

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 8.19935097 |
| 2 | positive regulation of interleukin-17 production (GO:0032740) | 5.89746481 |
| 3 | ribosomal large subunit biogenesis (GO:0042273) | 5.71394603 |
| 4 | viral transcription (GO:0019083) | 5.66866979 |
| 5 | translational termination (GO:0006415) | 5.46408256 |
| 6 | drinking behavior (GO:0042756) | 4.95680096 |
| 7 | translational elongation (GO:0006414) | 4.80590928 |
| 8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.76028945 |
| 9 | cotranslational protein targeting to membrane (GO:0006613) | 4.67776302 |
| 10 | ribosomal small subunit biogenesis (GO:0042274) | 4.62037830 |
| 11 | protein targeting to ER (GO:0045047) | 4.60241464 |
| 12 | cellular response to ATP (GO:0071318) | 4.55790306 |
| 13 | maturation of SSU-rRNA (GO:0030490) | 4.54155101 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.42422121 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 4.37168751 |
| 16 | cellular ketone body metabolic process (GO:0046950) | 4.20269686 |
| 17 | behavioral response to nicotine (GO:0035095) | 4.19527219 |
| 18 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.14657716 |
| 19 | viral life cycle (GO:0019058) | 4.08861403 |
| 20 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.08365361 |
| 21 | DNA deamination (GO:0045006) | 4.05930748 |
| 22 | cellular protein complex disassembly (GO:0043624) | 4.01875742 |
| 23 | translational initiation (GO:0006413) | 4.00255134 |
| 24 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.95358298 |
| 25 | grooming behavior (GO:0007625) | 3.94902477 |
| 26 | cell wall macromolecule metabolic process (GO:0044036) | 3.91836840 |
| 27 | negative regulation of appetite (GO:0032099) | 3.89613017 |
| 28 | negative regulation of response to food (GO:0032096) | 3.89613017 |
| 29 | regulation of immunoglobulin secretion (GO:0051023) | 3.88244095 |
| 30 | regulation of feeding behavior (GO:0060259) | 3.73660148 |
| 31 | ketone body metabolic process (GO:1902224) | 3.72322027 |
| 32 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.67636498 |
| 33 | negative regulation of digestive system process (GO:0060457) | 3.62293554 |
| 34 | positive regulation of vascular permeability (GO:0043117) | 3.59839291 |
| 35 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.51775078 |
| 36 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.47177379 |
| 37 | translation (GO:0006412) | 3.43840506 |
| 38 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.40438094 |
| 39 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.38475498 |
| 40 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.33114460 |
| 41 | phosphate ion homeostasis (GO:0055062) | 3.32322021 |
| 42 | trivalent inorganic anion homeostasis (GO:0072506) | 3.32322021 |
| 43 | regulation of interleukin-17 production (GO:0032660) | 3.30231069 |
| 44 | hormone catabolic process (GO:0042447) | 3.22361076 |
| 45 | ncRNA 3-end processing (GO:0043628) | 3.21616296 |
| 46 | purine nucleotide salvage (GO:0032261) | 3.20963142 |
| 47 | positive regulation of DNA recombination (GO:0045911) | 3.19386128 |
| 48 | protein complex disassembly (GO:0043241) | 3.16120593 |
| 49 | regulation of regulatory T cell differentiation (GO:0045589) | 3.15498779 |
| 50 | carnitine transmembrane transport (GO:1902603) | 3.12581208 |
| 51 | positive regulation of digestive system process (GO:0060456) | 3.09074752 |
| 52 | cellular component biogenesis (GO:0044085) | 3.08321905 |
| 53 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.07903890 |
| 54 | macromolecular complex disassembly (GO:0032984) | 3.04407211 |
| 55 | amino-acid betaine transport (GO:0015838) | 3.02262031 |
| 56 | carnitine transport (GO:0015879) | 3.02262031 |
| 57 | labyrinthine layer development (GO:0060711) | 2.99389412 |
| 58 | chaperone-mediated protein transport (GO:0072321) | 2.97986115 |
| 59 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.95981792 |
| 60 | positive regulation of isotype switching (GO:0045830) | 2.94271851 |
| 61 | organic cation transport (GO:0015695) | 2.92455580 |
| 62 | regulation of appetite (GO:0032098) | 2.92198062 |
| 63 | mRNA catabolic process (GO:0006402) | 2.91776565 |
| 64 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.90795790 |
| 65 | response to pheromone (GO:0019236) | 2.89577405 |
