TRAV12-2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine ribonucleoside catabolic process (GO:0046133)9.91199137
2DNA deamination (GO:0045006)9.44516284
3negative T cell selection (GO:0043383)8.78104675
4negative thymic T cell selection (GO:0045060)8.70307019
5positive regulation of gamma-delta T cell activation (GO:0046645)7.65175171
6regulation of gamma-delta T cell differentiation (GO:0045586)7.52028979
7regulation of isotype switching to IgG isotypes (GO:0048302)7.46285885
8positive thymic T cell selection (GO:0045059)7.39672142
9thymic T cell selection (GO:0045061)7.12942864
10Arp2/3 complex-mediated actin nucleation (GO:0034314)7.01405345
11positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.87162750
12positive T cell selection (GO:0043368)6.80040478
13regulation of gamma-delta T cell activation (GO:0046643)6.76632332
14positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.75015004
15T cell migration (GO:0072678)6.70248600
16interferon-gamma production (GO:0032609)6.62470350
17leukocyte aggregation (GO:0070486)6.52600065
18T cell selection (GO:0045058)6.49073209
19sequestering of actin monomers (GO:0042989)6.30048404
20T cell receptor signaling pathway (GO:0050852)6.21000700
21actin nucleation (GO:0045010)6.18498254
22negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.83152181
23negative regulation of cell killing (GO:0031342)5.83152181
24regulation of T cell tolerance induction (GO:0002664)5.69264732
25response to interleukin-15 (GO:0070672)5.50672363
26cellular response to interleukin-15 (GO:0071350)5.45874512
27T cell costimulation (GO:0031295)5.45076428
28lymphocyte costimulation (GO:0031294)5.37418528
29antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.23780937
30regulation of alpha-beta T cell proliferation (GO:0046640)5.20563217
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.12454861
32antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.12454861
33positive regulation of alpha-beta T cell proliferation (GO:0046641)5.09234429
34regulation of interleukin-2 biosynthetic process (GO:0045076)5.07589715
35regulation of T cell receptor signaling pathway (GO:0050856)5.00986350
36antigen receptor-mediated signaling pathway (GO:0050851)5.00606104
37negative regulation by host of viral transcription (GO:0043922)5.00090269
38cytolysis (GO:0019835)4.98612879
39negative regulation of viral genome replication (GO:0045071)4.87243878
40positive regulation of monocyte chemotaxis (GO:0090026)4.84736560
41regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.73668651
42pyrimidine nucleoside catabolic process (GO:0046135)4.73328185
43positive regulation of interleukin-8 secretion (GO:2000484)4.73215792
44negative regulation of T cell apoptotic process (GO:0070233)4.70089675
45positive regulation of tolerance induction (GO:0002645)4.67949596
46lymphocyte chemotaxis (GO:0048247)4.61013790
47mast cell activation (GO:0045576)4.57280142
48regulation of isotype switching (GO:0045191)4.56801048
49regulation of T cell chemotaxis (GO:0010819)4.51878275
50positive regulation of T cell chemotaxis (GO:0010820)4.51878275
51positive regulation of interleukin-2 production (GO:0032743)4.50532379
52regulation of B cell differentiation (GO:0045577)4.48139118
53regulation of B cell receptor signaling pathway (GO:0050855)4.45769359
54positive regulation of isotype switching (GO:0045830)4.45340875
55regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.37783124
56activated T cell proliferation (GO:0050798)4.34968805
57negative regulation of type 2 immune response (GO:0002829)4.28614456
58positive regulation of B cell differentiation (GO:0045579)4.21319672
59homeostasis of number of cells within a tissue (GO:0048873)4.20585386
60regulation of lymphocyte chemotaxis (GO:1901623)4.20195310
61antigen processing and presentation of endogenous antigen (GO:0019883)4.18782072
62regulation of immunoglobulin production (GO:0002637)4.11794861
63tolerance induction (GO:0002507)4.07160648
64regulation of tolerance induction (GO:0002643)4.04869372
65regulation of immunoglobulin mediated immune response (GO:0002889)4.04420941
66negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)4.02371537
67mast cell activation involved in immune response (GO:0002279)4.01495532
68mast cell degranulation (GO:0043303)4.01495532
69regulation of regulatory T cell differentiation (GO:0045589)4.00256593
70positive regulation of calcium-mediated signaling (GO:0050850)3.99559151
71positive regulation of B cell mediated immunity (GO:0002714)3.96439018
72positive regulation of immunoglobulin mediated immune response (GO:0002891)3.96439018
73barbed-end actin filament capping (GO:0051016)3.95142479
74gap junction assembly (GO:0016264)3.94011977
75negative regulation of stress fiber assembly (GO:0051497)3.93652655
76macrophage chemotaxis (GO:0048246)3.92000738
77positive regulation of natural killer cell mediated immunity (GO:0002717)3.90729512
78positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.90729512
79regulation of defense response to virus by virus (GO:0050690)3.89848564
80regulation of B cell mediated immunity (GO:0002712)3.89297323
81leukocyte cell-cell adhesion (GO:0007159)3.88443317
82regulation of interleukin-12 biosynthetic process (GO:0045075)3.87764376
83regulation of natural killer cell mediated immunity (GO:0002715)3.82513097
84regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.82513097
85alpha-beta T cell differentiation (GO:0046632)3.78193631
86positive regulation of lymphocyte migration (GO:2000403)3.77792088
87regulation of response to interferon-gamma (GO:0060330)3.77079684
88positive regulation of humoral immune response (GO:0002922)3.76746696
89eosinophil chemotaxis (GO:0048245)3.76346505
90lymphocyte migration (GO:0072676)3.76132500
91antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.75303605
92positive regulation of DNA recombination (GO:0045911)3.73685810
93regulation of activation of Janus kinase activity (GO:0010533)3.72025775
94negative regulation of T cell receptor signaling pathway (GO:0050860)3.70777508
95regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.70457740
96T cell differentiation (GO:0030217)3.67427628
97positive regulation of T cell mediated cytotoxicity (GO:0001916)3.65342246
98alpha-beta T cell activation (GO:0046631)3.65213464
99T cell activation (GO:0042110)3.64436108
100regulation of interleukin-8 secretion (GO:2000482)3.56378419
101antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.56267336
102positive regulation of immunoglobulin production (GO:0002639)3.55254377
103positive regulation of cell killing (GO:0031343)3.55141171
104cellular defense response (GO:0006968)3.48349984
105regulation of immunoglobulin secretion (GO:0051023)3.42872476
106CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.42781838
107T-helper cell differentiation (GO:0042093)3.42781838
108positive regulation of T cell migration (GO:2000406)3.41458087
109eosinophil migration (GO:0072677)3.41320415
110positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.40695550
111immune response-activating cell surface receptor signaling pathway (GO:0002429)3.40180202
112positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.40047525
113chemokine-mediated signaling pathway (GO:0070098)3.38083080
114regulation of type I interferon-mediated signaling pathway (GO:0060338)3.37536216
115negative regulation of execution phase of apoptosis (GO:1900118)3.37195112
116positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.35664295
117regulation of viral genome replication (GO:0045069)3.35130917
118regulation of interleukin-2 production (GO:0032663)3.34273995
119regulation of cellular amino acid metabolic process (GO:0006521)3.33984012
120NIK/NF-kappaB signaling (GO:0038061)3.29375183
121negative regulation of lymphocyte apoptotic process (GO:0070229)3.28944902
122regulation of leukocyte mediated cytotoxicity (GO:0001910)3.28002500
123DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.27551102
124Peyers patch development (GO:0048541)3.24391161
125mucosal-associated lymphoid tissue development (GO:0048537)3.24391161
126CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.23823975
127dendritic cell chemotaxis (GO:0002407)3.23549650
128positive regulation of T cell activation (GO:0050870)3.22103582
129negative regulation of T cell mediated immunity (GO:0002710)3.20802254
130ribosomal small subunit assembly (GO:0000028)3.19861155
131positive regulation of interleukin-4 production (GO:0032753)3.19019856
132positive regulation of uterine smooth muscle contraction (GO:0070474)3.18628738
133intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.18079213
134signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.18079213
135respiratory burst (GO:0045730)3.16330593
136regulation of interleukin-4 production (GO:0032673)3.16130367
137regulation of cell killing (GO:0031341)3.15273789
138regulation of monocyte chemotaxis (GO:0090025)3.14212163
139regulation of T cell mediated cytotoxicity (GO:0001914)3.12955400
140negative regulation of phagocytosis (GO:0050765)3.12452113
141positive regulation of T cell differentiation (GO:0045582)3.11953933
142negative regulation of B cell proliferation (GO:0030889)3.11032175
143heterotypic cell-cell adhesion (GO:0034113)3.10643697
144signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.10538909
145signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.10538909
146signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.10538909
147negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.09280227
148maturation of SSU-rRNA (GO:0030490)3.08943166
149positive regulation of T-helper 1 type immune response (GO:0002827)3.08608205
150response to interferon-beta (GO:0035456)3.07735888
151T cell differentiation involved in immune response (GO:0002292)3.07554628
152alpha-beta T cell activation involved in immune response (GO:0002287)3.07554628
153positive regulation of lamellipodium assembly (GO:0010592)3.06779448
154negative regulation of viral process (GO:0048525)3.03886023
155positive regulation of defense response to virus by host (GO:0002230)3.03015858
156negative regulation of actin filament bundle assembly (GO:0032232)3.00404350
157regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:004509111.2374595
158cytidine deamination (GO:0009972)11.0909692
159cytidine metabolic process (GO:0046087)11.0909692
160cytidine catabolic process (GO:0006216)11.0909692

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.30714466
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.16838136
3STAT6_21828071_ChIP-Seq_BEAS2B_Human5.24088651
4RUNX_20019798_ChIP-Seq_JUKART_Human3.97704395
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.82173672
