

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive T cell selection (GO:0043368) | 7.25445273 |
| 2 | positive regulation of fatty acid oxidation (GO:0046321) | 7.01220997 |
| 3 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 6.89307650 |
| 4 | positive thymic T cell selection (GO:0045059) | 6.79138413 |
| 5 | positive regulation of tolerance induction (GO:0002645) | 6.36644460 |
| 6 | actin nucleation (GO:0045010) | 6.24358926 |
| 7 | regulation of fatty acid beta-oxidation (GO:0031998) | 6.17270127 |
| 8 | negative T cell selection (GO:0043383) | 5.87098877 |
| 9 | regulation of T cell tolerance induction (GO:0002664) | 5.82061826 |
| 10 | cytidine deamination (GO:0009972) | 5.57509618 |
| 11 | cytidine metabolic process (GO:0046087) | 5.57509618 |
| 12 | cytidine catabolic process (GO:0006216) | 5.57509618 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.44013457 |
| 14 | positive regulation of natural killer cell differentiation (GO:0032825) | 5.43277978 |
| 15 | regulation of memory T cell differentiation (GO:0043380) | 5.26307143 |
| 16 | regulation of tolerance induction (GO:0002643) | 5.19990480 |
| 17 | thymic T cell selection (GO:0045061) | 5.18729818 |
| 18 | negative thymic T cell selection (GO:0045060) | 5.05438600 |
| 19 | protein neddylation (GO:0045116) | 5.04580370 |
| 20 | T cell selection (GO:0045058) | 4.88893325 |
| 21 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.88376218 |
| 22 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.76053654 |
| 23 | regulation of activation of Janus kinase activity (GO:0010533) | 4.46480301 |
| 24 | positive regulation of lipid catabolic process (GO:0050996) | 4.44399304 |
| 25 | regulation of ruffle assembly (GO:1900027) | 4.42559925 |
| 26 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.39285056 |
| 27 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.37346721 |
| 28 | positive regulation of interleukin-4 production (GO:0032753) | 4.32842445 |
| 29 | mucosal-associated lymphoid tissue development (GO:0048537) | 4.31819476 |
| 30 | Peyers patch development (GO:0048541) | 4.31819476 |
| 31 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.30281159 |
| 32 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.30096990 |
| 33 | respiratory burst (GO:0045730) | 4.26307644 |
| 34 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.21284272 |
| 35 | negative regulation of stress fiber assembly (GO:0051497) | 4.03840142 |
| 36 | cytolysis (GO:0019835) | 4.03650199 |
| 37 | signal complex assembly (GO:0007172) | 4.00140931 |
| 38 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.98548591 |
| 39 | negative regulation of viral genome replication (GO:0045071) | 3.97801957 |
| 40 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.90779483 |
| 41 | regulation of natural killer cell differentiation (GO:0032823) | 3.87001101 |
| 42 | negative regulation of oxidoreductase activity (GO:0051354) | 3.81041574 |
| 43 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.78004495 |
| 44 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.78004495 |
| 45 | positive regulation of cell killing (GO:0031343) | 3.71314328 |
| 46 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.68118345 |
| 47 | positive regulation of B cell differentiation (GO:0045579) | 3.66184476 |
| 48 | sequestering of actin monomers (GO:0042989) | 3.63644586 |
| 49 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.58459377 |
| 50 | negative regulation of actin filament bundle assembly (GO:0032232) | 3.58434269 |
| 51 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.56911359 |
| 52 | regulation of autophagic vacuole assembly (GO:2000785) | 3.51427165 |
| 53 | negative regulation of T cell apoptotic process (GO:0070233) | 3.50644746 |
| 54 | dopamine transport (GO:0015872) | 3.48123985 |
| 55 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.41942751 |
| 56 | type I interferon signaling pathway (GO:0060337) | 3.38841912 |
| 57 | cellular response to type I interferon (GO:0071357) | 3.38841912 |
| 58 | T cell migration (GO:0072678) | 3.38723151 |
| 59 | positive regulation of natural killer cell activation (GO:0032816) | 3.38513926 |
| 60 | response to type I interferon (GO:0034340) | 3.36023252 |
| 61 | T cell mediated immunity (GO:0002456) | 3.33811766 |