| 66 | protein neddylation (GO:0045116) | 2.89203036 |
| 67 | aggressive behavior (GO:0002118) | 2.88180585 |
| 68 | purine-containing compound salvage (GO:0043101) | 2.84648332 |
| 69 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.82401582 |
| 70 | male meiosis I (GO:0007141) | 2.81394687 |
| 71 | protein targeting to membrane (GO:0006612) | 2.80712879 |
| 72 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.74969634 |
| 73 | NADH dehydrogenase complex assembly (GO:0010257) | 2.74969634 |
| 74 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.74969634 |
| 75 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.71490698 |
| 76 | ATP synthesis coupled proton transport (GO:0015986) | 2.71490698 |
| 77 | piRNA metabolic process (GO:0034587) | 2.68893709 |
| 78 | protein complex biogenesis (GO:0070271) | 2.67628970 |
| 79 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.65317417 |
| 80 | positive regulation of cell fate commitment (GO:0010455) | 2.64003469 |
| 81 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.63774115 |
| 82 | RNA catabolic process (GO:0006401) | 2.61529991 |
| 83 | negative regulation of B cell apoptotic process (GO:0002903) | 2.61054566 |
| 84 | glucosamine-containing compound catabolic process (GO:1901072) | 2.59507776 |
| 85 | determination of adult lifespan (GO:0008340) | 2.59069081 |
| 86 | interferon-gamma production (GO:0032609) | 2.59017505 |
| 87 | rRNA processing (GO:0006364) | 2.57657754 |
| 88 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.57368135 |
| 89 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.56631103 |
| 90 | rRNA metabolic process (GO:0016072) | 2.53810228 |
| 91 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.49358159 |
| 92 | detection of light stimulus involved in visual perception (GO:0050908) | 2.49358159 |
| 93 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.49053426 |
| 94 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.46716033 |
| 95 | aldehyde catabolic process (GO:0046185) | 2.45885626 |
| 96 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.44771911 |
| 97 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.43957001 |
| 98 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.43957001 |
| 99 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.42943301 |
| 100 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.42943301 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.86809297 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.41450935 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.37236386 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.26770247 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.25927082 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.16812285 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.93233834 |
| 8 | GATA1_22025678_ChIP-Seq_K562_Human | 2.89788806 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.69172888 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.46918329 |
| 11 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.26203309 |
| 12 | EWS_26573619_Chip-Seq_HEK293_Human | 2.14863326 |
| 13 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.12402446 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.99797605 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.96861845 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 1.95918159 |
| 17 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.94190651 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.93512545 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.90214436 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.88185200 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.88118366 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.70543017 |
| 23 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.68958321 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.68789923 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66296203 |
| 26 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.65006800 |
| 27 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.65006800 |
| 28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.57977391 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.55356051 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.54113135 |
| 31 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.54097152 |
