TPT1P13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.91437832
2positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)7.19117156
3regulation of isotype switching to IgG isotypes (GO:0048302)6.96945553
4regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)6.37910121
5regulation of immunoglobulin secretion (GO:0051023)6.28914126
6viral transcription (GO:0019083)5.93646785
7translational termination (GO:0006415)5.65722703
8ribosomal large subunit biogenesis (GO:0042273)5.50829321
9ribosomal small subunit biogenesis (GO:0042274)5.21844018
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.10163971
11positive regulation of DNA recombination (GO:0045911)5.07971358
12positive regulation of isotype switching (GO:0045830)5.05620688
13CENP-A containing nucleosome assembly (GO:0034080)5.05488781
14translational elongation (GO:0006414)5.03732152
15kinetochore assembly (GO:0051382)4.99724966
16cotranslational protein targeting to membrane (GO:0006613)4.99470882
17protein targeting to ER (GO:0045047)4.88114656
18chromatin remodeling at centromere (GO:0031055)4.83029323
19regulation of podosome assembly (GO:0071801)4.77565844
20establishment of protein localization to endoplasmic reticulum (GO:0072599)4.73268330
21protein localization to endoplasmic reticulum (GO:0070972)4.66198260
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.62683317
23translational initiation (GO:0006413)4.61930294
24kinetochore organization (GO:0051383)4.56485555
25proteasome assembly (GO:0043248)4.37897778
26viral life cycle (GO:0019058)4.29364110
27cellular protein complex disassembly (GO:0043624)4.22146475
28negative regulation of acute inflammatory response (GO:0002674)4.13083875
29response to pheromone (GO:0019236)4.00698536
30DNA replication checkpoint (GO:0000076)3.92708790
31ribonucleoprotein complex biogenesis (GO:0022613)3.89382207
32maturation of SSU-rRNA (GO:0030490)3.85538235
33regulation of regulatory T cell differentiation (GO:0045589)3.84567368
34histone exchange (GO:0043486)3.80418304
35translation (GO:0006412)3.79826148
36CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.79039400
37negative regulation of JAK-STAT cascade (GO:0046426)3.78296993
38mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.77474546
39DNA methylation involved in gamete generation (GO:0043046)3.76855400
40purine deoxyribonucleotide catabolic process (GO:0009155)3.75388742
41piRNA metabolic process (GO:0034587)3.74150987
42DNA replication-independent nucleosome organization (GO:0034724)3.67283573
43DNA replication-independent nucleosome assembly (GO:0006336)3.67283573
44ncRNA 3-end processing (GO:0043628)3.67270845
45somatic hypermutation of immunoglobulin genes (GO:0016446)3.66799426
46somatic diversification of immune receptors via somatic mutation (GO:0002566)3.66799426
47protein complex biogenesis (GO:0070271)3.61919788
48mitotic nuclear envelope reassembly (GO:0007084)3.61590884
49nuclear envelope reassembly (GO:0031468)3.61590884
50mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.60016073
51mitochondrial respiratory chain complex I assembly (GO:0032981)3.60016073
52NADH dehydrogenase complex assembly (GO:0010257)3.60016073
53positive regulation of immunoglobulin production (GO:0002639)3.59928250
54positive regulation of interleukin-17 production (GO:0032740)3.56800254
55regulation of helicase activity (GO:0051095)3.54225168
56negative regulation of B cell apoptotic process (GO:0002903)3.52583859
57cellular component biogenesis (GO:0044085)3.49413988
58energy coupled proton transport, down electrochemical gradient (GO:0015985)3.48161546
59ATP synthesis coupled proton transport (GO:0015986)3.48161546
