TRAV16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)8.60076741
2negative thymic T cell selection (GO:0045060)7.93074660
3positive regulation of gamma-delta T cell activation (GO:0046645)7.75146120
4positive T cell selection (GO:0043368)7.33274941
5positive thymic T cell selection (GO:0045059)7.06712154
6regulation of gamma-delta T cell differentiation (GO:0045586)6.88178264
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.76108703
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.76108703
9thymic T cell selection (GO:0045061)6.75461730
10regulation of isotype switching to IgG isotypes (GO:0048302)6.63382383
11positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.59787272
12negative regulation of cell killing (GO:0031342)6.53992790
13negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.53992790
14T cell selection (GO:0045058)6.51884658
15interferon-gamma production (GO:0032609)6.29201213
16positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.22236747
17regulation of gamma-delta T cell activation (GO:0046643)6.20858201
18response to interleukin-15 (GO:0070672)5.60574475
19antigen processing and presentation of endogenous antigen (GO:0019883)5.53614142
20regulation of interleukin-12 biosynthetic process (GO:0045075)5.51930688
21activated T cell proliferation (GO:0050798)5.49157254
22T cell receptor signaling pathway (GO:0050852)5.48384926
23regulation of T cell tolerance induction (GO:0002664)5.44424801
24cytidine deamination (GO:0009972)5.37976763
25cytidine metabolic process (GO:0046087)5.37976763
26cytidine catabolic process (GO:0006216)5.37976763
27pyrimidine ribonucleoside catabolic process (GO:0046133)5.33329017
28T cell migration (GO:0072678)5.20005558
29cellular response to interleukin-15 (GO:0071350)5.16998940
30T cell costimulation (GO:0031295)4.95115234
31leukocyte aggregation (GO:0070486)4.92164795
32lymphocyte costimulation (GO:0031294)4.85558424
33regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.78134054
34regulation of alpha-beta T cell proliferation (GO:0046640)4.74911269
35regulation of interleukin-2 biosynthetic process (GO:0045076)4.68997967
36positive regulation of natural killer cell mediated immunity (GO:0002717)4.68511816
37positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.68511816
38regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.64305375
39positive regulation of uterine smooth muscle contraction (GO:0070474)4.62797139
40positive regulation of isotype switching (GO:0045830)4.62149864
41positive regulation of alpha-beta T cell proliferation (GO:0046641)4.51854200
42regulation of natural killer cell mediated immunity (GO:0002715)4.49613316
43regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.49613316
44antigen receptor-mediated signaling pathway (GO:0050851)4.44981752
45positive regulation of interleukin-2 production (GO:0032743)4.41402143
46positive regulation of tolerance induction (GO:0002645)4.39528753
47lymphocyte chemotaxis (GO:0048247)4.39273884
48regulation of T cell receptor signaling pathway (GO:0050856)4.19925771
49negative regulation of T cell mediated immunity (GO:0002710)4.18802728
50positive regulation of immunoglobulin mediated immune response (GO:0002891)4.18555331
51positive regulation of B cell mediated immunity (GO:0002714)4.18555331
52positive regulation of immune response to tumor cell (GO:0002839)4.17609874
53regulation of immune response to tumor cell (GO:0002837)4.17609874
54regulation of response to tumor cell (GO:0002834)4.17609874
55positive regulation of response to tumor cell (GO:0002836)4.17609874
56DNA deamination (GO:0045006)4.15938426
57regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.10809897
58regulation of B cell receptor signaling pathway (GO:0050855)4.05832942
59dendritic cell chemotaxis (GO:0002407)4.02150886
60positive regulation of humoral immune response (GO:0002922)4.01374572
61chemokine-mediated signaling pathway (GO:0070098)3.99245310
62positive regulation of DNA recombination (GO:0045911)3.93131614
63regulation of chronic inflammatory response (GO:0002676)3.90852574
64regulation of isotype switching (GO:0045191)3.89443584
65alpha-beta T cell differentiation (GO:0046632)3.87531693
66regulation of tolerance induction (GO:0002643)3.87425935
67positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.86175514
68mast cell activation (GO:0045576)3.85108508
69alpha-beta T cell activation (GO:0046631)3.84135415
70antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.81863191
71regulation of regulatory T cell differentiation (GO:0045589)3.79725375
72B cell receptor signaling pathway (GO:0050853)3.78346238
73T cell differentiation (GO:0030217)3.78051771
74positive regulation of cell killing (GO:0031343)3.71092947
75regulation of immunoglobulin mediated immune response (GO:0002889)3.68133500