| 32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.53053611 |
| 33 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.53000349 |
| 34 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.49090782 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.48092678 |
| 36 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.47962931 |
| 37 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.44973694 |
| 38 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.44469169 |
| 39 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.44469169 |
| 40 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.43893220 |
| 41 | NCOR_22424771_ChIP-Seq_293T_Human | 1.43700426 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.43179814 |
| 43 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.43017169 |
| 44 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.41540180 |
| 45 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.41357197 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.39824236 |
| 47 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.37141947 |
| 48 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.36244563 |
| 49 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.35734960 |
| 50 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.33032894 |
| 51 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.32579099 |
| 52 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.31787708 |
| 53 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.31787708 |
| 54 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29492837 |
| 55 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28109671 |
| 56 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.27730629 |
| 57 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26750293 |
| 58 | GATA3_26560356_Chip-Seq_TH2_Human | 1.26516538 |
| 59 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26178194 |
| 60 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.25552906 |
| 61 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.22011227 |
| 62 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.21132486 |
| 63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20669586 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.16542464 |
| 65 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.16262345 |
| 66 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.14188456 |
| 67 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.12819938 |
| 68 | P300_19829295_ChIP-Seq_ESCs_Human | 1.11864961 |
| 69 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11510426 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10799331 |
| 71 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.10303351 |
| 72 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.09708263 |
| 73 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.07505031 |
| 74 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.04314855 |
| 75 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.02833607 |
| 76 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.01534556 |
| 77 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.99772978 |
| 78 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.99729983 |
| 79 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.99221290 |
| 80 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.99098126 |
| 81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.98502446 |
| 82 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98201220 |
| 83 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.95980272 |
| 84 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95723123 |
| 85 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.95554970 |
| 86 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.93781465 |
| 87 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.93598297 |
| 88 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.92996144 |
| 89 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.92977935 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.92147278 |
| 91 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.90364031 |
| 92 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.89824675 |
| 93 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89323726 |
