

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of 5.8S rRNA (GO:0000460) | 6.20087167 |
| 2 | proteasome assembly (GO:0043248) | 5.07266686 |
| 3 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.89575397 |
| 4 | regulation of mitochondrial translation (GO:0070129) | 4.66151742 |
| 5 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.46910082 |
| 6 | nucleotide transmembrane transport (GO:1901679) | 4.42999522 |
| 7 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 4.31248246 |
| 8 | spliceosomal snRNP assembly (GO:0000387) | 4.29609258 |
| 9 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.11606240 |
| 10 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.09465421 |
| 11 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.09465421 |
| 12 | positive regulation of mitochondrial fission (GO:0090141) | 4.06180346 |
| 13 | pseudouridine synthesis (GO:0001522) | 4.04670376 |
| 14 | protein-cofactor linkage (GO:0018065) | 4.01194853 |
| 15 | pyrimidine dimer repair (GO:0006290) | 3.97522420 |
| 16 | iron-sulfur cluster assembly (GO:0016226) | 3.67201966 |
| 17 | metallo-sulfur cluster assembly (GO:0031163) | 3.67201966 |
| 18 | DNA double-strand break processing (GO:0000729) | 3.58989044 |
| 19 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.52376401 |
| 20 | protein import into peroxisome matrix (GO:0016558) | 3.50976273 |
| 21 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.50917443 |
| 22 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.47675363 |
| 23 | peptidyl-histidine modification (GO:0018202) | 3.46002963 |
| 24 | ribosome assembly (GO:0042255) | 3.44408449 |
| 25 | 7-methylguanosine RNA capping (GO:0009452) | 3.39919053 |
| 26 | RNA capping (GO:0036260) | 3.39919053 |
| 27 | mitochondrial RNA metabolic process (GO:0000959) | 3.38223640 |
| 28 | rRNA modification (GO:0000154) | 3.30033591 |
| 29 | protein localization to peroxisome (GO:0072662) | 3.29465358 |
| 30 | protein targeting to peroxisome (GO:0006625) | 3.29465358 |
| 31 | establishment of protein localization to peroxisome (GO:0072663) | 3.29465358 |
| 32 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.28773787 |
| 33 | DNA integration (GO:0015074) | 3.27066042 |
| 34 | chaperone-mediated protein transport (GO:0072321) | 3.26125126 |
| 35 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.25947763 |
| 36 | replication fork processing (GO:0031297) | 3.22286735 |
| 37 | intracellular protein transmembrane import (GO:0044743) | 3.22098067 |
| 38 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.21130943 |
| 39 | histone mRNA metabolic process (GO:0008334) | 3.18738529 |
| 40 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.18111842 |
| 41 | protein targeting to mitochondrion (GO:0006626) | 3.16770977 |
| 42 | RNA methylation (GO:0001510) | 3.16758698 |
| 43 | protein localization to mitochondrion (GO:0070585) | 3.12601890 |
| 44 | establishment of integrated proviral latency (GO:0075713) | 3.11333948 |
| 45 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.08635978 |
| 46 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.07780592 |
| 47 | peroxisomal transport (GO:0043574) | 3.07756250 |
| 48 | platelet dense granule organization (GO:0060155) | 3.07515766 |
| 49 | ubiquinone biosynthetic process (GO:0006744) | 3.06664647 |
| 50 | * tRNA processing (GO:0008033) | 3.06297456 |
| 51 | DNA deamination (GO:0045006) | 3.06241303 |
| 52 | establishment of viral latency (GO:0019043) | 3.03648194 |
| 53 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.00381318 |
| 54 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.00150576 |
| 55 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.00150576 |
| 56 | NADH dehydrogenase complex assembly (GO:0010257) | 3.00150576 |
| 57 | rRNA methylation (GO:0031167) | 2.98210637 |
| 58 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.96516335 |
| 59 | protein complex biogenesis (GO:0070271) | 2.95864917 |
| 60 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.94489688 |
| 61 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.90033650 |
| 62 | negative regulation of ligase activity (GO:0051352) | 2.89581623 |
| 63 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.89581623 |
| 64 | * tRNA metabolic process (GO:0006399) | 2.88614130 |
| 65 | deoxyribonucleotide catabolic process (GO:0009264) | 2.87271549 |
