

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sequestering of actin monomers (GO:0042989) | 9.46700975 |
| 2 | positive regulation of lamellipodium assembly (GO:0010592) | 8.07457985 |
| 3 | regulation of isotype switching to IgG isotypes (GO:0048302) | 7.36876638 |
| 4 | regulation of respiratory burst (GO:0060263) | 6.95516123 |
| 5 | positive regulation of lamellipodium organization (GO:1902745) | 6.37332026 |
| 6 | positive regulation of macrophage differentiation (GO:0045651) | 6.26490050 |
| 7 | positive thymic T cell selection (GO:0045059) | 6.18265117 |
| 8 | DNA deamination (GO:0045006) | 6.15044750 |
| 9 | cellular response to interleukin-15 (GO:0071350) | 5.99110790 |
| 10 | lymphocyte costimulation (GO:0031294) | 5.84127066 |
| 11 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 5.81539341 |
| 12 | response to xenobiotic stimulus (GO:0009410) | 5.74901977 |
| 13 | negative thymic T cell selection (GO:0045060) | 5.71930159 |
| 14 | T cell costimulation (GO:0031295) | 5.70825711 |
| 15 | negative regulation of necroptotic process (GO:0060546) | 5.70315825 |
| 16 | T cell migration (GO:0072678) | 5.61563392 |
| 17 | antigen processing and presentation via MHC class Ib (GO:0002475) | 5.40746785 |
| 18 | negative T cell selection (GO:0043383) | 5.38285677 |
| 19 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 5.23087793 |
| 20 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.14830370 |
| 21 | negative regulation of cell killing (GO:0031342) | 5.14830370 |
| 22 | T cell receptor signaling pathway (GO:0050852) | 5.10396209 |
| 23 | negative regulation of B cell mediated immunity (GO:0002713) | 5.06055488 |
| 24 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 5.06055488 |
| 25 | regulation of necroptotic process (GO:0060544) | 5.04257419 |
| 26 | thymic T cell selection (GO:0045061) | 4.95785976 |
| 27 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.82290597 |
| 28 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.82290597 |
| 29 | negative regulation of type 2 immune response (GO:0002829) | 4.70136616 |
| 30 | response to interleukin-15 (GO:0070672) | 4.64969231 |
| 31 | antigen receptor-mediated signaling pathway (GO:0050851) | 4.58518618 |
| 32 | negative regulation of necrotic cell death (GO:0060547) | 4.56313223 |
| 33 | regulation of necrotic cell death (GO:0010939) | 4.56222490 |
| 34 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.50978386 |
| 35 | positive T cell selection (GO:0043368) | 4.50918564 |
| 36 | positive regulation of astrocyte differentiation (GO:0048711) | 4.48147621 |
| 37 | cellular response to zinc ion (GO:0071294) | 4.46653969 |
| 38 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.45034930 |
| 39 | mucosal-associated lymphoid tissue development (GO:0048537) | 4.43541080 |
| 40 | Peyers patch development (GO:0048541) | 4.43541080 |
| 41 | regulation of lamellipodium assembly (GO:0010591) | 4.42369556 |
| 42 | catecholamine transport (GO:0051937) | 4.37650402 |
| 43 | norepinephrine metabolic process (GO:0042415) | 4.37092057 |
| 44 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.21184595 |
| 45 | regulation of isotype switching (GO:0045191) | 4.10745610 |
| 46 | defense response to protozoan (GO:0042832) | 4.10159864 |
| 47 | leukocyte cell-cell adhesion (GO:0007159) | 4.03300394 |
| 48 | regulation of immunoglobulin secretion (GO:0051023) | 3.95431287 |
| 49 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.91811911 |
| 50 | isotype switching (GO:0045190) | 3.90560832 |
| 51 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.90560832 |
| 52 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.90560832 |
| 53 | regulation of immunoglobulin production (GO:0002637) | 3.83313504 |
| 54 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.70583611 |
| 55 | positive regulation of neutrophil chemotaxis (GO:0090023) | 3.69459959 |
| 56 | positive regulation of neutrophil migration (GO:1902624) | 3.69459959 |
| 57 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.67978498 |
| 58 | T cell selection (GO:0045058) | 3.67142228 |
| 59 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.66264630 |
| 60 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.62708581 |
| 61 | negative regulation of phagocytosis (GO:0050765) | 3.59933159 |
