopathy (HP:0006846)1.73172964
139Meckel diverticulum (HP:0002245)1.71728111
140Abnormality of the nasal septum (HP:0000419)1.70923856
141Hypoplasia of the uterus (HP:0000013)1.70846936
142Occipital encephalocele (HP:0002085)1.70819783
143Hyperglycemia (HP:0003074)1.70459857
144Hypoplastic female external genitalia (HP:0012815)1.70290522
145Prominent metopic ridge (HP:0005487)1.69458625
146Humeroradial synostosis (HP:0003041)1.69427642
147Synostosis involving the elbow (HP:0003938)1.69427642
148Adrenal hypoplasia (HP:0000835)1.67532500
149Conjugated hyperbilirubinemia (HP:0002908)1.67458336
150Hypoplasia of the fovea (HP:0007750)1.66951762
151Aplasia/Hypoplasia of the fovea (HP:0008060)1.66951762
152Hypophosphatemic rickets (HP:0004912)1.66328461
153Vascular calcification (HP:0004934)1.65826021
154Gastrointestinal atresia (HP:0002589)1.64430218
155Cutaneous melanoma (HP:0012056)1.64393258
156Abnormal pancreas size (HP:0012094)1.63199615
157Abnormality of the labia (HP:0000058)1.62806735
158Conjunctival hamartoma (HP:0100780)1.62481334
159Thyroid carcinoma (HP:0002890)1.62283695
160Increased hepatocellular lipid droplets (HP:0006565)1.62058678
161Glioma (HP:0009733)1.60473150
162Rhabdomyosarcoma (HP:0002859)1.60089361
163Abnormality of the ileum (HP:0001549)1.59814956
164Biliary tract neoplasm (HP:0100574)1.59260834
165Cerebral edema (HP:0002181)1.58768610
166Tongue fasciculations (HP:0001308)1.57959615
167Sex reversal (HP:0012245)1.56256867
168Abnormal sex determination (HP:0012244)1.56256867

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS13.60670343
2BCKDK3.54088096
3MKNK23.07980728
4STK38L2.96530818
5LMTK22.93462869
6EIF2AK12.93015848
7MST42.85166251
8TRIM282.84407150
9AKT32.81686710
10FGFR22.34420048
11EIF2AK32.30217810
12EPHA22.23691302
13CDC72.01645342
14TRPM71.99464967
15WNK31.96277517
16TTK1.90530469
17NEK11.89292163
18MKNK11.87443606
19FRK1.86241914
20STK391.85906679
21ZAK1.79014984
22PIK3CA1.76885120
23MET1.71928692
24NUAK11.68167971
25TSSK61.65322772
26PBK1.63522851
27MAP3K91.52739476
28RPS6KB21.52038958
29SGK21.47673565
30INSRR1.46708643
31BMPR1B1.44944711
32MAP3K121.40008690
33MAPK151.36767454
34SRPK11.36171415
35PASK1.32338745
36BRSK21.29250153
37MAP2K21.20680885
38NME11.20061079
39CSNK1G11.19654090
40VRK21.14960341
41SGK31.11360043
42NEK91.11284542
43CDC42BPA1.10415653
44GRK11.10266592
45OXSR11.09273727
46ERBB41.07706037
47PHKG21.07317667
48PHKG11.07317667
49NLK1.05420158
50PLK41.04987454
51OBSCN1.03604495
52PINK11.03151059
53PNCK1.01573004
54MUSK1.01475395
55STK30.99957064
56TNIK0.98878765
57PLK30.98655629
58AURKB0.98292792
59ACVR1B0.98081875
60PIK3CG0.96725939
61VRK10.95602906
62PLK20.95261068
63STK240.94775410
64PLK10.93926729
65CDK60.92626772
66SIK10.92492837
67MAPKAPK30.91770250
68BCR0.90214301
69WEE10.88266310
70CSNK1G30.87569852
71ERBB20.86933880
72SCYL20.84993636
73MAPK110.84821334
74MELK0.83430390
75BRSK10.82040717
76PRKCE0.81378951
77CAMK1G0.78887427
78FGFR10.77009506
79MYLK0.76625240
80CASK0.76194446
81SGK4940.76093749
82SGK2230.76093749
83PRKG20.74836867
84MAP2K10.72546996
85PDK20.72510569
86PAK20.72434073
87NEK60.71647784
88AURKA0.71451298
89PAK40.71166474
90CHEK20.69441561
91MAP3K20.68292533
92EEF2K0.68087490
93CDK70.67944688
94STK100.67839531
95DYRK30.67468785
96PDK30.65833065
97PDK40.65833065
98PRKCI0.65406735
99BRAF0.65171656
100PRKAA20.63999032
101STK160.63177330
102MAP3K30.62688979
103FER0.62493976
104CDK80.61947493
105CSNK1G20.61358858
106FLT30.61222266
107CSNK1A1L0.61154028
108ATM0.60419756
109MAP2K60.59040670
110CDK40.58743729
111SIK30.57908425
112TAOK30.57689905
113EPHA40.57484905
114AKT20.57178289
115CSNK1E0.56154882
116MST1R0.55801368
117ERBB30.55359365
118IRAK30.55029604
119BRD40.54226958