| 66 | termination of RNA polymerase II transcription (GO:0006369) | 2.85569974 |
| 67 | peptidyl-arginine N-methylation (GO:0035246) | 2.84935918 |
| 68 | peptidyl-arginine methylation (GO:0018216) | 2.84935918 |
| 69 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.84356946 |
| 70 | base-excision repair, AP site formation (GO:0006285) | 2.83963943 |
| 71 | establishment of protein localization to mitochondrion (GO:0072655) | 2.83466088 |
| 72 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.83029870 |
| 73 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.83029870 |
| 74 | tRNA modification (GO:0006400) | 2.82780351 |
| 75 | deoxyribose phosphate catabolic process (GO:0046386) | 2.81553268 |
| 76 | ubiquinone metabolic process (GO:0006743) | 2.81162326 |
| 77 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.80945162 |
| 78 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.80945162 |
| 79 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.80874430 |
| 80 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.80874430 |
| 81 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.80874430 |
| 82 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.80393962 |
| 83 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.79907071 |
| 84 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.79907071 |
| 85 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.79189222 |
| 86 | protein deneddylation (GO:0000338) | 2.79159672 |
| 87 | deoxyribose phosphate metabolic process (GO:0019692) | 2.77226943 |
| 88 | amino acid salvage (GO:0043102) | 2.75406025 |
| 89 | L-methionine salvage (GO:0071267) | 2.75406025 |
| 90 | L-methionine biosynthetic process (GO:0071265) | 2.75406025 |
| 91 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.74325984 |
| 92 | cullin deneddylation (GO:0010388) | 2.73789039 |
| 93 | histone arginine methylation (GO:0034969) | 2.73640914 |
| 94 | regulation of helicase activity (GO:0051095) | 2.73412027 |
| 95 | chromatin remodeling at centromere (GO:0031055) | 2.72547214 |
| 96 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.72439494 |
| 97 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.72439494 |
| 98 | deoxyribonucleotide metabolic process (GO:0009262) | 2.72197049 |
| 99 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.71778225 |
| 100 | non-recombinational repair (GO:0000726) | 2.71778225 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.62560606 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.38528107 |
| 3 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.77994304 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.76420223 |
| 5 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.56275883 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.42865837 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.40321753 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.39323731 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.23865934 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.13151929 |
| 11 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.04694913 |
| 12 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.03372206 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.01645079 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.94911156 |
| 15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.89195267 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.85028989 |
| 17 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.72671780 |
| 18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.65560899 |
| 19 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 2.63996519 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.63863191 |
| 21 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.63644559 |
| 22 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.58299274 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.58098212 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.52572139 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.39046386 |
| 26 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.34463096 |
| 27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.31558691 |
| 28 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.30561323 |
| 29 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.30147724 |