| 62 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.56466159 |
| 63 | regulation of macrophage differentiation (GO:0045649) | 3.55306281 |
| 64 | regulation of B cell mediated immunity (GO:0002712) | 3.53924848 |
| 65 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.47805755 |
| 66 | positive regulation of isotype switching (GO:0045830) | 3.47012997 |
| 67 | positive regulation of granulocyte chemotaxis (GO:0071624) | 3.44803940 |
| 68 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.43081336 |
| 69 | response to protozoan (GO:0001562) | 3.42256129 |
| 70 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.38439358 |
| 71 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.35816338 |
| 72 | natural killer cell activation (GO:0030101) | 3.35054023 |
| 73 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.34713186 |
| 74 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 3.33660477 |
| 75 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.32355320 |
| 76 | T-helper cell differentiation (GO:0042093) | 3.32355320 |
| 77 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.31125847 |
| 78 | regulation of lamellipodium organization (GO:1902743) | 3.29325976 |
| 79 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.28064338 |
| 80 | chemokine-mediated signaling pathway (GO:0070098) | 3.27610153 |
| 81 | tolerance induction (GO:0002507) | 3.27267853 |
| 82 | regulation of B cell differentiation (GO:0045577) | 3.26023938 |
| 83 | regulation of response to interferon-gamma (GO:0060330) | 3.22026811 |
| 84 | actin nucleation (GO:0045010) | 3.21866694 |
| 85 | lymphocyte migration (GO:0072676) | 3.18699931 |
| 86 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 3.16683430 |
| 87 | regulation of cell killing (GO:0031341) | 3.15585724 |
| 88 | immune response-activating cell surface receptor signaling pathway (GO:0002429) | 3.15044706 |
| 89 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.13939078 |
| 90 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.09301949 |
| 91 | B cell proliferation (GO:0042100) | 3.08350930 |
| 92 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.02711178 |
| 93 | actin filament depolymerization (GO:0030042) | 3.02695856 |
| 94 | positive regulation of cell killing (GO:0031343) | 3.02133746 |
| 95 | regulation of T cell tolerance induction (GO:0002664) | 3.00423140 |
| 96 | bone resorption (GO:0045453) | 2.99375200 |
| 97 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.98067563 |
| 98 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.98067563 |
| 99 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 11.8394332 |
| 100 | leukocyte aggregation (GO:0070486) | 10.1389978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.32146938 |
| 2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.86679985 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.56865575 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.45035278 |
| 5 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 4.27399007 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.03015069 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.71219717 |
| 8 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.65288828 |
| 9 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.61311127 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.48781617 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.18593107 |
| 12 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.03906960 |
| 13 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.97927473 |
| 14 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.97149250 |
| 15 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.92819179 |
| 16 | MYB_26560356_Chip-Seq_TH2_Human | 2.67267796 |
| 17 | MAF_26560356_Chip-Seq_TH1_Human | 2.66246500 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.59641796 |
| 19 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.50759616 |
| 20 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.49661781 |
| 21 | MYB_26560356_Chip-Seq_TH1_Human | 2.30638649 |
| 22 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.28194422 |
| 23 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.25485732 |
| 24 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.12341874 |
| 25 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.83396108 |