120PTK60.53655672
121CAMK1D0.53418562
122PTK20.51032173
123PAK30.50625932
124ATR0.48868402
125WNK40.48190070
126EIF2AK20.46440105
127NEK20.46392606
128TLK10.46118149
129PKN20.45588521
130ILK0.44861106
131BUB10.44566158
132LATS20.43798937
133STK40.42689591
134CHEK10.42675758
135CDK30.42178321
136PRKAA10.40941522
137CDK90.40890023
138MAP3K40.40342646
139TGFBR10.40171333
140ARAF0.38595577
141DAPK10.37483015
142YES10.34493588

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.92905224
2Fatty acid degradation_Homo sapiens_hsa000712.87349033
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.52553486
4Propanoate metabolism_Homo sapiens_hsa006402.46306542
5Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.26526136
6Sulfur metabolism_Homo sapiens_hsa009202.23794686
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.23096822
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.22653034
9Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.19920939
10Primary bile acid biosynthesis_Homo sapiens_hsa001202.16068706
11Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.99288710
12Pentose and glucuronate interconversions_Homo sapiens_hsa000401.96815187
13Chemical carcinogenesis_Homo sapiens_hsa052041.79687834
14Maturity onset diabetes of the young_Homo sapiens_hsa049501.76745139
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.72291173
16Folate biosynthesis_Homo sapiens_hsa007901.69851783
17Peroxisome_Homo sapiens_hsa041461.69047731
18Fatty acid metabolism_Homo sapiens_hsa012121.68518394
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.67555651
20Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.66537703
21One carbon pool by folate_Homo sapiens_hsa006701.64477931
22Sulfur relay system_Homo sapiens_hsa041221.62521643
23Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.62153114
24Tryptophan metabolism_Homo sapiens_hsa003801.61628108
25Proteasome_Homo sapiens_hsa030501.61230555
26Non-homologous end-joining_Homo sapiens_hsa034501.58234871
27Pyruvate metabolism_Homo sapiens_hsa006201.55095648
28Carbon metabolism_Homo sapiens_hsa012001.52499374
29Fatty acid biosynthesis_Homo sapiens_hsa000611.49331164
30Cysteine and methionine metabolism_Homo sapiens_hsa002701.48430555
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.46340319
32Glutathione metabolism_Homo sapiens_hsa004801.44302634
33Cyanoamino acid metabolism_Homo sapiens_hsa004601.42825370
34Biosynthesis of amino acids_Homo sapiens_hsa012301.42688020
35beta-Alanine metabolism_Homo sapiens_hsa004101.42279801
36Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.41676553
37Starch and sucrose metabolism_Homo sapiens_hsa005001.41202736
38Fat digestion and absorption_Homo sapiens_hsa049751.39899592
39Arginine biosynthesis_Homo sapiens_hsa002201.37822519
40Selenocompound metabolism_Homo sapiens_hsa004501.37208532
41Drug metabolism - other enzymes_Homo sapiens_hsa009831.35628601
42Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.30414148
43Butanoate metabolism_Homo sapiens_hsa006501.29693077
44Retinol metabolism_Homo sapiens_hsa008301.29515955
45PPAR signaling pathway_Homo sapiens_hsa033201.28339591
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.27764423
47Basal transcription factors_Homo sapiens_hsa030221.25573557
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.22057259
49Galactose metabolism_Homo sapiens_hsa000521.22045877
50Arginine and proline metabolism_Homo sapiens_hsa003301.21702226
51Fanconi anemia pathway_Homo sapiens_hsa034601.19547619
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.16458183
53Tyrosine metabolism_Homo sapiens_hsa003501.15734921
54Histidine metabolism_Homo sapiens_hsa003401.13302196
55Steroid hormone biosynthesis_Homo sapiens_hsa001401.10430419