| 30 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.25726523 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.20365232 |
| 32 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.17463610 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.16442133 |
| 34 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.13728658 |
| 35 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.11268307 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.10263268 |
| 37 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.08967003 |
| 38 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 2.06398352 |
| 39 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.99115041 |
| 40 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.98571546 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.97701266 |
| 42 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.91965854 |
| 43 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.91589887 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.79658265 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.76959972 |
| 46 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.76643557 |
| 47 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.62712237 |
| 48 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.60742590 |
| 49 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.59754103 |
| 50 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.58236082 |
| 51 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.53017924 |
| 52 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.52697160 |
| 53 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.51008360 |
| 54 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49405293 |
| 55 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.49205557 |
| 56 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.48630617 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.47225924 |
| 58 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.42027727 |
| 59 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.42007854 |
| 60 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.38003147 |
| 61 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.34742660 |
| 62 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34502641 |
| 63 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.32294300 |
| 64 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.30494424 |
| 65 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.30443648 |
| 66 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.30253086 |
| 67 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.27706255 |
| 68 | * ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.25447530 |
| 69 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24303751 |
| 70 | EWS_26573619_Chip-Seq_HEK293_Human | 1.22864183 |
| 71 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.18009349 |
| 72 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14300145 |
| 73 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.13491243 |
| 74 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.07527005 |
| 75 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.07475617 |
| 76 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.05778517 |
| 77 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01997754 |
| 78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00057579 |
| 79 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.99355159 |
| 80 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.96624744 |
| 81 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.94750267 |
| 82 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.93488807 |
| 83 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.92484909 |
| 84 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.92203930 |
| 85 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91608965 |
| 86 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.87483561 |
| 87 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.85619848 |
| 88 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.85003703 |
| 89 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.84883731 |
| 90 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84124393 |
| 91 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.84086143 |
| 92 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.83052654 |
