TRA2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1gonadal mesoderm development (GO:0007506)5.65109320
2mitotic chromosome condensation (GO:0007076)4.67373530
3regulation of centriole replication (GO:0046599)4.47228318
4telomere maintenance via semi-conservative replication (GO:0032201)4.29295637
5nuclear pore complex assembly (GO:0051292)4.25082977
6DNA strand elongation involved in DNA replication (GO:0006271)4.21687290
7kinetochore organization (GO:0051383)4.18696578
8nuclear pore organization (GO:0006999)4.17836903
9telomere maintenance via recombination (GO:0000722)4.15632591
10DNA dealkylation (GO:0035510)4.12219133
11DNA replication initiation (GO:0006270)4.10521010
12DNA unwinding involved in DNA replication (GO:0006268)4.05950576
13mitotic recombination (GO:0006312)4.04046062
14DNA strand elongation (GO:0022616)4.03721713
15regulation of nuclear cell cycle DNA replication (GO:0033262)3.98295175
16DNA replication checkpoint (GO:0000076)3.94729497
17CENP-A containing nucleosome assembly (GO:0034080)3.88181376
18DNA duplex unwinding (GO:0032508)3.86337962
19chromatin remodeling at centromere (GO:0031055)3.85543913
20DNA topological change (GO:0006265)3.84405321
21DNA geometric change (GO:0032392)3.82042901
22regulation of histone H3-K9 methylation (GO:0051570)3.80248702
23DNA replication-independent nucleosome organization (GO:0034724)3.74271413
24DNA replication-independent nucleosome assembly (GO:0006336)3.74271413
25kinetochore assembly (GO:0051382)3.65554855
26negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.64166399
27negative regulation of chromosome segregation (GO:0051985)3.62167850
28negative regulation of mitotic sister chromatid separation (GO:2000816)3.56456356
29negative regulation of sister chromatid segregation (GO:0033046)3.56456356
30negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.56456356
31negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.56456356
32negative regulation of mitotic sister chromatid segregation (GO:0033048)3.56456356
33negative regulation of histone methylation (GO:0031061)3.56178912
34regulation of centrosome cycle (GO:0046605)3.54473504
35ribosome assembly (GO:0042255)3.51664697
36regulation of RNA export from nucleus (GO:0046831)3.50169751
37termination of RNA polymerase II transcription (GO:0006369)3.49768082
38mitotic metaphase plate congression (GO:0007080)3.48480735
39negative regulation of mRNA processing (GO:0050686)3.46975283
40DNA ligation (GO:0006266)3.46523225
41regulation of centrosome duplication (GO:0010824)3.45362689
42regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.44966883
43IMP biosynthetic process (GO:0006188)3.44960785
44negative regulation of RNA splicing (GO:0033119)3.42760339
45telomere maintenance via telomere lengthening (GO:0010833)3.41823569
46negative regulation of DNA repair (GO:0045738)3.39746544
47protein localization to kinetochore (GO:0034501)3.38967730
48regulation of mitotic metaphase/anaphase transition (GO:0030071)3.38329270
49regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.38329270
50regulation of helicase activity (GO:0051095)3.38177647
51regulation of DNA endoreduplication (GO:0032875)3.38102703
52regulation of mitotic sister chromatid separation (GO:0010965)3.37550057
53regulation of mitotic sister chromatid segregation (GO:0033047)3.37550057
54regulation of sister chromatid segregation (GO:0033045)3.37550057
55glomerulus development (GO:0032835)3.37357492
56regulation of mitotic spindle checkpoint (GO:1903504)3.36395167
57regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.36395167
58nucleobase biosynthetic process (GO:0046112)3.36256128
59nucleotide-excision repair, DNA gap filling (GO:0006297)3.35856736
60heterochromatin organization (GO:0070828)3.32750587
61maturation of 5.8S rRNA (GO:0000460)3.32147201
62mitotic spindle assembly checkpoint (GO:0007094)3.32034051
63spindle checkpoint (GO:0031577)3.31182721
64mitotic spindle checkpoint (GO:0071174)3.30111604
65mitotic nuclear envelope disassembly (GO:0007077)3.29730392
66intra-S DNA damage checkpoint (GO:0031573)3.28064441
67mRNA export from nucleus (GO:0006406)3.28006444
68spindle assembly checkpoint (GO:0071173)3.27769744
69mitotic sister chromatid cohesion (GO:0007064)3.24965385
70pore complex assembly (GO:0046931)3.24601053
71establishment of integrated proviral latency (GO:0075713)3.24503813
72metaphase plate congression (GO:0051310)3.24422451
73regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.23636010
74mRNA splice site selection (GO:0006376)3.23525920
75regulation of chromosome segregation (GO:0051983)3.22436010
76regulation of spindle organization (GO:0090224)3.20887721
77RNA export from nucleus (GO:0006405)3.20709807
78non-recombinational repair (GO:0000726)3.20002337
79double-strand break repair via nonhomologous end joining (GO:0006303)3.20002337
80regulation of DNA damage checkpoint (GO:2000001)3.16503229