| 62 | regulation of viral genome replication (GO:0045069) | 3.33566423 |
| 63 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.33291362 |
| 64 | positive regulation of T cell mediated immunity (GO:0002711) | 3.32834818 |
| 65 | regulation of B cell differentiation (GO:0045577) | 3.31234290 |
| 66 | regulation of cell killing (GO:0031341) | 3.29154696 |
| 67 | positive regulation of fatty acid metabolic process (GO:0045923) | 3.27819157 |
| 68 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.22756398 |
| 69 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.18317281 |
| 70 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.17317744 |
| 71 | negative regulation of cell killing (GO:0031342) | 3.17317744 |
| 72 | regulation of fatty acid oxidation (GO:0046320) | 3.14776981 |
| 73 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.13897189 |
| 74 | regulation of vacuole organization (GO:0044088) | 3.13177723 |
| 75 | ATP synthesis coupled proton transport (GO:0015986) | 3.12759774 |
| 76 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.12759774 |
| 77 | negative regulation by host of viral transcription (GO:0043922) | 3.12430594 |
| 78 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.10475712 |
| 79 | negative regulation of monooxygenase activity (GO:0032769) | 3.09885741 |
| 80 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.04555976 |
| 81 | interferon-gamma production (GO:0032609) | 3.04512127 |
| 82 | T cell receptor signaling pathway (GO:0050852) | 3.03418758 |
| 83 | response to interferon-beta (GO:0035456) | 3.03173792 |
| 84 | regulation of interleukin-13 production (GO:0032656) | 3.03050594 |
| 85 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.02327077 |
| 86 | regulation of interleukin-4 production (GO:0032673) | 3.01067975 |
| 87 | cellular ketone body metabolic process (GO:0046950) | 2.97335188 |
| 88 | cellular response to reactive nitrogen species (GO:1902170) | 2.96090656 |
| 89 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2.94374151 |
| 90 | regulation of calcium-mediated signaling (GO:0050848) | 2.87530128 |
| 91 | centrosome localization (GO:0051642) | 2.86222314 |
| 92 | metallo-sulfur cluster assembly (GO:0031163) | 2.84418071 |
| 93 | iron-sulfur cluster assembly (GO:0016226) | 2.84418071 |
| 94 | positive regulation of actin filament polymerization (GO:0030838) | 2.82570455 |
| 95 | cellular response to interleukin-15 (GO:0071350) | 2.82073355 |
| 96 | T cell costimulation (GO:0031295) | 2.79734186 |
| 97 | response to interleukin-15 (GO:0070672) | 2.78357108 |
| 98 | lymphocyte costimulation (GO:0031294) | 2.76756128 |
| 99 | positive regulation of interleukin-17 production (GO:0032740) | 2.76574600 |
| 100 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 10.5223374 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 6.38810368 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.96028883 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.89423374 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.68483156 |
| 5 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 4.61739922 |
| 6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.63179522 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.21719718 |
| 8 | MYB_26560356_Chip-Seq_TH2_Human | 3.17229654 |
| 9 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.06260027 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.89538526 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.88629677 |
| 12 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.83449303 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.83435915 |
| 14 | MYB_26560356_Chip-Seq_TH1_Human | 2.50116907 |
| 15 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.45345299 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.42131376 |
| 17 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.39332074 |
| 18 | HTT_18923047_ChIP-ChIP_STHdh_Human | 2.29714900 |
| 19 | GATA3_26560356_Chip-Seq_TH2_Human | 2.19097876 |
| 20 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.16589397 |
| 21 | UTX_26944678_Chip-Seq_JUKART_Human | 2.16268705 |
| 22 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.14491965 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.02587012 |
| 24 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.96680627 |
| 25 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.94271827 |
| 26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.72402944 |
| 27 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.71058325 |
| 28 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.70735241 |
| 29 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.62785458 |
| 30 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.57483935 |
| 31 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.55037666 |
| 32 | VDR_22108803_ChIP-Seq_LS180_Human | 1.53459828 |
| 33 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.49659239 |
| 34 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.47323567 |
| 35 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.45531034 |
| 36 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45201453 |
| 37 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.44504573 |
| 38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.40052854 |
| 39 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.39990285 |
| 40 | MAF_26560356_Chip-Seq_TH1_Human | 1.37190218 |
| 41 | RXR_22108803_ChIP-Seq_LS180_Human | 1.32738997 |
| 42 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.29347110 |
| 43 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.23488015 |
| 44 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.21519487 |
| 45 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.20563747 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.17328230 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.16641193 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.15462575 |
| 49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14610688 |
| 50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14610688 |
| 51 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.12496496 |
| 52 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.11430804 |
| 53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.09796596 |
| 54 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.07796036 |
| 55 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.04360838 |
| 56 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04267865 |
| 57 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02884153 |
| 58 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.01145573 |
| 59 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.01145573 |
| 60 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99324307 |
| 61 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.98424225 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.98253459 |
| 63 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.98253459 |
| 64 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.98038540 |
| 65 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.96446122 |
| 66 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96374235 |
| 67 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.96207635 |
| 68 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.95142836 |
| 69 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94635017 |
| 70 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.92578298 |
| 71 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90965198 |
| 72 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.90936186 |
| 73 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90918239 |
| 74 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89840595 |
| 75 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88540889 |
| 76 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.88444916 |
| 77 | SPI1_23127762_ChIP-Seq_K562_Human | 0.86901441 |
| 78 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86831735 |
| 79 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86339954 |
| 80 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.86246203 |
| 81 | NCOR_22424771_ChIP-Seq_293T_Human | 0.85181661 |
| 82 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.85085044 |
| 83 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.84898239 |
| 84 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.84146112 |
| 85 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.83459279 |
| 86 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.81508522 |
| 87 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.78860634 |
| 88 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.78218578 |
| 89 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.78160046 |
| 90 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.77897048 |
| 91 | MAF_26560356_Chip-Seq_TH2_Human | 0.77567288 |
| 92 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.77440810 |
| 93 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.77242563 |
| 94 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.76882157 |
| 95 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.75717634 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75605075 |
| 97 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.75599050 |
| 98 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.75067521 |
| 99 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.74282825 |
| 100 | AR_20517297_ChIP-Seq_VCAP_Human | 0.74273121 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.20021601 |
| 2 | MP0009333_abnormal_splenocyte_physiolog | 3.60499588 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.59553387 |
| 4 | MP0005645_abnormal_hypothalamus_physiol | 3.52984179 |
| 5 | MP0009785_altered_susceptibility_to | 3.47497914 |
| 6 | MP0003646_muscle_fatigue | 3.45011589 |
| 7 | MP0002166_altered_tumor_susceptibility | 2.85184373 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.80235937 |
| 9 | MP0001800_abnormal_humoral_immune | 2.79912059 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.74060905 |
| 11 | MP0003763_abnormal_thymus_physiology | 2.72339476 |
| 12 | MP0005174_abnormal_tail_pigmentation | 2.58766104 |
| 13 | MP0005025_abnormal_response_to | 2.47134203 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.34776425 |
| 15 | MP0001819_abnormal_immune_cell | 2.28464995 |
| 16 | MP0009764_decreased_sensitivity_to | 2.21241692 |
| 17 | MP0005387_immune_system_phenotype | 2.20098342 |
| 18 | MP0001790_abnormal_immune_system | 2.20098342 |
| 19 | MP0002723_abnormal_immune_serum | 2.19133241 |
| 20 | MP0001188_hyperpigmentation | 2.07794425 |
| 21 | MP0005083_abnormal_biliary_tract | 2.07586610 |
| 22 | MP0004947_skin_inflammation | 2.04556560 |
| 23 | MP0005075_abnormal_melanosome_morpholog | 2.03052784 |
| 24 | MP0003045_fibrosis | 1.94743787 |
| 25 | MP0002452_abnormal_antigen_presenting | 1.92108050 |
| 26 | MP0002006_tumorigenesis | 1.91759128 |
| 27 | MP0005084_abnormal_gallbladder_morpholo | 1.90011661 |
| 28 | MP0003724_increased_susceptibility_to | 1.85849643 |
| 29 | MP0000716_abnormal_immune_system | 1.80674699 |
| 30 | MP0000685_abnormal_immune_system | 1.77347010 |
| 31 | MP0001873_stomach_inflammation | 1.71487371 |
| 32 | MP0005166_decreased_susceptibility_to | 1.70566608 |
| 33 | MP0000015_abnormal_ear_pigmentation | 1.70269322 |
| 34 | MP0000703_abnormal_thymus_morphology | 1.69550856 |
| 35 | MP0002398_abnormal_bone_marrow | 1.66559201 |
| 36 | MP0010155_abnormal_intestine_physiology | 1.64837452 |
| 37 | MP0003136_yellow_coat_color | 1.64653188 |
| 38 | MP0002933_joint_inflammation | 1.60256065 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.59690162 |
| 40 | MP0009379_abnormal_foot_pigmentation | 1.59176553 |
| 41 | MP0004883_abnormal_blood_vessel | 1.59037263 |
| 42 | MP0001919_abnormal_reproductive_system | 1.54720036 |
| 43 | MP0000858_altered_metastatic_potential | 1.54364216 |
| 44 | MP0004130_abnormal_muscle_cell | 1.51393288 |
| 45 | MP0004381_abnormal_hair_follicle | 1.49108661 |
| 46 | MP0002419_abnormal_innate_immunity | 1.49062254 |
| 47 | MP0005389_reproductive_system_phenotype | 1.46160977 |
| 48 | MP0001905_abnormal_dopamine_level | 1.42965307 |
| 49 | MP0003448_altered_tumor_morphology | 1.41283962 |
| 50 | MP0002722_abnormal_immune_system | 1.40480968 |
| 51 | MP0002102_abnormal_ear_morphology | 1.36000148 |
| 52 | MP0006082_CNS_inflammation | 1.34278000 |
| 53 | MP0000372_irregular_coat_pigmentation | 1.33271661 |
| 54 | MP0001986_abnormal_taste_sensitivity | 1.32161510 |
| 55 | MP0002429_abnormal_blood_cell | 1.29983778 |
| 56 | MP0005464_abnormal_platelet_physiology | 1.29005365 |
| 57 | MP0009763_increased_sensitivity_to | 1.28775727 |
| 58 | MP0003436_decreased_susceptibility_to | 1.26695653 |
| 59 | MP0001845_abnormal_inflammatory_respons | 1.26308293 |
| 60 | MP0002837_dystrophic_cardiac_calcinosis | 1.26223185 |
| 61 | MP0003866_abnormal_defecation | 1.21599054 |
| 62 | MP0000689_abnormal_spleen_morphology | 1.21395691 |
| 63 | MP0002638_abnormal_pupillary_reflex | 1.17627277 |
| 64 | MP0002160_abnormal_reproductive_system | 1.16280025 |
| 65 | MP0002132_abnormal_respiratory_system | 1.16272512 |
| 66 | MP0005646_abnormal_pituitary_gland | 1.14680589 |
| 67 | MP0003075_altered_response_to | 1.10212499 |
| 68 | MP0002019_abnormal_tumor_incidence | 1.06839467 |
| 69 | MP0001968_abnormal_touch/_nociception | 1.04713512 |
| 70 | MP0004484_altered_response_of | 1.03844773 |
| 71 | MP0008995_early_reproductive_senescence | 1.02867481 |
| 72 | MP0002095_abnormal_skin_pigmentation | 1.00140310 |
| 73 | MP0002405_respiratory_system_inflammati | 1.00070133 |
| 74 | MP0008872_abnormal_physiological_respon | 1.00030055 |
| 75 | MP0000537_abnormal_urethra_morphology | 0.99921852 |
| 76 | MP0005670_abnormal_white_adipose | 0.97403025 |
| 77 | MP0003938_abnormal_ear_development | 0.93847615 |
| 78 | MP0002168_other_aberrant_phenotype | 0.86862176 |
| 79 | MP0008469_abnormal_protein_level | 0.85872411 |
| 80 | MP0002138_abnormal_hepatobiliary_system | 0.85776122 |
| 81 | MP0005423_abnormal_somatic_nervous | 0.85228111 |
| 82 | MP0004043_abnormal_pH_regulation | 0.79225179 |
| 83 | MP0004134_abnormal_chest_morphology | 0.78609837 |
| 84 | MP0009765_abnormal_xenobiotic_induced | 0.77970898 |
| 85 | MP0001533_abnormal_skeleton_physiology | 0.74973612 |
| 86 | MP0002736_abnormal_nociception_after | 0.74144454 |
| 87 | MP0003880_abnormal_central_pattern | 0.71074768 |
| 88 | MP0003950_abnormal_plasma_membrane | 0.70767010 |
| 89 | MP0000470_abnormal_stomach_morphology | 0.64088328 |
| 90 | MP0003633_abnormal_nervous_system | 0.63624281 |
| 91 | MP0002272_abnormal_nervous_system | 0.63279862 |
| 92 | MP0000538_abnormal_urinary_bladder | 0.61775649 |
| 93 | MP0002693_abnormal_pancreas_physiology | 0.58770063 |
| 94 | MP0008873_increased_physiological_sensi | 0.57866137 |
| 95 | MP0008877_abnormal_DNA_methylation | 0.57144549 |
| 96 | MP0008961_abnormal_basal_metabolism | 0.55871642 |
| 97 | MP0003172_abnormal_lysosome_physiology | 0.52942398 |
| 98 | MP0000249_abnormal_blood_vessel | 0.50157449 |
| 99 | MP0003195_calcinosis | 0.48557411 |
| 100 | MP0003806_abnormal_nucleotide_metabolis | 0.47988109 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IgG deficiency (HP:0004315) | 5.49339307 |
| 2 | Autoimmune hemolytic anemia (HP:0001890) | 5.17672789 |
| 3 | T lymphocytopenia (HP:0005403) | 5.06249548 |
| 4 | Increased IgM level (HP:0003496) | 5.04087927 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.60284622 |
| 6 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.51254193 |
| 7 | Severe visual impairment (HP:0001141) | 4.46686321 |
| 8 | Abnormality of T cell number (HP:0011839) | 4.41034419 |
| 9 | Severe combined immunodeficiency (HP:0004430) | 4.37898637 |
| 10 | Decreased central vision (HP:0007663) | 4.31565380 |
| 11 | Increased intramyocellular lipid droplets (HP:0012240) | 4.16211980 |
| 12 | Respiratory difficulties (HP:0002880) | 4.01922704 |
| 13 | Recurrent bronchitis (HP:0002837) | 3.90950731 |
| 14 | Hyperglycinemia (HP:0002154) | 3.68020311 |
| 15 | Increased hepatocellular lipid droplets (HP:0006565) | 3.64803488 |
| 16 | Increased muscle lipid content (HP:0009058) | 3.59850995 |
| 17 | Thyroiditis (HP:0100646) | 3.57448799 |
| 18 | Congenital stationary night blindness (HP:0007642) | 3.54941094 |
| 19 | Combined immunodeficiency (HP:0005387) | 3.47201690 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 3.40977192 |
| 21 | Lipid accumulation in hepatocytes (HP:0006561) | 3.40846052 |
| 22 | B lymphocytopenia (HP:0010976) | 3.38893889 |
| 23 | Eosinophilia (HP:0001880) | 3.29326830 |
| 24 | Hematochezia (HP:0002573) | 3.29223047 |
| 25 | Abnormality of B cell number (HP:0010975) | 3.27210221 |
| 26 | Abnormality of eosinophils (HP:0001879) | 3.19293962 |
| 27 | Acute hepatic failure (HP:0006554) | 3.16266058 |
| 28 | Chronic sinusitis (HP:0011109) | 3.03461346 |
| 29 | Exertional dyspnea (HP:0002875) | 2.99045725 |
| 30 | Hypergammaglobulinemia (HP:0010702) | 2.96859631 |
| 31 | Encephalitis (HP:0002383) | 2.92878487 |
| 32 | Hypoproteinemia (HP:0003075) | 2.80921756 |
| 33 | Conical tooth (HP:0000698) | 2.73964967 |
| 34 | Lymphopenia (HP:0001888) | 2.73726494 |
| 35 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.65733601 |
| 36 | Abnormality of DNA repair (HP:0003254) | 2.54506318 |
