TRAFD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.11276262
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.11276262
3antigen processing and presentation of endogenous antigen (GO:0019883)5.82421883
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.91919756
5response to type I interferon (GO:0034340)4.82475683
6type I interferon signaling pathway (GO:0060337)4.81959969
7cellular response to type I interferon (GO:0071357)4.81959969
8positive regulation by symbiont of host defense response (GO:0052509)4.80042769
9modulation by symbiont of host defense response (GO:0052031)4.80042769
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.80042769
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.80042769
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.80042769
13modulation by symbiont of host immune response (GO:0052553)4.80042769
14positive regulation of interferon-alpha production (GO:0032727)4.76531313
15regulation of interferon-alpha production (GO:0032647)4.48500553
16positive regulation of gamma-delta T cell activation (GO:0046645)4.27742604
17negative regulation of interleukin-12 production (GO:0032695)4.21515761
18positive regulation of type I interferon-mediated signaling pathway (GO:0060340)4.21504274
19detection of other organism (GO:0098543)4.14297444
20regulation of interferon-beta biosynthetic process (GO:0045357)4.13898567
21NIK/NF-kappaB signaling (GO:0038061)4.02472868
22detection of bacterium (GO:0016045)3.97314413
23response to interferon-alpha (GO:0035455)3.88679030
24interferon-gamma-mediated signaling pathway (GO:0060333)3.85931153
25positive regulation of type 2 immune response (GO:0002830)3.84157333
26immunoglobulin mediated immune response (GO:0016064)3.75577084
27positive regulation of natural killer cell differentiation (GO:0032825)3.74527268
28regulation of T cell tolerance induction (GO:0002664)3.74146042
29antigen processing and presentation via MHC class Ib (GO:0002475)3.68862990
30regulation of interleukin-12 biosynthetic process (GO:0045075)3.68825584
31negative regulation of T cell mediated immunity (GO:0002710)3.64780519
32positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.63556431
33macrophage activation involved in immune response (GO:0002281)3.61554806
34response to muramyl dipeptide (GO:0032495)3.55482948
35response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.52568427
36response to host immune response (GO:0052572)3.52568427
37positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.49660459
38positive regulation of antigen processing and presentation (GO:0002579)3.47816838
39negative regulation of lymphocyte mediated immunity (GO:0002707)3.43372063
40JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.41975843
41response to peptidoglycan (GO:0032494)3.37912304
42regulation of type I interferon-mediated signaling pathway (GO:0060338)3.36330224
43detection of external biotic stimulus (GO:0098581)3.33210176
44regulation of tolerance induction (GO:0002643)3.28630155
45regulation of RIG-I signaling pathway (GO:0039535)3.28033821
46regulation of dendritic cell antigen processing and presentation (GO:0002604)3.27737421
47response to interleukin-15 (GO:0070672)3.27508988
48germinal center formation (GO:0002467)3.22696602
49natural killer cell mediated cytotoxicity (GO:0042267)3.22507944
50natural killer cell mediated immunity (GO:0002228)3.22507944
51response to host (GO:0075136)3.22308476
52response to host defenses (GO:0052200)3.22308476
53response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.22308476
54leukocyte aggregation (GO:0070486)3.21594360
55negative regulation of viral genome replication (GO:0045071)3.19028053
56cellular response to interleukin-15 (GO:0071350)3.17169494
57cellular response to virus (GO:0098586)3.16588351
58regulation of type 2 immune response (GO:0002828)3.15436366
59positive regulation of interferon-beta production (GO:0032728)3.14216602
60regulation of cholesterol storage (GO:0010885)3.12606549
61detection of molecule of bacterial origin (GO:0032490)3.11975482
62response to protozoan (GO:0001562)3.10388274
63regulation of alpha-beta T cell proliferation (GO:0046640)3.09671915
64negative regulation of leukocyte mediated immunity (GO:0002704)3.04800409
65regulation of regulatory T cell differentiation (GO:0045589)3.03999915
66neutrophil activation involved in immune response (GO:0002283)3.02127109
67production of molecular mediator involved in inflammatory response (GO:0002532)3.01734686
68low-density lipoprotein particle clearance (GO:0034383)3.00861382
69dendritic cell chemotaxis (GO:0002407)2.99615556
70natural killer cell activation involved in immune response (GO:0002323)2.99552198
71regulation of gamma-delta T cell activation (GO:0046643)2.99400497
72myeloid dendritic cell differentiation (GO:0043011)2.97837530
73positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.96580724
74lipopolysaccharide-mediated signaling pathway (GO:0031663)2.96311181