81DNA double-strand break processing (GO:0000729)3.14362683
82mitotic G2/M transition checkpoint (GO:0044818)3.14299426
83telomere maintenance (GO:0000723)3.13452003
84monoubiquitinated protein deubiquitination (GO:0035520)3.13220768
85chromosome condensation (GO:0030261)3.11596498
86negative regulation of cell cycle G2/M phase transition (GO:1902750)3.10357809
87histone exchange (GO:0043486)3.09470378
88telomere organization (GO:0032200)3.09129853
89DNA conformation change (GO:0071103)3.05789900
90V(D)J recombination (GO:0033151)3.05553486
91regulation of double-strand break repair via homologous recombination (GO:0010569)3.02567730
92nuclear envelope disassembly (GO:0051081)3.01899716
93membrane disassembly (GO:0030397)3.01899716
94rRNA modification (GO:0000154)3.01439493
95regulation of mitotic spindle organization (GO:0060236)3.01111590
96glucocorticoid receptor signaling pathway (GO:0042921)3.00964195
97trophoblast giant cell differentiation (GO:0060707)2.99163680
98replication fork processing (GO:0031297)2.99112397
99purine nucleobase biosynthetic process (GO:0009113)2.97932393
100rRNA methylation (GO:0031167)2.97388480
101ribosomal small subunit assembly (GO:0000028)2.97374489
102meiotic chromosome segregation (GO:0045132)2.95974536
103protein K6-linked ubiquitination (GO:0085020)2.95842903
104cell differentiation involved in metanephros development (GO:0072202)2.95649419
105viral mRNA export from host cell nucleus (GO:0046784)2.93425836
106DNA replication-dependent nucleosome assembly (GO:0006335)2.93270258
107DNA replication-dependent nucleosome organization (GO:0034723)2.93270258
108translesion synthesis (GO:0019985)2.93171043
109transcription-coupled nucleotide-excision repair (GO:0006283)2.92980562
110* RNA splicing, via transesterification reactions (GO:0000375)2.91716653
111protein localization to chromosome (GO:0034502)2.91419823
112maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.91270070
113DNA synthesis involved in DNA repair (GO:0000731)2.90898029
114DNA-templated transcription, termination (GO:0006353)2.89702656
115* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.89134068
116* mRNA splicing, via spliceosome (GO:0000398)2.89134068
117DNA strand renaturation (GO:0000733)2.87651228
118positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.86027860
119positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.86027860
120positive regulation of mitotic sister chromatid separation (GO:1901970)2.86027860
121mRNA transport (GO:0051028)2.81205272
122positive regulation of chromosome segregation (GO:0051984)2.80188083
123establishment of chromosome localization (GO:0051303)2.79956434
124protein localization to chromosome, centromeric region (GO:0071459)2.79253945
125attachment of spindle microtubules to kinetochore (GO:0008608)2.77589613
126mismatch repair (GO:0006298)2.77511547
127N-terminal protein amino acid acetylation (GO:0006474)2.77492857
128IMP metabolic process (GO:0046040)2.76936923
129positive regulation of male gonad development (GO:2000020)2.76852825
130dosage compensation (GO:0007549)2.76480869
131alternative mRNA splicing, via spliceosome (GO:0000380)2.76115938
132somatic diversification of immune receptors via somatic mutation (GO:0002566)2.73375610
133somatic hypermutation of immunoglobulin genes (GO:0016446)2.73375610
134RNA-dependent DNA replication (GO:0006278)2.72463687
135negative regulation of mRNA metabolic process (GO:1903312)2.72039096
136ATP-dependent chromatin remodeling (GO:0043044)2.71258078
137negative regulation of phagocytosis (GO:0050765)2.70822597
138ribosome biogenesis (GO:0042254)2.69775751
139chromatin assembly or disassembly (GO:0006333)2.67853745
140mitotic sister chromatid segregation (GO:0000070)2.67347769
141negative regulation of DNA-dependent DNA replication (GO:2000104)2.66968021
142sister chromatid segregation (GO:0000819)2.66499644
143DNA deamination (GO:0045006)2.65802459
144chromosome segregation (GO:0007059)2.64508477

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F4_17652178_ChIP-ChIP_JURKAT_Human4.51776270
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.94279315
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.94028252
4TP63_19390658_ChIP-ChIP_HaCaT_Human3.37321200
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.36653005
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.82135099
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.76074806
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.59381479
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.54882279
10NELFA_20434984_ChIP-Seq_ESCs_Mouse2.50693899
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.46564279
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.45781737
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.44453490
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.40211680
15AR_21909140_ChIP-Seq_LNCAP_Human2.39448821
