TRAV13-2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive thymic T cell selection (GO:0045059)9.08363526
2positive T cell selection (GO:0043368)8.58590493
3negative T cell selection (GO:0043383)8.47309614
4cytidine deamination (GO:0009972)8.25264941
5cytidine metabolic process (GO:0046087)8.25264941
6cytidine catabolic process (GO:0006216)8.25264941
7negative thymic T cell selection (GO:0045060)8.03217700
8thymic T cell selection (GO:0045061)7.85838648
9pyrimidine ribonucleoside catabolic process (GO:0046133)7.54595770
10T cell selection (GO:0045058)7.37277047
11regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450917.02879893
12positive regulation of gamma-delta T cell activation (GO:0046645)7.02668436
13positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.70197114
14leukocyte aggregation (GO:0070486)6.67971296
15DNA deamination (GO:0045006)6.61579406
16regulation of gamma-delta T cell differentiation (GO:0045586)6.41030082
17positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.36116516
18negative regulation of cell killing (GO:0031342)6.24024944
19negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.24024944
20NIK/NF-kappaB signaling (GO:0038061)6.09320130
21antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.04941897
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.04941897
23regulation of gamma-delta T cell activation (GO:0046643)5.64795045
24regulation of isotype switching to IgG isotypes (GO:0048302)5.64164223
25T cell receptor signaling pathway (GO:0050852)5.40525953
26response to interleukin-15 (GO:0070672)5.29848641
27regulation of T cell tolerance induction (GO:0002664)5.28621124
28T cell migration (GO:0072678)5.24529759
29interferon-gamma production (GO:0032609)5.04616726
30cellular response to interleukin-15 (GO:0071350)5.03857495
31antigen processing and presentation of endogenous antigen (GO:0019883)4.99056712
32regulation of interleukin-12 biosynthetic process (GO:0045075)4.86873532
33regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.85799940
34T cell costimulation (GO:0031295)4.70485380
35lymphocyte costimulation (GO:0031294)4.60676779
36negative regulation by host of viral transcription (GO:0043922)4.58150269
37positive regulation of interleukin-2 production (GO:0032743)4.57941682
38regulation of alpha-beta T cell proliferation (GO:0046640)4.55541866
39activated T cell proliferation (GO:0050798)4.55237512
40regulation of interleukin-2 biosynthetic process (GO:0045076)4.47499229
41antigen receptor-mediated signaling pathway (GO:0050851)4.33054541
42regulation of regulatory T cell differentiation (GO:0045589)4.30598297
43regulation of B cell receptor signaling pathway (GO:0050855)4.30481507
44positive regulation of interleukin-1 beta secretion (GO:0050718)4.30233179
45positive regulation of tolerance induction (GO:0002645)4.26847533
46positive regulation of alpha-beta T cell proliferation (GO:0046641)4.23926245
47positive regulation of interleukin-4 production (GO:0032753)4.15177388
48regulation of interleukin-1 beta secretion (GO:0050706)4.10728132
49positive regulation of interleukin-1 secretion (GO:0050716)4.05410938
50negative regulation of viral genome replication (GO:0045071)4.04748577
51regulation of T cell receptor signaling pathway (GO:0050856)4.04139758
52regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.01914664
53positive regulation of calcium-mediated signaling (GO:0050850)4.00902345
54regulation of lymphocyte chemotaxis (GO:1901623)3.98949519
55positive regulation of B cell differentiation (GO:0045579)3.94932978
56eosinophil chemotaxis (GO:0048245)3.93558208
57lymphocyte chemotaxis (GO:0048247)3.92654822
58positive regulation of T cell differentiation (GO:0045582)3.77651032
59positive regulation of humoral immune response (GO:0002922)3.77060699
60regulation of interleukin-13 production (GO:0032656)3.73696302
61regulation of interleukin-4 production (GO:0032673)3.73694862
62type I interferon signaling pathway (GO:0060337)3.69505839
63cellular response to type I interferon (GO:0071357)3.69505839
64negative regulation of T cell apoptotic process (GO:0070233)3.66183709
65regulation of tolerance induction (GO:0002643)3.66182275
66pyrimidine nucleoside catabolic process (GO:0046135)3.63847085
67response to type I interferon (GO:0034340)3.63805884
68regulation of interleukin-1 secretion (GO:0050704)3.63389520
69positive regulation of defense response to virus by host (GO:0002230)3.59817537
70positive regulation of isotype switching (GO:0045830)3.58935024
71desmosome organization (GO:0002934)3.56803218
72T cell differentiation (GO:0030217)3.52509082
73eosinophil migration (GO:0072677)3.52434213
74regulation of interleukin-2 production (GO:0032663)3.52177587
75detection of bacterium (GO:0016045)3.51101272
76negative regulation of T cell mediated immunity (GO:0002710)3.51017875
77regulation of T cell mediated cytotoxicity (GO:0001914)3.49604759
78alpha-beta T cell differentiation (GO:0046632)3.48432031
79tolerance induction (GO:0002507)3.46425458
80positive regulation of T cell mediated cytotoxicity (GO:0001916)3.45165886
81production of molecular mediator involved in inflammatory response (GO:0002532)3.44557458
