TRAV10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)9.14468802
2negative thymic T cell selection (GO:0045060)9.07902841
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G8.78869616
4positive thymic T cell selection (GO:0045059)8.58214387
5T cell migration (GO:0072678)8.11019105
6leukocyte aggregation (GO:0070486)8.08478507
7positive regulation of gamma-delta T cell activation (GO:0046645)7.94898612
8positive T cell selection (GO:0043368)7.57473922
9thymic T cell selection (GO:0045061)7.21528961
10positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)7.19895877
11regulation of gamma-delta T cell differentiation (GO:0045586)7.10282027
12sequestering of actin monomers (GO:0042989)6.68155278
13T cell selection (GO:0045058)6.48366874
14negative regulation of T cell mediated immunity (GO:0002710)6.41854629
15regulation of gamma-delta T cell activation (GO:0046643)6.26706062
16positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.23066203
17cellular response to interleukin-15 (GO:0071350)6.21301983
18antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.07568123
19antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.07568123
20interferon-gamma production (GO:0032609)6.00788212
21regulation of isotype switching to IgG isotypes (GO:0048302)5.97366406
22negative regulation of cell killing (GO:0031342)5.96585527
23negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.96585527
24response to interleukin-15 (GO:0070672)5.88883280
25T cell costimulation (GO:0031295)5.74127177
26T cell receptor signaling pathway (GO:0050852)5.69884231
27lymphocyte costimulation (GO:0031294)5.62993333
28regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)5.40989524
29interleukin-6-mediated signaling pathway (GO:0070102)5.36691152
30negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)5.34849638
31alpha-beta T cell activation (GO:0046631)5.20916537
32positive regulation of alpha-beta T cell proliferation (GO:0046641)5.13530612
33antigen processing and presentation of endogenous antigen (GO:0019883)4.97111777
34regulation of T cell receptor signaling pathway (GO:0050856)4.95458164
35regulation of alpha-beta T cell proliferation (GO:0046640)4.93096613
36positive regulation of T cell mediated cytotoxicity (GO:0001916)4.91214453
37daunorubicin metabolic process (GO:0044597)4.85035127
38polyketide metabolic process (GO:0030638)4.85035127
39doxorubicin metabolic process (GO:0044598)4.85035127
40regulation of T cell tolerance induction (GO:0002664)4.74358574
41T-helper cell differentiation (GO:0042093)4.68713120
42CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)4.68713120
43Peyers patch development (GO:0048541)4.65850157
44mucosal-associated lymphoid tissue development (GO:0048537)4.65850157
45antigen receptor-mediated signaling pathway (GO:0050851)4.65476246
46positive regulation of T-helper 1 type immune response (GO:0002827)4.64968266
47positive regulation of T cell cytokine production (GO:0002726)4.63624764
48regulation of interleukin-2 biosynthetic process (GO:0045076)4.61582199
49regulation of T cell mediated cytotoxicity (GO:0001914)4.55638971
50negative regulation of execution phase of apoptosis (GO:1900118)4.54512935
51positive regulation of interleukin-2 production (GO:0032743)4.42200485
52cellular response to interleukin-4 (GO:0071353)4.39719593
53regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.37558945
54lymphocyte migration (GO:0072676)4.29887742
55regulation of regulatory T cell differentiation (GO:0045589)4.29305616
56positive regulation of T cell chemotaxis (GO:0010820)4.27180209
57regulation of T cell chemotaxis (GO:0010819)4.27180209
58positive regulation of transforming growth factor beta production (GO:0071636)4.27042815
59histone H3-K4 trimethylation (GO:0080182)4.21883627
60T cell differentiation involved in immune response (GO:0002292)4.14457558
61alpha-beta T cell differentiation involved in immune response (GO:0002293)4.14457558
62alpha-beta T cell activation involved in immune response (GO:0002287)4.14457558
63regulation of B cell receptor signaling pathway (GO:0050855)4.12149249
64regulation of immunoglobulin secretion (GO:0051023)4.11752689
65B cell proliferation (GO:0042100)3.96299027
66positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.91829724
67positive regulation of type 2 immune response (GO:0002830)3.89669780
68positive regulation of humoral immune response (GO:0002922)3.88471553
69tolerance induction (GO:0002507)3.87596444
70activated T cell proliferation (GO:0050798)3.83576033
71regulation of T cell cytokine production (GO:0002724)3.82900795
72positive regulation of tolerance induction (GO:0002645)3.82148149
73positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.79273300
74response to interleukin-4 (GO:0070670)3.79016627
75regulation of T-helper 1 type immune response (GO:0002825)3.74427934
76CD4-positive, alpha-beta T cell differentiation (GO:0043367)3.73930298
77positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.73559602
78negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.72477007
79natural killer cell differentiation (GO:0001779)3.71793248
80positive regulation of immunoglobulin mediated immune response (GO:0002891)3.70175254
81positive regulation of B cell mediated immunity (GO:0002714)3.70175254
82T cell differentiation (GO:0030217)3.69846791