| 93 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.82701392 |
| 94 | FUS_26573619_Chip-Seq_HEK293_Human | 0.81970018 |
| 95 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.80289934 |
| 96 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.78585713 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.78471519 |
| 98 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.76821659 |
| 99 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.73009880 |
| 100 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.72833419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 3.61888899 |
| 2 | MP0008058_abnormal_DNA_repair | 3.45675231 |
| 3 | MP0006082_CNS_inflammation | 3.37022011 |
| 4 | MP0008789_abnormal_olfactory_epithelium | 3.31718897 |
| 5 | MP0003693_abnormal_embryo_hatching | 3.22668072 |
| 6 | MP0008057_abnormal_DNA_replication | 2.69016358 |
| 7 | MP0002132_abnormal_respiratory_system | 2.66440769 |
| 8 | MP0003111_abnormal_nucleus_morphology | 2.58994395 |
| 9 | MP0001529_abnormal_vocalization | 2.58958055 |
| 10 | MP0002102_abnormal_ear_morphology | 2.48918836 |
| 11 | MP0005499_abnormal_olfactory_system | 2.47173726 |
| 12 | MP0005394_taste/olfaction_phenotype | 2.47173726 |
| 13 | MP0006292_abnormal_olfactory_placode | 2.38986871 |
| 14 | MP0003077_abnormal_cell_cycle | 2.36775632 |
| 15 | MP0005367_renal/urinary_system_phenotyp | 2.35886342 |
| 16 | MP0000516_abnormal_urinary_system | 2.35886342 |
| 17 | MP0002254_reproductive_system_inflammat | 2.26816004 |
| 18 | MP0003315_abnormal_perineum_morphology | 2.13740976 |
| 19 | MP0003786_premature_aging | 2.12606147 |
| 20 | MP0006035_abnormal_mitochondrial_morpho | 2.01324022 |
| 21 | MP0008932_abnormal_embryonic_tissue | 1.96422531 |
| 22 | MP0003186_abnormal_redox_activity | 1.80849609 |
| 23 | MP0004957_abnormal_blastocyst_morpholog | 1.73320930 |
| 24 | MP0003718_maternal_effect | 1.72274871 |
| 25 | MP0009697_abnormal_copulation | 1.66655570 |
| 26 | MP0006036_abnormal_mitochondrial_physio | 1.60031277 |
| 27 | MP0006276_abnormal_autonomic_nervous | 1.58655015 |
| 28 | MP0000372_irregular_coat_pigmentation | 1.56078906 |
| 29 | MP0003221_abnormal_cardiomyocyte_apopto | 1.54977753 |
| 30 | MP0001346_abnormal_lacrimal_gland | 1.54293997 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.53842016 |
| 32 | MP0002095_abnormal_skin_pigmentation | 1.49786688 |
| 33 | MP0002160_abnormal_reproductive_system | 1.49395761 |
| 34 | MP0009384_cardiac_valve_regurgitation | 1.41061447 |
| 35 | MP0000358_abnormal_cell_content/ | 1.40166209 |
| 36 | MP0000049_abnormal_middle_ear | 1.39701087 |
| 37 | MP0002736_abnormal_nociception_after | 1.38231975 |
| 38 | MP0002234_abnormal_pharynx_morphology | 1.33746408 |
| 39 | MP0001727_abnormal_embryo_implantation | 1.31730197 |
| 40 | MP0003806_abnormal_nucleotide_metabolis | 1.31157866 |
| 41 | MP0001293_anophthalmia | 1.28135103 |
| 42 | MP0008007_abnormal_cellular_replicative | 1.26814569 |
| 43 | MP0000613_abnormal_salivary_gland | 1.26679665 |
| 44 | MP0003121_genomic_imprinting | 1.24706399 |
| 45 | MP0005647_abnormal_sex_gland | 1.24663393 |
| 46 | MP0001764_abnormal_homeostasis | 1.18352521 |
| 47 | MP0000647_abnormal_sebaceous_gland | 1.16875520 |
| 48 | MP0002638_abnormal_pupillary_reflex | 1.15499948 |
| 49 | MP0005389_reproductive_system_phenotype | 1.13468656 |
| 50 | MP0000631_abnormal_neuroendocrine_gland | 1.10042459 |
| 51 | MP0001119_abnormal_female_reproductive | 1.09839284 |
| 52 | MP0001919_abnormal_reproductive_system | 1.09254774 |
| 53 | MP0005253_abnormal_eye_physiology | 1.08181091 |
| 54 | MP0001873_stomach_inflammation | 1.07021587 |
| 55 | MP0005187_abnormal_penis_morphology | 1.06656862 |
| 56 | MP0005248_abnormal_Harderian_gland | 1.02807844 |
| 57 | MP0002396_abnormal_hematopoietic_system | 1.00523801 |
| 58 | MP0002822_catalepsy | 0.99532888 |
| 59 | MP0000639_abnormal_adrenal_gland | 0.99027711 |
| 60 | MP0009333_abnormal_splenocyte_physiolog | 0.97961368 |
| 61 | MP0002837_dystrophic_cardiac_calcinosis | 0.97909867 |
| 62 | MP0005220_abnormal_exocrine_pancreas | 0.96679992 |
| 63 | MP0002751_abnormal_autonomic_nervous | 0.96573138 |
| 64 | MP0001545_abnormal_hematopoietic_system | 0.95847246 |
| 65 | MP0005397_hematopoietic_system_phenotyp | 0.95847246 |
| 66 | MP0002938_white_spotting | 0.95558693 |
