

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cell killing (GO:0031342) | 7.48921057 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 7.48921057 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.79169698 |
| 4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.74703364 |
| 5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.59913274 |
| 6 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.24416094 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.20102765 |
| 8 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.14631794 |
| 9 | cellular response to interleukin-15 (GO:0071350) | 6.12038298 |
| 10 | negative T cell selection (GO:0043383) | 6.09668690 |
| 11 | response to interleukin-15 (GO:0070672) | 6.08167742 |
| 12 | negative thymic T cell selection (GO:0045060) | 5.82336926 |
| 13 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.61845765 |
| 14 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.57946039 |
| 15 | regulation of gamma-delta T cell activation (GO:0046643) | 5.36619111 |
| 16 | negative regulation of T cell mediated immunity (GO:0002710) | 5.12606936 |
| 17 | tolerance induction (GO:0002507) | 5.07232229 |
| 18 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.84044382 |
| 19 | activated T cell proliferation (GO:0050798) | 4.62953228 |
| 20 | positive T cell selection (GO:0043368) | 4.62391263 |
| 21 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.62333023 |
| 22 | regulation of T cell tolerance induction (GO:0002664) | 4.61879981 |
| 23 | leukocyte aggregation (GO:0070486) | 4.55670580 |
| 24 | T cell selection (GO:0045058) | 4.53829801 |
| 25 | thymic T cell selection (GO:0045061) | 4.50595946 |
| 26 | regulation of regulatory T cell differentiation (GO:0045589) | 4.46296720 |
| 27 | T cell migration (GO:0072678) | 4.43003699 |
| 28 | positive thymic T cell selection (GO:0045059) | 4.18224805 |
| 29 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.14413591 |
| 30 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.13969029 |
| 31 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.13969029 |
| 32 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.13901769 |
| 33 | modulation by symbiont of host immune response (GO:0052553) | 4.13901769 |
| 34 | positive regulation by symbiont of host defense response (GO:0052509) | 4.13901769 |
| 35 | modulation by symbiont of host defense response (GO:0052031) | 4.13901769 |
| 36 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.13901769 |
| 37 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.13901769 |
| 38 | negative regulation of leukocyte mediated immunity (GO:0002704) | 4.09034531 |
| 39 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.08624678 |
| 40 | positive regulation of tolerance induction (GO:0002645) | 4.04789188 |
| 41 | regulation of tolerance induction (GO:0002643) | 4.03883857 |
| 42 | regulation of B cell differentiation (GO:0045577) | 3.97888710 |
| 43 | positive regulation of granulocyte differentiation (GO:0030854) | 3.90433311 |
| 44 | positive regulation of B cell differentiation (GO:0045579) | 3.89688038 |
| 45 | interferon-gamma production (GO:0032609) | 3.84182197 |
| 46 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.83639059 |
| 47 | detection of other organism (GO:0098543) | 3.81006288 |
| 48 | detection of bacterium (GO:0016045) | 3.80346051 |
| 49 | negative regulation of interleukin-12 production (GO:0032695) | 3.72682365 |
| 50 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.65852627 |
| 51 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.59979764 |
| 52 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.59483586 |
| 53 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.57808440 |
| 54 | T cell receptor signaling pathway (GO:0050852) | 3.57750542 |
| 55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.55076520 |
| 56 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.54684087 |
| 57 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.54602430 |
| 58 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.53164730 |
| 59 | neutrophil activation involved in immune response (GO:0002283) | 3.52449522 |
| 60 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.51718762 |
| 61 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.51535596 |
| 62 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.51496949 |
| 63 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.48069311 |
| 64 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.48017175 |
| 65 | T cell homeostasis (GO:0043029) | 3.47610340 |
| 66 | cellular response to type I interferon (GO:0071357) | 3.47176520 |
| 67 | type I interferon signaling pathway (GO:0060337) | 3.47176520 |
| 68 | response to type I interferon (GO:0034340) | 3.43840250 |
| 69 | cellular extravasation (GO:0045123) | 3.43597685 |
| 70 | B cell receptor signaling pathway (GO:0050853) | 3.39558460 |
| 71 | negative regulation of adaptive immune response (GO:0002820) | 3.39125164 |
| 72 | dendritic cell chemotaxis (GO:0002407) | 3.35729279 |
| 73 | regulation of cell killing (GO:0031341) | 3.28919999 |
| 74 | mast cell activation (GO:0045576) | 3.28199387 |
| 75 | positive regulation of humoral immune response (GO:0002922) | 3.21022578 |
| 76 | positive regulation of cell killing (GO:0031343) | 3.20662657 |
| 77 | dendritic cell migration (GO:0036336) | 3.19241529 |
| 78 | alpha-beta T cell differentiation (GO:0046632) | 3.14934782 |
| 79 | regulation of isotype switching (GO:0045191) | 3.13889487 |
| 80 | respiratory burst (GO:0045730) | 3.09647517 |
| 81 | neutrophil activation (GO:0042119) | 3.07743402 |
| 82 | macrophage activation involved in immune response (GO:0002281) | 3.07613158 |
| 83 | positive regulation of isotype switching (GO:0045830) | 3.07607882 |
| 84 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.06096995 |
| 85 | negative regulation of B cell mediated immunity (GO:0002713) | 3.06091265 |
| 86 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.06091265 |
| 87 | NIK/NF-kappaB signaling (GO:0038061) | 3.01723368 |
| 88 | regulation of T cell mediated immunity (GO:0002709) | 3.00433751 |
| 89 | negative regulation of type 2 immune response (GO:0002829) | 2.99126104 |
| 90 | positive regulation of interleukin-2 production (GO:0032743) | 2.97050136 |
| 91 | detection of external biotic stimulus (GO:0098581) | 2.93731825 |
| 92 | alpha-beta T cell activation (GO:0046631) | 2.92349862 |
| 93 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.91925453 |
| 94 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.91925453 |
| 95 | positive regulation of B cell mediated immunity (GO:0002714) | 2.91921630 |
| 96 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.91921630 |
| 97 | leukocyte degranulation (GO:0043299) | 2.91148808 |
| 98 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.89405790 |
| 99 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.88673363 |
| 100 | lymphocyte migration (GO:0072676) | 2.88430649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.47733447 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.46169740 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.16494990 |
| 4 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.81034620 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.71744565 |
| 6 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.62834615 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.62597741 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.43325397 |
| 9 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.35278263 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 3.35191594 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.28877808 |
| 12 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.01641388 |
| 13 | MAF_26560356_Chip-Seq_TH1_Human | 2.97426171 |
| 14 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.93652356 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.88564713 |
| 16 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.76693594 |
| 17 | MYB_26560356_Chip-Seq_TH1_Human | 2.73722257 |
| 18 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.56370013 |
| 19 | UTX_26944678_Chip-Seq_JUKART_Human | 2.54650120 |
| 20 | MYC_22102868_ChIP-Seq_BL_Human | 2.52557486 |
| 21 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.47817456 |
| 22 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.43486950 |
| 23 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.43469685 |
| 24 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.31797012 |
| 25 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.31213704 |
| 26 | MAF_26560356_Chip-Seq_TH2_Human | 2.17190529 |
| 27 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.13490874 |
| 28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.10875950 |
| 29 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.06333912 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.05430116 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.05167727 |
| 32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.00980811 |
| 33 | SPI1_23127762_ChIP-Seq_K562_Human | 1.99278444 |
| 34 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.91006508 |
| 35 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.90078694 |
| 36 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.89355458 |
| 37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.84480592 |
| 38 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.82090447 |
| 39 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.81906267 |
| 40 | GATA3_26560356_Chip-Seq_TH2_Human | 1.79237863 |
| 41 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.78487230 |
| 42 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.75399094 |
| 43 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.74464303 |
| 44 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72176129 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65956369 |
| 46 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.65448474 |
| 47 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.56637380 |
| 48 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.53574719 |
| 49 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.53092865 |
| 50 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.52076136 |
| 51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.46293316 |
| 52 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.44674625 |
| 53 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.44302653 |
| 54 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.35079668 |
| 55 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.34167481 |
| 56 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.32596337 |
| 57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.31216004 |
| 58 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.27875932 |
| 59 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27853352 |
| 60 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.24738218 |
| 61 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24011866 |
| 62 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23587938 |
| 63 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.23141736 |
| 64 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.22058926 |
| 65 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.16652303 |
| 66 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.15802887 |
| 67 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.15335815 |
| 68 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.15121290 |
| 69 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.14009552 |
| 70 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12974933 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.10020076 |
| 72 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.09680980 |
| 73 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.08514592 |
| 74 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07872367 |
| 75 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06064299 |
| 76 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02841920 |
| 77 | GATA1_22025678_ChIP-Seq_K562_Human | 1.00644631 |
| 78 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.98822383 |
| 79 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.97973036 |
| 80 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.97575294 |
| 81 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.95277503 |
| 82 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.93568540 |
| 83 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.92392924 |
| 84 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90079495 |
| 85 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.89525203 |
| 86 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89459091 |
| 87 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.86993141 |
| 88 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86913662 |
| 89 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.86677353 |
| 90 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.82336433 |
| 91 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.79375142 |
| 92 | GATA1_19941826_ChIP-Seq_K562_Human | 0.78535819 |
| 93 | GATA3_26560356_Chip-Seq_TH1_Human | 0.78012465 |
| 94 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.77511043 |
| 95 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76831181 |
| 96 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.76435044 |
| 97 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.75679482 |
| 98 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75634306 |
| 99 | GATA2_19941826_ChIP-Seq_K562_Human | 0.73846349 |
| 100 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.71209336 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.48304849 |
| 2 | MP0005671_abnormal_response_to | 4.25497060 |
| 3 | MP0003436_decreased_susceptibility_to | 4.19961571 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.97609645 |
| 5 | MP0003724_increased_susceptibility_to | 3.55878399 |
| 6 | MP0001800_abnormal_humoral_immune | 3.36894217 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.17857565 |
| 8 | MP0005387_immune_system_phenotype | 2.94028789 |
| 9 | MP0001790_abnormal_immune_system | 2.94028789 |
| 10 | MP0000685_abnormal_immune_system | 2.92620432 |
| 11 | MP0009785_altered_susceptibility_to | 2.88737871 |
| 12 | MP0009333_abnormal_splenocyte_physiolog | 2.87472655 |
| 13 | MP0002723_abnormal_immune_serum | 2.83916549 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.79014075 |
| 15 | MP0005025_abnormal_response_to | 2.78283079 |
| 16 | MP0001819_abnormal_immune_cell | 2.74384405 |
| 17 | MP0003303_peritoneal_inflammation | 2.61146740 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.59932507 |
| 19 | MP0002419_abnormal_innate_immunity | 2.54907780 |
| 20 | MP0002405_respiratory_system_inflammati | 2.50446056 |
| 21 | MP0006082_CNS_inflammation | 2.47351879 |
| 22 | MP0002398_abnormal_bone_marrow | 2.47084714 |
| 23 | MP0003300_gastrointestinal_ulcer | 2.44021336 |
| 24 | MP0000703_abnormal_thymus_morphology | 2.38794918 |
| 25 | MP0003866_abnormal_defecation | 2.32220627 |
| 26 | MP0002148_abnormal_hypersensitivity_rea | 2.30931296 |
| 27 | MP0000716_abnormal_immune_system | 2.24496087 |
| 28 | MP0004381_abnormal_hair_follicle | 2.22383933 |
| 29 | MP0001873_stomach_inflammation | 2.12311385 |
| 30 | MP0010155_abnormal_intestine_physiology | 2.11413321 |
| 31 | MP0000689_abnormal_spleen_morphology | 2.00981724 |
| 32 | MP0002722_abnormal_immune_system | 1.97416853 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.84666465 |
| 34 | MP0001533_abnormal_skeleton_physiology | 1.81944689 |
| 35 | MP0004947_skin_inflammation | 1.79398496 |
| 36 | MP0002429_abnormal_blood_cell | 1.76206943 |
| 37 | MP0002166_altered_tumor_susceptibility | 1.74035472 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.72823537 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.71599467 |
| 40 | MP0002396_abnormal_hematopoietic_system | 1.61251863 |
| 41 | MP0005310_abnormal_salivary_gland | 1.60119280 |
| 42 | MP0000465_gastrointestinal_hemorrhage | 1.57488686 |
| 43 | MP0002132_abnormal_respiratory_system | 1.41770197 |
| 44 | MP0001851_eye_inflammation | 1.41083001 |
| 45 | MP0008469_abnormal_protein_level | 1.25919342 |
| 46 | MP0001853_heart_inflammation | 1.25085202 |
| 47 | MP0005075_abnormal_melanosome_morpholog | 1.25059167 |
| 48 | MP0008260_abnormal_autophagy | 1.17495402 |
| 49 | MP0003828_pulmonary_edema | 1.17036098 |
| 50 | MP0001348_abnormal_lacrimal_gland | 1.12415436 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.12091244 |
| 52 | MP0002006_tumorigenesis | 1.10982267 |
| 53 | MP0008057_abnormal_DNA_replication | 1.07702230 |
| 54 | MP0000858_altered_metastatic_potential | 1.05029273 |
| 55 | MP0009764_decreased_sensitivity_to | 1.04068379 |
| 56 | MP0003172_abnormal_lysosome_physiology | 1.03181601 |
| 57 | MP0004883_abnormal_blood_vessel | 1.02349986 |
| 58 | MP0003045_fibrosis | 1.01540789 |
| 59 | MP0000490_abnormal_crypts_of | 1.00899006 |
| 60 | MP0004808_abnormal_hematopoietic_stem | 0.99468539 |
| 61 | MP0002163_abnormal_gland_morphology | 0.99054211 |
| 62 | MP0002998_abnormal_bone_remodeling | 0.98707161 |
| 63 | MP0004510_myositis | 0.93526407 |
| 64 | MP0002138_abnormal_hepatobiliary_system | 0.93185941 |
| 65 | MP0002933_joint_inflammation | 0.92404274 |
| 66 | MP0002009_preneoplasia | 0.91953263 |
| 67 | MP0001663_abnormal_digestive_system | 0.90839814 |
| 68 | MP0009763_increased_sensitivity_to | 0.81124284 |
| 69 | MP0005451_abnormal_body_composition | 0.80156577 |
| 70 | MP0009278_abnormal_bone_marrow | 0.79655927 |
| 71 | MP0005390_skeleton_phenotype | 0.74444394 |
| 72 | MP0003448_altered_tumor_morphology | 0.74103453 |
| 73 | MP0002019_abnormal_tumor_incidence | 0.71044088 |
| 74 | MP0005166_decreased_susceptibility_to | 0.67475561 |
| 75 | MP0003795_abnormal_bone_structure | 0.65551296 |
| 76 | MP0000015_abnormal_ear_pigmentation | 0.62056732 |
| 77 | MP0005164_abnormal_response_to | 0.60192105 |
| 78 | MP0005397_hematopoietic_system_phenotyp | 0.59380837 |
| 79 | MP0001545_abnormal_hematopoietic_system | 0.59380837 |
| 80 | MP0003690_abnormal_glial_cell | 0.57922509 |
| 81 | MP0001986_abnormal_taste_sensitivity | 0.57805136 |
| 82 | MP0002693_abnormal_pancreas_physiology | 0.57676897 |
| 83 | MP0000604_amyloidosis | 0.57570569 |
| 84 | MP0004130_abnormal_muscle_cell | 0.56123608 |
| 85 | MP0003221_abnormal_cardiomyocyte_apopto | 0.55656012 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.53581527 |
| 87 | MP0003183_abnormal_peptide_metabolism | 0.53182143 |
| 88 | MP0000249_abnormal_blood_vessel | 0.50918668 |
| 89 | MP0003091_abnormal_cell_migration | 0.48511092 |
| 90 | MP0003075_altered_response_to | 0.48063840 |
| 91 | MP0005381_digestive/alimentary_phenotyp | 0.45231783 |
| 92 | MP0008961_abnormal_basal_metabolism | 0.43576096 |
| 93 | MP0000609_abnormal_liver_physiology | 0.41221293 |
| 94 | MP0003806_abnormal_nucleotide_metabolis | 0.39150126 |
| 95 | MP0008873_increased_physiological_sensi | 0.38354086 |
| 96 | MP0008874_decreased_physiological_sensi | 0.37328171 |
| 97 | MP0004142_abnormal_muscle_tone | 0.36344064 |
| 98 | MP0005379_endocrine/exocrine_gland_phen | 0.35639121 |
| 99 | MP0001765_abnormal_ion_homeostasis | 0.35519607 |
| 100 | MP0001919_abnormal_reproductive_system | 0.35183027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.62925507 |
| 2 | T lymphocytopenia (HP:0005403) | 6.30061666 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.13903181 |
| 4 | Abnormality of T cell number (HP:0011839) | 5.91293526 |
| 5 | Eczematoid dermatitis (HP:0000976) | 5.87914900 |
| 6 | Myositis (HP:0100614) | 5.29717116 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 4.79324506 |
| 8 | Recurrent abscess formation (HP:0002722) | 4.74664007 |
| 9 | Orchitis (HP:0100796) | 4.69581138 |
| 10 | Retrobulbar optic neuritis (HP:0100654) | 4.64454420 |
| 11 | Optic neuritis (HP:0100653) | 4.64454420 |
| 12 | Abnormality of T cells (HP:0002843) | 4.58174304 |
| 13 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.45333152 |
| 14 | Recurrent fungal infections (HP:0002841) | 4.38749432 |
| 15 | Abnormality of macrophages (HP:0004311) | 4.25140592 |
| 16 | Gastrointestinal infarctions (HP:0005244) | 4.21822333 |
| 17 | Autoimmune hemolytic anemia (HP:0001890) | 4.15430344 |
| 18 | Meningitis (HP:0001287) | 3.85857506 |
| 19 | Increased IgM level (HP:0003496) | 3.84992091 |
| 20 | Severe combined immunodeficiency (HP:0004430) | 3.83661420 |
| 21 | Encephalitis (HP:0002383) | 3.82647032 |
| 22 | Mediastinal lymphadenopathy (HP:0100721) | 3.78784243 |
| 23 | Recurrent cutaneous fungal infections (HP:0011370) | 3.76640178 |
| 24 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.76640178 |
| 25 | Obstructive lung disease (HP:0006536) | 3.67076124 |
| 26 | Chronic obstructive pulmonary disease (HP:0006510) | 3.67076124 |
| 27 | Spontaneous hematomas (HP:0007420) | 3.66281399 |
| 28 | Vasculitis (HP:0002633) | 3.56814130 |
| 29 | Recurrent skin infections (HP:0001581) | 3.55406561 |
| 30 | Hypochromic microcytic anemia (HP:0004840) | 3.51361200 |
| 31 | Pulmonary infiltrates (HP:0002113) | 3.50737124 |
| 32 | Leukocytosis (HP:0001974) | 3.44537810 |
| 33 | Keratoconjunctivitis sicca (HP:0001097) | 3.42640588 |
| 34 | Recurrent bronchitis (HP:0002837) | 3.37658755 |
| 35 | Recurrent viral infections (HP:0004429) | 3.35300236 |
| 36 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.35007239 |
| 37 | Abnormality of eosinophils (HP:0001879) | 3.25959632 |
| 38 | IgG deficiency (HP:0004315) | 3.25227132 |
| 39 | Abnormality of T cell physiology (HP:0011840) | 3.25040920 |
| 40 | Keratoconjunctivitis (HP:0001096) | 3.24785109 |
| 41 | Pustule (HP:0200039) | 3.24128963 |
| 42 | Hypochromic anemia (HP:0001931) | 3.21782948 |
| 43 | Chest pain (HP:0100749) | 3.21270633 |
| 44 | Increased IgE level (HP:0003212) | 3.10418179 |
| 45 | Panhypogammaglobulinemia (HP:0003139) | 3.08825635 |
| 46 | Gingivitis (HP:0000230) | 3.03485146 |
| 47 | Prolonged bleeding time (HP:0003010) | 3.03189935 |
| 48 | Combined immunodeficiency (HP:0005387) | 3.01611651 |
| 49 | Granulocytopenia (HP:0001913) | 3.01463968 |
| 50 | Hemoptysis (HP:0002105) | 2.94259368 |
| 51 | Lymphopenia (HP:0001888) | 2.92881789 |
| 52 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.83175765 |
| 53 | Eosinophilia (HP:0001880) | 2.82546209 |
| 54 | IgM deficiency (HP:0002850) | 2.77967648 |
| 55 | Chronic diarrhea (HP:0002028) | 2.77189461 |
| 56 | Anorexia (HP:0002039) | 2.74035625 |
| 57 | Urticaria (HP:0001025) | 2.72821062 |
| 58 | Inflammation of the large intestine (HP:0002037) | 2.66785274 |
| 59 | Pulmonary embolism (HP:0002204) | 2.66006540 |
| 60 | Microcytic anemia (HP:0001935) | 2.65670200 |
| 61 | Chronic otitis media (HP:0000389) | 2.64805115 |
| 62 | Epistaxis (HP:0000421) | 2.64752655 |
| 63 | Hypergammaglobulinemia (HP:0010702) | 2.61944702 |
| 64 | Gastrointestinal inflammation (HP:0004386) | 2.59596434 |
| 65 | Gingival bleeding (HP:0000225) | 2.58583041 |
| 66 | Arterial thrombosis (HP:0004420) | 2.57247202 |
| 67 | Nasal polyposis (HP:0100582) | 2.50450369 |
| 68 | Gangrene (HP:0100758) | 2.49118124 |
| 69 | Agammaglobulinemia (HP:0004432) | 2.45959972 |
| 70 | Thyroiditis (HP:0100646) | 2.45397905 |
| 71 | Joint swelling (HP:0001386) | 2.43123924 |
| 72 | Episodic fever (HP:0001954) | 2.33721211 |
| 73 | Papilledema (HP:0001085) | 2.33546521 |
| 74 | Cellulitis (HP:0100658) | 2.32577404 |
| 75 | Abnormality of the fingertips (HP:0001211) | 2.32315180 |
| 76 | Sepsis (HP:0100806) | 2.30884479 |
| 77 | Lymphoma (HP:0002665) | 2.27842260 |
| 78 | Abnormality of the pleura (HP:0002103) | 2.27181776 |
| 79 | Petechiae (HP:0000967) | 2.24462140 |
| 80 | Verrucae (HP:0200043) | 2.19822032 |
| 81 | Papilloma (HP:0012740) | 2.19822032 |
| 82 | Acute hepatic failure (HP:0006554) | 2.16871935 |
| 83 | Slow saccadic eye movements (HP:0000514) | 2.16298952 |
| 84 | Glomerulopathy (HP:0100820) | 2.15701305 |
| 85 | Hypoplasia of the thymus (HP:0000778) | 2.15222220 |
| 86 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.09856499 |
| 87 | Osteomyelitis (HP:0002754) | 2.05136449 |
| 88 | Keratitis (HP:0000491) | 2.02698106 |
| 89 | Bronchitis (HP:0012387) | 2.02287981 |
| 90 | Skin ulcer (HP:0200042) | 2.01584002 |
| 91 | Colitis (HP:0002583) | 2.01410898 |
| 92 | Abnormality of the nasal mucosa (HP:0000433) | 1.99840229 |
| 93 | Polyneuropathy (HP:0001271) | 1.98295517 |
| 94 | Fatigue (HP:0012378) | 1.96423316 |
| 95 | Basal cell carcinoma (HP:0002671) | 1.91989543 |
| 96 | Autoimmune thrombocytopenia (HP:0001973) | 1.88876393 |
| 97 | Skin rash (HP:0000988) | 1.88036954 |
| 98 | Abnormal platelet volume (HP:0011876) | 1.87997926 |
| 99 | Amaurosis fugax (HP:0100576) | 1.83495284 |
| 100 | Abnormality of the pericardium (HP:0001697) | 1.79863469 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 4.74124711 |
| 2 | TXK | 4.09992365 |
| 3 | RIPK4 | 3.75206569 |
| 4 | FES | 2.90144942 |
| 5 | TYK2 | 2.72413225 |
| 6 | CSK | 2.61116841 |
| 7 | ITK | 2.30430564 |
| 8 | BTK | 2.25325255 |
| 9 | JAK3 | 2.20244454 |
| 10 | ZAP70 | 2.18704706 |
| 11 | TAOK3 | 2.18554335 |
| 12 | SIK3 | 2.16814922 |
| 13 | PRPF4B | 2.11421833 |
| 14 | MAP2K3 | 2.08231654 |
| 15 | JAK1 | 2.06293743 |
| 16 | GRK6 | 2.03987338 |
| 17 | IRAK4 | 1.93380723 |
| 18 | TEC | 1.82242469 |
| 19 | EPHB1 | 1.80784045 |
| 20 | HCK | 1.76845476 |
| 21 | IKBKE | 1.71188846 |
| 22 | BLK | 1.67739451 |
| 23 | TNK2 | 1.67736821 |
| 24 | SYK | 1.66723274 |
| 25 | LCK | 1.64517556 |
| 26 | MAP3K13 | 1.61513911 |
| 27 | FGFR4 | 1.55412417 |
| 28 | MAP3K14 | 1.55380405 |
| 29 | TAOK1 | 1.46006003 |
| 30 | STK10 | 1.45694798 |
| 31 | NLK | 1.44089884 |
| 32 | MAP3K3 | 1.36063510 |
| 33 | MARK3 | 1.35483459 |
| 34 | ERN1 | 1.32966835 |
| 35 | CAMKK2 | 1.32666818 |
| 36 | JAK2 | 1.29437781 |
| 37 | LYN | 1.27659795 |
| 38 | FGFR3 | 1.18307084 |
| 39 | SIK2 | 1.09604709 |
| 40 | PASK | 1.09530905 |
| 41 | IKBKB | 1.09141657 |
| 42 | MAP3K11 | 1.07914605 |
| 43 | HIPK2 | 1.05788454 |
| 44 | KSR2 | 1.03561570 |
| 45 | FGR | 0.99841414 |
| 46 | CAMKK1 | 0.98669985 |
| 47 | MAP3K1 | 0.97972613 |
| 48 | PRKCQ | 0.93662071 |
| 49 | TBK1 | 0.92804567 |
| 50 | LRRK2 | 0.90997300 |
| 51 | TYRO3 | 0.90798725 |
| 52 | MST4 | 0.90102355 |
| 53 | YES1 | 0.89510302 |
| 54 | CSF1R | 0.88077751 |
| 55 | PDK1 | 0.85965451 |
| 56 | EPHA3 | 0.83945176 |
| 57 | TAOK2 | 0.83659090 |
| 58 | MARK2 | 0.79809091 |
| 59 | BMPR2 | 0.77898469 |
| 60 | PIK3CG | 0.74926594 |
| 61 | MAP3K10 | 0.68209100 |
| 62 | PIM1 | 0.67950081 |
| 63 | GRK7 | 0.66905962 |
| 64 | STK38 | 0.65236001 |
| 65 | FYN | 0.63205606 |
| 66 | CDK4 | 0.63139143 |
| 67 | KIT | 0.63024510 |
| 68 | MAPK12 | 0.60850991 |
| 69 | MAPK11 | 0.60826025 |
| 70 | DYRK1B | 0.60492245 |
| 71 | MAP3K7 | 0.59884111 |
| 72 | PTK6 | 0.58316816 |
| 73 | IRAK1 | 0.56757368 |
| 74 | TGFBR2 | 0.56193996 |
| 75 | CDK19 | 0.55466331 |
| 76 | SIK1 | 0.53726536 |
| 77 | NEK6 | 0.51411008 |
| 78 | CHUK | 0.50451121 |
| 79 | RAF1 | 0.50240422 |
| 80 | SMG1 | 0.49815710 |
| 81 | MAP3K5 | 0.47812318 |
| 82 | PDGFRB | 0.46260170 |
| 83 | MAP3K2 | 0.45855962 |
| 84 | STK4 | 0.41331493 |
| 85 | PRKD2 | 0.40645044 |
| 86 | BRD4 | 0.39855771 |
| 87 | PRKCH | 0.39805028 |
| 88 | CDK12 | 0.39790225 |
| 89 | KSR1 | 0.39377610 |
| 90 | PDPK1 | 0.38861254 |
| 91 | STK11 | 0.38032441 |
| 92 | MAPK7 | 0.37998960 |
| 93 | TRIB3 | 0.37463490 |
| 94 | SGK3 | 0.34538796 |
| 95 | MAP3K8 | 0.34246185 |
| 96 | MAP2K6 | 0.32720366 |
| 97 | RET | 0.32145411 |
| 98 | MAP3K12 | 0.31972477 |
| 99 | CDK6 | 0.30454098 |
| 100 | CLK1 | 0.29731621 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.23009755 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.12216237 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.98815798 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.78203913 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.74873153 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.69214335 |
| 7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.51604294 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.50086056 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.23093761 |
| 10 | Leishmaniasis_Homo sapiens_hsa05140 | 2.19120223 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.12571496 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.08648896 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.98812889 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.96647463 |
| 15 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.92848258 |
| 16 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.90120107 |
| 17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.79854020 |
| 18 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.76374557 |
| 19 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.74520045 |
| 20 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.70280135 |
| 21 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.68218659 |
| 22 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.67006890 |
| 23 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.63589941 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.62948630 |
| 25 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.62397369 |
| 26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.61353416 |
| 27 | Malaria_Homo sapiens_hsa05144 | 1.60207433 |
| 28 | Tuberculosis_Homo sapiens_hsa05152 | 1.51564476 |
| 29 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.45494580 |
| 30 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.40723966 |
| 31 | Hepatitis B_Homo sapiens_hsa05161 | 1.36767255 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.33036223 |
| 33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.30683196 |
| 34 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.30543816 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.28496245 |
| 36 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.25773161 |
| 37 | Legionellosis_Homo sapiens_hsa05134 | 1.23030252 |
| 38 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.20668101 |
| 39 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.18862736 |
| 40 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.11462786 |
| 41 | Platelet activation_Homo sapiens_hsa04611 | 1.10299609 |
| 42 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.09882976 |
| 43 | Asthma_Homo sapiens_hsa05310 | 1.08688196 |
| 44 | Hepatitis C_Homo sapiens_hsa05160 | 1.05556683 |
| 45 | Apoptosis_Homo sapiens_hsa04210 | 1.03913994 |
| 46 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.03639643 |
| 47 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.99101680 |
| 48 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.98384942 |
| 49 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.97737788 |
| 50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.93676749 |
| 51 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.93398523 |
| 52 | Shigellosis_Homo sapiens_hsa05131 | 0.92623680 |
| 53 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.92182301 |
| 54 | HTLV-I infection_Homo sapiens_hsa05166 | 0.87311386 |
| 55 | Colorectal cancer_Homo sapiens_hsa05210 | 0.83759621 |
| 56 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.80991092 |
| 57 | Endometrial cancer_Homo sapiens_hsa05213 | 0.78213040 |
| 58 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.77252512 |
| 59 | Endocytosis_Homo sapiens_hsa04144 | 0.74825274 |
| 60 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.73949225 |
| 61 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.70790260 |
| 62 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.68600289 |
| 63 | Phagosome_Homo sapiens_hsa04145 | 0.67502703 |
| 64 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.65818567 |
| 65 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64399334 |
| 66 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.64271546 |
| 67 | Pertussis_Homo sapiens_hsa05133 | 0.57915839 |
| 68 | Salmonella infection_Homo sapiens_hsa05132 | 0.57844874 |
| 69 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.57401442 |
| 70 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.57250900 |
| 71 | Thyroid cancer_Homo sapiens_hsa05216 | 0.57101761 |
| 72 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.56596355 |
| 73 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.56574102 |
| 74 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.55820083 |
| 75 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.55181369 |
| 76 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.54166418 |
| 77 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.49859869 |
| 78 | Prostate cancer_Homo sapiens_hsa05215 | 0.48192346 |
| 79 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.47145348 |
| 80 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.46914911 |
| 81 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.45763890 |
| 82 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.45693212 |
| 83 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.45569735 |
| 84 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44521089 |
| 85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.43980255 |
| 86 | Insulin resistance_Homo sapiens_hsa04931 | 0.43310395 |
| 87 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.43094064 |
| 88 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.41285778 |
| 89 | Long-term potentiation_Homo sapiens_hsa04720 | 0.39344047 |
| 90 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.37954477 |
| 91 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.34859630 |
| 92 | Glioma_Homo sapiens_hsa05214 | 0.34816365 |
| 93 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.34638970 |
| 94 | Other glycan degradation_Homo sapiens_hsa00511 | 0.33154362 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.32973914 |
| 96 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.30517282 |
| 97 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.29786158 |
| 98 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.27839031 |
| 99 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.24786154 |
| 100 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.24698919 |