| 26 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.82645516 |
| 27 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.81142414 |
| 28 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.75037324 |
| 29 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71506681 |
| 30 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69044480 |
| 31 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.68229190 |
| 32 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.61118945 |
| 33 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.60431416 |
| 34 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.58972676 |
| 35 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.56055156 |
| 36 | MYC_22102868_ChIP-Seq_BL_Human | 1.47449511 |
| 37 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47241647 |
| 38 | MAF_26560356_Chip-Seq_TH2_Human | 1.41722844 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.41443926 |
| 40 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.38046792 |
| 41 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.37046554 |
| 42 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.36425308 |
| 43 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.36346237 |
| 44 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.35542823 |
| 45 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.34183991 |
| 46 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.33868043 |
| 47 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31289760 |
| 48 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.30998294 |
| 49 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.28847874 |
| 50 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.26127034 |
| 51 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.25931280 |
| 52 | GATA1_22025678_ChIP-Seq_K562_Human | 1.25158298 |
| 53 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.23040599 |
| 54 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.20267967 |
| 55 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.20095157 |
| 56 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.19758688 |
| 57 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19669884 |
| 58 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19306339 |
| 59 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.19044150 |
| 60 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.17548506 |
| 61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.17183399 |
| 62 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.16071426 |
| 63 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.14368881 |
| 64 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.13872587 |
| 65 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.12633826 |
| 66 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.11661806 |
| 67 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.10697921 |
| 68 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.10583574 |
| 69 | SPI1_23127762_ChIP-Seq_K562_Human | 1.08940728 |
| 70 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.08627543 |
| 71 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.08432303 |
| 72 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 1.07892855 |
| 73 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 1.06183394 |
| 74 | GATA3_26560356_Chip-Seq_TH2_Human | 1.03834276 |
| 75 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.02569082 |
| 76 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.01789592 |
| 77 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.01273424 |
| 78 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.00463628 |
| 79 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.98204969 |
| 80 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.97553986 |
| 81 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.97025259 |
| 82 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95570106 |
| 83 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95130210 |
| 84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.94677926 |
| 85 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.93880826 |
| 86 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.92927738 |
| 87 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.92718155 |
| 88 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.92632982 |