16E2F1_21310950_ChIP-Seq_MCF-7_Human2.29725001
17* CIITA_25753668_ChIP-Seq_RAJI_Human2.28381809
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.27630482
19NOTCH1_21737748_ChIP-Seq_TLL_Human2.21515892
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.21123353
21ELK1_19687146_ChIP-ChIP_HELA_Human2.15654609
22GABP_17652178_ChIP-ChIP_JURKAT_Human2.13684726
23MYC_18358816_ChIP-ChIP_MESCs_Mouse2.13361618
24VDR_23849224_ChIP-Seq_CD4+_Human2.11385357
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.10376324
26ELF1_17652178_ChIP-ChIP_JURKAT_Human2.08803441
27E2F7_22180533_ChIP-Seq_HELA_Human11.0599620
28CREB1_15753290_ChIP-ChIP_HEK293T_Human1.94125790
29* TTF2_22483619_ChIP-Seq_HELA_Human1.91313717
30* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.90441821
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.86226455
32FOXP3_21729870_ChIP-Seq_TREG_Human1.84186646
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.83898362
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.80097424
35XRN2_22483619_ChIP-Seq_HELA_Human1.77342940
36* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.74651605
37JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70857648
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.63338545
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63276849
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.59157796
41FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.55526295
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.55486648
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.54011652
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51243179
45* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.49200341
46MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.46422503
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.44455278
48IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.44358506
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.43220542
50NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41734998
51DCP1A_22483619_ChIP-Seq_HELA_Human1.37767032
52POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.34793142
53* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.33420562
54SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.32167851
55ZFX_18555785_ChIP-Seq_MESCs_Mouse1.31996249
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31986033
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27707369
58SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.27031120
59CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.26914168
60SCL_19346495_ChIP-Seq_HPC-7_Human1.25603701
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.25507214
62SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25430173
63MYC_22102868_ChIP-Seq_BL_Human1.24749395
64FUS_26573619_Chip-Seq_HEK293_Human1.23763090
65PKCTHETA_26484144_Chip-Seq_BREAST_Human1.23677828
66IRF1_19129219_ChIP-ChIP_H3396_Human1.18712160
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.18174072
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.16741528
69GABP_19822575_ChIP-Seq_HepG2_Human1.16280764
70SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14458631
71ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14241726
72PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.13766578
73GATA1_22025678_ChIP-Seq_K562_Human1.11520435
74RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10751273
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09494693
76SRF_21415370_ChIP-Seq_HL-1_Mouse1.06150630
77CHD1_26751641_Chip-Seq_LNCaP_Human1.05542958
78MYC_18940864_ChIP-ChIP_HL60_Human1.05114777
79* EWS_26573619_Chip-Seq_HEK293_Human1.04522174
80FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03207865
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.01499590
82BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98430990
83E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.97589480
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.96413653
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95694759
86TFEB_21752829_ChIP-Seq_HELA_Human0.93715290
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93082453
88SPI1_23547873_ChIP-Seq_NB4_Human0.92771999
89DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.92513788
90* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89352599
91STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.89067450
92YY1_21170310_ChIP-Seq_MESCs_Mouse0.87145405
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87017714
94THAP11_20581084_ChIP-Seq_MESCs_Mouse0.86611414
95KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.84886617
96KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.84886617
97KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.84886617
98SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.84643868
99NANOG_16153702_ChIP-ChIP_HESCs_Human0.83886833
100* KDM5A_27292631_Chip-Seq_BREAST_Human0.83022994
101FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.82303186
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.81871117
103* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.81036164
104FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.79022219
105NANOG_21062744_ChIP-ChIP_HESCs_Human0.78655801
106* MYB_26560356_Chip-Seq_TH2_Human0.78450460
107VDR_22108803_ChIP-Seq_LS180_Human0.78044225
108* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.75570314
109SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.74902677
110STAT4_19710469_ChIP-ChIP_TH1__Mouse0.74470471
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.72153161
112SOX2_16153702_ChIP-ChIP_HESCs_Human0.71711132
113FLI1_27457419_Chip-Seq_LIVER_Mouse0.70655272
114MYB_26560356_Chip-Seq_TH1_Human0.69960823
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.69344566

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.01387026
2MP0010094_abnormal_chromosome_stability3.81418904
3MP0003111_abnormal_nucleus_morphology3.50532915
4MP0003693_abnormal_embryo_hatching3.47433827
5MP0003941_abnormal_skin_development3.09155283
6MP0008007_abnormal_cellular_replicative3.06001781
7MP0003077_abnormal_cell_cycle2.80820552
8MP0004957_abnormal_blastocyst_morpholog2.78678913
9MP0008058_abnormal_DNA_repair2.36205874
10MP0006292_abnormal_olfactory_placode2.32407380
11MP0009379_abnormal_foot_pigmentation2.27040614
12MP0002396_abnormal_hematopoietic_system2.18419098
13MP0008932_abnormal_embryonic_tissue2.04335500
14MP0003786_premature_aging1.97864119
15MP0008438_abnormal_cutaneous_collagen1.83328646
16MP0008877_abnormal_DNA_methylation1.82536852
17MP0005503_abnormal_tendon_morphology1.82372452
18MP0003890_abnormal_embryonic-extraembry1.79126030
19MP0003123_paternal_imprinting1.76347495
20MP0010352_gastrointestinal_tract_polyps1.73220097
21MP0003121_genomic_imprinting1.70721872
22MP0005275_abnormal_skin_tensile1.69380452
23MP0000350_abnormal_cell_proliferation1.64458153
24MP0009697_abnormal_copulation1.64003059
25MP0003115_abnormal_respiratory_system1.62951986
26MP0003787_abnormal_imprinting1.57653622
27MP0009053_abnormal_anal_canal1.52002467
28MP0009672_abnormal_birth_weight1.50130415
29MP0004808_abnormal_hematopoietic_stem1.43866546
30MP0003718_maternal_effect1.40122174
31MP0003763_abnormal_thymus_physiology1.39611082
32MP0000537_abnormal_urethra_morphology1.38914878
33MP0005380_embryogenesis_phenotype1.35483788
34MP0001672_abnormal_embryogenesis/_devel1.35483788
35MP0000490_abnormal_crypts_of1.35409481
36MP0001730_embryonic_growth_arrest1.29162643
37MP0002160_abnormal_reproductive_system1.26928793
38MP0002697_abnormal_eye_size1.26702143
39MP0005409_darkened_coat_color1.26370755
40MP0010307_abnormal_tumor_latency1.22004632
41MP0002210_abnormal_sex_determination1.21093102
42MP0001119_abnormal_female_reproductive1.20684654
43MP0009703_decreased_birth_body1.20343457
44MP0005389_reproductive_system_phenotype1.20281537
45MP0003984_embryonic_growth_retardation1.17280451
46MP0001879_abnormal_lymphatic_vessel1.16001340
47MP0001697_abnormal_embryo_size1.15480479
48MP0002009_preneoplasia1.15281631
49MP0002282_abnormal_trachea_morphology1.15117986
50MP0008995_early_reproductive_senescence1.13620480
51MP0000313_abnormal_cell_death1.13120074
52MP0001919_abnormal_reproductive_system1.12990599
53MP0001293_anophthalmia1.12820372
54MP0000703_abnormal_thymus_morphology1.11988416
55MP0006054_spinal_hemorrhage1.10315556
56MP0000465_gastrointestinal_hemorrhage1.10155264
57MP0003385_abnormal_body_wall1.08879707
58MP0000566_synostosis1.08332021
59MP0009333_abnormal_splenocyte_physiolog1.07926253
60MP0002085_abnormal_embryonic_tissue1.07512455
61MP0002132_abnormal_respiratory_system1.07139621
62MP0003567_abnormal_fetal_cardiomyocyte1.07061990
63MP0008961_abnormal_basal_metabolism1.06175492
64MP0002088_abnormal_embryonic_growth/wei1.05443697
65MP0002398_abnormal_bone_marrow1.05388855
66MP0001188_hyperpigmentation1.04913867
67* MP0002086_abnormal_extraembryonic_tissu0.99915314
68MP0002019_abnormal_tumor_incidence0.99731261
69* MP0002080_prenatal_lethality0.99059945
70MP0004197_abnormal_fetal_growth/weight/0.98384210
71MP0006035_abnormal_mitochondrial_morpho0.98268317
72MP0004185_abnormal_adipocyte_glucose0.96854791
73MP0002111_abnormal_tail_morphology0.96796806
74MP0003315_abnormal_perineum_morphology0.96297243
75MP0005076_abnormal_cell_differentiation0.96259563
76MP0000428_abnormal_craniofacial_morphol0.95758013
77MP0002166_altered_tumor_susceptibility0.94753591
78MP0002084_abnormal_developmental_patter0.93244899
79MP0001145_abnormal_male_reproductive0.91001769
80MP0005367_renal/urinary_system_phenotyp0.90832732
81MP0000516_abnormal_urinary_system0.90832732
82MP0001545_abnormal_hematopoietic_system0.90704546
83MP0005397_hematopoietic_system_phenotyp0.90704546
84MP0003221_abnormal_cardiomyocyte_apopto0.90663959
85MP0002095_abnormal_skin_pigmentation0.90476415