| 94 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.89166467 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.88986223 |
| 96 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.88901043 |
| 97 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.88410003 |
| 98 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.88220498 |
| 99 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.87817242 |
| 100 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.86906433 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.24706055 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.35018702 |
| 3 | MP0000678_abnormal_parathyroid_gland | 2.95380017 |
| 4 | MP0005084_abnormal_gallbladder_morpholo | 2.53095243 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.34883373 |
| 6 | MP0003646_muscle_fatigue | 2.17692829 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 2.17538557 |
| 8 | MP0008872_abnormal_physiological_respon | 2.16367464 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.10073972 |
| 10 | MP0004147_increased_porphyrin_level | 2.03514802 |
| 11 | MP0001188_hyperpigmentation | 1.95860434 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 1.93576060 |
| 13 | MP0005389_reproductive_system_phenotype | 1.92273711 |
| 14 | MP0005551_abnormal_eye_electrophysiolog | 1.91619884 |
| 15 | MP0008995_early_reproductive_senescence | 1.88352404 |
| 16 | MP0006292_abnormal_olfactory_placode | 1.88110282 |
| 17 | MP0005075_abnormal_melanosome_morpholog | 1.87143092 |
| 18 | MP0002396_abnormal_hematopoietic_system | 1.83232396 |
| 19 | MP0003567_abnormal_fetal_cardiomyocyte | 1.82273815 |
| 20 | MP0002160_abnormal_reproductive_system | 1.80546944 |
| 21 | MP0001529_abnormal_vocalization | 1.78969981 |
| 22 | MP0001873_stomach_inflammation | 1.76982356 |
| 23 | MP0009333_abnormal_splenocyte_physiolog | 1.75153398 |
| 24 | MP0005387_immune_system_phenotype | 1.66696961 |
| 25 | MP0001790_abnormal_immune_system | 1.66696961 |
| 26 | MP0001986_abnormal_taste_sensitivity | 1.63775794 |
| 27 | MP0001919_abnormal_reproductive_system | 1.61922584 |
| 28 | MP0003786_premature_aging | 1.61649033 |
| 29 | MP0005671_abnormal_response_to | 1.52995891 |
| 30 | MP0001485_abnormal_pinna_reflex | 1.51878802 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.48579930 |
| 32 | MP0002837_dystrophic_cardiac_calcinosis | 1.43986080 |
| 33 | MP0003806_abnormal_nucleotide_metabolis | 1.43296984 |
| 34 | MP0002735_abnormal_chemical_nociception | 1.43147383 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.42445540 |
| 36 | MP0001348_abnormal_lacrimal_gland | 1.38592698 |
| 37 | MP0010386_abnormal_urinary_bladder | 1.38094327 |
| 38 | MP0003195_calcinosis | 1.36978002 |
| 39 | MP0003283_abnormal_digestive_organ | 1.32592311 |
| 40 | MP0003252_abnormal_bile_duct | 1.28797476 |
| 41 | MP0000685_abnormal_immune_system | 1.21257536 |
| 42 | MP0006276_abnormal_autonomic_nervous | 1.19119115 |
| 43 | MP0000383_abnormal_hair_follicle | 1.19100880 |
| 44 | MP0000372_irregular_coat_pigmentation | 1.18895464 |
| 45 | MP0005085_abnormal_gallbladder_physiolo | 1.18249379 |
| 46 | MP0001800_abnormal_humoral_immune | 1.16920014 |
| 47 | MP0004484_altered_response_of | 1.15085911 |
| 48 | MP0005646_abnormal_pituitary_gland | 1.13328359 |
| 49 | MP0008875_abnormal_xenobiotic_pharmacok | 1.12743161 |
| 50 | MP0000604_amyloidosis | 1.12354034 |
| 51 | MP0005000_abnormal_immune_tolerance | 1.10586416 |
| 52 | MP0004142_abnormal_muscle_tone | 1.09514579 |
| 53 | MP0000013_abnormal_adipose_tissue | 1.04207626 |
| 54 | MP0002102_abnormal_ear_morphology | 1.00997872 |
| 55 | MP0002876_abnormal_thyroid_physiology | 1.00977418 |
| 56 | MP0004885_abnormal_endolymph | 1.00676497 |
| 57 | MP0005636_abnormal_mineral_homeostasis | 0.99252671 |
| 58 | MP0009785_altered_susceptibility_to | 0.98554611 |
| 59 | MP0004145_abnormal_muscle_electrophysio | 0.97231182 |
| 60 | MP0002405_respiratory_system_inflammati | 0.96278580 |
| 61 | MP0001664_abnormal_digestion | 0.96145559 |
| 62 | MP0005025_abnormal_response_to | 0.95899115 |
| 63 | MP0000631_abnormal_neuroendocrine_gland | 0.95475442 |
| 64 | MP0002723_abnormal_immune_serum | 0.95126655 |
| 65 | MP0001905_abnormal_dopamine_level | 0.95042185 |
| 66 | MP0001765_abnormal_ion_homeostasis | 0.94339966 |
| 67 | MP0001764_abnormal_homeostasis | 0.94305001 |
| 68 | MP0006036_abnormal_mitochondrial_physio | 0.93869330 |
