

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of sodium ion transport (GO:0010766) | 7.21242781 |
| 2 | regulation of relaxation of muscle (GO:1901077) | 7.06498270 |
| 3 | regulation of cell communication by electrical coupling (GO:0010649) | 6.01674752 |
| 4 | piRNA metabolic process (GO:0034587) | 5.39045047 |
| 5 | relaxation of cardiac muscle (GO:0055119) | 5.33376409 |
| 6 | regulation of action potential (GO:0098900) | 5.31310816 |
| 7 | platelet dense granule organization (GO:0060155) | 4.75048127 |
| 8 | cardiac right ventricle morphogenesis (GO:0003215) | 4.61956235 |
| 9 | synapsis (GO:0007129) | 4.60118819 |
| 10 | regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 4.51833097 |
| 11 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 4.42602987 |
| 12 | regulation of cilium movement (GO:0003352) | 4.31834000 |
| 13 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.27130764 |
| 14 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 4.07836248 |
| 15 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.03451338 |
| 16 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.03451338 |
| 17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.02107936 |
| 18 | NADH dehydrogenase complex assembly (GO:0010257) | 4.02107936 |
| 19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.02107936 |
| 20 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 3.98818688 |
| 21 | sulfation (GO:0051923) | 3.98256724 |
| 22 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.96795028 |
| 23 | response to pheromone (GO:0019236) | 3.93488310 |
| 24 | regulation of DNA-templated transcription, initiation (GO:2000142) | 3.87362907 |
| 25 | renal tubule morphogenesis (GO:0061333) | 3.84711726 |
| 26 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.81155229 |
| 27 | ventricular cardiac muscle cell development (GO:0055015) | 3.71673270 |
| 28 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.70689215 |
| 29 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.66026315 |
| 30 | kidney mesenchyme development (GO:0072074) | 3.65639021 |
| 31 | protein complex biogenesis (GO:0070271) | 3.59747332 |
| 32 | regulation of cofactor metabolic process (GO:0051193) | 3.57990934 |
| 33 | regulation of coenzyme metabolic process (GO:0051196) | 3.57990934 |
| 34 | proteasome assembly (GO:0043248) | 3.53620126 |
| 35 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.49349377 |
| 36 | neurofilament cytoskeleton organization (GO:0060052) | 3.48340841 |
| 37 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.44433688 |
| 38 | acrosome reaction (GO:0007340) | 3.40599892 |
| 39 | relaxation of muscle (GO:0090075) | 3.39067248 |
| 40 | neural tube formation (GO:0001841) | 3.30717558 |
| 41 | protein-cofactor linkage (GO:0018065) | 3.29934643 |
| 42 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.28919885 |
| 43 | keratinocyte development (GO:0003334) | 3.28611754 |
| 44 | serotonin metabolic process (GO:0042428) | 3.28402773 |
| 45 | positive regulation of muscle hypertrophy (GO:0014742) | 3.25431976 |
| 46 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 3.25431976 |
| 47 | metanephric mesenchyme development (GO:0072075) | 3.22729231 |
| 48 | positive regulation of meiosis (GO:0045836) | 3.22449334 |
| 49 | regulation of meiosis I (GO:0060631) | 3.20555537 |
| 50 | DNA methylation involved in gamete generation (GO:0043046) | 3.20399150 |
| 51 | positive regulation of catenin import into nucleus (GO:0035413) | 3.11351465 |
| 52 | phospholipid efflux (GO:0033700) | 3.08778852 |
| 53 | DNA integration (GO:0015074) | 3.07131640 |
| 54 | nephron tubule morphogenesis (GO:0072078) | 3.06028135 |
| 55 | nephron epithelium morphogenesis (GO:0072088) | 3.06028135 |
| 56 | regulation of cholesterol esterification (GO:0010872) | 3.05349415 |
| 57 | maturation of 5.8S rRNA (GO:0000460) | 3.03174405 |
| 58 | positive regulation of meiotic cell cycle (GO:0051446) | 3.02878535 |
| 59 | fatty acid elongation (GO:0030497) | 3.02026505 |
| 60 | phosphorelay signal transduction system (GO:0000160) | 3.00568705 |
| 61 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.97800558 |
| 62 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 2.96589367 |
| 63 | reverse cholesterol transport (GO:0043691) | 2.96550919 |