75B cell receptor signaling pathway (GO:0050853)2.96100827
76growth hormone receptor signaling pathway (GO:0060396)2.95853326
77cellular response to interferon-alpha (GO:0035457)2.94236336
78regulation of natural killer cell mediated immunity (GO:0002715)2.91326490
79regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.91326490
80cellular extravasation (GO:0045123)2.91129924
81negative thymic T cell selection (GO:0045060)2.89416598
82cellular response to interferon-gamma (GO:0071346)2.89401738
83regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.89327624
84negative T cell selection (GO:0043383)2.88580164
85positive regulation of tolerance induction (GO:0002645)2.88531264
86negative regulation of cytokine production involved in immune response (GO:0002719)2.88450812
87detection of biotic stimulus (GO:0009595)2.86054686
88interferon-gamma secretion (GO:0072643)2.84891759
89positive regulation of humoral immune response (GO:0002922)2.84833131
90regulation of antigen processing and presentation (GO:0002577)2.82207089
91regulation of gamma-delta T cell differentiation (GO:0045586)2.80471097
92positive regulation of B cell differentiation (GO:0045579)2.79875911
93regulation of T-helper 1 cell differentiation (GO:0045625)2.78336170
94positive regulation of response to cytokine stimulus (GO:0060760)2.74212736
95myeloid dendritic cell activation (GO:0001773)2.73201882
96microglial cell activation (GO:0001774)2.70950117
97regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.70792773
98T-helper 1 type immune response (GO:0042088)2.69899414
99dendritic cell differentiation (GO:0097028)2.67141671
100cellular response to exogenous dsRNA (GO:0071360)2.66116807
101positive regulation of cytokine-mediated signaling pathway (GO:0001961)2.65767914
102sperm motility (GO:0030317)2.65731683
103regulation of B cell receptor signaling pathway (GO:0050855)2.65714636
104positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.64768506
105regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.62412359
106regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.60603691
107positive regulation of interleukin-12 production (GO:0032735)2.59413686
108positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.58984254
109regulation of response to interferon-gamma (GO:0060330)2.58336787
110response to interferon-gamma (GO:0034341)2.58048916
111defense response to protozoan (GO:0042832)2.57332417
112I-kappaB phosphorylation (GO:0007252)2.56596770
113JAK-STAT cascade (GO:0007259)2.55861613
114positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.55388574
115regulation of natural killer cell differentiation (GO:0032823)2.54742709
116T cell migration (GO:0072678)2.54599832
117granulocyte activation (GO:0036230)2.54006336
118B cell mediated immunity (GO:0019724)2.52229827
119cellular response to interferon-beta (GO:0035458)2.51468811
120regulation of necroptotic process (GO:0060544)2.48924656
121cellular response to growth hormone stimulus (GO:0071378)2.48333644
122macrophage activation (GO:0042116)2.46048897
123lymphocyte chemotaxis (GO:0048247)2.45075118
124neutrophil activation (GO:0042119)2.44678274
125positive regulation of chemokine biosynthetic process (GO:0045080)2.44427833
126respiratory burst (GO:0045730)2.44395687
127membrane protein intracellular domain proteolysis (GO:0031293)2.40922821
128regulation of interleukin-12 production (GO:0032655)2.40756830
129fusion of sperm to egg plasma membrane (GO:0007342)2.40175081
130myeloid cell activation involved in immune response (GO:0002275)2.39353012
131regulation of interferon-beta production (GO:0032648)2.38328076
132negative regulation of lipid storage (GO:0010888)2.38040505
133negative regulation of cell killing (GO:0031342)2.38009669
134negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.38009669
135natural killer cell differentiation (GO:0001779)2.36967333
136response to interferon-beta (GO:0035456)2.36654644

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.08938658
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.73778657
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.46563004
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.31717628
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.28256439
6* IRF8_27001747_Chip-Seq_BMDM_Mouse3.24991749
7SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.83117870
8NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.76833105
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.74830064
10STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.58494588
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.32896247
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.32021549
13Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.28073086
14* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.23005318
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.17231208
16* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.07347685
17THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.01278786
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.00496538
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.93213372
20RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.88862061
21STAT4_19710469_ChIP-ChIP_TH1__Mouse1.88406415
22PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.84122971
23SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.82948645
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.78266608
25BRD4_27068464_Chip-Seq_AML-cells_Mouse1.74497280
26EGR1_19374776_ChIP-ChIP_THP-1_Human1.72682879
27TCF7_22412390_ChIP-Seq_EML_Mouse1.70831427
28MAF_26560356_Chip-Seq_TH1_Human1.69444684
29SMAD_19615063_ChIP-ChIP_OVARY_Human1.66832063
30SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.66820699
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64388603
32RXR_22158963_ChIP-Seq_LIVER_Mouse1.63519790
33SPI1_23127762_ChIP-Seq_K562_Human1.63061979
34NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.62281926
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.61843026
36SCL_19346495_ChIP-Seq_HPC-7_Human1.57777544
37FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.57441351
38PPARA_22158963_ChIP-Seq_LIVER_Mouse1.57405896
39PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.57052907
40RUNX_20019798_ChIP-Seq_JUKART_Human1.56466871
41VDR_21846776_ChIP-Seq_THP-1_Human1.54167977
42CIITA_25753668_ChIP-Seq_RAJI_Human1.52825457
43* LXR_22158963_ChIP-Seq_LIVER_Mouse1.46179875
44* MYB_26560356_Chip-Seq_TH2_Human1.44851277
45KDM2B_26808549_Chip-Seq_SUP-B15_Human1.44649767
46BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.44301480
47VDR_24763502_ChIP-Seq_THP-1_Human1.43456169
48E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.42104672
49VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.38277420
50VDR_24787735_ChIP-Seq_THP-1_Human1.37654681
51GATA1_22025678_ChIP-Seq_K562_Human1.36671920
52MYB_26560356_Chip-Seq_TH1_Human1.35789254
53RUNX1_22412390_ChIP-Seq_EML_Mouse1.35094694
54TFEB_21752829_ChIP-Seq_HELA_Human1.34931876
55* KDM2B_26808549_Chip-Seq_DND41_Human1.33137712
56* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.32953293
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.32826428
58CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.32449321
59PU_27001747_Chip-Seq_BMDM_Mouse1.31588538
60NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.31220753
61LXR_22292898_ChIP-Seq_THP-1_Human1.28946999
62KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.28726800
63PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.28212896
64CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27995094
65* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.27668414
66* UTX_26944678_Chip-Seq_JUKART_Human1.27052226
67MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.26221493
68ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26221322
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.24478886
70GATA2_21666600_ChIP-Seq_HMVEC_Human1.22335280
71GATA1_19941827_ChIP-Seq_MEL_Mouse1.21928538
72KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20347516
73NOTCH1_21737748_ChIP-Seq_TLL_Human1.17841683
74GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.16825001
75GATA3_27048872_Chip-Seq_THYMUS_Human1.16355754
76FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.15078298
77* SPI1_23547873_ChIP-Seq_NB4_Human1.14795722
78ELK3_25401928_ChIP-Seq_HUVEC_Human1.13721501
79LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.13571784
80SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.13537754
81PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13038418
82TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12201810
83PU.1_20513432_ChIP-Seq_Bcells_Mouse1.09603361
84MYC_22102868_ChIP-Seq_BL_Human1.09145997
85NCOR1_26117541_ChIP-Seq_K562_Human1.08740230
86CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08496604
87MAF_26560356_Chip-Seq_TH2_Human1.07402156
88GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06789353
89PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04162214
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01481984
91GATA1_19941826_ChIP-Seq_K562_Human1.00799111
92* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.99829077
93SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99585040
94SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98229666
95TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97762534
96LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.97668871
97ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96678420
98CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96667537
99GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96366221
100STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95613536
101* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.94301617