60protein complex disassembly (GO:0043241)3.46213716
61maturation of 5.8S rRNA (GO:0000460)3.43404795
62L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.41302134
63negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.40838468
64negative regulation of T-helper cell differentiation (GO:0045623)3.40838468
65regulation of MHC class II biosynthetic process (GO:0045346)3.37954963
66macromolecular complex disassembly (GO:0032984)3.37258107
67nuclear-transcribed mRNA catabolic process (GO:0000956)3.36826737
68formation of translation preinitiation complex (GO:0001731)3.34316126
69chaperone-mediated protein transport (GO:0072321)3.33981214
70positive regulation of granulocyte differentiation (GO:0030854)3.32862703
71rRNA processing (GO:0006364)3.31170030
72mitochondrial respiratory chain complex assembly (GO:0033108)3.29016321
73regulation of chronic inflammatory response (GO:0002676)3.28217348
74positive regulation of activated T cell proliferation (GO:0042104)3.26091823
75DNA ligation (GO:0006266)3.24482922
76protein targeting to membrane (GO:0006612)3.24363351
77rRNA metabolic process (GO:0016072)3.23897264
78deoxyribose phosphate catabolic process (GO:0046386)3.19163322
79synapsis (GO:0007129)3.18977206
80regulation of isotype switching (GO:0045191)3.17438728
81regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.16652944
82regulation of mitotic spindle checkpoint (GO:1903504)3.16652944
83mRNA catabolic process (GO:0006402)3.13926381
84purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.12447801
85exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.11160756
86negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.10827097
87cytokine production involved in immune response (GO:0002367)3.08137008
88positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.02685401
89mismatch repair (GO:0006298)3.00524384
90organelle disassembly (GO:1903008)2.99860746
91negative regulation of fibroblast apoptotic process (GO:2000270)2.96886225
92deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.96077501
93nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.96049527
94regulation of proton transport (GO:0010155)2.95825897
95purine deoxyribonucleotide metabolic process (GO:0009151)2.92304925
96base-excision repair, AP site formation (GO:0006285)2.91708929
97regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.89817314
98RNA catabolic process (GO:0006401)2.89107103
99ribosome biogenesis (GO:0042254)2.87926344
100protein targeting to mitochondrion (GO:0006626)2.86365141

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.76305703
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.71104730
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.60473259
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.71619858
5MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.61540139
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.52637288
7CREB1_15753290_ChIP-ChIP_HEK293T_Human3.42281427
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.26946340
9E2F7_22180533_ChIP-Seq_HELA_Human3.21638785
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.15343923
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.00505539
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.97451654
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.82117382
14VDR_23849224_ChIP-Seq_CD4+_Human2.79029447
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.55098400
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.54910876
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.53307265
18FOXP3_21729870_ChIP-Seq_TREG_Human2.49291997
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.42919094