| 89 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.92530388 |
| 90 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.91542673 |
| 91 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.91036239 |
| 92 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.90295698 |
| 93 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.89516412 |
| 94 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.89495681 |
| 95 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.88651968 |
| 96 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88083448 |
| 97 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.86526920 |
| 98 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85085139 |
| 99 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.84953334 |
| 100 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.84585115 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.35813052 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.42268486 |
| 3 | MP0000685_abnormal_immune_system | 4.32618785 |
| 4 | MP0003763_abnormal_thymus_physiology | 4.14404129 |
| 5 | MP0009785_altered_susceptibility_to | 4.03573054 |
| 6 | MP0006082_CNS_inflammation | 3.55339260 |
| 7 | MP0003724_increased_susceptibility_to | 3.49377095 |
| 8 | MP0002909_abnormal_adrenal_gland | 3.32761874 |
| 9 | MP0003329_amyloid_beta_deposits | 3.20623651 |
| 10 | MP0005387_immune_system_phenotype | 3.01223640 |
| 11 | MP0001790_abnormal_immune_system | 3.01223640 |
| 12 | MP0002166_altered_tumor_susceptibility | 2.95023510 |
| 13 | MP0005025_abnormal_response_to | 2.74731904 |
| 14 | MP0004510_myositis | 2.67086540 |
| 15 | MP0005000_abnormal_immune_tolerance | 2.59425050 |
| 16 | MP0001853_heart_inflammation | 2.52296247 |
| 17 | MP0003866_abnormal_defecation | 2.49520103 |
| 18 | MP0002420_abnormal_adaptive_immunity | 2.47770376 |
| 19 | MP0001819_abnormal_immune_cell | 2.42785223 |
| 20 | MP0003252_abnormal_bile_duct | 2.38604201 |
| 21 | MP0002723_abnormal_immune_serum | 2.37920425 |
| 22 | MP0002405_respiratory_system_inflammati | 2.37514500 |
| 23 | MP0001800_abnormal_humoral_immune | 2.32650386 |
| 24 | MP0002006_tumorigenesis | 2.30745375 |
| 25 | MP0002933_joint_inflammation | 2.26329752 |
| 26 | MP0002398_abnormal_bone_marrow | 2.25596328 |
| 27 | MP0000604_amyloidosis | 2.16828784 |
| 28 | MP0004947_skin_inflammation | 2.06927181 |
| 29 | MP0010352_gastrointestinal_tract_polyps | 2.05754489 |
| 30 | MP0000716_abnormal_immune_system | 2.03387032 |
| 31 | MP0002452_abnormal_antigen_presenting | 1.99126380 |
| 32 | MP0005310_abnormal_salivary_gland | 1.96406152 |
| 33 | MP0005083_abnormal_biliary_tract | 1.90558175 |
| 34 | MP0002722_abnormal_immune_system | 1.86699382 |
| 35 | MP0000689_abnormal_spleen_morphology | 1.75675950 |
| 36 | MP0009333_abnormal_splenocyte_physiolog | 1.67431636 |
| 37 | MP0002396_abnormal_hematopoietic_system | 1.65084892 |
| 38 | MP0009764_decreased_sensitivity_to | 1.58855465 |
| 39 | MP0002419_abnormal_innate_immunity | 1.57599339 |
| 40 | MP0010155_abnormal_intestine_physiology | 1.56663062 |
| 41 | MP0003436_decreased_susceptibility_to | 1.56497105 |
| 42 | MP0002429_abnormal_blood_cell | 1.55557218 |
| 43 | MP0000703_abnormal_thymus_morphology | 1.53399392 |
| 44 | MP0002132_abnormal_respiratory_system | 1.44813108 |
| 45 | MP0008469_abnormal_protein_level | 1.38811103 |
| 46 | MP0001348_abnormal_lacrimal_gland | 1.38282330 |
| 47 | MP0002148_abnormal_hypersensitivity_rea | 1.35058401 |
| 48 | MP0001845_abnormal_inflammatory_respons | 1.18388374 |
| 49 | MP0009763_increased_sensitivity_to | 1.14859026 |
| 50 | MP0000015_abnormal_ear_pigmentation | 1.13812709 |
| 51 | MP0005464_abnormal_platelet_physiology | 1.12299691 |
| 52 | MP0000639_abnormal_adrenal_gland | 1.10282394 |
| 53 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09683747 |
| 54 | MP0001873_stomach_inflammation | 1.09640515 |
| 55 | MP0000858_altered_metastatic_potential | 1.07681562 |
| 56 | MP0003045_fibrosis | 1.05760664 |
| 57 | MP0004381_abnormal_hair_follicle | 1.04370194 |
| 58 | MP0001851_eye_inflammation | 1.03036707 |
| 59 | MP0005058_abnormal_lysosome_morphology | 1.00231718 |
| 60 | MP0005330_cardiomyopathy | 0.99504184 |
| 61 | MP0009840_abnormal_foam_cell | 0.94626402 |
| 62 | MP0001533_abnormal_skeleton_physiology | 0.94085157 |
