

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 8.46070563 |
| 2 | DNA unwinding involved in DNA replication (GO:0006268) | 8.12618048 |
| 3 | tryptophan catabolic process (GO:0006569) | 8.01734525 |
| 4 | indole-containing compound catabolic process (GO:0042436) | 8.01734525 |
| 5 | indolalkylamine catabolic process (GO:0046218) | 8.01734525 |
| 6 | kynurenine metabolic process (GO:0070189) | 7.77082689 |
| 7 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 7.19935967 |
| 8 | tryptophan metabolic process (GO:0006568) | 7.05887649 |
| 9 | terpenoid biosynthetic process (GO:0016114) | 6.59281269 |
| 10 | diterpenoid biosynthetic process (GO:0016102) | 6.24894943 |
| 11 | indolalkylamine metabolic process (GO:0006586) | 5.33025729 |
| 12 | lysine metabolic process (GO:0006553) | 5.11592253 |
| 13 | lysine catabolic process (GO:0006554) | 5.11592253 |
| 14 | embryonic camera-type eye development (GO:0031076) | 5.10870314 |
| 15 | regulation of cilium movement (GO:0003352) | 4.89140293 |
| 16 | cellular biogenic amine catabolic process (GO:0042402) | 4.80257118 |
| 17 | amine catabolic process (GO:0009310) | 4.80257118 |
| 18 | negative regulation of cAMP-mediated signaling (GO:0043951) | 4.74468339 |
| 19 | regulation of microtubule-based movement (GO:0060632) | 4.67242178 |
| 20 | positive regulation of circadian rhythm (GO:0042753) | 4.53401095 |
| 21 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.51157896 |
| 22 | aromatic amino acid family catabolic process (GO:0009074) | 4.38462691 |
| 23 | autophagic vacuole fusion (GO:0000046) | 4.33093220 |
| 24 | DNA strand elongation (GO:0022616) | 4.18418615 |
| 25 | regulation of inclusion body assembly (GO:0090083) | 4.13847702 |
| 26 | organelle membrane fusion (GO:0090174) | 4.13799306 |
| 27 | regulation of transcription elongation from RNA polymerase II promoter (GO:0034243) | 4.01452683 |
| 28 | cAMP catabolic process (GO:0006198) | 4.00817260 |
| 29 | histone H2B ubiquitination (GO:0033523) | 3.86391761 |
| 30 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.83037770 |
| 31 | isotype switching (GO:0045190) | 3.83037770 |
| 32 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.83037770 |
| 33 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.62957926 |
| 34 | DNA replication initiation (GO:0006270) | 3.59719109 |
| 35 | regulation of memory T cell differentiation (GO:0043380) | 3.52970580 |
| 36 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.52783736 |
| 37 | DNA deamination (GO:0045006) | 3.52130689 |
| 38 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.51240558 |
| 39 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.45081350 |
| 40 | nucleotide transmembrane transport (GO:1901679) | 3.43770561 |
| 41 | indole-containing compound metabolic process (GO:0042430) | 3.43169126 |
| 42 | benzene-containing compound metabolic process (GO:0042537) | 3.41898410 |
| 43 | aspartate family amino acid catabolic process (GO:0009068) | 3.40863952 |
| 44 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.40364238 |
| 45 | mammary gland epithelial cell proliferation (GO:0033598) | 3.34001874 |
| 46 | cyclic nucleotide catabolic process (GO:0009214) | 3.31270198 |
| 47 | morphogenesis of an epithelial fold (GO:0060571) | 3.30766410 |
| 48 | negative regulation of epidermal cell differentiation (GO:0045605) | 3.28471083 |
| 49 | hypotonic response (GO:0006971) | 3.26250839 |
| 50 | L-fucose catabolic process (GO:0042355) | 3.25570828 |
| 51 | fucose catabolic process (GO:0019317) | 3.25570828 |
| 52 | L-fucose metabolic process (GO:0042354) | 3.25570828 |
| 53 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 3.25549690 |
| 54 | regulation of timing of cell differentiation (GO:0048505) | 3.25477036 |
| 55 | response to folic acid (GO:0051593) | 3.22054119 |
| 56 | response to misfolded protein (GO:0051788) | 3.21319624 |
| 57 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 3.18075389 |
| 58 | retinal metabolic process (GO:0042574) | 3.17847303 |
| 59 | positive regulation of DNA repair (GO:0045739) | 3.13783982 |
| 60 | organ formation (GO:0048645) | 3.08086316 |
| 61 | protein K11-linked deubiquitination (GO:0035871) | 3.07815614 |
| 62 | non-recombinational repair (GO:0000726) | 3.07554157 |
| 63 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.07554157 |