76regulation of activation of Janus kinase activity (GO:0010533)3.67491120
77positive regulation of calcium-mediated signaling (GO:0050850)3.62428184
78regulation of leukocyte mediated cytotoxicity (GO:0001910)3.62239621
79regulation of B cell mediated immunity (GO:0002712)3.54907923
80negative regulation of execution phase of apoptosis (GO:1900118)3.54801368
81positive regulation of defense response to virus by host (GO:0002230)3.53717854
82regulation of response to interferon-gamma (GO:0060330)3.51207364
83V(D)J recombination (GO:0033151)3.49729483
84regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.47603192
85regulation of cell killing (GO:0031341)3.46927912
86negative regulation of T cell apoptotic process (GO:0070233)3.45217844
87tolerance induction (GO:0002507)3.44493909
88regulation of uterine smooth muscle contraction (GO:0070472)3.43886443
89negative regulation of B cell proliferation (GO:0030889)3.42960557
90T cell activation (GO:0042110)3.40281613
91positive regulation of immunoglobulin production (GO:0002639)3.38735170
92regulation of interleukin-2 production (GO:0032663)3.37245429
93positive regulation of T cell chemotaxis (GO:0010820)3.35943634
94regulation of T cell chemotaxis (GO:0010819)3.35943634
95gonadal mesoderm development (GO:0007506)3.35374993
96negative regulation of B cell activation (GO:0050869)3.35253539
97dendritic cell migration (GO:0036336)3.33105316
98negative regulation of lymphocyte mediated immunity (GO:0002707)3.32995960
99T cell homeostasis (GO:0043029)3.30018346
100positive regulation of granulocyte differentiation (GO:0030854)3.29582085
101positive regulation of T cell differentiation in thymus (GO:0033089)3.29317850
102negative regulation of T cell receptor signaling pathway (GO:0050860)3.29297585
103lymph node development (GO:0048535)3.27714843
104CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.24412282
105regulation of immunoglobulin production (GO:0002637)3.23253109
106regulation of defense response to virus by virus (GO:0050690)3.22986828
107positive regulation of lymphocyte mediated immunity (GO:0002708)3.19878597
108T cell proliferation (GO:0042098)3.19701962
109positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.18514957
110cellular response to interleukin-4 (GO:0071353)3.17262867
111lymphocyte migration (GO:0072676)3.15499500
112leukocyte cell-cell adhesion (GO:0007159)3.13675385
113regulation of interleukin-4 production (GO:0032673)3.13160395
114positive regulation of T cell mediated cytotoxicity (GO:0001916)3.13113373
115regulation of B cell differentiation (GO:0045577)3.12857696
116positive regulation of T cell activation (GO:0050870)3.12131319
117cellular defense response (GO:0006968)3.10171273
118positive regulation of interleukin-4 production (GO:0032753)3.09680352
119Arp2/3 complex-mediated actin nucleation (GO:0034314)3.08542417
120positive regulation of alpha-beta T cell activation (GO:0046635)3.08140698
121NIK/NF-kappaB signaling (GO:0038061)3.07171084
122negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.07107306
123immune response-activating cell surface receptor signaling pathway (GO:0002429)3.06450931
124regulation of T cell mediated cytotoxicity (GO:0001914)3.05516435
125viral transcription (GO:0019083)3.04210314
126antigen processing and presentation via MHC class Ib (GO:0002475)3.03957316
127regulation of type I interferon-mediated signaling pathway (GO:0060338)3.01927886
128signal complex assembly (GO:0007172)3.01083270
129regulation of lymphocyte mediated immunity (GO:0002706)3.00582457
130positive regulation of interleukin-8 secretion (GO:2000484)2.99637467
131Peyers patch development (GO:0048541)2.98652868
132mucosal-associated lymphoid tissue development (GO:0048537)2.98652868
133regulation of alpha-beta T cell activation (GO:0046634)2.98253996

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.31625132
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.51335121
3MYC_22102868_ChIP-Seq_BL_Human3.97452216
4STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.84567185
5E2F7_22180533_ChIP-Seq_HELA_Human3.83484049
6FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.70793722
7RUNX_20019798_ChIP-Seq_JUKART_Human3.67631878
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.50607729
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.45672927
10STAT4_19710469_ChIP-ChIP_TH1__Mouse3.37465849
11MYB_26560356_Chip-Seq_TH2_Human3.32133197
12IRF8_22096565_ChIP-ChIP_GC-B_Human3.29073996
13MAF_26560356_Chip-Seq_TH1_Human2.97583423
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.89672131
15UTX_26944678_Chip-Seq_JUKART_Human2.80861165
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.77476425
17MYB_26560356_Chip-Seq_TH1_Human2.72340145
18NOTCH1_21737748_ChIP-Seq_TLL_Human2.54836682
