

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | eosinophil chemotaxis (GO:0048245) | 9.55290555 |
| 2 | negative regulation by host of viral transcription (GO:0043922) | 9.48842221 |
| 3 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 8.93230785 |
| 4 | eosinophil migration (GO:0072677) | 8.60410808 |
| 5 | DNA deamination (GO:0045006) | 8.49294914 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.84479750 |
| 7 | regulation of lymphocyte chemotaxis (GO:1901623) | 7.48425508 |
| 8 | monocyte chemotaxis (GO:0002548) | 7.07318341 |
| 9 | regulation of chronic inflammatory response (GO:0002676) | 6.82758274 |
| 10 | macrophage chemotaxis (GO:0048246) | 6.79338684 |
| 11 | regulation of activation of Janus kinase activity (GO:0010533) | 6.55713231 |
| 12 | regulation of regulatory T cell differentiation (GO:0045589) | 6.38082607 |
| 13 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 6.33771109 |
| 14 | positive regulation of T cell apoptotic process (GO:0070234) | 6.28139840 |
| 15 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 6.19495046 |
| 16 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 6.16548066 |
| 17 | negative regulation of T cell apoptotic process (GO:0070233) | 6.12920018 |
| 18 | regulation of mononuclear cell migration (GO:0071675) | 6.11448728 |
| 19 | regulation of T cell chemotaxis (GO:0010819) | 6.03357846 |
| 20 | positive regulation of T cell chemotaxis (GO:0010820) | 6.03357846 |
| 21 | positive regulation of monocyte chemotaxis (GO:0090026) | 5.98345341 |
| 22 | positive regulation of interleukin-8 secretion (GO:2000484) | 5.83987319 |
| 23 | positive regulation of lymphocyte migration (GO:2000403) | 5.55978448 |
| 24 | regulation of macrophage chemotaxis (GO:0010758) | 5.50589538 |
| 25 | positive thymic T cell selection (GO:0045059) | 5.45588780 |
| 26 | modulation by host of viral transcription (GO:0043921) | 5.21024593 |
| 27 | modulation by host of symbiont transcription (GO:0052472) | 5.21024593 |
| 28 | negative regulation of viral transcription (GO:0032897) | 5.11822775 |
| 29 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 5.09360201 |
| 30 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 5.08570877 |
| 31 | regulation of natural killer cell mediated immunity (GO:0002715) | 5.08570877 |
| 32 | positive T cell selection (GO:0043368) | 5.08287195 |
| 33 | regulation of T cell tolerance induction (GO:0002664) | 5.00716100 |
| 34 | cellular response to interleukin-15 (GO:0071350) | 4.94917409 |
| 35 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 4.94069609 |
| 36 | response to interleukin-15 (GO:0070672) | 4.86742352 |
| 37 | positive regulation of tolerance induction (GO:0002645) | 4.83966495 |
| 38 | positive regulation of translational initiation (GO:0045948) | 4.82010445 |
| 39 | membrane raft organization (GO:0031579) | 4.70854817 |
| 40 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.62850128 |
| 41 | dendritic cell chemotaxis (GO:0002407) | 4.46526714 |
| 42 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.37569733 |
| 43 | negative regulation of B cell proliferation (GO:0030889) | 4.26222000 |
| 44 | regulation of lymphocyte migration (GO:2000401) | 4.24448443 |
| 45 | regulation of T cell apoptotic process (GO:0070232) | 4.24266279 |
| 46 | positive regulation of leukocyte apoptotic process (GO:2000108) | 4.19583563 |
| 47 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.15684000 |
| 48 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 4.14950560 |
| 49 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 4.09063602 |
| 50 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 4.05577269 |
| 51 | regulation of tolerance induction (GO:0002643) | 4.05330411 |
| 52 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.04669459 |
| 53 | granulocyte activation (GO:0036230) | 4.03485915 |
| 54 | negative regulation of viral genome replication (GO:0045071) | 4.01735480 |
| 55 | regulation of monocyte chemotaxis (GO:0090025) | 4.00014535 |
| 56 | regulation of interleukin-8 secretion (GO:2000482) | 3.97100205 |
| 57 | localization within membrane (GO:0051668) | 3.96770714 |
| 58 | positive regulation of cell killing (GO:0031343) | 3.92315380 |
| 59 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.89284714 |
| 60 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.81336268 |
