

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.21958957 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.78169602 |
| 3 | rRNA modification (GO:0000154) | 5.85877991 |
| 4 | respiratory chain complex IV assembly (GO:0008535) | 5.76197025 |
| 5 | cytidine deamination (GO:0009972) | 5.43984116 |
| 6 | cytidine metabolic process (GO:0046087) | 5.43984116 |
| 7 | cytidine catabolic process (GO:0006216) | 5.43984116 |
| 8 | positive regulation of T cell differentiation in thymus (GO:0033089) | 5.05049794 |
| 9 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.99480331 |
| 10 | regulation of memory T cell differentiation (GO:0043380) | 4.94283103 |
| 11 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.89101958 |
| 12 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.89101958 |
| 13 | rRNA methylation (GO:0031167) | 4.77135443 |
| 14 | maturation of 5.8S rRNA (GO:0000460) | 4.57568942 |
| 15 | cytochrome complex assembly (GO:0017004) | 4.55280185 |
| 16 | preassembly of GPI anchor in ER membrane (GO:0016254) | 4.45838302 |
| 17 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.43446808 |
| 18 | DNA catabolic process, exonucleolytic (GO:0000738) | 4.42906941 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.32121845 |
| 20 | pseudouridine synthesis (GO:0001522) | 4.25493832 |
| 21 | positive regulation of isotype switching (GO:0045830) | 4.13434082 |
| 22 | regulation of regulatory T cell differentiation (GO:0045589) | 4.12682664 |
| 23 | short-chain fatty acid metabolic process (GO:0046459) | 4.09521984 |
| 24 | positive regulation of DNA recombination (GO:0045911) | 3.97027142 |
| 25 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.94544299 |
| 26 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.94033292 |
| 27 | DNA double-strand break processing (GO:0000729) | 3.89512881 |
| 28 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.88021473 |
| 29 | ATP synthesis coupled proton transport (GO:0015986) | 3.88021473 |
| 30 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.87958430 |
| 31 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.82403087 |
| 32 | cellular response to interferon-beta (GO:0035458) | 3.78607113 |
| 33 | GPI anchor metabolic process (GO:0006505) | 3.60283900 |
| 34 | regulation of immunoglobulin secretion (GO:0051023) | 3.58873744 |
| 35 | negative regulation of mRNA processing (GO:0050686) | 3.57478671 |
| 36 | platelet dense granule organization (GO:0060155) | 3.55338646 |
| 37 | negative regulation of RNA splicing (GO:0033119) | 3.53836247 |
| 38 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.41048793 |
| 39 | regulation of cilium movement (GO:0003352) | 3.38709947 |
| 40 | positive regulation of T cell cytokine production (GO:0002726) | 3.38709238 |
| 41 | establishment of integrated proviral latency (GO:0075713) | 3.32155159 |
| 42 | resolution of meiotic recombination intermediates (GO:0000712) | 3.31146943 |
| 43 | protein polyglutamylation (GO:0018095) | 3.29089302 |
| 44 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.26328116 |
| 45 | proteasome assembly (GO:0043248) | 3.25852324 |
| 46 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.21426098 |
| 47 | NADH dehydrogenase complex assembly (GO:0010257) | 3.21426098 |
| 48 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.21426098 |
| 49 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.21423324 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.18781347 |
| 51 | GPI anchor biosynthetic process (GO:0006506) | 3.15847172 |
| 52 | protein complex biogenesis (GO:0070271) | 3.14427820 |
| 53 | autophagic vacuole fusion (GO:0000046) | 3.11437823 |
| 54 | response to pheromone (GO:0019236) | 3.10982349 |
| 55 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.09221999 |
| 56 | adaptation of signaling pathway (GO:0023058) | 3.09154253 |
| 57 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.03031965 |
| 58 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.03031965 |
| 59 | amino acid activation (GO:0043038) | 3.00197652 |
| 60 | tRNA aminoacylation (GO:0043039) | 3.00197652 |
| 61 | tRNA aminoacylation for protein translation (GO:0006418) | 2.99392874 |
| 62 | regulation of translational elongation (GO:0006448) | 2.97890519 |
| 63 | glycine transport (GO:0015816) | 2.94934015 |
| 64 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.91782934 |