| 37 | Leukocytosis (HP:0001974) | 2.53340870 |
| 38 | Amyotrophic lateral sclerosis (HP:0007354) | 2.50327135 |
| 39 | Nemaline bodies (HP:0003798) | 2.50063201 |
| 40 | Granulocytopenia (HP:0001913) | 2.45842472 |
| 41 | Thick nail (HP:0001805) | 2.45837750 |
| 42 | Erythema (HP:0010783) | 2.45819802 |
| 43 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.45231322 |
| 44 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.42665068 |
| 45 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.40537039 |
| 46 | Eczematoid dermatitis (HP:0000976) | 2.36633370 |
| 47 | Mesangial abnormality (HP:0001966) | 2.34815839 |
| 48 | Recurrent otitis media (HP:0000403) | 2.34667095 |
| 49 | Rhabdomyolysis (HP:0003201) | 2.32340119 |
| 50 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.31197940 |
| 51 | Dicarboxylic aciduria (HP:0003215) | 2.31197940 |
| 52 | Abnormality of T cells (HP:0002843) | 2.29572501 |
| 53 | Recurrent bacterial skin infections (HP:0005406) | 2.28769795 |
| 54 | Gingival bleeding (HP:0000225) | 2.27818000 |
| 55 | Abnormality of the columella (HP:0009929) | 2.24624816 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.22454281 |
| 57 | Palpebral edema (HP:0100540) | 2.17146958 |
| 58 | Inflammation of the large intestine (HP:0002037) | 2.16383723 |
| 59 | Hyperalaninemia (HP:0003348) | 2.15427796 |
| 60 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.15427796 |
| 61 | Abnormality of alanine metabolism (HP:0010916) | 2.15427796 |
| 62 | Bronchitis (HP:0012387) | 2.14144917 |
| 63 | Mitochondrial inheritance (HP:0001427) | 2.12986393 |
| 64 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.10399926 |
| 65 | Prostate neoplasm (HP:0100787) | 2.09187649 |
| 66 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.08844373 |
| 67 | Nasal polyposis (HP:0100582) | 2.08691583 |
| 68 | Limb hypertonia (HP:0002509) | 2.08488390 |
| 69 | Atrioventricular block (HP:0001678) | 2.07554475 |
| 70 | Abnormality of the fingertips (HP:0001211) | 2.06200482 |
| 71 | Spontaneous hematomas (HP:0007420) | 2.04364533 |
| 72 | IgA deficiency (HP:0002720) | 2.02658815 |
| 73 | Hyperglycinuria (HP:0003108) | 2.02177096 |
| 74 | Abnormality of renal resorption (HP:0011038) | 2.01385583 |
| 75 | Facial diplegia (HP:0001349) | 2.01220284 |
| 76 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.98843348 |
| 77 | Recurrent abscess formation (HP:0002722) | 1.98246994 |
| 78 | Abnormality of serum amino acid levels (HP:0003112) | 1.97735550 |
| 79 | Hyperphosphaturia (HP:0003109) | 1.97327633 |
| 80 | Pancytopenia (HP:0001876) | 1.94511713 |
| 81 | Stomatitis (HP:0010280) | 1.93826782 |
| 82 | Acute encephalopathy (HP:0006846) | 1.91843423 |
| 83 | Hyperammonemia (HP:0001987) | 1.91573707 |
| 84 | Alveolar cell carcinoma (HP:0006519) | 1.90662055 |
| 85 | Gastrointestinal inflammation (HP:0004386) | 1.89898826 |
| 86 | Ventricular tachycardia (HP:0004756) | 1.89896164 |
| 87 | Recurrent fungal infections (HP:0002841) | 1.88982472 |
| 88 | Meningitis (HP:0001287) | 1.85892257 |
| 89 | Long nose (HP:0003189) | 1.84826120 |
| 90 | Muscle fiber inclusion bodies (HP:0100299) | 1.84823951 |
| 91 | Increased CSF lactate (HP:0002490) | 1.84765123 |
| 92 | Hepatocellular necrosis (HP:0001404) | 1.83238835 |
| 93 | Clubbing of toes (HP:0100760) | 1.82557704 |
| 94 | IgM deficiency (HP:0002850) | 1.81595843 |
| 95 | Chronic diarrhea (HP:0002028) | 1.80240073 |
| 96 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.79775578 |
| 97 | Glucose intolerance (HP:0000833) | 1.79732980 |
| 98 | Verrucae (HP:0200043) | 1.78357136 |
| 99 | Papilloma (HP:0012740) | 1.78357136 |
| 100 | Hepatic necrosis (HP:0002605) | 1.78088295 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 6.97586559 |
| 2 | MAP3K10 | 4.69987675 |
| 3 | TESK2 | 4.05977607 |
| 4 | TXK | 3.81370062 |
| 5 | VRK2 | 3.33529882 |
| 6 | MAP4K1 | 2.97385765 |
| 7 | PIK3CA | 2.33964180 |
| 8 | ADRBK2 | 1.98315506 |
| 9 | LRRK2 | 1.84903799 |
| 10 | ITK | 1.78779067 |
| 11 | RIPK4 | 1.78546498 |
| 12 | BCKDK | 1.77862267 |
| 13 | AKT3 | 1.63475607 |
| 14 | VRK1 | 1.60723950 |
| 15 | TESK1 | 1.59763002 |
| 16 | GRK1 | 1.53661731 |
| 17 | ZAK | 1.48762023 |
| 18 | PIM1 | 1.43189999 |
| 19 | BTK | 1.42962513 |
| 20 | IKBKE | 1.42339414 |
| 21 | GRK6 | 1.40963951 |
| 22 | GRK7 | 1.40684840 |
| 23 | FRK | 1.35238396 |
