

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.61890683 |
| 2 | cytidine deamination (GO:0009972) | 6.02937144 |
| 3 | cytidine metabolic process (GO:0046087) | 6.02937144 |
| 4 | cytidine catabolic process (GO:0006216) | 6.02937144 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.87347114 |
| 6 | proteasome assembly (GO:0043248) | 5.25660597 |
| 7 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.15556813 |
| 8 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.63575379 |
| 9 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.48124998 |
| 10 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.30172080 |
| 11 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.25910867 |
| 12 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.22654703 |
| 13 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.19864184 |
| 14 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.19864184 |
| 15 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.19864184 |
| 16 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.19106927 |
| 17 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.19106927 |
| 18 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.09545050 |
| 19 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.08678715 |
| 20 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.02275789 |
| 21 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.02275789 |
| 22 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.01919173 |
| 23 | negative regulation of ligase activity (GO:0051352) | 4.00131456 |
| 24 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.00131456 |
| 25 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.98265278 |
| 26 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.96944745 |
| 27 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.96944745 |
| 28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.96736442 |
| 29 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.87581927 |
| 30 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.83908151 |
| 31 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.76474305 |
| 32 | protein complex biogenesis (GO:0070271) | 3.73586864 |
| 33 | ATP synthesis coupled proton transport (GO:0015986) | 3.71444064 |
| 34 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.71444064 |
| 35 | regulation of chronic inflammatory response (GO:0002676) | 3.65627184 |
| 36 | chaperone-mediated protein transport (GO:0072321) | 3.63830579 |
| 37 | GTP biosynthetic process (GO:0006183) | 3.58539274 |
| 38 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.54314874 |
| 39 | cellular response to interleukin-15 (GO:0071350) | 3.52018286 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.48860359 |
| 41 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.45611999 |
| 42 | positive regulation of ligase activity (GO:0051351) | 3.43523301 |
| 43 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.40125128 |
| 44 | regulation of cellular amine metabolic process (GO:0033238) | 3.39170531 |
| 45 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.34100047 |
| 46 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.34100047 |
| 47 | NADH dehydrogenase complex assembly (GO:0010257) | 3.34100047 |
| 48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.32880697 |
| 49 | platelet dense granule organization (GO:0060155) | 3.30145357 |
| 50 | positive regulation of cell cycle arrest (GO:0071158) | 3.28955691 |
| 51 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.27174650 |
| 52 | protein deneddylation (GO:0000338) | 3.24690318 |
| 53 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.23506583 |
| 54 | regulation of activation of Janus kinase activity (GO:0010533) | 3.20025272 |
| 55 | cullin deneddylation (GO:0010388) | 3.18637221 |
| 56 | respiratory chain complex IV assembly (GO:0008535) | 3.14668442 |
| 57 | response to pheromone (GO:0019236) | 3.08750066 |
| 58 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.05148920 |
| 59 | electron transport chain (GO:0022900) | 3.04503267 |
| 60 | respiratory electron transport chain (GO:0022904) | 3.03954667 |
| 61 | pseudouridine synthesis (GO:0001522) | 3.01977492 |
| 62 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.96452753 |
| 63 | cytochrome complex assembly (GO:0017004) | 2.95546320 |
| 64 | DNA double-strand break processing (GO:0000729) | 2.95204089 |
| 65 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.94858027 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 2.94324287 |
| 67 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.94324287 |
| 68 | UTP biosynthetic process (GO:0006228) | 2.93920647 |
| 69 | rRNA modification (GO:0000154) | 2.91394007 |
| 70 | regulation of ligase activity (GO:0051340) | 2.88458504 |
| 71 | regulation of immunoglobulin secretion (GO:0051023) | 2.84242575 |
| 72 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.84185563 |