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.38748009
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33590537
22MYC_19030024_ChIP-ChIP_MESCs_Mouse2.30631425
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.26800076
24ELK1_19687146_ChIP-ChIP_HELA_Human2.24207736
25FOXM1_23109430_ChIP-Seq_U2OS_Human2.22263489
26VDR_22108803_ChIP-Seq_LS180_Human2.16814738
27DCP1A_22483619_ChIP-Seq_HELA_Human2.11113168
28IRF1_19129219_ChIP-ChIP_H3396_Human2.08425746
29PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.08345868
30TTF2_22483619_ChIP-Seq_HELA_Human2.05394309
31NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.01051957
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.98887089
33XRN2_22483619_ChIP-Seq_HELA_Human1.95989103
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.93968035
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.92915998
36EWS_26573619_Chip-Seq_HEK293_Human1.92608919
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.77827499
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74798728
39PADI4_21655091_ChIP-ChIP_MCF-7_Human1.67352482
40PCGF2_27294783_Chip-Seq_ESCs_Mouse1.66376359
41GATA1_22025678_ChIP-Seq_K562_Human1.62802782
42ZNF274_21170338_ChIP-Seq_K562_Hela1.61270755
43TAF15_26573619_Chip-Seq_HEK293_Human1.59882189
44GABP_19822575_ChIP-Seq_HepG2_Human1.59853891
45HOXB4_20404135_ChIP-ChIP_EML_Mouse1.58673448
46MYC_18940864_ChIP-ChIP_HL60_Human1.52021651
47POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.51520949
48FUS_26573619_Chip-Seq_HEK293_Human1.48194619
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46064233
50ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.45401221
51E2F1_21310950_ChIP-Seq_MCF-7_Human1.44995901
52SRF_21415370_ChIP-Seq_HL-1_Mouse1.42972830
53HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.26429000
54HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.23437937
55YY1_21170310_ChIP-Seq_MESCs_Mouse1.22692415
56AR_21909140_ChIP-Seq_LNCAP_Human1.19831876
57GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19105506
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18896436
59KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.18561356
60MYCN_18555785_ChIP-Seq_MESCs_Mouse1.16622326
61FOXA1_25329375_ChIP-Seq_VCAP_Human1.13933017
62FOXA1_27270436_Chip-Seq_PROSTATE_Human1.13933017
63TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.13160694
64ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11476211
65CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.11335199
66TP53_22573176_ChIP-Seq_HFKS_Human1.10475255
67NELFA_20434984_ChIP-Seq_ESCs_Mouse1.09386438
68YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08806231
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.07644759
70POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07382345
71SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.04854707
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.02934151
73BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98615678
74CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97752877
75PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96056076
76ELK1_22589737_ChIP-Seq_MCF10A_Human0.95803209
77IGF1R_20145208_ChIP-Seq_DFB_Human0.95432439
78LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92611018
79FOXH1_21741376_ChIP-Seq_EPCs_Human0.92051097
80FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.91905102
81PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90980076
82ERG_20887958_ChIP-Seq_HPC-7_Mouse0.87607107
83NOTCH1_21737748_ChIP-Seq_TLL_Human0.85779241
84SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.84105356
85NFE2_27457419_Chip-Seq_LIVER_Mouse0.83899504
86CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.82713179
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.81841175
88CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.81783789
89ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.81504337
90SPI1_23547873_ChIP-Seq_NB4_Human0.80682286
91AR_20517297_ChIP-Seq_VCAP_Human0.79805410
92SUZ12_27294783_Chip-Seq_NPCs_Mouse0.79442529
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.78996037
94MYB_26560356_Chip-Seq_TH2_Human0.77832116
95FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77450198
96GATA3_26560356_Chip-Seq_TH2_Human0.76851877
97SALL4_22934838_ChIP-ChIP_CD34+_Human0.76502475
98AUTS2_25519132_ChIP-Seq_293T-REX_Human0.76002257
99RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.74951508
100CBP_20019798_ChIP-Seq_JUKART_Human0.71277635

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004147_increased_porphyrin_level6.06594690
2MP0001348_abnormal_lacrimal_gland4.98247369
3MP0003283_abnormal_digestive_organ4.25818199
4MP0008058_abnormal_DNA_repair3.31203418
5MP0001835_abnormal_antigen_presentation3.22310649
6MP0010094_abnormal_chromosome_stability3.15320293
7MP0008877_abnormal_DNA_methylation2.98781492
8MP0004957_abnormal_blastocyst_morpholog2.86080646
9MP0003806_abnormal_nucleotide_metabolis2.84250402
10MP0005075_abnormal_melanosome_morpholog2.81393935
11MP0001853_heart_inflammation2.77755182
12MP0001873_stomach_inflammation2.59441520
13MP0001529_abnormal_vocalization2.40734317
14MP0006292_abnormal_olfactory_placode2.32646981
15MP0006054_spinal_hemorrhage2.20691243
16MP0003567_abnormal_fetal_cardiomyocyte2.18463926
17MP0005310_abnormal_salivary_gland2.11976289
18MP0004145_abnormal_muscle_electrophysio2.07589003
19MP0003186_abnormal_redox_activity2.01494010
20MP0008872_abnormal_physiological_respon2.00255227
21MP0001727_abnormal_embryo_implantation1.94436017
22MP0005085_abnormal_gallbladder_physiolo1.89400842
23MP0004885_abnormal_endolymph1.86071145
24MP0009379_abnormal_foot_pigmentation1.85186530
25MP0005671_abnormal_response_to1.81135975
26MP0008057_abnormal_DNA_replication1.78031577
27MP0001440_abnormal_grooming_behavior1.73069431
28MP0008875_abnormal_xenobiotic_pharmacok1.72200221
29MP0003786_premature_aging1.62065887
30MP0003252_abnormal_bile_duct1.60511498
31MP0006082_CNS_inflammation1.55776202
32MP0003111_abnormal_nucleus_morphology1.54137845
33MP0005646_abnormal_pituitary_gland1.51153629
34MP0002160_abnormal_reproductive_system1.50097015
35MP0005220_abnormal_exocrine_pancreas1.49765329
36MP0003077_abnormal_cell_cycle1.49758815
37MP0002837_dystrophic_cardiac_calcinosis1.44237363
38MP0006036_abnormal_mitochondrial_physio1.43763451
39MP0003300_gastrointestinal_ulcer1.41868839
40MP0000678_abnormal_parathyroid_gland1.40371041
41MP0009333_abnormal_splenocyte_physiolog1.37944486
42MP0001800_abnormal_humoral_immune1.25016735
43MP0009697_abnormal_copulation1.24723176
44MP0002210_abnormal_sex_determination1.24349500
45MP0005389_reproductive_system_phenotype1.23314186
46MP0000465_gastrointestinal_hemorrhage1.22988889
47MP0008932_abnormal_embryonic_tissue1.17069606
48MP0005084_abnormal_gallbladder_morpholo1.13162111
49MP0002148_abnormal_hypersensitivity_rea1.11313039
50MP0003718_maternal_effect1.05651452
51MP0006072_abnormal_retinal_apoptosis1.05598188
52MP0006035_abnormal_mitochondrial_morpho1.03579707
53MP0004142_abnormal_muscle_tone0.99884746
54MP0003937_abnormal_limbs/digits/tail_de0.97978255
55MP0001145_abnormal_male_reproductive0.97739695
56MP0003959_abnormal_lean_body0.96273181
57MP0000049_abnormal_middle_ear0.93761381
58MP0002132_abnormal_respiratory_system0.90861421
59MP0001881_abnormal_mammary_gland0.90685579
