

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cellular response to nicotine (GO:0071316) | 9.30423168 |
| 2 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 8.85727578 |
| 3 | eye photoreceptor cell differentiation (GO:0001754) | 8.28252747 |
| 4 | photoreceptor cell differentiation (GO:0046530) | 8.28252747 |
| 5 | positive regulation of meiosis (GO:0045836) | 6.55276400 |
| 6 | cartilage morphogenesis (GO:0060536) | 6.48455763 |
| 7 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 6.38073366 |
| 8 | positive regulation of meiotic cell cycle (GO:0051446) | 6.12402546 |
| 9 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 5.77997503 |
| 10 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 5.63690738 |
| 11 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 5.43051616 |
| 12 | mesenchymal cell proliferation (GO:0010463) | 5.29456172 |
| 13 | pituitary gland development (GO:0021983) | 4.94873113 |
| 14 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 4.61837573 |
| 15 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 4.36182997 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.24369593 |
| 17 | viral transcription (GO:0019083) | 4.22253142 |
| 18 | positive regulation of BMP signaling pathway (GO:0030513) | 4.18654345 |
| 19 | opioid receptor signaling pathway (GO:0038003) | 4.14690223 |
| 20 | translational termination (GO:0006415) | 4.12745605 |
| 21 | nonmotile primary cilium assembly (GO:0035058) | 4.07357133 |
| 22 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 4.05280639 |
| 23 | regulation of transcription regulatory region DNA binding (GO:2000677) | 4.00884962 |
| 24 | respiratory chain complex IV assembly (GO:0008535) | 3.99814474 |
| 25 | organelle disassembly (GO:1903008) | 3.96183092 |
| 26 | middle ear morphogenesis (GO:0042474) | 3.86601613 |
| 27 | protein complex biogenesis (GO:0070271) | 3.83707881 |
| 28 | axonemal dynein complex assembly (GO:0070286) | 3.82478304 |
| 29 | cardiac epithelial to mesenchymal transition (GO:0060317) | 3.80489774 |
| 30 | signal transduction involved in regulation of gene expression (GO:0023019) | 3.77903765 |
| 31 | sequestering of actin monomers (GO:0042989) | 3.73233323 |
| 32 | negative regulation of Ras GTPase activity (GO:0034261) | 3.72270312 |
| 33 | platelet dense granule organization (GO:0060155) | 3.68927700 |
| 34 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.66436624 |
| 35 | epithelial cilium movement (GO:0003351) | 3.64713043 |
| 36 | cytochrome complex assembly (GO:0017004) | 3.62951589 |
| 37 | positive regulation of growth hormone secretion (GO:0060124) | 3.58060996 |
| 38 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.57331799 |
| 39 | ribonucleoprotein complex disassembly (GO:0032988) | 3.55540754 |
| 40 | respiratory electron transport chain (GO:0022904) | 3.55177733 |
| 41 | ribosomal small subunit assembly (GO:0000028) | 3.55167643 |
| 42 | protein neddylation (GO:0045116) | 3.54621638 |
| 43 | maturation of SSU-rRNA (GO:0030490) | 3.50656336 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.50390608 |
| 45 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.50390608 |
| 46 | NADH dehydrogenase complex assembly (GO:0010257) | 3.50390608 |
| 47 | cotranslational protein targeting to membrane (GO:0006613) | 3.49914552 |
| 48 | electron transport chain (GO:0022900) | 3.48830984 |
| 49 | protein polyglutamylation (GO:0018095) | 3.47622051 |
| 50 | protein targeting to ER (GO:0045047) | 3.46331443 |
| 51 | DNA damage response, detection of DNA damage (GO:0042769) | 3.44382687 |
| 52 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.39320050 |
| 53 | behavioral response to nicotine (GO:0035095) | 3.39271105 |
| 54 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 3.37572830 |
| 55 | translational elongation (GO:0006414) | 3.36074677 |
| 56 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.34003418 |
| 57 | ATP synthesis coupled proton transport (GO:0015986) | 3.34003418 |
| 58 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.29641404 |
| 59 | postsynaptic membrane organization (GO:0001941) | 3.27151062 |
| 60 | ribosomal small subunit biogenesis (GO:0042274) | 3.24529110 |
| 61 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.23463351 |
| 62 | protein localization to endoplasmic reticulum (GO:0070972) | 3.18066754 |