| 64 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 3.05476790 |
| 65 | phosphorelay signal transduction system (GO:0000160) | 3.04215183 |
| 66 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.98910910 |
| 67 | acrosome reaction (GO:0007340) | 2.98352682 |
| 68 | cytochrome complex assembly (GO:0017004) | 2.97514956 |
| 69 | regulation of development, heterochronic (GO:0040034) | 2.97210388 |
| 70 | piRNA metabolic process (GO:0034587) | 2.96408681 |
| 71 | mitotic sister chromatid segregation (GO:0000070) | 2.95474817 |
| 72 | Golgi to endosome transport (GO:0006895) | 2.94798678 |
| 73 | aromatic amino acid family metabolic process (GO:0009072) | 2.94072502 |
| 74 | positive regulation of cAMP-mediated signaling (GO:0043950) | 2.92315096 |
| 75 | positive regulation of prostaglandin secretion (GO:0032308) | 2.87925970 |
| 76 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.87127638 |
| 77 | mannosylation (GO:0097502) | 2.86956477 |
| 78 | histone mRNA catabolic process (GO:0071044) | 2.86395635 |
| 79 | positive regulation of defense response to virus by host (GO:0002230) | 2.84533681 |
| 80 | ganglion development (GO:0061548) | 2.79057889 |
| 81 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.77356275 |
| 82 | protein-cofactor linkage (GO:0018065) | 2.72990283 |
| 83 | lateral sprouting from an epithelium (GO:0060601) | 2.72851564 |
| 84 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 2.71065194 |
| 85 | type B pancreatic cell proliferation (GO:0044342) | 2.71058578 |
| 86 | oxidative phosphorylation (GO:0006119) | 2.70289859 |
| 87 | negative regulation of smoothened signaling pathway (GO:0045879) | 2.69165928 |
| 88 | histone H2A ubiquitination (GO:0033522) | 2.68261974 |
| 89 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.68164803 |
| 90 | regulation of prostaglandin secretion (GO:0032306) | 2.68121863 |
| 91 | respiratory chain complex IV assembly (GO:0008535) | 2.63723025 |
| 92 | mitochondrial DNA replication (GO:0006264) | 2.60783412 |
| 93 | branch elongation of an epithelium (GO:0060602) | 2.56652538 |
| 94 | retinol metabolic process (GO:0042572) | 2.56517172 |
| 95 | macroautophagy (GO:0016236) | 2.53448210 |
| 96 | retina layer formation (GO:0010842) | 2.53360595 |
| 97 | magnesium ion transport (GO:0015693) | 2.52986726 |
| 98 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.52117202 |
| 99 | somite development (GO:0061053) | 2.48127754 |
| 100 | recombinational repair (GO:0000725) | 2.47707424 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.14457605 |
| 2 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 4.45215054 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.77407043 |
| 4 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.42742743 |
| 5 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 3.40214131 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.86108812 |
| 7 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.64461412 |
| 8 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.54927964 |
| 9 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.33980729 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.32617718 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.18259471 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.15404913 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.11762173 |
| 14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.08081335 |
| 15 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 2.05614413 |
| 16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.04494777 |
| 17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.99653915 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.95328453 |
| 19 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.94921851 |
| 20 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.91524155 |
| 21 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.86446219 |
| 22 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.78971727 |
| 23 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.77728708 |
| 24 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.75060532 |
| 25 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74071443 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.62819120 |
| 27 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.60669088 |
| 28 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.58378012 |