| 64 | resolution of meiotic recombination intermediates (GO:0000712) | 2.95458253 |
| 65 | cochlea development (GO:0090102) | 2.95199038 |
| 66 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.94808679 |
| 67 | regulation of glucokinase activity (GO:0033131) | 2.92947909 |
| 68 | regulation of hexokinase activity (GO:1903299) | 2.92947909 |
| 69 | regulation of sulfur metabolic process (GO:0042762) | 2.91005803 |
| 70 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 2.90742115 |
| 71 | heme transport (GO:0015886) | 2.90434185 |
| 72 | male meiosis I (GO:0007141) | 2.90403478 |
| 73 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.89422663 |
| 74 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 2.89199391 |
| 75 | gamma-aminobutyric acid transport (GO:0015812) | 2.86893783 |
| 76 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.86748436 |
| 77 | mitochondrial DNA replication (GO:0006264) | 2.83193432 |
| 78 | Notch signaling involved in heart development (GO:0061314) | 2.82180133 |
| 79 | pentose metabolic process (GO:0019321) | 2.81122407 |
| 80 | cellular hyperosmotic response (GO:0071474) | 2.80169488 |
| 81 | regulation of membrane depolarization (GO:0003254) | 2.76488420 |
| 82 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 2.76476232 |
| 83 | cellular ketone body metabolic process (GO:0046950) | 2.76142044 |
| 84 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 2.72598386 |
| 85 | embryonic epithelial tube formation (GO:0001838) | 2.69553127 |
| 86 | protein neddylation (GO:0045116) | 2.68579435 |
| 87 | respiratory chain complex IV assembly (GO:0008535) | 2.67144902 |
| 88 | histone H2A acetylation (GO:0043968) | 2.66319836 |
| 89 | renal absorption (GO:0070293) | 2.65380283 |
| 90 | indolalkylamine metabolic process (GO:0006586) | 2.64450693 |
| 91 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.64281296 |
| 92 | primary amino compound metabolic process (GO:1901160) | 2.63995428 |
| 93 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.62036638 |
| 94 | establishment of integrated proviral latency (GO:0075713) | 2.62032155 |
| 95 | ventricular system development (GO:0021591) | 2.58907201 |
| 96 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 2.55470118 |
| 97 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.54998179 |
| 98 | plasma membrane fusion (GO:0045026) | 2.54929321 |
| 99 | gonadal mesoderm development (GO:0007506) | 2.54030624 |
| 100 | epithelial tube formation (GO:0072175) | 2.52890462 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.74882110 |
| 2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.45672820 |
| 3 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.40535029 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.32240278 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.08693550 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.89191712 |
| 7 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.88697752 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.58378367 |
| 9 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.44055022 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.40977729 |
| 11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.39206515 |
| 12 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.29073060 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.25802034 |
| 14 | P300_19829295_ChIP-Seq_ESCs_Human | 2.20743158 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.08162868 |
| 16 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.05021480 |
| 17 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.00733741 |
| 18 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.99777410 |
| 19 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.99663343 |
| 20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.93799403 |
| 21 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85038929 |
| 22 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.81672574 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.79436004 |
| 24 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.71628359 |
| 25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.65537580 |
| 26 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.63682072 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.62764737 |
| 28 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.62391250 |