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.76835026
7STAT4_19710469_ChIP-ChIP_TH1__Mouse3.76389817
8MYC_22102868_ChIP-Seq_BL_Human3.71687029
9STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.61348946
10IRF8_22096565_ChIP-ChIP_GC-B_Human3.55383578
11FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.49555572
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.47711164
13MYB_26560356_Chip-Seq_TH2_Human3.10959278
14MAF_26560356_Chip-Seq_TH1_Human3.04533741
15UTX_26944678_Chip-Seq_JUKART_Human2.86750658
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.82844263
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.75513444
18NOTCH1_21737748_ChIP-Seq_TLL_Human2.68808369
19MYB_26560356_Chip-Seq_TH1_Human2.66967288
20RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.52293188
21MAF_26560356_Chip-Seq_TH2_Human2.28405948
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.24004780
23BP1_19119308_ChIP-ChIP_Hs578T_Human2.13115468
24KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.08941221
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.08671863
26GATA3_27048872_Chip-Seq_THYMUS_Human2.06484565
27IRF8_21731497_ChIP-ChIP_J774_Mouse2.05531969
28NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.04571496
29RUNX1_22412390_ChIP-Seq_EML_Mouse1.99696470
30VDR_21846776_ChIP-Seq_THP-1_Human1.99673928
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.97144836
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.94142157
33FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.91374066
34E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.89978372
35SRY_22984422_ChIP-ChIP_TESTIS_Rat1.79250416
36SPI1_23547873_ChIP-Seq_NB4_Human1.78831433
37VDR_24763502_ChIP-Seq_THP-1_Human1.76876133
38KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.71989832
39TCF7_22412390_ChIP-Seq_EML_Mouse1.71916270
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.67824683
41KDM2B_26808549_Chip-Seq_DND41_Human1.65046667
42HTT_18923047_ChIP-ChIP_STHdh_Human1.64481504
43SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.62508969
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62358145
45HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.58162869
46MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.57435823
47NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56885927
48VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.56214731
49MYB_21317192_ChIP-Seq_ERMYB_Mouse1.49580680
50SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.44598658
51E2F7_22180533_ChIP-Seq_HELA_Human1.41192177
52RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.38951706
53SCL_19346495_ChIP-Seq_HPC-7_Human1.38647839
54EGR1_19374776_ChIP-ChIP_THP-1_Human1.36288552
55NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.34687708
56IRF8_27001747_Chip-Seq_BMDM_Mouse1.34182161
57RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.33607363
58KDM2B_26808549_Chip-Seq_SUP-B15_Human1.33226525
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.29289230
60SPI1_23127762_ChIP-Seq_K562_Human1.28277977
61RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.27859864
62CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27652812
63VDR_23849224_ChIP-Seq_CD4+_Human1.25783412
64BCL6_27268052_Chip-Seq_Bcells_Human1.24632164
65CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22236630
66VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.22006347
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.20465093
68THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.20186441
69PU.1_20513432_ChIP-Seq_Bcells_Mouse1.18987935
70PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.15949039
71GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.15524879
72CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15172738
73GABP_17652178_ChIP-ChIP_JURKAT_Human1.14909791
74ZNF263_19887448_ChIP-Seq_K562_Human1.14816604
75ELK3_25401928_ChIP-Seq_HUVEC_Human1.13652289
76FOXP3_21729870_ChIP-Seq_TREG_Human1.12779383
77GATA2_22383799_ChIP-Seq_G1ME_Mouse1.12225047
78BRD4_27068464_Chip-Seq_AML-cells_Mouse1.11435475
79BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.09871807
80CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.09779438
81KDM2B_26808549_Chip-Seq_JURKAT_Human1.09224804
82LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08782836
83TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.07999536
84ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07757065
85PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07326425
86TAF2_19829295_ChIP-Seq_ESCs_Human1.07314625
87GATA3_26560356_Chip-Seq_TH2_Human1.05630123
88EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.04674774
89TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.98772892
90SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98118727
91FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98010412
92EST1_17652178_ChIP-ChIP_JURKAT_Human0.97774794
93PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97247811
94XRN2_22483619_ChIP-Seq_HELA_Human0.97051212
95RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97014889
96SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.96529151
97CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95024384
98PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94929219
99SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.94681278
100NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94444927
101LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.94408092
102HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.93351736
103MYC_18555785_ChIP-Seq_MESCs_Mouse0.92415408
104LXR_22292898_ChIP-Seq_THP-1_Human0.92353892
105MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.91897830
106PU_27001747_Chip-Seq_BMDM_Mouse0.91509537
107SRF_21415370_ChIP-Seq_HL-1_Mouse0.91253248
108RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.90817405
109CIITA_25753668_ChIP-Seq_RAJI_Human0.90591747
110ELK1_19687146_ChIP-ChIP_HELA_Human0.90088561
111FLI1_21867929_ChIP-Seq_CD8_Mouse0.89265052
112CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.89092514
113HOXB4_20404135_ChIP-ChIP_EML_Mouse0.88908972
114ERG_20517297_ChIP-Seq_VCAP_Human0.88599930
115TP53_22573176_ChIP-Seq_HFKS_Human0.88418003
116CTCF_20526341_ChIP-Seq_ESCs_Human0.87924824
117PCGF2_27294783_Chip-Seq_NPCs_Mouse0.86183184
118AR_20517297_ChIP-Seq_VCAP_Human0.85507577
119EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84652408
120SA1_27219007_Chip-Seq_Bcells_Human0.83547573
121NCOR_22424771_ChIP-Seq_293T_Human0.83136511
122GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.81125785
123CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81080361
124BCOR_27268052_Chip-Seq_Bcells_Human0.81063509
125TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80534566
126YY1_21170310_ChIP-Seq_MESCs_Mouse0.79322294
127GATA3_26560356_Chip-Seq_TH1_Human0.78519254
128FLI1_27457419_Chip-Seq_LIVER_Mouse0.78146554
129BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.78081363
130NANOG_20526341_ChIP-Seq_ESCs_Human0.77876527
131GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.77810829
132GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.77561619
133PCGF2_27294783_Chip-Seq_ESCs_Mouse0.77210901
134CTCF_26484167_Chip-Seq_Bcells_Mouse0.74964980
135SA1_27219007_Chip-Seq_ERYTHROID_Human0.74861862
136EGR1_19032775_ChIP-ChIP_M12_Human0.74134566
137CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.73870004
138TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.73635860
139MYC_19079543_ChIP-ChIP_MESCs_Mouse0.73139200
140CTCF_21964334_Chip-Seq_Bcells_Human0.72695389
141DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.71914539
142YY1_22570637_ChIP-Seq_MALME-3M_Human0.70662485
143E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.69844180
144SPI1_20517297_ChIP-Seq_HL60_Human0.68736714
145P300_27268052_Chip-Seq_Bcells_Human0.66899197

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.47425731
2MP0005671_abnormal_response_to4.35432348
3MP0000685_abnormal_immune_system4.27985193
4MP0001800_abnormal_humoral_immune3.23399186
5MP0005000_abnormal_immune_tolerance3.09598000
6MP0005387_immune_system_phenotype3.03691547
7MP0001790_abnormal_immune_system3.03691547
8MP0001835_abnormal_antigen_presentation3.02553608
9MP0002420_abnormal_adaptive_immunity2.99500707
10MP0002398_abnormal_bone_marrow2.96218474
11MP0002166_altered_tumor_susceptibility2.95827666
12MP0001819_abnormal_immune_cell2.95437834
13MP0002723_abnormal_immune_serum2.93828736
14MP0003436_decreased_susceptibility_to2.91366890
15MP0009785_altered_susceptibility_to2.90200251
16MP0000703_abnormal_thymus_morphology2.84364527
17MP0003724_increased_susceptibility_to2.83442644
18MP0009333_abnormal_splenocyte_physiolog2.80180740
19MP0002405_respiratory_system_inflammati2.76463576
20MP0002452_abnormal_antigen_presenting2.63924879
21MP0002933_joint_inflammation2.56835249
22MP0005025_abnormal_response_to2.55327083
23MP0000716_abnormal_immune_system2.53616355
24MP0002006_tumorigenesis2.44396796
25MP0003866_abnormal_defecation2.37988143
26MP0002722_abnormal_immune_system2.37725619
27MP0001873_stomach_inflammation2.30910796
28MP0000689_abnormal_spleen_morphology2.29429584
29MP0004510_myositis2.27697134
30MP0010155_abnormal_intestine_physiology2.16673585
31MP0004947_skin_inflammation2.16529470
32MP0006082_CNS_inflammation2.09154392
33MP0002429_abnormal_blood_cell2.02598601
34MP0010234_abnormal_vibrissa_follicle1.98126220
35MP0002396_abnormal_hematopoietic_system1.95073024
36MP0002148_abnormal_hypersensitivity_rea1.85510858
37MP0003300_gastrointestinal_ulcer1.83331742
38MP0005464_abnormal_platelet_physiology1.81996774
39MP0002419_abnormal_innate_immunity1.78315165
40MP0003303_peritoneal_inflammation1.65715471
41MP0001845_abnormal_inflammatory_respons1.62293751
42MP0004381_abnormal_hair_follicle1.58042714
43MP0005075_abnormal_melanosome_morpholog1.56764634
44MP0001853_heart_inflammation1.56734260
45MP0009379_abnormal_foot_pigmentation1.41555670
46MP0005166_decreased_susceptibility_to1.39615638
47MP0001542_abnormal_bone_strength1.37385167
48MP0000858_altered_metastatic_potential1.34635205
49MP0004808_abnormal_hematopoietic_stem1.28213255
50MP0002168_other_aberrant_phenotype1.27941780
51MP0005310_abnormal_salivary_gland1.21264312
52MP0005174_abnormal_tail_pigmentation1.20694963
53MP0001905_abnormal_dopamine_level1.19692477
54MP0001919_abnormal_reproductive_system1.19611239
55MP0004145_abnormal_muscle_electrophysio1.19066163
56MP0003786_premature_aging1.15642811
57MP0006054_spinal_hemorrhage1.11357176
58MP0001533_abnormal_skeleton_physiology1.11350561
59MP0002102_abnormal_ear_morphology1.10029989
60MP0000569_abnormal_digit_pigmentation1.09622083