102BCL6_27268052_Chip-Seq_Bcells_Human0.92537275
103ELF1_20517297_ChIP-Seq_JURKAT_Human0.89108147
104* GATA3_26560356_Chip-Seq_TH2_Human0.88875536
105GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86425456
106IKZF1_21737484_ChIP-ChIP_HCT116_Human0.86161661
107EGR1_19032775_ChIP-ChIP_M12_Human0.84999703
108BCOR_27268052_Chip-Seq_Bcells_Human0.84835921
109CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.84665882
110EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.84468266
111TBX20_22080862_ChIP-Seq_HEART_Mouse0.84457549
112TBX20_22328084_ChIP-Seq_HEART_Mouse0.84457549
113* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84296744
114MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.84254224
115SRY_22984422_ChIP-ChIP_TESTIS_Rat0.81947092
116CTCF_27219007_Chip-Seq_ERYTHROID_Human0.81911844
117EGR1_23403033_ChIP-Seq_LIVER_Mouse0.81557832
118TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81031384
119* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80606318
120KDM2B_26808549_Chip-Seq_JURKAT_Human0.79998303
121GATA2_19941826_ChIP-Seq_K562_Human0.79938238
122MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.79047421
123KDM2B_26808549_Chip-Seq_K562_Human0.78247592
124RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.77595248
125* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77026706

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.25111475
2MP0003436_decreased_susceptibility_to3.38123510
3MP0004510_myositis3.33880754
4MP0003303_peritoneal_inflammation3.10653614
5MP0009785_altered_susceptibility_to3.01850336
6MP0000685_abnormal_immune_system2.98760045
7MP0005387_immune_system_phenotype2.77004648
8MP0001790_abnormal_immune_system2.77004648
9* MP0005025_abnormal_response_to2.45411115
10MP0005000_abnormal_immune_tolerance2.45247512
11MP0002419_abnormal_innate_immunity2.43814090
12MP0005671_abnormal_response_to2.36679634
13MP0001800_abnormal_humoral_immune2.31081926
14MP0008260_abnormal_autophagy2.26389853
15MP0003011_delayed_dark_adaptation2.25717494
16MP0003724_increased_susceptibility_to2.24847319
17MP0002148_abnormal_hypersensitivity_rea2.24282451
18MP0002452_abnormal_antigen_presenting2.23309945
19MP0006082_CNS_inflammation2.22297505
20MP0005058_abnormal_lysosome_morphology2.21539646
21MP0005410_abnormal_fertilization2.18464812
22MP0005451_abnormal_body_composition2.14189417
23* MP0002723_abnormal_immune_serum2.10412461
24MP0009840_abnormal_foam_cell2.07738531
25MP0003191_abnormal_cellular_cholesterol2.03085559
26MP0002166_altered_tumor_susceptibility2.00578666
27MP0000569_abnormal_digit_pigmentation2.00465760
28MP0004947_skin_inflammation1.93588825
29MP0001819_abnormal_immune_cell1.89826312
30MP0003172_abnormal_lysosome_physiology1.86102828
31MP0002420_abnormal_adaptive_immunity1.85053336
32MP0005464_abnormal_platelet_physiology1.83531336
33MP0003300_gastrointestinal_ulcer1.80340907
34MP0001533_abnormal_skeleton_physiology1.79138668
35MP0002138_abnormal_hepatobiliary_system1.67849763
36MP0002254_reproductive_system_inflammat1.62639118
37MP0009764_decreased_sensitivity_to1.61428161
38* MP0001845_abnormal_inflammatory_respons1.56994944
39MP0002006_tumorigenesis1.56300254
40MP0009278_abnormal_bone_marrow1.54793209
41* MP0008469_abnormal_protein_level1.54533777
42MP0002405_respiratory_system_inflammati1.49660048
43MP0005310_abnormal_salivary_gland1.47833195
44MP0001853_heart_inflammation1.45595505
45MP0010155_abnormal_intestine_physiology1.45591905
46MP0003221_abnormal_cardiomyocyte_apopto1.45226042
47MP0000716_abnormal_immune_system1.43295983
48MP0000343_altered_response_to1.42313407
49MP0000703_abnormal_thymus_morphology1.41766954
50MP0004130_abnormal_muscle_cell1.41555105
51MP0000604_amyloidosis1.40518901
52MP0002398_abnormal_bone_marrow1.39408004
53MP0001545_abnormal_hematopoietic_system1.38415188
54MP0005397_hematopoietic_system_phenotyp1.38415188
55MP0003705_abnormal_hypodermis_morpholog1.36035500
56MP0003075_altered_response_to1.35904390
57MP0003183_abnormal_peptide_metabolism1.28478364
58MP0003448_altered_tumor_morphology1.27705908
59MP0003866_abnormal_defecation1.24530545
60MP0005551_abnormal_eye_electrophysiolog1.18415346
61MP0003656_abnormal_erythrocyte_physiolo1.16892950
62MP0002998_abnormal_bone_remodeling1.14041413
63MP0002429_abnormal_blood_cell1.13712336
64MP0003045_fibrosis1.12687154
65MP0005076_abnormal_cell_differentiation1.08413722
66MP0000689_abnormal_spleen_morphology1.07305377
67MP0003646_muscle_fatigue1.04317530
68MP0000609_abnormal_liver_physiology1.03568615
69MP0002132_abnormal_respiratory_system1.01173755
70MP0001873_stomach_inflammation1.00115961
71MP0002722_abnormal_immune_system0.99050424
72MP0010329_abnormal_lipoprotein_level0.98560599
73MP0003690_abnormal_glial_cell0.97729953
74* MP0009763_increased_sensitivity_to0.93578232
75MP0010307_abnormal_tumor_latency0.93331690
76MP0009765_abnormal_xenobiotic_induced0.92866680
77MP0002277_abnormal_respiratory_mucosa0.92766632
78MP0003091_abnormal_cell_migration0.92701221
79MP0005360_urolithiasis0.92390331
80MP0004858_abnormal_nervous_system0.91986847
81MP0000490_abnormal_crypts_of0.91908054
82MP0004808_abnormal_hematopoietic_stem0.91672026
83MP0003252_abnormal_bile_duct0.91567690
84MP0005166_decreased_susceptibility_to0.90824037
85MP0002139_abnormal_hepatobiliary_system0.90241405
86MP0003763_abnormal_thymus_physiology0.89792950
87MP0002090_abnormal_vision0.89163513
88MP0004782_abnormal_surfactant_physiolog0.88987370
89MP0008961_abnormal_basal_metabolism0.88873890
90MP0004883_abnormal_blood_vessel0.87707055
91MP0003566_abnormal_cell_adhesion0.86894686
92MP0000858_altered_metastatic_potential0.84885684
93MP0008004_abnormal_stomach_pH0.83977661
94MP0009333_abnormal_splenocyte_physiolog0.83615417
95MP0002933_joint_inflammation0.82608142
96MP0002971_abnormal_brown_adipose0.80698014
97MP0002332_abnormal_exercise_endurance0.80450788
98MP0000465_gastrointestinal_hemorrhage0.79789226
99MP0005253_abnormal_eye_physiology0.79544444
100MP0005365_abnormal_bile_salt0.79160044
101MP0009115_abnormal_fat_cell0.79108421
102MP0008874_decreased_physiological_sensi0.77929220
103MP0003828_pulmonary_edema0.77593885
104MP0000249_abnormal_blood_vessel0.76973891
105MP0001324_abnormal_eye_pigmentation0.74031037
106MP0001851_eye_inflammation0.73764584
107MP0002877_abnormal_melanocyte_morpholog0.73008272
108MP0005670_abnormal_white_adipose0.72617389
109MP0003453_abnormal_keratinocyte_physiol0.71013655
110MP0002019_abnormal_tumor_incidence0.69349228
111MP0005666_abnormal_adipose_tissue0.69112402
112* MP0005319_abnormal_enzyme/_coenzyme0.68481429
113MP0005390_skeleton_phenotype0.68476834
114MP0003806_abnormal_nucleotide_metabolis0.65362520
115MP0005083_abnormal_biliary_tract0.65160259
116MP0005164_abnormal_response_to0.65058644
117MP0003329_amyloid_beta_deposits0.64834632
118MP0002118_abnormal_lipid_homeostasis0.64364733
119MP0002928_abnormal_bile_duct0.64131769
120MP0000598_abnormal_liver_morphology0.64036000
121MP0000767_abnormal_smooth_muscle0.63887050
122MP0004381_abnormal_hair_follicle0.63651147
123MP0003795_abnormal_bone_structure0.63611660
124MP0001663_abnormal_digestive_system0.62683440
125MP0002653_abnormal_ependyma_morphology0.59917482
126MP0002396_abnormal_hematopoietic_system0.58486576
127MP0000313_abnormal_cell_death0.55691398
128MP0005621_abnormal_cell_physiology0.54044756
129MP0005584_abnormal_enzyme/coenzyme_acti0.45371774
130MP0000920_abnormal_myelination0.45059428
131MP0005075_abnormal_melanosome_morpholog0.43116993
132MP0010234_abnormal_vibrissa_follicle0.42566482

Predicted human phenotypes

RankGene SetZ-score
1Nasal polyposis (HP:0100582)5.31792997
2Abnormality of the nasal mucosa (HP:0000433)4.89133176
3Eczematoid dermatitis (HP:0000976)4.60301583
4Recurrent abscess formation (HP:0002722)4.25973468
5Recurrent bacterial skin infections (HP:0005406)4.18567146
6Recurrent gram-negative bacterial infections (HP:0005420)4.07983087
7Chronic otitis media (HP:0000389)4.00817473
8Stomatitis (HP:0010280)3.85992789
9Pigmentary retinal degeneration (HP:0001146)3.80857647
10Meningitis (HP:0001287)3.63693247
11Chronic obstructive pulmonary disease (HP:0006510)3.60995673
12Obstructive lung disease (HP:0006536)3.60995673
13Keratoconjunctivitis sicca (HP:0001097)3.60635068
14Myositis (HP:0100614)3.58775189
15Congenital stationary night blindness (HP:0007642)3.55453252
16Systemic lupus erythematosus (HP:0002725)3.54809332
17Encephalitis (HP:0002383)3.47062109
18Elevated erythrocyte sedimentation rate (HP:0003565)3.46582565
19Recurrent bronchitis (HP:0002837)3.42470859
20Autoimmune thrombocytopenia (HP:0001973)3.42264043
21T lymphocytopenia (HP:0005403)3.38046046
22Orchitis (HP:0100796)3.36557203
23Increased cerebral lipofuscin (HP:0011813)3.30197481
24Keratoconjunctivitis (HP:0001096)3.24123484
25Petechiae (HP:0000967)3.17871015
26Interstitial pulmonary disease (HP:0006530)3.12370512
27Abnormality of T cell number (HP:0011839)3.12016174
28Urticaria (HP:0001025)3.11649367
29Recurrent fungal infections (HP:0002841)3.11089168
30Colitis (HP:0002583)3.00633964
31Mediastinal lymphadenopathy (HP:0100721)2.99729975
32Bony spicule pigmentary retinopathy (HP:0007737)2.96264536
33Chest pain (HP:0100749)2.95319126
34Abnormality of macrophages (HP:0004311)2.94477413
35Recurrent skin infections (HP:0001581)2.93414469
36Abnormal gallbladder physiology (HP:0012438)2.86433447
37Cholecystitis (HP:0001082)2.86433447
38Optic neuritis (HP:0100653)2.85507541
39Retrobulbar optic neuritis (HP:0100654)2.85507541
40Loss of speech (HP:0002371)2.85210574
41Recurrent viral infections (HP:0004429)2.83385952
42Dyschromatopsia (HP:0007641)2.78975464
43Vasculitis (HP:0002633)2.77961012
44Leukocytosis (HP:0001974)2.71579580
45Increased neuronal autofluorescent lipopigment (HP:0002074)2.71060969
46Bronchitis (HP:0012387)2.69277748
47Lymphopenia (HP:0001888)2.66623463
48Gingivitis (HP:0000230)2.66471935