60MP0004782_abnormal_surfactant_physiolog0.88487655
61MP0000653_abnormal_sex_gland0.87789182
62MP0005000_abnormal_immune_tolerance0.86163796
63MP0001929_abnormal_gametogenesis0.85450619
64MP0002735_abnormal_chemical_nociception0.85057782
65MP0001919_abnormal_reproductive_system0.83516146
66MP0005166_decreased_susceptibility_to0.83051245
67MP0000372_irregular_coat_pigmentation0.83036345
68MP0001764_abnormal_homeostasis0.82277182
69MP0003045_fibrosis0.81320335
70MP0001879_abnormal_lymphatic_vessel0.80136913
71MP0002398_abnormal_bone_marrow0.76636169
72MP0003656_abnormal_erythrocyte_physiolo0.75206287
73MP0005636_abnormal_mineral_homeostasis0.73889542
74MP0001663_abnormal_digestive_system0.73857620
75MP0002693_abnormal_pancreas_physiology0.70876475
76MP0001188_hyperpigmentation0.70810746
77MP0003137_abnormal_impulse_conducting0.69768433
78MP0001697_abnormal_embryo_size0.67824230
79MP0000313_abnormal_cell_death0.66860711
80MP0002723_abnormal_immune_serum0.64594718
81MP0002429_abnormal_blood_cell0.63451866
82MP0003646_muscle_fatigue0.62706551
83MP0002420_abnormal_adaptive_immunity0.60864157
84MP0001819_abnormal_immune_cell0.59336575
85MP0002452_abnormal_antigen_presenting0.58987630
86MP0005551_abnormal_eye_electrophysiolog0.57327987
87MP0002084_abnormal_developmental_patter0.57274985
88MP0008789_abnormal_olfactory_epithelium0.57220925
89MP0000467_abnormal_esophagus_morphology0.56879188
90MP0003936_abnormal_reproductive_system0.54890846
91MP0001119_abnormal_female_reproductive0.54538278
92MP0004084_abnormal_cardiac_muscle0.54157747
93MP0000716_abnormal_immune_system0.53157599
94MP0006276_abnormal_autonomic_nervous0.50455183
95MP0000604_amyloidosis0.50138705
96MP0002127_abnormal_cardiovascular_syste0.49421768
97MP0000490_abnormal_crypts_of0.49229876
98MP0000477_abnormal_intestine_morphology0.48305320
99MP0000681_abnormal_thyroid_gland0.47924138
100MP0002138_abnormal_hepatobiliary_system0.47553917

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.99696359
2Abnormal mitochondria in muscle tissue (HP:0008316)4.40262141
3Increased CSF lactate (HP:0002490)4.34811707
4Increased hepatocellular lipid droplets (HP:0006565)4.33516976
5Acute encephalopathy (HP:0006846)4.29892527
6Lipid accumulation in hepatocytes (HP:0006561)4.24246962
7Birth length less than 3rd percentile (HP:0003561)4.22975249
8Mitochondrial inheritance (HP:0001427)4.15039461
9Stenosis of the external auditory canal (HP:0000402)4.07910420
10Progressive macrocephaly (HP:0004481)4.03203546
11Reticulocytopenia (HP:0001896)3.90758259
12Abnormality of cells of the erythroid lineage (HP:0012130)3.71885209
13Hepatocellular necrosis (HP:0001404)3.55620881
14Degeneration of anterior horn cells (HP:0002398)3.36659011
15Abnormality of the anterior horn cell (HP:0006802)3.36659011
16Increased serum lactate (HP:0002151)3.32931421
17Decreased activity of mitochondrial respiratory chain (HP:0008972)3.29408881
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.29408881
19Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.24598464
20Horseshoe kidney (HP:0000085)3.01969394
21Congenital, generalized hypertrichosis (HP:0004540)3.00278575
22Exertional dyspnea (HP:0002875)2.98261507
23Aplasia/Hypoplasia of the spleen (HP:0010451)2.97661158
24Pallor (HP:0000980)2.93716785
25Microvesicular hepatic steatosis (HP:0001414)2.92362723
26Macrocytic anemia (HP:0001972)2.91436998
27Asplenia (HP:0001746)2.88588888
28Colon cancer (HP:0003003)2.88411962
29Paralysis (HP:0003470)2.87323834
30Abnormality of incisor morphology (HP:0011063)2.87264964
31Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.84573291
32Type I transferrin isoform profile (HP:0003642)2.84017011
33Cerebral edema (HP:0002181)2.83408193
34Cerebral hypomyelination (HP:0006808)2.82252668
35Abnormality of cochlea (HP:0000375)2.76488599
36Increased serum pyruvate (HP:0003542)2.73633569
37Respiratory failure (HP:0002878)2.73029895
38Hepatic necrosis (HP:0002605)2.72038767
39Abnormality of the renal collecting system (HP:0004742)2.67875245
40Absent rod-and cone-mediated responses on ERG (HP:0007688)2.65371395
41Aplastic anemia (HP:0001915)2.63030943
42Cerebral hemorrhage (HP:0001342)2.58371277
43Chromsome breakage (HP:0040012)2.55586604
44Lactic acidosis (HP:0003128)2.52174228
45Chronic sinusitis (HP:0011109)2.50610519
46Optic disc pallor (HP:0000543)2.46846370
47Agnosia (HP:0010524)2.46124701
48Absent thumb (HP:0009777)2.45976820
49Increased intramyocellular lipid droplets (HP:0012240)2.45779970
50Renal Fanconi syndrome (HP:0001994)2.45026618
51Chromosomal breakage induced by crosslinking agents (HP:0003221)2.42952382
52Neoplasm of the peripheral nervous system (HP:0100007)2.34383410
53Exercise intolerance (HP:0003546)2.33168702
54Bilateral sensorineural hearing impairment (HP:0008619)2.32526073
55Absent/shortened dynein arms (HP:0200106)2.30889578
56Dynein arm defect of respiratory motile cilia (HP:0012255)2.30889578
57Fatigue (HP:0012378)2.30041992
58Leukodystrophy (HP:0002415)2.25081292
59Abnormal number of erythroid precursors (HP:0012131)2.24139692
60Increased muscle lipid content (HP:0009058)2.23650815
61Febrile seizures (HP:0002373)2.17050311
62Intrahepatic cholestasis (HP:0001406)2.13478863
63CNS demyelination (HP:0007305)2.12643393
64Small hand (HP:0200055)2.11839912
65Oral leukoplakia (HP:0002745)2.11632815
66Premature ovarian failure (HP:0008209)2.11047952
67Ependymoma (HP:0002888)2.08916553
68Lethargy (HP:0001254)2.06757902
69Pancytopenia (HP:0001876)2.05502977
70Morphological abnormality of the inner ear (HP:0011390)2.02422093
71Spinal muscular atrophy (HP:0007269)2.02183931
72Respiratory difficulties (HP:0002880)2.02140513
73Abnormal ciliary motility (HP:0012262)2.00089747
74IgG deficiency (HP:0004315)1.99003577
75Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.98223406
76Pendular nystagmus (HP:0012043)1.96850536
77Congenital ichthyosiform erythroderma (HP:0007431)1.95735897
78Abnormality of glycolysis (HP:0004366)1.94842035
79Testicular atrophy (HP:0000029)1.92950771
80Tetany (HP:0001281)1.92279693
81Sensorimotor neuropathy (HP:0007141)1.89404844
82Aplasia/Hypoplasia of the ulna (HP:0006495)1.87285096
833-Methylglutaconic aciduria (HP:0003535)1.86912750
84Constricted visual fields (HP:0001133)1.86858399
85Hypomagnesemia (HP:0002917)1.85848025
86Hypoplasia of the ulna (HP:0003022)1.85784882
87Abnormal respiratory motile cilium morphology (HP:0005938)1.85438971
88Abnormal respiratory epithelium morphology (HP:0012253)1.85438971
89Dry hair (HP:0011359)1.84416112
90Ectopic kidney (HP:0000086)1.83921966
91Severe combined immunodeficiency (HP:0004430)1.82615007
92Duplicated collecting system (HP:0000081)1.76799221
93Meckel diverticulum (HP:0002245)1.76777003
94Agammaglobulinemia (HP:0004432)1.76696865
95Short 1st metacarpal (HP:0010034)1.74472146
96Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.74472146
97Combined immunodeficiency (HP:0005387)1.73565953
98Hypergonadotropic hypogonadism (HP:0000815)1.73388782
99Emotional lability (HP:0000712)1.73022291
100Limb hypertonia (HP:0002509)1.72220399

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK165.36941114
2MST45.35973768
3PBK4.54579090
4SRPK13.06885591
5PLK42.68370556
6NEK12.65632506
7BMPR22.60160084
8WEE12.56746677
9CCNB12.51373160
10EIF2AK12.44408032
11MAP3K122.37118914
12STK242.10068904
13STK38L2.02072809
14TEC1.92511508
15CDK81.75632805