86MP0002722_abnormal_immune_system0.90153692
87MP0003942_abnormal_urinary_system0.88534113
88MP0002092_abnormal_eye_morphology0.88354722
89MP0000767_abnormal_smooth_muscle0.87413227
90MP0002006_tumorigenesis0.86271681
91MP0000689_abnormal_spleen_morphology0.85323724
92MP0010030_abnormal_orbit_morphology0.84800647
93MP0000653_abnormal_sex_gland0.84385966
94MP0003937_abnormal_limbs/digits/tail_de0.83894016
95MP0003755_abnormal_palate_morphology0.83768623
96MP0001915_intracranial_hemorrhage0.83703391
97MP0001853_heart_inflammation0.83303437
98MP0002060_abnormal_skin_morphology0.83129562
99MP0003943_abnormal_hepatobiliary_system0.82475170
100MP0002938_white_spotting0.82161874
101MP0000432_abnormal_head_morphology0.81586389
102MP0001286_abnormal_eye_development0.79844083
103MP0001835_abnormal_antigen_presentation0.78450484
104MP0005394_taste/olfaction_phenotype0.77679062
105MP0005499_abnormal_olfactory_system0.77679062
106MP0005187_abnormal_penis_morphology0.77401906
107MP0003828_pulmonary_edema0.77237537
108MP0006072_abnormal_retinal_apoptosis0.77212598
109MP0002429_abnormal_blood_cell0.76977113
110MP0001929_abnormal_gametogenesis0.76670263
111MP0005671_abnormal_response_to0.76225380
112MP0001175_abnormal_lung_morphology0.75925959
113MP0000613_abnormal_salivary_gland0.75867102
114MP0005083_abnormal_biliary_tract0.74638890
115MP0000716_abnormal_immune_system0.73001404
116MP0005621_abnormal_cell_physiology0.71235334
117MP0005508_abnormal_skeleton_morphology0.71030398
118MP0003861_abnormal_nervous_system0.70183008
119MP0001346_abnormal_lacrimal_gland0.68023211
120MP0000049_abnormal_middle_ear0.67150863
121MP0001243_abnormal_dermal_layer0.66835920
122MP0000631_abnormal_neuroendocrine_gland0.66321185
123MP0002148_abnormal_hypersensitivity_rea0.66007968
124MP0002233_abnormal_nose_morphology0.65817415
125MP0001958_emphysema0.65783794
126MP0005384_cellular_phenotype0.63816053
127MP0005220_abnormal_exocrine_pancreas0.61909147
128MP0005391_vision/eye_phenotype0.61337609
129MP0003699_abnormal_female_reproductive0.60131235
130MP0003119_abnormal_digestive_system0.59807627
131MP0002114_abnormal_axial_skeleton0.59244832
132MP0003698_abnormal_male_reproductive0.59023752
133MP0002081_perinatal_lethality0.58505975
134MP0003935_abnormal_craniofacial_develop0.58228292
135MP0001340_abnormal_eyelid_morphology0.57156396
136MP0009278_abnormal_bone_marrow0.55729994

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.28467234
2Birth length less than 3rd percentile (HP:0003561)4.27461179
3Impulsivity (HP:0100710)3.96046549
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.72572227
5Chromsome breakage (HP:0040012)3.64674302
6Short middle phalanx of the 5th finger (HP:0004220)3.56668860
7Abnormality of the nasal septum (HP:0000419)3.27995011
8Abnormality of the columella (HP:0009929)3.18883712
9Aplastic anemia (HP:0001915)3.12503927
10Acute lymphatic leukemia (HP:0006721)3.09418527
11Abnormal hair whorl (HP:0010721)3.05871653
12Shawl scrotum (HP:0000049)3.02736306
13Ectopic kidney (HP:0000086)3.02682709
14Abnormality of the parietal bone (HP:0002696)3.00374580
15Long eyelashes (HP:0000527)2.92300485
16Microvesicular hepatic steatosis (HP:0001414)2.88354131
17Sloping forehead (HP:0000340)2.75702299
18Long foot (HP:0001833)2.69651970
19Abnormality of the pons (HP:0007361)2.69602654
20Abnormality of incisor morphology (HP:0011063)2.68678009
21Reticulocytopenia (HP:0001896)2.64492257
22Abnormality of the incisor (HP:0000676)2.63987591
23Absent forearm bone (HP:0003953)2.57706443
24Overlapping toe (HP:0001845)2.57450411
25Abnormality of chromosome stability (HP:0003220)2.51742216
26Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.51244979
27Abnormality of the labia minora (HP:0012880)2.48985586
28Abnormal lung lobation (HP:0002101)2.46943726
29Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.45232788
30Volvulus (HP:0002580)2.44342827
31Capillary hemangiomas (HP:0005306)2.42677511
32Depressed nasal tip (HP:0000437)2.42319762
33Syringomyelia (HP:0003396)2.42184459
34Spinal cord lesions (HP:0100561)2.42184459
35Abnormality of the phalanges of the hallux (HP:0010057)2.42019734
36Selective tooth agenesis (HP:0001592)2.41287009
37Nasolacrimal duct obstruction (HP:0000579)2.40941502
38Duplicated collecting system (HP:0000081)2.39613185
3911 pairs of ribs (HP:0000878)2.39482404
40Patellar aplasia (HP:0006443)2.39325075
41Obstructive sleep apnea (HP:0002870)2.38149430
42Colon cancer (HP:0003003)2.36293741
43Abnormality of the duodenum (HP:0002246)2.35927395
44Prominent nose (HP:0000448)2.35001715
45Hypoplasia of the pons (HP:0012110)2.34913785
46Mesomelia (HP:0003027)2.32261773
47Abnormal spermatogenesis (HP:0008669)2.28278030
48Abnormality of the renal collecting system (HP:0004742)2.28168657
49Meckel diverticulum (HP:0002245)2.27713082
50Abnormality of the carotid arteries (HP:0005344)2.27222839
51Nephroblastoma (Wilms tumor) (HP:0002667)2.25838640
52Aplasia/Hypoplasia of the patella (HP:0006498)2.21107924
53Diastasis recti (HP:0001540)2.20481366
54Medulloblastoma (HP:0002885)2.18913646
55Abnormality of the aortic arch (HP:0012303)2.18703302
56Abnormality of homocysteine metabolism (HP:0010919)2.18701785
57Homocystinuria (HP:0002156)2.18701785
58Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.16011319
59Abnormality of the preputium (HP:0100587)2.15571979
60Myelodysplasia (HP:0002863)2.15532077
61Abnormality of male internal genitalia (HP:0000022)2.14792295
62Abnormality of the phalanges of the 5th finger (HP:0004213)2.13374702
63Self-mutilation (HP:0000742)2.13117329
64Abnormality of the ileum (HP:0001549)2.13049970
65Triphalangeal thumb (HP:0001199)2.12301329
66Abnormal number of incisors (HP:0011064)2.11924008
67Cafe-au-lait spot (HP:0000957)2.11788107
68Increased nuchal translucency (HP:0010880)2.10087656
69Embryonal renal neoplasm (HP:0011794)2.10044682
70Progressive muscle weakness (HP:0003323)2.10028505
71Partial agenesis of the corpus callosum (HP:0001338)2.08884164
72Hypoplastic left heart (HP:0004383)2.07140937
73Sandal gap (HP:0001852)2.06230093
74Abnormality of chromosome segregation (HP:0002916)2.02567309
75Abnormality of DNA repair (HP:0003254)2.01560536
76Absent frontal sinuses (HP:0002688)2.00181464
77Acute myeloid leukemia (HP:0004808)1.99510595
78Abnormality of the nasolacrimal system (HP:0000614)1.97376508
79Arteriovenous malformation (HP:0100026)1.96510653
80Abnormal number of erythroid precursors (HP:0012131)1.96401028
81Proximal placement of thumb (HP:0009623)1.96165579
82IgM deficiency (HP:0002850)1.96122472
83Azoospermia (HP:0000027)1.95764889
84Deep philtrum (HP:0002002)1.95498624
85Hypoplastic iliac wings (HP:0002866)1.95404918
86Abnormality of the septum pellucidum (HP:0007375)1.95287350
87Gonadotropin excess (HP:0000837)1.94330222
88Abnormality of the lacrimal duct (HP:0011481)1.93804617
89Aplasia/Hypoplasia of the uvula (HP:0010293)1.93619847
90Duodenal stenosis (HP:0100867)1.92557837
91Small intestinal stenosis (HP:0012848)1.92557837
92Clubbing of toes (HP:0100760)1.91178677
93Breast hypoplasia (HP:0003187)1.90620073
94Premature graying of hair (HP:0002216)1.88793913
95Dislocated radial head (HP:0003083)1.88734163
96Absent thumb (HP:0009777)1.87885831
97Panhypogammaglobulinemia (HP:0003139)1.86740614
98Rhabdomyosarcoma (HP:0002859)1.86032290
99Abnormality of cells of the erythroid lineage (HP:0012130)1.83858676
100Embryonal neoplasm (HP:0002898)1.83639103
101Abnormality of the heme biosynthetic pathway (HP:0010472)1.83420217
102Hypoplasia of the maxilla (HP:0000327)1.83233098
103Absent radius (HP:0003974)1.82981480
104Oral leukoplakia (HP:0002745)1.82804125
105Short thumb (HP:0009778)1.81893404
106Optic nerve coloboma (HP:0000588)1.81535147
107Low anterior hairline (HP:0000294)1.81272805
108Neoplasm of the colon (HP:0100273)1.80472245
109Lip pit (HP:0100267)1.79900740
110Mild short stature (HP:0003502)1.79408374
111Prostate neoplasm (HP:0100787)1.79291491
112Granulocytopenia (HP:0001913)1.79051653
113Septo-optic dysplasia (HP:0100842)1.78455436
114Multiple enchondromatosis (HP:0005701)1.78368904
115Short 5th finger (HP:0009237)1.78138296
116Abnormality of the radial head (HP:0003995)1.77578618
117Macrocytic anemia (HP:0001972)1.76952400
118Deviation of the thumb (HP:0009603)1.76810497
119Septate vagina (HP:0001153)1.76142530
120Congenital, generalized hypertrichosis (HP:0004540)1.76003560
121Facial hemangioma (HP:0000329)1.75563487
122IgA deficiency (HP:0002720)1.74185301
123Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.73565025
124Short 4th metacarpal (HP:0010044)1.73565025
125Basal cell carcinoma (HP:0002671)1.73022849
126Abnormality of the prostate (HP:0008775)1.72767803
127Bone marrow hypocellularity (HP:0005528)1.72226549
128Alveolar cell carcinoma (HP:0006519)1.71348816
129Aplasia/Hypoplasia of the sternum (HP:0006714)1.70705220
130Aseptic necrosis (HP:0010885)1.69752851
131Horseshoe kidney (HP:0000085)1.69700834
132Pallor (HP:0000980)1.68954075
133Carpal bone hypoplasia (HP:0001498)1.68939682
134Optic neuritis (HP:0100653)1.68603614
135Retrobulbar optic neuritis (HP:0100654)1.68603614
136Eosinophilia (HP:0001880)1.67722976
137Abnormality of the distal phalanx of the thumb (HP:0009617)1.67261962
138Aplasia involving forearm bones (HP:0009822)1.66878602
139Cortical dysplasia (HP:0002539)1.66146809
140Supernumerary spleens (HP:0009799)1.66086239
141Anal stenosis (HP:0002025)1.63078455
142Abnormality of cochlea (HP:0000375)1.61408566
143Premature ovarian failure (HP:0008209)1.60066104
144Choanal atresia (HP:0000453)1.60004826
145High anterior hairline (HP:0009890)1.56492935
146Glioma (HP:0009733)1.55258855
147Duplication of thumb phalanx (HP:0009942)1.54721142
148Missing ribs (HP:0000921)1.53795316
149Obsessive-compulsive behavior (HP:0000722)1.53586551
150Malignant gastrointestinal tract tumors (HP:0006749)1.53119559