| 67 | MP0004133_heterotaxia | 0.95414830 |
| 68 | MP0000313_abnormal_cell_death | 0.95167231 |
| 69 | MP0000465_gastrointestinal_hemorrhage | 0.94735109 |
| 70 | MP0000653_abnormal_sex_gland | 0.93166237 |
| 71 | MP0004147_increased_porphyrin_level | 0.92823812 |
| 72 | MP0002019_abnormal_tumor_incidence | 0.92068510 |
| 73 | MP0002233_abnormal_nose_morphology | 0.91224525 |
| 74 | MP0001984_abnormal_olfaction | 0.91219084 |
| 75 | MP0002277_abnormal_respiratory_mucosa | 0.89018166 |
| 76 | MP0003183_abnormal_peptide_metabolism | 0.88022050 |
| 77 | MP0002210_abnormal_sex_determination | 0.87736927 |
| 78 | MP0001929_abnormal_gametogenesis | 0.86848320 |
| 79 | MP0002282_abnormal_trachea_morphology | 0.85242608 |
| 80 | MP0008995_early_reproductive_senescence | 0.84803869 |
| 81 | MP0001145_abnormal_male_reproductive | 0.83130394 |
| 82 | MP0002177_abnormal_outer_ear | 0.82251456 |
| 83 | MP0000015_abnormal_ear_pigmentation | 0.82227140 |
| 84 | MP0008260_abnormal_autophagy | 0.81473580 |
| 85 | MP0005310_abnormal_salivary_gland | 0.80791890 |
| 86 | MP0000750_abnormal_muscle_regeneration | 0.80677660 |
| 87 | MP0005266_abnormal_metabolism | 0.80548579 |
| 88 | MP0005075_abnormal_melanosome_morpholog | 0.80430495 |
| 89 | MP0003385_abnormal_body_wall | 0.78923815 |
| 90 | MP0000350_abnormal_cell_proliferation | 0.76485476 |
| 91 | MP0005391_vision/eye_phenotype | 0.74944027 |
| 92 | MP0001905_abnormal_dopamine_level | 0.73899862 |
| 93 | MP0009046_muscle_twitch | 0.71859306 |
| 94 | MP0003698_abnormal_male_reproductive | 0.70701535 |
| 95 | MP0003937_abnormal_limbs/digits/tail_de | 0.70626886 |
| 96 | MP0001270_distended_abdomen | 0.70483996 |
| 97 | MP0002080_prenatal_lethality | 0.70314948 |
| 98 | MP0000371_diluted_coat_color | 0.67421199 |
| 99 | MP0001697_abnormal_embryo_size | 0.65944090 |
| 100 | MP0009765_abnormal_xenobiotic_induced | 0.65236747 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.76440424 |
| 2 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.76440424 |
| 3 | Abnormal protein glycosylation (HP:0012346) | 3.76440424 |
| 4 | Abnormal glycosylation (HP:0012345) | 3.76440424 |
| 5 | Brushfield spots (HP:0001088) | 3.64571598 |
| 6 | Type I transferrin isoform profile (HP:0003642) | 3.40486337 |
| 7 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.34147757 |
| 8 | Abnormality of alanine metabolism (HP:0010916) | 3.34147757 |
| 9 | Hyperalaninemia (HP:0003348) | 3.34147757 |
| 10 | Abnormality of B cell number (HP:0010975) | 3.22688958 |
| 11 | Aplastic anemia (HP:0001915) | 3.20475344 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.09695549 |
| 13 | Increased CSF lactate (HP:0002490) | 2.98595989 |
| 14 | Increased serum lactate (HP:0002151) | 2.94718284 |
| 15 | Microvesicular hepatic steatosis (HP:0001414) | 2.93683832 |
| 16 | Acute necrotizing encephalopathy (HP:0006965) | 2.93065063 |
| 17 | Medial flaring of the eyebrow (HP:0010747) | 2.88096163 |
| 18 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.87172891 |
| 19 | Hyperglycinemia (HP:0002154) | 2.84361895 |
| 20 | Reduced antithrombin III activity (HP:0001976) | 2.84104818 |
| 21 | Acute encephalopathy (HP:0006846) | 2.80284357 |
| 22 | Mitochondrial inheritance (HP:0001427) | 2.78593809 |
| 23 | Lactic acidosis (HP:0003128) | 2.69080226 |
| 24 | 3-Methylglutaconic aciduria (HP:0003535) | 2.67921657 |
| 25 | Hepatic necrosis (HP:0002605) | 2.65974349 |
| 26 | Nephrogenic diabetes insipidus (HP:0009806) | 2.64451884 |
| 27 | Congenital primary aphakia (HP:0007707) | 2.64315429 |
| 28 | Medulloblastoma (HP:0002885) | 2.63857393 |
| 29 | B lymphocytopenia (HP:0010976) | 2.56852871 |
| 30 | Flat occiput (HP:0005469) | 2.54496864 |
| 31 | True hermaphroditism (HP:0010459) | 2.52088038 |
| 32 | Microretrognathia (HP:0000308) | 2.50281732 |
| 33 | Pancreatic fibrosis (HP:0100732) | 2.49450659 |
| 34 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.47340305 |
| 35 | Poikiloderma (HP:0001029) | 2.47307115 |
| 36 | Methylmalonic acidemia (HP:0002912) | 2.44790667 |
| 37 | Adrenal hypoplasia (HP:0000835) | 2.43395395 |
| 38 | Epiphyseal stippling (HP:0010655) | 2.40758315 |
| 39 | Pancreatic cysts (HP:0001737) | 2.39378066 |
| 40 | Gait imbalance (HP:0002141) | 2.38314928 |
| 41 | Methylmalonic aciduria (HP:0012120) | 2.26049235 |