83NIK/NF-kappaB signaling (GO:0038061)3.67324124
84negative regulation of cytokine production involved in immune response (GO:0002719)3.63310701
85mast cell activation (GO:0045576)3.62783065
86lymph node development (GO:0048535)3.61531667
87positive regulation of histone H3-K4 methylation (GO:0051571)3.59930943
88positive regulation of neutrophil chemotaxis (GO:0090023)3.59315524
89positive regulation of neutrophil migration (GO:1902624)3.59315524
90positive regulation of lamellipodium assembly (GO:0010592)3.58445620
91negative regulation of interleukin-2 production (GO:0032703)3.55628487
92regulation of leukocyte mediated cytotoxicity (GO:0001910)3.55294649
93negative regulation of B cell mediated immunity (GO:0002713)3.55174016
94negative regulation of immunoglobulin mediated immune response (GO:0002890)3.55174016
95T cell proliferation (GO:0042098)3.51826769
96CD4-positive, alpha-beta T cell activation (GO:0035710)3.51317937
97regulation of immunoglobulin production (GO:0002637)3.49102434
98regulation of respiratory burst (GO:0060263)3.48717306
99regulation of interleukin-12 biosynthetic process (GO:0045075)3.48149629
100negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.46774376
101positive regulation of immunoglobulin production (GO:0002639)3.43248465
102transcription elongation from RNA polymerase III promoter (GO:0006385)3.42958955
103termination of RNA polymerase III transcription (GO:0006386)3.42958955
104leukocyte cell-cell adhesion (GO:0007159)3.42317134
105positive regulation of cell killing (GO:0031343)3.42101294
106regulation of B cell differentiation (GO:0045577)3.40317676
107regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)3.39832291
108positive regulation of astrocyte differentiation (GO:0048711)3.38428735
109positive regulation of isotype switching (GO:0045830)3.38078825
110negative regulation of alpha-beta T cell activation (GO:0046636)3.38071034
111positive regulation of macrophage differentiation (GO:0045651)3.37332595
112positive regulation of uterine smooth muscle contraction (GO:0070474)3.33501542
113regulation of response to interferon-gamma (GO:0060330)3.31741983
114positive regulation of alpha-beta T cell activation (GO:0046635)3.31135562
115negative regulation of lymphocyte mediated immunity (GO:0002707)3.29984750
116regulation of defense response to virus by virus (GO:0050690)3.29631218
117negative regulation of T cell receptor signaling pathway (GO:0050860)3.28792441
118tumor necrosis factor-mediated signaling pathway (GO:0033209)3.28783529
119regulation of tolerance induction (GO:0002643)3.27122550
120regulation of isotype switching (GO:0045191)3.25419407
121positive regulation of T cell activation (GO:0050870)3.25092127
122negative regulation of adaptive immune response (GO:0002820)3.24112359
123regulation of cell killing (GO:0031341)3.22837350
124regulation of immunoglobulin mediated immune response (GO:0002889)3.22761583
125regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.22614955
126regulation of interleukin-2 production (GO:0032663)3.22499635
127regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.22365562
128regulation of interleukin-4 production (GO:0032673)3.21937571
129immune response-activating cell surface receptor signaling pathway (GO:0002429)3.19994103
130natural killer cell activation (GO:0030101)3.19283082
131positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.19205500
132positive regulation of natural killer cell mediated immunity (GO:0002717)3.19044591
133positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.19044591
134positive regulation of granulocyte differentiation (GO:0030854)3.18152365
135negative regulation of leukocyte mediated immunity (GO:0002704)3.17157219
136positive regulation of granulocyte chemotaxis (GO:0071624)3.16423452
137regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.15865753
138regulation of natural killer cell mediated immunity (GO:0002715)3.15865753
139DNA deamination (GO:0045006)3.15190350
140T cell homeostasis (GO:0043029)3.13545396
141positive regulation of T cell mediated immunity (GO:0002711)3.12821985
142positive regulation of calcium-mediated signaling (GO:0050850)3.10351930
143regulation of B cell mediated immunity (GO:0002712)3.10063973
144regulation of type I interferon-mediated signaling pathway (GO:0060338)3.09779577
145T cell activation (GO:0042110)3.09336608
146lymphocyte chemotaxis (GO:0048247)3.09217597
147alpha-beta T cell differentiation (GO:0046632)3.09081042
148aminoglycoside antibiotic metabolic process (GO:0030647)3.04606299
149regulation of alpha-beta T cell activation (GO:0046634)3.03757956

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.61819484
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.26468480
3RUNX_20019798_ChIP-Seq_JUKART_Human4.19078744
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.09979270
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.93495800
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.71878330
7STAT4_19710469_ChIP-ChIP_TH1__Mouse3.68177733
8IRF8_22096565_ChIP-ChIP_GC-B_Human3.65870286
9FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.45573813
10MYC_22102868_ChIP-Seq_BL_Human3.44051222
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.37523573
12ELF1_17652178_ChIP-ChIP_JURKAT_Human3.27938097
13UTX_26944678_Chip-Seq_JUKART_Human3.18554535