151Gastrointestinal carcinoma (HP:0002672)1.53119559
152Tracheoesophageal fistula (HP:0002575)1.52910405

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B4.27609709
2MKNK23.84411332
3MKNK13.51605916
4CDC73.51519820
5ZAK3.29133216
6BRD43.01350878
7BUB12.58730201
8ERBB32.56761245
9WEE12.53990622
10VRK12.51839412
11SRPK12.48065862
12NEK22.19345128
13TTK1.89340970
14BRSK21.82595776
15PLK41.79616871
16TAF11.78562502
17PLK31.77694499
18VRK21.77095925
19ATR1.72970400
20PASK1.70295109
21PNCK1.66282621
22PBK1.62465478
23TSSK61.57279010
24CLK11.55071250
25PIK3CA1.47352814
26DYRK31.44975543
27EIF2AK11.40075269
28CHUK1.39678270
29AURKB1.39562003
30PLK11.36417871
31CDK71.35427175
32CCNB11.31473481
33NEK91.24321721
34RPS6KA41.20157553
35NEK11.19310622
36RPS6KB21.18812011
37IRAK41.18173414
38TGFBR11.16223437
39FGFR31.14458631
40STK161.03551848
41TXK1.02640340
42TNIK1.02241697
43MAP3K141.01214526
44CAMK1D1.00759110
45CHEK10.99628677
46CAMK1G0.98283864
47EIF2AK30.97132452
48STK40.97051262
49TEC0.96035934
50SIK20.95687880
51TRPM70.91412767
52FLT30.88528027
53PRPF4B0.87252366
54TLK10.85602144
55ATM0.84196417
56CAMK40.84126300
57FRK0.83418394
58BMPR1B0.81640205
59SMG10.81330292
60YES10.80773823
61CHEK20.80356094
62* CDK20.78828695
63PIM10.78763975
64BRSK10.75536447
65NEK60.73405655
66SGK20.72771574
67EIF2AK20.69553650
68NME20.69368554
69STK30.69123165
70STK100.69044125
71JAK30.67931804
72CDK120.64954171
73PDGFRA0.64619986
74NME10.62743159
75CDK80.62087288
76DYRK1A0.60786720
77MAP3K80.59659310
78MST40.59601260
79TESK10.58673653
80MST1R0.58387578
81ALK0.58145279
82IKBKB0.57975745
83CDK40.57377774
84* CDK10.56327905
85BTK0.56300725
86CSNK2A10.55687941
87STK38L0.55270637
88MAP2K20.55074356
89NUAK10.53993786
90PAK40.50708318
91SCYL20.50285097
92TAOK20.49001687
93MTOR0.46934634
94CSNK2A20.46881793
95RPS6KA50.46052792
96MAP4K10.45388417
97TIE10.44796495
98CDK90.43796648
99AURKA0.43776667
100AKT30.42592776
101KIT0.42396392
102CDK30.41705708
103RPS6KB10.40865639
104PDK20.39022494
105PDGFRB0.38867484
106IKBKE0.38810645
107LATS10.38767248
108MAP3K100.38752284
109MAPK110.38315480
110* AKT10.38178977
111SGK30.37129352
112* GSK3B0.35834147
113RPS6KA10.35533589
114MELK0.35454677
115MAPK150.35419313
116PRKDC0.34675407
117EEF2K0.34490765
118CSNK1E0.34378212
119STK240.34335448
120EPHA20.33633895
121NLK0.32319123
122* MAPK140.31812514
123CDK60.31000541
124UHMK10.28877741
125MARK30.26961258
126TRIM280.22647671
127MAPK10.21590619
128MAP3K40.21047525
129MAPK100.20783183
130DYRK20.18482681

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.54013868
2Mismatch repair_Homo sapiens_hsa034303.83356878
3Base excision repair_Homo sapiens_hsa034103.53521527
4* Spliceosome_Homo sapiens_hsa030403.31469629
5Homologous recombination_Homo sapiens_hsa034402.98548343
6Cyanoamino acid metabolism_Homo sapiens_hsa004602.81649340
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.71666353
8Cell cycle_Homo sapiens_hsa041102.62095994
9RNA transport_Homo sapiens_hsa030132.55324112
10Nucleotide excision repair_Homo sapiens_hsa034202.44820419
11RNA polymerase_Homo sapiens_hsa030202.40307552
12One carbon pool by folate_Homo sapiens_hsa006702.40250435
13Fanconi anemia pathway_Homo sapiens_hsa034602.29051040
14RNA degradation_Homo sapiens_hsa030182.09823390
15Ribosome_Homo sapiens_hsa030102.08422956
16Pyrimidine metabolism_Homo sapiens_hsa002401.98541940
17Basal transcription factors_Homo sapiens_hsa030221.82475424
18Non-homologous end-joining_Homo sapiens_hsa034501.78894050
19Proteasome_Homo sapiens_hsa030501.76320247
20mRNA surveillance pathway_Homo sapiens_hsa030151.66982620
21p53 signaling pathway_Homo sapiens_hsa041151.65938769
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.61573952
23Herpes simplex infection_Homo sapiens_hsa051681.60033250
24Lysine degradation_Homo sapiens_hsa003101.27630507
25TGF-beta signaling pathway_Homo sapiens_hsa043501.27252779
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.22622143
27Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.22511754
28Notch signaling pathway_Homo sapiens_hsa043301.18423353
29Systemic lupus erythematosus_Homo sapiens_hsa053221.17476447
30Epstein-Barr virus infection_Homo sapiens_hsa051691.15747476
31Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12950662
32Viral carcinogenesis_Homo sapiens_hsa052031.12935913
33Legionellosis_Homo sapiens_hsa051341.09118285
34Purine metabolism_Homo sapiens_hsa002301.08690098
35HTLV-I infection_Homo sapiens_hsa051661.08371107
36MicroRNAs in cancer_Homo sapiens_hsa052061.06745786
37NF-kappa B signaling pathway_Homo sapiens_hsa040640.98857922
38Cysteine and methionine metabolism_Homo sapiens_hsa002700.98467262
39Antigen processing and presentation_Homo sapiens_hsa046120.97531100
40Primary immunodeficiency_Homo sapiens_hsa053400.95472611
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.91215010
42Small cell lung cancer_Homo sapiens_hsa052220.90519130
43Hepatitis B_Homo sapiens_hsa051610.90018609
44Protein export_Homo sapiens_hsa030600.86676286
45Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.86510782
46Prostate cancer_Homo sapiens_hsa052150.86202913
47Arachidonic acid metabolism_Homo sapiens_hsa005900.82412068
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79606082
49Measles_Homo sapiens_hsa051620.76925739
50Thyroid cancer_Homo sapiens_hsa052160.74378019
51Influenza A_Homo sapiens_hsa051640.72545173
52Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.67789057
53Hematopoietic cell lineage_Homo sapiens_hsa046400.67545048
54Apoptosis_Homo sapiens_hsa042100.65862002
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62235465
56Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.61876208
57NOD-like receptor signaling pathway_Homo sapiens_hsa046210.61616256
58Drug metabolism - other enzymes_Homo sapiens_hsa009830.60220252
59Adherens junction_Homo sapiens_hsa045200.60129556
60RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.59885825
61Basal cell carcinoma_Homo sapiens_hsa052170.59343908
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.58067230
63Selenocompound metabolism_Homo sapiens_hsa004500.55170293
64Colorectal cancer_Homo sapiens_hsa052100.53364519
65Pathways in cancer_Homo sapiens_hsa052000.51637323
66Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.51505905
67Wnt signaling pathway_Homo sapiens_hsa043100.51465208
68Oocyte meiosis_Homo sapiens_hsa041140.50910870
69Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49006183
70Leishmaniasis_Homo sapiens_hsa051400.47779712
71Alcoholism_Homo sapiens_hsa050340.46896358
72Shigellosis_Homo sapiens_hsa051310.46590513
73Hippo signaling pathway_Homo sapiens_hsa043900.44390957
74Biosynthesis of amino acids_Homo sapiens_hsa012300.44221102
75Chronic myeloid leukemia_Homo sapiens_hsa052200.44168470
76Melanoma_Homo sapiens_hsa052180.43597863
77Allograft rejection_Homo sapiens_hsa053300.41647040
78Bladder cancer_Homo sapiens_hsa052190.41610563
79Huntingtons disease_Homo sapiens_hsa050160.41194014
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40126084
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.39577568
82Caffeine metabolism_Homo sapiens_hsa002320.38719988
83FoxO signaling pathway_Homo sapiens_hsa040680.37605483
84N-Glycan biosynthesis_Homo sapiens_hsa005100.36998032
85Viral myocarditis_Homo sapiens_hsa054160.35867576
86Jak-STAT signaling pathway_Homo sapiens_hsa046300.35856250
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35670856
88Acute myeloid leukemia_Homo sapiens_hsa052210.33676609
89Hedgehog signaling pathway_Homo sapiens_hsa043400.33646000
90TNF signaling pathway_Homo sapiens_hsa046680.33180043
91Non-small cell lung cancer_Homo sapiens_hsa052230.33072568
92Graft-versus-host disease_Homo sapiens_hsa053320.32246931
93B cell receptor signaling pathway_Homo sapiens_hsa046620.32077596
94Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.31815225
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.31465435
96HIF-1 signaling pathway_Homo sapiens_hsa040660.31046216
97Toxoplasmosis_Homo sapiens_hsa051450.30271839
98Glutathione metabolism_Homo sapiens_hsa004800.28878772
99PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28011143
100Endometrial cancer_Homo sapiens_hsa052130.27449890
101Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25915661
102Asthma_Homo sapiens_hsa053100.25827014
103T cell receptor signaling pathway_Homo sapiens_hsa046600.25014772
104Pancreatic cancer_Homo sapiens_hsa052120.24747500
105Autoimmune thyroid disease_Homo sapiens_hsa053200.24126317
106Renal cell carcinoma_Homo sapiens_hsa052110.22376891
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.22030952
108Thyroid hormone signaling pathway_Homo sapiens_hsa049190.21325884
109Folate biosynthesis_Homo sapiens_hsa007900.21244912
110Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.20718026
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.20671144
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20138385
113Steroid biosynthesis_Homo sapiens_hsa001000.20033520
114Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19361690
115Pyruvate metabolism_Homo sapiens_hsa006200.18901438
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17815528
117Central carbon metabolism in cancer_Homo sapiens_hsa052300.15324905
118Circadian rhythm_Homo sapiens_hsa047100.15143333
119Prolactin signaling pathway_Homo sapiens_hsa049170.14927478
120Propanoate metabolism_Homo sapiens_hsa006400.14711829
121Sulfur relay system_Homo sapiens_hsa041220.13370536
122Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.10788254
123ErbB signaling pathway_Homo sapiens_hsa040120.09231577
124Vitamin digestion and absorption_Homo sapiens_hsa049770.08278453
125Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.06864392
126Glioma_Homo sapiens_hsa052140.06121221

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