| 73 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.79576243 |
| 74 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.79021441 |
| 75 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.77269516 |
| 76 | negative regulation of protein ubiquitination (GO:0031397) | 2.75329878 |
| 77 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.70964892 |
| 78 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.70964892 |
| 79 | regulation of cell cycle arrest (GO:0071156) | 2.70751613 |
| 80 | negative regulation by host of viral transcription (GO:0043922) | 2.69573839 |
| 81 | maturation of 5.8S rRNA (GO:0000460) | 2.69000163 |
| 82 | response to interleukin-15 (GO:0070672) | 2.68767325 |
| 83 | amino acid salvage (GO:0043102) | 2.65422159 |
| 84 | L-methionine salvage (GO:0071267) | 2.65422159 |
| 85 | L-methionine biosynthetic process (GO:0071265) | 2.65422159 |
| 86 | tRNA processing (GO:0008033) | 2.65365180 |
| 87 | protein targeting to mitochondrion (GO:0006626) | 2.64938911 |
| 88 | base-excision repair, AP site formation (GO:0006285) | 2.63158509 |
| 89 | signal transduction in response to DNA damage (GO:0042770) | 2.63148577 |
| 90 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.63073777 |
| 91 | rRNA methylation (GO:0031167) | 2.61006808 |
| 92 | protein neddylation (GO:0045116) | 2.60638506 |
| 93 | aldehyde catabolic process (GO:0046185) | 2.60028081 |
| 94 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.58630875 |
| 95 | signal peptide processing (GO:0006465) | 2.58362881 |
| 96 | tRNA metabolic process (GO:0006399) | 2.57728242 |
| 97 | negative regulation of protein modification by small protein conjugation or removal (GO:1903321) | 2.57369304 |
| 98 | mannosylation (GO:0097502) | 2.56199288 |
| 99 | UTP metabolic process (GO:0046051) | 2.54922684 |
| 100 | positive regulation of defense response to virus by host (GO:0002230) | 2.54742600 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.12296444 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.33034249 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.85082063 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.84321953 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.83025883 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.80614898 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.59663538 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.33251937 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.12966755 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.81586997 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.72010470 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.68245162 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.63360801 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.60265447 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.53574898 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.47975262 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.35017555 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.31924606 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.29608578 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.28575627 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.23028385 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.16771528 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.07711398 |
| 24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.04762237 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.92458835 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.89777486 |
| 27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.87588713 |
| 28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.78190759 |
| 29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.71248719 |
| 30 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.71091678 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.70622640 |
| 32 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.63580851 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.60636693 |
| 34 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.60487302 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.60402098 |
| 36 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.56234594 |
| 37 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.55988126 |
| 38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.54415121 |
| 39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.47694993 |
| 40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.44342784 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.41742790 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.40665570 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.39664909 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.38679569 |
| 45 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.38078454 |
| 46 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.35165390 |
| 47 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.33863759 |