| 65 | positive regulation of granulocyte differentiation (GO:0030854) | 2.89664888 |
| 66 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 2.87969988 |
| 67 | DNA demethylation (GO:0080111) | 2.87699608 |
| 68 | response to interferon-beta (GO:0035456) | 2.87339691 |
| 69 | protein neddylation (GO:0045116) | 2.86159292 |
| 70 | negative regulation of interleukin-17 production (GO:0032700) | 2.85262952 |
| 71 | kidney morphogenesis (GO:0060993) | 2.81327878 |
| 72 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.80125037 |
| 73 | negative regulation of mRNA metabolic process (GO:1903312) | 2.78502936 |
| 74 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.78256835 |
| 75 | isotype switching (GO:0045190) | 2.78256835 |
| 76 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.78256835 |
| 77 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.78132485 |
| 78 | regulation of mitochondrial translation (GO:0070129) | 2.77494294 |
| 79 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.77123044 |
| 80 | proline transport (GO:0015824) | 2.77118995 |
| 81 | artery smooth muscle contraction (GO:0014824) | 2.76831404 |
| 82 | response to gravity (GO:0009629) | 2.75527147 |
| 83 | positive regulation of defense response to virus by host (GO:0002230) | 2.73556203 |
| 84 | mismatch repair (GO:0006298) | 2.72616779 |
| 85 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.71334497 |
| 86 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.70786212 |
| 87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.70786212 |
| 88 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.69593602 |
| 89 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.69593602 |
| 90 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.69593602 |
| 91 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.69272715 |
| 92 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.68872809 |
| 93 | negative regulation of cell killing (GO:0031342) | 2.65784939 |
| 94 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.65784939 |
| 95 | protein K6-linked ubiquitination (GO:0085020) | 2.65115174 |
| 96 | ER overload response (GO:0006983) | 2.64175059 |
| 97 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.63533427 |
| 98 | positive regulation of growth hormone secretion (GO:0060124) | 2.61893662 |
| 99 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.61099159 |
| 100 | negative regulation of telomere maintenance (GO:0032205) | 2.60044873 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.68442514 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.62632947 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82420455 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.53182414 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.13497339 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.93118002 |
| 7 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.90460297 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.88054065 |
| 9 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.72852192 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.69320866 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.68206259 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.65711226 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.63876754 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.55027535 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.54049279 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.46885165 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.43166346 |
| 18 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.28736504 |
| 19 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.15191694 |
| 20 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.08286919 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.02268946 |
| 22 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.98315851 |
| 23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.96502305 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.95566892 |
| 25 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.95363818 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.92355209 |
| 27 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.88011575 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.87912497 |