| 63 | response to gravity (GO:0009629) | 3.15955503 |
| 64 | cellular protein complex disassembly (GO:0043624) | 3.13487675 |
| 65 | cilium movement (GO:0003341) | 3.10042768 |
| 66 | negative regulation of DNA binding (GO:0043392) | 3.08337651 |
| 67 | midbrain development (GO:0030901) | 3.07523241 |
| 68 | regulation of growth hormone secretion (GO:0060123) | 3.05616597 |
| 69 | viral life cycle (GO:0019058) | 3.03862100 |
| 70 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 3.02004046 |
| 71 | cellular response to vitamin D (GO:0071305) | 3.00018560 |
| 72 | embryonic hindlimb morphogenesis (GO:0035116) | 2.99253204 |
| 73 | spinal cord association neuron differentiation (GO:0021527) | 2.93730678 |
| 74 | replication fork processing (GO:0031297) | 2.89259273 |
| 75 | ribosomal large subunit biogenesis (GO:0042273) | 2.85367487 |
| 76 | regulation of cellular respiration (GO:0043457) | 2.85064413 |
| 77 | neuron fate determination (GO:0048664) | 2.82741874 |
| 78 | hindlimb morphogenesis (GO:0035137) | 2.81953272 |
| 79 | regulation of odontogenesis (GO:0042481) | 2.79234250 |
| 80 | retina layer formation (GO:0010842) | 2.78847963 |
| 81 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.77519049 |
| 82 | cilium morphogenesis (GO:0060271) | 2.76318798 |
| 83 | response to nicotine (GO:0035094) | 2.73021482 |
| 84 | brain morphogenesis (GO:0048854) | 2.72162299 |
| 85 | regulation of cilium movement (GO:0003352) | 2.71883514 |
| 86 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.71152445 |
| 87 | resolution of meiotic recombination intermediates (GO:0000712) | 2.70243911 |
| 88 | sperm motility (GO:0030317) | 2.69414542 |
| 89 | macromolecular complex disassembly (GO:0032984) | 2.69158958 |
| 90 | vasculature development (GO:0001944) | 2.67165120 |
| 91 | negative regulation of response to food (GO:0032096) | 2.66044104 |
| 92 | negative regulation of appetite (GO:0032099) | 2.66044104 |
| 93 | translational initiation (GO:0006413) | 2.62923742 |
| 94 | protein complex disassembly (GO:0043241) | 2.62564928 |
| 95 | sulfate transmembrane transport (GO:1902358) | 2.61174713 |
| 96 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.59338679 |
| 97 | striatum development (GO:0021756) | 2.57281181 |
| 98 | righting reflex (GO:0060013) | 2.53822747 |
| 99 | cell wall macromolecule catabolic process (GO:0016998) | 14.9212367 |
| 100 | cell wall macromolecule metabolic process (GO:0044036) | 12.4696615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.61867214 |
| 2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.10212777 |
| 3 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 4.09586761 |
| 4 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 4.03676326 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.63459577 |
| 6 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 3.18696748 |
| 7 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.92611838 |
| 8 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.66936131 |
| 9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.64120080 |
| 10 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.31613858 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.29778909 |
| 12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.25737693 |
| 13 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.23848813 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.22991574 |
| 15 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.21742623 |
| 16 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.09578395 |
| 17 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 2.03401995 |
| 18 | FUS_26573619_Chip-Seq_HEK293_Human | 2.00237419 |
| 19 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.98865557 |
| 20 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.96566850 |
| 21 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.84744265 |
| 22 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.82893447 |
| 23 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.82893447 |
| 24 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.74795042 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73420496 |
| 26 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.73355922 |
| 27 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.73355922 |
| 28 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.69992827 |