| 29 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.54091809 |
| 30 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.50776787 |
| 31 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.48388368 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.44840611 |
| 33 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.43573004 |
| 34 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.41544852 |
| 35 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.40543801 |
| 36 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.37982195 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.37169713 |
| 38 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.36718647 |
| 39 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.36348386 |
| 40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33612125 |
| 41 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.30201544 |
| 42 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.28626604 |
| 43 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28567377 |
| 44 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28567377 |
| 45 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.25959422 |
| 46 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.25305725 |
| 47 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22779988 |
| 48 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.22485040 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.22071566 |
| 50 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.18872877 |
| 51 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.18627474 |
| 52 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.18619539 |
| 53 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.18247297 |
| 54 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.16135961 |
| 55 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.15489769 |
| 56 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.14867432 |
| 57 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.12425225 |
| 58 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.11303880 |
| 59 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.10396018 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10199333 |
| 61 | EWS_26573619_Chip-Seq_HEK293_Human | 1.09810865 |
| 62 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.09561324 |
| 63 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.08987737 |
| 64 | NCOR_22424771_ChIP-Seq_293T_Human | 1.08525256 |
| 65 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.08486373 |
| 66 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08086901 |
| 67 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.06988604 |
| 68 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.06686343 |
| 69 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.06365087 |
| 70 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.04510758 |
| 71 | FUS_26573619_Chip-Seq_HEK293_Human | 1.04437022 |
| 72 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.02926498 |
| 73 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.01022722 |
| 74 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.00588372 |
| 75 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.00147555 |
| 76 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99380981 |
| 77 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.99028049 |
| 78 | NFYA_21822215_ChIP-Seq_K562_Human | 0.98961922 |
| 79 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.98718869 |
| 80 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.98642355 |
| 81 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.98575133 |
| 82 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97624787 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.96321229 |
| 84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96008806 |
| 85 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95944893 |
| 86 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.95587690 |
| 87 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.95120920 |
| 88 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94765737 |
| 89 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.94380202 |
| 90 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.93751798 |
| 91 | GATA3_26560356_Chip-Seq_TH1_Human | 0.93067746 |