| 61 | negative regulation of B cell activation (GO:0050869) | 3.78867493 |
| 62 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.72391648 |
| 63 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.72223696 |
| 64 | positive regulation of T cell migration (GO:2000406) | 3.65866376 |
| 65 | nucleoside diphosphate catabolic process (GO:0009134) | 3.64045644 |
| 66 | thymic T cell selection (GO:0045061) | 3.62785415 |
| 67 | dendritic cell migration (GO:0036336) | 3.61531411 |
| 68 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.55870951 |
| 69 | T cell costimulation (GO:0031295) | 3.55107860 |
| 70 | regulation of cell killing (GO:0031341) | 3.54309850 |
| 71 | lymphocyte costimulation (GO:0031294) | 3.50414294 |
| 72 | modification by host of symbiont morphology or physiology (GO:0051851) | 3.45764203 |
| 73 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.43732614 |
| 74 | positive regulation of macrophage differentiation (GO:0045651) | 3.43385918 |
| 75 | regulation of calcium-mediated signaling (GO:0050848) | 3.42392889 |
| 76 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.41637809 |
| 77 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.40089143 |
| 78 | regulation of T cell migration (GO:2000404) | 3.37393798 |
| 79 | negative regulation of T cell activation (GO:0050868) | 3.32709929 |
| 80 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.30955216 |
| 81 | negative regulation of T cell differentiation (GO:0045581) | 3.30674322 |
| 82 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.29423209 |
| 83 | DNA demethylation (GO:0080111) | 3.24996153 |
| 84 | T cell selection (GO:0045058) | 3.22910432 |
| 85 | regulation of lymphocyte apoptotic process (GO:0070228) | 3.21468402 |
| 86 | interaction with symbiont (GO:0051702) | 3.17539877 |
| 87 | positive regulation of smooth muscle cell migration (GO:0014911) | 3.13394447 |
| 88 | negative regulation of viral process (GO:0048525) | 3.13065441 |
| 89 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.12275126 |
| 90 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.09804078 |
| 91 | T cell migration (GO:0072678) | 3.08457950 |
| 92 | positive regulation of cell adhesion mediated by integrin (GO:0033630) | 3.07084897 |
| 93 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.02189699 |
| 94 | actin nucleation (GO:0045010) | 3.02129202 |
| 95 | negative regulation of leukocyte apoptotic process (GO:2000107) | 2.98735374 |
| 96 | negative regulation of lymphocyte activation (GO:0051250) | 2.96715087 |
| 97 | histone mRNA catabolic process (GO:0071044) | 2.94920972 |
| 98 | cytidine deamination (GO:0009972) | 10.1608111 |
| 99 | cytidine metabolic process (GO:0046087) | 10.1608111 |
| 100 | cytidine catabolic process (GO:0006216) | 10.1608111 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.54520851 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.73493411 |
| 3 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.31478846 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.64049817 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.44877094 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.09024764 |
| 7 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.84914570 |
| 8 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.73748104 |
| 9 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.63764974 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 2.44609797 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.37822277 |
| 12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.15436891 |
| 13 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.13336443 |
| 14 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.06249326 |
| 15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.04920444 |
| 16 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.00107831 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 14.3383113 |
| 18 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.77890393 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.65765960 |
| 20 | MAF_26560356_Chip-Seq_TH2_Human | 1.63329983 |
| 21 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.63039412 |
| 22 | MYB_26560356_Chip-Seq_TH1_Human | 1.60245095 |
| 23 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56844883 |
| 24 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.56093119 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.52327272 |
| 26 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.51681220 |
| 27 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.49293316 |
| 28 | VDR_22108803_ChIP-Seq_LS180_Human | 1.44641157 |
| 29 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.43181623 |
| 30 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.41859728 |
| 31 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.37273025 |
| 32 | GATA3_26560356_Chip-Seq_TH2_Human | 1.34219945 |
| 33 | UTX_26944678_Chip-Seq_JUKART_Human | 1.26302801 |
| 34 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23136311 |
| 35 | MAF_26560356_Chip-Seq_TH1_Human | 1.22732970 |
| 36 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21403311 |
| 37 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.20029956 |
| 38 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16566480 |
| 39 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.15372841 |
| 40 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.13816841 |
| 41 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.09534530 |
| 42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08085964 |
| 43 | GATA3_26560356_Chip-Seq_TH1_Human | 1.07274237 |
| 44 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.05526008 |
| 45 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04899655 |
| 46 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.04853309 |
| 47 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.02260083 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.01070543 |
| 49 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.00188414 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.97470268 |
| 51 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.96895924 |
| 52 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.95385778 |
| 53 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.91995795 |
| 54 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91787777 |
| 55 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.88550183 |
| 56 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.87486114 |
| 57 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.87067576 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.86214905 |
| 59 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.85738236 |
| 60 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.84360801 |
| 61 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.82596156 |
| 62 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.82034926 |
| 63 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.80510135 |
| 64 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.80074689 |
| 65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.80074689 |
| 66 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.78628457 |
| 67 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.78384915 |
| 68 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.77192782 |
| 69 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.75288922 |
| 70 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75253036 |
| 71 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.74489581 |
| 72 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.73835494 |
| 73 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.73300336 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.71742652 |
| 75 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.71703314 |
| 76 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.71401275 |
| 77 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.69824700 |
| 78 | TP53_16413492_ChIP-PET_HCT116_Human | 0.68943686 |
| 79 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.68764732 |
| 80 | P300_27268052_Chip-Seq_Bcells_Human | 0.67482251 |
| 81 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.66503948 |
| 82 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.66305946 |
| 83 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.66279216 |
| 84 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.66196306 |
| 85 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.65562180 |
| 86 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.64812797 |
| 87 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.64597055 |