16TAOK31.70652082
17BRSK21.69272849
18PASK1.66627722
19DYRK31.65139937
20RIPK41.53056641
21MATK1.50931958
22TTK1.44699283
23RPS6KB21.39602060
24BRAF1.36741988
25CDK191.31226527
26NEK21.26118395
27PLK11.25184041
28NME11.23352829
29PDK21.20603716
30PAK41.19668082
31BRSK11.19490049
32ILK1.19237732
33NME21.09774252
34DAPK31.06232650
35ITK1.05979986
36PIK3CA1.03728039
37MYLK1.02525132
38STK391.01318142
39EIF2AK31.01103095
40VRK11.00032519
41DAPK20.98843969
42TSSK60.95916608
43AURKB0.95559711
44TIE10.94127996
45ADRBK20.91034684
46ERBB30.90393999
47PIK3CG0.89989244
48DAPK10.89861323
49DYRK20.85788931
50PLK30.85177041
51VRK20.84620461
52BRD40.83013687
53CDC70.81290332
54GRK10.81285630
55WNK40.81161998
56STK30.79632160
57KIT0.72125242
58DYRK1A0.67965429
59CDK40.66419912
60AURKA0.61770349
61STK40.61602471
62CSNK2A20.59667905
63AKT30.57210669
64INSRR0.55467244
65SYK0.54699490
66EGFR0.54603266
67CSNK2A10.54078481
68PRKCE0.51365084
69FGFR30.50823445
70BUB10.50512204
71TAF10.47083011
72BTK0.46941381
73PRKCH0.46743042
74ATR0.46140137
75NUAK10.46112542
76TESK20.45605412
77OXSR10.44373724
78CHEK20.44338405
79LYN0.43295077
80CSK0.43013407
81TGFBR10.39557894
82MKNK20.39097546
83WNK10.35495848
84TYK20.34498433
85INSR0.34182924
86TLK10.33614739
87PIM10.32194992
88TYRO30.31933505
89OBSCN0.31253675
90LRRK20.31026325
91ATM0.30824618
92RPS6KA10.30564748
93IGF1R0.30030809
94CHEK10.29075152
95MKNK10.28091163
96LCK0.27805522
97ZAK0.26270327
98CDK10.25916045
99TRPM70.22941677
100IKBKB0.22037484

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.71914170
2Asthma_Homo sapiens_hsa053104.44397741
3Proteasome_Homo sapiens_hsa030503.78659646
4Allograft rejection_Homo sapiens_hsa053303.33760375
5Autoimmune thyroid disease_Homo sapiens_hsa053203.20289960
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.95834743
7DNA replication_Homo sapiens_hsa030302.74212158
8Oxidative phosphorylation_Homo sapiens_hsa001902.58828281
9Protein export_Homo sapiens_hsa030602.57834437
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.56823804
11Base excision repair_Homo sapiens_hsa034102.47792681
12Mismatch repair_Homo sapiens_hsa034302.35821007
13Nucleotide excision repair_Homo sapiens_hsa034202.33818989
14RNA polymerase_Homo sapiens_hsa030202.23495883
15Homologous recombination_Homo sapiens_hsa034402.20681504
16Basal transcription factors_Homo sapiens_hsa030222.07120594
17Parkinsons disease_Homo sapiens_hsa050122.04733411
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.73564933
19Graft-versus-host disease_Homo sapiens_hsa053321.71314666
20Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.70929086
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.69698237
22Type I diabetes mellitus_Homo sapiens_hsa049401.52943529
23RNA degradation_Homo sapiens_hsa030181.52153777
24Fanconi anemia pathway_Homo sapiens_hsa034601.51962971
25Huntingtons disease_Homo sapiens_hsa050161.49539587
26Pyrimidine metabolism_Homo sapiens_hsa002401.45521514
27Spliceosome_Homo sapiens_hsa030401.44524752
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.42791938
29Vitamin B6 metabolism_Homo sapiens_hsa007501.41389879
30RNA transport_Homo sapiens_hsa030131.40884364
31Folate biosynthesis_Homo sapiens_hsa007901.36417757
32Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.34075625
33Non-homologous end-joining_Homo sapiens_hsa034501.30400826
34Cardiac muscle contraction_Homo sapiens_hsa042601.30094644
35Alzheimers disease_Homo sapiens_hsa050101.25825277
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15092284
37Sulfur relay system_Homo sapiens_hsa041221.10848959
38One carbon pool by folate_Homo sapiens_hsa006701.04969026
39Hematopoietic cell lineage_Homo sapiens_hsa046401.03185515