| 63 | MP0009765_abnormal_xenobiotic_induced | 0.90642565 |
| 64 | MP0003828_pulmonary_edema | 0.90302091 |
| 65 | MP0010386_abnormal_urinary_bladder | 0.89600990 |
| 66 | MP0005166_decreased_susceptibility_to | 0.89267644 |
| 67 | MP0005023_abnormal_wound_healing | 0.87577942 |
| 68 | MP0009379_abnormal_foot_pigmentation | 0.82722122 |
| 69 | MP0004145_abnormal_muscle_electrophysio | 0.82069486 |
| 70 | MP0002019_abnormal_tumor_incidence | 0.80818261 |
| 71 | MP0005165_increased_susceptibility_to | 0.80658996 |
| 72 | MP0000343_altered_response_to | 0.79671178 |
| 73 | MP0000920_abnormal_myelination | 0.77419960 |
| 74 | MP0003633_abnormal_nervous_system | 0.76658737 |
| 75 | MP0001984_abnormal_olfaction | 0.76289836 |
| 76 | MP0002095_abnormal_skin_pigmentation | 0.75960474 |
| 77 | MP0002822_catalepsy | 0.73065590 |
| 78 | MP0003453_abnormal_keratinocyte_physiol | 0.66872997 |
| 79 | MP0001243_abnormal_dermal_layer | 0.66151956 |
| 80 | MP0003448_altered_tumor_morphology | 0.65906873 |
| 81 | MP0002928_abnormal_bile_duct | 0.63981655 |
| 82 | MP0005451_abnormal_body_composition | 0.62249959 |
| 83 | MP0000477_abnormal_intestine_morphology | 0.61385183 |
| 84 | MP0002693_abnormal_pancreas_physiology | 0.55232987 |
| 85 | MP0008007_abnormal_cellular_replicative | 0.54156535 |
| 86 | MP0005647_abnormal_sex_gland | 0.51856275 |
| 87 | MP0010234_abnormal_vibrissa_follicle | 0.47318018 |
| 88 | MP0003221_abnormal_cardiomyocyte_apopto | 0.46207142 |
| 89 | MP0005085_abnormal_gallbladder_physiolo | 0.45538475 |
| 90 | MP0001881_abnormal_mammary_gland | 0.45505266 |
| 91 | MP0000609_abnormal_liver_physiology | 0.45158283 |
| 92 | MP0002168_other_aberrant_phenotype | 0.44790225 |
| 93 | MP0009642_abnormal_blood_homeostasis | 0.44446954 |
| 94 | MP0008873_increased_physiological_sensi | 0.43202359 |
| 95 | MP0000627_abnormal_mammary_gland | 0.42679603 |
| 96 | MP0000249_abnormal_blood_vessel | 0.40855993 |
| 97 | MP0004147_increased_porphyrin_level | 0.39719347 |
| 98 | MP0008569_lethality_at_weaning | 0.38814826 |
| 99 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.38173174 |
| 100 | MP0003303_peritoneal_inflammation | 0.36278879 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased IgM level (HP:0003496) | 9.92503402 |
| 2 | Stomatitis (HP:0010280) | 8.70909046 |
| 3 | Severe combined immunodeficiency (HP:0004430) | 8.18062777 |
| 4 | IgG deficiency (HP:0004315) | 7.17731904 |
| 5 | Combined immunodeficiency (HP:0005387) | 6.91348896 |
| 6 | Abnormality of T cell physiology (HP:0011840) | 5.38225790 |
| 7 | Eczematoid dermatitis (HP:0000976) | 5.27822744 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.27403544 |
| 9 | Recurrent bronchitis (HP:0002837) | 5.22358569 |
| 10 | Abnormality of T cells (HP:0002843) | 5.19028039 |
| 11 | IgM deficiency (HP:0002850) | 4.97717949 |
| 12 | IgA deficiency (HP:0002720) | 4.84621266 |
| 13 | Autoimmune hemolytic anemia (HP:0001890) | 4.71161555 |
| 14 | Thyroiditis (HP:0100646) | 4.64402545 |
| 15 | T lymphocytopenia (HP:0005403) | 4.61036650 |
| 16 | Abnormality of T cell number (HP:0011839) | 4.48286219 |
| 17 | Chronic diarrhea (HP:0002028) | 4.28003739 |
| 18 | Gingivitis (HP:0000230) | 4.26112668 |
| 19 | Hypoplasia of the thymus (HP:0000778) | 4.18178703 |
| 20 | Hypergammaglobulinemia (HP:0010702) | 4.10484010 |
| 21 | Amyotrophic lateral sclerosis (HP:0007354) | 3.78003688 |
| 22 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.29455516 |
| 23 | Recurrent cutaneous fungal infections (HP:0011370) | 3.29455516 |
| 24 | Gastrointestinal infarctions (HP:0005244) | 3.23390407 |
| 25 | Abnormality of eosinophils (HP:0001879) | 3.22664429 |
| 26 | Aplastic anemia (HP:0001915) | 3.19917152 |
| 27 | 3-Methylglutaconic aciduria (HP:0003535) | 3.14314303 |
| 28 | Oral leukoplakia (HP:0002745) | 3.13123860 |
| 29 | Nasal polyposis (HP:0100582) | 3.08575297 |
| 30 | Recurrent fungal infections (HP:0002841) | 3.03698627 |
| 31 | Chronic otitis media (HP:0000389) | 3.02538676 |
| 32 | Increased intramyocellular lipid droplets (HP:0012240) | 3.02291764 |
| 33 | Lymphopenia (HP:0001888) | 2.99664877 |
| 34 | Bronchitis (HP:0012387) | 2.94073580 |
| 35 | Hypoproteinemia (HP:0003075) | 2.91826144 |
| 36 | B lymphocytopenia (HP:0010976) | 2.91506881 |
| 37 | Abnormality of B cell number (HP:0010975) | 2.91506881 |