| 69 | MP0001440_abnormal_grooming_behavior | 0.91787103 |
| 70 | MP0004215_abnormal_myocardial_fiber | 0.91480847 |
| 71 | MP0002127_abnormal_cardiovascular_syste | 0.89543469 |
| 72 | MP0002693_abnormal_pancreas_physiology | 0.89447402 |
| 73 | MP0003878_abnormal_ear_physiology | 0.86760755 |
| 74 | MP0005377_hearing/vestibular/ear_phenot | 0.86760755 |
| 75 | MP0006082_CNS_inflammation | 0.85256725 |
| 76 | MP0005253_abnormal_eye_physiology | 0.85219275 |
| 77 | MP0000230_abnormal_systemic_arterial | 0.84473356 |
| 78 | MP0004742_abnormal_vestibular_system | 0.82871490 |
| 79 | MP0002420_abnormal_adaptive_immunity | 0.82746658 |
| 80 | MP0002272_abnormal_nervous_system | 0.82172280 |
| 81 | MP0002234_abnormal_pharynx_morphology | 0.81937545 |
| 82 | MP0001963_abnormal_hearing_physiology | 0.81776572 |
| 83 | MP0002398_abnormal_bone_marrow | 0.81770460 |
| 84 | MP0009643_abnormal_urine_homeostasis | 0.80376757 |
| 85 | MP0001663_abnormal_digestive_system | 0.79831812 |
| 86 | MP0001819_abnormal_immune_cell | 0.79464073 |
| 87 | MP0003866_abnormal_defecation | 0.79205883 |
| 88 | MP0003936_abnormal_reproductive_system | 0.79025765 |
| 89 | MP0002095_abnormal_skin_pigmentation | 0.78975445 |
| 90 | MP0005464_abnormal_platelet_physiology | 0.77276334 |
| 91 | MP0000716_abnormal_immune_system | 0.76790662 |
| 92 | MP0000049_abnormal_middle_ear | 0.76001395 |
| 93 | MP0003959_abnormal_lean_body | 0.74777690 |
| 94 | MP0001486_abnormal_startle_reflex | 0.73571075 |
| 95 | MP0005332_abnormal_amino_acid | 0.72545501 |
| 96 | MP0002452_abnormal_antigen_presenting | 0.70771701 |
| 97 | MP0001881_abnormal_mammary_gland | 0.70493316 |
| 98 | MP0002163_abnormal_gland_morphology | 0.69089844 |
| 99 | MP0005410_abnormal_fertilization | 0.67866093 |
| 100 | MP0009745_abnormal_behavioral_response | 0.67523348 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Generalized aminoaciduria (HP:0002909) | 4.69139558 |
| 2 | Renal Fanconi syndrome (HP:0001994) | 3.97962665 |
| 3 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.81132318 |
| 4 | Abnormality of B cell number (HP:0010975) | 3.71644859 |
| 5 | B lymphocytopenia (HP:0010976) | 3.61911439 |
| 6 | Abnormality of the costochondral junction (HP:0000919) | 3.60869080 |
| 7 | Reticulocytopenia (HP:0001896) | 3.55143986 |
| 8 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.49270578 |
| 9 | Tetany (HP:0001281) | 3.46010949 |
| 10 | Stomatitis (HP:0010280) | 3.44721154 |
| 11 | Hyperglycinemia (HP:0002154) | 3.43120477 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.40294319 |
| 13 | Decreased central vision (HP:0007663) | 3.31898564 |
| 14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.25017873 |
| 15 | Stenosis of the external auditory canal (HP:0000402) | 3.23809619 |
| 16 | Abnormal drinking behavior (HP:0030082) | 3.19796009 |
| 17 | Polydipsia (HP:0001959) | 3.19796009 |
| 18 | Macrocytic anemia (HP:0001972) | 3.10378608 |
| 19 | Methylmalonic acidemia (HP:0002912) | 3.08500500 |
| 20 | Pendular nystagmus (HP:0012043) | 3.06511369 |
| 21 | Congenital stationary night blindness (HP:0007642) | 3.06205552 |
| 22 | Abnormality of urine glucose concentration (HP:0011016) | 2.91498592 |
| 23 | Glycosuria (HP:0003076) | 2.91498592 |
| 24 | Attenuation of retinal blood vessels (HP:0007843) | 2.87099780 |
| 25 | Failure to thrive in infancy (HP:0001531) | 2.83820644 |
| 26 | Increased IgM level (HP:0003496) | 2.83787633 |
| 27 | Type 2 muscle fiber atrophy (HP:0003554) | 2.82080216 |
| 28 | Pancreatic cysts (HP:0001737) | 2.80501682 |
| 29 | Abnormal number of erythroid precursors (HP:0012131) | 2.67904609 |
| 30 | Abnormality of serum amino acid levels (HP:0003112) | 2.64903065 |
| 31 | Increased hepatocellular lipid droplets (HP:0006565) | 2.63703165 |
| 32 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.59466966 |
| 33 | Mitochondrial inheritance (HP:0001427) | 2.53094847 |
| 34 | Acute necrotizing encephalopathy (HP:0006965) | 2.52908051 |
| 35 | Pallor (HP:0000980) | 2.52292177 |
| 36 | Lipid accumulation in hepatocytes (HP:0006561) | 2.52008480 |
| 37 | Optic disc pallor (HP:0000543) | 2.52003933 |
| 38 | Abnormality of alanine metabolism (HP:0010916) | 2.50895271 |
| 39 | Hyperalaninemia (HP:0003348) | 2.50895271 |
| 40 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.50895271 |