14MAF_26560356_Chip-Seq_TH1_Human2.96051259
15MYB_26560356_Chip-Seq_TH2_Human2.86635989
16VDR_22108803_ChIP-Seq_LS180_Human2.79165307
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.72751612
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.71960227
19MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.66756924
20MYB_26560356_Chip-Seq_TH1_Human2.59573569
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.53100882
22VDR_21846776_ChIP-Seq_THP-1_Human2.47499803
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.30991722
24RBPJ_22232070_ChIP-Seq_NCS_Mouse2.22950133
25MAF_26560356_Chip-Seq_TH2_Human2.17714263
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.16879065
27SCL_19346495_ChIP-Seq_HPC-7_Human2.12815248
28KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.09046238
29STAT6_21828071_ChIP-Seq_BEAS2B_Human2.08880140
30VDR_24763502_ChIP-Seq_THP-1_Human2.02373095
31NOTCH1_21737748_ChIP-Seq_TLL_Human1.99437570
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95091388
33GATA3_27048872_Chip-Seq_THYMUS_Human1.93393206
34BP1_19119308_ChIP-ChIP_Hs578T_Human1.88618171
35E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.86965596
36SMAD_19615063_ChIP-ChIP_OVARY_Human1.86841759
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.86229720
38TCF7_22412390_ChIP-Seq_EML_Mouse1.86117461
39KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.85572967
40RUNX1_22412390_ChIP-Seq_EML_Mouse1.84900505
41NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.79863700
42SPI1_23547873_ChIP-Seq_NB4_Human1.77914196
43CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.74458634
44VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73177810
45KDM2B_26808549_Chip-Seq_DND41_Human1.70677790
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.68567730
47JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.66231493
48SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.63716170
49EST1_17652178_ChIP-ChIP_JURKAT_Human1.62700130
50FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.61097150
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.58181178
52GABP_17652178_ChIP-ChIP_JURKAT_Human1.52566319
53MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.49690978
54RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.46419342
55FLI1_27457419_Chip-Seq_LIVER_Mouse1.45524366
56RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.43302269
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.40880568
58BRD4_27068464_Chip-Seq_AML-cells_Mouse1.38420138
59VDR_24787735_ChIP-Seq_THP-1_Human1.38381243
60KDM2B_26808549_Chip-Seq_JURKAT_Human1.34837834
61IRF8_21731497_ChIP-ChIP_J774_Mouse1.34517284
62PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34097291
63MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.31937864
64GATA2_22383799_ChIP-Seq_G1ME_Mouse1.29097674
65IRF8_27001747_Chip-Seq_BMDM_Mouse1.28296289
66PCGF2_27294783_Chip-Seq_ESCs_Mouse1.27989663
67SPI1_23127762_ChIP-Seq_K562_Human1.27665840
68ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26182994
69TFEB_21752829_ChIP-Seq_HELA_Human1.23984193
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.22495237
71VDR_23849224_ChIP-Seq_CD4+_Human1.22475885
72CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22317484
73BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.22301693
74CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.21381129
75FOXP3_21729870_ChIP-Seq_TREG_Human1.20966172
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.19647087
77ZNF274_21170338_ChIP-Seq_K562_Hela1.19349818
78KDM2B_26808549_Chip-Seq_SUP-B15_Human1.18342888
79SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human1.14672448
80LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13631274
81GATA3_26560356_Chip-Seq_TH1_Human1.12531328
82STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.11502890
83LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.05743936
84TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05685130
85NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02289033
86SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.01130757
87RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.00750299
88NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.00690053
89STAT1_20625510_ChIP-Seq_HELA_Human0.99041151
90EGR1_23403033_ChIP-Seq_LIVER_Mouse0.98721232
91MYB_21317192_ChIP-Seq_ERMYB_Mouse0.98485366
92ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97994344
93STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.97000985
94PU.1_20513432_ChIP-Seq_Bcells_Mouse0.95082089
95KDM5A_27292631_Chip-Seq_BREAST_Human0.94833337
96HOXB7_26014856_ChIP-Seq_BT474_Human0.94165056
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93211313
98PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92638851
99GATA1_19941826_ChIP-Seq_K562_Human0.91944857
100LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.91847947
101CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91663357
102HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.91180595
103GATA2_21666600_ChIP-Seq_HMVEC_Human0.90902931
104TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.90420358
105GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.90408914
106GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.86825660
107LXR_22292898_ChIP-Seq_THP-1_Human0.84214603