61MP0002138_abnormal_hepatobiliary_system1.08773056
62MP0008469_abnormal_protein_level1.05250885
63MP0000604_amyloidosis1.04304515
64MP0005023_abnormal_wound_healing1.01971814
65MP0005645_abnormal_hypothalamus_physiol0.99692786
66MP0003172_abnormal_lysosome_physiology0.98031160
67MP0003137_abnormal_impulse_conducting0.97547131
68MP0000465_gastrointestinal_hemorrhage0.95093866
69MP0002277_abnormal_respiratory_mucosa0.93878279
70MP0008961_abnormal_basal_metabolism0.91815725
71MP0001851_eye_inflammation0.91550157
72MP0003453_abnormal_keratinocyte_physiol0.90793820
73MP0002019_abnormal_tumor_incidence0.89438251
74MP0003448_altered_tumor_morphology0.88887348
75MP0003806_abnormal_nucleotide_metabolis0.87600281
76MP0008873_increased_physiological_sensi0.86526591
77MP0000372_irregular_coat_pigmentation0.85249405
78MP0009765_abnormal_xenobiotic_induced0.85085241
79MP0003329_amyloid_beta_deposits0.83668808
80MP0002998_abnormal_bone_remodeling0.75747632
81MP0003075_altered_response_to0.74128678
82MP0001666_abnormal_nutrient_absorption0.73873870
83MP0001348_abnormal_lacrimal_gland0.72171045
84MP0002009_preneoplasia0.70242375
85MP0000015_abnormal_ear_pigmentation0.67916874
86MP0003878_abnormal_ear_physiology0.67118605
87MP0005377_hearing/vestibular/ear_phenot0.67118605
88MP0009763_increased_sensitivity_to0.66624365
89MP0004742_abnormal_vestibular_system0.66534599
90MP0002132_abnormal_respiratory_system0.65774797
91MP0001243_abnormal_dermal_layer0.65485150
92MP0004883_abnormal_blood_vessel0.64291474
93MP0005389_reproductive_system_phenotype0.63684064
94MP0009643_abnormal_urine_homeostasis0.62886452
95MP0005623_abnormal_meninges_morphology0.61175393
96MP0002877_abnormal_melanocyte_morpholog0.60653555
97MP0001661_extended_life_span0.59560919
98MP0000609_abnormal_liver_physiology0.59483424
99MP0005330_cardiomyopathy0.59019037
100MP0000490_abnormal_crypts_of0.57712807
101MP0003795_abnormal_bone_structure0.56907151
102MP0006036_abnormal_mitochondrial_physio0.55615259
103MP0008789_abnormal_olfactory_epithelium0.55440615
104MP0000383_abnormal_hair_follicle0.54730685
105MP0005636_abnormal_mineral_homeostasis0.54293102
106MP0001984_abnormal_olfaction0.53397842
107MP0003045_fibrosis0.53238284
108MP0005395_other_phenotype0.52648947
109MP0002163_abnormal_gland_morphology0.52497511
110MP0002095_abnormal_skin_pigmentation0.49953033
111MP0001765_abnormal_ion_homeostasis0.49761227
112MP0008872_abnormal_physiological_respon0.48589824
113MP0004130_abnormal_muscle_cell0.48183959
114MP0002136_abnormal_kidney_physiology0.47770963
115MP0003567_abnormal_fetal_cardiomyocyte0.47258186
116MP0001663_abnormal_digestive_system0.46354603
117MP0003195_calcinosis0.45107338
118MP0002089_abnormal_postnatal_growth/wei0.45095314
119MP0003077_abnormal_cell_cycle0.44972861
120MP0008057_abnormal_DNA_replication0.44568564
121MP0000371_diluted_coat_color0.43936470
122MP0001968_abnormal_touch/_nociception0.43195219
123MP0003690_abnormal_glial_cell0.43165687
124MP0009764_decreased_sensitivity_to0.42418588
125MP0003633_abnormal_nervous_system0.40555436
126MP0002822_catalepsy0.40544375
127MP0000920_abnormal_myelination0.40093411
128MP0002693_abnormal_pancreas_physiology0.39824908
129MP0001216_abnormal_epidermal_layer0.39539257
130MP0000343_altered_response_to0.39448219
131MP0000249_abnormal_blood_vessel0.38843241
132MP0000477_abnormal_intestine_morphology0.38366463
133MP0000367_abnormal_coat/_hair0.38109849
134MP0004957_abnormal_blastocyst_morpholog0.37271888
135MP0000313_abnormal_cell_death0.35058869
136MP0008569_lethality_at_weaning0.33587347
137MP0005397_hematopoietic_system_phenotyp0.32553531
138MP0001545_abnormal_hematopoietic_system0.32553531
139MP0002083_premature_death0.31800425
140MP0001191_abnormal_skin_condition0.30923932
141MP0000377_abnormal_hair_follicle0.30512325

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)7.91819310
2T lymphocytopenia (HP:0005403)7.29036923
3Aplastic anemia (HP:0001915)7.27131361
4Abnormality of T cell number (HP:0011839)7.00860276
5Severe combined immunodeficiency (HP:0004430)6.75771856
6Combined immunodeficiency (HP:0005387)6.22058146
7Increased IgM level (HP:0003496)5.81650580
8Elevated erythrocyte sedimentation rate (HP:0003565)5.71381003
9Abnormality of T cells (HP:0002843)5.67886885
10IgM deficiency (HP:0002850)5.60283503
11Eczematoid dermatitis (HP:0000976)5.52899551
12IgG deficiency (HP:0004315)5.51807600
13Hypoproteinemia (HP:0003075)5.48176389
14Panhypogammaglobulinemia (HP:0003139)5.17874144
15Recurrent bronchitis (HP:0002837)4.88545319
16Myositis (HP:0100614)4.81316216
17Recurrent fungal infections (HP:0002841)4.65339985
18Abnormality of T cell physiology (HP:0011840)4.20968056
19Abnormality of macrophages (HP:0004311)4.14106484
20Pustule (HP:0200039)4.01202254
21IgA deficiency (HP:0002720)3.91712448
22Retrobulbar optic neuritis (HP:0100654)3.89099558
23Optic neuritis (HP:0100653)3.89099558
24Joint swelling (HP:0001386)3.85988473
25Recurrent viral infections (HP:0004429)3.70929731
26Chronic diarrhea (HP:0002028)3.70439679
27Abnormality of the prostate (HP:0008775)3.67408397
28Recurrent cutaneous fungal infections (HP:0011370)3.66766274
29Chronic mucocutaneous candidiasis (HP:0002728)3.66766274
30Nasal polyposis (HP:0100582)3.64493491
31Abnormality of eosinophils (HP:0001879)3.57234013
32B lymphocytopenia (HP:0010976)3.49897484
33Abnormality of B cell number (HP:0010975)3.49897484