| 24 | TYK2 | 1.31114146 |
| 25 | MAP3K5 | 1.28845595 |
| 26 | PDK2 | 1.28594451 |
| 27 | PRKCQ | 1.27189692 |
| 28 | PINK1 | 1.24433878 |
| 29 | TLK1 | 1.23124159 |
| 30 | CAMKK2 | 1.23114246 |
| 31 | SYK | 1.18201730 |
| 32 | RPS6KA5 | 1.17502900 |
| 33 | MAP3K12 | 1.17102530 |
| 34 | CSK | 1.16430151 |
| 35 | BUB1 | 1.12820312 |
| 36 | ROCK1 | 1.11991793 |
| 37 | NLK | 1.09547168 |
| 38 | ZAP70 | 1.08762128 |
| 39 | IKBKB | 1.07133600 |
| 40 | PIM2 | 1.06480127 |
| 41 | JAK1 | 1.06068076 |
| 42 | JAK3 | 1.04624969 |
| 43 | TEC | 1.00816727 |
| 44 | NEK9 | 1.00538126 |
| 45 | BLK | 0.93352833 |
| 46 | LYN | 0.90676556 |
| 47 | EPHB2 | 0.90483773 |
| 48 | RPS6KA4 | 0.89627043 |
| 49 | NEK6 | 0.87033713 |
| 50 | CSF1R | 0.84047170 |
| 51 | ARAF | 0.80888682 |
| 52 | LCK | 0.79580818 |
| 53 | MYLK | 0.78199478 |
| 54 | KIT | 0.77076228 |
| 55 | PDK1 | 0.76107488 |
| 56 | BMPR2 | 0.76039710 |
| 57 | ILK | 0.71358819 |
| 58 | ERBB2 | 0.70605344 |
| 59 | LIMK1 | 0.69762869 |
| 60 | SCYL2 | 0.68055811 |
| 61 | BRAF | 0.65388696 |
| 62 | FES | 0.63328838 |
| 63 | PRPF4B | 0.62845543 |
| 64 | SGK2 | 0.61324965 |
| 65 | TRIB3 | 0.61298389 |
| 66 | TBK1 | 0.61058771 |
| 67 | TIE1 | 0.60490767 |
| 68 | PKN2 | 0.58601320 |
| 69 | HCK | 0.53870437 |
| 70 | MAP3K11 | 0.51749677 |
| 71 | ICK | 0.51584361 |
| 72 | OBSCN | 0.51267180 |
| 73 | ADRBK1 | 0.50588863 |
| 74 | STK10 | 0.50396471 |
| 75 | INSRR | 0.49709112 |
| 76 | FYN | 0.48067677 |
| 77 | NUAK1 | 0.47064472 |
| 78 | GRK5 | 0.47005225 |
| 79 | MAPK13 | 0.45065844 |
| 80 | JAK2 | 0.44652439 |
| 81 | PAK1 | 0.42749622 |
| 82 | IGF1R | 0.38708016 |
| 83 | PRKD1 | 0.36654026 |
| 84 | SGK3 | 0.35327268 |
| 85 | PTK2B | 0.32176572 |
| 86 | CAMK2G | 0.31115681 |
| 87 | CAMKK1 | 0.30726189 |
| 88 | MELK | 0.29732027 |
| 89 | CDK3 | 0.28056422 |
| 90 | CSNK1D | 0.27965183 |
| 91 | INSR | 0.27593791 |
| 92 | LATS1 | 0.26762722 |
| 93 | PIK3CG | 0.26668745 |
| 94 | ABL1 | 0.25572997 |
| 95 | PRKCA | 0.25392822 |
| 96 | CAMK1 | 0.25301186 |
| 97 | MUSK | 0.24549417 |
| 98 | EGFR | 0.23020180 |
| 99 | MAP4K2 | 0.22723415 |
| 100 | PLK1 | 0.22689680 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.60353220 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.70791111 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.04223959 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.78785006 |
| 5 | Malaria_Homo sapiens_hsa05144 | 2.78161521 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.74753731 |
| 7 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.73033554 |
| 8 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.55687846 |
| 9 | ABC transporters_Homo sapiens_hsa02010 | 2.45632225 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.34135658 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.16402733 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.07161605 |
| 13 | Measles_Homo sapiens_hsa05162 | 2.05957886 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.83157875 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 1.79541621 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.76757587 |
| 17 | Allograft rejection_Homo sapiens_hsa05330 | 1.73450970 |
| 18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.71519101 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.68944559 |
| 20 | Peroxisome_Homo sapiens_hsa04146 | 1.66615399 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.57328921 |
| 22 | Shigellosis_Homo sapiens_hsa05131 | 1.51798850 |
| 23 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.42829827 |
| 24 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.39596877 |
| 25 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.32735200 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.32679684 |
| 27 | Huntingtons disease_Homo sapiens_hsa05016 | 1.30789288 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.28710961 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.24332774 |
| 30 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.11450575 |
| 31 | Salmonella infection_Homo sapiens_hsa05132 | 1.10275997 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.09189292 |
| 33 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.07263494 |
| 34 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.06383982 |
| 35 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.03713092 |