| 92 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.92670291 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.92014398 |
| 94 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.91936059 |
| 95 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.91785272 |
| 96 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91626367 |
| 97 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.91555498 |
| 98 | NFYB_21822215_ChIP-Seq_K562_Human | 0.90904298 |
| 99 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90368142 |
| 100 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88783830 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005360_urolithiasis | 6.40312955 |
| 2 | MP0008875_abnormal_xenobiotic_pharmacok | 3.35449099 |
| 3 | MP0003011_delayed_dark_adaptation | 2.98749364 |
| 4 | MP0010094_abnormal_chromosome_stability | 2.97948059 |
| 5 | MP0003172_abnormal_lysosome_physiology | 2.87095385 |
| 6 | MP0004215_abnormal_myocardial_fiber | 2.42737163 |
| 7 | MP0003763_abnormal_thymus_physiology | 2.34777314 |
| 8 | MP0008260_abnormal_autophagy | 2.34409423 |
| 9 | MP0003786_premature_aging | 2.30842507 |
| 10 | MP0004147_increased_porphyrin_level | 2.16610599 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 1.92188757 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 1.90253278 |
| 13 | MP0005671_abnormal_response_to | 1.89051618 |
| 14 | MP0008877_abnormal_DNA_methylation | 1.88432005 |
| 15 | MP0002876_abnormal_thyroid_physiology | 1.78390520 |
| 16 | MP0001984_abnormal_olfaction | 1.77775578 |
| 17 | MP0005379_endocrine/exocrine_gland_phen | 1.73080134 |
| 18 | MP0000013_abnormal_adipose_tissue | 1.71208920 |
| 19 | MP0002909_abnormal_adrenal_gland | 1.71143244 |
| 20 | MP0003111_abnormal_nucleus_morphology | 1.68394901 |
| 21 | MP0008058_abnormal_DNA_repair | 1.67740952 |
| 22 | MP0000538_abnormal_urinary_bladder | 1.67629144 |
| 23 | MP0000358_abnormal_cell_content/ | 1.66259688 |
| 24 | MP0006035_abnormal_mitochondrial_morpho | 1.61251719 |
| 25 | MP0003646_muscle_fatigue | 1.57291600 |
| 26 | MP0005167_abnormal_blood-brain_barrier | 1.48694402 |
| 27 | MP0001835_abnormal_antigen_presentation | 1.47227054 |
| 28 | MP0002102_abnormal_ear_morphology | 1.46805133 |
| 29 | MP0002733_abnormal_thermal_nociception | 1.45534626 |
| 30 | MP0006276_abnormal_autonomic_nervous | 1.38941102 |
| 31 | MP0005646_abnormal_pituitary_gland | 1.38479597 |
| 32 | MP0005253_abnormal_eye_physiology | 1.38114246 |
| 33 | MP0003186_abnormal_redox_activity | 1.34791350 |
| 34 | MP0001800_abnormal_humoral_immune | 1.32420714 |
| 35 | MP0000631_abnormal_neuroendocrine_gland | 1.30018054 |
| 36 | MP0005551_abnormal_eye_electrophysiolog | 1.28576535 |
| 37 | MP0008872_abnormal_physiological_respon | 1.25282884 |
| 38 | MP0005058_abnormal_lysosome_morphology | 1.22105055 |
| 39 | MP0001958_emphysema | 1.21584462 |
| 40 | MP0009764_decreased_sensitivity_to | 1.20319258 |
| 41 | MP0004043_abnormal_pH_regulation | 1.19600131 |
| 42 | MP0001501_abnormal_sleep_pattern | 1.17264530 |
| 43 | MP0001440_abnormal_grooming_behavior | 1.17226816 |
| 44 | MP0002210_abnormal_sex_determination | 1.12122742 |
| 45 | MP0003638_abnormal_response/metabolism_ | 1.09950396 |
| 46 | MP0003878_abnormal_ear_physiology | 1.09601127 |
| 47 | MP0005377_hearing/vestibular/ear_phenot | 1.09601127 |
| 48 | MP0008057_abnormal_DNA_replication | 1.07956250 |
| 49 | MP0001727_abnormal_embryo_implantation | 1.07534864 |
| 50 | MP0001529_abnormal_vocalization | 1.05568076 |
| 51 | MP0003938_abnormal_ear_development | 1.01967781 |
| 52 | MP0010386_abnormal_urinary_bladder | 1.01800270 |
| 53 | MP0002148_abnormal_hypersensitivity_rea | 1.01045417 |
| 54 | MP0000639_abnormal_adrenal_gland | 1.00657688 |
| 55 | MP0000230_abnormal_systemic_arterial | 0.98417342 |
| 56 | MP0001905_abnormal_dopamine_level | 0.97083808 |
| 57 | MP0003724_increased_susceptibility_to | 0.97055626 |
| 58 | MP0003937_abnormal_limbs/digits/tail_de | 0.96555723 |
| 59 | MP0004142_abnormal_muscle_tone | 0.95236437 |
| 60 | MP0002067_abnormal_sensory_capabilities | 0.90880902 |
| 61 | MP0001968_abnormal_touch/_nociception | 0.89698689 |
| 62 | MP0001929_abnormal_gametogenesis | 0.89506695 |
| 63 | MP0002006_tumorigenesis | 0.89329044 |
| 64 | MP0002163_abnormal_gland_morphology | 0.88971112 |
| 65 | MP0004145_abnormal_muscle_electrophysio | 0.87852833 |