56Bile secretion_Homo sapiens_hsa049761.05132198
57Fructose and mannose metabolism_Homo sapiens_hsa000511.02536101
58Vitamin B6 metabolism_Homo sapiens_hsa007501.01270107
59Oxidative phosphorylation_Homo sapiens_hsa001901.01001253
60Caffeine metabolism_Homo sapiens_hsa002320.99096235
61Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.94211800
62Mineral absorption_Homo sapiens_hsa049780.92360120
63Mismatch repair_Homo sapiens_hsa034300.92140036
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.91397894
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91199836
66Vitamin digestion and absorption_Homo sapiens_hsa049770.90738830
67Phenylalanine metabolism_Homo sapiens_hsa003600.90619633
68Lysine degradation_Homo sapiens_hsa003100.89322479
69Linoleic acid metabolism_Homo sapiens_hsa005910.88750676
70Complement and coagulation cascades_Homo sapiens_hsa046100.87072486
71Cell cycle_Homo sapiens_hsa041100.80708475
72Sphingolipid metabolism_Homo sapiens_hsa006000.80612951
73Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.78423391
74DNA replication_Homo sapiens_hsa030300.77955515
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76517540
76Pyrimidine metabolism_Homo sapiens_hsa002400.75543877
77Metabolic pathways_Homo sapiens_hsa011000.75469880
78Glycerolipid metabolism_Homo sapiens_hsa005610.75093826
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73846982
80Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.71396380
81Phototransduction_Homo sapiens_hsa047440.69030896
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.65937646
83Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65279444
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65196572
85N-Glycan biosynthesis_Homo sapiens_hsa005100.65102397
86Huntingtons disease_Homo sapiens_hsa050160.64118475
87Base excision repair_Homo sapiens_hsa034100.62420644
88RNA polymerase_Homo sapiens_hsa030200.61724271
89Steroid biosynthesis_Homo sapiens_hsa001000.61580308
90Circadian rhythm_Homo sapiens_hsa047100.60435001
91RNA transport_Homo sapiens_hsa030130.60249653
92Oocyte meiosis_Homo sapiens_hsa041140.58629373
93RNA degradation_Homo sapiens_hsa030180.56531839
94Pentose phosphate pathway_Homo sapiens_hsa000300.55756073
95Arachidonic acid metabolism_Homo sapiens_hsa005900.55588380
96Insulin secretion_Homo sapiens_hsa049110.52555512
97Homologous recombination_Homo sapiens_hsa034400.51652114
98Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.51644973
99Ether lipid metabolism_Homo sapiens_hsa005650.50664523
100Protein export_Homo sapiens_hsa030600.50440620
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47826937
102Nucleotide excision repair_Homo sapiens_hsa034200.47806681
103Thyroid cancer_Homo sapiens_hsa052160.47027747
104Purine metabolism_Homo sapiens_hsa002300.45450846
105ABC transporters_Homo sapiens_hsa020100.43952388
106alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.42875020
107Fatty acid elongation_Homo sapiens_hsa000620.41856602
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41672148
109TGF-beta signaling pathway_Homo sapiens_hsa043500.39863257
110Spliceosome_Homo sapiens_hsa030400.38978911
111Systemic lupus erythematosus_Homo sapiens_hsa053220.38613854
112Protein digestion and absorption_Homo sapiens_hsa049740.38072272
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36595808
114Parkinsons disease_Homo sapiens_hsa050120.35560914
115Renin-angiotensin system_Homo sapiens_hsa046140.34909313
116Hippo signaling pathway_Homo sapiens_hsa043900.33152692
117Basal cell carcinoma_Homo sapiens_hsa052170.32859726
118Tight junction_Homo sapiens_hsa045300.32761500

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