| 48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.32995855 |
| 49 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.30095481 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29479306 |
| 51 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.29032098 |
| 52 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.28155393 |
| 53 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26768229 |
| 54 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.23719501 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22000536 |
| 56 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.21914962 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.21161054 |
| 58 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.19820682 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.18642558 |
| 60 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.18259765 |
| 61 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14856786 |
| 62 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.14620216 |
| 63 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14619182 |
| 64 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14619182 |
| 65 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13781798 |
| 66 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.11817519 |
| 67 | GATA3_26560356_Chip-Seq_TH2_Human | 1.11789467 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10232620 |
| 69 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10038606 |
| 70 | AR_20517297_ChIP-Seq_VCAP_Human | 1.09820524 |
| 71 | MYB_26560356_Chip-Seq_TH2_Human | 1.09674903 |
| 72 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.09587090 |
| 73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.08206276 |
| 74 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.07046239 |
| 75 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.04766777 |
| 76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.04267920 |
| 77 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.04139945 |
| 78 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.02673686 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02323439 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02323439 |
| 81 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02004602 |
| 82 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.01883091 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00391853 |
| 84 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.99238739 |
| 85 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.98758418 |
| 86 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.97225770 |
| 87 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.96545127 |
| 88 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.95822736 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.95739844 |
| 90 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94446273 |
| 91 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.93508957 |
| 92 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.92907709 |
| 93 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.92252748 |
| 94 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.91478927 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90217718 |
| 96 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.89152813 |
| 97 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85739452 |
| 98 | NCOR_22424771_ChIP-Seq_293T_Human | 0.85689247 |
| 99 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.81832738 |
| 100 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.80391485 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 4.12096107 |
| 2 | MP0005671_abnormal_response_to | 3.70957075 |
| 3 | MP0000372_irregular_coat_pigmentation | 3.16956422 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.79333982 |
| 5 | MP0003806_abnormal_nucleotide_metabolis | 2.69073509 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.48574589 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 2.25815100 |
| 8 | MP0009785_altered_susceptibility_to | 2.25412682 |
| 9 | MP0003786_premature_aging | 2.24623783 |
| 10 | MP0001873_stomach_inflammation | 2.23252333 |
| 11 | MP0008872_abnormal_physiological_respon | 2.21335610 |
| 12 | MP0003195_calcinosis | 2.05809654 |
| 13 | MP0004147_increased_porphyrin_level | 2.00982220 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 1.97436926 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 1.92907471 |
| 16 | MP0003878_abnormal_ear_physiology | 1.92529020 |
| 17 | MP0005377_hearing/vestibular/ear_phenot | 1.92529020 |
| 18 | MP0008058_abnormal_DNA_repair | 1.89874504 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.88796763 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.85962398 |
| 21 | MP0006072_abnormal_retinal_apoptosis | 1.83309245 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.83302690 |
| 23 | MP0001348_abnormal_lacrimal_gland | 1.79011558 |
| 24 | MP0002736_abnormal_nociception_after | 1.75798552 |
| 25 | MP0001529_abnormal_vocalization | 1.73001681 |
| 26 | MP0003718_maternal_effect | 1.68145548 |
| 27 | MP0003186_abnormal_redox_activity | 1.61692703 |
| 28 | MP0001919_abnormal_reproductive_system | 1.60785582 |
| 29 | MP0001800_abnormal_humoral_immune | 1.55775688 |
| 30 | MP0010094_abnormal_chromosome_stability | 1.55733339 |
| 31 | MP0002876_abnormal_thyroid_physiology | 1.52642970 |
| 32 | MP0002166_altered_tumor_susceptibility | 1.50486903 |
| 33 | MP0006082_CNS_inflammation | 1.48514487 |
| 34 | MP0002006_tumorigenesis | 1.47714058 |
| 35 | MP0006292_abnormal_olfactory_placode | 1.46002551 |
| 36 | MP0005000_abnormal_immune_tolerance | 1.45558013 |
| 37 | MP0001853_heart_inflammation | 1.45465418 |
| 38 | MP0005387_immune_system_phenotype | 1.43588465 |
| 39 | MP0001790_abnormal_immune_system | 1.43588465 |
| 40 | MP0004145_abnormal_muscle_electrophysio | 1.42791753 |
| 41 | MP0003763_abnormal_thymus_physiology | 1.40922669 |
| 42 | MP0008877_abnormal_DNA_methylation | 1.40838877 |
| 43 | MP0006054_spinal_hemorrhage | 1.40568136 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.39671391 |
| 45 | MP0001905_abnormal_dopamine_level | 1.38343481 |
| 46 | MP0005253_abnormal_eye_physiology | 1.35613859 |
| 47 | MP0003693_abnormal_embryo_hatching | 1.34089516 |
| 48 | MP0000685_abnormal_immune_system | 1.32704504 |
| 49 | MP0002163_abnormal_gland_morphology | 1.32371828 |
| 50 | MP0001968_abnormal_touch/_nociception | 1.27602723 |
| 51 | MP0002723_abnormal_immune_serum | 1.27381642 |
| 52 | MP0003646_muscle_fatigue | 1.23533948 |
| 53 | MP0002277_abnormal_respiratory_mucosa | 1.22407946 |
| 54 | MP0003011_delayed_dark_adaptation | 1.21388192 |
| 55 | MP0006035_abnormal_mitochondrial_morpho | 1.21086369 |
| 56 | MP0003567_abnormal_fetal_cardiomyocyte | 1.21038764 |
| 57 | MP0002234_abnormal_pharynx_morphology | 1.15813464 |
| 58 | MP0002420_abnormal_adaptive_immunity | 1.14672417 |
| 59 | MP0005389_reproductive_system_phenotype | 1.12264374 |
| 60 | MP0005551_abnormal_eye_electrophysiolog | 1.11967502 |
| 61 | MP0004957_abnormal_blastocyst_morpholog | 1.08257155 |
| 62 | MP0005410_abnormal_fertilization | 1.08238849 |
| 63 | MP0001819_abnormal_immune_cell | 1.08193295 |
| 64 | MP0003866_abnormal_defecation | 1.07414257 |
| 65 | MP0005379_endocrine/exocrine_gland_phen | 1.03005093 |
| 66 | MP0005360_urolithiasis | 1.02220955 |
| 67 | MP0002405_respiratory_system_inflammati | 1.01939362 |
| 68 | MP0002452_abnormal_antigen_presenting | 1.01728817 |
| 69 | MP0001984_abnormal_olfaction | 0.98730204 |
| 70 | MP0005025_abnormal_response_to | 0.98187354 |
| 71 | MP0003283_abnormal_digestive_organ | 0.98132823 |
| 72 | MP0003137_abnormal_impulse_conducting | 0.95345209 |
| 73 | MP0002139_abnormal_hepatobiliary_system | 0.93674112 |
| 74 | MP0005408_hypopigmentation | 0.93163304 |
| 75 | MP0001845_abnormal_inflammatory_respons | 0.92725149 |
| 76 | MP0001764_abnormal_homeostasis | 0.91234328 |
| 77 | MP0005085_abnormal_gallbladder_physiolo | 0.90416835 |
| 78 | MP0004742_abnormal_vestibular_system | 0.89697400 |
| 79 | MP0000689_abnormal_spleen_morphology | 0.88186852 |
| 80 | MP0005332_abnormal_amino_acid | 0.87061948 |
| 81 | MP0002398_abnormal_bone_marrow | 0.86977235 |
| 82 | MP0004782_abnormal_surfactant_physiolog | 0.85430219 |
| 83 | MP0000716_abnormal_immune_system | 0.84794628 |
| 84 | MP0000465_gastrointestinal_hemorrhage | 0.84360825 |
| 85 | MP0005636_abnormal_mineral_homeostasis | 0.84029162 |
| 86 | MP0005395_other_phenotype | 0.83979589 |
| 87 | MP0008007_abnormal_cellular_replicative | 0.83880545 |
| 88 | MP0002938_white_spotting | 0.79130109 |
| 89 | MP0010386_abnormal_urinary_bladder | 0.78178965 |
| 90 | MP0005310_abnormal_salivary_gland | 0.76237918 |
| 91 | MP0001485_abnormal_pinna_reflex | 0.74094719 |
| 92 | MP0002429_abnormal_blood_cell | 0.73654173 |
| 93 | MP0001119_abnormal_female_reproductive | 0.73008491 |
| 94 | MP0002722_abnormal_immune_system | 0.72773011 |
| 95 | MP0001501_abnormal_sleep_pattern | 0.72109417 |
| 96 | MP0009745_abnormal_behavioral_response | 0.71703421 |
| 97 | MP0008995_early_reproductive_senescence | 0.71606669 |
| 98 | MP0003111_abnormal_nucleus_morphology | 0.70742007 |
| 99 | MP0004142_abnormal_muscle_tone | 0.70359111 |
| 100 | MP0004215_abnormal_myocardial_fiber | 0.69099054 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.61043545 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.38361943 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.27211843 |
| 4 | Acute encephalopathy (HP:0006846) | 4.24135018 |
| 5 | Increased CSF lactate (HP:0002490) | 4.13306597 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.97437160 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.87018108 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.82754418 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.73548668 |
| 10 | Hepatic necrosis (HP:0002605) | 3.58344155 |