| 66 | MP0002837_dystrophic_cardiac_calcinosis | 0.87509654 |
| 67 | MP0000015_abnormal_ear_pigmentation | 0.87234135 |
| 68 | MP0005410_abnormal_fertilization | 0.86883706 |
| 69 | MP0008789_abnormal_olfactory_epithelium | 0.86499118 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.84206328 |
| 71 | MP0002166_altered_tumor_susceptibility | 0.81933398 |
| 72 | MP0009384_cardiac_valve_regurgitation | 0.81214314 |
| 73 | MP0005319_abnormal_enzyme/_coenzyme | 0.80130725 |
| 74 | MP0001970_abnormal_pain_threshold | 0.79876066 |
| 75 | MP0002723_abnormal_immune_serum | 0.79063035 |
| 76 | MP0002452_abnormal_antigen_presenting | 0.76903841 |
| 77 | MP0000372_irregular_coat_pigmentation | 0.75420068 |
| 78 | MP0010329_abnormal_lipoprotein_level | 0.74662352 |
| 79 | MP0002638_abnormal_pupillary_reflex | 0.71970425 |
| 80 | MP0003136_yellow_coat_color | 0.71930858 |
| 81 | MP0000566_synostosis | 0.71382432 |
| 82 | MP0002736_abnormal_nociception_after | 0.69736323 |
| 83 | MP0002420_abnormal_adaptive_immunity | 0.68734050 |
| 84 | MP0000689_abnormal_spleen_morphology | 0.68366569 |
| 85 | MP0004924_abnormal_behavior | 0.68275333 |
| 86 | MP0005386_behavior/neurological_phenoty | 0.68275333 |
| 87 | MP0002277_abnormal_respiratory_mucosa | 0.67643863 |
| 88 | MP0005174_abnormal_tail_pigmentation | 0.67152587 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.66785886 |
| 90 | MP0002115_abnormal_skeleton_extremities | 0.66739992 |
| 91 | MP0008770_decreased_survivor_rate | 0.66581239 |
| 92 | MP0001270_distended_abdomen | 0.66457733 |
| 93 | MP0001819_abnormal_immune_cell | 0.65787044 |
| 94 | MP0000427_abnormal_hair_cycle | 0.64657260 |
| 95 | MP0003698_abnormal_male_reproductive | 0.63105292 |
| 96 | MP0008873_increased_physiological_sensi | 0.62902524 |
| 97 | MP0006138_congestive_heart_failure | 0.62734730 |
| 98 | MP0005000_abnormal_immune_tolerance | 0.62442632 |
| 99 | MP0005332_abnormal_amino_acid | 0.62163332 |
| 100 | MP0000653_abnormal_sex_gland | 0.59793425 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of cochlea (HP:0000375) | 5.38030041 |
| 2 | Poor speech (HP:0002465) | 4.65699339 |
| 3 | Abnormality of lateral ventricle (HP:0030047) | 4.59112992 |
| 4 | Conical tooth (HP:0000698) | 4.05560665 |
| 5 | Morphological abnormality of the inner ear (HP:0011390) | 3.98755848 |
| 6 | IgG deficiency (HP:0004315) | 3.93328300 |
| 7 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.87705711 |
| 8 | Absent hand (HP:0004050) | 3.47601218 |
| 9 | Tongue fasciculations (HP:0001308) | 3.44771981 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.39424359 |
| 11 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 3.32475381 |
| 12 | Tetraparesis (HP:0002273) | 3.13346097 |
| 13 | Flat capital femoral epiphysis (HP:0003370) | 3.10503440 |
| 14 | Hypoplastic iliac wings (HP:0002866) | 3.10270900 |
| 15 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.91874623 |
| 16 | Diastasis recti (HP:0001540) | 2.91821906 |
| 17 | Abnormality of the renal cortex (HP:0011035) | 2.88469863 |
| 18 | Muscle fibrillation (HP:0010546) | 2.87673928 |
| 19 | Chin dimple (HP:0010751) | 2.84871520 |
| 20 | Deep palmar crease (HP:0006191) | 2.83697611 |
| 21 | Progressive inability to walk (HP:0002505) | 2.83492187 |
| 22 | Calcaneovalgus deformity (HP:0001848) | 2.82437727 |
| 23 | Absent septum pellucidum (HP:0001331) | 2.79463283 |
| 24 | Absent epiphyses (HP:0010577) | 2.71962555 |
| 25 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.71962555 |
| 26 | Nephronophthisis (HP:0000090) | 2.71230455 |
| 27 | Congenital stationary night blindness (HP:0007642) | 2.66869325 |
| 28 | Deformed tarsal bones (HP:0008119) | 2.62914409 |
| 29 | Abnormality of the labia minora (HP:0012880) | 2.62299573 |
| 30 | Acute myeloid leukemia (HP:0004808) | 2.56211423 |
| 31 | Mitochondrial inheritance (HP:0001427) | 2.54890936 |
| 32 | Large eyes (HP:0001090) | 2.54833296 |
| 33 | 11 pairs of ribs (HP:0000878) | 2.54652590 |
| 34 | Carpal bone hypoplasia (HP:0001498) | 2.54555582 |
| 35 | Optic nerve hypoplasia (HP:0000609) | 2.53113331 |
| 36 | Type II lissencephaly (HP:0007260) | 2.49832335 |
| 37 | Severe muscular hypotonia (HP:0006829) | 2.46947922 |
| 38 | Sensory axonal neuropathy (HP:0003390) | 2.42235251 |
| 39 | Stomatitis (HP:0010280) | 2.39454445 |
| 40 | Abnormality of the fingertips (HP:0001211) | 2.39240340 |