| 29 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.73277643 |
| 30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.71116762 |
| 31 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.70761202 |
| 32 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.70646013 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.53392516 |
| 34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.51534096 |
| 35 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.49086192 |
| 36 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.47826084 |
| 37 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.47013619 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.46781563 |
| 39 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.46720888 |
| 40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.45042804 |
| 41 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.44514101 |
| 42 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.43334119 |
| 43 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.42506515 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.41840192 |
| 45 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.40758883 |
| 46 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.40253847 |
| 47 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.37644103 |
| 48 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.37456424 |
| 49 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.35556985 |
| 50 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.35199204 |
| 51 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.35188835 |
| 52 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.35188835 |
| 53 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.33980938 |
| 54 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.33348122 |
| 55 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.33043297 |
| 56 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.32693297 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.31684484 |
| 58 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22531443 |
| 59 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.20545002 |
| 60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.19117243 |
| 61 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.16444008 |
| 62 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15443418 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15420748 |
| 64 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.11240709 |
| 65 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.10345840 |
| 66 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.10345840 |
| 67 | P300_19829295_ChIP-Seq_ESCs_Human | 1.08630987 |
| 68 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.08342827 |
| 69 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.07867806 |
| 70 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.07728130 |
| 71 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07560103 |
| 72 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04424351 |
| 73 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04424351 |
| 74 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.03989530 |
| 75 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.03358836 |
| 76 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.03244662 |
| 77 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.02526172 |
| 78 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.01955468 |
| 79 | GATA3_26560356_Chip-Seq_TH2_Human | 1.01379808 |
| 80 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.01001904 |
| 81 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.98865461 |
| 82 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97340670 |
| 83 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96608649 |
| 84 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96244583 |
| 85 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.95165480 |
| 86 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.94697479 |
| 87 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.94140955 |
| 88 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.93742068 |
| 89 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.93716365 |
| 90 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93546246 |
| 91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.93384019 |
| 92 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93349287 |