108MYC_19829295_ChIP-Seq_ESCs_Human0.83863788
109FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83708010
110DNAJC2_21179169_ChIP-ChIP_NT2_Human0.83260129
111PRDM14_20953172_ChIP-Seq_ESCs_Human0.83183698
112TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.82892540
113GATA3_26560356_Chip-Seq_TH2_Human0.82527962
114CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.82087474
115CIITA_25753668_ChIP-Seq_RAJI_Human0.81850601
116NFE2_27457419_Chip-Seq_LIVER_Mouse0.81010700
117GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80988967
118ELK1_19687146_ChIP-ChIP_HELA_Human0.80689513
119CTCF_26484167_Chip-Seq_Bcells_Mouse0.79107042
120SUZ12_27294783_Chip-Seq_NPCs_Mouse0.77849499
121RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76584887
122TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.75715025
123CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.75596472
124GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75559684
125PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.74406332
126SMRT_27268052_Chip-Seq_Bcells_Human0.73564752
127DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.73057295
128MYC_18555785_ChIP-Seq_MESCs_Mouse0.72447159
129FLI1_21867929_ChIP-Seq_CD8_Mouse0.72333296
130CEBPB_22108803_ChIP-Seq_LS180_Human0.72084545
131CTCF_20526341_ChIP-Seq_ESCs_Human0.71677769
132KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.70963122
133EZH2_27294783_Chip-Seq_NPCs_Mouse0.70485286
134GATA1_22025678_ChIP-Seq_K562_Human0.70214010
135FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.69593287
136HOXB4_20404135_ChIP-ChIP_EML_Mouse0.68998397
137SA1_27219007_Chip-Seq_ERYTHROID_Human0.68433697
138P300_27268052_Chip-Seq_Bcells_Human0.68424707
139PU_27001747_Chip-Seq_BMDM_Mouse0.68050174
140BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.68043063
141PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.67454511
142ETS1_20019798_ChIP-Seq_JURKAT_Human0.66954333

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.77521010
2MP0005671_abnormal_response_to5.17850345
3MP0003724_increased_susceptibility_to3.70266925
4MP0000685_abnormal_immune_system3.62606102
5MP0009785_altered_susceptibility_to3.58776472
6MP0002933_joint_inflammation3.27358801
7MP0008877_abnormal_DNA_methylation3.24476337
8MP0006082_CNS_inflammation3.04671222
9MP0003436_decreased_susceptibility_to3.02960801
10MP0004381_abnormal_hair_follicle2.90620311
11MP0009333_abnormal_splenocyte_physiolog2.87731682
12MP0005000_abnormal_immune_tolerance2.79803812
13MP0002420_abnormal_adaptive_immunity2.78411383
14MP0002405_respiratory_system_inflammati2.72972475
15MP0000703_abnormal_thymus_morphology2.72667845
16MP0001819_abnormal_immune_cell2.72567746
17MP0001800_abnormal_humoral_immune2.69918424
18MP0002398_abnormal_bone_marrow2.69200529
19MP0002723_abnormal_immune_serum2.65788149
20MP0005025_abnormal_response_to2.57390814
21MP0001835_abnormal_antigen_presentation2.43136192
22MP0003646_muscle_fatigue2.39257524
23MP0001790_abnormal_immune_system2.37016092
24MP0005387_immune_system_phenotype2.37016092
25MP0000716_abnormal_immune_system2.33890965
26MP0002148_abnormal_hypersensitivity_rea2.33754751
27MP0002166_altered_tumor_susceptibility2.31247422
28MP0002452_abnormal_antigen_presenting2.28416962
29MP0003866_abnormal_defecation2.19745468
30MP0002722_abnormal_immune_system2.17538593
31MP0003045_fibrosis2.14927671
32MP0000689_abnormal_spleen_morphology2.10310579
33MP0001873_stomach_inflammation1.90888046
34MP0002396_abnormal_hematopoietic_system1.90333312
35MP0005083_abnormal_biliary_tract1.84188450
36MP0002429_abnormal_blood_cell1.83358349
37MP0003172_abnormal_lysosome_physiology1.81014680
38MP0004510_myositis1.80822299
39MP0002006_tumorigenesis1.75048468
40MP0010155_abnormal_intestine_physiology1.71310877
41MP0002419_abnormal_innate_immunity1.62729443
42MP0004947_skin_inflammation1.60556865
43MP0003300_gastrointestinal_ulcer1.58723164
44MP0000613_abnormal_salivary_gland1.55588795
45MP0001845_abnormal_inflammatory_respons1.50158190
46MP0005451_abnormal_body_composition1.43994722
47MP0001243_abnormal_dermal_layer1.43719876
48MP0005084_abnormal_gallbladder_morpholo1.39776725
49MP0001533_abnormal_skeleton_physiology1.36230813
50MP0000604_amyloidosis1.34839043
51MP0004142_abnormal_muscle_tone1.33484575
52MP0005075_abnormal_melanosome_morpholog1.26511985
53MP0003303_peritoneal_inflammation1.25999012
54MP0005464_abnormal_platelet_physiology1.22970255
55MP0003329_amyloid_beta_deposits1.21410946
56MP0003448_altered_tumor_morphology1.20517105
57MP0008469_abnormal_protein_level1.18998987
58MP0008872_abnormal_physiological_respon1.17791515
59MP0009384_cardiac_valve_regurgitation1.16955554
60MP0000465_gastrointestinal_hemorrhage1.16661761
61MP0005076_abnormal_cell_differentiation1.15054831
62MP0001853_heart_inflammation1.12323460
63MP0009840_abnormal_foam_cell1.09966732
64MP0005310_abnormal_salivary_gland1.09778653
65MP0002277_abnormal_respiratory_mucosa1.08525324
66MP0002019_abnormal_tumor_incidence1.08364136
67MP0000490_abnormal_crypts_of1.04055539
68MP0004808_abnormal_hematopoietic_stem0.99717872
69MP0001501_abnormal_sleep_pattern0.99604200
70MP0003191_abnormal_cellular_cholesterol0.99184555
71MP0004742_abnormal_vestibular_system0.97712933
72MP0003221_abnormal_cardiomyocyte_apopto0.95720556
73MP0001764_abnormal_homeostasis0.92481770
