TOMM22

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1formation of translation preinitiation complex (GO:0001731)4.85333123
2maturation of SSU-rRNA (GO:0030490)4.76512480
3chaperone-mediated protein transport (GO:0072321)4.69807186
4viral transcription (GO:0019083)4.57271320
5ribosomal small subunit assembly (GO:0000028)4.57220402
6translational termination (GO:0006415)4.52294912
7proteasome assembly (GO:0043248)4.48656750
8* establishment of protein localization to mitochondrial membrane (GO:0090151)4.45859806
9ribosomal large subunit biogenesis (GO:0042273)4.44711474
10regulation of mitochondrial translation (GO:0070129)4.42271197
11establishment of integrated proviral latency (GO:0075713)4.42103048
12ribosomal small subunit biogenesis (GO:0042274)4.40814859
13negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.28942792
14purine nucleobase biosynthetic process (GO:0009113)4.25973203
15DNA deamination (GO:0045006)4.21734035
16anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.16718138
17positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.16252062
18translational initiation (GO:0006413)4.15645571
19regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.12822274
20translational elongation (GO:0006414)4.10069451
21nucleobase biosynthetic process (GO:0046112)4.08177595
22mitotic metaphase plate congression (GO:0007080)4.06748732
23ribonucleoprotein complex biogenesis (GO:0022613)4.05199515
24ribosome assembly (GO:0042255)3.99752936
25DNA replication checkpoint (GO:0000076)3.99263830
26DNA strand elongation involved in DNA replication (GO:0006271)3.98306792
27respiratory electron transport chain (GO:0022904)3.96644927
28mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.93137923
29negative regulation of ligase activity (GO:0051352)3.92627780
30negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.92627780
31SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.90871506
32electron transport chain (GO:0022900)3.87021596
33cotranslational protein targeting to membrane (GO:0006613)3.84123241
34ribosome biogenesis (GO:0042254)3.83489828
35* protein targeting to mitochondrion (GO:0006626)3.81921580
36protein targeting to ER (GO:0045047)3.81211416
37DNA strand elongation (GO:0022616)3.75659474
38termination of RNA polymerase III transcription (GO:0006386)3.74969105
39transcription elongation from RNA polymerase III promoter (GO:0006385)3.74969105
40nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.74542391
41regulation of cellular amino acid metabolic process (GO:0006521)3.73874764
42spliceosomal snRNP assembly (GO:0000387)3.73874503
43positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.72900462
44DNA replication initiation (GO:0006270)3.72736206
45telomere maintenance via semi-conservative replication (GO:0032201)3.72662783
46DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.71310002
47rRNA processing (GO:0006364)3.67593338
48cellular protein complex disassembly (GO:0043624)3.65909759
49signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.64709890
50intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.64709890
51CENP-A containing nucleosome assembly (GO:0034080)3.64546169
52protein localization to endoplasmic reticulum (GO:0070972)3.63219425
537-methylguanosine mRNA capping (GO:0006370)3.62736877
54establishment of protein localization to endoplasmic reticulum (GO:0072599)3.62162319
55signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.61996483
56signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.61996483
57signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.61996483
58translation (GO:0006412)3.61185819
59oxidative phosphorylation (GO:0006119)3.60981265
60signal transduction involved in DNA damage checkpoint (GO:0072422)3.58144951
61signal transduction involved in DNA integrity checkpoint (GO:0072401)3.58144951
62mitochondrial respiratory chain complex assembly (GO:0033108)3.57938971
63chromatin remodeling at centromere (GO:0031055)3.57144289
64* establishment of protein localization to mitochondrion (GO:0072655)3.56494016
65protein localization to kinetochore (GO:0034501)3.56239881
66positive regulation of ligase activity (GO:0051351)3.56084388
67viral life cycle (GO:0019058)3.56000245
68protein complex biogenesis (GO:0070271)3.55951012
69rRNA metabolic process (GO:0016072)3.55790733
70RNA capping (GO:0036260)3.55711954
717-methylguanosine RNA capping (GO:0009452)3.55711954
72signal transduction involved in cell cycle checkpoint (GO:0072395)3.52496511
73rRNA modification (GO:0000154)3.52339946
74protein neddylation (GO:0045116)3.52179034
75* protein localization to mitochondrion (GO:0070585)3.51851984
76pseudouridine synthesis (GO:0001522)3.47995659
77establishment of viral latency (GO:0019043)3.47165570
78antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.46370044
79cullin deneddylation (GO:0010388)3.41502627