| 41 | Severe visual impairment (HP:0001141) | 2.34926856 |
| 42 | Abnormality of the renal medulla (HP:0100957) | 2.30726201 |
| 43 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.29412595 |
| 44 | Spastic paraparesis (HP:0002313) | 2.25662622 |
| 45 | Type I transferrin isoform profile (HP:0003642) | 2.24714633 |
| 46 | Abnormality of the calcaneus (HP:0008364) | 2.24679304 |
| 47 | Hyperglycinuria (HP:0003108) | 2.24136741 |
| 48 | Pustule (HP:0200039) | 2.23782780 |
| 49 | Hepatic necrosis (HP:0002605) | 2.16870607 |
| 50 | Abnormality of the septum pellucidum (HP:0007375) | 2.16655973 |
| 51 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.13967748 |
| 52 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.13504974 |
| 53 | Cerebellar dysplasia (HP:0007033) | 2.13165438 |
| 54 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.12666912 |
| 55 | Abnormality of midbrain morphology (HP:0002418) | 2.11431250 |
| 56 | Molar tooth sign on MRI (HP:0002419) | 2.11431250 |
| 57 | Ketoacidosis (HP:0001993) | 2.09668464 |
| 58 | Renal cortical cysts (HP:0000803) | 2.09607243 |
| 59 | Medial flaring of the eyebrow (HP:0010747) | 2.08708739 |
| 60 | Small epiphyses (HP:0010585) | 2.08502336 |
| 61 | Mutism (HP:0002300) | 2.07787982 |
| 62 | Facial cleft (HP:0002006) | 2.07250121 |
| 63 | Stomach cancer (HP:0012126) | 2.06575272 |
| 64 | Type 2 muscle fiber atrophy (HP:0003554) | 2.02581135 |
| 65 | Vacuolated lymphocytes (HP:0001922) | 2.02297626 |
| 66 | Abolished electroretinogram (ERG) (HP:0000550) | 1.95602647 |
| 67 | Attenuation of retinal blood vessels (HP:0007843) | 1.92360866 |
| 68 | Overlapping toe (HP:0001845) | 1.90098129 |
| 69 | Hepatocellular necrosis (HP:0001404) | 1.89674069 |
| 70 | Abnormality of eosinophils (HP:0001879) | 1.89345567 |
| 71 | Erythema (HP:0010783) | 1.88129388 |
| 72 | True hermaphroditism (HP:0010459) | 1.87328202 |
| 73 | Tubulointerstitial fibrosis (HP:0005576) | 1.86839398 |
| 74 | Congenital sensorineural hearing impairment (HP:0008527) | 1.86524300 |
| 75 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.86186708 |
| 76 | Pancreatic cysts (HP:0001737) | 1.86105851 |
| 77 | Paraparesis (HP:0002385) | 1.82977460 |
| 78 | Muscle fiber atrophy (HP:0100295) | 1.82305079 |
| 79 | Inability to walk (HP:0002540) | 1.81875819 |
| 80 | Brittle hair (HP:0002299) | 1.80813276 |
| 81 | Hypoplasia of the pons (HP:0012110) | 1.80098214 |
| 82 | T lymphocytopenia (HP:0005403) | 1.78789827 |
| 83 | CNS hypomyelination (HP:0003429) | 1.78573125 |
| 84 | Generalized aminoaciduria (HP:0002909) | 1.78056816 |
| 85 | Broad distal phalanx of finger (HP:0009836) | 1.76059402 |
| 86 | Tracheomalacia (HP:0002779) | 1.75968183 |
| 87 | Hypergonadotropic hypogonadism (HP:0000815) | 1.75542338 |
| 88 | Agammaglobulinemia (HP:0004432) | 1.75216903 |
| 89 | Increased serum lactate (HP:0002151) | 1.73884206 |
| 90 | Opisthotonus (HP:0002179) | 1.73755211 |
| 91 | Panhypogammaglobulinemia (HP:0003139) | 1.73628532 |
| 92 | Abnormality of macular pigmentation (HP:0008002) | 1.72940406 |
| 93 | Abnormality of T cells (HP:0002843) | 1.72604836 |
| 94 | Menstrual irregularities (HP:0000858) | 1.70257821 |
| 95 | Disinhibition (HP:0000734) | 1.69005105 |
| 96 | Eosinophilia (HP:0001880) | 1.68831352 |
| 97 | Patellar aplasia (HP:0006443) | 1.66918825 |
| 98 | Congenital, generalized hypertrichosis (HP:0004540) | 1.65990536 |
| 99 | Vertebral arch anomaly (HP:0008438) | 1.65770864 |
| 100 | Gaze-evoked nystagmus (HP:0000640) | 1.65459301 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 7.69946683 |
| 2 | STK38L | 7.21680193 |
| 3 | ZAK | 3.54922156 |
| 4 | BLK | 3.20885972 |
| 5 | TXK | 3.12755624 |
| 6 | CDC7 | 2.91475466 |
| 7 | EIF2AK1 | 2.70102601 |
| 8 | WNK1 | 2.20882725 |
| 9 | STK38 | 1.97122537 |
| 10 | BMPR1B | 1.86738449 |
| 11 | PHKG1 | 1.85652884 |
| 12 | PHKG2 | 1.85652884 |
| 13 | MAP4K2 | 1.68369990 |
| 14 | ZAP70 | 1.63527970 |
| 15 | KIT | 1.54193711 |
| 16 | PINK1 | 1.48183620 |
| 17 | MAP4K1 | 1.41798550 |
| 18 | FRK | 1.41484421 |
| 19 | MST4 | 1.29000558 |
| 20 | TLK1 | 1.21748955 |
| 21 | EPHA2 | 1.16537437 |
| 22 | ADRBK2 | 1.14184754 |
| 23 | SYK | 1.08450698 |
| 24 | FES | 1.06170641 |
| 25 | BRSK2 | 0.99916455 |
| 26 | CSNK1G3 | 0.96814579 |
| 27 | TESK2 | 0.95500120 |
| 28 | GRK1 | 0.94738280 |