| 38 | Hepatitis (HP:0012115) | 2.84538470 |
| 39 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.83589293 |
| 40 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.82986024 |
| 41 | Radial bowing (HP:0002986) | 2.77139503 |
| 42 | Type 2 muscle fiber atrophy (HP:0003554) | 2.75615251 |
| 43 | Panhypogammaglobulinemia (HP:0003139) | 2.74424430 |
| 44 | Increased muscle lipid content (HP:0009058) | 2.70686657 |
| 45 | Leukocytosis (HP:0001974) | 2.69538272 |
| 46 | Abnormality of the nasal mucosa (HP:0000433) | 2.61848517 |
| 47 | Frequent falls (HP:0002359) | 2.61203063 |
| 48 | Recurrent sinusitis (HP:0011108) | 2.60502526 |
| 49 | Muscle fiber atrophy (HP:0100295) | 2.52148517 |
| 50 | Urinary urgency (HP:0000012) | 2.52083625 |
| 51 | Neuroendocrine neoplasm (HP:0100634) | 2.47585381 |
| 52 | Albinism (HP:0001022) | 2.46589117 |
| 53 | Pulmonary fibrosis (HP:0002206) | 2.37011722 |
| 54 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.34227228 |
| 55 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.34227228 |
| 56 | Vacuolated lymphocytes (HP:0001922) | 2.31143600 |
| 57 | Subacute progressive viral hepatitis (HP:0006572) | 2.27992719 |
| 58 | Recurrent otitis media (HP:0000403) | 2.27924719 |
| 59 | Recurrent abscess formation (HP:0002722) | 2.21978749 |
| 60 | Large eyes (HP:0001090) | 2.12415848 |
| 61 | Vasculitis (HP:0002633) | 2.12088403 |
| 62 | Lymphoma (HP:0002665) | 2.10732608 |
| 63 | Myositis (HP:0100614) | 2.09949685 |
| 64 | Gastrointestinal stroma tumor (HP:0100723) | 2.09129833 |
| 65 | Recurrent skin infections (HP:0001581) | 2.07350947 |
| 66 | Micronodular cirrhosis (HP:0001413) | 2.02589459 |
| 67 | Hepatocellular necrosis (HP:0001404) | 1.99970353 |
| 68 | Joint swelling (HP:0001386) | 1.96900267 |
| 69 | Neutropenia (HP:0001875) | 1.96423126 |
| 70 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.94846293 |
| 71 | Hemoptysis (HP:0002105) | 1.93180498 |
| 72 | Microcytic anemia (HP:0001935) | 1.88364912 |
| 73 | Increased hepatocellular lipid droplets (HP:0006565) | 1.85811722 |
| 74 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.85202520 |
| 75 | Agammaglobulinemia (HP:0004432) | 1.84776720 |
| 76 | Hypoplasia of the ulna (HP:0003022) | 1.83024370 |
| 77 | Premature graying of hair (HP:0002216) | 1.81031445 |
| 78 | Diplopia (HP:0000651) | 1.80495301 |
| 79 | Abnormality of binocular vision (HP:0011514) | 1.80495301 |
| 80 | Chronic obstructive pulmonary disease (HP:0006510) | 1.80204021 |
| 81 | Obstructive lung disease (HP:0006536) | 1.80204021 |
| 82 | Renal cortical cysts (HP:0000803) | 1.79968594 |
| 83 | Anorexia (HP:0002039) | 1.77090569 |
| 84 | Hepatic necrosis (HP:0002605) | 1.76057847 |
| 85 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.75372946 |
| 86 | Bowing of the arm (HP:0006488) | 1.74759743 |
| 87 | Bowed forearm bones (HP:0003956) | 1.74759743 |
| 88 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.73556302 |
| 89 | Abnormal platelet function (HP:0011869) | 1.71061760 |
| 90 | Impaired platelet aggregation (HP:0003540) | 1.71061760 |
| 91 | Gangrene (HP:0100758) | 1.70836359 |
| 92 | Hypoalbuminemia (HP:0003073) | 1.67708049 |
| 93 | Abnormal albumin level (HP:0012116) | 1.67708049 |
| 94 | Renal Fanconi syndrome (HP:0001994) | 1.66308231 |
| 95 | Pulmonary infiltrates (HP:0002113) | 1.65928912 |
| 96 | Lipid accumulation in hepatocytes (HP:0006561) | 1.63899665 |
| 97 | Progressive microcephaly (HP:0000253) | 1.62491291 |
| 98 | Emphysema (HP:0002097) | 1.62447108 |
| 99 | Mediastinal lymphadenopathy (HP:0100721) | 1.58905040 |
| 100 | Easy fatigability (HP:0003388) | 1.58769017 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 8.00052982 |
| 2 | MAP3K12 | 5.37358043 |
| 3 | KDR | 5.30742620 |
| 4 | TESK1 | 4.79531471 |
| 5 | TXK | 3.81805383 |
| 6 | LIMK1 | 3.42279801 |
| 7 | ZAP70 | 3.41748603 |
| 8 | MAP4K1 | 3.26829264 |
| 9 | BUB1 | 3.18693447 |
| 10 | EIF2AK1 | 2.61122167 |
| 11 | BLK | 2.35705090 |
| 12 | PIM2 | 1.73531962 |
| 13 | IKBKE | 1.73412501 |
| 14 | MYLK | 1.52335930 |
| 15 | JAK1 | 1.39586046 |
| 16 | TBK1 | 1.38356239 |
| 17 | EIF2AK3 | 1.33784826 |
| 18 | ITK | 1.27902769 |
| 19 | LCK | 1.25614065 |
| 20 | IRAK4 | 1.20304861 |
| 21 | DAPK3 | 1.12027728 |
| 22 | TLK1 | 1.05025855 |
| 23 | ERN1 | 1.03142938 |
| 24 | ARAF | 1.02147234 |