40Primary immunodeficiency_Homo sapiens_hsa053401.02001620
41mRNA surveillance pathway_Homo sapiens_hsa030151.01931979
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.97649725
43Cell cycle_Homo sapiens_hsa041100.92401383
44Rheumatoid arthritis_Homo sapiens_hsa053230.90819630
45Primary bile acid biosynthesis_Homo sapiens_hsa001200.89073223
46Purine metabolism_Homo sapiens_hsa002300.88476477
47Regulation of autophagy_Homo sapiens_hsa041400.83581978
48Drug metabolism - other enzymes_Homo sapiens_hsa009830.81787805
49Caffeine metabolism_Homo sapiens_hsa002320.79047313
50Propanoate metabolism_Homo sapiens_hsa006400.74702887
51Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72413524
52Cysteine and methionine metabolism_Homo sapiens_hsa002700.68271676
53Collecting duct acid secretion_Homo sapiens_hsa049660.66850617
54Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.64836923
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.63987548
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63969710
57Steroid biosynthesis_Homo sapiens_hsa001000.63036217
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56233792
59Jak-STAT signaling pathway_Homo sapiens_hsa046300.54957584
60Oocyte meiosis_Homo sapiens_hsa041140.53867339
61TGF-beta signaling pathway_Homo sapiens_hsa043500.52905085
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52852371
63Maturity onset diabetes of the young_Homo sapiens_hsa049500.51356143
64Olfactory transduction_Homo sapiens_hsa047400.46034578
65Linoleic acid metabolism_Homo sapiens_hsa005910.45828560
66Retinol metabolism_Homo sapiens_hsa008300.44045994
67Legionellosis_Homo sapiens_hsa051340.42585208
68Vitamin digestion and absorption_Homo sapiens_hsa049770.42328047
69Epstein-Barr virus infection_Homo sapiens_hsa051690.41483100
70Starch and sucrose metabolism_Homo sapiens_hsa005000.40233144
71Steroid hormone biosynthesis_Homo sapiens_hsa001400.39020705
72Metabolic pathways_Homo sapiens_hsa011000.37858382
73Peroxisome_Homo sapiens_hsa041460.33544872
74Chemical carcinogenesis_Homo sapiens_hsa052040.33407701
75Pyruvate metabolism_Homo sapiens_hsa006200.33389920
76Antigen processing and presentation_Homo sapiens_hsa046120.32637492
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32447444
78Phototransduction_Homo sapiens_hsa047440.28787552
79Leishmaniasis_Homo sapiens_hsa051400.28308076
80Nitrogen metabolism_Homo sapiens_hsa009100.25292999
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23056776
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.23038141
83Viral myocarditis_Homo sapiens_hsa054160.22551914
84N-Glycan biosynthesis_Homo sapiens_hsa005100.21003042
85T cell receptor signaling pathway_Homo sapiens_hsa046600.20448284
86Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.20272737
87Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.16245158
88Long-term depression_Homo sapiens_hsa047300.15129680
89Fatty acid degradation_Homo sapiens_hsa000710.14221717
90Systemic lupus erythematosus_Homo sapiens_hsa053220.13699806
91Pancreatic secretion_Homo sapiens_hsa049720.13422613
92alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.10922047
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.08116876
94Arachidonic acid metabolism_Homo sapiens_hsa005900.07822251
95Carbon metabolism_Homo sapiens_hsa012000.07484766
96PI3K-Akt signaling pathway_Homo sapiens_hsa041510.06394951
97Mineral absorption_Homo sapiens_hsa049780.05969195
98Staphylococcus aureus infection_Homo sapiens_hsa051500.04648789
99Measles_Homo sapiens_hsa051620.03869122
100HTLV-I infection_Homo sapiens_hsa051660.03449273

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »