

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 9.47675487 |
| 2 | negative regulation of T cell apoptotic process (GO:0070233) | 5.93804843 |
| 3 | negative T cell selection (GO:0043383) | 5.76536390 |
| 4 | positive regulation of tolerance induction (GO:0002645) | 5.66538077 |
| 5 | positive T cell selection (GO:0043368) | 5.58037833 |
| 6 | regulation of T cell tolerance induction (GO:0002664) | 5.57514312 |
| 7 | T cell migration (GO:0072678) | 5.51522357 |
| 8 | pyrimidine nucleoside catabolic process (GO:0046135) | 5.39414071 |
| 9 | regulation of B cell differentiation (GO:0045577) | 5.34930756 |
| 10 | regulation of lymphocyte chemotaxis (GO:1901623) | 5.24732301 |
| 11 | negative regulation by host of viral transcription (GO:0043922) | 5.19970009 |
| 12 | eosinophil chemotaxis (GO:0048245) | 5.18656937 |
| 13 | positive regulation of B cell differentiation (GO:0045579) | 5.13822750 |
| 14 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.13352627 |
| 15 | monocyte chemotaxis (GO:0002548) | 5.10180263 |
| 16 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.81797623 |
| 17 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.77139507 |
| 18 | negative regulation of viral genome replication (GO:0045071) | 4.75949634 |
| 19 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.71001793 |
| 20 | eosinophil migration (GO:0072677) | 4.69182969 |
| 21 | regulation of tolerance induction (GO:0002643) | 4.59382162 |
| 22 | regulation of activation of Janus kinase activity (GO:0010533) | 4.58087551 |
| 23 | regulation of regulatory T cell differentiation (GO:0045589) | 4.48376281 |
| 24 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.44607012 |
| 25 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.40766635 |
| 26 | macrophage chemotaxis (GO:0048246) | 4.36102709 |
| 27 | regulation of T cell chemotaxis (GO:0010819) | 4.34200973 |
| 28 | positive regulation of T cell chemotaxis (GO:0010820) | 4.34200973 |
| 29 | cytolysis (GO:0019835) | 4.33919412 |
| 30 | proteasome assembly (GO:0043248) | 4.29967586 |
| 31 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.27468579 |
| 32 | T cell selection (GO:0045058) | 4.24902147 |
| 33 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.23841852 |
| 34 | thymic T cell selection (GO:0045061) | 4.20043443 |
| 35 | positive thymic T cell selection (GO:0045059) | 4.17851183 |
| 36 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.16316031 |
| 37 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.16316031 |
| 38 | lymphocyte chemotaxis (GO:0048247) | 4.15089438 |
| 39 | negative thymic T cell selection (GO:0045060) | 4.13891475 |
| 40 | regulation of T cell apoptotic process (GO:0070232) | 4.12017095 |
| 41 | cellular response to interleukin-15 (GO:0071350) | 4.11388532 |
| 42 | positive regulation of lymphocyte migration (GO:2000403) | 4.08943205 |
| 43 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.05513128 |
| 44 | T cell receptor signaling pathway (GO:0050852) | 4.01010107 |
| 45 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.99560326 |
| 46 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.97778515 |
| 47 | negative regulation of organelle assembly (GO:1902116) | 3.97214877 |
| 48 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.92126590 |
| 49 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.87787050 |
| 50 | cellular defense response (GO:0006968) | 3.81660190 |
| 51 | positive regulation of cell killing (GO:0031343) | 3.79533802 |
| 52 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.78920748 |
| 53 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.75558611 |
| 54 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.74572085 |
| 55 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.74326781 |
| 56 | regulation of gamma-delta T cell activation (GO:0046643) | 3.67790639 |
| 57 | positive regulation of macrophage differentiation (GO:0045651) | 3.63437396 |
| 58 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.62796207 |
| 59 | immunoglobulin mediated immune response (GO:0016064) | 3.60418015 |
| 60 | activated T cell proliferation (GO:0050798) | 3.59733298 |
| 61 | positive regulation of interleukin-4 production (GO:0032753) | 3.58607622 |
| 62 | regulation of cell killing (GO:0031341) | 3.54489891 |
| 63 | actin nucleation (GO:0045010) | 3.53156053 |
| 64 | regulation of lymphocyte migration (GO:2000401) | 3.51348978 |
| 65 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.50908657 |
| 66 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.46546023 |
| 67 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.46113101 |
| 68 | lymphocyte migration (GO:0072676) | 3.45598516 |
| 69 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.44843017 |
| 70 | negative regulation of cell killing (GO:0031342) | 3.43878020 |
| 71 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.43878020 |
| 72 | regulation of calcium-mediated signaling (GO:0050848) | 3.41907238 |
| 73 | negative regulation of B cell proliferation (GO:0030889) | 3.41597921 |
| 74 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.40999175 |
| 75 | negative regulation of viral transcription (GO:0032897) | 3.40095649 |
| 76 | regulation of mononuclear cell migration (GO:0071675) | 3.34098648 |
| 77 | negative regulation of viral process (GO:0048525) | 3.33073088 |
| 78 | response to interleukin-15 (GO:0070672) | 3.32577363 |
| 79 | regulation of macrophage chemotaxis (GO:0010758) | 3.32488233 |
| 80 | regulation of viral genome replication (GO:0045069) | 3.28527263 |
| 81 | interferon-gamma production (GO:0032609) | 3.19603952 |
| 82 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.18603651 |
| 83 | positive regulation of T cell apoptotic process (GO:0070234) | 3.17500168 |
| 84 | regulation of defense response to virus by virus (GO:0050690) | 3.16989644 |
| 85 | negative regulation of stress fiber assembly (GO:0051497) | 3.14581638 |
| 86 | T cell costimulation (GO:0031295) | 3.14410961 |
| 87 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.14288413 |
| 88 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 3.13089970 |
| 89 | regulation of chronic inflammatory response (GO:0002676) | 3.12852478 |
| 90 | B cell mediated immunity (GO:0019724) | 3.11418754 |
| 91 | modulation by host of symbiont transcription (GO:0052472) | 3.11312359 |
| 92 | modulation by host of viral transcription (GO:0043921) | 3.11312359 |
| 93 | lymphocyte costimulation (GO:0031294) | 3.10597555 |
| 94 | positive regulation of interleukin-2 production (GO:0032743) | 3.09216025 |
| 95 | granulocyte activation (GO:0036230) | 3.08539547 |
| 96 | cytidine deamination (GO:0009972) | 13.1510523 |
| 97 | cytidine metabolic process (GO:0046087) | 13.1510523 |
| 98 | cytidine catabolic process (GO:0006216) | 13.1510523 |
| 99 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 11.6713627 |
| 100 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 10.0563358 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 9.40128745 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.37090936 |
| 3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.36502456 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.28955761 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.20681434 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.68209499 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.51908010 |
| 8 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.13691918 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.09962494 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.07222082 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 3.01524392 |
| 12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.84032347 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.76767206 |
| 14 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.72991217 |
| 15 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.72878723 |
| 16 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.61011193 |
| 17 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.48186010 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.28066009 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.25264797 |
| 20 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.12887697 |
| 21 | MYB_26560356_Chip-Seq_TH1_Human | 2.12253598 |
| 22 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.10113802 |
| 23 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.99657395 |
| 24 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.99373512 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.92718278 |
| 26 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.90037087 |
| 27 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.79722522 |
| 28 | UTX_26944678_Chip-Seq_JUKART_Human | 1.71454192 |
| 29 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.71445962 |
| 30 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.65194859 |
| 31 | MAF_26560356_Chip-Seq_TH1_Human | 1.63482845 |
| 32 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.61149712 |
| 33 | GATA3_26560356_Chip-Seq_TH2_Human | 1.44853563 |
| 34 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.42628076 |
| 35 | MAF_26560356_Chip-Seq_TH2_Human | 1.41359534 |
| 36 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.39180148 |
| 37 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.37003875 |
| 38 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29051019 |
| 39 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.26497771 |
| 40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22906925 |
| 41 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.18322148 |
| 42 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.10948209 |
| 43 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07802726 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06950688 |
| 45 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06336775 |
| 46 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.04862839 |
| 47 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.04616222 |
| 48 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.03613604 |
| 49 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.03392774 |
| 50 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.03069485 |
| 51 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.01984008 |
| 52 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.00488268 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97626423 |
| 54 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.97345674 |
| 55 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.93714556 |
| 56 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.93240942 |
| 57 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.92947805 |
| 58 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.92665112 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.92320233 |
| 60 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.90041733 |
| 61 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.86931207 |
| 62 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.84910870 |
| 63 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.84759369 |
| 64 | GATA3_26560356_Chip-Seq_TH1_Human | 0.84550657 |
| 65 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.83701810 |
| 66 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.83594737 |
| 67 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.81953386 |
| 68 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.81058047 |
| 69 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.79595312 |
| 70 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.79378654 |
| 71 | P300_27268052_Chip-Seq_Bcells_Human | 0.78482619 |
| 72 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.78414996 |
| 73 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.77348267 |
| 74 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.76126720 |
| 75 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.74067243 |
| 76 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.73963033 |
| 77 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.73343322 |
| 78 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.72303284 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.72292691 |
| 80 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.72270504 |
| 81 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.71052568 |
| 82 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.70966326 |
| 83 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.70666450 |
| 84 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.70203306 |
| 85 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.70074820 |
| 86 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.69034976 |
| 87 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.68879658 |
| 88 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.68836538 |
| 89 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.68738451 |
| 90 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.67901725 |
| 91 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.67104914 |
| 92 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.67030589 |
| 93 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.66608628 |
| 94 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.66210000 |
| 95 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.66108882 |
| 96 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.65623303 |
| 97 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.64376303 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.64319675 |
| 99 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.64319675 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.64198814 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.66633934 |
| 2 | MP0003763_abnormal_thymus_physiology | 5.78656487 |
| 3 | MP0009333_abnormal_splenocyte_physiolog | 3.66735417 |
| 4 | MP0006082_CNS_inflammation | 3.51687979 |
| 5 | MP0001873_stomach_inflammation | 3.32726563 |
| 6 | MP0009785_altered_susceptibility_to | 3.27067102 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.02801723 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.88715251 |
| 9 | MP0002723_abnormal_immune_serum | 2.61133562 |
| 10 | MP0001800_abnormal_humoral_immune | 2.61123544 |
| 11 | MP0002405_respiratory_system_inflammati | 2.60829280 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.60739460 |
| 13 | MP0001790_abnormal_immune_system | 2.57146564 |
| 14 | MP0005387_immune_system_phenotype | 2.57146564 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 2.52239695 |
| 16 | MP0003045_fibrosis | 2.48947253 |
| 17 | MP0001819_abnormal_immune_cell | 2.47725533 |
| 18 | MP0000703_abnormal_thymus_morphology | 2.41795943 |
| 19 | MP0003866_abnormal_defecation | 2.41578776 |
| 20 | MP0003786_premature_aging | 2.40933251 |
| 21 | MP0005025_abnormal_response_to | 2.38841511 |
| 22 | MP0002398_abnormal_bone_marrow | 2.15538397 |
| 23 | MP0000716_abnormal_immune_system | 2.13385452 |
| 24 | MP0003448_altered_tumor_morphology | 2.11543527 |
| 25 | MP0001188_hyperpigmentation | 2.00813297 |
| 26 | MP0002452_abnormal_antigen_presenting | 1.87012476 |
| 27 | MP0002722_abnormal_immune_system | 1.80529058 |
| 28 | MP0002277_abnormal_respiratory_mucosa | 1.77164766 |
| 29 | MP0004947_skin_inflammation | 1.75462772 |
| 30 | MP0000689_abnormal_spleen_morphology | 1.71175993 |
| 31 | MP0010155_abnormal_intestine_physiology | 1.70407441 |
| 32 | MP0002166_altered_tumor_susceptibility | 1.69432890 |
| 33 | MP0000685_abnormal_immune_system | 1.68999451 |
| 34 | MP0001905_abnormal_dopamine_level | 1.63455250 |
| 35 | MP0005464_abnormal_platelet_physiology | 1.62862516 |
| 36 | MP0001919_abnormal_reproductive_system | 1.58291828 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.54275323 |
| 38 | MP0002429_abnormal_blood_cell | 1.54014641 |
| 39 | MP0002102_abnormal_ear_morphology | 1.44285272 |
| 40 | MP0002933_joint_inflammation | 1.42614518 |
| 41 | MP0002419_abnormal_innate_immunity | 1.41959079 |
| 42 | MP0009763_increased_sensitivity_to | 1.40104874 |
| 43 | MP0008007_abnormal_cellular_replicative | 1.36417705 |
| 44 | MP0001984_abnormal_olfaction | 1.29235159 |
| 45 | MP0000569_abnormal_digit_pigmentation | 1.27162859 |
| 46 | MP0002006_tumorigenesis | 1.23489886 |
| 47 | MP0001853_heart_inflammation | 1.16077690 |
| 48 | MP0004381_abnormal_hair_follicle | 1.14863217 |
| 49 | MP0005377_hearing/vestibular/ear_phenot | 1.01036119 |
| 50 | MP0003878_abnormal_ear_physiology | 1.01036119 |
| 51 | MP0008469_abnormal_protein_level | 0.99748866 |
| 52 | MP0008873_increased_physiological_sensi | 0.98852100 |
| 53 | MP0006072_abnormal_retinal_apoptosis | 0.98114664 |
| 54 | MP0000858_altered_metastatic_potential | 0.96016906 |
| 55 | MP0000920_abnormal_myelination | 0.94310580 |
| 56 | MP0003724_increased_susceptibility_to | 0.90300270 |
| 57 | MP0003567_abnormal_fetal_cardiomyocyte | 0.88779462 |
| 58 | MP0002019_abnormal_tumor_incidence | 0.86975991 |
| 59 | MP0010307_abnormal_tumor_latency | 0.85541212 |
| 60 | MP0009643_abnormal_urine_homeostasis | 0.83320614 |
| 61 | MP0004742_abnormal_vestibular_system | 0.83236798 |
| 62 | MP0002138_abnormal_hepatobiliary_system | 0.83236189 |
| 63 | MP0005389_reproductive_system_phenotype | 0.82082626 |
| 64 | MP0002653_abnormal_ependyma_morphology | 0.81557423 |
| 65 | MP0003436_decreased_susceptibility_to | 0.81090509 |
| 66 | MP0001243_abnormal_dermal_layer | 0.80125875 |
| 67 | MP0005075_abnormal_melanosome_morpholog | 0.78160167 |
| 68 | MP0002136_abnormal_kidney_physiology | 0.77617162 |
| 69 | MP0003646_muscle_fatigue | 0.76824884 |
| 70 | MP0009765_abnormal_xenobiotic_induced | 0.76409073 |
| 71 | MP0001542_abnormal_bone_strength | 0.75218281 |
| 72 | MP0002998_abnormal_bone_remodeling | 0.74707280 |
| 73 | MP0004142_abnormal_muscle_tone | 0.74446496 |
| 74 | MP0004145_abnormal_muscle_electrophysio | 0.74181316 |
| 75 | MP0003183_abnormal_peptide_metabolism | 0.71563696 |
| 76 | MP0005410_abnormal_fertilization | 0.70822357 |
| 77 | MP0008995_early_reproductive_senescence | 0.67774003 |
| 78 | MP0005645_abnormal_hypothalamus_physiol | 0.66663110 |
| 79 | MP0002168_other_aberrant_phenotype | 0.66593123 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.65927921 |
| 81 | MP0005166_decreased_susceptibility_to | 0.64287693 |
| 82 | MP0005253_abnormal_eye_physiology | 0.62745502 |
| 83 | MP0005409_darkened_coat_color | 0.60129789 |
| 84 | MP0003011_delayed_dark_adaptation | 0.59167344 |
| 85 | MP0002877_abnormal_melanocyte_morpholog | 0.58920386 |
| 86 | MP0000647_abnormal_sebaceous_gland | 0.57666640 |
| 87 | MP0001765_abnormal_ion_homeostasis | 0.56803890 |
| 88 | MP0000639_abnormal_adrenal_gland | 0.56226427 |
| 89 | MP0003795_abnormal_bone_structure | 0.54872458 |
| 90 | MP0002638_abnormal_pupillary_reflex | 0.51357039 |
| 91 | MP0002909_abnormal_adrenal_gland | 0.50450536 |
| 92 | MP0002163_abnormal_gland_morphology | 0.48402314 |
| 93 | MP0001502_abnormal_circadian_rhythm | 0.46018637 |
| 94 | MP0002132_abnormal_respiratory_system | 0.45744223 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.42612106 |
| 96 | MP0001663_abnormal_digestive_system | 0.41560311 |
| 97 | MP0001968_abnormal_touch/_nociception | 0.40911545 |
| 98 | MP0002090_abnormal_vision | 0.40071995 |
| 99 | MP0001119_abnormal_female_reproductive | 0.39974445 |
| 100 | MP0001191_abnormal_skin_condition | 0.38486340 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 9.78620780 |
| 2 | T lymphocytopenia (HP:0005403) | 8.59414029 |
| 3 | Abnormality of T cell number (HP:0011839) | 7.64846552 |
| 4 | IgG deficiency (HP:0004315) | 4.89902400 |
| 5 | Hypoplasia of the thymus (HP:0000778) | 4.85826412 |
| 6 | IgM deficiency (HP:0002850) | 4.72700071 |
| 7 | Autoimmune hemolytic anemia (HP:0001890) | 4.66503473 |
| 8 | Abnormality of T cells (HP:0002843) | 4.62602505 |
| 9 | Cutaneous melanoma (HP:0012056) | 4.25319881 |
| 10 | Severe combined immunodeficiency (HP:0004430) | 4.22502775 |
| 11 | Abnormality of macrophages (HP:0004311) | 4.20909155 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.17820210 |
| 13 | Hypoproteinemia (HP:0003075) | 4.14952963 |
| 14 | Abnormality of eosinophils (HP:0001879) | 4.11426969 |
| 15 | Thyroiditis (HP:0100646) | 3.64763722 |
| 16 | Combined immunodeficiency (HP:0005387) | 3.53641249 |
| 17 | Rib fusion (HP:0000902) | 3.51122177 |
| 18 | Stomatitis (HP:0010280) | 3.49549427 |
| 19 | Eosinophilia (HP:0001880) | 3.43901295 |
| 20 | Lymphopenia (HP:0001888) | 3.35768566 |
| 21 | Recurrent bronchitis (HP:0002837) | 3.25549357 |
| 22 | Leukocytosis (HP:0001974) | 3.13567472 |
| 23 | Pancytopenia (HP:0001876) | 3.13314608 |
| 24 | Recurrent cutaneous fungal infections (HP:0011370) | 3.09127390 |
| 25 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.09127390 |
| 26 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.06068159 |
| 27 | Amyotrophic lateral sclerosis (HP:0007354) | 3.05893958 |
| 28 | Anomalous pulmonary venous return (HP:0010772) | 3.02885248 |
| 29 | Chronic diarrhea (HP:0002028) | 3.01698242 |
| 30 | Abnormality of the prostate (HP:0008775) | 3.00365117 |
| 31 | Joint swelling (HP:0001386) | 2.92566251 |
| 32 | Hemiplegia (HP:0002301) | 2.89513518 |
| 33 | Menstrual irregularities (HP:0000858) | 2.86219644 |
| 34 | Increased IgM level (HP:0003496) | 2.83081683 |
| 35 | Lymphoma (HP:0002665) | 2.82672272 |
| 36 | Granulocytopenia (HP:0001913) | 2.80683323 |
| 37 | Encephalitis (HP:0002383) | 2.78028952 |
| 38 | Abnormality of the pulmonary veins (HP:0011718) | 2.68445143 |
| 39 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.61909564 |
| 40 | Recurrent viral infections (HP:0004429) | 2.60229644 |
| 41 | Malignant hyperthermia (HP:0002047) | 2.59201340 |
| 42 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.58824716 |
| 43 | Gastrointestinal infarctions (HP:0005244) | 2.54273479 |
| 44 | Obstructive lung disease (HP:0006536) | 2.44683926 |
| 45 | Chronic obstructive pulmonary disease (HP:0006510) | 2.44683926 |
| 46 | Vasculitis (HP:0002633) | 2.42291289 |
| 47 | Bronchitis (HP:0012387) | 2.42281781 |
| 48 | Abnormal drinking behavior (HP:0030082) | 2.40793504 |
| 49 | Polydipsia (HP:0001959) | 2.40793504 |
| 50 | Purpura (HP:0000979) | 2.32109113 |
| 51 | Agammaglobulinemia (HP:0004432) | 2.31005159 |
| 52 | Meningitis (HP:0001287) | 2.30978119 |
| 53 | Abnormal albumin level (HP:0012116) | 2.30366659 |
| 54 | Hypoalbuminemia (HP:0003073) | 2.30366659 |
| 55 | Confusion (HP:0001289) | 2.28227906 |
| 56 | Recurrent bacterial skin infections (HP:0005406) | 2.26913562 |
| 57 | Recurrent skin infections (HP:0001581) | 2.26328685 |
| 58 | Increased cerebral lipofuscin (HP:0011813) | 2.24986812 |
| 59 | Chest pain (HP:0100749) | 2.24070670 |
| 60 | Ureteral stenosis (HP:0000071) | 2.17094244 |
| 61 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.16525954 |
| 62 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.13701722 |
| 63 | Polyuria (HP:0000103) | 2.10342091 |
| 64 | Acute hepatic failure (HP:0006554) | 2.10194553 |
| 65 | Fused cervical vertebrae (HP:0002949) | 2.08874433 |
| 66 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.07764395 |
| 67 | Ureteral obstruction (HP:0006000) | 2.07009071 |
| 68 | Generalized aminoaciduria (HP:0002909) | 2.02538314 |
| 69 | Abnormality of binocular vision (HP:0011514) | 2.00862761 |
| 70 | Diplopia (HP:0000651) | 2.00862761 |
| 71 | Oligomenorrhea (HP:0000876) | 2.00659056 |
| 72 | Autoimmune thrombocytopenia (HP:0001973) | 1.98913345 |
| 73 | Amniotic constriction ring (HP:0009775) | 1.93496957 |
| 74 | Abnormality of placental membranes (HP:0011409) | 1.93496957 |
| 75 | Recurrent fungal infections (HP:0002841) | 1.92744807 |
| 76 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.91710435 |
| 77 | Spontaneous hematomas (HP:0007420) | 1.91016967 |
| 78 | Alveolar cell carcinoma (HP:0006519) | 1.90832992 |
| 79 | Recurrent otitis media (HP:0000403) | 1.89523358 |
| 80 | Failure to thrive in infancy (HP:0001531) | 1.88549164 |
| 81 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.85093462 |
| 82 | Hyponatremia (HP:0002902) | 1.84199915 |
| 83 | Glucose intolerance (HP:0000833) | 1.84144390 |
| 84 | Periodontitis (HP:0000704) | 1.83945361 |
| 85 | Gangrene (HP:0100758) | 1.83664027 |
| 86 | Methylmalonic aciduria (HP:0012120) | 1.83387987 |
| 87 | Type I diabetes mellitus (HP:0100651) | 1.83333814 |
| 88 | Respiratory distress (HP:0002098) | 1.81456597 |
| 89 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.81026236 |
| 90 | Abnormality of alanine metabolism (HP:0010916) | 1.81026236 |
| 91 | Hyperalaninemia (HP:0003348) | 1.81026236 |
| 92 | Aplasia of the musculature (HP:0100854) | 1.80312167 |
| 93 | Pustule (HP:0200039) | 1.78997199 |
| 94 | Popliteal pterygium (HP:0009756) | 1.78729324 |
| 95 | Hypergammaglobulinemia (HP:0010702) | 1.78554712 |
| 96 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.77538422 |
| 97 | Abnormal urine output (HP:0012590) | 1.76076388 |
| 98 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.74593339 |
| 99 | Recurrent abscess formation (HP:0002722) | 1.74268711 |
| 100 | Hypokalemia (HP:0002900) | 1.73865339 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.12905204 |
| 2 | KDR | 5.78132327 |
| 3 | MAP4K1 | 5.11800347 |
| 4 | ITK | 3.53022666 |
| 5 | TESK2 | 3.32454625 |
| 6 | CSK | 2.80697908 |
| 7 | SCYL2 | 2.77028636 |
| 8 | BUB1 | 2.63967663 |
| 9 | FES | 2.63211843 |
| 10 | TNK2 | 2.60673594 |
| 11 | TYRO3 | 2.49555555 |
| 12 | TAOK3 | 2.37710939 |
| 13 | ZAP70 | 2.24951976 |
| 14 | MAPKAPK3 | 2.19719150 |
| 15 | SYK | 1.77690339 |
| 16 | MAP2K7 | 1.73872901 |
| 17 | PRKCQ | 1.73563314 |
| 18 | MAP3K11 | 1.71939447 |
| 19 | TEC | 1.60879772 |
| 20 | BTK | 1.58159457 |
| 21 | LCK | 1.57982418 |
| 22 | MST4 | 1.52187359 |
| 23 | TESK1 | 1.51954828 |
| 24 | GRK6 | 1.37435770 |
| 25 | STK38L | 1.35609272 |
| 26 | IKBKE | 1.31502635 |
| 27 | FGFR1 | 1.30683393 |