| 29 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.61762412 |
| 30 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.61141198 |
| 31 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.61141198 |
| 32 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.56912023 |
| 33 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.55256503 |
| 34 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.53179544 |
| 35 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.52034843 |
| 36 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.51934463 |
| 37 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.51648446 |
| 38 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.51594880 |
| 39 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.51407340 |
| 40 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.51407340 |
| 41 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.51127291 |
| 42 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.49435394 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.45268394 |
| 44 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.42543532 |
| 45 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.41198506 |
| 46 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.39034976 |
| 47 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.35134941 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34731698 |
| 49 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.34726355 |
| 50 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.34204490 |
| 51 | STAT3_23295773_ChIP-Seq_U87_Human | 1.34195377 |
| 52 | AR_25329375_ChIP-Seq_VCAP_Human | 1.30106914 |
| 53 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.28789020 |
| 54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.28179008 |
| 55 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.26902592 |
| 56 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.26902592 |
| 57 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.25144980 |
| 58 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.24203795 |
| 59 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.23866788 |
| 60 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.22667025 |
| 61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.22016276 |
| 62 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.21603402 |
| 63 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.21317039 |
| 64 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.19797806 |
| 65 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.17818553 |
| 66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.17569749 |
| 67 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.15732334 |
| 68 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.14690361 |
| 69 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.14494167 |
| 70 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12907734 |
| 71 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.12422828 |
| 72 | TCF4_23295773_ChIP-Seq_U87_Human | 1.11611041 |
| 73 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.11266308 |
| 74 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.10448460 |
| 75 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.10035026 |
| 76 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.09527501 |
| 77 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.09455399 |
| 78 | TP53_16413492_ChIP-PET_HCT116_Human | 1.08934627 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 1.08846443 |
| 80 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.08381759 |
| 81 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.07688259 |
| 82 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.06857181 |
| 83 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.06120733 |
| 84 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.05752817 |
| 85 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.04745288 |
| 86 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.03944261 |
| 87 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03680080 |
| 88 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01208903 |
| 89 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.01162374 |
| 90 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.00193474 |
| 91 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.00098563 |