74MP0009765_abnormal_xenobiotic_induced0.89096904
75MP0002132_abnormal_respiratory_system0.88921265
76MP0001851_eye_inflammation0.86719558
77MP0005023_abnormal_wound_healing0.86434973
78MP0005085_abnormal_gallbladder_physiolo0.86089234
79MP0005379_endocrine/exocrine_gland_phen0.85574810
80MP0000372_irregular_coat_pigmentation0.85544169
81MP0001663_abnormal_digestive_system0.84260780
82MP0009763_increased_sensitivity_to0.81094189
83MP0008007_abnormal_cellular_replicative0.79515778
84MP0004233_abnormal_muscle_weight0.77674471
85MP0000343_altered_response_to0.76720293
86MP0001346_abnormal_lacrimal_gland0.76137800
87MP0002138_abnormal_hepatobiliary_system0.75513321
88MP0002163_abnormal_gland_morphology0.75495467
89MP0000858_altered_metastatic_potential0.75059864
90MP0001661_extended_life_span0.74259632
91MP0004957_abnormal_blastocyst_morpholog0.72829649
92MP0000920_abnormal_myelination0.72088667
93MP0009764_decreased_sensitivity_to0.67289196
94MP0002009_preneoplasia0.65008547
95MP0000609_abnormal_liver_physiology0.64910849
96MP0005166_decreased_susceptibility_to0.64305701
97MP0003077_abnormal_cell_cycle0.62919606
98MP0001545_abnormal_hematopoietic_system0.62416424
99MP0005397_hematopoietic_system_phenotyp0.62416424
100MP0001348_abnormal_lacrimal_gland0.61374856
101MP0008875_abnormal_xenobiotic_pharmacok0.60908607
102MP0006035_abnormal_mitochondrial_morpho0.60784234
103MP0001765_abnormal_ion_homeostasis0.59744840
104MP0008057_abnormal_DNA_replication0.56955357
105MP0002998_abnormal_bone_remodeling0.56456311
106MP0002089_abnormal_postnatal_growth/wei0.54480334
107MP0000477_abnormal_intestine_morphology0.54478646
108MP0002136_abnormal_kidney_physiology0.54349922
109MP0008569_lethality_at_weaning0.50335726
110MP0003878_abnormal_ear_physiology0.49161132
111MP0005377_hearing/vestibular/ear_phenot0.49161132
112MP0002693_abnormal_pancreas_physiology0.45228425
113MP0002168_other_aberrant_phenotype0.44411575
114MP0001270_distended_abdomen0.44175352
115MP0003011_delayed_dark_adaptation0.43572165
116MP0003795_abnormal_bone_structure0.43441951
117MP0000750_abnormal_muscle_regeneration0.42552792
118MP0002083_premature_death0.42356351
119MP0001919_abnormal_reproductive_system0.41140941
120MP0003943_abnormal_hepatobiliary_system0.40108000
121MP0005330_cardiomyopathy0.39837365
122MP0001216_abnormal_epidermal_layer0.39611782
123MP0005390_skeleton_phenotype0.38819766
124MP0005381_digestive/alimentary_phenotyp0.38755583
125MP0002970_abnormal_white_adipose0.37547791
126MP0003806_abnormal_nucleotide_metabolis0.37046035
127MP0003959_abnormal_lean_body0.36844493
128MP0003633_abnormal_nervous_system0.36397170
129MP0002822_catalepsy0.35519001
130MP0009643_abnormal_urine_homeostasis0.35352417
131MP0000249_abnormal_blood_vessel0.34150619
132MP0004145_abnormal_muscle_electrophysio0.34000352
133MP0003693_abnormal_embryo_hatching0.33979359
134MP0003567_abnormal_fetal_cardiomyocyte0.32412647
135MP0008873_increased_physiological_sensi0.32267317

Predicted human phenotypes

RankGene SetZ-score
1Severe combined immunodeficiency (HP:0004430)8.36192212
2T lymphocytopenia (HP:0005403)7.26945414
3Combined immunodeficiency (HP:0005387)7.26765573
4Optic neuritis (HP:0100653)7.18775965
5Retrobulbar optic neuritis (HP:0100654)7.18775965
6Stomatitis (HP:0010280)7.07785849
7Abnormality of T cell number (HP:0011839)7.05785476
8Orchitis (HP:0100796)6.63413444
9Myositis (HP:0100614)6.62819291
10Panhypogammaglobulinemia (HP:0003139)6.02228537
11Eczematoid dermatitis (HP:0000976)5.99856682
12Recurrent fungal infections (HP:0002841)5.26549496
13Abnormality of T cells (HP:0002843)5.20691369
14Recurrent bronchitis (HP:0002837)5.13294840
15IgG deficiency (HP:0004315)5.10367033
16Keratoconjunctivitis sicca (HP:0001097)5.00751830
17Keratoconjunctivitis (HP:0001096)4.59151591
18Chronic diarrhea (HP:0002028)4.51443712
19Chronic mucocutaneous candidiasis (HP:0002728)4.39682976
20Recurrent cutaneous fungal infections (HP:0011370)4.39682976
21Abnormality of eosinophils (HP:0001879)4.18454572
22Elevated erythrocyte sedimentation rate (HP:0003565)4.07171428
23Hypoplasia of the thymus (HP:0000778)3.99013142
24Chronic otitis media (HP:0000389)3.95994612
25Autoimmune hemolytic anemia (HP:0001890)3.90488988
26Encephalitis (HP:0002383)3.87916119
27Microvesicular hepatic steatosis (HP:0001414)3.83791310
28IgM deficiency (HP:0002850)3.82605894
29Mitral stenosis (HP:0001718)3.77215038
30Recurrent viral infections (HP:0004429)3.75297648
31Leukocytosis (HP:0001974)3.75195049
32Thyroiditis (HP:0100646)3.69298434
33Nasal polyposis (HP:0100582)3.66009063
34Eosinophilia (HP:0001880)3.64106932
35Increased IgM level (HP:0003496)3.60702564
36Abnormality of T cell physiology (HP:0011840)3.44733853
37Joint swelling (HP:0001386)3.40477112
38Gastrointestinal infarctions (HP:0005244)3.40401250
39Lymphopenia (HP:0001888)3.36629941
40Abnormality of cells of the lymphoid lineage (HP:0012140)3.24578874
41B lymphocytopenia (HP:0010976)3.24005811
42Abnormality of B cell number (HP:0010975)3.24005811
43Gangrene (HP:0100758)3.11441917
44IgA deficiency (HP:0002720)3.09428107
45Pustule (HP:0200039)3.04077000
46Abnormality of the nasal mucosa (HP:0000433)3.04044729
47Type I transferrin isoform profile (HP:0003642)3.02898919
48Granulocytopenia (HP:0001913)2.97793506
493-Methylglutaconic aciduria (HP:0003535)2.91345799
50Anorexia (HP:0002039)2.90772850
51Hypoproteinemia (HP:0003075)2.77422567
52Bronchitis (HP:0012387)2.76710704
53Abnormality of alanine metabolism (HP:0010916)2.74197403
54Hyperalaninemia (HP:0003348)2.74197403
55Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.74197403
56Round ear (HP:0100830)2.74115557
57Arterial thrombosis (HP:0004420)2.71226607
58Mutism (HP:0002300)2.70812552
59Pulmonary embolism (HP:0002204)2.67922234
60Increased IgE level (HP:0003212)2.66724628
61Wrist flexion contracture (HP:0001239)2.64940965
62J-shaped sella turcica (HP:0002680)2.60903796
63Inflammation of the large intestine (HP:0002037)2.60317942
64Abnormal delayed hypersensitivity skin test (HP:0002963)2.56925688
65Thrombocytosis (HP:0001894)2.51879638
66Neuroendocrine neoplasm (HP:0100634)2.49922416
67Slow saccadic eye movements (HP:0000514)2.47665317
68Hypoplastic ischia (HP:0003175)2.47275041
69Respiratory difficulties (HP:0002880)2.47007966
70Hypergammaglobulinemia (HP:0010702)2.45394215
71Abnormality of the endocardium (HP:0004306)2.44811439
72Acne (HP:0001061)2.42028368
73Recurrent sinusitis (HP:0011108)2.41299877
74Gastrointestinal inflammation (HP:0004386)2.40011978
75Progressive inability to walk (HP:0002505)2.39864940
76Menstrual irregularities (HP:0000858)2.38394922
77Supranuclear gaze palsy (HP:0000605)2.36522607
78Keratitis (HP:0000491)2.34930361
79Hepatitis (HP:0012115)2.29884760
80Stomach cancer (HP:0012126)2.25605719
81Frequent falls (HP:0002359)2.25321140
82Sparse scalp hair (HP:0002209)2.24724521
83Inability to walk (HP:0002540)2.23326732
84Mediastinal lymphadenopathy (HP:0100721)2.21642107
85Recurrent skin infections (HP:0001581)2.21106280
86Amyotrophic lateral sclerosis (HP:0007354)2.20832006
87Abnormality of the pleura (HP:0002103)2.18831264
88Abnormality of the labia minora (HP:0012880)2.15647672
89Abnormality of lateral ventricle (HP:0030047)2.13980177
90Vasculitis (HP:0002633)2.13521217
91Cheilitis (HP:0100825)2.13005549
92Villous atrophy (HP:0011473)2.12707005
93Abnormality of small intestinal villus morphology (HP:0011472)2.12707005
94Obstructive lung disease (HP:0006536)2.11878249
95Chronic obstructive pulmonary disease (HP:0006510)2.11878249
96Hypoplasia of the capital femoral epiphysis (HP:0003090)2.07418123
97Reduced antithrombin III activity (HP:0001976)2.06432561
98Polyneuropathy (HP:0001271)2.06158655
99Trigonocephaly (HP:0000243)2.06017830
100Verrucae (HP:0200043)2.05099947
101Papilloma (HP:0012740)2.05099947
102Glomerulopathy (HP:0100820)2.03668178
103Agammaglobulinemia (HP:0004432)2.03129533
104Spontaneous hematomas (HP:0007420)2.02460894
105Lymphoma (HP:0002665)2.00832252
106Chest pain (HP:0100749)2.00562565
107Fatigue (HP:0012378)2.00284752
108Homocystinuria (HP:0002156)1.96365053
109Abnormality of homocysteine metabolism (HP:0010919)1.96365053
110Aplasia/Hypoplasia of the thymus (HP:0010515)1.95919345
111Hemoptysis (HP:0002105)1.95062063
112Abnormality of the ischium (HP:0003174)1.94332873
113Proximal tubulopathy (HP:0000114)1.92030571
114Microcytic anemia (HP:0001935)1.90209718
115Long toe (HP:0010511)1.88708520
116Meningitis (HP:0001287)1.86853603
117Congenital stationary night blindness (HP:0007642)1.85051984
118Hyperlipoproteinemia (HP:0010980)1.84290611
119Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.84147632
120Urinary urgency (HP:0000012)1.83794798
121Beaking of vertebral bodies (HP:0004568)1.82848826
122Recurrent abscess formation (HP:0002722)1.82062870
123Recurrent bacterial skin infections (HP:0005406)1.80682581
124Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.80399897
125Autoimmune thrombocytopenia (HP:0001973)1.79910966
126Large for gestational age (HP:0001520)1.78862130
127Chronic sinusitis (HP:0011109)1.78681261
128Multiple enchondromatosis (HP:0005701)1.78379842
129Abnormal auditory evoked potentials (HP:0006958)1.78373551
130Alveolar cell carcinoma (HP:0006519)1.77879733
131Abnormality of the pericardium (HP:0001697)1.76854476
132Skin rash (HP:0000988)1.75788324
133Pulmonary infiltrates (HP:0002113)1.74871445
134Renal cortical cysts (HP:0000803)1.74804832
135Abnormality of the alveolar ridges (HP:0006477)1.73566579
136Arthrogryposis multiplex congenita (HP:0002804)1.73225363
137Impaired smooth pursuit (HP:0007772)1.71491858
138Gastrointestinal stroma tumor (HP:0100723)1.71213209
139Exertional dyspnea (HP:0002875)1.69492760
140Emphysema (HP:0002097)1.69339136
141Prolonged bleeding time (HP:0003010)1.69033507
142Neonatal hypoglycemia (HP:0001998)1.68760908
143Abnormality of macular pigmentation (HP:0008002)1.68023400
144Type II lissencephaly (HP:0007260)1.67526386
145Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67337877
146Abnormal protein N-linked glycosylation (HP:0012347)1.67337877
147Abnormal protein glycosylation (HP:0012346)1.67337877
148Abnormal glycosylation (HP:0012345)1.67337877
149Epistaxis (HP:0000421)1.66359971
150Global brain atrophy (HP:0002283)1.66149416
151Neoplasm of the tracheobronchial system (HP:0100552)1.65573118
152Severe visual impairment (HP:0001141)1.65365752
153Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.64423517
154Absent epiphyses (HP:0010577)1.64423517
155Upper limb muscle weakness (HP:0003484)1.63814106
156Increased serum lactate (HP:0002151)1.63301331
157Decreased electroretinogram (ERG) amplitude (HP:0000654)1.62438468

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.01694746
2TXK5.00204832
3ZAP704.20266836
4MAP4K14.13456246
5MAP3K103.60759004
6TESK23.55685600
7KDR3.47207481
8VRK23.22609229
9EIF2AK13.15711789
10NEK92.94852303
11IKBKE2.82940547
12JAK32.64121623
13NLK2.54047509
14ITK2.49872153
15VRK12.25736469
16NME22.25012679
17BTK2.18316984
18IRAK42.13533510
19SIK32.02288082
20LCK1.99606100
21TBK11.99326605
22HCK1.98560740
23PDK41.97776220
24PDK31.97776220
25STK101.86967097
26FGFR41.86262972
27TEC1.85623940
28TAOK31.77680887
29MST41.77537986
30GRK61.56993956
31CSK1.55681956
32TYK21.53488244
33TESK11.49222382
34RPS6KA41.46822581
35MAP3K141.38276526
36SMG11.35697734
37MAP3K121.24179201
38LRRK21.23265507
39JAK11.23153710
40ERN11.20593433
41SYK1.17770927
42CAMKK21.17533310
43MAP2K61.14707545
44BCKDK1.09560985
45CDK191.06882981
46MAP3K131.04884787
47LYN1.03611231
48PRKCH1.03070504
49PRKCQ0.99721920
50RIPK40.99593237
51PDK20.96308368
52MAPK110.92420878
53CAMKK10.91273180
54ACVR1B0.91108123
55ADRBK20.89281569
56IRAK30.85903459
57BLK0.78418886
58IRAK10.77360751
59IKBKB0.76769074
60MAP3K30.76649683
61FGFR30.73745176
62TGFBR10.72004649
63NEK10.70339680
64RPS6KB10.70105964
65FYN0.69200165
66MAPKAPK20.69034248
67LIMK10.68115679
68TNK20.67229950
69EEF2K0.66500043
70INSR0.65675405
71IRAK20.64998530
72PIK3CG0.62824053
73TAOK10.58991953
74ZAK0.57451777
75CHUK0.56950142
76DAPK30.55953448
77JAK20.48849692
78IGF1R0.48126454
79PDGFRB0.47691133
80DAPK10.45227281
81PDK10.42661442
82SRC0.41648086
83MARK20.41390404
84MAP2K30.41046984
85PRKACG0.40464540
86TLK10.37557609
87MARK30.37516239
88FGFR10.37158745
89NUAK10.35887429
90FES0.35769577
91HIPK20.35270209
92TYRO30.34885332
93MAP3K70.34204637
94PASK0.33892241
95EIF2AK30.33789082
96STK240.32066290
97MAP3K110.31641948
98ABL10.31130024
99CSF1R0.30664772
100ROCK20.30008809
101PLK30.29247914
102ROCK10.28448749
103YES10.27836733
104TTN0.27221007
105PIM10.26779406
106MAPK90.26527329
107ALK0.26096799
108TGFBR20.25921952
109WNK10.25912489
110RPS6KA50.25328223
111PKN20.23523583
112MAP3K10.23149122
113MAPK40.21829315
114TAF10.21771383
115SIK20.21673210
116CDK120.21474425
117EPHB20.20839044
118KIT0.20424949
119CLK10.20410977
120BMPR1B0.19275689
121TRIM280.18419041
122DMPK0.18201066
123SIK10.18108625
124GRK70.17058237
125MAPK120.16910133
126EPHB10.16621921
127MAPK70.16177516
128FGR0.15992382
129GRK50.15972739
130RPS6KB20.15621443
131STK40.15482469
132NTRK20.15210559
133TRPM70.15189352
134TSSK60.14691661
135EGFR0.13865231
136CSNK2A20.12961641
137EPHA30.12717211
138PRKCD0.12657342
139TRIB30.12382212
140CDK40.11852126
141CAMK10.11606932
142MAPK30.11415736
143SRPK10.10764162
144PRKD20.10628062

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.86321903
2Graft-versus-host disease_Homo sapiens_hsa053324.84249071
3T cell receptor signaling pathway_Homo sapiens_hsa046604.68852542
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.79771456
5Antigen processing and presentation_Homo sapiens_hsa046123.06426395
6Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.84084780
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.76189026
8Measles_Homo sapiens_hsa051622.67780673
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.65512480
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.49702898
11Protein export_Homo sapiens_hsa030602.35234531
12Allograft rejection_Homo sapiens_hsa053302.27358081
13Viral myocarditis_Homo sapiens_hsa054162.26666940
14Caffeine metabolism_Homo sapiens_hsa002322.17505456
15Intestinal immune network for IgA production_Homo sapiens_hsa046721.99767595
16SNARE interactions in vesicular transport_Homo sapiens_hsa041301.94336460
17Hematopoietic cell lineage_Homo sapiens_hsa046401.77341062
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.65718750
19Leishmaniasis_Homo sapiens_hsa051401.64633254
20Autoimmune thyroid disease_Homo sapiens_hsa053201.59836185
21Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.59324509
22Osteoclast differentiation_Homo sapiens_hsa043801.58929349
23Leukocyte transendothelial migration_Homo sapiens_hsa046701.53345869
24B cell receptor signaling pathway_Homo sapiens_hsa046621.51912280
25Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.30977928
26Chemokine signaling pathway_Homo sapiens_hsa040621.28954268
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.28116309
28Jak-STAT signaling pathway_Homo sapiens_hsa046301.24275079
29HTLV-I infection_Homo sapiens_hsa051661.20482550
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.15733378
31Shigellosis_Homo sapiens_hsa051311.15275468
32Type I diabetes mellitus_Homo sapiens_hsa049401.13425212
33Pyrimidine metabolism_Homo sapiens_hsa002401.12981876
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.09313328
35Selenocompound metabolism_Homo sapiens_hsa004501.08289558
36Herpes simplex infection_Homo sapiens_hsa051681.07295706
37Pentose phosphate pathway_Homo sapiens_hsa000301.02069363
38Linoleic acid metabolism_Homo sapiens_hsa005910.92391484
39Colorectal cancer_Homo sapiens_hsa052100.92350588
40VEGF signaling pathway_Homo sapiens_hsa043700.89505791
41Acute myeloid leukemia_Homo sapiens_hsa052210.87283669
42Purine metabolism_Homo sapiens_hsa002300.82068436
43Adherens junction_Homo sapiens_hsa045200.80868482
44Salmonella infection_Homo sapiens_hsa051320.79869034
45Pyruvate metabolism_Homo sapiens_hsa006200.78959046