| 88 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.63823572 |
| 89 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.63614832 |
| 90 | SA1_27219007_Chip-Seq_Bcells_Human | 0.61752796 |
| 91 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.61408860 |
| 92 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.61315303 |
| 93 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.60082457 |
| 94 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.59758664 |
| 95 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.58551432 |
| 96 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.58188913 |
| 97 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.56944083 |
| 98 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.56898344 |
| 99 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.56863450 |
| 100 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.56752422 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 7.38415728 |
| 2 | MP0006082_CNS_inflammation | 4.56231996 |
| 3 | MP0003763_abnormal_thymus_physiology | 3.93164698 |
| 4 | MP0001873_stomach_inflammation | 3.60473856 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 3.34700980 |
| 6 | MP0002148_abnormal_hypersensitivity_rea | 2.89202948 |
| 7 | MP0001188_hyperpigmentation | 2.75328129 |
| 8 | MP0009785_altered_susceptibility_to | 2.65992202 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.56644165 |
| 10 | MP0001800_abnormal_humoral_immune | 2.48011808 |
| 11 | MP0002723_abnormal_immune_serum | 2.43125697 |
| 12 | MP0004145_abnormal_muscle_electrophysio | 2.42817845 |
| 13 | MP0003866_abnormal_defecation | 2.37685932 |
| 14 | MP0010307_abnormal_tumor_latency | 2.31718114 |
| 15 | MP0002163_abnormal_gland_morphology | 2.24700138 |
| 16 | MP0001835_abnormal_antigen_presentation | 2.20377240 |
| 17 | MP0002405_respiratory_system_inflammati | 2.19650909 |
| 18 | MP0001790_abnormal_immune_system | 2.17739288 |
| 19 | MP0005387_immune_system_phenotype | 2.17739288 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.17304229 |
| 21 | MP0010155_abnormal_intestine_physiology | 2.16054828 |
| 22 | MP0003786_premature_aging | 2.13778626 |
| 23 | MP0001819_abnormal_immune_cell | 2.12204391 |
| 24 | MP0000569_abnormal_digit_pigmentation | 2.10067662 |
| 25 | MP0002398_abnormal_bone_marrow | 1.94165859 |
| 26 | MP0005025_abnormal_response_to | 1.91572561 |
| 27 | MP0002877_abnormal_melanocyte_morpholog | 1.90570745 |
| 28 | MP0002933_joint_inflammation | 1.90045896 |
| 29 | MP0000716_abnormal_immune_system | 1.83330278 |
| 30 | MP0003045_fibrosis | 1.78699808 |
| 31 | MP0002452_abnormal_antigen_presenting | 1.71249676 |
| 32 | MP0001853_heart_inflammation | 1.67746225 |
| 33 | MP0002722_abnormal_immune_system | 1.66912741 |
| 34 | MP0002138_abnormal_hepatobiliary_system | 1.65684625 |
| 35 | MP0008007_abnormal_cellular_replicative | 1.61865047 |
| 36 | MP0000703_abnormal_thymus_morphology | 1.61766674 |
| 37 | MP0005670_abnormal_white_adipose | 1.61577016 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.61013837 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.58299902 |
| 40 | MP0003075_altered_response_to | 1.54334122 |
| 41 | MP0005310_abnormal_salivary_gland | 1.50465831 |
| 42 | MP0001984_abnormal_olfaction | 1.49220713 |
| 43 | MP0001845_abnormal_inflammatory_respons | 1.47789948 |
| 44 | MP0002638_abnormal_pupillary_reflex | 1.44794454 |
| 45 | MP0005379_endocrine/exocrine_gland_phen | 1.42487587 |
| 46 | MP0002429_abnormal_blood_cell | 1.39878287 |
| 47 | MP0001502_abnormal_circadian_rhythm | 1.37417158 |
| 48 | MP0001905_abnormal_dopamine_level | 1.35121658 |
| 49 | MP0003878_abnormal_ear_physiology | 1.32149698 |
| 50 | MP0005377_hearing/vestibular/ear_phenot | 1.32149698 |
| 51 | MP0003448_altered_tumor_morphology | 1.27131798 |
| 52 | MP0005075_abnormal_melanosome_morpholog | 1.25006128 |
| 53 | MP0001661_extended_life_span | 1.22122907 |
| 54 | MP0000920_abnormal_myelination | 1.18992729 |
| 55 | MP0002419_abnormal_innate_immunity | 1.15697191 |
| 56 | MP0005174_abnormal_tail_pigmentation | 1.15339018 |
| 57 | MP0003183_abnormal_peptide_metabolism | 1.12737002 |
| 58 | MP0008873_increased_physiological_sensi | 1.02394986 |
| 59 | MP0008469_abnormal_protein_level | 1.01038672 |
| 60 | MP0002277_abnormal_respiratory_mucosa | 0.98876736 |