| 29 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.69904503 |
| 30 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.59801832 |
| 31 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.56688636 |
| 32 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.53984893 |
| 33 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.52463096 |
| 34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.51919873 |
| 35 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.51033457 |
| 36 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.50334573 |
| 37 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.49958790 |
| 38 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.49662981 |
| 39 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.46216335 |
| 40 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.45915682 |
| 41 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.44091893 |
| 42 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.41312898 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40022624 |
| 44 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37785065 |
| 45 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.36213802 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.35559670 |
| 47 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.30911681 |
| 48 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.29894130 |
| 49 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29757048 |
| 50 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.29268417 |
| 51 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.28886378 |
| 52 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.28290357 |
| 53 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.28121922 |
| 54 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.25498524 |
| 55 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.24106345 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.19973391 |
| 57 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.18543178 |
| 58 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.17611672 |
| 59 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17473536 |
| 60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.16846309 |
| 61 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.16510316 |
| 62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.15461930 |
| 63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.14576227 |
| 64 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.13777313 |
| 65 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12643637 |
| 66 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.12641042 |
| 67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.12561907 |
| 68 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.11826438 |
| 69 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.09584543 |
| 70 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.07811391 |
| 71 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.07089816 |
| 72 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.06813002 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06456858 |
| 74 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.03081096 |
| 75 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.00849630 |
| 76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.00418146 |
| 77 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.99886255 |
| 78 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.99857984 |
| 79 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.99128676 |
| 80 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97777846 |
| 81 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.97409457 |
| 82 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97297231 |
| 83 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.96452269 |
| 84 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.96220122 |
| 85 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94895726 |
| 86 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.94892466 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94197460 |
| 88 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94172216 |
| 89 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.91291636 |
| 90 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.91185943 |
| 91 | TCF4_23295773_ChIP-Seq_U87_Human | 0.91090094 |