| 93 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.93204951 |
| 94 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.91565662 |
| 95 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.89918955 |
| 96 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.88124858 |
| 97 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.88075747 |
| 98 | AR_20517297_ChIP-Seq_VCAP_Human | 0.87926015 |
| 99 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.87785750 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 0.85062355 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006054_spinal_hemorrhage | 5.22964616 |
| 2 | MP0004147_increased_porphyrin_level | 4.11525148 |
| 3 | MP0003806_abnormal_nucleotide_metabolis | 4.06439384 |
| 4 | MP0001853_heart_inflammation | 3.23146291 |
| 5 | MP0002102_abnormal_ear_morphology | 2.83588627 |
| 6 | MP0005084_abnormal_gallbladder_morpholo | 2.75693731 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.74500500 |
| 8 | MP0008058_abnormal_DNA_repair | 2.62506469 |
| 9 | MP0002254_reproductive_system_inflammat | 2.54700876 |
| 10 | MP0005671_abnormal_response_to | 2.27969493 |
| 11 | MP0008789_abnormal_olfactory_epithelium | 2.13153794 |
| 12 | MP0003646_muscle_fatigue | 2.11650731 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.06927474 |
| 14 | MP0001727_abnormal_embryo_implantation | 1.95045168 |
| 15 | MP0005646_abnormal_pituitary_gland | 1.94857602 |
| 16 | MP0004381_abnormal_hair_follicle | 1.94513943 |
| 17 | MP0005167_abnormal_blood-brain_barrier | 1.87806662 |
| 18 | MP0005636_abnormal_mineral_homeostasis | 1.77574113 |
| 19 | MP0008057_abnormal_DNA_replication | 1.74318338 |
| 20 | MP0003186_abnormal_redox_activity | 1.73570526 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.68243574 |
| 22 | MP0003693_abnormal_embryo_hatching | 1.65066439 |
| 23 | MP0001529_abnormal_vocalization | 1.62253126 |
| 24 | MP0005360_urolithiasis | 1.62134757 |
| 25 | MP0006072_abnormal_retinal_apoptosis | 1.61845709 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.60206859 |
| 27 | MP0009780_abnormal_chondrocyte_physiolo | 1.55588464 |
| 28 | MP0002148_abnormal_hypersensitivity_rea | 1.53931813 |
| 29 | MP0002736_abnormal_nociception_after | 1.53354889 |
| 30 | MP0010094_abnormal_chromosome_stability | 1.52237041 |
| 31 | MP0003718_maternal_effect | 1.51890119 |
| 32 | MP0005085_abnormal_gallbladder_physiolo | 1.49695575 |
| 33 | MP0006036_abnormal_mitochondrial_physio | 1.49218976 |
| 34 | MP0002127_abnormal_cardiovascular_syste | 1.45523628 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.44729482 |
| 36 | MP0002938_white_spotting | 1.43612891 |
| 37 | MP0004957_abnormal_blastocyst_morpholog | 1.40924286 |
| 38 | MP0005253_abnormal_eye_physiology | 1.38576743 |
| 39 | MP0008007_abnormal_cellular_replicative | 1.38188000 |
| 40 | MP0003786_premature_aging | 1.37487109 |
| 41 | MP0003283_abnormal_digestive_organ | 1.35075410 |
| 42 | MP0002396_abnormal_hematopoietic_system | 1.31802205 |
| 43 | MP0005394_taste/olfaction_phenotype | 1.26450117 |
| 44 | MP0005499_abnormal_olfactory_system | 1.26450117 |
| 45 | MP0003077_abnormal_cell_cycle | 1.23992013 |
| 46 | MP0000516_abnormal_urinary_system | 1.22454571 |
| 47 | MP0005367_renal/urinary_system_phenotyp | 1.22454571 |
| 48 | MP0000689_abnormal_spleen_morphology | 1.21742594 |
| 49 | MP0001542_abnormal_bone_strength | 1.21334926 |
| 50 | MP0000372_irregular_coat_pigmentation | 1.19317338 |
| 51 | MP0006035_abnormal_mitochondrial_morpho | 1.18342623 |
| 52 | MP0005464_abnormal_platelet_physiology | 1.12626422 |
| 53 | MP0000639_abnormal_adrenal_gland | 1.10732654 |
| 54 | MP0005000_abnormal_immune_tolerance | 1.09714304 |
| 55 | MP0001968_abnormal_touch/_nociception | 1.06493025 |
| 56 | MP0003763_abnormal_thymus_physiology | 1.05415711 |
| 57 | MP0009785_altered_susceptibility_to | 1.04418525 |
| 58 | MP0003252_abnormal_bile_duct | 1.04374378 |
| 59 | MP0002398_abnormal_bone_marrow | 1.01084087 |
| 60 | MP0003866_abnormal_defecation | 1.00164133 |
| 61 | MP0001764_abnormal_homeostasis | 0.99921288 |
| 62 | MP0004019_abnormal_vitamin_homeostasis | 0.99841456 |
| 63 | MP0004145_abnormal_muscle_electrophysio | 0.99680817 |
| 64 | MP0001765_abnormal_ion_homeostasis | 0.99626528 |
| 65 | MP0002723_abnormal_immune_serum | 0.99018735 |