49Chronic mucocutaneous candidiasis (HP:0002728)2.65541523
50Recurrent cutaneous fungal infections (HP:0011370)2.65541523
51Abnormality of T cells (HP:0002843)2.61398844
52Tetraparesis (HP:0002273)2.58796106
53Arterial thrombosis (HP:0004420)2.56548354
54Complement deficiency (HP:0004431)2.55760860
55Periodontitis (HP:0000704)2.54800180
56Chronic sinusitis (HP:0011109)2.53313171
57Hematochezia (HP:0002573)2.52012121
58Gangrene (HP:0100758)2.51950911
59Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.51844973
60Myocardial infarction (HP:0001658)2.51685963
61Abnormality of cells of the lymphoid lineage (HP:0012140)2.49249336
62Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.49002597
63Glomerulonephritis (HP:0000099)2.48166883
64Absent rod-and cone-mediated responses on ERG (HP:0007688)2.47440593
65Purpura (HP:0000979)2.45232604
66Dynein arm defect of respiratory motile cilia (HP:0012255)2.45030812
67Absent/shortened dynein arms (HP:0200106)2.45030812
68Vacuolated lymphocytes (HP:0001922)2.44341285
69Anorexia (HP:0002039)2.43190081
70Macular degeneration (HP:0000608)2.42527120
71Abnormal rod and cone electroretinograms (HP:0008323)2.42273055
72Granulocytopenia (HP:0001913)2.42202260
73Central scotoma (HP:0000603)2.41397687
74Prolonged bleeding time (HP:0003010)2.40073327
75Hypergammaglobulinemia (HP:0010702)2.39724580
76Amaurosis fugax (HP:0100576)2.38674059
77Abolished electroretinogram (ERG) (HP:0000550)2.38400003
78Increased IgE level (HP:0003212)2.37740219
79Panhypogammaglobulinemia (HP:0003139)2.34889385
80Inflammation of the large intestine (HP:0002037)2.34668808
81Abnormality of the pleura (HP:0002103)2.29914628
82Progressive visual loss (HP:0000529)2.29707178
83Gastrointestinal inflammation (HP:0004386)2.29627421
84Pulmonary infiltrates (HP:0002113)2.27503102
85Hepatosplenomegaly (HP:0001433)2.27434769
86Sepsis (HP:0100806)2.25549357
87IgM deficiency (HP:0002850)2.24348596
88Gingival bleeding (HP:0000225)2.20185346
89Epistaxis (HP:0000421)2.19953857
90Abnormality of complement system (HP:0005339)2.19633578
91Premature loss of primary teeth (HP:0006323)2.19619673
92Autoimmune hemolytic anemia (HP:0001890)2.19564483
93Chorioretinal atrophy (HP:0000533)2.18702757
94Cellulitis (HP:0100658)2.18169507
95Retinal atrophy (HP:0001105)2.17208463
96Constricted visual fields (HP:0001133)2.16900325
97Nephritis (HP:0000123)2.16452489
98Recurrent sinusitis (HP:0011108)2.15734493
99Asymmetric septal hypertrophy (HP:0001670)2.15147841
100Chronic diarrhea (HP:0002028)2.13413394
101Agammaglobulinemia (HP:0004432)2.12715005
102Hypertensive crisis (HP:0100735)2.12478544
103Thick nail (HP:0001805)2.12245532
104IgA deficiency (HP:0002720)2.09771457
105Frequent falls (HP:0002359)2.09735518
106Eosinophilia (HP:0001880)2.08932385
107Joint swelling (HP:0001386)2.08886272
108Keratitis (HP:0000491)2.07957573
109Emphysema (HP:0002097)2.07477613
110Glomerulopathy (HP:0100820)2.07283296
111Abnormality of liposaccharide metabolism (HP:0010968)2.06369281
112Abnormality of glycosphingolipid metabolism (HP:0004343)2.06369281
113Abnormality of glycolipid metabolism (HP:0010969)2.06369281
114Pulmonary embolism (HP:0002204)2.04508842
115Episodic fever (HP:0001954)2.04209312
116Pendular nystagmus (HP:0012043)2.03237089
117Abnormality of the endocardium (HP:0004306)2.02725139
118Skin ulcer (HP:0200042)2.00764584
119Increased serum ferritin (HP:0003281)1.99904024
120Abnormality of T cell physiology (HP:0011840)1.99775519
121Malnutrition (HP:0004395)1.99571852
122Scotoma (HP:0000575)1.99549038
123Fatigue (HP:0012378)1.98720080
124Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.97975711
125Abnormality of macular pigmentation (HP:0008002)1.96558623
126Hemoptysis (HP:0002105)1.96293180
127IgG deficiency (HP:0004315)1.96134220
128Pustule (HP:0200039)1.95911943
129Hemorrhage of the eye (HP:0011885)1.95469410
130Disinhibition (HP:0000734)1.95313639
131Abnormality of the peritoneum (HP:0002585)1.95277804
132Lymphoma (HP:0002665)1.94987041
133Abnormal delayed hypersensitivity skin test (HP:0002963)1.94320631
134Skin rash (HP:0000988)1.93719584
135Increased IgM level (HP:0003496)1.93303177
136Dysostosis multiplex (HP:0000943)1.92976579
137Polycythemia (HP:0001901)1.92483309
138Bronchiectasis (HP:0002110)1.91552470
139Basal ganglia calcification (HP:0002135)1.91163834
140Osteomyelitis (HP:0002754)1.90043619
141Cone-rod dystrophy (HP:0000548)1.88100167
142Gastrointestinal infarctions (HP:0005244)1.86547570
143Gastrointestinal stroma tumor (HP:0100723)1.85180514
144Upper motor neuron abnormality (HP:0002127)1.83657203
145Choroideremia (HP:0001139)1.83399558
146Peritonitis (HP:0002586)1.82637438
147Spontaneous hematomas (HP:0007420)1.82599786
148Cerebral aneurysm (HP:0004944)1.80380053
149Mitral stenosis (HP:0001718)1.79993310
150Amyloidosis (HP:0011034)1.78900117
151Photophobia (HP:0000613)1.78344464
152Attenuation of retinal blood vessels (HP:0007843)1.77437006