| 29 | NUAK1 | 0.94211851 |
| 30 | CSNK1A1L | 0.88582996 |
| 31 | CSF1R | 0.87743017 |
| 32 | CDK8 | 0.86893007 |
| 33 | CSNK1G2 | 0.86800979 |
| 34 | KDR | 0.86386922 |
| 35 | TGFBR1 | 0.86377249 |
| 36 | CDK19 | 0.83985410 |
| 37 | MAPKAPK5 | 0.83745838 |
| 38 | IKBKB | 0.81558950 |
| 39 | VRK1 | 0.80714342 |
| 40 | MKNK1 | 0.78349870 |
| 41 | NEK1 | 0.77909800 |
| 42 | BCKDK | 0.76767572 |
| 43 | CSNK1G1 | 0.75790481 |
| 44 | MAPKAPK3 | 0.75190713 |
| 45 | LYN | 0.74813116 |
| 46 | IKBKE | 0.72535916 |
| 47 | ITK | 0.72398727 |
| 48 | TAF1 | 0.71372873 |
| 49 | TIE1 | 0.69818761 |
| 50 | CDK3 | 0.65522605 |
| 51 | CHEK2 | 0.64209626 |
| 52 | CSNK1D | 0.63814487 |
| 53 | JAK3 | 0.60404177 |
| 54 | EIF2AK3 | 0.56547239 |
| 55 | PTK2B | 0.50545982 |
| 56 | TNK2 | 0.50197597 |
| 57 | MARK3 | 0.50186040 |
| 58 | LIMK1 | 0.46759713 |
| 59 | PAK6 | 0.46637087 |
| 60 | TEC | 0.45566403 |
| 61 | PLK3 | 0.44747152 |
| 62 | FLT3 | 0.44427347 |
| 63 | TESK1 | 0.43537597 |
| 64 | PLK2 | 0.40990679 |
| 65 | FGFR2 | 0.40874005 |
| 66 | WNK4 | 0.40219429 |
| 67 | EIF2AK2 | 0.39325804 |
| 68 | GRK5 | 0.38942932 |
| 69 | MAPK11 | 0.37920846 |
| 70 | DYRK2 | 0.37894043 |
| 71 | IGF1R | 0.37809363 |
| 72 | IRAK3 | 0.37408231 |
| 73 | NME1 | 0.37221960 |
| 74 | RPS6KA5 | 0.36343553 |
| 75 | STK39 | 0.34894236 |
| 76 | PRKG2 | 0.34387911 |
| 77 | INSRR | 0.34110788 |
| 78 | MAP2K2 | 0.33807917 |
| 79 | MAP3K14 | 0.30574517 |
| 80 | MAPK9 | 0.29899912 |
| 81 | PLK1 | 0.29463338 |
| 82 | CASK | 0.29426086 |
| 83 | MAP3K4 | 0.28293267 |
| 84 | LCK | 0.27851522 |
| 85 | OXSR1 | 0.27802212 |
| 86 | PRKG1 | 0.27354294 |
| 87 | FYN | 0.25368149 |
| 88 | PRKACB | 0.25048230 |
| 89 | CSNK2A1 | 0.23575296 |
| 90 | ATR | 0.22944623 |
| 91 | VRK2 | 0.21973253 |
| 92 | JAK2 | 0.21689583 |
| 93 | OBSCN | 0.20885674 |
| 94 | ATM | 0.20817479 |
| 95 | ADRBK1 | 0.20530540 |
| 96 | EPHA4 | 0.20347630 |
| 97 | NEK6 | 0.19668584 |
| 98 | ABL1 | 0.19520688 |
| 99 | MAPK8 | 0.19285150 |
| 100 | MAPK13 | 0.19278696 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Caffeine metabolism_Homo sapiens_hsa00232 | 6.61441820 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 3.46605512 |
| 3 | Tryptophan metabolism_Homo sapiens_hsa00380 | 3.34484464 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.18482152 |
| 5 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.41705248 |
| 6 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.36982553 |
| 7 | Phototransduction_Homo sapiens_hsa04744 | 2.31602750 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.26621695 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.88613854 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.85902149 |
| 11 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.84990451 |
| 12 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.75435432 |
| 13 | Circadian rhythm_Homo sapiens_hsa04710 | 1.73054132 |
| 14 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.71271854 |
| 15 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.71106262 |
| 16 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.60795342 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.49211416 |
| 18 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.40507583 |
| 19 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.40136952 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.38386282 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.37317355 |
| 22 | Retinol metabolism_Homo sapiens_hsa00830 | 1.36957513 |
| 23 | Sulfur relay system_Homo sapiens_hsa04122 | 1.29290927 |
| 24 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.27706456 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.24568193 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23573094 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.22521076 |
| 28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.22224558 |
| 29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.21922565 |
| 30 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.21836858 |
| 31 | Olfactory transduction_Homo sapiens_hsa04740 | 1.15699429 |
| 32 | Morphine addiction_Homo sapiens_hsa05032 | 1.13965342 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.13886344 |
| 34 | Parkinsons disease_Homo sapiens_hsa05012 | 1.12431620 |
| 35 | RNA degradation_Homo sapiens_hsa03018 | 1.11085782 |