| 66 | MP0005332_abnormal_amino_acid | 0.98418357 |
| 67 | MP0001486_abnormal_startle_reflex | 0.98274139 |
| 68 | MP0010329_abnormal_lipoprotein_level | 0.97959137 |
| 69 | MP0002452_abnormal_antigen_presenting | 0.96884214 |
| 70 | MP0000015_abnormal_ear_pigmentation | 0.95482096 |
| 71 | MP0001819_abnormal_immune_cell | 0.94476130 |
| 72 | MP0001485_abnormal_pinna_reflex | 0.93262634 |
| 73 | MP0001919_abnormal_reproductive_system | 0.92596562 |
| 74 | MP0002420_abnormal_adaptive_immunity | 0.89774379 |
| 75 | MP0004742_abnormal_vestibular_system | 0.88266696 |
| 76 | MP0004947_skin_inflammation | 0.87151860 |
| 77 | MP0001800_abnormal_humoral_immune | 0.86817469 |
| 78 | MP0009697_abnormal_copulation | 0.85711879 |
| 79 | MP0005330_cardiomyopathy | 0.85198190 |
| 80 | MP0000013_abnormal_adipose_tissue | 0.84377315 |
| 81 | MP0004885_abnormal_endolymph | 0.84034663 |
| 82 | MP0000358_abnormal_cell_content/ | 0.82671943 |
| 83 | MP0001119_abnormal_female_reproductive | 0.82600561 |
| 84 | MP0005410_abnormal_fertilization | 0.82301192 |
| 85 | MP0002019_abnormal_tumor_incidence | 0.82212034 |
| 86 | MP0001984_abnormal_olfaction | 0.80887030 |
| 87 | MP0008872_abnormal_physiological_respon | 0.77601713 |
| 88 | MP0002693_abnormal_pancreas_physiology | 0.77550194 |
| 89 | MP0003111_abnormal_nucleus_morphology | 0.77133323 |
| 90 | MP0005266_abnormal_metabolism | 0.76935238 |
| 91 | MP0006292_abnormal_olfactory_placode | 0.75909871 |
| 92 | MP0000685_abnormal_immune_system | 0.75392129 |
| 93 | MP0001790_abnormal_immune_system | 0.75071610 |
| 94 | MP0005387_immune_system_phenotype | 0.75071610 |
| 95 | MP0000703_abnormal_thymus_morphology | 0.74866417 |
| 96 | MP0003195_calcinosis | 0.74759811 |
| 97 | MP0008873_increased_physiological_sensi | 0.73414853 |
| 98 | MP0009053_abnormal_anal_canal | 0.73106947 |
| 99 | MP0005645_abnormal_hypothalamus_physiol | 0.70996934 |
| 100 | MP0001873_stomach_inflammation | 0.69687969 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Methylmalonic acidemia (HP:0002912) | 6.88108764 |
| 2 | Methylmalonic aciduria (HP:0012120) | 4.92535424 |
| 3 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 4.54591190 |
| 4 | Abnormality of vitamin B metabolism (HP:0004340) | 4.44514126 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.11235842 |
| 6 | Petechiae (HP:0000967) | 3.86782739 |
| 7 | Aplastic anemia (HP:0001915) | 3.82546221 |
| 8 | Meckel diverticulum (HP:0002245) | 3.66885583 |
| 9 | Abnormality of the ileum (HP:0001549) | 3.49163353 |
| 10 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.46695034 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.39022925 |
| 12 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.35894395 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.32798656 |
| 14 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.25748429 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 3.25281428 |
| 16 | Abnormality of vitamin metabolism (HP:0100508) | 3.23200391 |
| 17 | Increased serum lactate (HP:0002151) | 3.22318983 |
| 18 | Increased CSF lactate (HP:0002490) | 3.18713003 |
| 19 | Mitochondrial inheritance (HP:0001427) | 3.18145015 |
| 20 | Hepatic necrosis (HP:0002605) | 3.13603742 |
| 21 | 3-Methylglutaconic aciduria (HP:0003535) | 3.12619982 |
| 22 | Renal cortical cysts (HP:0000803) | 3.11259173 |
| 23 | Abnormality of the preputium (HP:0100587) | 3.10717579 |
| 24 | Acute necrotizing encephalopathy (HP:0006965) | 3.06191931 |
| 25 | Acute encephalopathy (HP:0006846) | 3.02788508 |
| 26 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.00190545 |
| 27 | Abnormality of alanine metabolism (HP:0010916) | 3.00190545 |
| 28 | Hyperalaninemia (HP:0003348) | 3.00190545 |
| 29 | Abnormality of the carotid arteries (HP:0005344) | 2.94878154 |
| 30 | Clubbing of toes (HP:0100760) | 2.90581567 |
| 31 | Poor head control (HP:0002421) | 2.79633091 |
| 32 | Pigmentary retinal degeneration (HP:0001146) | 2.77798346 |
| 33 | Hyperglycinuria (HP:0003108) | 2.75256576 |
| 34 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.74629365 |
| 35 | Hypoplasia of the fovea (HP:0007750) | 2.74629365 |
| 36 | Renal Fanconi syndrome (HP:0001994) | 2.71564231 |
| 37 | Abnormality of chromosome stability (HP:0003220) | 2.71368658 |
| 38 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.69617776 |