| 42 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.22935705 |
| 43 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.22935705 |
| 44 | Entropion (HP:0000621) | 2.22748898 |
| 45 | Colon cancer (HP:0003003) | 2.21363111 |
| 46 | Hypoproteinemia (HP:0003075) | 2.19413036 |
| 47 | Tubulointerstitial nephritis (HP:0001970) | 2.18031234 |
| 48 | Chromsome breakage (HP:0040012) | 2.17585432 |
| 49 | Increased serum pyruvate (HP:0003542) | 2.16794067 |
| 50 | Progressive macrocephaly (HP:0004481) | 2.16104812 |
| 51 | Abnormality of serum amino acid levels (HP:0003112) | 2.08245335 |
| 52 | Constricted visual fields (HP:0001133) | 2.05540740 |
| 53 | CNS demyelination (HP:0007305) | 2.04679883 |
| 54 | Cerebral edema (HP:0002181) | 2.03582704 |
| 55 | Decreased testicular size (HP:0008734) | 2.01645747 |
| 56 | Lipid accumulation in hepatocytes (HP:0006561) | 1.95835755 |
| 57 | Ependymoma (HP:0002888) | 1.95646879 |
| 58 | Progressive microcephaly (HP:0000253) | 1.91614976 |
| 59 | Abnormality of the astrocytes (HP:0100707) | 1.90612602 |
| 60 | Astrocytoma (HP:0009592) | 1.90612602 |
| 61 | Abnormality of the metopic suture (HP:0005556) | 1.90494007 |
| 62 | Retinal dysplasia (HP:0007973) | 1.90198554 |
| 63 | Postnatal microcephaly (HP:0005484) | 1.89973410 |
| 64 | Female pseudohermaphroditism (HP:0010458) | 1.89401936 |
| 65 | Bile duct proliferation (HP:0001408) | 1.89322319 |
| 66 | Abnormal biliary tract physiology (HP:0012439) | 1.89322319 |
| 67 | Meckel diverticulum (HP:0002245) | 1.88383352 |
| 68 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.87282613 |
| 69 | Increased hepatocellular lipid droplets (HP:0006565) | 1.87130499 |
| 70 | Abnormality of chromosome stability (HP:0003220) | 1.87023968 |
| 71 | Progressive inability to walk (HP:0002505) | 1.86071766 |
| 72 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.83721924 |
| 73 | Postaxial foot polydactyly (HP:0001830) | 1.82647943 |
| 74 | Abnormality of midbrain morphology (HP:0002418) | 1.80735504 |
| 75 | Molar tooth sign on MRI (HP:0002419) | 1.80735504 |
| 76 | Pancytopenia (HP:0001876) | 1.80454249 |
| 77 | Split foot (HP:0001839) | 1.80035336 |
| 78 | Abnormality of the ileum (HP:0001549) | 1.79127481 |
| 79 | Severe combined immunodeficiency (HP:0004430) | 1.78224957 |
| 80 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.77995507 |
| 81 | Glioma (HP:0009733) | 1.76811770 |
| 82 | Degeneration of anterior horn cells (HP:0002398) | 1.75354595 |
| 83 | Abnormality of the anterior horn cell (HP:0006802) | 1.75354595 |
| 84 | Increased intramyocellular lipid droplets (HP:0012240) | 1.74693884 |
| 85 | Primary adrenal insufficiency (HP:0008207) | 1.74170760 |
| 86 | Vaginal atresia (HP:0000148) | 1.73926160 |
| 87 | Abnormality of glycolysis (HP:0004366) | 1.73863614 |
| 88 | Erythroderma (HP:0001019) | 1.72668153 |
| 89 | Opisthotonus (HP:0002179) | 1.72122222 |
| 90 | Rough bone trabeculation (HP:0100670) | 1.71784110 |
| 91 | Genital tract atresia (HP:0001827) | 1.71563819 |
| 92 | Respiratory failure (HP:0002878) | 1.71264835 |
| 93 | Bone marrow hypocellularity (HP:0005528) | 1.70086171 |
| 94 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.69769628 |
| 95 | Hypoplastic pelvis (HP:0008839) | 1.69657858 |
| 96 | Secondary amenorrhea (HP:0000869) | 1.69455527 |
| 97 | Exercise intolerance (HP:0003546) | 1.68592808 |
| 98 | Multicystic kidney dysplasia (HP:0000003) | 1.67659020 |
| 99 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.67221916 |
| 100 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.67221916 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SRPK1 | 3.20813523 |
| 2 | BCKDK | 3.20392422 |
| 3 | VRK2 | 3.03046332 |
| 4 | TRIM28 | 2.99116829 |
| 5 | PIM2 | 2.72954412 |
| 6 | CSNK1G3 | 2.69019090 |
| 7 | BUB1 | 2.56806509 |
| 8 | BCR | 2.55026408 |
| 9 | MAP4K2 | 2.54056032 |
| 10 | MAP2K7 | 2.53794981 |
| 11 | CSNK1A1L | 2.35830279 |
| 12 | ZAK | 2.29818351 |
| 13 | NME2 | 2.23156918 |
| 14 | CSNK1G1 | 2.21363482 |
| 15 | CSNK1G2 | 2.08507689 |
| 16 | SCYL2 | 2.06821673 |
| 17 | EIF2AK3 | 2.01062812 |
| 18 | TESK2 | 2.00045974 |
| 19 | CDK19 | 1.86636003 |
| 20 | NUAK1 | 1.77352415 |
| 21 | STK16 | 1.76208396 |
| 22 | VRK1 | 1.74602879 |
| 23 | CDC7 | 1.72247457 |
| 24 | DYRK3 | 1.69227859 |
| 25 | PBK | 1.67791505 |
| 26 | NEK1 | 1.66607175 |