| 41 | Keratoconus (HP:0000563) | 2.49405069 |
| 42 | Increased corneal curvature (HP:0100692) | 2.49405069 |
| 43 | Metaphyseal dysplasia (HP:0100255) | 2.49274811 |
| 44 | Hypophosphatemic rickets (HP:0004912) | 2.47501694 |
| 45 | Increased CSF lactate (HP:0002490) | 2.46085783 |
| 46 | Polyuria (HP:0000103) | 2.41366734 |
| 47 | Hyperphosphatemia (HP:0002905) | 2.40486116 |
| 48 | Abolished electroretinogram (ERG) (HP:0000550) | 2.38535358 |
| 49 | Recurrent corneal erosions (HP:0000495) | 2.38137609 |
| 50 | Abnormality of renal resorption (HP:0011038) | 2.36436177 |
| 51 | Male infertility (HP:0003251) | 2.35832237 |
| 52 | Methylmalonic aciduria (HP:0012120) | 2.33439763 |
| 53 | Abnormality of DNA repair (HP:0003254) | 2.32689914 |
| 54 | Acute encephalopathy (HP:0006846) | 2.31301437 |
| 55 | Severe combined immunodeficiency (HP:0004430) | 2.29372738 |
| 56 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.28542019 |
| 57 | Muscle fiber atrophy (HP:0100295) | 2.28348237 |
| 58 | Type I transferrin isoform profile (HP:0003642) | 2.24328185 |
| 59 | Progressive macrocephaly (HP:0004481) | 2.18551816 |
| 60 | Abnormal hemoglobin (HP:0011902) | 2.14218108 |
| 61 | Reduced antithrombin III activity (HP:0001976) | 2.13697587 |
| 62 | Abnormality of vitamin B metabolism (HP:0004340) | 2.12868253 |
| 63 | Ketosis (HP:0001946) | 2.11172659 |
| 64 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.10281013 |
| 65 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.09624110 |
| 66 | Constricted visual fields (HP:0001133) | 2.09600691 |
| 67 | True hermaphroditism (HP:0010459) | 2.06520072 |
| 68 | Pancreatic fibrosis (HP:0100732) | 2.04891302 |
| 69 | IgG deficiency (HP:0004315) | 2.03616420 |
| 70 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.00355450 |
| 71 | Neonatal respiratory distress (HP:0002643) | 2.00336388 |
| 72 | Asplenia (HP:0001746) | 1.99583402 |
| 73 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.98236450 |
| 74 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.98236450 |
| 75 | Abnormal protein glycosylation (HP:0012346) | 1.98236450 |
| 76 | Abnormal glycosylation (HP:0012345) | 1.98236450 |
| 77 | Hypoglycemic seizures (HP:0002173) | 1.96852843 |
| 78 | Abnormal urine output (HP:0012590) | 1.96289039 |
| 79 | Type I diabetes mellitus (HP:0100651) | 1.96011027 |
| 80 | Nephronophthisis (HP:0000090) | 1.94256449 |
| 81 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.90729666 |
| 82 | Neutropenia (HP:0001875) | 1.89562930 |
| 83 | Thyroiditis (HP:0100646) | 1.87805771 |
| 84 | Autoimmune thrombocytopenia (HP:0001973) | 1.86641103 |
| 85 | Abnormality of midbrain morphology (HP:0002418) | 1.85879782 |
| 86 | Molar tooth sign on MRI (HP:0002419) | 1.85879782 |
| 87 | Exertional dyspnea (HP:0002875) | 1.85447197 |
| 88 | Increased serum lactate (HP:0002151) | 1.85080782 |
| 89 | Acute lymphatic leukemia (HP:0006721) | 1.84509518 |
| 90 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.83455121 |
| 91 | Focal motor seizures (HP:0011153) | 1.82799655 |
| 92 | Medial flaring of the eyebrow (HP:0010747) | 1.81386319 |
| 93 | Hepatic necrosis (HP:0002605) | 1.79385335 |
| 94 | Aplastic anemia (HP:0001915) | 1.79007055 |
| 95 | Thyroid-stimulating hormone excess (HP:0002925) | 1.76716479 |
| 96 | Congenital hepatic fibrosis (HP:0002612) | 1.76377180 |
| 97 | Genetic anticipation (HP:0003743) | 1.76111416 |
| 98 | Delayed CNS myelination (HP:0002188) | 1.75736627 |
| 99 | Hepatocellular necrosis (HP:0001404) | 1.74085216 |
| 100 | Lethargy (HP:0001254) | 1.73384324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCYL2 | 4.41271380 |
| 2 | TAOK3 | 3.86662079 |
| 3 | PBK | 3.16811038 |
| 4 | FLT3 | 2.87443488 |
| 5 | ZAK | 2.79906373 |
| 6 | BCKDK | 2.64393208 |
| 7 | TXK | 2.53681739 |
| 8 | CDK19 | 2.49369362 |
| 9 | MST4 | 2.45122606 |
| 10 | KIT | 2.31861168 |
| 11 | PRKG2 | 2.27672317 |
| 12 | WNK4 | 2.14569326 |
| 13 | MAP3K12 | 2.13040923 |
| 14 | GRK1 | 2.12217141 |
| 15 | AKT3 | 2.08586062 |
| 16 | ADRBK2 | 2.03741142 |
| 17 | MAP4K1 | 2.01364264 |
| 18 | PASK | 1.89526068 |
| 19 | STK16 | 1.80829655 |
| 20 | RPS6KB2 | 1.77620147 |
| 21 | PIK3CG | 1.73345570 |
| 22 | EIF2AK3 | 1.68980077 |
| 23 | FRK | 1.59384563 |
| 24 | VRK2 | 1.56036400 |
| 25 | TEC | 1.51843953 |
| 26 | ZAP70 | 1.45967805 |
| 27 | DYRK2 | 1.41654147 |
| 28 | NUAK1 | 1.40339776 |
| 29 | MAP2K6 | 1.38715153 |
| 30 | TLK1 | 1.26850002 |
| 31 | IKBKE | 1.20096443 |
| 32 | MAP3K11 | 1.19153198 |
| 33 | STK39 | 1.18964181 |
| 34 | ADRBK1 | 1.16462878 |
| 35 | ITK | 1.12823584 |
| 36 | OXSR1 | 1.08577635 |
| 37 | GRK6 | 1.01997434 |
| 38 | CSF1R | 0.97749432 |
| 39 | VRK1 | 0.97628384 |
| 40 | PLK4 | 0.95835368 |
| 41 | IKBKB | 0.93510719 |
| 42 | NME2 | 0.90726684 |
| 43 | MAP3K6 | 0.88743125 |
| 44 | PIK3CA | 0.87938587 |
| 45 | PRKCQ | 0.87321167 |
| 46 | SYK | 0.86810415 |
| 47 | MAP3K5 | 0.78512467 |
| 48 | KDR | 0.78013943 |
| 49 | MKNK1 | 0.74687359 |
| 50 | LCK | 0.72784278 |
| 51 | PRKCH | 0.72178020 |
| 52 | INSRR | 0.68977006 |
| 53 | BTK | 0.64347043 |
| 54 | MKNK2 | 0.61034041 |
| 55 | NEK1 | 0.60862196 |
| 56 | CCNB1 | 0.59228915 |
| 57 | MAP2K4 | 0.58409686 |
| 58 | TIE1 | 0.57673576 |
| 59 | PDK2 | 0.57670483 |
| 60 | TNIK | 0.56272100 |
| 61 | OBSCN | 0.55083280 |
| 62 | BLK | 0.54673001 |
| 63 | FES | 0.53933313 |
| 64 | GRK7 | 0.53896629 |
| 65 | BMPR2 | 0.53312566 |
| 66 | PRKCE | 0.53120580 |
| 67 | EIF2AK1 | 0.52223126 |
| 68 | MAP2K3 | 0.52073284 |
| 69 | MAPK13 | 0.51651598 |
| 70 | PHKG2 | 0.48855610 |
| 71 | PHKG1 | 0.48855610 |
| 72 | LYN | 0.48800720 |
| 73 | PLK1 | 0.47384709 |
| 74 | MAPKAPK5 | 0.47240168 |
| 75 | LIMK1 | 0.46881177 |
| 76 | CSNK1G3 | 0.46705267 |
| 77 | CSNK2A2 | 0.46593967 |
| 78 | TGFBR1 | 0.46048000 |
| 79 | JAK3 | 0.43518197 |
| 80 | WNK3 | 0.43395035 |
| 81 | PINK1 | 0.42135316 |
| 82 | PRKACA | 0.40797181 |
| 83 | CSNK1A1L | 0.39421030 |
| 84 | RPS6KB1 | 0.39270952 |
| 85 | AURKA | 0.37791613 |
| 86 | TAOK2 | 0.37753855 |
| 87 | MAPKAPK3 | 0.36360943 |
| 88 | CSNK1G1 | 0.35957693 |
| 89 | RPS6KA5 | 0.34710439 |
| 90 | CSK | 0.34403280 |
| 91 | DAPK3 | 0.33281948 |
| 92 | PLK3 | 0.33261045 |
| 93 | CHEK2 | 0.32312676 |
| 94 | NME1 | 0.31978574 |
| 95 | CDK8 | 0.30244154 |
| 96 | PRKCA | 0.29720710 |
| 97 | RPS6KA6 | 0.29227279 |
| 98 | TAF1 | 0.29172257 |
| 99 | TRPM7 | 0.28788829 |
| 100 | CSNK2A1 | 0.28638244 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.22568147 |
| 2 | Asthma_Homo sapiens_hsa05310 | 2.95366638 |
| 3 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.88689850 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.87114148 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.77520454 |
| 6 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.71464097 |
| 7 | Phototransduction_Homo sapiens_hsa04744 | 2.62351232 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.50344631 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.47332815 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.00453362 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.00079065 |
| 12 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.96402493 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.89648081 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.84447319 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.81944728 |
| 16 | Protein export_Homo sapiens_hsa03060 | 1.79996164 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.77774427 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.69562102 |
| 19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.64680271 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.61593193 |
| 21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.49965594 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.49672516 |
| 23 | Olfactory transduction_Homo sapiens_hsa04740 | 1.43290335 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.34824052 |
| 25 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.30830858 |
| 26 | RNA transport_Homo sapiens_hsa03013 | 1.29787202 |
| 27 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.25314467 |
| 28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.23855635 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.21528837 |
| 30 | Homologous recombination_Homo sapiens_hsa03440 | 1.19183037 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.15722071 |
| 32 | Basal transcription factors_Homo sapiens_hsa03022 | 1.15426072 |
| 33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.13303664 |
| 34 | Retinol metabolism_Homo sapiens_hsa00830 | 1.10733516 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.08696461 |
| 36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.06930973 |
| 37 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.00881447 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 0.99994846 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 0.96374938 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.94913774 |
| 41 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.94435871 |
| 42 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.94225305 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.92380789 |
| 44 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.92017274 |
| 45 | Nicotine addiction_Homo sapiens_hsa05033 | 0.91685277 |
| 46 | Mismatch repair_Homo sapiens_hsa03430 | 0.91114786 |
| 47 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.91055467 |
| 48 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.87525410 |
| 49 | Huntingtons disease_Homo sapiens_hsa05016 | 0.87362455 |
| 50 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.86575826 |
| 51 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.86498019 |
| 52 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86278081 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.85416924 |
| 54 | Salivary secretion_Homo sapiens_hsa04970 | 0.84519794 |
| 55 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84372285 |
| 56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.83094559 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.82578128 |
| 58 | Taste transduction_Homo sapiens_hsa04742 | 0.72500466 |
| 59 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.71807947 |
| 60 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.71793871 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.71457741 |
| 62 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.71419938 |
| 63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.71257228 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70187305 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.69715485 |
| 66 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.69278412 |
| 67 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68093011 |
| 68 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.67200106 |
| 69 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.65883632 |
| 70 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.65503840 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.65081020 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64209774 |
| 73 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.59503091 |
| 74 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.58664829 |
| 75 | Renin secretion_Homo sapiens_hsa04924 | 0.57509666 |
| 76 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.54127856 |
| 77 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.52455643 |
| 78 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.52247531 |
| 79 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.50985149 |
| 80 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.50772328 |
| 81 | Measles_Homo sapiens_hsa05162 | 0.49644630 |
| 82 | Base excision repair_Homo sapiens_hsa03410 | 0.48413484 |
| 83 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46111977 |
| 84 | Long-term depression_Homo sapiens_hsa04730 | 0.45446413 |
| 85 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43841610 |
| 86 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41657620 |
| 87 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41536677 |
| 88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40562235 |
| 89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39950975 |
| 90 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.39880567 |
| 91 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39718778 |
| 92 | Spliceosome_Homo sapiens_hsa03040 | 0.37447196 |
| 93 | Circadian entrainment_Homo sapiens_hsa04713 | 0.37263394 |
| 94 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.36737915 |
| 95 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.36491754 |
| 96 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.34378334 |
| 97 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.34091551 |
| 98 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.32725072 |
| 99 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.31949674 |
| 100 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.30342709 |