80telomere maintenance via recombination (GO:0000722)3.40689759
81respiratory chain complex IV assembly (GO:0008535)3.40286758
82regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.39325114
83protein localization to chromosome, centromeric region (GO:0071459)3.37393304
84exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.36714153
85termination of RNA polymerase I transcription (GO:0006363)3.35547855
86transcription elongation from RNA polymerase I promoter (GO:0006362)3.33970323
87mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.33592896
88mitochondrial respiratory chain complex I assembly (GO:0032981)3.33592896
89NADH dehydrogenase complex assembly (GO:0010257)3.33592896
90regulation of ubiquitin-protein transferase activity (GO:0051438)3.33268440
91nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.32594228
92mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.32262887
93cellular component biogenesis (GO:0044085)3.32000258
94antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.31577712
95G1/S transition of mitotic cell cycle (GO:0000082)3.31280683
96cell cycle G1/S phase transition (GO:0044843)3.31280683
97DNA damage response, detection of DNA damage (GO:0042769)3.31218839
98IMP biosynthetic process (GO:0006188)3.28674685
99DNA replication-dependent nucleosome assembly (GO:0006335)3.28102489
100DNA replication-dependent nucleosome organization (GO:0034723)3.28102489
101transcription-coupled nucleotide-excision repair (GO:0006283)3.26794668
102protein deneddylation (GO:0000338)3.26475301
103peptidyl-histidine modification (GO:0018202)3.23878853
104nucleobase-containing small molecule interconversion (GO:0015949)3.22983046
105metaphase plate congression (GO:0051310)3.22721584
106DNA replication-independent nucleosome assembly (GO:0006336)3.22554564
107DNA replication-independent nucleosome organization (GO:0034724)3.22554564
108regulation of ligase activity (GO:0051340)3.20860076
109transcription from RNA polymerase I promoter (GO:0006360)3.20343166
110inner mitochondrial membrane organization (GO:0007007)3.19979482
111histone exchange (GO:0043486)3.19639150
112protein complex disassembly (GO:0043241)3.19440708
113maturation of 5.8S rRNA (GO:0000460)3.18462451
114regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.14767936
115mitotic nuclear envelope disassembly (GO:0007077)3.14365501
116rRNA methylation (GO:0031167)3.13348074
117mitotic recombination (GO:0006312)3.12428401
118transcription from mitochondrial promoter (GO:0006390)3.11797913
119cytochrome complex assembly (GO:0017004)3.10528627
120kinetochore organization (GO:0051383)3.07505682
121deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.06257161
122macromolecular complex disassembly (GO:0032984)3.06049255
123tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.05146688
124kinetochore assembly (GO:0051382)3.01770550
125positive regulation of cell cycle arrest (GO:0071158)3.00776778
126spliceosomal complex assembly (GO:0000245)3.00128153
127guanosine-containing compound biosynthetic process (GO:1901070)2.99677774
128ATP synthesis coupled proton transport (GO:0015986)2.99284383
129energy coupled proton transport, down electrochemical gradient (GO:0015985)2.99284383
130regulation of spindle organization (GO:0090224)2.97637196
131attachment of spindle microtubules to kinetochore (GO:0008608)2.97073307

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.83548071
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.38241864
3* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.90258392
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.84089384
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.74937626
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.59568835
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.50266656
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.34153183
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.26161593
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.07942561
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.03737338
12FOXM1_23109430_ChIP-Seq_U2OS_Human3.02327416
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.99867237
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.92741145
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.91341880
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.88718726
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.75126381
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.73216216
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.72020660
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.67909103
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.64744924
22VDR_23849224_ChIP-Seq_CD4+_Human2.56240315
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.54919556
24XRN2_22483619_ChIP-Seq_HELA_Human2.49099911
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38777485