| 39 | Severe combined immunodeficiency (HP:0004430) | 2.67642153 |
| 40 | Dicarboxylic aciduria (HP:0003215) | 2.59182625 |
| 41 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.59182625 |
| 42 | Abnormality of glycine metabolism (HP:0010895) | 2.56583316 |
| 43 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.56583316 |
| 44 | IgG deficiency (HP:0004315) | 2.56164291 |
| 45 | Progressive macrocephaly (HP:0004481) | 2.53945139 |
| 46 | Pancytopenia (HP:0001876) | 2.53732022 |
| 47 | Facial diplegia (HP:0001349) | 2.52597512 |
| 48 | Prolonged neonatal jaundice (HP:0006579) | 2.49035030 |
| 49 | Hemiparesis (HP:0001269) | 2.48447460 |
| 50 | Duodenal stenosis (HP:0100867) | 2.47270920 |
| 51 | Small intestinal stenosis (HP:0012848) | 2.47270920 |
| 52 | Lactic acidosis (HP:0003128) | 2.45371411 |
| 53 | Cleft eyelid (HP:0000625) | 2.45217794 |
| 54 | Abnormal number of erythroid precursors (HP:0012131) | 2.43756065 |
| 55 | Testicular atrophy (HP:0000029) | 2.38576181 |
| 56 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.37659116 |
| 57 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.37659116 |
| 58 | Curly hair (HP:0002212) | 2.31122092 |
| 59 | B lymphocytopenia (HP:0010976) | 2.25874939 |
| 60 | Combined immunodeficiency (HP:0005387) | 2.25210537 |
| 61 | Leukopenia (HP:0001882) | 2.22755576 |
| 62 | Abnormality of the fovea (HP:0000493) | 2.22479823 |
| 63 | Progressive microcephaly (HP:0000253) | 2.20916688 |
| 64 | Abnormality of the duodenum (HP:0002246) | 2.20328377 |
| 65 | Thyroiditis (HP:0100646) | 2.17049356 |
| 66 | Septate vagina (HP:0001153) | 2.16512214 |
| 67 | Hyperglycinemia (HP:0002154) | 2.12403729 |
| 68 | Increased intramyocellular lipid droplets (HP:0012240) | 2.11927869 |
| 69 | Myelodysplasia (HP:0002863) | 2.11915139 |
| 70 | Cerebral edema (HP:0002181) | 2.09330887 |
| 71 | Pancreatic cysts (HP:0001737) | 2.08388528 |
| 72 | Abnormality of the renal cortex (HP:0011035) | 2.05841007 |
| 73 | Oral leukoplakia (HP:0002745) | 2.02681323 |
| 74 | Abnormality of serum amino acid levels (HP:0003112) | 2.02523660 |
| 75 | Prolonged bleeding time (HP:0003010) | 1.99469104 |
| 76 | Micronodular cirrhosis (HP:0001413) | 1.99254256 |
| 77 | Abnormality of B cell number (HP:0010975) | 1.93031244 |
| 78 | Generalized aminoaciduria (HP:0002909) | 1.89126744 |
| 79 | Acute hepatic failure (HP:0006554) | 1.88486041 |
| 80 | Cerebral palsy (HP:0100021) | 1.85610727 |
| 81 | Elfin facies (HP:0004428) | 1.84636866 |
| 82 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.83959191 |
| 83 | Exertional dyspnea (HP:0002875) | 1.83102792 |
| 84 | Neutropenia (HP:0001875) | 1.82469766 |
| 85 | Medial flaring of the eyebrow (HP:0010747) | 1.82329439 |
| 86 | Pendular nystagmus (HP:0012043) | 1.81358571 |
| 87 | Hydroxyprolinuria (HP:0003080) | 1.79871153 |
| 88 | Abnormality of proline metabolism (HP:0010907) | 1.79871153 |
| 89 | Purpura (HP:0000979) | 1.79793254 |
| 90 | Abnormality of the renal collecting system (HP:0004742) | 1.79367352 |
| 91 | Porencephaly (HP:0002132) | 1.79175561 |
| 92 | Increased muscle lipid content (HP:0009058) | 1.78978202 |
| 93 | High anterior hairline (HP:0009890) | 1.78022080 |
| 94 | Progressive inability to walk (HP:0002505) | 1.77863713 |
| 95 | Chromsome breakage (HP:0040012) | 1.77381964 |
| 96 | Respiratory failure (HP:0002878) | 1.76562302 |
| 97 | Abnormality of urine glucose concentration (HP:0011016) | 1.75773144 |
| 98 | Glycosuria (HP:0003076) | 1.75773144 |
| 99 | Duplicated collecting system (HP:0000081) | 1.73618565 |
| 100 | Congenital stationary night blindness (HP:0007642) | 1.73120810 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 5.76046234 |
| 2 | MST4 | 4.44984482 |
| 3 | TXK | 3.20168886 |
| 4 | BMPR1B | 2.67378842 |
| 5 | NUAK1 | 2.64426762 |
| 6 | MAP4K1 | 2.55323485 |
| 7 | TESK2 | 2.52453303 |
| 8 | KDR | 2.45895882 |
| 9 | TAF1 | 2.37845931 |
| 10 | MAP3K12 | 2.26896451 |
| 11 | STK10 | 2.04346791 |
| 12 | TLK1 | 1.94616843 |
| 13 | BUB1 | 1.92277072 |
| 14 | EIF2AK1 | 1.90719209 |
| 15 | VRK1 | 1.83894303 |
| 16 | EIF2AK3 | 1.81794331 |
| 17 | EIF2AK2 | 1.80471901 |
| 18 | SRPK1 | 1.73231257 |
| 19 | PBK | 1.73145506 |
| 20 | GRK1 | 1.71540682 |
| 21 | GRK7 | 1.67237329 |
| 22 | TIE1 | 1.62373921 |
| 23 | NEK1 | 1.50117345 |
| 24 | RPS6KA4 | 1.45474851 |
| 25 | GRK5 | 1.36567953 |
| 26 | TGFBR2 | 1.34763969 |
| 27 | DAPK1 | 1.32052385 |
| 28 | TGFBR1 | 1.27130488 |
| 29 | CSNK1G2 | 1.26259338 |
| 30 | WNK3 | 1.22302952 |
| 31 | PDK2 | 1.18096773 |
| 32 | MKNK2 | 1.16018681 |
| 33 | ADRBK2 | 1.11222300 |
| 34 | NME1 | 1.10061339 |
| 35 | MKNK1 | 1.08612673 |
| 36 | CSNK1G3 | 1.07928626 |
| 37 | DYRK2 | 1.03586133 |
| 38 | ATR | 1.02308324 |
| 39 | IRAK1 | 1.02216457 |
| 40 | TNK2 | 1.01646514 |
| 41 | KIT | 0.93454969 |
| 42 | TRIM28 | 0.90893505 |
| 43 | IKBKB | 0.89543052 |
| 44 | DAPK2 | 0.87229832 |
| 45 | CSNK1G1 | 0.85147318 |
| 46 | TNIK | 0.84337838 |
| 47 | MAP3K5 | 0.82253688 |
| 48 | PLK3 | 0.81488478 |
| 49 | CDC7 | 0.81088535 |
| 50 | PAK3 | 0.80837062 |
| 51 | TEC | 0.78672535 |
| 52 | CSNK1A1L | 0.76341299 |
| 53 | CCNB1 | 0.71818445 |
| 54 | STK16 | 0.70585572 |
| 55 | PIM2 | 0.70543214 |
| 56 | PLK4 | 0.69685923 |
| 57 | CDK8 | 0.69218854 |
| 58 | TSSK6 | 0.69003936 |
| 59 | STK4 | 0.68028135 |
| 60 | TESK1 | 0.67424995 |
| 61 | STK38L | 0.67007884 |
| 62 | INSRR | 0.61235462 |
| 63 | MAPK13 | 0.60669152 |
| 64 | FRK | 0.59515218 |
| 65 | WEE1 | 0.58197076 |
| 66 | ACVR1B | 0.57808922 |
| 67 | AKT3 | 0.57685240 |
| 68 | DAPK3 | 0.57617996 |
| 69 | MYLK | 0.56775398 |
| 70 | AURKB | 0.56079541 |
| 71 | JAK1 | 0.55369569 |
| 72 | MELK | 0.53394601 |
| 73 | MOS | 0.53092093 |
| 74 | CDK6 | 0.52930975 |
| 75 | PRKCI | 0.52526189 |
| 76 | PRKCQ | 0.51131490 |
| 77 | CDK9 | 0.50365366 |
| 78 | ITK | 0.49834529 |
| 79 | CHUK | 0.49455664 |
| 80 | CDK7 | 0.48442835 |
| 81 | BCKDK | 0.48335838 |
| 82 | ILK | 0.47105205 |
| 83 | MAPKAPK5 | 0.46116361 |
| 84 | SYK | 0.45798311 |
| 85 | RPS6KA5 | 0.45492416 |
| 86 | MAP3K4 | 0.44479979 |
| 87 | PRKCH | 0.42952022 |
| 88 | PLK2 | 0.42932261 |
| 89 | SCYL2 | 0.41990361 |
| 90 | CSNK2A1 | 0.41445378 |
| 91 | ZAK | 0.40837344 |
| 92 | PRKCE | 0.34583399 |
| 93 | ATM | 0.33483195 |
| 94 | NME2 | 0.33468077 |
| 95 | STK39 | 0.33381653 |
| 96 | ADRBK1 | 0.32123472 |
| 97 | CSNK1E | 0.32008664 |
| 98 | MAP2K7 | 0.31452093 |
| 99 | NEK2 | 0.31086656 |
| 100 | MAPKAPK3 | 0.30180600 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.68692287 |
| 2 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.90370632 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.84438885 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.08512095 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.05608387 |
| 6 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.90754261 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.48994118 |
| 8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.48094276 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.41503827 |
| 10 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.33625547 |
| 11 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.32269710 |
| 12 | Basal transcription factors_Homo sapiens_hsa03022 | 2.31386584 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.26273090 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 2.08236338 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 2.03807990 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.98657867 |
| 17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.82276489 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.79600168 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.77811713 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.76446153 |
| 21 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.75122566 |
| 22 | Alzheimers disease_Homo sapiens_hsa05010 | 1.60618283 |
| 23 | Mismatch repair_Homo sapiens_hsa03430 | 1.55663511 |
| 24 | Homologous recombination_Homo sapiens_hsa03440 | 1.50056601 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.45215264 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.43710885 |
| 27 | RNA transport_Homo sapiens_hsa03013 | 1.37696604 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.36182641 |
| 29 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.23218940 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.21749993 |
| 31 | Ribosome_Homo sapiens_hsa03010 | 1.18837022 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.13091593 |
| 33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.04285774 |
| 34 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.04082314 |
| 35 | DNA replication_Homo sapiens_hsa03030 | 1.03993196 |
| 36 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.02913596 |
| 37 | Phototransduction_Homo sapiens_hsa04744 | 1.02562818 |
| 38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.02374068 |
| 39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.01749915 |
| 40 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.98791410 |
| 41 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.94331177 |
| 42 | Asthma_Homo sapiens_hsa05310 | 0.93907853 |
| 43 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.92508087 |
| 44 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.91804859 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 0.88861129 |
| 46 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.87545641 |
| 47 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.86247607 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.82518979 |
| 49 | Legionellosis_Homo sapiens_hsa05134 | 0.81945826 |
| 50 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.80226136 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.79801359 |
| 52 | Allograft rejection_Homo sapiens_hsa05330 | 0.79026532 |
| 53 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.77306805 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.74604846 |
| 55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.73171031 |
| 56 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.70713202 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.68774613 |
| 58 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.68147277 |
| 59 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.66702230 |
| 60 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.65932275 |
| 61 | Carbon metabolism_Homo sapiens_hsa01200 | 0.63999317 |
| 62 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.63222306 |
| 63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.63080262 |
| 64 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.60116263 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60017602 |
| 66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59643844 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.57986538 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57571073 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.56070132 |
| 70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51648789 |
| 71 | Base excision repair_Homo sapiens_hsa03410 | 0.51533770 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50288941 |
| 73 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.49433693 |
| 74 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.46603094 |
| 75 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.46136930 |
| 76 | Nicotine addiction_Homo sapiens_hsa05033 | 0.45983455 |
| 77 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.45729297 |
| 78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.41210795 |
| 79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40598055 |
| 80 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39711363 |
| 81 | Sulfur relay system_Homo sapiens_hsa04122 | 0.39237155 |
| 82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.37740784 |
| 83 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.35772559 |
| 84 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.33005910 |
| 85 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.32915817 |
| 86 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.32755553 |
| 87 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.32727888 |
| 88 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30089352 |
| 89 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.29438554 |
| 90 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.27743331 |
| 91 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.27033877 |
| 92 | Mineral absorption_Homo sapiens_hsa04978 | 0.26816122 |
| 93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.26243044 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.26010458 |
| 95 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.25462967 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.24916741 |
| 97 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.24577585 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.20289643 |
| 99 | Shigellosis_Homo sapiens_hsa05131 | 0.19530073 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.19327732 |