82omega-hydroxylase P450 pathway (GO:0097267)3.42161659
83positive regulation of lymphocyte migration (GO:2000403)3.40881294
84positive regulation of DNA recombination (GO:0045911)3.40693149
85positive regulation of granulocyte differentiation (GO:0030854)3.40146575
86alpha-beta T cell activation (GO:0046631)3.38647141
87positive regulation of interleukin-1 beta production (GO:0032731)3.38295896
88positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.36524978
89mast cell activation (GO:0045576)3.36482569
90leukocyte cell-cell adhesion (GO:0007159)3.35573813
91Arp2/3 complex-mediated actin nucleation (GO:0034314)3.32800278
92regulation of defense response to virus by virus (GO:0050690)3.32618860
93regulation of T cell differentiation (GO:0045580)3.32015302
94positive regulation of T cell cytokine production (GO:0002726)3.30800465
95negative regulation of viral transcription (GO:0032897)3.28838989
96lymphocyte migration (GO:0072676)3.26504008
97regulation of leukocyte mediated cytotoxicity (GO:0001910)3.25674362
98positive regulation of lymphocyte differentiation (GO:0045621)3.24243425
99negative regulation of T cell receptor signaling pathway (GO:0050860)3.23989338
100positive regulation of T cell activation (GO:0050870)3.22378031
101positive regulation of macrophage differentiation (GO:0045651)3.21462087
102granulocyte activation (GO:0036230)3.21271905
103positive regulation of immunoglobulin mediated immune response (GO:0002891)3.20523139
104positive regulation of B cell mediated immunity (GO:0002714)3.20523139
105JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.19304769
106positive regulation of natural killer cell differentiation (GO:0032825)3.18373066
107T cell activation (GO:0042110)3.18328372
108regulation of isotype switching (GO:0045191)3.17715786
109chemokine-mediated signaling pathway (GO:0070098)3.17584314
110response to interferon-beta (GO:0035456)3.17254829
111regulation of cell killing (GO:0031341)3.16516718
112heterotypic cell-cell adhesion (GO:0034113)3.16394952
113regulation of viral genome replication (GO:0045069)3.15656322
114antigen processing and presentation via MHC class Ib (GO:0002475)3.13135530
115regulation of alpha-beta T cell activation (GO:0046634)3.12813513
116lymph node development (GO:0048535)3.12529821
117antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.10583693
118regulation of immunoglobulin mediated immune response (GO:0002889)3.08861501
119cellular response to interleukin-4 (GO:0071353)3.07802724
120positive regulation of cell killing (GO:0031343)3.05378561
121cellular defense response (GO:0006968)3.04379212
122negative regulation of leukocyte mediated immunity (GO:0002704)3.03285946
123T cell apoptotic process (GO:0070231)3.02560705
124positive regulation of interleukin-1 production (GO:0032732)3.02182288
125negative regulation of viral process (GO:0048525)3.02103811
126regulation of natural killer cell differentiation (GO:0032823)3.01076857
127interleukin-1-mediated signaling pathway (GO:0070498)3.00799004
128negative regulation of lymphocyte mediated immunity (GO:0002707)3.00192869
129regulation of B cell mediated immunity (GO:0002712)2.97944392
130regulation of immunoglobulin production (GO:0002637)2.96985502
131hypothalamus development (GO:0021854)2.96205094
132regulation of T cell activation (GO:0050863)2.93831952
133positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.92723068
134regulation of T cell cytokine production (GO:0002724)2.91008344
135T cell homeostasis (GO:0043029)2.89992004
136immune response-activating cell surface receptor signaling pathway (GO:0002429)2.88668881
137detection of other organism (GO:0098543)2.87460137
138positive regulation of alpha-beta T cell activation (GO:0046635)2.86190104
139positive regulation of natural killer cell mediated immunity (GO:0002717)2.84932228
140positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.84932228
141positive regulation of immunoglobulin production (GO:0002639)2.84872148
142regulation of alpha-beta T cell differentiation (GO:0046637)2.84573152
143regulation of lymphocyte differentiation (GO:0045619)2.84015065
144regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.82764340
145regulation of natural killer cell mediated immunity (GO:0002715)2.82764340
146regulation of B cell differentiation (GO:0045577)2.82219552
147response to interleukin-4 (GO:0070670)2.80517777
148negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.80027309

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.12823335
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human7.04218078
3MYC_22102868_ChIP-Seq_BL_Human4.02347332
4RUNX_20019798_ChIP-Seq_JUKART_Human3.95300538
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.93326733
6FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.86676666
7STAT4_19710469_ChIP-ChIP_TH1__Mouse3.35706446
8MYB_26560356_Chip-Seq_TH2_Human3.28025536
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.11937275
10UTX_26944678_Chip-Seq_JUKART_Human3.10976455
11E2F7_22180533_ChIP-Seq_HELA_Human3.08743757
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.08717946
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.08166229
14MAF_26560356_Chip-Seq_TH1_Human3.06391619
15MYB_26560356_Chip-Seq_TH1_Human2.92336207
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.86599011
17BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.83046623
18IRF8_22096565_ChIP-ChIP_GC-B_Human2.74214018
19MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.51970414
20KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.39449880
21VDR_21846776_ChIP-Seq_THP-1_Human2.39323567
22NOTCH1_21737748_ChIP-Seq_TLL_Human2.38614810
23VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.27914685
24MAF_26560356_Chip-Seq_TH2_Human2.17821350
25KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.14597873
26KDM2B_26808549_Chip-Seq_SUP-B15_Human2.05042391
27RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.03305579
28BP1_19119308_ChIP-ChIP_Hs578T_Human10.2713836
29KDM2B_26808549_Chip-Seq_DND41_Human1.99167886
30GATA3_27048872_Chip-Seq_THYMUS_Human1.97504502
31TCF7_22412390_ChIP-Seq_EML_Mouse1.91497908
32TP63_17297297_ChIP-ChIP_HaCaT_Human1.90222388
33E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.89959204
34VDR_24763502_ChIP-Seq_THP-1_Human1.88903897
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.79145735
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.73068033
37SMAD_19615063_ChIP-ChIP_OVARY_Human1.71234001
38KDM2B_26808549_Chip-Seq_JURKAT_Human1.67105517
39STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64729339
40SPI1_23547873_ChIP-Seq_NB4_Human1.61611034
41ELK3_25401928_ChIP-Seq_HUVEC_Human1.59940849
42RUNX1_22412390_ChIP-Seq_EML_Mouse1.56030585
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.51493402
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.47794227
45VDR_23849224_ChIP-Seq_CD4+_Human1.46560423
46CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.45266361
47RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.44244675
48MYB_21317192_ChIP-Seq_ERMYB_Mouse1.41511287
49NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41426886
50RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.38242482
51IRF8_27001747_Chip-Seq_BMDM_Mouse1.38003428
52GATA1_22025678_ChIP-Seq_K562_Human1.36618596
53SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.32315875
54NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.32065262
55TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.31658248
56FOXP3_21729870_ChIP-Seq_TREG_Human1.28875503
57SCL_19346495_ChIP-Seq_HPC-7_Human1.25819401
58LXR_22292898_ChIP-Seq_THP-1_Human1.24229067
59SPI1_23127762_ChIP-Seq_K562_Human1.23018275
60SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.22963773
61CIITA_25753668_ChIP-Seq_RAJI_Human1.20758167
62IRF8_21731497_ChIP-ChIP_J774_Mouse1.19909454
63BRD4_27068464_Chip-Seq_AML-cells_Mouse1.19366599
64HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17671125
65NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.17548306
66GABP_17652178_ChIP-ChIP_JURKAT_Human1.16964586
67GATA3_26560356_Chip-Seq_TH2_Human1.15971796
68TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13418195
69NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.11754740
70ELF1_17652178_ChIP-ChIP_JURKAT_Human1.10874846
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10672035
72RACK7_27058665_Chip-Seq_MCF-7_Human1.08522581
73LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.08116609
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07127518
75ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06619157
76CTCF_21964334_ChIP-Seq_BJAB-B_Human1.06288221
77RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.05545198
78MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.01593373
79SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human1.00533184
80ETS1_21867929_ChIP-Seq_TH2_Mouse1.00126654
81EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98050819
82CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97290878
83LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96694363
84TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94855212
85TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.93873116
86EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.93657634
87GATA1_19941827_ChIP-Seq_MEL_Mouse0.91008423
88PU_27001747_Chip-Seq_BMDM_Mouse0.90347803
89FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89559569
90CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87838762
91CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86998084
92VDR_24787735_ChIP-Seq_THP-1_Human0.86771109
93PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86612176
94CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86609732
95SRY_22984422_ChIP-ChIP_TESTIS_Rat0.85986149
96SA1_27219007_Chip-Seq_ERYTHROID_Human0.83863698
97P300_27268052_Chip-Seq_Bcells_Human0.83583332
98ELF5_23300383_ChIP-Seq_T47D_Human0.83297722
99CTCF_21964334_Chip-Seq_Bcells_Human0.82474138
100GATA2_22383799_ChIP-Seq_G1ME_Mouse0.81631291
101TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.81428266
102FLI1_27457419_Chip-Seq_LIVER_Mouse0.81195586
103FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79932901
104GATA3_26560356_Chip-Seq_TH1_Human0.79289181
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.79180519
106KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.79134787
107SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78668533
108IRF1_19129219_ChIP-ChIP_H3396_Human0.78360796
109PU.1_20513432_ChIP-Seq_Bcells_Mouse0.76974088
110FOXO3_23340844_ChIP-Seq_DLD1_Human0.76564198
111WT1_19549856_ChIP-ChIP_CCG9911_Human0.76476441
112KDM5A_27292631_Chip-Seq_BREAST_Human0.76264839
113ATF3_27146783_Chip-Seq_COLON_Human0.76072953
114GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.75570795
115CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.74780864
116MYC_19079543_ChIP-ChIP_MESCs_Mouse0.74612808
117FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.74517025
118VDR_22108803_ChIP-Seq_LS180_Human0.74344639
119RUNX1_27514584_Chip-Seq_MCF-7_Human0.73801160
120CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.72729919
121PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.72309149
122BCL6_27268052_Chip-Seq_Bcells_Human0.71613987
123EST1_17652178_ChIP-ChIP_JURKAT_Human0.70148703
124RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.69224996
125PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.68327724
126EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.66670716
127GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.66281098
128PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.64697381
129GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.63709494
130PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.63634820
131SMRT_27268052_Chip-Seq_Bcells_Human0.62829248
132Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.62193893
133JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.62034173
134BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.58317388
135SPI1_20517297_ChIP-Seq_HL60_Human0.56771003
136CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.55625599

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology5.86369679
2MP0005671_abnormal_response_to3.48856870
3MP0005645_abnormal_hypothalamus_physiol3.26838464
4MP0000569_abnormal_digit_pigmentation2.99661464
5MP0003724_increased_susceptibility_to2.95938923
6MP0000685_abnormal_immune_system2.84033688
7MP0002166_altered_tumor_susceptibility2.73529592
8MP0001800_abnormal_humoral_immune2.69914595
9MP0003436_decreased_susceptibility_to2.66729956
10MP0000703_abnormal_thymus_morphology2.62759690
11MP0004947_skin_inflammation2.57906597
12MP0003866_abnormal_defecation2.57288932
13MP0001727_abnormal_embryo_implantation2.55020302
14MP0005000_abnormal_immune_tolerance2.49772800
15MP0001790_abnormal_immune_system2.42918036
16MP0005387_immune_system_phenotype2.42918036
17MP0002398_abnormal_bone_marrow2.42201980
18MP0002420_abnormal_adaptive_immunity2.38079128
19MP0002723_abnormal_immune_serum2.37086358
20MP0004381_abnormal_hair_follicle2.36054868
21MP0001819_abnormal_immune_cell2.35421969
22MP0009333_abnormal_splenocyte_physiolog2.30181253
23MP0002006_tumorigenesis2.22566227
24MP0010234_abnormal_vibrissa_follicle2.21096443
25MP0000383_abnormal_hair_follicle2.20468097
26MP0002722_abnormal_immune_system2.19344765
27MP0002396_abnormal_hematopoietic_system2.14857359
28MP0002405_respiratory_system_inflammati2.08625554
29MP0002452_abnormal_antigen_presenting2.08619740
30MP0003705_abnormal_hypodermis_morpholog2.08430192
31MP0000716_abnormal_immune_system2.05457233
32MP0003303_peritoneal_inflammation2.02609224
33MP0002277_abnormal_respiratory_mucosa2.01604112
34MP0009785_altered_susceptibility_to2.01302675
35MP0003300_gastrointestinal_ulcer2.01139792
36MP0005025_abnormal_response_to2.00906064
37MP0001835_abnormal_antigen_presentation1.95123939
38MP0000689_abnormal_spleen_morphology1.90126844
39MP0006082_CNS_inflammation1.88216331
40MP0002933_joint_inflammation1.81525334
41MP0010155_abnormal_intestine_physiology1.74909615
42MP0010307_abnormal_tumor_latency1.74863707
43MP0001873_stomach_inflammation1.67279047
44MP0005310_abnormal_salivary_gland1.65907154
45MP0002429_abnormal_blood_cell1.63390507
46MP0005451_abnormal_body_composition1.63267299
47MP0000465_gastrointestinal_hemorrhage1.54783517
48MP0002796_impaired_skin_barrier1.47704574
49MP0004185_abnormal_adipocyte_glucose1.44826742
50MP0004510_myositis1.44579524
51MP0001191_abnormal_skin_condition1.44341428
52MP0003787_abnormal_imprinting1.44251156
53MP0010678_abnormal_skin_adnexa1.42712289
54MP0000015_abnormal_ear_pigmentation1.39237483
55MP0004808_abnormal_hematopoietic_stem1.37732034
56MP0001853_heart_inflammation1.35188702
57MP0001216_abnormal_epidermal_layer1.34790281
58MP0002419_abnormal_innate_immunity1.33400445
59MP0002148_abnormal_hypersensitivity_rea1.29389763
60MP0005464_abnormal_platelet_physiology1.25971458
61MP0002822_catalepsy1.25027035
62MP0003566_abnormal_cell_adhesion1.24676769
63MP0005023_abnormal_wound_healing1.23191037
64MP0001845_abnormal_inflammatory_respons1.21486997
65MP0002163_abnormal_gland_morphology1.20523047
66MP0000858_altered_metastatic_potential1.19566405
67MP0005501_abnormal_skin_physiology1.18651999
68MP0001348_abnormal_lacrimal_gland1.15805772
69MP0001243_abnormal_dermal_layer1.15373057
70MP0005075_abnormal_melanosome_morpholog1.15159479
71MP0000377_abnormal_hair_follicle1.14481620
72MP0006054_spinal_hemorrhage1.10216752
73MP0001533_abnormal_skeleton_physiology1.05625507
74MP0008961_abnormal_basal_metabolism1.03843555
75MP0002009_preneoplasia1.01807916
76MP0009764_decreased_sensitivity_to1.00610171
77MP0009765_abnormal_xenobiotic_induced0.97985506
78MP0002090_abnormal_vision0.94660697
79MP0003453_abnormal_keratinocyte_physiol0.92468684
80MP0002876_abnormal_thyroid_physiology0.91658940
81MP0000627_abnormal_mammary_gland0.91065449
82MP0005379_endocrine/exocrine_gland_phen0.90938346
83MP0003183_abnormal_peptide_metabolism0.90052381
84MP0008260_abnormal_autophagy0.89713099
85MP0000647_abnormal_sebaceous_gland0.88971015
86MP0005076_abnormal_cell_differentiation0.88548275
87MP0001851_eye_inflammation0.87875583
88MP0003806_abnormal_nucleotide_metabolis0.87027430
89MP0000490_abnormal_crypts_of0.86831832
90MP0005174_abnormal_tail_pigmentation0.86004994
91MP0002132_abnormal_respiratory_system0.82377077
92MP0003786_premature_aging0.77511456
93MP0002019_abnormal_tumor_incidence0.76181688
94MP0003448_altered_tumor_morphology0.75566553
95MP0003172_abnormal_lysosome_physiology0.75249952
96MP0003075_altered_response_to0.73255706
97MP0002138_abnormal_hepatobiliary_system0.71830550
98MP0003941_abnormal_skin_development0.71665780
99MP0001958_emphysema0.70266221
100MP0009384_cardiac_valve_regurgitation0.70084298
101MP0000367_abnormal_coat/_hair0.69319516
102MP0002998_abnormal_bone_remodeling0.67856738
103MP0003091_abnormal_cell_migration0.67664762
104MP0002693_abnormal_pancreas_physiology0.66816037
105MP0003221_abnormal_cardiomyocyte_apopto0.65023471
106MP0002095_abnormal_skin_pigmentation0.64736434
107MP0006035_abnormal_mitochondrial_morpho0.63186300
108MP0002060_abnormal_skin_morphology0.62078301
109MP0010771_integument_phenotype0.58024108
110MP0010352_gastrointestinal_tract_polyps0.57748050
111MP0009763_increased_sensitivity_to0.56750986
112MP0005390_skeleton_phenotype0.56731202
113MP0000372_irregular_coat_pigmentation0.56500144
114MP0002136_abnormal_kidney_physiology0.56323075
115MP0005166_decreased_susceptibility_to0.55616823
116MP0003795_abnormal_bone_structure0.54541975
117MP0002098_abnormal_vibrissa_morphology0.54333739
118MP0000477_abnormal_intestine_morphology0.54102060
119MP0005584_abnormal_enzyme/coenzyme_acti0.53889908
120MP0001340_abnormal_eyelid_morphology0.53714292
121MP0001881_abnormal_mammary_gland0.53597435
122MP0008469_abnormal_protein_level0.53575163
123MP0008569_lethality_at_weaning0.53103674
124MP0009931_abnormal_skin_appearance0.52844120
125MP0001188_hyperpigmentation0.51418239
126MP0001919_abnormal_reproductive_system0.50523772
127MP0000604_amyloidosis0.49598172
128MP0003045_fibrosis0.48894708
129MP0000920_abnormal_myelination0.47257461
130MP0008873_increased_physiological_sensi0.45129687
131MP0008877_abnormal_DNA_methylation0.44229818
132MP0003329_amyloid_beta_deposits0.43226430
133MP0000371_diluted_coat_color0.43183193
134MP0002168_other_aberrant_phenotype0.42898007
135MP0008874_decreased_physiological_sensi0.42296994
136MP0004742_abnormal_vestibular_system0.39864895
137MP0001663_abnormal_digestive_system0.39683717
138MP0002083_premature_death0.37154953
139MP0000249_abnormal_blood_vessel0.36616152

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)7.08920847
2Abnormality of T cell number (HP:0011839)6.75431981
3Severe combined immunodeficiency (HP:0004430)5.84024844
4Panhypogammaglobulinemia (HP:0003139)5.70132739
5Combined immunodeficiency (HP:0005387)5.54572823
6Stomatitis (HP:0010280)5.14670070
7Abnormality of T cells (HP:0002843)4.75777291
8Congenital stationary night blindness (HP:0007642)4.69875710
9Eczematoid dermatitis (HP:0000976)4.61219956
10Abnormality of the fingertips (HP:0001211)4.53201744
11Elevated erythrocyte sedimentation rate (HP:0003565)4.52528232
12Nasal polyposis (HP:0100582)4.33298405
13Recurrent bronchitis (HP:0002837)4.31646292
14Recurrent fungal infections (HP:0002841)4.28824335
15Autoimmune hemolytic anemia (HP:0001890)4.28662661
16IgM deficiency (HP:0002850)4.13556078
17Recurrent viral infections (HP:0004429)3.99492849
18Aplastic anemia (HP:0001915)3.93388366
19Pustule (HP:0200039)3.78659948
20Abnormality of oral frenula (HP:0000190)3.70198477
21Eosinophilia (HP:0001880)3.67726907
22Chronic otitis media (HP:0000389)3.62126898
23Obstructive lung disease (HP:0006536)3.56921067
24Chronic obstructive pulmonary disease (HP:0006510)3.56921067
25Abnormality of macrophages (HP:0004311)3.56239910
26Abnormality of the nasal mucosa (HP:0000433)3.53602382
27Hypoplasia of the thymus (HP:0000778)3.51940487
28Recurrent bacterial skin infections (HP:0005406)3.48184657
29Sex reversal (HP:0012245)3.48156793
30Abnormal sex determination (HP:0012244)3.48156793
31Abnormal delayed hypersensitivity skin test (HP:0002963)3.46905508
32Abnormality of eosinophils (HP:0001879)3.40286527
33Colitis (HP:0002583)3.37596453
34Mediastinal lymphadenopathy (HP:0100721)3.37036880
35Chronic diarrhea (HP:0002028)3.32713484
36Inflammation of the large intestine (HP:0002037)3.32030827
37IgG deficiency (HP:0004315)3.31494260