34Hemiplegia (HP:0002301)3.39680618
35Eosinophilia (HP:0001880)3.37907255
36Lymphopenia (HP:0001888)3.35108395
37Autoimmune hemolytic anemia (HP:0001890)3.34414917
38Orchitis (HP:0100796)3.31781946
39Leukocytosis (HP:0001974)3.29415998
40Chronic otitis media (HP:0000389)3.22498650
41Abnormality of cells of the lymphoid lineage (HP:0012140)3.21757388
42Recurrent sinusitis (HP:0011108)3.11891576
43Hypergammaglobulinemia (HP:0010702)3.10882935
44Abnormal albumin level (HP:0012116)3.05479794
45Hypoalbuminemia (HP:0003073)3.05479794
463-Methylglutaconic aciduria (HP:0003535)3.04562133
47Abnormality of the nasal mucosa (HP:0000433)3.03856808
48Thrombocytosis (HP:0001894)3.02145945
49Renal Fanconi syndrome (HP:0001994)3.01590691
50Increased intramyocellular lipid droplets (HP:0012240)2.96726336
51Generalized aminoaciduria (HP:0002909)2.94295438
52Granulocytopenia (HP:0001913)2.91758094
53Recurrent skin infections (HP:0001581)2.91037049
54Pancytopenia (HP:0001876)2.88510792
55Chest pain (HP:0100749)2.87286593
56Hemoptysis (HP:0002105)2.80730382
57Thyroiditis (HP:0100646)2.78931199
58Abnormal delayed hypersensitivity skin test (HP:0002963)2.78236419
59Pulmonary infiltrates (HP:0002113)2.77079750
60Hypoplasia of the thymus (HP:0000778)2.76872170
61Meningitis (HP:0001287)2.75411707
62Vasculitis (HP:0002633)2.74889633
63Bronchitis (HP:0012387)2.71898136
64Mitochondrial inheritance (HP:0001427)2.67337578
65Keratoconjunctivitis sicca (HP:0001097)2.66311106
66Recurrent abscess formation (HP:0002722)2.60284540
67Lymphoma (HP:0002665)2.55593010
68Hepatocellular necrosis (HP:0001404)2.53466056
69Oral leukoplakia (HP:0002745)2.52686719
70Gingivitis (HP:0000230)2.51928130
71Gastrointestinal infarctions (HP:0005244)2.50319553
72Encephalitis (HP:0002383)2.45520900
73Mediastinal lymphadenopathy (HP:0100721)2.44323282
74Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.43965485
75Decreased activity of mitochondrial respiratory chain (HP:0008972)2.43965485
76Congenital stationary night blindness (HP:0007642)2.42705423
77Acute hepatic failure (HP:0006554)2.40168754
78Abnormality of the fingertips (HP:0001211)2.40062355
79Increased muscle lipid content (HP:0009058)2.39118935
80Keratoconjunctivitis (HP:0001096)2.38397399
81Reticulocytopenia (HP:0001896)2.33843205
82Recurrent otitis media (HP:0000403)2.33493377
83Abnormality of the pleura (HP:0002103)2.29783844
84Inflammation of the large intestine (HP:0002037)2.29474247
85Amyotrophic lateral sclerosis (HP:0007354)2.25270509
86Severe visual impairment (HP:0001141)2.24060168
87Autoimmune thrombocytopenia (HP:0001973)2.23047083
88Arterial thrombosis (HP:0004420)2.22019421
89Hyponatremia (HP:0002902)2.21638625
9011 pairs of ribs (HP:0000878)2.20646061
91Basal cell carcinoma (HP:0002671)2.19062137
92Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.18068175
93Gastrointestinal inflammation (HP:0004386)2.17245459
94Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16267813
95Pulmonary embolism (HP:0002204)2.14140615
96Abnormal mitochondria in muscle tissue (HP:0008316)2.13375761
97Hepatic necrosis (HP:0002605)2.11145982
98Abnormality of male internal genitalia (HP:0000022)2.10690327
99Renal cortical cysts (HP:0000803)2.09383520
100Increased hepatocellular lipid droplets (HP:0006565)2.08178638
101Hepatitis (HP:0012115)2.06966243
102Obstructive lung disease (HP:0006536)2.06797306
103Chronic obstructive pulmonary disease (HP:0006510)2.06797306
104Increased density of long bones (HP:0006392)2.01801165
105Acute necrotizing encephalopathy (HP:0006965)1.99696983
106Gastrointestinal stroma tumor (HP:0100723)1.99022699
107Increased IgE level (HP:0003212)1.96869066
108Increased CSF lactate (HP:0002490)1.96492806
109Decreased electroretinogram (ERG) amplitude (HP:0000654)1.94956602
110Skin rash (HP:0000988)1.93336958
111Large eyes (HP:0001090)1.93316027
112Agammaglobulinemia (HP:0004432)1.92784032
113Multiple enchondromatosis (HP:0005701)1.90582618
114Epistaxis (HP:0000421)1.90250761
115Ureteral stenosis (HP:0000071)1.88180342
116Increased serum ferritin (HP:0003281)1.87942473
117Arthralgia (HP:0002829)1.87585271
118Cheilitis (HP:0100825)1.87404599
119Gingival bleeding (HP:0000225)1.87135726
120Cellular immunodeficiency (HP:0005374)1.85456026
121Spontaneous hematomas (HP:0007420)1.85136191
122Abnormality of the endocardium (HP:0004306)1.84607012
123Skin ulcer (HP:0200042)1.82360099
124Gangrene (HP:0100758)1.82294934
125Petechiae (HP:0000967)1.82130356
126Abnormality of the pericardium (HP:0001697)1.78582835
127Abnormal rod and cone electroretinograms (HP:0008323)1.77742677
128Emphysema (HP:0002097)1.77579156
129Papilloma (HP:0012740)1.76918712
130Verrucae (HP:0200043)1.76918712
131Ragged-red muscle fibers (HP:0003200)1.76548507
132Pigmentary retinal degeneration (HP:0001146)1.75040169
133Prolonged bleeding time (HP:0003010)1.74435480
134Pulmonary fibrosis (HP:0002206)1.73194492
135Anorexia (HP:0002039)1.72318949
136Distal arthrogryposis (HP:0005684)1.71654450
137Recurrent bacterial skin infections (HP:0005406)1.69915389
138Atrophy/Degeneration involving motor neurons (HP:0007373)1.66729016
139Ureteral obstruction (HP:0006000)1.64799208
140Bronchiectasis (HP:0002110)1.64653029
141Restrictive lung disease (HP:0002091)1.64645736

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.59933172
2MAP4K16.53425345
3ZAP704.58053462