| 25 | SIK1 | 0.98483882 |
| 26 | MAP3K11 | 0.97586553 |
| 27 | LYN | 0.96042019 |
| 28 | RAF1 | 0.95930845 |
| 29 | FGFR1 | 0.92855440 |
| 30 | PRKCQ | 0.92637552 |
| 31 | FGFR4 | 0.92477600 |
| 32 | SYK | 0.92345991 |
| 33 | TEC | 0.91252045 |
| 34 | SIK3 | 0.89615126 |
| 35 | BTK | 0.82734565 |
| 36 | DAPK1 | 0.82122877 |
| 37 | JAK3 | 0.81313118 |
| 38 | IRAK2 | 0.74934585 |
| 39 | TNK2 | 0.70321490 |
| 40 | CLK1 | 0.68923681 |
| 41 | MUSK | 0.67088062 |
| 42 | HCK | 0.66671002 |
| 43 | STK16 | 0.65874247 |
| 44 | ROCK1 | 0.64693287 |
| 45 | NTRK3 | 0.64501211 |
| 46 | GRK6 | 0.59325435 |
| 47 | FYN | 0.58987136 |
| 48 | CDK3 | 0.58138628 |
| 49 | CDK19 | 0.56371777 |
| 50 | SIK2 | 0.52523762 |
| 51 | EIF2AK2 | 0.52498222 |
| 52 | MAP2K7 | 0.47875500 |
| 53 | INSR | 0.45651161 |
| 54 | TYK2 | 0.44555834 |
| 55 | NLK | 0.42954871 |
| 56 | SRC | 0.36194227 |
| 57 | CSK | 0.35996416 |
| 58 | MAP2K6 | 0.34479525 |
| 59 | ABL1 | 0.34146508 |
| 60 | NME1 | 0.33712679 |
| 61 | PRKCD | 0.30469633 |
| 62 | LRRK2 | 0.29583154 |
| 63 | ILK | 0.29488246 |
| 64 | PRKG2 | 0.28472930 |
| 65 | SCYL2 | 0.27342893 |
| 66 | CSNK1G3 | 0.26140092 |
| 67 | PAK4 | 0.24340104 |
| 68 | IGF1R | 0.24282613 |
| 69 | CSNK1A1L | 0.21108064 |
| 70 | JAK2 | 0.20731411 |
| 71 | ERBB4 | 0.20650633 |
| 72 | STK10 | 0.20359224 |
| 73 | KIT | 0.19752028 |
| 74 | PDK3 | 0.18005474 |
| 75 | PDK4 | 0.18005474 |
| 76 | TAOK2 | 0.17702548 |
| 77 | IRAK1 | 0.17412255 |
| 78 | BCKDK | 0.17237903 |
| 79 | CSNK1G2 | 0.17167789 |
| 80 | NME2 | 0.17022517 |
| 81 | PRKCA | 0.15362945 |
| 82 | CSF1R | 0.14702629 |
| 83 | MAP3K1 | 0.14681179 |
| 84 | AURKB | 0.13492302 |
| 85 | TNIK | 0.12840857 |
| 86 | CSNK1A1 | 0.12816571 |
| 87 | MAP3K5 | 0.11823227 |
| 88 | PRKCH | 0.11168883 |
| 89 | IKBKB | 0.09878682 |
| 90 | CDK11A | 0.09219499 |
| 91 | MAP2K4 | 0.09051819 |
| 92 | PRKCI | 0.08694615 |
| 93 | RPS6KA4 | 0.06412370 |
| 94 | CAMK1 | 0.05118621 |
| 95 | VRK1 | 0.04651984 |
| 96 | AURKA | 0.04639678 |
| 97 | ROCK2 | 0.04603773 |
| 98 | CDK15 | 0.04418787 |
| 99 | PRKD1 | 0.04197244 |
| 100 | CDK14 | 0.04002134 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 7.31226783 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 4.85039075 |
| 3 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 4.32110235 |
| 4 | Asthma_Homo sapiens_hsa05310 | 4.16869143 |
| 5 | Viral myocarditis_Homo sapiens_hsa05416 | 3.69683961 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.60414105 |
| 7 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.45598551 |
| 8 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 3.11490288 |
| 9 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.01652808 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.46729986 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.30493817 |
| 12 | Proteasome_Homo sapiens_hsa03050 | 2.25784817 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.02237133 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.99797753 |
| 15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.74436919 |
| 16 | Measles_Homo sapiens_hsa05162 | 1.71991714 |
| 17 | Malaria_Homo sapiens_hsa05144 | 1.71176068 |
| 18 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.36435555 |
| 19 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.25449863 |
| 20 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.22012069 |
| 21 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.10276194 |
| 22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.04195160 |
| 23 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.04181753 |
| 24 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.03634100 |
| 25 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.02985630 |
| 26 | Spliceosome_Homo sapiens_hsa03040 | 0.92354971 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.89167592 |
| 28 | Ribosome_Homo sapiens_hsa03010 | 0.88218647 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.88172759 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.80393121 |
| 31 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.79063104 |
| 32 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.75684064 |
| 33 | Protein export_Homo sapiens_hsa03060 | 0.73159987 |
| 34 | DNA replication_Homo sapiens_hsa03030 | 0.72181486 |
| 35 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.71684794 |