38Pulmonary infiltrates (HP:0002113)3.27237588
39Chronic mucocutaneous candidiasis (HP:0002728)3.25346340
40Recurrent cutaneous fungal infections (HP:0011370)3.25346340
41Gastrointestinal inflammation (HP:0004386)3.19634626
42Lymphopenia (HP:0001888)3.11737078
43Orchitis (HP:0100796)3.08447682
44Severe Myopia (HP:0011003)3.03340751
45IgA deficiency (HP:0002720)3.03302481
46Abnormality of cells of the lymphoid lineage (HP:0012140)3.01600085
47Granulocytopenia (HP:0001913)2.99142831
48Joint swelling (HP:0001386)2.98189442
49Optic neuritis (HP:0100653)2.96542453
50Retrobulbar optic neuritis (HP:0100654)2.96542453
51Encephalitis (HP:0002383)2.93729166
52Periodontitis (HP:0000704)2.92961765
53Leukocytosis (HP:0001974)2.91559769
54B lymphocytopenia (HP:0010976)2.91425735
55Abnormality of B cell number (HP:0010975)2.91425735
56Recurrent sinusitis (HP:0011108)2.91315739
57Increased IgE level (HP:0003212)2.87993596
58Hemoptysis (HP:0002105)2.85666416
59Abnormality of T cell physiology (HP:0011840)2.85176327
60Agammaglobulinemia (HP:0004432)2.79251549
61Abnormality of the gastric mucosa (HP:0004295)2.70022996
62Decreased activity of mitochondrial respiratory chain (HP:0008972)2.68726506
63Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.68726506
64Upper limb muscle weakness (HP:0003484)2.66250703
65Prostate neoplasm (HP:0100787)2.62762229
66Abnormality of male internal genitalia (HP:0000022)2.50371136
67Gangrene (HP:0100758)2.46458639
68Bronchitis (HP:0012387)2.44970627
69Hypoproteinemia (HP:0003075)2.43987870
70Abnormality of the prostate (HP:0008775)2.43761078
71Abnormality of the pleura (HP:0002103)2.42585074
72Acute hepatic failure (HP:0006554)2.41987721
73Increased density of long bones (HP:0006392)2.41579037
74Thyroiditis (HP:0100646)2.41547762
75Villous atrophy (HP:0011473)2.41488347
76Abnormality of small intestinal villus morphology (HP:0011472)2.41488347
77Increased IgM level (HP:0003496)2.41464213
78Episodic fever (HP:0001954)2.39050658
79Pulmonary embolism (HP:0002204)2.36644854
80Autoimmune thrombocytopenia (HP:0001973)2.34852169
81Arterial thrombosis (HP:0004420)2.30499934
82Anorexia (HP:0002039)2.28175735
83Recurrent otitis media (HP:0000403)2.24679850
84Hepatosplenomegaly (HP:0001433)2.24650064
85Pulmonary fibrosis (HP:0002206)2.23871950
86Emphysema (HP:0002097)2.22901178
87Metaphyseal dysplasia (HP:0100255)2.22843973
88Spondylolisthesis (HP:0003302)2.22789810
89Gingivitis (HP:0000230)2.22677636
90Chronic sinusitis (HP:0011109)2.20103487
91Premature loss of primary teeth (HP:0006323)2.19346541
92Verrucae (HP:0200043)2.19207446
93Papilloma (HP:0012740)2.19207446
94Polyneuropathy (HP:0001271)2.17760105
95Ureteral obstruction (HP:0006000)2.17125603
96Keratoconjunctivitis sicca (HP:0001097)2.15356676
97Abnormal platelet volume (HP:0011876)2.11830262
98Lymphoma (HP:0002665)2.11505068
99Basal cell carcinoma (HP:0002671)2.11499937
100Hypergammaglobulinemia (HP:0010702)2.09526899
101Aortic aneurysm (HP:0004942)2.05156997
102Distal lower limb amyotrophy (HP:0008944)2.03244462
103Diplopia (HP:0000651)2.01496023
104Abnormality of binocular vision (HP:0011514)2.01496023
105Anhidrosis (HP:0000970)2.00971857
106Meningitis (HP:0001287)2.00913431
107Hypercortisolism (HP:0001578)2.00275527
108Vasculitis (HP:0002633)1.99788709
109Erythema (HP:0010783)1.97871784
110Skin rash (HP:0000988)1.97482666
111Microretrognathia (HP:0000308)1.95993454
112Recurrent gram-negative bacterial infections (HP:0005420)1.95907441
113Progressive inability to walk (HP:0002505)1.95418780
114Keratoconjunctivitis (HP:0001096)1.95106318
115Gastrointestinal infarctions (HP:0005244)1.94795829
116Alveolar cell carcinoma (HP:0006519)1.94621899
117Recurrent skin infections (HP:0001581)1.94477225
118Amaurosis fugax (HP:0100576)1.93976428
119Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.93695527
120Hypochromic anemia (HP:0001931)1.92851940
121Testicular neoplasm (HP:0010788)1.91893930
122Recurrent abscess formation (HP:0002722)1.91414493
123Bifid scrotum (HP:0000048)1.89668242
124Glomerulopathy (HP:0100820)1.89620535
125Spontaneous hematomas (HP:0007420)1.87728203
126Thrombocytosis (HP:0001894)1.87063026
127Increased intramyocellular lipid droplets (HP:0012240)1.84686292
128Bronchiectasis (HP:0002110)1.84362771
129Zonular cataract (HP:0010920)1.84052270
130Epistaxis (HP:0000421)1.83385863
131Poor speech (HP:0002465)1.83255673
132Hepatitis (HP:0012115)1.82797540
133Urticaria (HP:0001025)1.82692027
134Protrusio acetabuli (HP:0003179)1.79903967
135Papilledema (HP:0001085)1.79492361
136Abnormality of nail color (HP:0100643)1.78735920
137Gingival bleeding (HP:0000225)1.76978190
138Increased mean platelet volume (HP:0011877)1.76477487
139Keratitis (HP:0000491)1.75514125
140Gastrointestinal stroma tumor (HP:0100723)1.74561545
141Aplasia/Hypoplasia of the thymus (HP:0010515)1.72465406
142Dilatation of the ascending aorta (HP:0005111)1.71435302
143Woolly hair (HP:0002224)1.70828077
144Prolonged bleeding time (HP:0003010)1.70434732
145Myositis (HP:0100614)1.68748614
146Stridor (HP:0010307)1.57014721
147Chest pain (HP:0100749)1.56918663
148Ureteral stenosis (HP:0000071)1.55887293
149Onion bulb formation (HP:0003383)1.53353048
150Bicuspid aortic valve (HP:0001647)1.53283657

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.11182337
2TXK4.89008504
3EEF2K4.18718579
4ZAP703.62465937
5PIK3CA3.08395865
6ITK2.85666681
7FGFR42.76320360
8JAK32.61522644
9ALK2.56719264
10STK102.53932322
11DMPK2.31622315
12GRK62.13363847
13NLK2.11521505
14RIPK42.07668199
15HCK1.97339249
16IKBKE1.94778100
17TYK21.89567880
18LCK1.86566396
19NME21.71882165
20MAP3K141.71693058
21MST41.67548862
22CSK1.65013048
23SYK1.60234729
24EIF2AK31.59301249
25PRKCH1.58947948
26FGFR31.55296621
27JAK11.54885626
28MAP3K101.43915511
29TEC1.42543502
30AKT31.31716213
31EIF2AK11.25501788
32MAP3K131.23744773
33TAOK11.23139491
34FES1.22915029
35GRK11.21353637
36KDR1.21136527
37SIK31.19079103
38TGFBR11.18369424
39PRKCQ1.16679087
40RPS6KB21.14787654
41MAP3K71.11494650
42PKN21.11373262
43MAP3K121.11053466
44EPHB21.10194900
45CAMKK21.09922653
46BRD41.03696338
47LRRK21.02295628
48IRAK41.01853508
49IKBKB0.96383540
50NUAK10.94882982
51TNK20.93606891
52TAOK30.93141566
53MAPKAPK30.92040278
54RPS6KA40.90517968
55PASK0.90286846
56MAP3K110.86679569
57MAP4K20.85548561
58TBK10.85024641
59PRKD30.83238025
60CAMKK10.82023183
61BTK0.80687618
62CHUK0.80629304
63TTN0.79225756
64MARK20.76240491
65EPHB10.76202936
66BCR0.76039000
67TRIB30.75552828
68CDK40.75273129
69CSF1R0.72368897
70EPHA30.71740170
71TESK20.71159546
72GRK70.70350748
73BMPR20.69636303
74TRPM70.69430171
75HIPK20.68914665
76JAK20.68306240
77FGR0.68078697
78LYN0.66743745
79TLK10.63286720
80PIM10.61711585
81CDK120.60816898
82VRK20.58999650
83CDK60.57360487
84PDGFRB0.57188380
85MATK0.57102032
86ROCK20.57044325
87INSR0.54569922
88PRPF4B0.51916080
89FYN0.51901035
90MAPK70.50645213
91BLK0.50633117
92MARK30.50527039
93TYRO30.49727186
94ADRBK20.49325913
95BCKDK0.48992879
96FGFR10.48885500
97KIT0.48370471
98PDK10.46427365
99PRKD20.46328873
100MAPK120.45661772
101DAPK10.44725282
102IGF1R0.42887214
103RET0.42544069
104RPS6KA10.42122338
105RPS6KA50.41961790
106PAK20.41347395
107CDK90.40886228
108MAP3K10.40170627
109PRKCD0.40003292
110PIM20.39702312
111MAPK110.39219322
112MAP3K80.38372054
113MAP2K60.38112648
114SGK20.37010765
115IRAK10.36361085
116MAPKAPK20.35703229
117SGK30.35345766
118MAPK40.35218828
119NTRK20.34337890
120ERN10.33877003
121SIK10.33797453
122PRKD10.33397916
123EGFR0.33219068
124PRKCB0.32415999
125RPS6KA20.32320391
126CLK10.32182750
127CSNK1D0.31911472
128STK110.30993764
129SIK20.30674920
130RPS6KA60.30321988
131FGFR20.29595008
132MAPK150.27991944
133TGFBR20.27035541
134TSSK60.26615672
135VRK10.25433786
136MAP3K50.24017506
137FRK0.23214076
138SMG10.20755808
139PAK10.20045654
140CDK80.17840793
141DAPK20.17786166

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.42917942
2T cell receptor signaling pathway_Homo sapiens_hsa046604.36056085
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.97330320
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.88570096
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.78183916
6Measles_Homo sapiens_hsa051622.66693772
7Proteasome_Homo sapiens_hsa030502.35640389
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.17914053
9Hematopoietic cell lineage_Homo sapiens_hsa046402.10844568
10Antigen processing and presentation_Homo sapiens_hsa046122.04025175
11B cell receptor signaling pathway_Homo sapiens_hsa046621.86517685
12Graft-versus-host disease_Homo sapiens_hsa053321.82204286
13Osteoclast differentiation_Homo sapiens_hsa043801.78563424
14Allograft rejection_Homo sapiens_hsa053301.77028800
15Leishmaniasis_Homo sapiens_hsa051401.75659868
16Cyanoamino acid metabolism_Homo sapiens_hsa004601.68542874
17Acute myeloid leukemia_Homo sapiens_hsa052211.64264955
18Viral myocarditis_Homo sapiens_hsa054161.63663998
19Herpes simplex infection_Homo sapiens_hsa051681.61706049
20HTLV-I infection_Homo sapiens_hsa051661.56726843
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.47956219
22Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.46555869
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.45570982
24Chemokine signaling pathway_Homo sapiens_hsa040621.44029310
25Viral carcinogenesis_Homo sapiens_hsa052031.39610014
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.35449589
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.30825724
28Ribosome_Homo sapiens_hsa030101.30722777
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27380420
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.22748892
31Autoimmune thyroid disease_Homo sapiens_hsa053201.19670132
32Hepatitis B_Homo sapiens_hsa051611.12643696
33Toxoplasmosis_Homo sapiens_hsa051451.11554940
34AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11383833
35Epstein-Barr virus infection_Homo sapiens_hsa051691.10905002
36Pancreatic cancer_Homo sapiens_hsa052121.08633413
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.07559120
38Chronic myeloid leukemia_Homo sapiens_hsa052201.05620995
39Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.04846567
40Non-small cell lung cancer_Homo sapiens_hsa052231.03972682
41Type I diabetes mellitus_Homo sapiens_hsa049401.02566149
42Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02426939