| 27 | EIF2AK1 | 1.61166844 |
| 28 | MAP3K4 | 1.59141278 |
| 29 | PLK4 | 1.57694089 |
| 30 | RPS6KA4 | 1.54178609 |
| 31 | PASK | 1.47003841 |
| 32 | BRSK2 | 1.41339571 |
| 33 | KDR | 1.39574709 |
| 34 | CCNB1 | 1.38895599 |
| 35 | TESK1 | 1.36995040 |
| 36 | WEE1 | 1.35536960 |
| 37 | ERBB3 | 1.24703606 |
| 38 | PLK1 | 1.19022214 |
| 39 | MST4 | 1.15302133 |
| 40 | EPHA3 | 1.11995094 |
| 41 | ADRBK2 | 1.10170753 |
| 42 | FRK | 1.09535588 |
| 43 | RPS6KA5 | 1.06125232 |
| 44 | AURKA | 1.02870778 |
| 45 | LIMK1 | 1.01889575 |
| 46 | DYRK2 | 1.01369820 |
| 47 | ABL2 | 1.01042454 |
| 48 | ATR | 0.98770272 |
| 49 | CHEK2 | 0.90297373 |
| 50 | MAP3K12 | 0.87156301 |
| 51 | WNK3 | 0.81260313 |
| 52 | PDK2 | 0.81024081 |
| 53 | STK10 | 0.77365573 |
| 54 | MAPK13 | 0.75089500 |
| 55 | AURKB | 0.74135153 |
| 56 | TAF1 | 0.71502343 |
| 57 | TSSK6 | 0.70307999 |
| 58 | CDK9 | 0.70097189 |
| 59 | CDK6 | 0.67951768 |
| 60 | MKNK1 | 0.67038378 |
| 61 | FGR | 0.65695817 |
| 62 | CDK7 | 0.63952402 |
| 63 | MAP3K5 | 0.62777661 |
| 64 | PLK2 | 0.61535741 |
| 65 | PLK3 | 0.58726920 |
| 66 | CASK | 0.57316151 |
| 67 | ATM | 0.55567509 |
| 68 | CSNK2A1 | 0.54275101 |
| 69 | MAP3K14 | 0.53767611 |
| 70 | BRSK1 | 0.52571063 |
| 71 | PIK3CG | 0.49994431 |
| 72 | MKNK2 | 0.49799700 |
| 73 | TTK | 0.49018925 |
| 74 | CSNK1A1 | 0.42481778 |
| 75 | CDK4 | 0.41846056 |
| 76 | BMPR1B | 0.40436730 |
| 77 | CSNK2A2 | 0.39540368 |
| 78 | NME1 | 0.39378636 |
| 79 | CHEK1 | 0.39142610 |
| 80 | IKBKB | 0.35864358 |
| 81 | CDK8 | 0.35003716 |
| 82 | EPHB2 | 0.34035671 |
| 83 | PRKCE | 0.34009061 |
| 84 | BRD4 | 0.33841165 |
| 85 | TLK1 | 0.32312196 |
| 86 | RPS6KB2 | 0.30932878 |
| 87 | PAK4 | 0.30344902 |
| 88 | PKN1 | 0.29532398 |
| 89 | MAP2K4 | 0.28436916 |
| 90 | GRK7 | 0.27502629 |
| 91 | CDK14 | 0.27055264 |
| 92 | PIM1 | 0.25506663 |
| 93 | PINK1 | 0.25305283 |
| 94 | MATK | 0.25260804 |
| 95 | CAMKK2 | 0.25090231 |
| 96 | ADRBK1 | 0.24746784 |
| 97 | ITK | 0.24346199 |
| 98 | EIF2AK2 | 0.23927853 |
| 99 | MAPKAPK5 | 0.23315104 |
| 100 | CAMK2B | 0.23201806 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.00145474 |
| 2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.06469000 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.05835297 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 2.97905026 |
| 5 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.87768652 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 2.74942473 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 2.65009349 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.52326163 |
| 9 | Spliceosome_Homo sapiens_hsa03040 | 2.44081570 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.41145628 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.38274935 |
| 12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.32280586 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.28215076 |
| 14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.14397941 |
| 15 | Protein export_Homo sapiens_hsa03060 | 2.12990098 |
| 16 | RNA transport_Homo sapiens_hsa03013 | 2.07977879 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.06243605 |
| 18 | Parkinsons disease_Homo sapiens_hsa05012 | 2.03100271 |
| 19 | Ribosome_Homo sapiens_hsa03010 | 1.91403125 |
| 20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.82739407 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.62403999 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.57984327 |
| 23 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.56283012 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.46287578 |
| 25 | Cell cycle_Homo sapiens_hsa04110 | 1.44808270 |
| 26 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.37816969 |
| 27 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.35983923 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.35366462 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.34162896 |
| 30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.31955592 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.28911075 |
| 32 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.28808067 |
| 33 | Peroxisome_Homo sapiens_hsa04146 | 1.28631931 |
| 34 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.26273150 |
| 35 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.24950032 |
| 36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.23126143 |