| 92 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.98257200 |
| 93 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.97629492 |
| 94 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.97372695 |
| 95 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.96595129 |
| 96 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.95386926 |
| 97 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.94728584 |
| 98 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.94713294 |
| 99 | JUN_21703547_ChIP-Seq_K562_Human | 0.93771229 |
| 100 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.93425806 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002254_reproductive_system_inflammat | 4.94216367 |
| 2 | MP0003880_abnormal_central_pattern | 4.41442614 |
| 3 | MP0005423_abnormal_somatic_nervous | 3.48201029 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.69220741 |
| 5 | MP0001986_abnormal_taste_sensitivity | 2.61691457 |
| 6 | MP0000372_irregular_coat_pigmentation | 2.46522056 |
| 7 | MP0006054_spinal_hemorrhage | 2.39757262 |
| 8 | MP0006276_abnormal_autonomic_nervous | 2.37270873 |
| 9 | MP0009384_cardiac_valve_regurgitation | 2.27895996 |
| 10 | MP0002160_abnormal_reproductive_system | 2.18113283 |
| 11 | MP0006035_abnormal_mitochondrial_morpho | 2.16878721 |
| 12 | MP0002736_abnormal_nociception_after | 2.04073768 |
| 13 | MP0004885_abnormal_endolymph | 1.89503476 |
| 14 | MP0008058_abnormal_DNA_repair | 1.88499782 |
| 15 | MP0005174_abnormal_tail_pigmentation | 1.86792415 |
| 16 | MP0010368_abnormal_lymphatic_system | 1.86585203 |
| 17 | MP0003119_abnormal_digestive_system | 1.75865926 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 1.74648241 |
| 19 | MP0001485_abnormal_pinna_reflex | 1.73875794 |
| 20 | MP0008995_early_reproductive_senescence | 1.72032024 |
| 21 | MP0001529_abnormal_vocalization | 1.68790369 |
| 22 | MP0002139_abnormal_hepatobiliary_system | 1.62250100 |
| 23 | MP0004147_increased_porphyrin_level | 1.60474713 |
| 24 | MP0003136_yellow_coat_color | 1.59132492 |
| 25 | MP0003718_maternal_effect | 1.55132124 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.52953811 |
| 27 | MP0005075_abnormal_melanosome_morpholog | 1.49189776 |
| 28 | MP0003567_abnormal_fetal_cardiomyocyte | 1.47368987 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.45995663 |
| 30 | MP0005410_abnormal_fertilization | 1.44442916 |
| 31 | MP0000516_abnormal_urinary_system | 1.37434559 |
| 32 | MP0005367_renal/urinary_system_phenotyp | 1.37434559 |
| 33 | MP0004484_altered_response_of | 1.37043879 |
| 34 | MP0002572_abnormal_emotion/affect_behav | 1.34606342 |
| 35 | MP0001984_abnormal_olfaction | 1.34273913 |
| 36 | MP0008875_abnormal_xenobiotic_pharmacok | 1.30382485 |
| 37 | MP0008775_abnormal_heart_ventricle | 1.29751539 |
| 38 | MP0005330_cardiomyopathy | 1.29629104 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.29118189 |
| 40 | MP0002733_abnormal_thermal_nociception | 1.28043828 |
| 41 | MP0003122_maternal_imprinting | 1.27109671 |
| 42 | MP0000749_muscle_degeneration | 1.24351657 |
| 43 | MP0005389_reproductive_system_phenotype | 1.24002622 |
| 44 | MP0009840_abnormal_foam_cell | 1.21839302 |
| 45 | MP0003186_abnormal_redox_activity | 1.21726759 |
| 46 | MP0002102_abnormal_ear_morphology | 1.21209671 |
| 47 | MP0005409_darkened_coat_color | 1.20508248 |
| 48 | MP0002876_abnormal_thyroid_physiology | 1.18191745 |
| 49 | MP0002272_abnormal_nervous_system | 1.14412861 |
| 50 | MP0005595_abnormal_vascular_smooth | 1.13399579 |
| 51 | MP0002009_preneoplasia | 1.10769260 |
| 52 | MP0004085_abnormal_heartbeat | 1.10549749 |
| 53 | MP0004215_abnormal_myocardial_fiber | 1.09767171 |
| 54 | MP0000462_abnormal_digestive_system | 1.09106113 |
| 55 | MP0005647_abnormal_sex_gland | 1.07678064 |
| 56 | MP0001929_abnormal_gametogenesis | 1.07536567 |
| 57 | MP0001756_abnormal_urination | 1.05921447 |
| 58 | MP0000537_abnormal_urethra_morphology | 1.05444977 |
| 59 | MP0001188_hyperpigmentation | 1.04577869 |
| 60 | MP0005332_abnormal_amino_acid | 1.02953385 |
| 61 | MP0000470_abnormal_stomach_morphology | 1.02236577 |
| 62 | MP0002210_abnormal_sex_determination | 1.00881226 |
| 63 | MP0001970_abnormal_pain_threshold | 1.00119831 |
| 64 | MP0005167_abnormal_blood-brain_barrier | 1.00060670 |
| 65 | MP0005253_abnormal_eye_physiology | 0.99506660 |
| 66 | MP0002928_abnormal_bile_duct | 0.98622949 |
| 67 | MP0004133_heterotaxia | 0.98373793 |
| 68 | MP0001324_abnormal_eye_pigmentation | 0.96944521 |
| 69 | MP0003698_abnormal_male_reproductive | 0.94963239 |
| 70 | MP0002163_abnormal_gland_morphology | 0.94825282 |
| 71 | MP0005620_abnormal_muscle_contractility | 0.93480236 |
| 72 | MP0000230_abnormal_systemic_arterial | 0.93435029 |
| 73 | MP0002127_abnormal_cardiovascular_syste | 0.92026723 |
| 74 | MP0001664_abnormal_digestion | 0.91766152 |
| 75 | MP0010094_abnormal_chromosome_stability | 0.91373490 |
| 76 | MP0003137_abnormal_impulse_conducting | 0.90961550 |
| 77 | MP0000427_abnormal_hair_cycle | 0.90022339 |
| 78 | MP0003937_abnormal_limbs/digits/tail_de | 0.89304728 |
| 79 | MP0001486_abnormal_startle_reflex | 0.87712798 |
| 80 | MP0000653_abnormal_sex_gland | 0.87401776 |
| 81 | MP0002229_neurodegeneration | 0.87337293 |
| 82 | MP0004924_abnormal_behavior | 0.87203897 |
| 83 | MP0005386_behavior/neurological_phenoty | 0.87203897 |
| 84 | MP0003195_calcinosis | 0.85291184 |
| 85 | MP0003191_abnormal_cellular_cholesterol | 0.84235791 |
| 86 | MP0003011_delayed_dark_adaptation | 0.83736657 |
| 87 | MP0005365_abnormal_bile_salt | 0.83629956 |
| 88 | MP0001501_abnormal_sleep_pattern | 0.81909068 |
| 89 | MP0008872_abnormal_physiological_respon | 0.79921450 |
| 90 | MP0000015_abnormal_ear_pigmentation | 0.79831290 |
| 91 | MP0001145_abnormal_male_reproductive | 0.79360115 |
| 92 | MP0005645_abnormal_hypothalamus_physiol | 0.79062771 |
| 93 | MP0005448_abnormal_energy_balance | 0.78056819 |
| 94 | MP0005379_endocrine/exocrine_gland_phen | 0.77144155 |
| 95 | MP0000639_abnormal_adrenal_gland | 0.77115411 |
| 96 | MP0000358_abnormal_cell_content/ | 0.77067174 |
| 97 | MP0009745_abnormal_behavioral_response | 0.76829021 |
| 98 | MP0004272_abnormal_basement_membrane | 0.74075621 |
| 99 | MP0002269_muscular_atrophy | 0.73536848 |
| 100 | MP0001879_abnormal_lymphatic_vessel | 0.71420783 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of alanine metabolism (HP:0010916) | 4.41744292 |
| 2 | Hyperalaninemia (HP:0003348) | 4.41744292 |
| 3 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.41744292 |
| 4 | Posterior subcapsular cataract (HP:0007787) | 4.25225492 |
| 5 | Concave nail (HP:0001598) | 4.15970949 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.61028813 |
| 7 | Ependymoma (HP:0002888) | 3.53709944 |
| 8 | Colon cancer (HP:0003003) | 3.26499713 |
| 9 | Hepatic necrosis (HP:0002605) | 3.24275866 |
| 10 | Type I diabetes mellitus (HP:0100651) | 3.19423657 |
| 11 | Hypoplasia of the uterus (HP:0000013) | 2.95610290 |
| 12 | Methylmalonic acidemia (HP:0002912) | 2.94302977 |
| 13 | Increased CSF lactate (HP:0002490) | 2.93612948 |
| 14 | Increased corneal curvature (HP:0100692) | 2.92167157 |
| 15 | Keratoconus (HP:0000563) | 2.92167157 |
| 16 | Congenital, generalized hypertrichosis (HP:0004540) | 2.88374331 |
| 17 | Agnosia (HP:0010524) | 2.88000904 |
| 18 | Methylmalonic aciduria (HP:0012120) | 2.83405455 |
| 19 | Increased serum pyruvate (HP:0003542) | 2.78351306 |
| 20 | Cone-rod dystrophy (HP:0000548) | 2.74846060 |
| 21 | Mitochondrial inheritance (HP:0001427) | 2.72940397 |
| 22 | Abnormality of the labia minora (HP:0012880) | 2.71248440 |
| 23 | Chronic hepatic failure (HP:0100626) | 2.69533945 |
| 24 | Scotoma (HP:0000575) | 2.69408292 |
| 25 | Occipital encephalocele (HP:0002085) | 2.69196890 |
| 26 | Birth length less than 3rd percentile (HP:0003561) | 2.64805638 |
| 27 | Abnormality of glycolysis (HP:0004366) | 2.64339406 |
| 28 | Hypothermia (HP:0002045) | 2.53093848 |
| 29 | Abnormality of serum amino acid levels (HP:0003112) | 2.52813867 |
| 30 | Increased serum lactate (HP:0002151) | 2.52145172 |
| 31 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.50093201 |
| 32 | Limb dystonia (HP:0002451) | 2.48429050 |
| 33 | CNS demyelination (HP:0007305) | 2.48049426 |
| 34 | Abnormality of macular pigmentation (HP:0008002) | 2.46366199 |
| 35 | Constricted visual fields (HP:0001133) | 2.44457759 |
| 36 | Retinal atrophy (HP:0001105) | 2.42859027 |
| 37 | True hermaphroditism (HP:0010459) | 2.42270916 |
| 38 | Subcapsular cataract (HP:0000523) | 2.39426108 |
| 39 | Prostate neoplasm (HP:0100787) | 2.38378133 |
| 40 | Macular degeneration (HP:0000608) | 2.32796164 |
| 41 | Generalized aminoaciduria (HP:0002909) | 2.29019642 |
| 42 | Nephronophthisis (HP:0000090) | 2.28378145 |
| 43 | Anencephaly (HP:0002323) | 2.27683068 |
| 44 | Dysdiadochokinesis (HP:0002075) | 2.27176645 |
| 45 | Lactic acidosis (HP:0003128) | 2.25828695 |
| 46 | Abnormality of midbrain morphology (HP:0002418) | 2.23124584 |
| 47 | Molar tooth sign on MRI (HP:0002419) | 2.23124584 |
| 48 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.22598168 |
| 49 | Homocystinuria (HP:0002156) | 2.22172635 |
| 50 | Abnormality of homocysteine metabolism (HP:0010919) | 2.22172635 |
| 51 | Short tibia (HP:0005736) | 2.21599729 |
| 52 | Polyphagia (HP:0002591) | 2.18363453 |
| 53 | Pancreatic cysts (HP:0001737) | 2.17991845 |
| 54 | Focal segmental glomerulosclerosis (HP:0000097) | 2.17605029 |
| 55 | Hyperglycinemia (HP:0002154) | 2.15647955 |
| 56 | Astrocytoma (HP:0009592) | 2.15426222 |
| 57 | Abnormality of the astrocytes (HP:0100707) | 2.15426222 |
| 58 | Abnormal hair whorl (HP:0010721) | 2.14971010 |
| 59 | Respiratory difficulties (HP:0002880) | 2.11829224 |
| 60 | Glioma (HP:0009733) | 2.11429392 |
| 61 | Hyperglycemia (HP:0003074) | 2.09871085 |
| 62 | Pancreatic fibrosis (HP:0100732) | 2.06880984 |
| 63 | Septate vagina (HP:0001153) | 2.06038276 |
| 64 | Glomerulosclerosis (HP:0000096) | 2.04322010 |
| 65 | Abnormality of the renal medulla (HP:0100957) | 2.03949116 |
| 66 | Genetic anticipation (HP:0003743) | 2.01414022 |
| 67 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.00215564 |
| 68 | CNS hypomyelination (HP:0003429) | 1.99448591 |
| 69 | Ulnar claw (HP:0001178) | 1.98402554 |
| 70 | Facial diplegia (HP:0001349) | 1.98255069 |
| 71 | Acute necrotizing encephalopathy (HP:0006965) | 1.97923050 |
| 72 | Anterior segment dysgenesis (HP:0007700) | 1.95939158 |
| 73 | Acute encephalopathy (HP:0006846) | 1.94407529 |
| 74 | Emotional lability (HP:0000712) | 1.94363254 |
| 75 | Central scotoma (HP:0000603) | 1.90326429 |
| 76 | Attenuation of retinal blood vessels (HP:0007843) | 1.89220913 |
| 77 | Proximal tubulopathy (HP:0000114) | 1.86928421 |
| 78 | Abnormality of the ischium (HP:0003174) | 1.86588068 |
| 79 | Nasal speech (HP:0001611) | 1.86364228 |
| 80 | Thyroid-stimulating hormone excess (HP:0002925) | 1.86153631 |
| 81 | Progressive cerebellar ataxia (HP:0002073) | 1.85104889 |
| 82 | Limb hypertonia (HP:0002509) | 1.85036179 |
| 83 | Tubulointerstitial nephritis (HP:0001970) | 1.82022861 |
| 84 | Congenital stationary night blindness (HP:0007642) | 1.81624765 |
| 85 | Glycosuria (HP:0003076) | 1.81372011 |
| 86 | Abnormality of urine glucose concentration (HP:0011016) | 1.81372011 |
| 87 | Hemiparesis (HP:0001269) | 1.80623397 |
| 88 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.79956855 |
| 89 | Abolished electroretinogram (ERG) (HP:0000550) | 1.79541658 |
| 90 | Bile duct proliferation (HP:0001408) | 1.78320255 |
| 91 | Abnormal biliary tract physiology (HP:0012439) | 1.78320255 |
| 92 | Hypoalphalipoproteinemia (HP:0003233) | 1.78231360 |
| 93 | Abnormality of vitamin B metabolism (HP:0004340) | 1.77712643 |
| 94 | Chorioretinal atrophy (HP:0000533) | 1.77044147 |
| 95 | Poor suck (HP:0002033) | 1.75724040 |
| 96 | Amelogenesis imperfecta (HP:0000705) | 1.74676928 |
| 97 | Respiratory failure (HP:0002878) | 1.74254678 |
| 98 | Spontaneous abortion (HP:0005268) | 1.74220204 |
| 99 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.72467398 |
| 100 | Cerebral edema (HP:0002181) | 1.72113771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PDK2 | 4.54187486 |
| 2 | MST4 | 4.49400355 |
| 3 | TAF1 | 4.32681417 |
| 4 | PNCK | 3.57669833 |
| 5 | MAP4K2 | 3.35797391 |
| 6 | TRIM28 | 3.14152082 |
| 7 | VRK2 | 3.10083104 |
| 8 | TAOK3 | 2.52932715 |
| 9 | BCKDK | 2.52002050 |
| 10 | CDK19 | 2.31209014 |
| 11 | WEE1 | 2.27911219 |
| 12 | ZAK | 2.04631041 |
| 13 | GRK1 | 1.96130192 |
| 14 | SIK3 | 1.94420553 |
| 15 | WNK4 | 1.91320385 |
| 16 | KIT | 1.83543971 |
| 17 | ADRBK2 | 1.81313148 |
| 18 | NUAK1 | 1.77119888 |
| 19 | MAP3K10 | 1.69302020 |
| 20 | STK39 | 1.64840699 |
| 21 | ACVR1B | 1.50939980 |
| 22 | BCR | 1.42763473 |
| 23 | VRK1 | 1.41410837 |
| 24 | WNK3 | 1.38697300 |
| 25 | TNIK | 1.37320104 |
| 26 | DYRK1B | 1.28761708 |
| 27 | FRK | 1.24255973 |
| 28 | CAMKK2 | 1.21360948 |
| 29 | PINK1 | 1.18277313 |