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.78929177
47Mismatch repair_Homo sapiens_hsa034300.77667964
48Legionellosis_Homo sapiens_hsa051340.75347971
49Pancreatic cancer_Homo sapiens_hsa052120.73526618
50Influenza A_Homo sapiens_hsa051640.72690055
51One carbon pool by folate_Homo sapiens_hsa006700.71803189
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71483421
53Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70380936
54Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68504967
55Ribosome_Homo sapiens_hsa030100.67733349
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67442389
57Toxoplasmosis_Homo sapiens_hsa051450.66828131
58Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66351169
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64423108
60N-Glycan biosynthesis_Homo sapiens_hsa005100.64106328
61Sulfur metabolism_Homo sapiens_hsa009200.63265629
62Platelet activation_Homo sapiens_hsa046110.62763996
63Asthma_Homo sapiens_hsa053100.61841526
64Viral carcinogenesis_Homo sapiens_hsa052030.61577881
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.61320048
66Base excision repair_Homo sapiens_hsa034100.61167201
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.60354930
68Circadian rhythm_Homo sapiens_hsa047100.59657508
69Malaria_Homo sapiens_hsa051440.59591099
70RNA polymerase_Homo sapiens_hsa030200.58654234
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.58614568
72Epstein-Barr virus infection_Homo sapiens_hsa051690.54846432
73AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.53189064
74DNA replication_Homo sapiens_hsa030300.52112935
75Spliceosome_Homo sapiens_hsa030400.52065727
76Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50455747
77Hepatitis B_Homo sapiens_hsa051610.49696967
78Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47752554
79Basal transcription factors_Homo sapiens_hsa030220.47450937
80Ether lipid metabolism_Homo sapiens_hsa005650.47296111
81Endocytosis_Homo sapiens_hsa041440.46866165
82Phototransduction_Homo sapiens_hsa047440.46650582
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46264927
84Apoptosis_Homo sapiens_hsa042100.45345944
85Rheumatoid arthritis_Homo sapiens_hsa053230.44547245
86Type II diabetes mellitus_Homo sapiens_hsa049300.44535718
87Staphylococcus aureus infection_Homo sapiens_hsa051500.43429241
88Carbon metabolism_Homo sapiens_hsa012000.43101694
89TNF signaling pathway_Homo sapiens_hsa046680.43047771
90Nucleotide excision repair_Homo sapiens_hsa034200.42902293
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42763720
92Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41909964
93ABC transporters_Homo sapiens_hsa020100.41857320
94Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.41630355
95Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41291079
96Thyroid cancer_Homo sapiens_hsa052160.40731992
97Vitamin B6 metabolism_Homo sapiens_hsa007500.39538146
98Toll-like receptor signaling pathway_Homo sapiens_hsa046200.37238475
99Hepatitis C_Homo sapiens_hsa051600.36673626
100Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.34601309
101RNA degradation_Homo sapiens_hsa030180.34593863
102Rap1 signaling pathway_Homo sapiens_hsa040150.32520812
103Pertussis_Homo sapiens_hsa051330.31892496
104Homologous recombination_Homo sapiens_hsa034400.31571050
105Tuberculosis_Homo sapiens_hsa051520.28744093
106Chronic myeloid leukemia_Homo sapiens_hsa052200.27697876
107Oxidative phosphorylation_Homo sapiens_hsa001900.27334743
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.27047404
109Glycerophospholipid metabolism_Homo sapiens_hsa005640.26726476
110Cardiac muscle contraction_Homo sapiens_hsa042600.26572158
111mRNA surveillance pathway_Homo sapiens_hsa030150.25917020
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.25108787
113Regulation of autophagy_Homo sapiens_hsa041400.25021726
114Neurotrophin signaling pathway_Homo sapiens_hsa047220.24957454
115Biosynthesis of amino acids_Homo sapiens_hsa012300.24775120
116Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.22750975
117Primary bile acid biosynthesis_Homo sapiens_hsa001200.20761800
118MAPK signaling pathway_Homo sapiens_hsa040100.20368164
119HIF-1 signaling pathway_Homo sapiens_hsa040660.19769682
120Ras signaling pathway_Homo sapiens_hsa040140.19464411
121African trypanosomiasis_Homo sapiens_hsa051430.19063199
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.18695852
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18573090
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.18430876
125Phosphatidylinositol signaling system_Homo sapiens_hsa040700.17578278
126Phagosome_Homo sapiens_hsa041450.16174886
127Lysine degradation_Homo sapiens_hsa003100.15734568
128Prolactin signaling pathway_Homo sapiens_hsa049170.15706861
129RNA transport_Homo sapiens_hsa030130.15529576
130Insulin resistance_Homo sapiens_hsa049310.14836841
131Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.13354577
132Fructose and mannose metabolism_Homo sapiens_hsa000510.13106998
133Choline metabolism in cancer_Homo sapiens_hsa052310.12039880
134Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.11832873
135Notch signaling pathway_Homo sapiens_hsa043300.10711851
136Proteasome_Homo sapiens_hsa030500.10620063
137Glycerolipid metabolism_Homo sapiens_hsa005610.09321656

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