| 92 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.91019414 |
| 93 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.90258129 |
| 94 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.89497611 |
| 95 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.89437588 |
| 96 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.89347155 |
| 97 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.88898594 |
| 98 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.87624802 |
| 99 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.86309994 |
| 100 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.85627363 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 5.80092960 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.00390038 |
| 3 | MP0001968_abnormal_touch/_nociception | 3.53213659 |
| 4 | MP0002736_abnormal_nociception_after | 2.60131426 |
| 5 | MP0001188_hyperpigmentation | 2.55490531 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.50874310 |
| 7 | MP0000049_abnormal_middle_ear | 2.37044298 |
| 8 | MP0004142_abnormal_muscle_tone | 2.33610948 |
| 9 | MP0005551_abnormal_eye_electrophysiolog | 2.23578331 |
| 10 | MP0002735_abnormal_chemical_nociception | 2.20732504 |
| 11 | MP0001293_anophthalmia | 2.19710928 |
| 12 | MP0004145_abnormal_muscle_electrophysio | 2.13476736 |
| 13 | MP0002734_abnormal_mechanical_nocicepti | 2.08723404 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.02027819 |
| 15 | MP0000631_abnormal_neuroendocrine_gland | 1.98513121 |
| 16 | MP0000778_abnormal_nervous_system | 1.94588464 |
| 17 | MP0002163_abnormal_gland_morphology | 1.88887065 |
| 18 | MP0005174_abnormal_tail_pigmentation | 1.78001595 |
| 19 | MP0003879_abnormal_hair_cell | 1.76532350 |
| 20 | MP0003122_maternal_imprinting | 1.74070513 |
| 21 | MP0001486_abnormal_startle_reflex | 1.73445808 |
| 22 | MP0006276_abnormal_autonomic_nervous | 1.70274669 |
| 23 | MP0002234_abnormal_pharynx_morphology | 1.69060309 |
| 24 | MP0008877_abnormal_DNA_methylation | 1.67919771 |
| 25 | MP0003890_abnormal_embryonic-extraembry | 1.62991290 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.60605711 |
| 27 | MP0002928_abnormal_bile_duct | 1.59877397 |
| 28 | MP0000569_abnormal_digit_pigmentation | 1.58951103 |
| 29 | MP0005670_abnormal_white_adipose | 1.58715688 |
| 30 | MP0004742_abnormal_vestibular_system | 1.58589173 |
| 31 | MP0003787_abnormal_imprinting | 1.57934951 |
| 32 | MP0003937_abnormal_limbs/digits/tail_de | 1.52736765 |
| 33 | MP0004381_abnormal_hair_follicle | 1.52037749 |
| 34 | MP0002272_abnormal_nervous_system | 1.50743740 |
| 35 | MP0005499_abnormal_olfactory_system | 1.50083739 |
| 36 | MP0005394_taste/olfaction_phenotype | 1.50083739 |
| 37 | MP0002837_dystrophic_cardiac_calcinosis | 1.49623883 |
| 38 | MP0005423_abnormal_somatic_nervous | 1.46252991 |
| 39 | MP0002177_abnormal_outer_ear | 1.45511474 |
| 40 | MP0002938_white_spotting | 1.44233159 |
| 41 | MP0001984_abnormal_olfaction | 1.43991424 |
| 42 | MP0002184_abnormal_innervation | 1.40681005 |
| 43 | MP0004019_abnormal_vitamin_homeostasis | 1.38095700 |
| 44 | MP0009250_abnormal_appendicular_skeleto | 1.38022946 |
| 45 | MP0001440_abnormal_grooming_behavior | 1.36938407 |
| 46 | MP0002697_abnormal_eye_size | 1.35234700 |
| 47 | MP0003880_abnormal_central_pattern | 1.33236708 |
| 48 | MP0005379_endocrine/exocrine_gland_phen | 1.32059352 |
| 49 | MP0001970_abnormal_pain_threshold | 1.30648570 |
| 50 | MP0001286_abnormal_eye_development | 1.29972327 |
| 51 | MP0005195_abnormal_posterior_eye | 1.25688074 |
| 52 | MP0003755_abnormal_palate_morphology | 1.24357392 |
| 53 | MP0000955_abnormal_spinal_cord | 1.21988497 |
| 54 | MP0001986_abnormal_taste_sensitivity | 1.18400017 |
| 55 | MP0001542_abnormal_bone_strength | 1.18209971 |
| 56 | MP0008995_early_reproductive_senescence | 1.17894881 |
| 57 | MP0004885_abnormal_endolymph | 1.17684398 |
| 58 | MP0004043_abnormal_pH_regulation | 1.16075897 |
| 59 | MP0002638_abnormal_pupillary_reflex | 1.14438323 |
| 60 | MP0006072_abnormal_retinal_apoptosis | 1.13563685 |
| 61 | MP0002067_abnormal_sensory_capabilities | 1.12736153 |
| 62 | MP0002733_abnormal_thermal_nociception | 1.11732494 |
| 63 | MP0009745_abnormal_behavioral_response | 1.11723070 |
| 64 | MP0001963_abnormal_hearing_physiology | 1.11547338 |
| 65 | MP0002752_abnormal_somatic_nervous | 1.09638713 |
| 66 | MP0003385_abnormal_body_wall | 1.07706984 |