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.44122554
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.42662098
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.39575385
22VDR_21846776_ChIP-Seq_THP-1_Human2.30279457
23KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.22901649
24MAF_26560356_Chip-Seq_TH2_Human2.21901933
25BP1_19119308_ChIP-ChIP_Hs578T_Human2.19732556
26GATA3_27048872_Chip-Seq_THYMUS_Human2.17246900
27RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.12149499
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.07954375
29TCF7_22412390_ChIP-Seq_EML_Mouse2.00108638
30RUNX1_22412390_ChIP-Seq_EML_Mouse1.89556020
31KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.86264488
32MYB_21317192_ChIP-Seq_ERMYB_Mouse1.77866367
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.77406515
34KDM2B_26808549_Chip-Seq_DND41_Human1.77172153
35SPI1_23547873_ChIP-Seq_NB4_Human1.72288183
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.71283679
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.70686714
38IRF8_21731497_ChIP-ChIP_J774_Mouse1.70622788
39VDR_24763502_ChIP-Seq_THP-1_Human1.68621596
40NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.66079947
41SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.64668971
42EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.61194317
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.58926853
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.56955985
45CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.54453517
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.49940868
47LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.49094920
48RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.46913049
49CIITA_25753668_ChIP-Seq_RAJI_Human1.46843602
50IRF8_27001747_Chip-Seq_BMDM_Mouse1.45472568
51VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.44011105
52BRD4_27068464_Chip-Seq_AML-cells_Mouse1.43777887
53SCL_19346495_ChIP-Seq_HPC-7_Human1.40649211
54KDM2B_26808549_Chip-Seq_SUP-B15_Human1.39568576
55FOXM1_23109430_ChIP-Seq_U2OS_Human1.34487309
56MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.31491810
57RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.28610996
58VDR_23849224_ChIP-Seq_CD4+_Human1.28237677
59SPI1_23127762_ChIP-Seq_K562_Human1.27531767
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23751315
61GATA3_26560356_Chip-Seq_TH2_Human1.22630995
62KDM2B_26808549_Chip-Seq_JURKAT_Human1.22186820
63FOXP3_21729870_ChIP-Seq_TREG_Human1.19836459
64E2F4_17652178_ChIP-ChIP_JURKAT_Human1.19568180
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.11954895
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.07154826
67PU_27001747_Chip-Seq_BMDM_Mouse1.05891327
68GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04901104
69ELK1_19687146_ChIP-ChIP_HELA_Human1.02239327
70TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.00719011
71SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99240374
72CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97995069
73ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95828184
74DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94520551
75TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94108818
76VDR_24787735_ChIP-Seq_THP-1_Human0.93841818
77MYC_18555785_ChIP-Seq_MESCs_Mouse0.93473120
78GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.92193886
79MYC_19079543_ChIP-ChIP_MESCs_Mouse0.92101985
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.91354969
81NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.90948827
82FLI1_27457419_Chip-Seq_LIVER_Mouse0.89733337
83BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.89561333
84PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88623249
85RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88205717
86XRN2_22483619_ChIP-Seq_HELA_Human0.88131542
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.87769795
88TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85829536
89HOXB4_20404135_ChIP-ChIP_EML_Mouse0.85762232
90CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85743475
91PU.1_20513432_ChIP-Seq_Bcells_Mouse0.85536917
92CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.85490005
93FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85206842
94ELF1_20517297_ChIP-Seq_JURKAT_Human0.84935211
95BCL6_27268052_Chip-Seq_Bcells_Human0.82986207
96GATA3_26560356_Chip-Seq_TH1_Human0.82402837
97SMAD_19615063_ChIP-ChIP_OVARY_Human0.82144414
98NCOR1_26117541_ChIP-Seq_K562_Human0.81705944
99TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.81329831
100SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.80955390
101GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80591715
102CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79144897
103LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.78596459
104PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.77974368
105VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.77703890
106GABP_17652178_ChIP-ChIP_JURKAT_Human0.74489531
107KDM5A_27292631_Chip-Seq_BREAST_Human0.73678425
108SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.73304463
109PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.71469816
110PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.70202330
111SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.69807369
112PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.69091022
113STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.68391680
114SMRT_27268052_Chip-Seq_Bcells_Human0.67518993
115GATA1_22025678_ChIP-Seq_K562_Human0.67485052
116GATA1_19941827_ChIP-Seq_MEL_Mouse0.67213987
117EST1_17652178_ChIP-ChIP_JURKAT_Human0.66927557
118CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.66719796
119GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.65861278
120PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.65737766
121GATA1_19941826_ChIP-Seq_K562_Human0.65252223
122NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.64897058
123CEBPB_22108803_ChIP-Seq_LS180_Human0.64333818
124RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.63966820
125FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.63797425

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.28375895
2MP0005671_abnormal_response_to4.53612714
3MP0000685_abnormal_immune_system3.88505595
4MP0009333_abnormal_splenocyte_physiolog3.28941089
5MP0001835_abnormal_antigen_presentation3.11342217
6MP0000703_abnormal_thymus_morphology3.09785994
7MP0001800_abnormal_humoral_immune3.08801096
8MP0002398_abnormal_bone_marrow3.01274785
9MP0002166_altered_tumor_susceptibility3.00565597
10MP0002405_respiratory_system_inflammati2.88257513
11MP0002420_abnormal_adaptive_immunity2.85067495
12MP0005000_abnormal_immune_tolerance2.80367021
13MP0001819_abnormal_immune_cell2.79283614
14MP0005451_abnormal_body_composition2.78899616
15MP0002723_abnormal_immune_serum2.77925632
16MP0005387_immune_system_phenotype2.72590356
17MP0001790_abnormal_immune_system2.72590356
18MP0002396_abnormal_hematopoietic_system2.64796321
19MP0003436_decreased_susceptibility_to2.56968508
20MP0009785_altered_susceptibility_to2.56862140
21MP0001873_stomach_inflammation2.55758912
22MP0002006_tumorigenesis2.54994245
23MP0000716_abnormal_immune_system2.54545986
24MP0002722_abnormal_immune_system2.48130085
25MP0003866_abnormal_defecation2.47201134
26MP0003300_gastrointestinal_ulcer2.46076501
27MP0002452_abnormal_antigen_presenting2.46068764
28MP0000689_abnormal_spleen_morphology2.34601160
29MP0005025_abnormal_response_to2.32571428
30MP0006082_CNS_inflammation2.25926662
31MP0010155_abnormal_intestine_physiology2.22468952
32MP0002277_abnormal_respiratory_mucosa2.14351104
33MP0002429_abnormal_blood_cell2.09158631
34MP0004947_skin_inflammation2.04687596
35MP0003724_increased_susceptibility_to1.91557871
36MP0004381_abnormal_hair_follicle1.85835558
37MP0003303_peritoneal_inflammation1.85665820
38MP0004808_abnormal_hematopoietic_stem1.81573493
39MP0002933_joint_inflammation1.80436010
40MP0002148_abnormal_hypersensitivity_rea1.76000408
41MP0002163_abnormal_gland_morphology1.71081611
42MP0004510_myositis1.66674374
43MP0001845_abnormal_inflammatory_respons1.66495320
44MP0002419_abnormal_innate_immunity1.63300108
45MP0005464_abnormal_platelet_physiology1.61733924
46MP0003806_abnormal_nucleotide_metabolis1.50047265
47MP0001853_heart_inflammation1.44936849
48MP0000858_altered_metastatic_potential1.42821102
49MP0003448_altered_tumor_morphology1.28253772
50MP0002132_abnormal_respiratory_system1.22607562
51MP0005075_abnormal_melanosome_morpholog1.17875164
52MP0002019_abnormal_tumor_incidence1.15711680
53MP0009764_decreased_sensitivity_to1.11973360
54MP0008961_abnormal_basal_metabolism1.11592607
55MP0003786_premature_aging1.10494881
56MP0005310_abnormal_salivary_gland1.09279832
57MP0000465_gastrointestinal_hemorrhage1.06363562
58MP0008469_abnormal_protein_level1.01315027
59MP0010352_gastrointestinal_tract_polyps0.98348383
60MP0008057_abnormal_DNA_replication0.98289586
61MP0005397_hematopoietic_system_phenotyp0.97450210
62MP0001545_abnormal_hematopoietic_system0.97450210
63MP0000490_abnormal_crypts_of0.95412918
64MP0001533_abnormal_skeleton_physiology0.95359558
65MP0001851_eye_inflammation0.93443145
66MP0009765_abnormal_xenobiotic_induced0.86804131
67MP0004957_abnormal_blastocyst_morpholog0.85585775
68MP0002876_abnormal_thyroid_physiology0.84333198
69MP0002998_abnormal_bone_remodeling0.84302098
70MP0005023_abnormal_wound_healing0.80117316
71MP0001542_abnormal_bone_strength0.79449827
72MP0005379_endocrine/exocrine_gland_phen0.79243011
73MP0003329_amyloid_beta_deposits0.77556868