| 11 | IgG deficiency (HP:0004315) | 3.50068979 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 3.34834057 |
| 13 | Cerebral edema (HP:0002181) | 3.21234995 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.19146446 |
| 15 | Increased serum lactate (HP:0002151) | 3.16323898 |
| 16 | Aplastic anemia (HP:0001915) | 3.12526434 |
| 17 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.04810880 |
| 18 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.04810880 |
| 19 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.03551897 |
| 20 | Hypoproteinemia (HP:0003075) | 3.00673819 |
| 21 | Lactic acidosis (HP:0003128) | 2.79195177 |
| 22 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.78093342 |
| 23 | Abnormality of T cell number (HP:0011839) | 2.77209173 |
| 24 | Chronic diarrhea (HP:0002028) | 2.76663595 |
| 25 | T lymphocytopenia (HP:0005403) | 2.65658373 |
| 26 | Increased muscle lipid content (HP:0009058) | 2.65464159 |
| 27 | Increased IgM level (HP:0003496) | 2.63247408 |
| 28 | Type I transferrin isoform profile (HP:0003642) | 2.62717390 |
| 29 | Stomatitis (HP:0010280) | 2.58343453 |
| 30 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.56935779 |
| 31 | Optic disc pallor (HP:0000543) | 2.55188776 |
| 32 | Exercise intolerance (HP:0003546) | 2.52300766 |
| 33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.50186284 |
| 34 | Severe combined immunodeficiency (HP:0004430) | 2.48668691 |
| 35 | Methylmalonic acidemia (HP:0002912) | 2.43317576 |
| 36 | Lethargy (HP:0001254) | 2.37126502 |
| 37 | Methylmalonic aciduria (HP:0012120) | 2.36860979 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.35375000 |
| 39 | Molar tooth sign on MRI (HP:0002419) | 2.35375000 |
| 40 | Abnormality of T cells (HP:0002843) | 2.34887925 |
| 41 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.34818637 |
| 42 | Exertional dyspnea (HP:0002875) | 2.33297604 |
| 43 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.30926065 |
| 44 | Respiratory failure (HP:0002878) | 2.30641109 |
| 45 | CNS demyelination (HP:0007305) | 2.30615623 |
| 46 | Oral leukoplakia (HP:0002745) | 2.26977982 |
| 47 | Type 2 muscle fiber atrophy (HP:0003554) | 2.25732402 |
| 48 | Pancreatic cysts (HP:0001737) | 2.24949400 |
| 49 | Hyperglycinemia (HP:0002154) | 2.22069721 |
| 50 | Abolished electroretinogram (ERG) (HP:0000550) | 2.21670738 |
| 51 | Pancytopenia (HP:0001876) | 2.18978528 |
| 52 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.18155539 |
| 53 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.18155539 |
| 54 | Abnormal protein glycosylation (HP:0012346) | 2.18155539 |
| 55 | Abnormal glycosylation (HP:0012345) | 2.18155539 |
| 56 | Microvesicular hepatic steatosis (HP:0001414) | 2.16361665 |
| 57 | Renal cortical cysts (HP:0000803) | 2.14364191 |
| 58 | Abnormality of placental membranes (HP:0011409) | 2.14131492 |
| 59 | Amniotic constriction ring (HP:0009775) | 2.14131492 |
| 60 | Generalized aminoaciduria (HP:0002909) | 2.13871172 |
| 61 | Reduced antithrombin III activity (HP:0001976) | 2.12068061 |
| 62 | Abnormality of eosinophils (HP:0001879) | 2.11399925 |
| 63 | Cerebral hypomyelination (HP:0006808) | 2.09093863 |
| 64 | Congenital stationary night blindness (HP:0007642) | 2.08616038 |
| 65 | Hypoplasia of the uterus (HP:0000013) | 2.08323957 |
| 66 | Leukodystrophy (HP:0002415) | 2.07130916 |
| 67 | Thyroiditis (HP:0100646) | 2.06929206 |
| 68 | Abnormality of serum amino acid levels (HP:0003112) | 2.05546413 |
| 69 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.05401432 |
| 70 | Abnormality of glycine metabolism (HP:0010895) | 2.05401432 |
| 71 | Increased serum pyruvate (HP:0003542) | 2.02010065 |
| 72 | Abnormality of alanine metabolism (HP:0010916) | 2.01159601 |
| 73 | Hyperalaninemia (HP:0003348) | 2.01159601 |
| 74 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.01159601 |
| 75 | Abnormality of the renal cortex (HP:0011035) | 2.00448973 |
| 76 | Hyperglycinuria (HP:0003108) | 2.00111857 |
| 77 | Abnormality of the anterior horn cell (HP:0006802) | 1.99803657 |
| 78 | Degeneration of anterior horn cells (HP:0002398) | 1.99803657 |
| 79 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.98179619 |
| 80 | Abnormality of the labia minora (HP:0012880) | 1.96287253 |
| 81 | Muscle fiber atrophy (HP:0100295) | 1.96098930 |
| 82 | Abnormality of the prostate (HP:0008775) | 1.94010520 |
| 83 | Glycosuria (HP:0003076) | 1.92657259 |
| 84 | Abnormality of urine glucose concentration (HP:0011016) | 1.92657259 |
| 85 | Respiratory difficulties (HP:0002880) | 1.92608929 |
| 86 | Abnormal albumin level (HP:0012116) | 1.92599041 |
| 87 | Hypoalbuminemia (HP:0003073) | 1.92599041 |
| 88 | Keratoconus (HP:0000563) | 1.88306231 |
| 89 | Increased corneal curvature (HP:0100692) | 1.88306231 |
| 90 | Abnormality of glycolysis (HP:0004366) | 1.86997023 |
| 91 | Abnormality of methionine metabolism (HP:0010901) | 1.85508202 |
| 92 | Abnormality of renal resorption (HP:0011038) | 1.85235586 |
| 93 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.84900301 |
| 94 | True hermaphroditism (HP:0010459) | 1.84093096 |
| 95 | Combined immunodeficiency (HP:0005387) | 1.84060851 |
| 96 | Progressive microcephaly (HP:0000253) | 1.83938365 |
| 97 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.80041960 |
| 98 | Dicarboxylic aciduria (HP:0003215) | 1.80041960 |
| 99 | Emotional lability (HP:0000712) | 1.79799301 |
| 100 | Pendular nystagmus (HP:0012043) | 1.78935253 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.54992922 |
| 2 | TXK | 3.40657102 |
| 3 | BUB1 | 3.20332767 |
| 4 | ZAK | 3.05608391 |
| 5 | TLK1 | 2.68069801 |
| 6 | VRK1 | 2.61526628 |
| 7 | EIF2AK3 | 2.57207984 |
| 8 | MAP3K12 | 2.52108621 |
| 9 | BCKDK | 2.51066288 |
| 10 | EIF2AK1 | 2.39571322 |
| 11 | PBK | 2.24021453 |
| 12 | MST4 | 2.21218556 |
| 13 | TSSK6 | 2.10838346 |
| 14 | KDR | 2.10272800 |
| 15 | NUAK1 | 2.07110772 |
| 16 | MAP4K2 | 1.98663533 |
| 17 | TRIM28 | 1.85351454 |
| 18 | ADRBK2 | 1.81283860 |
| 19 | SRPK1 | 1.72497911 |
| 20 | PINK1 | 1.61539880 |
| 21 | NEK1 | 1.60423029 |
| 22 | INSRR | 1.59948184 |
| 23 | NME1 | 1.51385602 |
| 24 | PDK2 | 1.51352912 |
| 25 | GRK1 | 1.48717594 |
| 26 | TESK2 | 1.45189502 |
| 27 | PLK3 | 1.39634957 |
| 28 | BCR | 1.33034626 |
| 29 | WEE1 | 1.30984076 |
| 30 | TAF1 | 1.28016251 |
| 31 | MAPKAPK3 | 1.22962162 |
| 32 | BMPR1B | 1.20360511 |
| 33 | CSNK1G3 | 1.17414238 |
| 34 | STK16 | 1.16720944 |
| 35 | TIE1 | 1.11451080 |
| 36 | PLK2 | 1.09802431 |
| 37 | MAP4K1 | 1.09461669 |
| 38 | CCNB1 | 1.08189311 |
| 39 | STK39 | 1.07404835 |
| 40 | DAPK1 | 1.00808964 |
| 41 | FRK | 0.99652168 |
| 42 | CSNK1G2 | 0.97404411 |
| 43 | TNIK | 0.94019296 |
| 44 | TAOK3 | 0.93502836 |
| 45 | EIF2AK2 | 0.92245423 |
| 46 | CSNK1G1 | 0.90834413 |
| 47 | WNK3 | 0.90468491 |
| 48 | TEC | 0.89660333 |
| 49 | DYRK2 | 0.89110505 |
| 50 | OXSR1 | 0.88421251 |
| 51 | SCYL2 | 0.87479548 |
| 52 | ITK | 0.86710847 |
| 53 | WNK4 | 0.84017204 |
| 54 | CSNK1A1L | 0.82255760 |
| 55 | PLK4 | 0.78508309 |
| 56 | MYLK | 0.77977955 |
| 57 | MAP2K6 | 0.76654149 |
| 58 | IKBKB | 0.74580858 |
| 59 | RPS6KA5 | 0.71181870 |
| 60 | BRSK2 | 0.70449215 |
| 61 | PRKCQ | 0.68387380 |
| 62 | MAPK13 | 0.64129543 |
| 63 | FES | 0.63647359 |
| 64 | LIMK1 | 0.61597659 |
| 65 | PAK3 | 0.59354362 |
| 66 | SYK | 0.55982065 |
| 67 | GRK6 | 0.54116384 |
| 68 | TESK1 | 0.53831096 |
| 69 | MAPKAPK5 | 0.53197307 |
| 70 | PLK1 | 0.52059322 |
| 71 | PAK4 | 0.51940417 |
| 72 | KIT | 0.51850186 |
| 73 | ATR | 0.51584853 |
| 74 | ERBB3 | 0.46651499 |
| 75 | DAPK3 | 0.46420626 |
| 76 | GRK5 | 0.45645363 |
| 77 | AURKA | 0.45094957 |
| 78 | AURKB | 0.44643499 |
| 79 | PIK3CG | 0.44289703 |
| 80 | STK38L | 0.43736519 |
| 81 | LCK | 0.42271852 |
| 82 | CSNK2A1 | 0.41649125 |
| 83 | MKNK2 | 0.39395247 |
| 84 | CDC7 | 0.38335382 |
| 85 | PRKCE | 0.37185254 |
| 86 | CAMKK2 | 0.34734668 |
| 87 | CSNK2A2 | 0.34100034 |
| 88 | OBSCN | 0.34056048 |
| 89 | LYN | 0.32745146 |
| 90 | MKNK1 | 0.31296379 |
| 91 | IGF1R | 0.30565797 |
| 92 | CASK | 0.29625077 |
| 93 | PASK | 0.29527303 |
| 94 | PAK6 | 0.28950635 |
| 95 | PRKCG | 0.27654335 |
| 96 | CSNK1A1 | 0.26139337 |
| 97 | PRKCI | 0.26066380 |
| 98 | MAP3K11 | 0.25960152 |
| 99 | IKBKE | 0.25324328 |
| 100 | NLK | 0.24932090 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.52407753 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.93744663 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.91737906 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.62599757 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.57251495 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.40079765 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.33828886 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.16376535 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.06518888 |
| 10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.78913525 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.77737989 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.71040189 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.68197981 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.66705183 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.66457298 |
| 16 | Asthma_Homo sapiens_hsa05310 | 1.65036793 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.64367278 |
| 18 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.64199209 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.58170352 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.57712690 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.57569361 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.42229081 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.41649345 |
| 24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.41037970 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.38422290 |