43Small cell lung cancer_Homo sapiens_hsa052221.02357338
44Lysine degradation_Homo sapiens_hsa003101.00021661
45Apoptosis_Homo sapiens_hsa042100.99511007
46Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.95681033
47Staphylococcus aureus infection_Homo sapiens_hsa051500.95175475
48Shigellosis_Homo sapiens_hsa051310.94837154
49TNF signaling pathway_Homo sapiens_hsa046680.93060723
50Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88018708
51Influenza A_Homo sapiens_hsa051640.87419562
52Platelet activation_Homo sapiens_hsa046110.86050494
53Colorectal cancer_Homo sapiens_hsa052100.81843322
54Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79069008
55Toll-like receptor signaling pathway_Homo sapiens_hsa046200.76618395
56Hepatitis C_Homo sapiens_hsa051600.76531119
57Legionellosis_Homo sapiens_hsa051340.76481953
58Salmonella infection_Homo sapiens_hsa051320.75979956
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74265917
60Prolactin signaling pathway_Homo sapiens_hsa049170.72286251
61VEGF signaling pathway_Homo sapiens_hsa043700.71808762
62Sulfur relay system_Homo sapiens_hsa041220.71580956
63Rap1 signaling pathway_Homo sapiens_hsa040150.68442110
64African trypanosomiasis_Homo sapiens_hsa051430.67191696
65Inositol phosphate metabolism_Homo sapiens_hsa005620.63736093
66MAPK signaling pathway_Homo sapiens_hsa040100.63710876
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.62971263
68Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.62950079
69Sphingolipid signaling pathway_Homo sapiens_hsa040710.61170173
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60890450
71Pertussis_Homo sapiens_hsa051330.60153247
72FoxO signaling pathway_Homo sapiens_hsa040680.60025408
73Oxidative phosphorylation_Homo sapiens_hsa001900.59024682
74Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58835881
75Endocytosis_Homo sapiens_hsa041440.58085432
76p53 signaling pathway_Homo sapiens_hsa041150.57869697
77MicroRNAs in cancer_Homo sapiens_hsa052060.55628647
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55628467
79Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55543797
80Prostate cancer_Homo sapiens_hsa052150.50571497
81Parkinsons disease_Homo sapiens_hsa050120.50113333
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50100200
83Tuberculosis_Homo sapiens_hsa051520.49984011
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49917223
85Thyroid cancer_Homo sapiens_hsa052160.49561781
86Malaria_Homo sapiens_hsa051440.49069005
87Protein export_Homo sapiens_hsa030600.46290965
88Regulation of autophagy_Homo sapiens_hsa041400.46033706
89Pathways in cancer_Homo sapiens_hsa052000.44687085
90Notch signaling pathway_Homo sapiens_hsa043300.44660853
91Endometrial cancer_Homo sapiens_hsa052130.42368838
92Phototransduction_Homo sapiens_hsa047440.40937386
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.40696657
94Rheumatoid arthritis_Homo sapiens_hsa053230.38135813
95Systemic lupus erythematosus_Homo sapiens_hsa053220.37580714
96Non-homologous end-joining_Homo sapiens_hsa034500.36858510
97Proteoglycans in cancer_Homo sapiens_hsa052050.35948813
98Spliceosome_Homo sapiens_hsa030400.35678465
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.34988071
100N-Glycan biosynthesis_Homo sapiens_hsa005100.33883769
101Phagosome_Homo sapiens_hsa041450.32558576
102Insulin resistance_Homo sapiens_hsa049310.32059472
103Galactose metabolism_Homo sapiens_hsa000520.31774852
104Asthma_Homo sapiens_hsa053100.30423574
105Collecting duct acid secretion_Homo sapiens_hsa049660.30313889
106ABC transporters_Homo sapiens_hsa020100.30191426
107Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.30113892
108Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.29844047
109Ras signaling pathway_Homo sapiens_hsa040140.29747807
110Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.29647176
111One carbon pool by folate_Homo sapiens_hsa006700.29249981
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28707907
113Adherens junction_Homo sapiens_hsa045200.28643603
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27152780
115Renal cell carcinoma_Homo sapiens_hsa052110.26177772
116Choline metabolism in cancer_Homo sapiens_hsa052310.22660150
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22003054
118Dorso-ventral axis formation_Homo sapiens_hsa043200.21417528
119alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.17625015
120Alzheimers disease_Homo sapiens_hsa050100.17545830
121Lysosome_Homo sapiens_hsa041420.16306057
122RNA degradation_Homo sapiens_hsa030180.15976543
123Basal transcription factors_Homo sapiens_hsa030220.14327505
124Peroxisome_Homo sapiens_hsa041460.11748639
125Circadian rhythm_Homo sapiens_hsa047100.09693089
126RNA polymerase_Homo sapiens_hsa030200.08714340
127Long-term potentiation_Homo sapiens_hsa047200.06090006
128Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.02868013
129Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.01009675
130Glycerophospholipid metabolism_Homo sapiens_hsa005640.00905488
131Nitrogen metabolism_Homo sapiens_hsa009100.00329715

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