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TYK23.89370547
2ERN13.59828661
3TBK13.54068168
4FGFR43.18540882
5MAP3K142.97464931
6IKBKE2.96260516
7JAK12.74874130
8JAK32.63877806
9PRPF4B2.62044624
10KIT2.57203954
11TRIB32.45850368
12MAP4K12.40414166
13BLK2.13675462
14RIPK12.05492324
15TESK21.98867153
16EPHB11.91594303
17RIPK41.87998310
18FGFR31.79057583
19TAOK31.65904978
20IKBKB1.61394571
21MAP3K131.59764254
22MAP3K101.59661754
23IRAK41.59112848
24TESK11.55788780
25EPHA31.54942507
26ZAP701.54549479
27TAOK21.51388338
28GRK61.49317309
29PDK41.45995749
30PDK31.45995749
31TNK21.42665499
32KSR21.40692826
33SIK21.39611538
34TTN1.36938307
35GRK71.36863922
36PKN21.34992188
37CHUK1.32550908
38MAP3K111.31436552
39TGFBR21.27781941
40CSK1.24581110
41CAMK1D1.22162089
42PTK61.21828773
43CSF1R1.21391168
44ICK1.20812923
45SYK1.18264594
46JAK21.18134698
47SIK11.17747788
48HCK1.06040728
49PDK21.02683621
50IRAK31.00184422
51CAMK1G0.99708617
52PRKD30.95979878
53YES10.94789413
54BMPR20.92575207
55MAP2K30.91651608
56FLT30.91114446
57BTK0.90530983
58CLK10.86752707
59TXK0.84891891
60EEF2K0.84329905
61IRAK10.82169598
62RET0.81746749
63SMG10.78796213
64MATK0.77839064
65CDC42BPA0.76774647
66PTK2B0.76169698
67FES0.75109484
68RPS6KA40.74383046
69RAF10.73455806
70SIK30.72857637
71MAP3K50.72747199
72DYRK1B0.69391518
73LCK0.69315309
74KSR10.66430846
75PDK10.62466399
76DAPK20.61812428
77GRK10.59565311
78DYRK30.59343937
79TAOK10.59273785
80CDK120.56817769
81MAPK110.52245081
82NEK90.51429126
83FYN0.50611380
84MARK20.50160787
85STK380.49868120
86LYN0.47699593
87DMPK0.46107091
88STK100.45947542
89CAMKK10.45613830
90MAP3K30.45189346
91PRKAA20.44971639
92BMX0.44613470
93MAP4K20.44431889
94IRAK20.44223905
95MAP3K10.44189439
96ITK0.43510606
97EGFR0.43210506
98PDGFRA0.42483002
99PHKG10.42198569
100PHKG20.42198569
101PDGFRB0.41950934
102MAPKAPK20.41943248
103PRKD20.41675211
104STK30.41610654
105ARAF0.41080787
106PIM20.40697113
107MAPK70.40178881
108PDPK10.39237339
109MAP2K60.38357277
110PRKCH0.37629353
111BCKDK0.36540179
112PIM10.35716454
113PRKAA10.35448039
114NEK60.35079304
115MAP3K60.34905121
116LRRK20.34638870
117NLK0.33101745
118HIPK20.32632827
119ABL10.32456588
120NEK20.32390510
121MAP3K80.32191616
122SGK30.32067349
123MARK30.31396566
124MAP3K70.30714119
125PRKCQ0.30206427
126MAPK120.30133630
127MAPK150.30064139
128FGR0.29601034
129CDK60.28916658
130TEC0.28779384
131MOS0.27856171
132RPS6KA50.27294364
133CDK40.25076158
134SRPK10.25072530
135MAP2K40.22560101
136BRD40.22441246

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.81918624
2Staphylococcus aureus infection_Homo sapiens_hsa051502.66436413
3Leishmaniasis_Homo sapiens_hsa051402.61034122
4Toll-like receptor signaling pathway_Homo sapiens_hsa046202.38139577
5Osteoclast differentiation_Homo sapiens_hsa043802.22572303
6RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.13398006
7Measles_Homo sapiens_hsa051622.12923809
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.11945193
9Caffeine metabolism_Homo sapiens_hsa002322.07239564
10Influenza A_Homo sapiens_hsa051641.91852455
11Toxoplasmosis_Homo sapiens_hsa051451.81903697
12B cell receptor signaling pathway_Homo sapiens_hsa046621.76195838
13TNF signaling pathway_Homo sapiens_hsa046681.74701748
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.72284905
15Legionellosis_Homo sapiens_hsa051341.65525851
16Tuberculosis_Homo sapiens_hsa051521.64591376
17Pertussis_Homo sapiens_hsa051331.58044002
18Intestinal immune network for IgA production_Homo sapiens_hsa046721.52393520
19Antigen processing and presentation_Homo sapiens_hsa046121.49609824
20Herpes simplex infection_Homo sapiens_hsa051681.45444994
21Allograft rejection_Homo sapiens_hsa053301.41874135
22NOD-like receptor signaling pathway_Homo sapiens_hsa046211.40920473
23Adipocytokine signaling pathway_Homo sapiens_hsa049201.37817042
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.35649961
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.35242874
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.34339400
27Malaria_Homo sapiens_hsa051441.32906058
28Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.32682188
29Lysosome_Homo sapiens_hsa041421.30125353
30Hepatitis C_Homo sapiens_hsa051601.28475552
31Chemokine signaling pathway_Homo sapiens_hsa040621.25388608
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.25291333
33Primary immunodeficiency_Homo sapiens_hsa053401.19674212
34Apoptosis_Homo sapiens_hsa042101.19635579
35Graft-versus-host disease_Homo sapiens_hsa053321.16227286
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16195818
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.12699001
38Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.12471461
39Complement and coagulation cascades_Homo sapiens_hsa046101.12075918
40Viral myocarditis_Homo sapiens_hsa054161.11906261
41Insulin resistance_Homo sapiens_hsa049311.10790818
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.10348991
43Prolactin signaling pathway_Homo sapiens_hsa049171.09339327
44Salmonella infection_Homo sapiens_hsa051321.07628112
45Acute myeloid leukemia_Homo sapiens_hsa052211.06328003
46ABC transporters_Homo sapiens_hsa020101.04290384
47Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.03689653
48Shigellosis_Homo sapiens_hsa051311.03212467
49Hepatitis B_Homo sapiens_hsa051610.99644832
50Type II diabetes mellitus_Homo sapiens_hsa049300.97920750
51T cell receptor signaling pathway_Homo sapiens_hsa046600.95795695
52PPAR signaling pathway_Homo sapiens_hsa033200.94870386
53Carbohydrate digestion and absorption_Homo sapiens_hsa049730.93385310
54AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.92405868
55Chronic myeloid leukemia_Homo sapiens_hsa052200.90980916
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90840541
57Other glycan degradation_Homo sapiens_hsa005110.88240509
58African trypanosomiasis_Homo sapiens_hsa051430.81756130
59Neurotrophin signaling pathway_Homo sapiens_hsa047220.80967136
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.78475124
61Rheumatoid arthritis_Homo sapiens_hsa053230.77821632
62Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75324444
63VEGF signaling pathway_Homo sapiens_hsa043700.73391964
64Phagosome_Homo sapiens_hsa041450.72447648
65Pancreatic cancer_Homo sapiens_hsa052120.71425168
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.69232776
67Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69000186
68Arginine biosynthesis_Homo sapiens_hsa002200.68758837
69Asthma_Homo sapiens_hsa053100.68444306
70Amoebiasis_Homo sapiens_hsa051460.67968585
71Renal cell carcinoma_Homo sapiens_hsa052110.67521029
72Hematopoietic cell lineage_Homo sapiens_hsa046400.66981834
73Notch signaling pathway_Homo sapiens_hsa043300.66489455
74Leukocyte transendothelial migration_Homo sapiens_hsa046700.65047983
75HTLV-I infection_Homo sapiens_hsa051660.64173372
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62178815
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.59368309
78Fatty acid degradation_Homo sapiens_hsa000710.58661284
79HIF-1 signaling pathway_Homo sapiens_hsa040660.58216395
80Platelet activation_Homo sapiens_hsa046110.57809754
81Endometrial cancer_Homo sapiens_hsa052130.56723011
82Dorso-ventral axis formation_Homo sapiens_hsa043200.56394434
83Small cell lung cancer_Homo sapiens_hsa052220.56157109
84Systemic lupus erythematosus_Homo sapiens_hsa053220.54540566
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52393191
86Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.52212367
87Fructose and mannose metabolism_Homo sapiens_hsa000510.48661089
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48056309
89Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47636605
90Insulin signaling pathway_Homo sapiens_hsa049100.46966234
91Autoimmune thyroid disease_Homo sapiens_hsa053200.45924543
92Lysine degradation_Homo sapiens_hsa003100.45633960
93Type I diabetes mellitus_Homo sapiens_hsa049400.44279821
94Bladder cancer_Homo sapiens_hsa052190.42497847
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42398725
96SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41298841
97FoxO signaling pathway_Homo sapiens_hsa040680.39802745
98Endocytosis_Homo sapiens_hsa041440.39448572
99Prion diseases_Homo sapiens_hsa050200.39035182
100Glucagon signaling pathway_Homo sapiens_hsa049220.38929787
101Vibrio cholerae infection_Homo sapiens_hsa051100.38413409
102Fatty acid biosynthesis_Homo sapiens_hsa000610.37224467
103Pentose phosphate pathway_Homo sapiens_hsa000300.36769095
104Collecting duct acid secretion_Homo sapiens_hsa049660.36226726
105AMPK signaling pathway_Homo sapiens_hsa041520.35999281
106mTOR signaling pathway_Homo sapiens_hsa041500.35634019
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.35633604
108Central carbon metabolism in cancer_Homo sapiens_hsa052300.35175990
109Colorectal cancer_Homo sapiens_hsa052100.34588747
110Glycerolipid metabolism_Homo sapiens_hsa005610.34543709
111Inositol phosphate metabolism_Homo sapiens_hsa005620.34129276
112Regulation of autophagy_Homo sapiens_hsa041400.32801618
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.32102658
114Non-small cell lung cancer_Homo sapiens_hsa052230.31941287
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30173026
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29919598
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.29539834
118Fatty acid metabolism_Homo sapiens_hsa012120.28806220
119Choline metabolism in cancer_Homo sapiens_hsa052310.28324349
120Epstein-Barr virus infection_Homo sapiens_hsa051690.27926096
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27829549
122Viral carcinogenesis_Homo sapiens_hsa052030.27478258
123ErbB signaling pathway_Homo sapiens_hsa040120.24835703
124Prostate cancer_Homo sapiens_hsa052150.23678531
125Galactose metabolism_Homo sapiens_hsa000520.22611584

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