| 30 | PBK | 1.16860987 |
| 31 | TSSK6 | 1.07484728 |
| 32 | PASK | 1.07019774 |
| 33 | PAK3 | 1.05561489 |
| 34 | DAPK2 | 1.01920542 |
| 35 | FES | 0.97743262 |
| 36 | MAPK15 | 0.95867572 |
| 37 | STK38 | 0.92699887 |
| 38 | MINK1 | 0.88074849 |
| 39 | PTK2B | 0.86998393 |
| 40 | DAPK1 | 0.86487606 |
| 41 | INSRR | 0.85839870 |
| 42 | PLK3 | 0.83305375 |
| 43 | CDK3 | 0.80279124 |
| 44 | TGFBR1 | 0.79758633 |
| 45 | STK16 | 0.78309519 |
| 46 | MATK | 0.78108691 |
| 47 | BMPR1B | 0.78101966 |
| 48 | CAMK2D | 0.74857934 |
| 49 | OXSR1 | 0.72137376 |
| 50 | MET | 0.69953539 |
| 51 | PRKCG | 0.67826970 |
| 52 | GRK5 | 0.64853579 |
| 53 | RPS6KB1 | 0.62711322 |
| 54 | DYRK2 | 0.62376591 |
| 55 | MAP3K12 | 0.61939155 |
| 56 | NLK | 0.61575674 |
| 57 | NEK9 | 0.59414870 |
| 58 | BRSK2 | 0.58466858 |
| 59 | CAMK2A | 0.57090087 |
| 60 | PRKCE | 0.57060532 |
| 61 | DAPK3 | 0.56125837 |
| 62 | MAP2K6 | 0.55918287 |
| 63 | PHKG2 | 0.54811578 |
| 64 | PHKG1 | 0.54811578 |
| 65 | PLK4 | 0.54106556 |
| 66 | TESK1 | 0.52039039 |
| 67 | CCNB1 | 0.51288966 |
| 68 | NTRK2 | 0.51096713 |
| 69 | PRKG1 | 0.49090305 |
| 70 | PLK2 | 0.45158626 |
| 71 | MAPK13 | 0.44987610 |
| 72 | RIPK4 | 0.41929495 |
| 73 | ATR | 0.41564456 |
| 74 | MAP3K2 | 0.40936637 |
| 75 | NEK1 | 0.40036442 |
| 76 | GSK3A | 0.39328170 |
| 77 | MELK | 0.37447141 |
| 78 | YES1 | 0.36164875 |
| 79 | ADRBK1 | 0.35990042 |
| 80 | PDGFRB | 0.34829596 |
| 81 | MYLK | 0.34354029 |
| 82 | CSF1R | 0.33746056 |
| 83 | OBSCN | 0.33501203 |
| 84 | PLK1 | 0.33352005 |
| 85 | EIF2AK3 | 0.32975297 |
| 86 | MAP3K5 | 0.32121293 |
| 87 | CDK7 | 0.29614565 |
| 88 | EPHB2 | 0.29574392 |
| 89 | FLT3 | 0.29507571 |
| 90 | PRKACA | 0.29025823 |
| 91 | ATM | 0.28442694 |
| 92 | ERBB4 | 0.26847425 |
| 93 | PRKCB | 0.26248955 |
| 94 | ABL2 | 0.26231793 |
| 95 | CSNK1D | 0.25999153 |
| 96 | CSNK1A1 | 0.25808634 |
| 97 | CSNK2A1 | 0.25188537 |
| 98 | CSNK1E | 0.24925053 |
| 99 | MAPK9 | 0.24365366 |
| 100 | PRKCA | 0.24353498 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Selenocompound metabolism_Homo sapiens_hsa00450 | 3.31785852 |
| 2 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 3.11936302 |
| 3 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.97093185 |
| 4 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.65494676 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.60500861 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.20507846 |
| 7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.18382321 |
| 8 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.16669991 |
| 9 | ABC transporters_Homo sapiens_hsa02010 | 2.12905671 |
| 10 | Phototransduction_Homo sapiens_hsa04744 | 2.11251429 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.09298298 |
| 12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.98344596 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.91943674 |
| 14 | Olfactory transduction_Homo sapiens_hsa04740 | 1.85266416 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.83570666 |
| 16 | Mismatch repair_Homo sapiens_hsa03430 | 1.83345054 |
| 17 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.75344207 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.74697667 |
| 19 | Parkinsons disease_Homo sapiens_hsa05012 | 1.69659769 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.67520439 |
| 21 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.59910715 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.59447513 |
| 23 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.56067991 |
| 24 | Circadian entrainment_Homo sapiens_hsa04713 | 1.44508398 |
| 25 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.34764742 |
| 26 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.31468588 |
| 27 | Homologous recombination_Homo sapiens_hsa03440 | 1.30828047 |
| 28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.27462875 |
| 29 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.27440513 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.26806698 |
| 31 | Histidine metabolism_Homo sapiens_hsa00340 | 1.23993724 |
| 32 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.23688755 |
| 33 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.22282451 |
| 34 | RNA degradation_Homo sapiens_hsa03018 | 1.22169500 |