| 36 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.71647503 |
| 37 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.69180076 |
| 38 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.68537091 |
| 39 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.63602368 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.59720859 |
| 41 | Other glycan degradation_Homo sapiens_hsa00511 | 0.57907508 |
| 42 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.55532427 |
| 43 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55313821 |
| 44 | Apoptosis_Homo sapiens_hsa04210 | 0.55242437 |
| 45 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.53761017 |
| 46 | Shigellosis_Homo sapiens_hsa05131 | 0.52743523 |
| 47 | Mismatch repair_Homo sapiens_hsa03430 | 0.52577467 |
| 48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.52531191 |
| 49 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.51341726 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50689886 |
| 51 | Salmonella infection_Homo sapiens_hsa05132 | 0.50594348 |
| 52 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.49793622 |
| 53 | Colorectal cancer_Homo sapiens_hsa05210 | 0.49243427 |
| 54 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49183000 |
| 55 | Homologous recombination_Homo sapiens_hsa03440 | 0.48879881 |
| 56 | Legionellosis_Homo sapiens_hsa05134 | 0.47276776 |
| 57 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46498255 |
| 58 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45671105 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45128520 |
| 60 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.43886713 |
| 61 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.43864069 |
| 62 | Base excision repair_Homo sapiens_hsa03410 | 0.43012998 |
| 63 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41177496 |
| 64 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.40614481 |
| 65 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.39334945 |
| 66 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.38164819 |
| 67 | Carbon metabolism_Homo sapiens_hsa01200 | 0.36685904 |
| 68 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.36370728 |
| 69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.35468894 |
| 70 | Parkinsons disease_Homo sapiens_hsa05012 | 0.30554176 |
| 71 | Alzheimers disease_Homo sapiens_hsa05010 | 0.30233059 |
| 72 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.28042642 |
| 73 | RNA degradation_Homo sapiens_hsa03018 | 0.26684105 |
| 74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26308448 |
| 75 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.26303168 |
| 76 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.23179946 |
| 77 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.23020415 |
| 78 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.22254921 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.20065885 |
| 80 | Lysosome_Homo sapiens_hsa04142 | 0.19217421 |
| 81 | RNA polymerase_Homo sapiens_hsa03020 | 0.18314088 |
| 82 | Hepatitis B_Homo sapiens_hsa05161 | 0.17164850 |
| 83 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.15607544 |
| 84 | Adherens junction_Homo sapiens_hsa04520 | 0.14628972 |
| 85 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.14430649 |
| 86 | Tuberculosis_Homo sapiens_hsa05152 | 0.14287833 |
| 87 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.14268274 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.14240590 |
| 89 | Endocytosis_Homo sapiens_hsa04144 | 0.14026814 |
| 90 | Pertussis_Homo sapiens_hsa05133 | 0.12924156 |
| 91 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.12307689 |
| 92 | ABC transporters_Homo sapiens_hsa02010 | 0.11539603 |
| 93 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.11394690 |
| 94 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.11069871 |
| 95 | Purine metabolism_Homo sapiens_hsa00230 | 0.10732099 |
| 96 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.10004456 |
| 97 | Basal transcription factors_Homo sapiens_hsa03022 | 0.08584644 |
| 98 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.07921039 |
| 99 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.07542291 |
| 100 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.07290802 |