74MP0001919_abnormal_reproductive_system0.77260950
75MP0003077_abnormal_cell_cycle0.77147422
76MP0000372_irregular_coat_pigmentation0.76308381
77MP0002009_preneoplasia0.74757489
78MP0002254_reproductive_system_inflammat0.72004407
79MP0001346_abnormal_lacrimal_gland0.70905277
80MP0002138_abnormal_hepatobiliary_system0.69775875
81MP0005076_abnormal_cell_differentiation0.67114825
82MP0001243_abnormal_dermal_layer0.66847071
83MP0003252_abnormal_bile_duct0.66145086
84MP0002168_other_aberrant_phenotype0.65151080
85MP0010307_abnormal_tumor_latency0.64791161
86MP0004883_abnormal_blood_vessel0.62771282
87MP0000920_abnormal_myelination0.62735583
88MP0000609_abnormal_liver_physiology0.62669406
89MP0009278_abnormal_bone_marrow0.62405244
90MP0005390_skeleton_phenotype0.62369622
91MP0009763_increased_sensitivity_to0.61946976
92MP0003693_abnormal_embryo_hatching0.61008024
93MP0003646_muscle_fatigue0.60856913
94MP0003795_abnormal_bone_structure0.60288641
95MP0010094_abnormal_chromosome_stability0.59570479
96MP0000343_altered_response_to0.59135455
97MP0003045_fibrosis0.58859604
98MP0000249_abnormal_blood_vessel0.55749974
99MP0000477_abnormal_intestine_morphology0.54458225
100MP0001663_abnormal_digestive_system0.54183765
101MP0005174_abnormal_tail_pigmentation0.52050582
102MP0005381_digestive/alimentary_phenotyp0.51563110
103MP0009840_abnormal_foam_cell0.50673715
104MP0004185_abnormal_adipocyte_glucose0.50637153
105MP0003453_abnormal_keratinocyte_physiol0.50364294
106MP0000604_amyloidosis0.50097462
107MP0000350_abnormal_cell_proliferation0.49648704
108MP0008873_increased_physiological_sensi0.49238966
109MP0008007_abnormal_cellular_replicative0.48514033
110MP0001765_abnormal_ion_homeostasis0.47356131
111MP0000313_abnormal_cell_death0.47066693
112MP0003075_altered_response_to0.47065535
113MP0003183_abnormal_peptide_metabolism0.46805897
114MP0001216_abnormal_epidermal_layer0.45662893
115MP0003690_abnormal_glial_cell0.45252660
116MP0001730_embryonic_growth_arrest0.45208745
117MP0002136_abnormal_kidney_physiology0.44641253
118MP0005164_abnormal_response_to0.44486933
119MP0008569_lethality_at_weaning0.43280771
120MP0003091_abnormal_cell_migration0.41884561
121MP0002822_catalepsy0.41549109
122MP0002693_abnormal_pancreas_physiology0.40248715
123MP0008995_early_reproductive_senescence0.39754807
124MP0000367_abnormal_coat/_hair0.39582939
125MP0002083_premature_death0.39555326
126MP0005166_decreased_susceptibility_to0.39260951
127MP0001191_abnormal_skin_condition0.38733322
128MP0003959_abnormal_lean_body0.37420272
129MP0001348_abnormal_lacrimal_gland0.37280616
130MP0008770_decreased_survivor_rate0.37274010
131MP0009643_abnormal_urine_homeostasis0.34800172
132MP0004130_abnormal_muscle_cell0.33696844
133MP0003172_abnormal_lysosome_physiology0.33447691

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)9.00450391
2Abnormality of T cell number (HP:0011839)8.60195803
3Elevated erythrocyte sedimentation rate (HP:0003565)5.91416232
4Severe combined immunodeficiency (HP:0004430)5.90119978
5Abnormality of T cells (HP:0002843)5.89145627
6Combined immunodeficiency (HP:0005387)5.72858016
7Stomatitis (HP:0010280)5.65146238
8Nasal polyposis (HP:0100582)5.19312774
9Panhypogammaglobulinemia (HP:0003139)5.11038721
10Recurrent viral infections (HP:0004429)4.94339914
11Recurrent fungal infections (HP:0002841)4.77905280
12Chronic otitis media (HP:0000389)4.67199745
13Recurrent bronchitis (HP:0002837)4.59207673
14IgG deficiency (HP:0004315)4.41850061
15Abnormality of the nasal mucosa (HP:0000433)4.28301297
16Eosinophilia (HP:0001880)4.16460112
17Eczematoid dermatitis (HP:0000976)4.00893572
18Abnormal delayed hypersensitivity skin test (HP:0002963)3.97768082
19Abnormality of eosinophils (HP:0001879)3.96674835
20Pustule (HP:0200039)3.89605296
21IgM deficiency (HP:0002850)3.86945150
22Abnormality of B cell number (HP:0010975)3.86541794
23B lymphocytopenia (HP:0010976)3.86541794
24Abnormality of the fingertips (HP:0001211)3.84545334
25Recurrent cutaneous fungal infections (HP:0011370)3.59203818
26Chronic mucocutaneous candidiasis (HP:0002728)3.59203818
27Granulocytopenia (HP:0001913)3.59060206
28Chronic diarrhea (HP:0002028)3.51753425
29Leukocytosis (HP:0001974)3.48468404
30Abnormality of the prostate (HP:0008775)3.40197825
31Joint swelling (HP:0001386)3.40176509
32Thyroiditis (HP:0100646)3.39414114
33Myositis (HP:0100614)3.36856846
34Lymphopenia (HP:0001888)3.33233025
35Abnormality of T cell physiology (HP:0011840)3.28724471
36Increased IgM level (HP:0003496)3.24091481
37Abnormality of cells of the lymphoid lineage (HP:0012140)3.22416408
38Abnormality of macrophages (HP:0004311)3.15917038
39Autoimmune hemolytic anemia (HP:0001890)3.13154733
40Thrombocytosis (HP:0001894)3.12522972
41Spontaneous hematomas (HP:0007420)3.07294355
42Hypoplasia of the thymus (HP:0000778)3.05263585
43Autoimmune thrombocytopenia (HP:0001973)2.96916770
44Gastrointestinal infarctions (HP:0005244)2.96584182
45Orchitis (HP:0100796)2.89470164
46Basal cell carcinoma (HP:0002671)2.82713095
47Lymphoma (HP:0002665)2.73468847
48Gangrene (HP:0100758)2.70974204
49Bronchitis (HP:0012387)2.70642096
50IgA deficiency (HP:0002720)2.68903213
51Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.54498953
52Meningitis (HP:0001287)2.52743217
53Increased density of long bones (HP:0006392)2.48628915
54Inflammation of the large intestine (HP:0002037)2.46020616
55Mediastinal lymphadenopathy (HP:0100721)2.44893284
56Abnormality of the pleura (HP:0002103)2.43876060
57Chronic sinusitis (HP:0011109)2.43552584
58Hypergammaglobulinemia (HP:0010702)2.41793050
59Gastrointestinal inflammation (HP:0004386)2.41623810
60Hemoptysis (HP:0002105)2.40685262
61Increased IgE level (HP:0003212)2.39769614
62Encephalitis (HP:0002383)2.39554022
63Abnormal platelet volume (HP:0011876)2.38481772
64Agammaglobulinemia (HP:0004432)2.37484737
65Hypochromic anemia (HP:0001931)2.36781840
66Papilloma (HP:0012740)2.36215605
67Verrucae (HP:0200043)2.36215605
68Increased CSF protein (HP:0002922)2.33510522
69Vasculitis (HP:0002633)2.32538796
70Microvesicular hepatic steatosis (HP:0001414)2.26618145
71Keratoconjunctivitis (HP:0001096)2.26419678
72Renal cortical cysts (HP:0000803)2.25941854
73Recurrent sinusitis (HP:0011108)2.24158286
74Acute hepatic failure (HP:0006554)2.23039716
75Urticaria (HP:0001025)2.22940119
76Keratoconjunctivitis sicca (HP:0001097)2.22082083
77Sensory axonal neuropathy (HP:0003390)2.21855553
78Recurrent otitis media (HP:0000403)2.20683677
79Malnutrition (HP:0004395)2.19844704
80Recurrent skin infections (HP:0001581)2.18594907
81Recurrent abscess formation (HP:0002722)2.17529633
82Chest pain (HP:0100749)2.15715568
83Obstructive lung disease (HP:0006536)2.13744793
84Chronic obstructive pulmonary disease (HP:0006510)2.13744793
85Epistaxis (HP:0000421)2.12549407
86Micronodular cirrhosis (HP:0001413)2.07297137
87Bronchiectasis (HP:0002110)2.07017736
88Amaurosis fugax (HP:0100576)2.06322747
89Stomach cancer (HP:0012126)2.04963980
90Prolonged bleeding time (HP:0003010)2.03133464
91Testicular atrophy (HP:0000029)2.03034096
92Skin rash (HP:0000988)2.02948333
93Pulmonary infiltrates (HP:0002113)2.02841284
94Aplasia/Hypoplasia of the thymus (HP:0010515)2.02135729
95Arterial thrombosis (HP:0004420)1.99715161
96Bicuspid aortic valve (HP:0001647)1.99428459
97Abnormality of the pericardium (HP:0001697)1.96814249
98Poikiloderma (HP:0001029)1.96697711
99Persistence of primary teeth (HP:0006335)1.96660449
100Dysphonia (HP:0001618)1.96584663
101Pulmonary fibrosis (HP:0002206)1.95741700
102Abnormality of oral frenula (HP:0000190)1.95693145
103Alveolar cell carcinoma (HP:0006519)1.94653578
104Cheilitis (HP:0100825)1.94324367
105Increased mean platelet volume (HP:0011877)1.92719026
106Polyneuropathy (HP:0001271)1.92701591
107Glomerulopathy (HP:0100820)1.92134224
108Ureteral stenosis (HP:0000071)1.88676175
109Bile duct proliferation (HP:0001408)1.87704501
110Abnormal biliary tract physiology (HP:0012439)1.87704501
111Abnormality of male internal genitalia (HP:0000022)1.86507050
112Abnormality of cells of the erythroid lineage (HP:0012130)1.85880615
1133-Methylglutaconic aciduria (HP:0003535)1.85469027
114Dyschromatopsia (HP:0007641)1.85380542
115Retrobulbar optic neuritis (HP:0100654)1.85118936
116Optic neuritis (HP:0100653)1.85118936
117Pulmonary embolism (HP:0002204)1.84966642
118Hypoproteinemia (HP:0003075)1.84305922
119Hepatosplenomegaly (HP:0001433)1.83469551
120Anorexia (HP:0002039)1.83391588
121Hepatitis (HP:0012115)1.82654098
122Pancytopenia (HP:0001876)1.81970398
123Recurrent gram-negative bacterial infections (HP:0005420)1.81733025
124Gingival bleeding (HP:0000225)1.80817579
125Frequent falls (HP:0002359)1.80196174
126Acute myeloid leukemia (HP:0004808)1.78765013
127Neoplasm of the tracheobronchial system (HP:0100552)1.76025328
128Dislocated radial head (HP:0003083)1.75463722
129Entropion (HP:0000621)1.74652401
130Periodontitis (HP:0000704)1.73946016
131Trigonocephaly (HP:0000243)1.70106024
132Ureteral obstruction (HP:0006000)1.68896699
133Cellular immunodeficiency (HP:0005374)1.67146772
134Abnormal number of erythroid precursors (HP:0012131)1.65399636
135Recurrent bacterial skin infections (HP:0005406)1.64558183
136Broad palm (HP:0001169)1.62887503
137Abnormality of the radial head (HP:0003995)1.62692162

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.21251221
2MAP4K16.14517329
3ITK3.52399877
4ZAP703.46431633
5JAK33.27760517
6STK102.71688598
7FGFR42.61114749
8NLK2.58437427
9IKBKE2.18094997
10GRK62.16600125
11TYK22.08206004
12EEF2K2.06439577
13LCK1.92024354
14TEC1.91612123
15FGFR31.90348175
16CAMKK21.86313177