26* DCP1A_22483619_ChIP-Seq_HELA_Human2.30292875
27* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.25036725
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.17764079
29FOXP3_21729870_ChIP-Seq_TREG_Human2.08372563
30* GABP_19822575_ChIP-Seq_HepG2_Human2.04881452
31ELF1_17652178_ChIP-ChIP_JURKAT_Human2.04572520
32TTF2_22483619_ChIP-Seq_HELA_Human1.99869923
33ELK1_19687146_ChIP-ChIP_HELA_Human1.96558040
34AR_21909140_ChIP-Seq_LNCAP_Human1.94075804
35THAP11_20581084_ChIP-Seq_MESCs_Mouse1.88926511
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.86290977
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80528959
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.79491154
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79335028
40SRF_21415370_ChIP-Seq_HL-1_Mouse1.75772902
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.72389619
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.72343644
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.71924358
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.70351848
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65320070
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63594356
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.54625240
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.49566104
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.49342539
50ZFX_18555785_ChIP-Seq_MESCs_Mouse1.47945185
51CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.42110591
52* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39559857
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.36240091
54KDM5A_27292631_Chip-Seq_BREAST_Human1.36079137
55* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.36032578
56TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32542328
57ELK1_22589737_ChIP-Seq_MCF10A_Human1.29984992
58ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26621721
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21407878
60CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.21213622
61CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.20255488
62SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20138277
63BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19257619
64HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.18980346
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.18906270
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18786247
67KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18217642
68CIITA_25753668_ChIP-Seq_RAJI_Human1.15746576
69PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13119003
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12809376
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.11979518
72KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.11385765
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09912731
74SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.07397468
75* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06038358
76E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05659843
77POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05464405
78HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04032148
79MYC_18940864_ChIP-ChIP_HL60_Human1.02661342
80NANOG_16153702_ChIP-ChIP_HESCs_Human1.02157345
81TFEB_21752829_ChIP-Seq_HELA_Human1.02028518
82EGR1_19374776_ChIP-ChIP_THP-1_Human1.01362562
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00990086
84* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.00917439
85* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99599007
86DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99101745
87KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98414273
88ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.98006994
89HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97933545
90CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97199577
91NOTCH1_21737748_ChIP-Seq_TLL_Human0.96993552
92SOX2_16153702_ChIP-ChIP_HESCs_Human0.96097673
93SPI1_23547873_ChIP-Seq_NB4_Human0.93754044
94SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.92797378
95SOX2_18555785_ChIP-Seq_MESCs_Mouse0.86953169
96SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.86497432
97RBPJ_22232070_ChIP-Seq_NCS_Mouse0.83085096
98GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78679728
99POU5F1_16153702_ChIP-ChIP_HESCs_Human0.78327497
100TP63_19390658_ChIP-ChIP_HaCaT_Human0.77203725
101OCT4_18692474_ChIP-Seq_MEFs_Mouse0.76892378
102CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.76619632
103SOX17_20123909_ChIP-Seq_XEN_Mouse0.76479131
104IRF8_21731497_ChIP-ChIP_J774_Mouse0.75453822
105SOX2_18692474_ChIP-Seq_MEFs_Mouse0.75257454
106* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74762402
107PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.72880136
108SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.72799009
109IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.71615861
110CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.71382483
111* EWS_26573619_Chip-Seq_HEK293_Human0.70586431
112MYC_22102868_ChIP-Seq_BL_Human0.70065831
113* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.69978006
114TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.69245150
115* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.69016971

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.04788697
2MP0004957_abnormal_blastocyst_morpholog4.81829561
3MP0003111_abnormal_nucleus_morphology4.29396544
4MP0010094_abnormal_chromosome_stability4.20682227
5MP0003077_abnormal_cell_cycle3.88297117
6MP0008057_abnormal_DNA_replication3.42900289
7MP0008058_abnormal_DNA_repair3.17864693
8MP0008932_abnormal_embryonic_tissue2.80879563
9MP0003718_maternal_effect2.58434842
10MP0008007_abnormal_cellular_replicative2.53625543
11MP0009697_abnormal_copulation2.48593318
12MP0003123_paternal_imprinting2.38184204
13MP0003786_premature_aging2.37810948
14MP0001730_embryonic_growth_arrest2.32213110
15MP0006292_abnormal_olfactory_placode2.25351813
16MP0009333_abnormal_splenocyte_physiolog2.18789398
17MP0003806_abnormal_nucleotide_metabolis2.13432108
18MP0003941_abnormal_skin_development2.00335696
19MP0000350_abnormal_cell_proliferation1.98857812
20MP0003186_abnormal_redox_activity1.87449070
21MP0008877_abnormal_DNA_methylation1.86055394
22MP0002938_white_spotting1.72751837
23MP0005410_abnormal_fertilization1.66519072
24MP0009379_abnormal_foot_pigmentation1.61496071
25MP0002396_abnormal_hematopoietic_system1.60011472
26MP0000490_abnormal_crypts_of1.59181869
27MP0008260_abnormal_autophagy1.58551619
28MP0006036_abnormal_mitochondrial_physio1.53900191
29MP0002210_abnormal_sex_determination1.52895781
30MP0010307_abnormal_tumor_latency1.49727056
31MP0001929_abnormal_gametogenesis1.49661049
32MP0001697_abnormal_embryo_size1.49285156
33MP0000313_abnormal_cell_death1.47309287
34MP0002132_abnormal_respiratory_system1.46581543
35MP0002080_prenatal_lethality1.45534277
36MP0005380_embryogenesis_phenotype1.42239481
37MP0001672_abnormal_embryogenesis/_devel1.42239481
38MP0006035_abnormal_mitochondrial_morpho1.40230422
39MP0000358_abnormal_cell_content/1.36275841
40MP0001764_abnormal_homeostasis1.36220564
41MP0006072_abnormal_retinal_apoptosis1.35384991
42MP0003315_abnormal_perineum_morphology1.34379677
43MP0001145_abnormal_male_reproductive1.31954602
44MP0002019_abnormal_tumor_incidence1.31563100
45MP0005084_abnormal_gallbladder_morpholo1.29911660
46MP0005379_endocrine/exocrine_gland_phen1.26000867
47MP0003221_abnormal_cardiomyocyte_apopto1.25921850
48MP0003984_embryonic_growth_retardation1.25464774
49MP0005397_hematopoietic_system_phenotyp1.25157371
50MP0001545_abnormal_hematopoietic_system1.25157371
51MP0005075_abnormal_melanosome_morpholog1.22508791
52MP0002088_abnormal_embryonic_growth/wei1.20433538
53MP0003567_abnormal_fetal_cardiomyocyte1.19991131
54MP0010352_gastrointestinal_tract_polyps1.14350312
55MP0002837_dystrophic_cardiac_calcinosis1.13524950
56MP0000653_abnormal_sex_gland1.11611466
57MP0002085_abnormal_embryonic_tissue1.10412139
58MP0001727_abnormal_embryo_implantation1.06686240
59MP0001661_extended_life_span1.06499127
60MP0002160_abnormal_reproductive_system1.05767448
61MP0001529_abnormal_vocalization1.03150537
62MP0004808_abnormal_hematopoietic_stem1.01343534
63MP0002398_abnormal_bone_marrow1.00483202
64MP0003698_abnormal_male_reproductive0.99795935
65MP0005501_abnormal_skin_physiology0.99484442
66MP0001835_abnormal_antigen_presentation0.99281826
67MP0002086_abnormal_extraembryonic_tissu0.99075095
68MP0000858_altered_metastatic_potential0.98142073
69MP0009785_altered_susceptibility_to0.97731722
70MP0002722_abnormal_immune_system0.97274233
71MP0002163_abnormal_gland_morphology0.96415586
72MP0003937_abnormal_limbs/digits/tail_de0.94439124
73MP0002102_abnormal_ear_morphology0.94330570
74MP0000689_abnormal_spleen_morphology0.93455652
75MP0000750_abnormal_muscle_regeneration0.92300115
76MP0008995_early_reproductive_senescence0.91811714
77MP0002090_abnormal_vision0.91211782
78MP0005451_abnormal_body_composition0.91089187
79MP0002234_abnormal_pharynx_morphology0.90411751
80MP0002736_abnormal_nociception_after0.89630902
81MP0005389_reproductive_system_phenotype0.89281933
82MP0003656_abnormal_erythrocyte_physiolo0.88701053
83MP0001542_abnormal_bone_strength0.88373109
84MP0009672_abnormal_birth_weight0.88158815
85MP0002084_abnormal_developmental_patter0.87462635
86MP0004197_abnormal_fetal_growth/weight/0.85895434
87MP0002429_abnormal_blood_cell0.85712859
88MP0003763_abnormal_thymus_physiology0.84937414
89MP0005671_abnormal_response_to0.82831913
90MP0005332_abnormal_amino_acid0.81883145
91MP0003136_yellow_coat_color0.81526824
92MP0008789_abnormal_olfactory_epithelium0.81163703
93MP0001853_heart_inflammation0.81109819
94MP0000372_irregular_coat_pigmentation0.80219809
95MP0000703_abnormal_thymus_morphology0.80164851
96MP0002796_impaired_skin_barrier0.79965134
97MP0001881_abnormal_mammary_gland0.78184743
98MP0002751_abnormal_autonomic_nervous0.77513952
99MP0002148_abnormal_hypersensitivity_rea0.77102190
100MP0000716_abnormal_immune_system0.76543408
101MP0005408_hypopigmentation0.76198629
102MP0005367_renal/urinary_system_phenotyp0.74724271
103MP0000516_abnormal_urinary_system0.74724271
104MP0001286_abnormal_eye_development0.74385100
105MP0003890_abnormal_embryonic-extraembry0.74027215
106MP0002111_abnormal_tail_morphology0.73771479
107MP0002697_abnormal_eye_size0.73736226
108MP0001293_anophthalmia0.73460574
109MP0001119_abnormal_female_reproductive0.73428313
110MP0002233_abnormal_nose_morphology0.72951076
111MP0004147_increased_porphyrin_level0.71632124
112MP0002161_abnormal_fertility/fecundity0.71448591
113MP0001919_abnormal_reproductive_system0.70687192
114MP0010030_abnormal_orbit_morphology0.70289897
115MP0005384_cellular_phenotype0.69565822
116MP0003646_muscle_fatigue0.69490868
117MP0002405_respiratory_system_inflammati0.69389998
118MP0003448_altered_tumor_morphology0.68919770
119MP0002653_abnormal_ependyma_morphology0.68623363
120MP0000647_abnormal_sebaceous_gland0.68176303
121MP0001819_abnormal_immune_cell0.67236525
122MP0002420_abnormal_adaptive_immunity0.66601540
123MP0001346_abnormal_lacrimal_gland0.66016191
124MP0002452_abnormal_antigen_presenting0.65961584
125MP0005394_taste/olfaction_phenotype0.64220713
126MP0005499_abnormal_olfactory_system0.64220713
127MP0005395_other_phenotype0.64124174
128MP0001188_hyperpigmentation0.64075939
129MP0003119_abnormal_digestive_system0.64049453
130MP0005330_cardiomyopathy0.63931438
131MP0000049_abnormal_middle_ear0.63614789
132MP0000631_abnormal_neuroendocrine_gland0.62434264
133MP0002277_abnormal_respiratory_mucosa0.61550689
134MP0005000_abnormal_immune_tolerance0.61446147
135MP0002723_abnormal_immune_serum0.61098708
136MP0003011_delayed_dark_adaptation0.60685292
137MP0005266_abnormal_metabolism0.60442627
138MP0000537_abnormal_urethra_morphology0.60207775
139MP0002095_abnormal_skin_pigmentation0.59919983
140MP0005025_abnormal_response_to0.59496300
141MP0001905_abnormal_dopamine_level0.58262488
142MP0006054_spinal_hemorrhage0.58175036
143MP0001800_abnormal_humoral_immune0.57790713

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.65830769
2Abnormal number of erythroid precursors (HP:0012131)5.18703381
3Birth length less than 3rd percentile (HP:0003561)4.75885001
4Reticulocytopenia (HP:0001896)4.34991506
5Breast hypoplasia (HP:0003187)4.20679502
6Oral leukoplakia (HP:0002745)4.00956829
7Acute necrotizing encephalopathy (HP:0006965)3.71771593
8Macrocytic anemia (HP:0001972)3.68286502
9Rough bone trabeculation (HP:0100670)3.67473450
10Cerebral hypomyelination (HP:0006808)3.64056014
11Renal Fanconi syndrome (HP:0001994)3.63810508
12Multiple enchondromatosis (HP:0005701)3.51805840
13Abnormality of the anterior horn cell (HP:0006802)3.47135820
14Degeneration of anterior horn cells (HP:0002398)3.47135820
15Carpal bone hypoplasia (HP:0001498)3.35088681
16Microvesicular hepatic steatosis (HP:0001414)3.32573278
17Abnormal mitochondria in muscle tissue (HP:0008316)3.28726216
18Mitochondrial inheritance (HP:0001427)3.23675294
19Pallor (HP:0000980)3.23400681
20Increased intramyocellular lipid droplets (HP:0012240)3.22989948
21Increased CSF lactate (HP:0002490)3.13033695
22Increased serum pyruvate (HP:0003542)3.13020075
23Abnormality of glycolysis (HP:0004366)3.13020075
24Aplastic anemia (HP:0001915)3.12851046
25Microretrognathia (HP:0000308)2.99707408
26Decreased activity of mitochondrial respiratory chain (HP:0008972)2.91952998
27Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.91952998
28Type I transferrin isoform profile (HP:0003642)2.88344108
29Patellar aplasia (HP:0006443)2.87733724
30Trismus (HP:0000211)2.86230503
31Progressive macrocephaly (HP:0004481)2.84027898
32Leukodystrophy (HP:0002415)2.83147275
33Hepatocellular necrosis (HP:0001404)2.82490318
34Acute encephalopathy (HP:0006846)2.82338954
35Increased hepatocellular lipid droplets (HP:0006565)2.79726974
36Abnormal trabecular bone morphology (HP:0100671)2.77514992
37Impulsivity (HP:0100710)2.77375786
38Aplasia/Hypoplasia of the patella (HP:0006498)2.75047938
39Increased serum lactate (HP:0002151)2.71853520
40Increased muscle lipid content (HP:0009058)2.59724655
41Abnormality of the preputium (HP:0100587)2.58124796
42Absent thumb (HP:0009777)2.54535307
43Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.54394068
44Abnormality of methionine metabolism (HP:0010901)2.50640271
45Secondary amenorrhea (HP:0000869)2.49412188
46Premature graying of hair (HP:0002216)2.47550585
47Abnormality of the umbilical cord (HP:0010881)2.45399944
48Exertional dyspnea (HP:0002875)2.45197045
49Cleft eyelid (HP:0000625)2.44419183
50Hepatic necrosis (HP:0002605)2.43089797
51Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.43065926
52Hypoplasia of the capital femoral epiphysis (HP:0003090)2.42019404
53Colon cancer (HP:0003003)2.40730039
54Selective tooth agenesis (HP:0001592)2.40673181
55Lipid accumulation in hepatocytes (HP:0006561)2.40015324
56Premature ovarian failure (HP:0008209)2.38910751
57Meckel diverticulum (HP:0002245)2.38367635
58Respiratory difficulties (HP:0002880)2.37711300
59Abnormal protein glycosylation (HP:0012346)2.37589817
60Abnormal glycosylation (HP:0012345)2.37589817
61Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.37589817
62Abnormal protein N-linked glycosylation (HP:0012347)2.37589817
63Sparse eyelashes (HP:0000653)2.36057165
64Abnormal spermatogenesis (HP:0008669)2.35042385
65Lethargy (HP:0001254)2.33683557
66Reduced antithrombin III activity (HP:0001976)2.31535228
67Horseshoe kidney (HP:0000085)2.31411089
68Optic disc pallor (HP:0000543)2.30728867
69Absent radius (HP:0003974)2.26137224
70Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.25389943
71Abnormality of the labia minora (HP:0012880)2.24449228
72Abnormality of the ileum (HP:0001549)2.23656301
733-Methylglutaconic aciduria (HP:0003535)2.23600991
74Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.21780868
75Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.19982067
76Abnormality of alanine metabolism (HP:0010916)2.19982067
77Hyperalaninemia (HP:0003348)2.19982067
78Glossoptosis (HP:0000162)2.19887466
79Abnormality of serum amino acid levels (HP:0003112)2.18474013
80Chromsome breakage (HP:0040012)2.17387345
81Chromosomal breakage induced by crosslinking agents (HP:0003221)2.16950364
82Exercise intolerance (HP:0003546)2.15406004
83Ureteral duplication (HP:0000073)2.14481820
84Cellular immunodeficiency (HP:0005374)2.14261392
85Hyperglycinemia (HP:0002154)2.13711891
86Bone marrow hypocellularity (HP:0005528)2.12637343
87Aplasia/Hypoplasia of the sacrum (HP:0008517)2.12532093
88Respiratory failure (HP:0002878)2.12467522
89Abnormality of placental membranes (HP:0011409)2.12345160
90Amniotic constriction ring (HP:0009775)2.12345160
91Postnatal microcephaly (HP:0005484)2.10192686
92Absent forearm bone (HP:0003953)2.09101337
93Aplasia involving forearm bones (HP:0009822)2.09101337
94CNS hypomyelination (HP:0003429)2.08931694
95Sensory axonal neuropathy (HP:0003390)2.08663785
96Hypoglycemic coma (HP:0001325)2.08222360
97Neoplasm of the pancreas (HP:0002894)2.06964556
98Lactic acidosis (HP:0003128)2.02297970
99Muscle fiber atrophy (HP:0100295)2.02203026
100Progressive muscle weakness (HP:0003323)2.02136402
101Pancytopenia (HP:0001876)2.01197677
102Abnormality of aspartate family amino acid metabolism (HP:0010899)1.99818599
103Irregular epiphyses (HP:0010582)1.98810228
104Abnormality of chromosome stability (HP:0003220)1.97744029
105CNS demyelination (HP:0007305)1.97689692
106Abnormality of renal resorption (HP:0011038)1.96337250
107Triphalangeal thumb (HP:0001199)1.94216868
108Small intestinal stenosis (HP:0012848)1.93554987
109Duodenal stenosis (HP:0100867)1.93554987
110Methylmalonic aciduria (HP:0012120)1.91919674
111Generalized aminoaciduria (HP:0002909)1.91822447
112Agnosia (HP:0010524)1.91733070
113Glycosuria (HP:0003076)1.91595375
114Abnormality of urine glucose concentration (HP:0011016)1.91595375
115Neoplasm of the adrenal gland (HP:0100631)1.91415563
116Atrophy/Degeneration involving motor neurons (HP:0007373)1.90890738
117Type 2 muscle fiber atrophy (HP:0003554)1.90526791
118Abnormal umbilical cord blood vessels (HP:0011403)1.90391504
119Single umbilical artery (HP:0001195)1.90391504
120Abnormality of the fetal cardiovascular system (HP:0010948)1.90391504
121Methylmalonic acidemia (HP:0002912)1.89783422
122Congenital, generalized hypertrichosis (HP:0004540)1.88419483
123Personality changes (HP:0000751)1.87868980
124Absent epiphyses (HP:0010577)1.87763766
125Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.87763766
126Aplasia/Hypoplasia of the uvula (HP:0010293)1.87306976
127Cerebral edema (HP:0002181)1.87274914
128Death in infancy (HP:0001522)1.86129637
129Hypoplasia of the radius (HP:0002984)1.85340866
130Megaloblastic anemia (HP:0001889)1.84931987
131Testicular atrophy (HP:0000029)1.81654675
132Abnormal lung lobation (HP:0002101)1.80721151
133Facial cleft (HP:0002006)1.80569588
134X-linked dominant inheritance (HP:0001423)1.77097483
135Hyperinsulinemic hypoglycemia (HP:0000825)1.75015321
136Hyperphosphaturia (HP:0003109)1.73480021
137Ependymoma (HP:0002888)1.69038064
138Myelodysplasia (HP:0002863)1.68748310
139Emotional lability (HP:0000712)1.67765469

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.02191529
2NME24.44893937
3VRK24.32550630
4WEE14.24557356
5EIF2AK13.42174037
6CDC72.92675768
7NEK22.60277292
8SRPK12.58011604
9TESK22.38265702
10STK162.37622455
11EIF2AK32.30891990
12BRSK22.27864758
13TESK12.12839900
14PBK2.07108115
15ACVR1B2.04431688
16PLK42.03106097
17NEK12.01909422
18DYRK32.00811677
19TAF11.94453374
20VRK11.87844305
21RPS6KA41.82242747
22PIM21.79902421
23PLK11.79133590
24PDK41.73122699
25PDK31.73122699
26TRIM281.68601034
27NUAK11.65054808
28TTK1.55166328
29TSSK61.50394900
30CDK191.49691048
31AURKB1.46725165
32TLK11.45181059
33BRAF1.44598188
34PLK31.36209234
35MST41.34538872
36CCNB11.33242654
37LIMK11.28778400
38BRSK11.26699318
39AURKA1.24909242
40MKNK11.20459050
41ARAF1.19751078
42PDK21.14427239
43CDK71.13339328
44ZAK1.11886677
45MAP3K81.06073691
46CHEK21.05525320
47NME11.01577889
48KDR1.01251247
49ATR0.98671144
50EPHA20.97361506
51MAP3K110.92246357
52STK40.90241334
53EIF2AK20.89709998
54MAP4K20.89659072
55PAK10.86283043
56PAK40.85601478
57RPS6KB20.83551640
58PASK0.83438693
59DAPK10.81372976
60CDK40.81064541
61BMPR1B0.79622645
62WNK30.78411333
63CHEK10.75548877
64PIM10.74710702
65MKNK20.74606799
66ERBB30.73636295
67CSNK2A10.72244289
68STK100.70066456
69DYRK20.69947610
70CSNK2A20.67591533
71LRRK20.66054735
72CSNK1A1L0.66047422
73MARK30.64893041
74ABL20.64511699
75ALK0.62950199
76SMG10.62681499
77RPS6KA50.60971498
78MAP2K70.60557403
79CSNK1G20.60406316
80DAPK30.59799293
81PNCK0.59038457
82ILK0.58874538
83MAP2K20.57974756
84CSNK1G30.57040175
85PRKCI0.53870459
86STK30.49279258
87TAOK20.49051802
88SCYL20.47099908
89AKT20.44228201
90CDK20.42918594
91CDK80.42120777
92OXSR10.41755033
93PLK20.41505454
94BLK0.40640236
95CSNK1E0.40539643
96TGFBR10.38440981
97STK38L0.38062865
98ATM0.37400259
99ERBB40.36099473
100BCR0.36086385
101MAP3K50.35758426
102GRK10.34255390
103CSNK1G10.32869672
104BCKDK0.31803116
105TIE10.31376432
106INSRR0.31167033
107IKBKB0.30047790
108CDK10.29848671
109YES10.29617716
110ZAP700.28812997
111MAPKAPK50.26717732
112IRAK40.25341430
113CDK140.24704701
114TYK20.24642602
115NLK0.24636611
116RAF10.24179408
117STK240.24077779
118MAP3K30.23833087
119CDK30.22900337
120MAP2K30.22539080
121IRAK20.22080483
122MAP3K120.21744701
123MAP4K10.19128346
124MELK0.19042827
125GRK60.19038293
126CDK11A0.18095452
127LATS20.17953403

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.91329637
2Ribosome_Homo sapiens_hsa030104.49625243
3DNA replication_Homo sapiens_hsa030303.96520185
4RNA polymerase_Homo sapiens_hsa030203.87135902
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.65696494
6Mismatch repair_Homo sapiens_hsa034303.21266919
7Spliceosome_Homo sapiens_hsa030402.97129241
8RNA transport_Homo sapiens_hsa030132.90172480
9Pyrimidine metabolism_Homo sapiens_hsa002402.69331458
10Nucleotide excision repair_Homo sapiens_hsa034202.53910554
11Homologous recombination_Homo sapiens_hsa034402.38617467
12Base excision repair_Homo sapiens_hsa034102.36975863
13Oxidative phosphorylation_Homo sapiens_hsa001902.17062842
14Cell cycle_Homo sapiens_hsa041102.15939193
15Basal transcription factors_Homo sapiens_hsa030222.05456622
16Parkinsons disease_Homo sapiens_hsa050121.99444163
17Vitamin B6 metabolism_Homo sapiens_hsa007501.96361730
18Huntingtons disease_Homo sapiens_hsa050161.80571656
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.72307786
20Fanconi anemia pathway_Homo sapiens_hsa034601.66320612
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.62990087
22RNA degradation_Homo sapiens_hsa030181.61433150
23One carbon pool by folate_Homo sapiens_hsa006701.57593882
24Purine metabolism_Homo sapiens_hsa002301.52780519
25p53 signaling pathway_Homo sapiens_hsa041151.44057214
26Protein export_Homo sapiens_hsa030601.39166925
27Fatty acid elongation_Homo sapiens_hsa000621.35941480
28Epstein-Barr virus infection_Homo sapiens_hsa051691.25989661
29mRNA surveillance pathway_Homo sapiens_hsa030151.16537226
30Pentose phosphate pathway_Homo sapiens_hsa000301.15617168
31Alzheimers disease_Homo sapiens_hsa050101.15094660
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.11845980
33Sulfur relay system_Homo sapiens_hsa041221.10491958
34Non-homologous end-joining_Homo sapiens_hsa034501.08938865
35Propanoate metabolism_Homo sapiens_hsa006401.06560361
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.04075987
37Sulfur metabolism_Homo sapiens_hsa009201.03513153
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.03263578
39Systemic lupus erythematosus_Homo sapiens_hsa053220.96949025
40Folate biosynthesis_Homo sapiens_hsa007900.96561224
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93982256
42Glutathione metabolism_Homo sapiens_hsa004800.89929061
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87038698
44Cysteine and methionine metabolism_Homo sapiens_hsa002700.84990271
45Steroid biosynthesis_Homo sapiens_hsa001000.84220967
46Oocyte meiosis_Homo sapiens_hsa041140.82168807
47Antigen processing and presentation_Homo sapiens_hsa046120.80374176
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.79765663
49Legionellosis_Homo sapiens_hsa051340.74412818
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73291556