4MAP3K123.92584154
5TESK23.79377628
6ITK2.80211208
7BCKDK2.78693993
8KDR2.46468463
9JAK32.44013948
10FGFR42.40358861
11SRPK12.30242255
12IKBKE1.98779275
13LCK1.95075523
14TAOK31.91675025
15TYK21.88959239
16STK101.79368496
17TESK11.79030630
18SIK31.66871031
19NLK1.64861728
20TEC1.56748640
21GRK61.50867406
22SYK1.45771406
23MYLK1.45761639
24CSK1.42895973
25MAP3K141.42289428
26VRK11.38590869
27BUB11.37760511
28MAP3K111.37186506
29MAPKAPK31.35957884
30VRK21.34875427
31JAK11.27553156
32SIK21.19727233
33FGFR31.17996333
34HCK1.17708837
35ADRBK21.17687583
36ZAK1.16644427
37CAMKK21.16036302
38GRK71.13990402
39LIMK11.12321094
40BTK1.11148253
41NME21.09413502
42PRKCQ1.05995598
43TBK10.98795306
44FGFR10.96727302
45MAP2K60.93009009
46EEF2K0.88920949
47PKN20.87237563
48MARK30.86366886
49GRK10.86175953
50SIK10.86120329
51PRKCH0.85999195
52MAP3K130.84995728
53DAPK10.84968458
54IKBKB0.82670073
55MAP3K100.80055580
56LRRK20.79485838
57LYN0.77689067
58MST40.76764497
59PDGFRB0.75217245
60BLK0.71035862
61RPS6KA40.69941733
62CHUK0.67945245
63DAPK20.66340383
64MARK20.66128857
65NME10.65162400
66ROCK10.63355478
67MAP3K70.61964193
68STK240.60241792
69JAK20.60020078
70CAMKK10.59981286
71FYN0.59206872
72EIF2AK10.57706100
73KIT0.55885125
74ILK0.54787473
75AURKA0.53792233
76SCYL20.50997489
77TAOK10.50895090
78RIPK40.50165223
79PASK0.49661086
80INSR0.49218300
81PINK10.48984912
82MAP2K30.48858719
83TIE10.47965595
84TRPM70.47289874
85MAP4K20.46970570
86ROCK20.46676588
87TLK10.46523828
88CLK10.45230942
89PIM10.43647677
90CDK190.43158654
91DAPK30.42449514
92TSSK60.41969347
93PAK40.40858604
94IRAK40.40414250
95TRIB30.40313018
96FRK0.39987770
97WNK40.39835186
98FES0.39157138
99STK160.38595775
100OBSCN0.37310629
101PIK3CG0.36187437
102MAP3K10.35904737
103EIF2AK30.35363990
104INSRR0.34754455
105TYRO30.34249193
106PAK10.33625249
107IGF1R0.33103794
108PRKCA0.32510972
109TNK20.32323221
110EPHA30.31776597
111PIM20.29052932
112MAP2K70.28611736
113MATK0.27548678
114MAPK110.26867832
115TGFBR20.25495543
116RPS6KA50.25152757
117CAMK2A0.24773999
118OXSR10.24206911
119MAPKAPK20.24162413
120CSNK1A10.23871090
121TTN0.23657412
122EPHB10.23168802
123PTK20.22840651
124ATR0.22797475
125ERBB30.21782456
126ALK0.21606377
127NEK60.21559279
128SRC0.21405223
129HIPK20.21014318
130CDK120.20759661
131MAPK130.20234164
132PRKCB0.20108390
133MUSK0.20020895
134RAF10.19855854
135PDK10.19286140
136PRKACA0.19278545
137PRKCD0.19267465
138CSF1R0.19159868
139MAP3K80.18953621
140MAPK30.18928153
141MAP3K50.18743730
142CSNK1G30.18665247
143EGFR0.18258333
144ABL10.16376960
145DMPK0.15819538
146NTRK20.15603410
147TGFBR10.13961311

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.57787248
2T cell receptor signaling pathway_Homo sapiens_hsa046604.44059928
3Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.69391512
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.52959059
5Allograft rejection_Homo sapiens_hsa053303.09258365
6Graft-versus-host disease_Homo sapiens_hsa053323.08711162
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053213.07084304
8NF-kappa B signaling pathway_Homo sapiens_hsa040643.00270503
9Antigen processing and presentation_Homo sapiens_hsa046122.74898571
10Hematopoietic cell lineage_Homo sapiens_hsa046402.74391205
11Measles_Homo sapiens_hsa051622.57958183
12Oxidative phosphorylation_Homo sapiens_hsa001902.42229906
13Autoimmune thyroid disease_Homo sapiens_hsa053202.32438267
14Parkinsons disease_Homo sapiens_hsa050122.15622953
15Viral myocarditis_Homo sapiens_hsa054162.03870065
16Ribosome_Homo sapiens_hsa030102.00742434
17Osteoclast differentiation_Homo sapiens_hsa043801.75124871
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.65392484
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.64580527
20Leishmaniasis_Homo sapiens_hsa051401.59933204
21Asthma_Homo sapiens_hsa053101.59688453
22Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.50076146
23Alzheimers disease_Homo sapiens_hsa050101.46429945
24Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.32625133
25Type I diabetes mellitus_Homo sapiens_hsa049401.31723895
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.31652008
27Herpes simplex infection_Homo sapiens_hsa051681.29152699
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.28836803
29B cell receptor signaling pathway_Homo sapiens_hsa046621.27103850
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.24208721
31Chemokine signaling pathway_Homo sapiens_hsa040621.24052648
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.22838085
33Toxoplasmosis_Homo sapiens_hsa051451.22746285
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.20314446
35Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.18513914
36Acute myeloid leukemia_Homo sapiens_hsa052211.14555443
37Hepatitis B_Homo sapiens_hsa051611.10505567
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08911974
39Cardiac muscle contraction_Homo sapiens_hsa042601.08311385
40Huntingtons disease_Homo sapiens_hsa050161.07163379
41Shigellosis_Homo sapiens_hsa051311.01372598
42HTLV-I infection_Homo sapiens_hsa051661.00533013
43NOD-like receptor signaling pathway_Homo sapiens_hsa046210.94163600
44TNF signaling pathway_Homo sapiens_hsa046680.93048498
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.92877067
46SNARE interactions in vesicular transport_Homo sapiens_hsa041300.90022770