| 67 | MP0005171_absent_coat_pigmentation | 1.07524879 |
| 68 | MP0008789_abnormal_olfactory_epithelium | 1.06989626 |
| 69 | MP0005410_abnormal_fertilization | 1.00221574 |
| 70 | MP0001905_abnormal_dopamine_level | 0.98259462 |
| 71 | MP0001485_abnormal_pinna_reflex | 0.98227344 |
| 72 | MP0004270_analgesia | 0.96151802 |
| 73 | MP0003646_muscle_fatigue | 0.95407206 |
| 74 | MP0000427_abnormal_hair_cycle | 0.94473269 |
| 75 | MP0009046_muscle_twitch | 0.94327009 |
| 76 | MP0002572_abnormal_emotion/affect_behav | 0.92969397 |
| 77 | MP0001324_abnormal_eye_pigmentation | 0.90833109 |
| 78 | MP0005187_abnormal_penis_morphology | 0.90737504 |
| 79 | MP0003121_genomic_imprinting | 0.90203289 |
| 80 | MP0002063_abnormal_learning/memory/cond | 0.90041956 |
| 81 | MP0003698_abnormal_male_reproductive | 0.89033793 |
| 82 | MP0003635_abnormal_synaptic_transmissio | 0.88988177 |
| 83 | MP0002109_abnormal_limb_morphology | 0.88543063 |
| 84 | MP0005084_abnormal_gallbladder_morpholo | 0.88167102 |
| 85 | MP0009697_abnormal_copulation | 0.86831141 |
| 86 | MP0003186_abnormal_redox_activity | 0.86305873 |
| 87 | MP0000026_abnormal_inner_ear | 0.84856578 |
| 88 | MP0005391_vision/eye_phenotype | 0.84347967 |
| 89 | MP0002751_abnormal_autonomic_nervous | 0.83844738 |
| 90 | MP0002557_abnormal_social/conspecific_i | 0.82996481 |
| 91 | MP0001919_abnormal_reproductive_system | 0.82759714 |
| 92 | MP0002064_seizures | 0.82588015 |
| 93 | MP0008875_abnormal_xenobiotic_pharmacok | 0.81541802 |
| 94 | MP0002882_abnormal_neuron_morphology | 0.80639626 |
| 95 | MP0002653_abnormal_ependyma_morphology | 0.80282169 |
| 96 | MP0005253_abnormal_eye_physiology | 0.79687746 |
| 97 | MP0002092_abnormal_eye_morphology | 0.79089434 |
| 98 | MP0000428_abnormal_craniofacial_morphol | 0.76840603 |
| 99 | MP0003861_abnormal_nervous_system | 0.75553799 |
| 100 | MP0001529_abnormal_vocalization | 0.74612215 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pigmentary retinal degeneration (HP:0001146) | 7.00951144 |
| 2 | Ridged nail (HP:0001807) | 4.90386440 |
| 3 | Reticulocytopenia (HP:0001896) | 4.41357605 |
| 4 | Abnormal ciliary motility (HP:0012262) | 4.00774027 |
| 5 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.92908168 |
| 6 | Absent/shortened dynein arms (HP:0200106) | 3.92908168 |
| 7 | Absent eyebrow (HP:0002223) | 3.64231231 |
| 8 | Supernumerary spleens (HP:0009799) | 3.39822615 |
| 9 | Premature skin wrinkling (HP:0100678) | 3.39237442 |
| 10 | Septo-optic dysplasia (HP:0100842) | 3.36317441 |
| 11 | Anhidrosis (HP:0000970) | 3.25569664 |
| 12 | Nephronophthisis (HP:0000090) | 3.19711002 |
| 13 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.18613290 |
| 14 | Medial flaring of the eyebrow (HP:0010747) | 3.14700993 |
| 15 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.95435332 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 2.95068036 |
| 17 | Abnormality of midbrain morphology (HP:0002418) | 2.95068036 |
| 18 | Hemiparesis (HP:0001269) | 2.92198021 |
| 19 | Acute necrotizing encephalopathy (HP:0006965) | 2.87288960 |
| 20 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.85841332 |
| 21 | Stenosis of the external auditory canal (HP:0000402) | 2.80909348 |
| 22 | Chronic hepatic failure (HP:0100626) | 2.70451648 |
| 23 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.67472258 |
| 24 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.67472258 |
| 25 | Gait imbalance (HP:0002141) | 2.66340418 |
| 26 | Vaginal atresia (HP:0000148) | 2.63798391 |
| 27 | Type II lissencephaly (HP:0007260) | 2.62791051 |
| 28 | Genital tract atresia (HP:0001827) | 2.56206219 |
| 29 | Congenital primary aphakia (HP:0007707) | 2.51295596 |
| 30 | Abnormality of the renal medulla (HP:0100957) | 2.49029108 |
| 31 | Progressive macrocephaly (HP:0004481) | 2.41105120 |
| 32 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.40000553 |
| 33 | Hypodontia (HP:0000668) | 2.37551764 |
| 34 | Macrocytic anemia (HP:0001972) | 2.35409579 |
| 35 | Abnormality of vitamin B metabolism (HP:0004340) | 2.34636962 |
| 36 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.33201116 |
| 37 | Mitochondrial inheritance (HP:0001427) | 2.30936342 |
| 38 | Hyperglycinemia (HP:0002154) | 2.29925811 |
| 39 | Acute encephalopathy (HP:0006846) | 2.28324260 |
| 40 | Abnormality of primary teeth (HP:0006481) | 2.27561903 |
| 41 | Cerebellar dysplasia (HP:0007033) | 2.25701239 |
| 42 | Cerebral edema (HP:0002181) | 2.25446493 |
| 43 | Fine hair (HP:0002213) | 2.22826996 |
| 44 | Nephrogenic diabetes insipidus (HP:0009806) | 2.22303866 |
| 45 | Asplenia (HP:0001746) | 2.20816909 |
| 46 | Absent hair (HP:0002298) | 2.17700681 |
| 47 | Increased CSF lactate (HP:0002490) | 2.16950446 |
| 48 | Respiratory difficulties (HP:0002880) | 2.16125540 |
| 49 | Disproportionate short-trunk short stature (HP:0003521) | 2.09313092 |
| 50 | Hyperventilation (HP:0002883) | 2.08325003 |
| 51 | Pancreatic fibrosis (HP:0100732) | 2.08264389 |
| 52 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.07467709 |
| 53 | Congenital stationary night blindness (HP:0007642) | 2.06993654 |
| 54 | Optic disc pallor (HP:0000543) | 2.06222838 |
| 55 | Myokymia (HP:0002411) | 2.05253383 |
| 56 | Amelogenesis imperfecta (HP:0000705) | 2.04650154 |
| 57 | Increased hepatocellular lipid droplets (HP:0006565) | 2.03023116 |
| 58 | Concave nail (HP:0001598) | 11.2977751 |
| 59 | Absent septum pellucidum (HP:0001331) | 1.98818707 |
| 60 | Depressed nasal ridge (HP:0000457) | 1.95820151 |
| 61 | Type 2 muscle fiber atrophy (HP:0003554) | 1.95533095 |
| 62 | Hypotrichosis (HP:0001006) | 1.93049962 |
| 63 | Polycystic ovaries (HP:0000147) | 1.88369218 |
| 64 | Abnormal hemoglobin (HP:0011902) | 1.84987301 |
| 65 | True hermaphroditism (HP:0010459) | 1.81536792 |
| 66 | Abnormality of the pons (HP:0007361) | 1.79627655 |
| 67 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.79608697 |
| 68 | Hypoplasia of the pons (HP:0012110) | 1.78874394 |
| 69 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.75799444 |
| 70 | Postural instability (HP:0002172) | 1.75047046 |
| 71 | Renal Fanconi syndrome (HP:0001994) | 1.74753402 |
| 72 | Hypoplasia of the radius (HP:0002984) | 1.74472589 |
| 73 | Abnormal hair whorl (HP:0010721) | 1.74064742 |
| 74 | Glycosuria (HP:0003076) | 1.73594364 |
| 75 | Abnormality of urine glucose concentration (HP:0011016) | 1.73594364 |
| 76 | Pallor (HP:0000980) | 1.72555315 |
| 77 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.72457224 |
| 78 | Abnormality of glycine metabolism (HP:0010895) | 1.72457224 |
| 79 | Malignant hyperthermia (HP:0002047) | 1.72419402 |
| 80 | Sparse eyelashes (HP:0000653) | 1.71989146 |
| 81 | Global brain atrophy (HP:0002283) | 1.71884791 |
| 82 | Absent eyelashes (HP:0000561) | 1.70843539 |
| 83 | 3-Methylglutaconic aciduria (HP:0003535) | 1.70703371 |
| 84 | Poor coordination (HP:0002370) | 1.70620990 |
| 85 | Hypoplastic toenails (HP:0001800) | 1.67317023 |
| 86 | Methylmalonic acidemia (HP:0002912) | 1.67055997 |
| 87 | Progressive cerebellar ataxia (HP:0002073) | 1.65269585 |
| 88 | Lipid accumulation in hepatocytes (HP:0006561) | 1.64958715 |
| 89 | Short 4th metacarpal (HP:0010044) | 1.63618879 |
| 90 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.63618879 |
| 91 | Pancreatic cysts (HP:0001737) | 1.63524188 |
| 92 | Oligodontia (HP:0000677) | 1.62288767 |
| 93 | Occipital encephalocele (HP:0002085) | 1.61090376 |
| 94 | Abnormality of the vitreous humor (HP:0004327) | 1.60560523 |
| 95 | Abnormal number of erythroid precursors (HP:0012131) | 1.60205720 |
| 96 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.60016335 |
| 97 | Bilateral microphthalmos (HP:0007633) | 1.59672746 |
| 98 | Midline defect of the nose (HP:0004122) | 1.59670843 |
| 99 | Abnormality of vitamin metabolism (HP:0100508) | 1.59375220 |
| 100 | Morphological abnormality of the middle ear (HP:0008609) | 1.58683110 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 8.58516051 |
| 2 | BCKDK | 3.94880283 |
| 3 | AKT3 | 3.54605385 |
| 4 | PNCK | 3.11322229 |
| 5 | STK16 | 2.57506787 |
| 6 | EPHA3 | 2.36774702 |
| 7 | MAP3K11 | 2.27688304 |
| 8 | PINK1 | 2.22845212 |
| 9 | MAP3K12 | 2.13149181 |
| 10 | MAPK15 | 1.94611205 |
| 11 | SIK2 | 1.85113013 |
| 12 | SGK2 | 1.73356195 |
| 13 | TNIK | 1.71633816 |
| 14 | TLK1 | 1.70643290 |
| 15 | DYRK3 | 1.70246051 |
| 16 | CDK19 | 1.68671934 |
| 17 | MAP4K1 | 1.67618047 |
| 18 | DYRK2 | 1.66377304 |
| 19 | SGK223 | 1.55751168 |
| 20 | SGK494 | 1.55751168 |
| 21 | TYRO3 | 1.34337944 |
| 22 | ADRBK2 | 1.30853594 |
| 23 | MAP3K4 | 1.30601642 |
| 24 | TXK | 1.29332091 |
| 25 | MAP2K4 | 1.27654229 |
| 26 | OXSR1 | 1.24538236 |
| 27 | MAPK13 | 1.21822193 |
| 28 | MAP2K7 | 1.16468571 |
| 29 | PAK3 | 1.11798347 |
| 30 | MAP4K2 | 1.10970285 |
| 31 | NTRK2 | 1.06533881 |
| 32 | CSNK1A1L | 1.02976362 |
| 33 | CDK3 | 0.94918902 |
| 34 | PHKG2 | 0.93948084 |
| 35 | PHKG1 | 0.93948084 |
| 36 | GRK1 | 0.93871146 |
| 37 | SGK3 | 0.91720169 |
| 38 | MARK3 | 0.89039246 |
| 39 | BRAF | 0.88753525 |
| 40 | NEK1 | 0.85952235 |
| 41 | WNK4 | 0.83747598 |
| 42 | CSNK1G3 | 0.81431674 |
| 43 | VRK1 | 0.81038040 |
| 44 | CDC7 | 0.79808889 |
| 45 | WNK3 | 0.78713358 |
| 46 | CSNK1G1 | 0.76653087 |
| 47 | CSNK1G2 | 0.75915818 |
| 48 | PRKCG | 0.72371060 |
| 49 | CAMK1 | 0.72136083 |
| 50 | MUSK | 0.70098939 |
| 51 | MARK1 | 0.69449448 |
| 52 | INSRR | 0.68878837 |
| 53 | TNK2 | 0.67484173 |
| 54 | MINK1 | 0.65197309 |
| 55 | DYRK1A | 0.65128764 |
| 56 | TSSK6 | 0.58138939 |
| 57 | PRKCE | 0.57949060 |
| 58 | MKNK1 | 0.53464461 |
| 59 | CAMKK2 | 0.49933139 |
| 60 | NUAK1 | 0.49922933 |
| 61 | CAMKK1 | 0.49808862 |
| 62 | CAMK2A | 0.48834549 |
| 63 | ZAK | 0.48817234 |
| 64 | CDK15 | 0.48712654 |
| 65 | MAP3K5 | 0.47304460 |
| 66 | TRIM28 | 0.47206111 |
| 67 | PASK | 0.47053264 |
| 68 | NTRK1 | 0.46865085 |
| 69 | EIF2AK1 | 0.46727182 |
| 70 | WNK1 | 0.46454735 |
| 71 | CAMK1G | 0.45317007 |
| 72 | CDK18 | 0.45290822 |
| 73 | PRKACA | 0.45266262 |
| 74 | DYRK1B | 0.44489685 |
| 75 | CASK | 0.43172389 |
| 76 | CDK14 | 0.43139699 |
| 77 | PRKCZ | 0.42976510 |
| 78 | CAMK4 | 0.41161871 |
| 79 | CDK5 | 0.40510051 |
| 80 | CSNK1E | 0.40351501 |
| 81 | CDK11A | 0.40155292 |
| 82 | CSNK2A2 | 0.39928417 |
| 83 | SGK1 | 0.39551564 |
| 84 | PLK4 | 0.39302864 |
| 85 | MKNK2 | 0.38014366 |
| 86 | OBSCN | 0.35432169 |
| 87 | RPS6KA1 | 0.35230527 |
| 88 | PRKG1 | 0.34689508 |
| 89 | PRKCB | 0.33479930 |
| 90 | CSNK2A1 | 0.31554085 |
| 91 | PRKCI | 0.31071330 |
| 92 | AURKB | 0.30608084 |
| 93 | CSNK1A1 | 0.28093662 |
| 94 | MAPK14 | 0.26904804 |
| 95 | PKN1 | 0.26588968 |
| 96 | PRKACB | 0.25798827 |
| 97 | GRK7 | 0.25723395 |
| 98 | PDK2 | 0.25624063 |
| 99 | PRKACG | 0.25454470 |
| 100 | PLK3 | 0.24353675 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.72381899 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.46696064 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.13606862 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.67764343 |
| 5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.25039593 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 3.02189855 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 3.01408727 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.99405708 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.84903925 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.66801971 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.21699423 |
| 12 | Nicotine addiction_Homo sapiens_hsa05033 | 2.06249985 |
| 13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.06102314 |
| 14 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.89636496 |
| 15 | Morphine addiction_Homo sapiens_hsa05032 | 1.78502026 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.57498775 |
| 17 | GABAergic synapse_Homo sapiens_hsa04727 | 1.51350261 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.39598316 |
| 19 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.35506584 |
| 20 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.33201672 |
| 21 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.26445442 |
| 22 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.24492082 |
| 23 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.23055686 |
| 24 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.22958874 |
| 25 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.20936978 |
| 26 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.20607845 |
| 27 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.17535667 |
| 28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.17233959 |
| 29 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.16914740 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.16319584 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.15957189 |
| 32 | Circadian entrainment_Homo sapiens_hsa04713 | 1.14655666 |
| 33 | Insulin secretion_Homo sapiens_hsa04911 | 1.10942364 |
| 34 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.10265348 |
| 35 | Olfactory transduction_Homo sapiens_hsa04740 | 0.98938950 |