| 37 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.22042059 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.19967090 |
| 39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.19377469 |
| 40 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.16617544 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.14439770 |
| 42 | Alzheimers disease_Homo sapiens_hsa05010 | 1.13877010 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.11093990 |
| 44 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.10211247 |
| 45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.07211372 |
| 46 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.05566479 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.02217615 |
| 48 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.01831229 |
| 49 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.01196367 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.99250961 |
| 51 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.96438368 |
| 52 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.95834488 |
| 53 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.95350955 |
| 54 | Alcoholism_Homo sapiens_hsa05034 | 0.93927786 |
| 55 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.93187553 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.90918312 |
| 57 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.89943953 |
| 58 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.84694023 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.80344730 |
| 60 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.79753783 |
| 61 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.79457121 |
| 62 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.76592728 |
| 63 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.73353457 |
| 64 | Carbon metabolism_Homo sapiens_hsa01200 | 0.72288700 |
| 65 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.70980811 |
| 66 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.66219586 |
| 67 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.61896424 |
| 68 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.55847777 |
| 69 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.55525574 |
| 70 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.53010470 |
| 71 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50925213 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49791435 |
| 73 | Legionellosis_Homo sapiens_hsa05134 | 0.49040874 |
| 74 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.48630951 |
| 75 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.48014335 |
| 76 | Shigellosis_Homo sapiens_hsa05131 | 0.46391786 |
| 77 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.45196336 |
| 78 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.40133386 |
| 79 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.36710041 |
| 80 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35862903 |
| 81 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.32413374 |
| 82 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.31840974 |
| 83 | Salmonella infection_Homo sapiens_hsa05132 | 0.28360923 |
| 84 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.27798040 |
| 85 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.27649155 |
| 86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.25362214 |
| 87 | Circadian rhythm_Homo sapiens_hsa04710 | 0.23334068 |
| 88 | Apoptosis_Homo sapiens_hsa04210 | 0.20724466 |
| 89 | Phototransduction_Homo sapiens_hsa04744 | 0.20389305 |
| 90 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.18593551 |
| 91 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.17993831 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.17775960 |
| 93 | Hepatitis B_Homo sapiens_hsa05161 | 0.17278892 |
| 94 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.14492847 |
| 95 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.13985775 |
| 96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.12377526 |
| 97 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.10819694 |
| 98 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.09156880 |
| 99 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.08681190 |
| 100 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.07706497 |