51Regulation of autophagy_Homo sapiens_hsa041400.72657919
52Herpes simplex infection_Homo sapiens_hsa051680.72208847
53Biosynthesis of amino acids_Homo sapiens_hsa012300.71750781
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.71072777
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70637409
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69358148
57Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.67395575
58Viral carcinogenesis_Homo sapiens_hsa052030.65522613
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.65430461
60Carbon metabolism_Homo sapiens_hsa012000.64086034
61Peroxisome_Homo sapiens_hsa041460.56996312
62Selenocompound metabolism_Homo sapiens_hsa004500.53020160
63Cardiac muscle contraction_Homo sapiens_hsa042600.51544892
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50122262
65Metabolic pathways_Homo sapiens_hsa011000.49663763
66Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49018922
67Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47372620
68Graft-versus-host disease_Homo sapiens_hsa053320.46660303
692-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44000344
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43749642
71Allograft rejection_Homo sapiens_hsa053300.43362871
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43044218
73Cyanoamino acid metabolism_Homo sapiens_hsa004600.42566184
74Butanoate metabolism_Homo sapiens_hsa006500.40390436
75Asthma_Homo sapiens_hsa053100.39520440
76Primary immunodeficiency_Homo sapiens_hsa053400.39294310
77Fructose and mannose metabolism_Homo sapiens_hsa000510.39095202
78Arachidonic acid metabolism_Homo sapiens_hsa005900.38440710
79HTLV-I infection_Homo sapiens_hsa051660.38368502
80Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38150864
81Apoptosis_Homo sapiens_hsa042100.36877226
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36408050
83Shigellosis_Homo sapiens_hsa051310.33712276
84Intestinal immune network for IgA production_Homo sapiens_hsa046720.33518680
85Fatty acid metabolism_Homo sapiens_hsa012120.33485149
86Tryptophan metabolism_Homo sapiens_hsa003800.30367477
87Autoimmune thyroid disease_Homo sapiens_hsa053200.30068811
88Thyroid cancer_Homo sapiens_hsa052160.29399675
89Fatty acid degradation_Homo sapiens_hsa000710.29298845
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28875599
91Galactose metabolism_Homo sapiens_hsa000520.28440329
92beta-Alanine metabolism_Homo sapiens_hsa004100.28105684
93Vibrio cholerae infection_Homo sapiens_hsa051100.26778099
94Measles_Homo sapiens_hsa051620.26688767
95Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26656557
96Primary bile acid biosynthesis_Homo sapiens_hsa001200.26429329
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25731600
98Linoleic acid metabolism_Homo sapiens_hsa005910.24501640
99Tyrosine metabolism_Homo sapiens_hsa003500.24119227
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.23323656
101Vitamin digestion and absorption_Homo sapiens_hsa049770.22742362
102Pyruvate metabolism_Homo sapiens_hsa006200.22592213
103NF-kappa B signaling pathway_Homo sapiens_hsa040640.20218769
104Maturity onset diabetes of the young_Homo sapiens_hsa049500.19604251
105Collecting duct acid secretion_Homo sapiens_hsa049660.19012223
106Rheumatoid arthritis_Homo sapiens_hsa053230.18672195
107Alcoholism_Homo sapiens_hsa050340.18589062
108Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18438006
109Small cell lung cancer_Homo sapiens_hsa052220.17264089
110Influenza A_Homo sapiens_hsa051640.16324517
111Hematopoietic cell lineage_Homo sapiens_hsa046400.16201259
112Hepatitis B_Homo sapiens_hsa051610.15874669
113Phagosome_Homo sapiens_hsa041450.15740346
114Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.14793767
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.14203203
116N-Glycan biosynthesis_Homo sapiens_hsa005100.14200008
117Viral myocarditis_Homo sapiens_hsa054160.12511528
118Phenylalanine metabolism_Homo sapiens_hsa003600.12009306
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.11910920
120Arginine biosynthesis_Homo sapiens_hsa002200.11113390
121Arginine and proline metabolism_Homo sapiens_hsa003300.09425021
122Renin-angiotensin system_Homo sapiens_hsa046140.09008195
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.08389530
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.08033907
125Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.07846005
126HIF-1 signaling pathway_Homo sapiens_hsa040660.07707776
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.06940834
128Fat digestion and absorption_Homo sapiens_hsa049750.06394196
129Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.04621964
130Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.03641087
131Chemical carcinogenesis_Homo sapiens_hsa052040.02984526

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