| 36 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.03626739 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 1.03203948 |
| 38 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.02978292 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 1.02610474 |
| 40 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.00963517 |
| 41 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.98021880 |
| 42 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.97855270 |
| 43 | Homologous recombination_Homo sapiens_hsa03440 | 0.96109039 |
| 44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.94808090 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.93764692 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90896787 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.89754336 |
| 48 | Retinol metabolism_Homo sapiens_hsa00830 | 0.88757004 |
| 49 | Pertussis_Homo sapiens_hsa05133 | 0.85868660 |
| 50 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.85608265 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85595654 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.83968663 |
| 53 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.81297685 |
| 54 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.78141084 |
| 55 | Legionellosis_Homo sapiens_hsa05134 | 0.76681776 |
| 56 | Leishmaniasis_Homo sapiens_hsa05140 | 0.76443931 |
| 57 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.74699749 |
| 58 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.69506882 |
| 59 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.69200450 |
| 60 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.65348107 |
| 61 | Sulfur relay system_Homo sapiens_hsa04122 | 0.64527662 |
| 62 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.62674490 |
| 63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61777423 |
| 64 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.60858459 |
| 65 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.57433898 |
| 66 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57317459 |
| 67 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.55726419 |
| 68 | Taste transduction_Homo sapiens_hsa04742 | 0.55399001 |
| 69 | Platelet activation_Homo sapiens_hsa04611 | 0.54577363 |
| 70 | Asthma_Homo sapiens_hsa05310 | 0.50548153 |
| 71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.50106458 |
| 72 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.48083898 |
| 73 | Influenza A_Homo sapiens_hsa05164 | 0.41050916 |
| 74 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.40597339 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38988518 |
| 76 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.37033566 |
| 77 | Endocytosis_Homo sapiens_hsa04144 | 0.36313050 |
| 78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.34599904 |
| 79 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.31115562 |
| 80 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.30329102 |
| 81 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.30247379 |
| 82 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.30064793 |
| 83 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.29657586 |
| 84 | Apoptosis_Homo sapiens_hsa04210 | 0.29187724 |
| 85 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.29127166 |
| 86 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.28529393 |
| 87 | Tuberculosis_Homo sapiens_hsa05152 | 0.26825971 |
| 88 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.24510883 |
| 89 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.23521825 |
| 90 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.23303044 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.23066026 |
| 92 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.20451136 |
| 93 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.19876136 |
| 94 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.18651095 |
| 95 | Phagosome_Homo sapiens_hsa04145 | 0.16692047 |
| 96 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.14709287 |
| 97 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.13042015 |
| 98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.12738503 |
| 99 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.12543347 |
| 100 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.11889720 |