| 36 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.98336888 |
| 37 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.97336039 |
| 38 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.95830263 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.94567706 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 0.92221270 |
| 41 | Melanogenesis_Homo sapiens_hsa04916 | 0.91738000 |
| 42 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.88943675 |
| 43 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.87924585 |
| 44 | RNA degradation_Homo sapiens_hsa03018 | 0.87173362 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.86935145 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.84749175 |
| 47 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.84613760 |
| 48 | Cocaine addiction_Homo sapiens_hsa05030 | 0.84480661 |
| 49 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.83878494 |
| 50 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.82385543 |
| 51 | Proteasome_Homo sapiens_hsa03050 | 0.80287602 |
| 52 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.79527615 |
| 53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.76471189 |
| 54 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.74867037 |
| 55 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.72351587 |
| 56 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.71226032 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64576106 |
| 58 | Axon guidance_Homo sapiens_hsa04360 | 0.63528835 |
| 59 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.62259813 |
| 60 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.60139409 |
| 61 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.58295416 |
| 62 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55405456 |
| 63 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.55253130 |
| 64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53601151 |
| 65 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.50601252 |
| 66 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.48528509 |
| 67 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.47918559 |
| 68 | Taste transduction_Homo sapiens_hsa04742 | 0.47193677 |
| 69 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.44134685 |
| 70 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.43778986 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.43217808 |
| 72 | Mineral absorption_Homo sapiens_hsa04978 | 0.42313686 |
| 73 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42210145 |
| 74 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41321519 |
| 75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.40544171 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.40061785 |
| 77 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.39231482 |
| 78 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.38317803 |
| 79 | Homologous recombination_Homo sapiens_hsa03440 | 0.37743815 |
| 80 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.37602384 |
| 81 | RNA transport_Homo sapiens_hsa03013 | 0.37521201 |
| 82 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.37094403 |
| 83 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.35700826 |
| 84 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.34911675 |
| 85 | Long-term depression_Homo sapiens_hsa04730 | 0.34448835 |
| 86 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.33823420 |
| 87 | Alcoholism_Homo sapiens_hsa05034 | 0.33069568 |
| 88 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32485717 |
| 89 | Bile secretion_Homo sapiens_hsa04976 | 0.32442184 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.31514321 |
| 91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.31074257 |
| 92 | Salivary secretion_Homo sapiens_hsa04970 | 0.27597116 |
| 93 | Peroxisome_Homo sapiens_hsa04146 | 0.25636679 |
| 94 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.25117805 |
| 95 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.24147626 |
| 96 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.23004760 |
| 97 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22855738 |
| 98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.22358146 |
| 99 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.21751772 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.21316366 |