| 61 | MP0000685_abnormal_immune_system | 0.92949408 |
| 62 | MP0004381_abnormal_hair_follicle | 0.90319628 |
| 63 | MP0002909_abnormal_adrenal_gland | 0.87965575 |
| 64 | MP0002234_abnormal_pharynx_morphology | 0.84392512 |
| 65 | MP0004947_skin_inflammation | 0.81202545 |
| 66 | MP0004147_increased_porphyrin_level | 0.78746643 |
| 67 | MP0009763_increased_sensitivity_to | 0.78542569 |
| 68 | MP0004043_abnormal_pH_regulation | 0.76899324 |
| 69 | MP0009765_abnormal_xenobiotic_induced | 0.74845761 |
| 70 | MP0005645_abnormal_hypothalamus_physiol | 0.74583015 |
| 71 | MP0000372_irregular_coat_pigmentation | 0.71804278 |
| 72 | MP0001485_abnormal_pinna_reflex | 0.71188104 |
| 73 | MP0003137_abnormal_impulse_conducting | 0.68529570 |
| 74 | MP0003567_abnormal_fetal_cardiomyocyte | 0.67133552 |
| 75 | MP0002693_abnormal_pancreas_physiology | 0.65410087 |
| 76 | MP0005165_increased_susceptibility_to | 0.63565849 |
| 77 | MP0000343_altered_response_to | 0.63048917 |
| 78 | MP0000516_abnormal_urinary_system | 0.62525666 |
| 79 | MP0005367_renal/urinary_system_phenotyp | 0.62525666 |
| 80 | MP0009764_decreased_sensitivity_to | 0.61462837 |
| 81 | MP0003172_abnormal_lysosome_physiology | 0.60686902 |
| 82 | MP0006035_abnormal_mitochondrial_morpho | 0.60465862 |
| 83 | MP0009643_abnormal_urine_homeostasis | 0.59968050 |
| 84 | MP0000858_altered_metastatic_potential | 0.59735112 |
| 85 | MP0002396_abnormal_hematopoietic_system | 0.59608490 |
| 86 | MP0008770_decreased_survivor_rate | 0.59193716 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.58790370 |
| 88 | MP0001542_abnormal_bone_strength | 0.58469902 |
| 89 | MP0000371_diluted_coat_color | 0.57407321 |
| 90 | MP0003436_decreased_susceptibility_to | 0.56378401 |
| 91 | MP0003011_delayed_dark_adaptation | 0.55410705 |
| 92 | MP0004134_abnormal_chest_morphology | 0.54759697 |
| 93 | MP0002019_abnormal_tumor_incidence | 0.53336819 |
| 94 | MP0001881_abnormal_mammary_gland | 0.52027249 |
| 95 | MP0001243_abnormal_dermal_layer | 0.49628138 |
| 96 | MP0002998_abnormal_bone_remodeling | 0.48571985 |
| 97 | MP0001765_abnormal_ion_homeostasis | 0.48389364 |
| 98 | MP0005319_abnormal_enzyme/_coenzyme | 0.48370220 |
| 99 | MP0002136_abnormal_kidney_physiology | 0.48327869 |
| 100 | MP0002837_dystrophic_cardiac_calcinosis | 0.46310874 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of T cell number (HP:0011839) | 7.59905455 |
| 2 | T lymphocytopenia (HP:0005403) | 7.28201377 |
| 3 | Hypoproteinemia (HP:0003075) | 5.59770785 |
| 4 | Autoimmune hemolytic anemia (HP:0001890) | 5.56443374 |
| 5 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 5.02051634 |
| 6 | Abnormality of the prostate (HP:0008775) | 4.90511797 |
| 7 | Increased IgM level (HP:0003496) | 4.70236218 |
| 8 | Abnormality of T cells (HP:0002843) | 4.63546161 |
| 9 | Ureteral stenosis (HP:0000071) | 4.51407806 |
| 10 | IgG deficiency (HP:0004315) | 4.29936504 |
| 11 | Ureteral obstruction (HP:0006000) | 4.21281008 |
| 12 | Hemiplegia (HP:0002301) | 4.06764849 |
| 13 | Abnormality of eosinophils (HP:0001879) | 4.01321879 |
| 14 | Recurrent bronchitis (HP:0002837) | 3.90079974 |
| 15 | Chronic diarrhea (HP:0002028) | 3.89930332 |
| 16 | Chronic obstructive pulmonary disease (HP:0006510) | 3.84457874 |
| 17 | Obstructive lung disease (HP:0006536) | 3.84457874 |
| 18 | Severe combined immunodeficiency (HP:0004430) | 3.81692258 |
| 19 | Gangrene (HP:0100758) | 3.72830692 |
| 20 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.69331790 |
| 21 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.69331790 |
| 22 | Chest pain (HP:0100749) | 3.63459440 |
| 23 | Meningitis (HP:0001287) | 3.60050170 |
| 24 | Hemoptysis (HP:0002105) | 3.53242263 |
| 25 | Hypoplasia of the thymus (HP:0000778) | 3.43689076 |
| 26 | Thyroiditis (HP:0100646) | 3.39971605 |
| 27 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.39762411 |
| 28 | Recurrent cutaneous fungal infections (HP:0011370) | 3.39762411 |
| 29 | Vasculitis (HP:0002633) | 3.23663144 |
| 30 | Autoimmune thrombocytopenia (HP:0001973) | 3.13772542 |
| 31 | Eosinophilia (HP:0001880) | 3.12705292 |
| 32 | Gastrointestinal infarctions (HP:0005244) | 3.09872821 |
| 33 | Pulmonary infiltrates (HP:0002113) | 3.05571645 |
| 34 | Hypoalbuminemia (HP:0003073) | 3.01497866 |
| 35 | Abnormal albumin level (HP:0012116) | 3.01497866 |
| 36 | Combined immunodeficiency (HP:0005387) | 2.96152435 |
| 37 | Abnormality of male internal genitalia (HP:0000022) | 2.95179854 |
| 38 | Zonular cataract (HP:0010920) | 2.93196514 |
| 39 | Leukocytosis (HP:0001974) | 2.91231001 |
| 40 | Granulocytopenia (HP:0001913) | 2.85059444 |
| 41 | Encephalitis (HP:0002383) | 2.84586123 |
| 42 | Abnormality of the pleura (HP:0002103) | 2.80222350 |
| 43 | Tetraplegia (HP:0002445) | 2.80061915 |
| 44 | 3-Methylglutaconic aciduria (HP:0003535) | 2.66824414 |
| 45 | Focal motor seizures (HP:0011153) | 2.65325369 |
| 46 | Abnormality of the alveolar ridges (HP:0006477) | 2.63012213 |
| 47 | Visual hallucinations (HP:0002367) | 2.62076394 |
| 48 | Abnormality of T cell physiology (HP:0011840) | 2.61632890 |
| 49 | Pulmonary fibrosis (HP:0002206) | 2.61209991 |
| 50 | Carpal bone hypoplasia (HP:0001498) | 2.60712157 |
| 51 | Pulmonary embolism (HP:0002204) | 2.58708268 |
| 52 | J-shaped sella turcica (HP:0002680) | 2.53492623 |
| 53 | Amaurosis fugax (HP:0100576) | 2.52805180 |
| 54 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.50487535 |
| 55 | Agammaglobulinemia (HP:0004432) | 2.49205675 |
| 56 | Abnormality of the pericardium (HP:0001697) | 2.40584039 |
| 57 | Abnormality of macrophages (HP:0004311) | 2.39178022 |
| 58 | Recurrent skin infections (HP:0001581) | 2.36854305 |
| 59 | Albinism (HP:0001022) | 2.36765245 |
| 60 | Bronchitis (HP:0012387) | 2.35033286 |
| 61 | Diplopia (HP:0000651) | 2.34343400 |
| 62 | Abnormality of binocular vision (HP:0011514) | 2.34343400 |
| 63 | Recurrent otitis media (HP:0000403) | 2.30971731 |
| 64 | Aplastic anemia (HP:0001915) | 2.30383904 |
| 65 | Pustule (HP:0200039) | 2.29425427 |
| 66 | Abnormality of midbrain morphology (HP:0002418) | 2.23447571 |
| 67 | Molar tooth sign on MRI (HP:0002419) | 2.23447571 |
| 68 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.22974002 |
| 69 | Stomatitis (HP:0010280) | 2.20472029 |
| 70 | Periorbital edema (HP:0100539) | 2.19437391 |
| 71 | Recurrent fungal infections (HP:0002841) | 2.19410801 |
| 72 | Acute necrotizing encephalopathy (HP:0006965) | 2.18011278 |
| 73 | Facial edema (HP:0000282) | 2.15187382 |
| 74 | Lymphopenia (HP:0001888) | 2.13910280 |
| 75 | Joint swelling (HP:0001386) | 2.12060045 |
| 76 | Glomerulopathy (HP:0100820) | 2.08385609 |
| 77 | Polyneuropathy (HP:0001271) | 2.02497123 |
| 78 | Pancreatitis (HP:0001733) | 2.01257541 |
| 79 | Skin rash (HP:0000988) | 1.98536313 |
| 80 | Lymphoma (HP:0002665) | 1.98159724 |
| 81 | Periodontitis (HP:0000704) | 1.96410714 |
| 82 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.94534694 |
| 83 | Abnormality of the astrocytes (HP:0100707) | 1.93840912 |
| 84 | Astrocytoma (HP:0009592) | 1.93840912 |
| 85 | Melanoma (HP:0002861) | 1.93347397 |
| 86 | Retinopathy (HP:0000488) | 1.93078683 |
| 87 | Myositis (HP:0100614) | 1.91661192 |
| 88 | Recurrent viral infections (HP:0004429) | 1.90475735 |
| 89 | Recurrent bacterial skin infections (HP:0005406) | 1.89695907 |
| 90 | Alveolar cell carcinoma (HP:0006519) | 1.89126461 |
| 91 | Amyotrophic lateral sclerosis (HP:0007354) | 1.87688380 |
| 92 | Bifid tongue (HP:0010297) | 1.87295908 |
| 93 | Pancreatic cysts (HP:0001737) | 1.86108481 |
| 94 | Thrombophlebitis (HP:0004418) | 1.84674244 |
| 95 | Panhypogammaglobulinemia (HP:0003139) | 1.84653202 |
| 96 | Stomach cancer (HP:0012126) | 1.83040947 |
| 97 | Progressive macrocephaly (HP:0004481) | 1.82434514 |
| 98 | Abnormality of B cell number (HP:0010975) | 1.80159003 |
| 99 | Glioma (HP:0009733) | 1.79433207 |
| 100 | Recurrent abscess formation (HP:0002722) | 1.79186545 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 4.82089398 |
| 2 | BUB1 | 4.29242269 |
| 3 | ITK | 2.98656026 |
| 4 | MAP4K1 | 2.62949112 |
| 5 | GRK7 | 2.58739059 |
| 6 | PRKCQ | 2.31369847 |
| 7 | TRIM28 | 2.14503377 |
| 8 | ADRBK2 | 2.10732482 |
| 9 | FES | 2.07876930 |
| 10 | TXK | 10.7066666 |
| 11 | ZAK | 1.98614446 |
| 12 | JAK3 | 1.94668009 |
| 13 | CSK | 1.89054531 |
| 14 | BCKDK | 1.71298552 |
| 15 | TYRO3 | 1.58025653 |
| 16 | LCK | 1.53097507 |
| 17 | TBK1 | 1.35977340 |
| 18 | SYK | 1.34674071 |
| 19 | ZAP70 | 1.33452404 |
| 20 | MAP3K12 | 1.32907163 |
| 21 | PIK3CA | 1.22804062 |
| 22 | MAPKAPK3 | 1.20531851 |
| 23 | IKBKE | 1.19356599 |
| 24 | WNK4 | 1.08707193 |
| 25 | PIK3CG | 1.07101367 |
| 26 | BCR | 1.05602161 |
| 27 | MST4 | 1.04935939 |
| 28 | TESK2 | 1.01224562 |
| 29 | MYLK | 0.99526818 |
| 30 | SRPK1 | 0.90442249 |
| 31 | PDGFRB | 0.86705433 |
| 32 | FGFR1 | 0.85931268 |
| 33 | TEC | 0.84923217 |
| 34 | JAK2 | 0.81040727 |
| 35 | TIE1 | 0.80487130 |
| 36 | IKBKB | 0.79175334 |
| 37 | LYN | 0.79019612 |
| 38 | FYN | 0.78861346 |
| 39 | DAPK1 | 0.78725257 |
| 40 | BTK | 0.75573206 |
| 41 | CSF1R | 0.75138134 |
| 42 | AKT3 | 0.70878252 |
| 43 | GRK1 | 0.68223840 |
| 44 | RIPK4 | 0.63022847 |
| 45 | TNK2 | 0.60550994 |
| 46 | NTRK1 | 0.59584548 |
| 47 | NUAK1 | 0.59342233 |
| 48 | TGFBR2 | 0.58568190 |
| 49 | INSR | 0.55551961 |
| 50 | MAP2K6 | 0.55220783 |
| 51 | VRK2 | 0.54284793 |
| 52 | IGF1R | 0.53313328 |
| 53 | FRK | 0.49319062 |
| 54 | MAP2K7 | 0.47404818 |
| 55 | STK16 | 0.46610110 |
| 56 | MATK | 0.46037805 |
| 57 | CAMK2A | 0.44411442 |
| 58 | MAP3K5 | 0.44297544 |
| 59 | BMPR1B | 0.42865019 |
| 60 | VRK1 | 0.41919748 |
| 61 | ROCK1 | 0.38964947 |
| 62 | PIM1 | 0.38855206 |
| 63 | PRKCA | 0.35307267 |
| 64 | CAMK2D | 0.34799476 |
| 65 | CSNK1A1 | 0.34293046 |
| 66 | PIM2 | 0.33877836 |
| 67 | MAPKAPK2 | 0.33641840 |
| 68 | BLK | 0.32890526 |
| 69 | INSRR | 0.32324697 |
| 70 | PRKCH | 0.31544359 |
| 71 | PNCK | 0.31459299 |
| 72 | NEK1 | 0.31209888 |
| 73 | OBSCN | 0.30750279 |
| 74 | TAOK3 | 0.29493500 |
| 75 | PRKACA | 0.28420708 |
| 76 | IRAK4 | 0.26538887 |
| 77 | ADRBK1 | 0.26386920 |
| 78 | MAPK3 | 0.26093878 |
| 79 | JAK1 | 0.25980589 |
| 80 | LIMK1 | 0.25971047 |
| 81 | PDK1 | 0.25035651 |
| 82 | CAMK2G | 0.24976259 |
| 83 | ATR | 0.24360277 |
| 84 | MAP3K11 | 0.23912256 |
| 85 | AURKA | 0.23854161 |
| 86 | EIF2AK3 | 0.23246065 |
| 87 | CHUK | 0.22272159 |
| 88 | STK10 | 0.21217499 |
| 89 | CLK1 | 0.20607316 |
| 90 | DYRK1B | 0.19994690 |
| 91 | EIF2AK2 | 0.19648546 |
| 92 | MELK | 0.18340261 |
| 93 | PRKACG | 0.18139244 |
| 94 | MUSK | 0.17476609 |
| 95 | PRKCE | 0.16274662 |
| 96 | CSNK2A1 | 0.15282159 |
| 97 | GRK5 | 0.15099205 |
| 98 | BMPR2 | 0.13651437 |
| 99 | MAPK12 | 0.13647555 |
| 100 | PAK1 | 0.12893983 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.33771107 |
| 2 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.49227299 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.32027970 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.85961385 |
| 5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 3.78555808 |
| 6 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 3.75663974 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.15302427 |
| 8 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.05612029 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.97433451 |
| 10 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.80973114 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.80258682 |
| 12 | Salmonella infection_Homo sapiens_hsa05132 | 2.67283783 |
| 13 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.62355643 |
| 14 | Proteasome_Homo sapiens_hsa03050 | 2.59684074 |
| 15 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 2.35145245 |
| 16 | Measles_Homo sapiens_hsa05162 | 2.09161875 |
| 17 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 2.05284633 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.86445299 |
| 19 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.86102579 |
| 20 | Viral myocarditis_Homo sapiens_hsa05416 | 1.61082271 |
| 21 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.60495476 |
| 22 | Prion diseases_Homo sapiens_hsa05020 | 1.59215597 |
| 23 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.51511052 |
| 24 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.51154422 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.49430237 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.30638145 |
| 27 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.14820951 |
| 28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.04387832 |
| 29 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.03123354 |
| 30 | Parkinsons disease_Homo sapiens_hsa05012 | 1.01291596 |
| 31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.97020519 |
| 32 | Protein export_Homo sapiens_hsa03060 | 0.95620459 |
| 33 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.90823842 |
| 34 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.90084417 |
| 35 | Leishmaniasis_Homo sapiens_hsa05140 | 0.88350989 |
| 36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.78224765 |
| 37 | HTLV-I infection_Homo sapiens_hsa05166 | 0.77438348 |
| 38 | Apoptosis_Homo sapiens_hsa04210 | 0.76170450 |
| 39 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.72587849 |
| 40 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.68229096 |
| 41 | Shigellosis_Homo sapiens_hsa05131 | 0.68094290 |
| 42 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.62866277 |
| 43 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.61138331 |
| 44 | Malaria_Homo sapiens_hsa05144 | 0.60519271 |
| 45 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57544563 |
| 46 | Alzheimers disease_Homo sapiens_hsa05010 | 0.56658538 |
| 47 | Influenza A_Homo sapiens_hsa05164 | 0.54912759 |
| 48 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.54121592 |
| 49 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.53618636 |
| 50 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.52460459 |
| 51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.46764181 |
| 52 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.45245546 |
| 53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.44312248 |
| 54 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41598673 |
| 55 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.39863337 |
| 56 | RNA polymerase_Homo sapiens_hsa03020 | 0.38034777 |
| 57 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.32448829 |
| 58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.31372205 |
| 59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.30265921 |
| 60 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.27947948 |
| 61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.26829630 |
| 62 | Huntingtons disease_Homo sapiens_hsa05016 | 0.26531571 |
| 63 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.26192960 |
| 64 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.24988670 |
| 65 | Peroxisome_Homo sapiens_hsa04146 | 0.21000394 |
| 66 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.20161205 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.19471138 |
| 68 | Retinol metabolism_Homo sapiens_hsa00830 | 0.19132950 |
| 69 | Lysosome_Homo sapiens_hsa04142 | 0.18115609 |
| 70 | Endocytosis_Homo sapiens_hsa04144 | 0.16584254 |
| 71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.16320489 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.16251118 |
| 73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.15279942 |
| 74 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.15208600 |
| 75 | Tuberculosis_Homo sapiens_hsa05152 | 0.14968557 |
| 76 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.14799580 |
| 77 | Phototransduction_Homo sapiens_hsa04744 | 0.14380426 |
| 78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.13515638 |
| 79 | Phagosome_Homo sapiens_hsa04145 | 0.13053750 |
| 80 | Legionellosis_Homo sapiens_hsa05134 | 0.12787663 |
| 81 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.11643999 |
| 82 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.10459829 |
| 83 | Mismatch repair_Homo sapiens_hsa03430 | 0.10227571 |
| 84 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.07465065 |
| 85 | Alcoholism_Homo sapiens_hsa05034 | 0.06217736 |
| 86 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.05824630 |
| 87 | Homologous recombination_Homo sapiens_hsa03440 | 0.03423915 |
| 88 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.02812477 |
| 89 | RNA degradation_Homo sapiens_hsa03018 | -0.0767417 |
| 90 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | -0.0766865 |
| 91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.0679589 |
| 92 | Sulfur metabolism_Homo sapiens_hsa00920 | -0.0512101 |
| 93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | -0.0477240 |
| 94 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | -0.0389080 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | -0.0369042 |
| 96 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | -0.0237638 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.0231204 |
| 98 | Basal transcription factors_Homo sapiens_hsa03022 | -0.0208257 |
| 99 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | -0.0113777 |
| 100 | Olfactory transduction_Homo sapiens_hsa04740 | -0.0074852 |