17MAPK111.85474626
18SCYL21.79695006
19CSK1.73784813
20PRPF4B1.68897497
21PKN21.68200010
22MST41.67767735
23CAMKK11.60001048
24MAP3K141.57625063
25RIPK41.52260454
26MAP3K101.50978100
27NME21.49060740
28SYK1.41598867
29PRKCH1.38785026
30JAK11.37144034
31LRRK21.35222952
32BTK1.34812294
33HCK1.34663215
34KIT1.34656809
35GRK71.23696197
36PRKCQ1.23510526
37FLT31.23454212
38TBK11.20147208
39MAP3K131.16881193
40MAP3K71.11173289
41IKBKB1.05895082
42RPS6KA41.04410689
43TRIB31.03051673
44TAOK31.01918305
45CDK121.01661183
46FES0.99865856
47ERN10.95244840
48TAOK10.93899953
49PIM10.92131859
50BCR0.91548941
51TYRO30.89432173
52MARK30.89320823
53PASK0.86775913
54ADRBK20.86773051
55BLK0.86489250
56EIF2AK10.84426305
57CLK10.84021067
58CHUK0.83230505
59PDGFRB0.81784984
60TAOK20.81648512
61IRAK40.81336094
62JAK20.79254923
63EPHB10.77951351
64PIK3CG0.75784753
65KDR0.74938090
66MELK0.73052449
67LYN0.72745020
68MARK20.69391183
69CSF1R0.69284880
70ALK0.66577411
71NME10.65488697
72SIK20.64262429
73FGFR10.60761637
74TESK20.58354498
75PDK10.57874477
76MAP2K30.57584711
77TLK10.57328180
78TGFBR10.56588002
79TNK20.55693804
80CDK40.55402580
81MAPK120.54954969
82RIPK10.52526677
83PIK3CA0.50261311
84RAF10.50173588
85RPS6KB20.50129089
86TTN0.48465866
87MAP3K80.45717940
88MAPK70.45698426
89PIM20.45334922
90STK40.43593910
91CDC70.43519033
92NUAK10.43262659
93INSR0.42771835
94TGFBR20.42736360
95HIPK20.42355896
96EPHA30.42326244
97FGFR20.42240610
98TSSK60.41192297
99PTK60.40991517
100STK110.40909265
101TESK10.39953398
102FYN0.37336567
103RPS6KA50.36899248
104MAPKAPK30.36785385
105MAPKAPK20.36744056
106MAP3K110.35114632
107STK240.35063999
108BMPR20.34801593
109TRPM70.34092100
110WNK40.32749994
111PDPK10.32393242
112MAP2K60.30643525
113ROCK20.30516466
114ACVR1B0.30115729
115PRKD20.30040634
116CDK90.29934937
117NTRK20.26588091
118ZAK0.26194914
119RPS6KA60.26008080
120IGF1R0.25929040
121EGFR0.25927378
122BRD40.25920335
123DMPK0.25147349
124MAPK40.24809022
125MAP3K30.24627280
126CDK60.23767374
127RPS6KA10.23253282
128EIF2AK30.21821118
129MAPK30.21655050
130SIK30.20347322
131CHEK10.20163381
132VRK10.16191058
133MAP2K20.15792794
134FGR0.15780758
135PRKCB0.13560842
136PRKCD0.13504188
137YES10.11653341
138MAPK90.11592311

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.48536274
2T cell receptor signaling pathway_Homo sapiens_hsa046604.32187470
3Graft-versus-host disease_Homo sapiens_hsa053323.52686666
4Allograft rejection_Homo sapiens_hsa053303.14595373
5Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.04458069
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.93109195
7Measles_Homo sapiens_hsa051622.80095346
8Antigen processing and presentation_Homo sapiens_hsa046122.59156787
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.55511444
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.32287598
11Type I diabetes mellitus_Homo sapiens_hsa049402.09091748
12Hematopoietic cell lineage_Homo sapiens_hsa046402.06633859
13Leishmaniasis_Homo sapiens_hsa051401.96787635
14Viral myocarditis_Homo sapiens_hsa054161.80163494
15Osteoclast differentiation_Homo sapiens_hsa043801.79442114
16Ribosome_Homo sapiens_hsa030101.76287875
17Jak-STAT signaling pathway_Homo sapiens_hsa046301.69796506
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.63016755
19Acute myeloid leukemia_Homo sapiens_hsa052211.60451824
20Herpes simplex infection_Homo sapiens_hsa051681.59444887
21Autoimmune thyroid disease_Homo sapiens_hsa053201.53680311
22B cell receptor signaling pathway_Homo sapiens_hsa046621.46191717
23Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.39371250
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.38709511
25Toxoplasmosis_Homo sapiens_hsa051451.35392392
26Chemokine signaling pathway_Homo sapiens_hsa040621.30337774
27Hepatitis B_Homo sapiens_hsa051611.29992753
28Leukocyte transendothelial migration_Homo sapiens_hsa046701.27708085
29HTLV-I infection_Homo sapiens_hsa051661.25448052
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.19741742
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.18989495
32Non-homologous end-joining_Homo sapiens_hsa034501.18021905
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.17170657
34Chronic myeloid leukemia_Homo sapiens_hsa052201.13641323
35Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.11971890
36Colorectal cancer_Homo sapiens_hsa052101.11122384
37Influenza A_Homo sapiens_hsa051641.09982610
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08418517
39Shigellosis_Homo sapiens_hsa051311.06404422
40Pancreatic cancer_Homo sapiens_hsa052121.02985136
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.99804396
42Toll-like receptor signaling pathway_Homo sapiens_hsa046200.99374488
43TNF signaling pathway_Homo sapiens_hsa046680.95075835
44Legionellosis_Homo sapiens_hsa051340.91821894
45Prolactin signaling pathway_Homo sapiens_hsa049170.90118642
46Apoptosis_Homo sapiens_hsa042100.89692953
47Viral carcinogenesis_Homo sapiens_hsa052030.87561296
48Epstein-Barr virus infection_Homo sapiens_hsa051690.85176852
49SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84594609
50Thyroid cancer_Homo sapiens_hsa052160.82359639
51Spliceosome_Homo sapiens_hsa030400.81792366
52Malaria_Homo sapiens_hsa051440.80777358
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.80546679
54Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77777512
55Hepatitis C_Homo sapiens_hsa051600.76981854
56Platelet activation_Homo sapiens_hsa046110.76969312
57Tuberculosis_Homo sapiens_hsa051520.66599678
58VEGF signaling pathway_Homo sapiens_hsa043700.65631332
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65474403
60Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.65064303
61Pertussis_Homo sapiens_hsa051330.64212527
62Notch signaling pathway_Homo sapiens_hsa043300.64052293
63Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63056702
64Salmonella infection_Homo sapiens_hsa051320.62347899
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.60648393
66Endometrial cancer_Homo sapiens_hsa052130.57517812
67Non-small cell lung cancer_Homo sapiens_hsa052230.57125586
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.56406451
69Asthma_Homo sapiens_hsa053100.54909673
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53539583
71Small cell lung cancer_Homo sapiens_hsa052220.52936873
72Proteasome_Homo sapiens_hsa030500.50618574
73Staphylococcus aureus infection_Homo sapiens_hsa051500.49174125
74Prostate cancer_Homo sapiens_hsa052150.47450898
75mRNA surveillance pathway_Homo sapiens_hsa030150.46882754
76MAPK signaling pathway_Homo sapiens_hsa040100.46825597
77DNA replication_Homo sapiens_hsa030300.46385880
78p53 signaling pathway_Homo sapiens_hsa041150.46383528
79mTOR signaling pathway_Homo sapiens_hsa041500.44659863
80RNA degradation_Homo sapiens_hsa030180.44609247
81RNA transport_Homo sapiens_hsa030130.41679105
82African trypanosomiasis_Homo sapiens_hsa051430.40132546
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39835663
84FoxO signaling pathway_Homo sapiens_hsa040680.39506093
85Rheumatoid arthritis_Homo sapiens_hsa053230.38865458
86Renal cell carcinoma_Homo sapiens_hsa052110.38831291
87Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38712112
88Regulation of autophagy_Homo sapiens_hsa041400.37505084
89Glycerophospholipid metabolism_Homo sapiens_hsa005640.37101104
90Endocytosis_Homo sapiens_hsa041440.36985269
91Base excision repair_Homo sapiens_hsa034100.35388404
92Circadian rhythm_Homo sapiens_hsa047100.35283259
93MicroRNAs in cancer_Homo sapiens_hsa052060.34804753
94RNA polymerase_Homo sapiens_hsa030200.34108664
95Cyanoamino acid metabolism_Homo sapiens_hsa004600.34004891
96Rap1 signaling pathway_Homo sapiens_hsa040150.33981580
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.31931354
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.31746987
99Insulin resistance_Homo sapiens_hsa049310.30321451
100Sulfur relay system_Homo sapiens_hsa041220.29836058
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29522913
102Type II diabetes mellitus_Homo sapiens_hsa049300.29446211
103Inositol phosphate metabolism_Homo sapiens_hsa005620.28450093
104Adherens junction_Homo sapiens_hsa045200.28367293
105Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28169395
106Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28151692
107One carbon pool by folate_Homo sapiens_hsa006700.27207682
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26569105
109Pathways in cancer_Homo sapiens_hsa052000.25129102
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.24426339
111Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.23555114
112HIF-1 signaling pathway_Homo sapiens_hsa040660.23491326
113Mismatch repair_Homo sapiens_hsa034300.22264858
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.22252049
115Dorso-ventral axis formation_Homo sapiens_hsa043200.21577278
116Phagosome_Homo sapiens_hsa041450.19644482
117Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.15522618
118Lysine degradation_Homo sapiens_hsa003100.15110266
119Lysosome_Homo sapiens_hsa041420.14963718
120Folate biosynthesis_Homo sapiens_hsa007900.13462796
121Prion diseases_Homo sapiens_hsa050200.12085428
122Ras signaling pathway_Homo sapiens_hsa040140.11401109
123Glycerolipid metabolism_Homo sapiens_hsa005610.09910373
124Phospholipase D signaling pathway_Homo sapiens_hsa040720.08831591
125Aldosterone synthesis and secretion_Homo sapiens_hsa049250.07973522
126Drug metabolism - other enzymes_Homo sapiens_hsa009830.06163929
127Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.05866223

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