| 36 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05497126 |
| 37 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.04238051 |
| 38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.04088808 |
| 39 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.02293436 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.01540507 |
| 41 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.01521953 |
| 42 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.01289377 |
| 43 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.99804086 |
| 44 | Allograft rejection_Homo sapiens_hsa05330 | 0.99515569 |
| 45 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.97364285 |
| 46 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.97228217 |
| 47 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.96215116 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.96199035 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.95756464 |
| 50 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.93887695 |
| 51 | Homologous recombination_Homo sapiens_hsa03440 | 0.93680857 |
| 52 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.93497116 |
| 53 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.92930557 |
| 54 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.92899056 |
| 55 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.90679925 |
| 56 | RNA polymerase_Homo sapiens_hsa03020 | 0.85977598 |
| 57 | Lysine degradation_Homo sapiens_hsa00310 | 0.85775814 |
| 58 | Shigellosis_Homo sapiens_hsa05131 | 0.84379157 |
| 59 | Purine metabolism_Homo sapiens_hsa00230 | 0.77940401 |
| 60 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68952974 |
| 61 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.67341492 |
| 62 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.67158995 |
| 63 | Huntingtons disease_Homo sapiens_hsa05016 | 0.66978986 |
| 64 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.65275071 |
| 65 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.64319541 |
| 66 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.63383580 |
| 67 | Alzheimers disease_Homo sapiens_hsa05010 | 0.62309100 |
| 68 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.62012869 |
| 69 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60515819 |
| 70 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.60137674 |
| 71 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.60042524 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.59111448 |
| 73 | Spliceosome_Homo sapiens_hsa03040 | 0.57352730 |
| 74 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.56690314 |
| 75 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.55214056 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54901208 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53882603 |
| 78 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.52096951 |
| 79 | Salivary secretion_Homo sapiens_hsa04970 | 0.49678024 |
| 80 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.49393399 |
| 81 | Base excision repair_Homo sapiens_hsa03410 | 0.47493056 |
| 82 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.45811859 |
| 83 | ABC transporters_Homo sapiens_hsa02010 | 0.45747001 |
| 84 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.44404680 |
| 85 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.43185703 |
| 86 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.43026237 |
| 87 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.42610613 |
| 88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.41846534 |
| 89 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.39105148 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.39041885 |
| 91 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.36523470 |
| 92 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.36231474 |
| 93 | Lysosome_Homo sapiens_hsa04142 | 0.35009958 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.33666968 |
| 95 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.31424910 |
| 96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.30283891 |
| 97 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.29663905 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28353144 |
| 99 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.25456252 |
| 100 | Taste transduction_Homo sapiens_hsa04742 | 0.25248158 |