| 35 | Taste transduction_Homo sapiens_hsa04742 | 1.20165745 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.19572944 |
| 37 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.18007347 |
| 38 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15461349 |
| 39 | RNA polymerase_Homo sapiens_hsa03020 | 1.12037225 |
| 40 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.11846287 |
| 41 | Insulin secretion_Homo sapiens_hsa04911 | 1.06428971 |
| 42 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.05918966 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.05838938 |
| 44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.03058214 |
| 45 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.01235277 |
| 46 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.00237635 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.98099334 |
| 48 | DNA replication_Homo sapiens_hsa03030 | 0.97225526 |
| 49 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.97109133 |
| 50 | Proteasome_Homo sapiens_hsa03050 | 0.92691636 |
| 51 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.91828894 |
| 52 | Huntingtons disease_Homo sapiens_hsa05016 | 0.91768786 |
| 53 | Ribosome_Homo sapiens_hsa03010 | 0.91178334 |
| 54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.90462587 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90245974 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.89265542 |
| 57 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.88636528 |
| 58 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.84608286 |
| 59 | Salivary secretion_Homo sapiens_hsa04970 | 0.84579909 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.81458902 |
| 61 | Alzheimers disease_Homo sapiens_hsa05010 | 0.81139432 |
| 62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.80992320 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.80593445 |
| 64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.79419589 |
| 65 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.77818067 |
| 66 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.76085097 |
| 67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.74407890 |
| 68 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.71647923 |
| 69 | Morphine addiction_Homo sapiens_hsa05032 | 0.70774585 |
| 70 | Base excision repair_Homo sapiens_hsa03410 | 0.69260815 |
| 71 | Mineral absorption_Homo sapiens_hsa04978 | 0.66695406 |
| 72 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66213715 |
| 73 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.65533951 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65193888 |
| 75 | Sulfur relay system_Homo sapiens_hsa04122 | 0.64852254 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.64539128 |
| 77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.61858517 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.60578402 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60300406 |
| 80 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.59853886 |
| 81 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.58936413 |
| 82 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.57819792 |
| 83 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.57819260 |
| 84 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.57797273 |
| 85 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.56937493 |
| 86 | RNA transport_Homo sapiens_hsa03013 | 0.56892599 |
| 87 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.56736603 |
| 88 | Nicotine addiction_Homo sapiens_hsa05033 | 0.54008421 |
| 89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.51303568 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.49915020 |
| 91 | Galactose metabolism_Homo sapiens_hsa00052 | 0.49878793 |
| 92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.48882023 |
| 93 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.46192503 |
| 94 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.45020045 |
| 95 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44492765 |
| 96 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.43827572 |
| 97 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.42289984 |
| 98 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.42110984 |
| 99 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.40905376 |
| 100 | Cell cycle_Homo sapiens_hsa04110 | 0.40472298 |