| 26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.38078923 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.37899284 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.37588751 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32278036 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.30786482 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.29001562 |
| 32 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.28959475 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.28891500 |
| 34 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.27251539 |
| 35 | RNA degradation_Homo sapiens_hsa03018 | 1.22791276 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.20559390 |
| 37 | Base excision repair_Homo sapiens_hsa03410 | 1.17821238 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.16916901 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.16236183 |
| 40 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.14316950 |
| 41 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.13454336 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 1.05329063 |
| 43 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.05294079 |
| 44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.05139214 |
| 45 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.04785928 |
| 46 | Phototransduction_Homo sapiens_hsa04744 | 1.03177474 |
| 47 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.03071093 |
| 48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.03017673 |
| 49 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.01284449 |
| 50 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.00372027 |
| 51 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.00022875 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.99664966 |
| 53 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.97356953 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.95783797 |
| 55 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.92362022 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.88528292 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.87612552 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.87427956 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85858545 |
| 60 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.82273439 |
| 61 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.80688922 |
| 62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.79298313 |
| 63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.77369862 |
| 64 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.75559901 |
| 65 | Ribosome_Homo sapiens_hsa03010 | 0.74086766 |
| 66 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.71323574 |
| 67 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.71183607 |
| 68 | Alcoholism_Homo sapiens_hsa05034 | 0.69796225 |
| 69 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.67842206 |
| 70 | Carbon metabolism_Homo sapiens_hsa01200 | 0.66441741 |
| 71 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.65757816 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61287304 |
| 73 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.60972190 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.60936038 |
| 75 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.56523561 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54241998 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.53001252 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52389409 |
| 79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50239423 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50133064 |
| 81 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.47670884 |
| 82 | Viral myocarditis_Homo sapiens_hsa05416 | 0.46074779 |
| 83 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44251653 |
| 84 | Measles_Homo sapiens_hsa05162 | 0.42994005 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42555095 |
| 86 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.42369175 |
| 87 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.41439249 |
| 88 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.41098902 |
| 89 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40548024 |
| 90 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40274620 |
| 91 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.39559735 |
| 92 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39545788 |
| 93 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.39368755 |
| 94 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.39166479 |
| 95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.38989783 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38539702 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37107599 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36331002 |
| 99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.35788382 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.33725349 |