| 28 | PDGFRB | 1.29321365 |
| 29 | ADRBK2 | 1.21611733 |
| 30 | STK38 | 1.09329100 |
| 31 | JAK3 | 1.07243374 |
| 32 | BCKDK | 1.04982951 |
| 33 | IKBKB | 1.03833620 |
| 34 | TBK1 | 1.02452176 |
| 35 | RIPK4 | 0.99533300 |
| 36 | LIMK1 | 0.95060244 |
| 37 | LYN | 0.86743128 |
| 38 | CSF1R | 0.86319727 |
| 39 | ACVR1B | 0.86136882 |
| 40 | AKT3 | 0.82396057 |
| 41 | HCK | 0.80507001 |
| 42 | PIK3CA | 0.75420195 |
| 43 | FYN | 0.72635446 |
| 44 | FGFR2 | 0.71328323 |
| 45 | FRK | 0.67136271 |
| 46 | INSR | 0.66971257 |
| 47 | NEK6 | 0.60576729 |
| 48 | ATR | 0.59401847 |
| 49 | AURKA | 0.56449112 |
| 50 | PIK3CG | 0.55602251 |
| 51 | CAMKK2 | 0.52557808 |
| 52 | STK24 | 0.49252160 |
| 53 | FGR | 0.47920722 |
| 54 | IGF1R | 0.47851178 |
| 55 | VRK1 | 0.46581175 |
| 56 | ROCK1 | 0.46371278 |
| 57 | PLK2 | 0.44881926 |
| 58 | OBSCN | 0.43994728 |
| 59 | MAPK7 | 0.40409006 |
| 60 | VRK2 | 0.40387377 |
| 61 | RPS6KB1 | 0.39002362 |
| 62 | MAPK12 | 0.38225140 |
| 63 | ERBB3 | 0.37143189 |
| 64 | PIM1 | 0.36022592 |
| 65 | INSRR | 0.35920769 |
| 66 | MAP3K14 | 0.34627650 |
| 67 | CHUK | 0.34475453 |
| 68 | PRKCA | 0.33668495 |
| 69 | DAPK1 | 0.32164962 |
| 70 | CAMK2A | 0.31819474 |
| 71 | MAPK11 | 0.31418433 |
| 72 | WNK4 | 0.31141383 |
| 73 | BMPR2 | 0.30703146 |
| 74 | PRKCI | 0.30332349 |
| 75 | ADRBK1 | 0.29880871 |
| 76 | PRKCH | 0.29334454 |
| 77 | MAPK3 | 0.25324417 |
| 78 | TYK2 | 0.24069445 |
| 79 | PASK | 0.23961009 |
| 80 | GRK7 | 0.23948471 |
| 81 | PAK1 | 0.23698692 |
| 82 | MARK3 | 0.23662770 |
| 83 | PRKACA | 0.23016406 |
| 84 | MAPK9 | 0.22872678 |
| 85 | JAK1 | 0.21961639 |
| 86 | MAP3K5 | 0.21953514 |
| 87 | GRK1 | 0.21167196 |
| 88 | KIT | 0.21061515 |
| 89 | MUSK | 0.20944508 |
| 90 | SRC | 0.20263754 |
| 91 | PDK1 | 0.18546950 |
| 92 | BCR | 0.18291655 |
| 93 | NTRK2 | 0.18047110 |
| 94 | PRKCB | 0.17830833 |
| 95 | MAP4K2 | 0.17338835 |
| 96 | MAP2K6 | 0.16706019 |
| 97 | STK10 | 0.16699827 |
| 98 | MAPKAPK2 | 0.16698262 |
| 99 | PRKACG | 0.16589003 |
| 100 | CSNK1A1 | 0.16551208 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.82029120 |
| 2 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 4.04933171 |
| 3 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.98353176 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.85766246 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.13559972 |
| 6 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.91915979 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.85166342 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.59916746 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.52351774 |
| 10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.40600474 |
| 11 | Measles_Homo sapiens_hsa05162 | 2.30325812 |
| 12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.24413608 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 2.24330817 |
| 14 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 2.06479069 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.05297132 |
| 16 | Salmonella infection_Homo sapiens_hsa05132 | 2.02064018 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.96243065 |
| 18 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.89483844 |
| 19 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.75302545 |
| 20 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.69545692 |
| 21 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.32832640 |
| 22 | Malaria_Homo sapiens_hsa05144 | 1.26035608 |
| 23 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.25497037 |
| 24 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.24024436 |
| 25 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.20702800 |
| 26 | Shigellosis_Homo sapiens_hsa05131 | 1.16756751 |
| 27 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.12032211 |
| 28 | Viral myocarditis_Homo sapiens_hsa05416 | 1.09578122 |
| 29 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.07949609 |
| 30 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.06317486 |
| 31 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.99011821 |
| 32 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.96930910 |
| 33 | Parkinsons disease_Homo sapiens_hsa05012 | 0.91761465 |
| 34 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.89508107 |
| 35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.88066625 |
| 36 | Prion diseases_Homo sapiens_hsa05020 | 0.80370428 |
| 37 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.79569730 |
| 38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.78935470 |
| 39 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.77961692 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72581995 |
| 41 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71611002 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71485162 |
| 43 | Leishmaniasis_Homo sapiens_hsa05140 | 0.69014247 |
| 44 | Alzheimers disease_Homo sapiens_hsa05010 | 0.64350025 |
| 45 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.62860337 |
| 46 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.61603620 |
| 47 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.61111311 |
| 48 | Apoptosis_Homo sapiens_hsa04210 | 0.60439633 |
| 49 | Basal transcription factors_Homo sapiens_hsa03022 | 0.58734279 |
| 50 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.57753663 |
| 51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.57740815 |
| 52 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56814884 |
| 53 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.56687180 |
| 54 | Platelet activation_Homo sapiens_hsa04611 | 0.56570746 |
| 55 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.54417202 |
| 56 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.53354501 |
| 57 | RNA polymerase_Homo sapiens_hsa03020 | 0.53153403 |
| 58 | Protein export_Homo sapiens_hsa03060 | 0.52657498 |
| 59 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48243028 |
| 60 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.48072603 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.47251147 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.46791097 |
| 63 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.46719949 |
| 64 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.44248210 |
| 65 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.43469426 |
| 66 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.40371837 |
| 67 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.38032704 |
| 68 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.35981608 |
| 69 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.34831351 |
| 70 | HTLV-I infection_Homo sapiens_hsa05166 | 0.34748520 |
| 71 | Homologous recombination_Homo sapiens_hsa03440 | 0.33904597 |
| 72 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.32976167 |
| 73 | Pertussis_Homo sapiens_hsa05133 | 0.32937407 |
| 74 | Alcoholism_Homo sapiens_hsa05034 | 0.32807619 |
| 75 | Legionellosis_Homo sapiens_hsa05134 | 0.29607857 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.27362911 |
| 77 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.27362610 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26638579 |
| 79 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.26558755 |
| 80 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.26378373 |
| 81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.25706381 |
| 82 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.25095288 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24921659 |
| 84 | Influenza A_Homo sapiens_hsa05164 | 0.24513685 |
| 85 | Huntingtons disease_Homo sapiens_hsa05016 | 0.23564438 |
| 86 | Asthma_Homo sapiens_hsa05310 | 0.20460998 |
| 87 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.19718352 |
| 88 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.17527784 |
| 89 | Endocytosis_Homo sapiens_hsa04144 | 0.17286950 |
| 90 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.17110097 |
| 91 | Lysosome_Homo sapiens_hsa04142 | 0.17017340 |
| 92 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.15397474 |
| 93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.14989278 |
| 94 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.11970227 |
| 95 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.10837565 |
| 96 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.10201794 |
| 97 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.10032421 |
| 98 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.09812588 |
| 99 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.08927253 |
| 100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.07752812 |