47Nitrogen metabolism_Homo sapiens_hsa009100.89200729
48Staphylococcus aureus infection_Homo sapiens_hsa051500.88734458
49Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.87529582
50Prolactin signaling pathway_Homo sapiens_hsa049170.81147399
51Spliceosome_Homo sapiens_hsa030400.79091047
52Toll-like receptor signaling pathway_Homo sapiens_hsa046200.79071418
53VEGF signaling pathway_Homo sapiens_hsa043700.78374061
54Malaria_Homo sapiens_hsa051440.76577331
55Platelet activation_Homo sapiens_hsa046110.76530767
56Epstein-Barr virus infection_Homo sapiens_hsa051690.74669546
57Apoptosis_Homo sapiens_hsa042100.73183539
58Legionellosis_Homo sapiens_hsa051340.72004714
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70124729
60Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.69342423
61Pancreatic cancer_Homo sapiens_hsa052120.66537433
62Influenza A_Homo sapiens_hsa051640.66469506
63Phototransduction_Homo sapiens_hsa047440.66267243
64RNA degradation_Homo sapiens_hsa030180.65835922
65Colorectal cancer_Homo sapiens_hsa052100.63811343
66Viral carcinogenesis_Homo sapiens_hsa052030.62261065
67Hepatitis C_Homo sapiens_hsa051600.60130972
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.60106571
69Systemic lupus erythematosus_Homo sapiens_hsa053220.57152161
70Steroid biosynthesis_Homo sapiens_hsa001000.55522535
71Thyroid cancer_Homo sapiens_hsa052160.55488767
72Endocytosis_Homo sapiens_hsa041440.54109040
73Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51465277
74Peroxisome_Homo sapiens_hsa041460.51356931
75Rheumatoid arthritis_Homo sapiens_hsa053230.50373258
76Salmonella infection_Homo sapiens_hsa051320.50357812
77Rap1 signaling pathway_Homo sapiens_hsa040150.48872101
78Chronic myeloid leukemia_Homo sapiens_hsa052200.48280829
79Pertussis_Homo sapiens_hsa051330.47324716
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43816907
81Tuberculosis_Homo sapiens_hsa051520.43442749
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.41932926
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40787272
84Small cell lung cancer_Homo sapiens_hsa052220.40740585
85Prion diseases_Homo sapiens_hsa050200.40572574
86Insulin resistance_Homo sapiens_hsa049310.39753370
87p53 signaling pathway_Homo sapiens_hsa041150.38603280
88Drug metabolism - other enzymes_Homo sapiens_hsa009830.37597265
89mRNA surveillance pathway_Homo sapiens_hsa030150.36811734
90African trypanosomiasis_Homo sapiens_hsa051430.34789240
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.34667658
92Proteasome_Homo sapiens_hsa030500.30340275
93RNA polymerase_Homo sapiens_hsa030200.30279196
94Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.29692293
95MAPK signaling pathway_Homo sapiens_hsa040100.29318101
96Fanconi anemia pathway_Homo sapiens_hsa034600.28658986
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28569929
98Pyrimidine metabolism_Homo sapiens_hsa002400.28510825
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.28460659
100Collecting duct acid secretion_Homo sapiens_hsa049660.26337434
101Selenocompound metabolism_Homo sapiens_hsa004500.26132442
102Taste transduction_Homo sapiens_hsa047420.25658447
103Propanoate metabolism_Homo sapiens_hsa006400.25489064
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.24979266
105Butanoate metabolism_Homo sapiens_hsa006500.24360722
106RNA transport_Homo sapiens_hsa030130.23320653
107Nucleotide excision repair_Homo sapiens_hsa034200.23099559
108Retinol metabolism_Homo sapiens_hsa008300.22953980
109alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.20955067
110Protein export_Homo sapiens_hsa030600.20188510
111Phagosome_Homo sapiens_hsa041450.19804164
112Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.19290887
113Sulfur metabolism_Homo sapiens_hsa009200.18967180
114Cyanoamino acid metabolism_Homo sapiens_hsa004600.18030925
115Olfactory transduction_Homo sapiens_hsa047400.17623626
116DNA replication_Homo sapiens_hsa030300.16366961
117Phosphatidylinositol signaling system_Homo sapiens_hsa040700.15998330
118Non-small cell lung cancer_Homo sapiens_hsa052230.15465083
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.15372620
120Circadian rhythm_Homo sapiens_hsa047100.15175787
121Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.14267333
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.13936722
123Ras signaling pathway_Homo sapiens_hsa040140.13593575
124Homologous recombination_Homo sapiens_hsa034400.13438893
125FoxO signaling pathway_Homo sapiens_hsa040680.12759366
126Pathways in cancer_Homo sapiens_hsa052000.11598984
127Notch signaling pathway_Homo sapiens_hsa043300.11016111
128Alcoholism_Homo sapiens_hsa050340.10583555
129N-Glycan biosynthesis_Homo sapiens_hsa005100.09595205
130mTOR signaling pathway_Homo sapiens_hsa041500.08632735
131Prostate cancer_Homo sapiens_hsa052150.08253860
132Purine metabolism_Homo sapiens_hsa002300.08148611
133Renal cell carcinoma_Homo sapiens_hsa052110.08044803
134Linoleic acid metabolism_Homo sapiens_hsa005910.07021076
135Vibrio cholerae infection_Homo sapiens_hsa051100.06711809
136Lysosome_Homo sapiens_hsa041420.05539389
137Non-homologous end-joining_Homo sapiens_hsa034500.05186073
138HIF-1 signaling pathway_Homo sapiens_hsa040660.04023289
139One carbon pool by folate_Homo sapiens_hsa006700.02715853
140Focal adhesion_Homo sapiens_hsa045100.02579665

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »