TRAV17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)9.12530319
2cytidine metabolic process (GO:0046087)8.37861602
3cytidine catabolic process (GO:0006216)8.37861602
4cytidine deamination (GO:0009972)8.37861602
5negative thymic T cell selection (GO:0045060)8.36522363
6positive regulation of gamma-delta T cell activation (GO:0046645)8.30279047
7pyrimidine ribonucleoside catabolic process (GO:0046133)7.77108975
8positive regulation of interleukin-2 biosynthetic process (GO:0045086)7.71714678
9positive T cell selection (GO:0043368)7.56979076
10regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450917.55928110
11DNA deamination (GO:0045006)7.33637325
12regulation of gamma-delta T cell differentiation (GO:0045586)7.14422169
13T cell selection (GO:0045058)7.02971011
14positive thymic T cell selection (GO:0045059)6.97108748
15thymic T cell selection (GO:0045061)6.95601055
16regulation of isotype switching to IgG isotypes (GO:0048302)6.88498588
17positive regulation of interleukin-8 secretion (GO:2000484)6.85387227
18positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.66654308
19regulation of gamma-delta T cell activation (GO:0046643)6.53768136
20positive regulation of monocyte chemotaxis (GO:0090026)6.42494502
21regulation of T cell tolerance induction (GO:0002664)6.29310182
22T cell receptor signaling pathway (GO:0050852)6.17804988
23antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.16426196
24antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.16426196
25response to interleukin-15 (GO:0070672)6.15480313
26regulation of lymphocyte chemotaxis (GO:1901623)6.11111453
27negative regulation of cell killing (GO:0031342)6.02471790
28negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.02471790
29cellular response to interleukin-15 (GO:0071350)6.01218272
30interferon-gamma production (GO:0032609)5.89632164
31lymphocyte chemotaxis (GO:0048247)5.77137487
32chemokine-mediated signaling pathway (GO:0070098)5.74332632
33regulation of interleukin-2 biosynthetic process (GO:0045076)5.56224901
34T cell costimulation (GO:0031295)5.52797179
35lymphocyte costimulation (GO:0031294)5.50398317
36regulation of T cell chemotaxis (GO:0010819)5.46117488
37positive regulation of T cell chemotaxis (GO:0010820)5.46117488
38positive regulation of lymphocyte migration (GO:2000403)5.29555995
39leukocyte aggregation (GO:0070486)5.25777092
40activated T cell proliferation (GO:0050798)5.21463221
41positive regulation of interleukin-2 production (GO:0032743)5.18400026
42positive regulation of tolerance induction (GO:0002645)5.15425347
43antigen processing and presentation of endogenous antigen (GO:0019883)5.09335292
44antigen receptor-mediated signaling pathway (GO:0050851)5.00220159
45regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.94590366
46viral genome replication (GO:0019079)4.91626696
47T cell migration (GO:0072678)4.90727943
48regulation of T cell receptor signaling pathway (GO:0050856)4.86054000
49eosinophil chemotaxis (GO:0048245)4.79079926
50negative regulation by host of viral transcription (GO:0043922)4.76615470
51regulation of alpha-beta T cell proliferation (GO:0046640)4.71287480
52dendritic cell chemotaxis (GO:0002407)4.68205663
53regulation of interleukin-8 secretion (GO:2000482)4.58157971
54positive regulation of alpha-beta T cell proliferation (GO:0046641)4.56177567
55regulation of tolerance induction (GO:0002643)4.49623892
56regulation of regulatory T cell differentiation (GO:0045589)4.49268808
57regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.40905258
58regulation of activation of Janus kinase activity (GO:0010533)4.39383976
59positive regulation of isotype switching (GO:0045830)4.37577032
60regulation of lymphocyte migration (GO:2000401)4.37516768
61regulation of monocyte chemotaxis (GO:0090025)4.35946226
62eosinophil migration (GO:0072677)4.30325799
63negative regulation of execution phase of apoptosis (GO:1900118)4.28223549
64lymphocyte migration (GO:0072676)4.22006569
65positive regulation of defense response to virus by host (GO:0002230)4.18624310
66regulation of interleukin-12 biosynthetic process (GO:0045075)4.15553872
67positive regulation of T cell migration (GO:2000406)4.15095320
68regulation of B cell receptor signaling pathway (GO:0050855)4.13474723
69V(D)J recombination (GO:0033151)4.09523218
70regulation of T cell migration (GO:2000404)4.08397817
71regulation of isotype switching (GO:0045191)4.07181630
72mast cell activation (GO:0045576)4.03755118
73tolerance induction (GO:0002507)3.98708240
74T cell differentiation (GO:0030217)3.97225464
75regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.96022228
76dendritic cell migration (GO:0036336)3.93792873
77regulation of interleukin-2 production (GO:0032663)3.88959462
78regulation of chronic inflammatory response (GO:0002676)3.86967595
79positive regulation of natural killer cell mediated immunity (GO:0002717)3.85721904
80positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.85721904
81macrophage chemotaxis (GO:0048246)3.83492091
82alpha-beta T cell differentiation (GO:0046632)3.82361832
83positive regulation of immunoglobulin mediated immune response (GO:0002891)3.81981261
84positive regulation of B cell mediated immunity (GO:0002714)3.81981261
85negative regulation of T cell receptor signaling pathway (GO:0050860)3.81399863
86negative regulation of T cell mediated immunity (GO:0002710)3.80560349
87positive regulation of humoral immune response (GO:0002922)3.79525801
88negative regulation of type 2 immune response (GO:0002829)3.79338734
89regulation of immunoglobulin mediated immune response (GO:0002889)3.77453902
90positive regulation of DNA recombination (GO:0045911)3.72694184
91alpha-beta T cell activation (GO:0046631)3.72207243
92regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.72100948
93regulation of natural killer cell mediated immunity (GO:0002715)3.72100948
94positive regulation of interleukin-4 production (GO:0032753)3.66599853
95regulation of B cell mediated immunity (GO:0002712)3.63875484
96positive regulation of T cell cytokine production (GO:0002726)3.62470147
97lymph node development (GO:0048535)3.62340651
98T cell activation (GO:0042110)3.58777622
99ncRNA 3-end processing (GO:0043628)3.58292304
100negative regulation of T cell apoptotic process (GO:0070233)3.57761854
101CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.57624243
102regulation of defense response to virus by virus (GO:0050690)3.55645875
103T cell homeostasis (GO:0043029)3.54840119
104regulation of immunoglobulin production (GO:0002637)3.51741876
105pyrimidine nucleoside catabolic process (GO:0046135)3.50697252
106positive regulation of immunoglobulin production (GO:0002639)3.45972494
107adaptation of signaling pathway (GO:0023058)3.45448771
108immune response-activating cell surface receptor signaling pathway (GO:0002429)3.40007585
109negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.39793491
110regulation of interleukin-4 production (GO:0032673)3.38434415
111myeloid dendritic cell activation (GO:0001773)3.36429359
112negative regulation of lymphocyte mediated immunity (GO:0002707)3.34390660
113negative regulation of viral genome replication (GO:0045071)3.34221762
114regulation of response to interferon-gamma (GO:0060330)3.31899699
115regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.29189504
116cellular response to interleukin-4 (GO:0071353)3.28580112
117positive regulation of T cell activation (GO:0050870)3.25765249
118leukocyte cell-cell adhesion (GO:0007159)3.25660659
119positive regulation of calcium-mediated signaling (GO:0050850)3.25202185
120positive regulation of translational initiation (GO:0045948)3.24801916
121actin nucleation (GO:0045010)3.22945817
122ribosomal small subunit assembly (GO:0000028)3.22538605
123cellular defense response (GO:0006968)3.13902018
124regulation of cell killing (GO:0031341)3.12479183
125positive regulation of T-helper 1 type immune response (GO:0002827)3.11209339
126lymphocyte homeostasis (GO:0002260)3.11106407
127positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.10972927
128defense response to protozoan (GO:0042832)3.10342309
129regulation of B cell differentiation (GO:0045577)3.09983941
130production of molecular mediator involved in inflammatory response (GO:0002532)3.08867489
131regulation of calcium-mediated signaling (GO:0050848)3.08767808
132mast cell activation involved in immune response (GO:0002279)3.05568627
133mast cell degranulation (GO:0043303)3.05568627
134positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.04743786
135Arp2/3 complex-mediated actin nucleation (GO:0034314)3.03493119
136regulation of T cell activation (GO:0050863)3.02664088
137positive regulation of lymphocyte mediated immunity (GO:0002708)3.02306248
138natural killer cell activation (GO:0030101)3.02093630
139T cell proliferation (GO:0042098)3.01336841
140T cell lineage commitment (GO:0002360)3.01058221
141positive regulation of granulocyte differentiation (GO:0030854)3.00891474
142regulation of leukocyte mediated cytotoxicity (GO:0001910)2.98936423
143regulation of cellular extravasation (GO:0002691)2.98300684
144negative regulation of viral transcription (GO:0032897)2.98135261
145response to interleukin-4 (GO:0070670)2.97571108
146negative regulation of leukocyte mediated immunity (GO:0002704)2.97297317
147regulation of lymphocyte mediated immunity (GO:0002706)2.97080997
148antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.94224566
149JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.92948238
150negative regulation of bone resorption (GO:0045779)2.92055726
151B cell receptor signaling pathway (GO:0050853)2.91906508
152regulation of thymocyte apoptotic process (GO:0070243)2.90912906
153positive regulation of cell killing (GO:0031343)2.90373984
154myeloid dendritic cell differentiation (GO:0043011)2.90253820
155negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.90152950
156signal complex assembly (GO:0007172)2.89602227

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.17594398
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.33798041
3E2F7_22180533_ChIP-Seq_HELA_Human4.93351171
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.05532481
5MYC_22102868_ChIP-Seq_BL_Human3.99316073
6RUNX_20019798_ChIP-Seq_JUKART_Human3.96063105
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.70714704
8GATA1_22025678_ChIP-Seq_K562_Human3.68855564
9FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.63414096
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.56824427
11STAT4_19710469_ChIP-ChIP_TH1__Mouse3.43295021
12MYB_26560356_Chip-Seq_TH2_Human3.34397995
13IRF8_22096565_ChIP-ChIP_GC-B_Human3.15537372
14MAF_26560356_Chip-Seq_TH1_Human2.99893022
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.87900304
16UTX_26944678_Chip-Seq_JUKART_Human2.86261097
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.83540076
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.70737486
19MYB_26560356_Chip-Seq_TH1_Human2.67859565
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.57587566
21NOTCH1_21737748_ChIP-Seq_TLL_Human2.44731734
22NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.40228766
23MAF_26560356_Chip-Seq_TH2_Human2.26031957
24VDR_21846776_ChIP-Seq_THP-1_Human2.23360099
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18063143
26KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.15558353
27GATA3_27048872_Chip-Seq_THYMUS_Human2.14198121
28RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.12172881
29BP1_19119308_ChIP-ChIP_Hs578T_Human2.01183229
30EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.98173935
31CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.80662269
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.78160635
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.78084052
34RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.75311848
35TCF7_22412390_ChIP-Seq_EML_Mouse1.74222304
36SCL_19346495_ChIP-Seq_HPC-7_Human1.72888180
37SPI1_23547873_ChIP-Seq_NB4_Human1.72779561
38KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.70290767
39VDR_24763502_ChIP-Seq_THP-1_Human1.68298062
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.67992578
41MYB_21317192_ChIP-Seq_ERMYB_Mouse1.67259853
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.67024004
43E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.64418406
44LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.63850109
45CIITA_25753668_ChIP-Seq_RAJI_Human1.59707330
46KDM2B_26808549_Chip-Seq_DND41_Human1.56353446
47NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56082059
48VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.54579061
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53484113
50IRF8_21731497_ChIP-ChIP_J774_Mouse1.48907344
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.48286465
52FOXP3_21729870_ChIP-Seq_TREG_Human1.45407441
53E2F4_17652178_ChIP-ChIP_JURKAT_Human1.45399643
54SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.43627544
55VDR_23849224_ChIP-Seq_CD4+_Human1.42237982
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28111380
57IRF8_27001747_Chip-Seq_BMDM_Mouse1.27675516
58SPI1_23127762_ChIP-Seq_K562_Human1.27601983
59GATA3_26560356_Chip-Seq_TH2_Human1.26858372
60MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.25729306
61BRD4_27068464_Chip-Seq_AML-cells_Mouse1.22509341
62BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.21866561
63FOXM1_23109430_ChIP-Seq_U2OS_Human1.21547133
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.17031736
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16668786
66ELF1_20517297_ChIP-Seq_JURKAT_Human1.15676570
67PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13580766
68MYC_18555785_ChIP-Seq_MESCs_Mouse1.12862588
69NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.12681896
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12547261
71TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.11489002
72MYC_19079543_ChIP-ChIP_MESCs_Mouse1.11040387
73JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.10208344
74KDM2B_26808549_Chip-Seq_SUP-B15_Human1.08673416
75ELK1_19687146_ChIP-ChIP_HELA_Human1.07336172
76HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.07127448
77DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05343914
78SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.03920108
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03833244
80TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.03153534
81KDM2B_26808549_Chip-Seq_JURKAT_Human1.02665277
82MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.01375606
83CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.01264675
84PU_27001747_Chip-Seq_BMDM_Mouse0.99746569
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97363811
86GABP_17652178_ChIP-ChIP_JURKAT_Human0.97229934
87RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96549498
88BCL6_27268052_Chip-Seq_Bcells_Human0.96393109
89FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.96381120
90PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95719846
91XRN2_22483619_ChIP-Seq_HELA_Human0.95570171
92EST1_17652178_ChIP-ChIP_JURKAT_Human0.93752704
93GATA3_26560356_Chip-Seq_TH1_Human0.92586947
94PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90594820
95ERG_20887958_ChIP-Seq_HPC-7_Mouse0.90386957
96ELK3_25401928_ChIP-Seq_HUVEC_Human0.88820075
97FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88482388
98RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87761276
99NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.86591554
100P300_27268052_Chip-Seq_Bcells_Human0.86345213
101PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84116299
102CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.83647651
103EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.83333184
104VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.82699783
105EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.82252582
106PU.1_20513432_ChIP-Seq_Bcells_Mouse0.82208061
107GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.82157767
108CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79332909
109GATA1_22383799_ChIP-Seq_G1ME_Mouse0.77608981
110FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.77356052
111SRF_21415370_ChIP-Seq_HL-1_Mouse0.76521023
112CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75087237
113NCOR1_26117541_ChIP-Seq_K562_Human0.73885396
114SRY_22984422_ChIP-ChIP_TESTIS_Rat0.73299711
115PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.73048216
116PRDM14_20953172_ChIP-Seq_ESCs_Human0.73016433
117TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.72664348
118LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.72336461
119KDM5A_27292631_Chip-Seq_BREAST_Human0.72281938
120CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.72228841
121YY1_21170310_ChIP-Seq_MESCs_Mouse0.71686465
122TAF2_19829295_ChIP-Seq_ESCs_Human0.71502062
123EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.70524037
124GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.69740012
125PCGF2_27294783_Chip-Seq_NPCs_Mouse0.69507650
126ETS1_20019798_ChIP-Seq_JURKAT_Human0.69186356
127MYC_19030024_ChIP-ChIP_MESCs_Mouse0.68923747
128GATA1_19941827_ChIP-Seq_MEL_Mouse0.68352122
129RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.66798403
130STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.64794949
131BCOR_27268052_Chip-Seq_Bcells_Human0.64656161
132FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.64077014
133YY1_22570637_ChIP-Seq_MALME-3M_Human0.63772071
134PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.63181718
135GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.62965654
136GATA6_21074721_ChIP-Seq_CACO-2_Human0.62770486
137GATA3_21867929_ChIP-Seq_TH1_Mouse0.62734092
138FLI1_21867929_ChIP-Seq_CD8_Mouse0.62636247
139TP53_22573176_ChIP-Seq_HFKS_Human0.62089456

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.53191339
2MP0005671_abnormal_response_to4.61822437
3MP0000685_abnormal_immune_system3.66115012
4MP0003300_gastrointestinal_ulcer3.43654422
5MP0002166_altered_tumor_susceptibility3.26032407
6MP0000703_abnormal_thymus_morphology3.25853162
7MP0009333_abnormal_splenocyte_physiolog3.14303512
8MP0002398_abnormal_bone_marrow3.02040048
9MP0001800_abnormal_humoral_immune3.00710166
10MP0001835_abnormal_antigen_presentation2.94611456
11MP0005000_abnormal_immune_tolerance2.84068216
12MP0002420_abnormal_adaptive_immunity2.80618414
13MP0001819_abnormal_immune_cell2.75505377
14MP0001790_abnormal_immune_system2.74824400
15MP0005387_immune_system_phenotype2.74824400
16MP0002723_abnormal_immune_serum2.67133379
17MP0006082_CNS_inflammation2.64423692
18MP0002006_tumorigenesis2.60085871
19MP0003866_abnormal_defecation2.57684469
20MP0002405_respiratory_system_inflammati2.57641638
21MP0002396_abnormal_hematopoietic_system2.53648327
22MP0002722_abnormal_immune_system2.52382763
23MP0000716_abnormal_immune_system2.51985318
24MP0009785_altered_susceptibility_to2.42774793
25MP0002452_abnormal_antigen_presenting2.35758459
26MP0000689_abnormal_spleen_morphology2.31413094
27MP0003436_decreased_susceptibility_to2.26400345
28MP0010155_abnormal_intestine_physiology2.26131396
29MP0005025_abnormal_response_to2.21353499
30MP0004947_skin_inflammation2.12731514
31MP0003724_increased_susceptibility_to2.10405673
32MP0002933_joint_inflammation2.07178550
33MP0001873_stomach_inflammation2.06700518
34MP0002429_abnormal_blood_cell2.04629371
35MP0003329_amyloid_beta_deposits1.90866036
36MP0005166_decreased_susceptibility_to1.90451942
37MP0003303_peritoneal_inflammation1.71876252
38MP0002148_abnormal_hypersensitivity_rea1.71570118
39MP0004808_abnormal_hematopoietic_stem1.63848663
40MP0001845_abnormal_inflammatory_respons1.63731956
41MP0002419_abnormal_innate_immunity1.57145533
42MP0004381_abnormal_hair_follicle1.55522597
43MP0005464_abnormal_platelet_physiology1.54268274
44MP0004510_myositis1.51627162
45MP0001853_heart_inflammation1.41884959
46MP0005058_abnormal_lysosome_morphology1.38175098
47MP0000858_altered_metastatic_potential1.34704975
48MP0002132_abnormal_respiratory_system1.34575159
49MP0000465_gastrointestinal_hemorrhage1.29035950
50MP0003172_abnormal_lysosome_physiology1.24541002
51MP0002693_abnormal_pancreas_physiology1.24336834
52MP0002009_preneoplasia1.23062442
53MP0000569_abnormal_digit_pigmentation1.23029311
54MP0010307_abnormal_tumor_latency1.15731684
55MP0000490_abnormal_crypts_of1.14284348
56MP0004883_abnormal_blood_vessel1.13946297
57MP0002277_abnormal_respiratory_mucosa1.12749457
58MP0005310_abnormal_salivary_gland1.10688677
59MP0002019_abnormal_tumor_incidence1.08657822
60MP0003690_abnormal_glial_cell1.06895205
61MP0005075_abnormal_melanosome_morpholog1.06780468
62MP0003806_abnormal_nucleotide_metabolis1.04308953
63MP0003448_altered_tumor_morphology1.03186255
64MP0001545_abnormal_hematopoietic_system1.00539137
65MP0005397_hematopoietic_system_phenotyp1.00539137
66MP0001851_eye_inflammation0.98747254
67MP0003183_abnormal_peptide_metabolism0.98119387
68MP0001348_abnormal_lacrimal_gland0.96403206
69MP0004145_abnormal_muscle_electrophysio0.96318656
70MP0004782_abnormal_surfactant_physiolog0.96190513
71MP0004233_abnormal_muscle_weight0.95721290
72MP0001542_abnormal_bone_strength0.93909874
73MP0010094_abnormal_chromosome_stability0.93285688
74MP0008469_abnormal_protein_level0.92199090
75MP0001533_abnormal_skeleton_physiology0.91808708
76MP0008057_abnormal_DNA_replication0.91155967
77MP0002876_abnormal_thyroid_physiology0.90083304
78MP0003880_abnormal_central_pattern0.87336370
79MP0003077_abnormal_cell_cycle0.85944956
80MP0002168_other_aberrant_phenotype0.85911839
81MP0002998_abnormal_bone_remodeling0.84612165
82MP0010352_gastrointestinal_tract_polyps0.83561024
83MP0004957_abnormal_blastocyst_morpholog0.80913527
84MP0001984_abnormal_olfaction0.80822602
85MP0002163_abnormal_gland_morphology0.80004087
86MP0002822_catalepsy0.78131532
87MP0010234_abnormal_vibrissa_follicle0.77636576
88MP0005083_abnormal_biliary_tract0.76214969
89MP0001188_hyperpigmentation0.74120948
90MP0002138_abnormal_hepatobiliary_system0.73983947
91MP0001666_abnormal_nutrient_absorption0.73630879
92MP0009643_abnormal_urine_homeostasis0.72357002
93MP0005076_abnormal_cell_differentiation0.71474992
94MP0000372_irregular_coat_pigmentation0.69441027
95MP0000477_abnormal_intestine_morphology0.67514163
96MP0005319_abnormal_enzyme/_coenzyme0.66944204
97MP0003646_muscle_fatigue0.66471115
98MP0003786_premature_aging0.66342547
99MP0009278_abnormal_bone_marrow0.66201837
100MP0005023_abnormal_wound_healing0.65291087
101MP0002136_abnormal_kidney_physiology0.63139117
102MP0009765_abnormal_xenobiotic_induced0.63056559
103MP0003795_abnormal_bone_structure0.60670304
104MP0009763_increased_sensitivity_to0.60481355
105MP0004036_abnormal_muscle_relaxation0.60324268
106MP0003111_abnormal_nucleus_morphology0.59832279
107MP0001663_abnormal_digestive_system0.59183030
108MP0000604_amyloidosis0.58345637
109MP0000343_altered_response_to0.58339546
110MP0001502_abnormal_circadian_rhythm0.57749058
111MP0008961_abnormal_basal_metabolism0.57526823
112MP0008569_lethality_at_weaning0.57199423
113MP0002877_abnormal_melanocyte_morpholog0.55594027
114MP0001243_abnormal_dermal_layer0.55412017
115MP0000609_abnormal_liver_physiology0.53740965
116MP0008260_abnormal_autophagy0.53426281
117MP0000350_abnormal_cell_proliferation0.53114260
118MP0003787_abnormal_imprinting0.52483616
119MP0003137_abnormal_impulse_conducting0.51775840
120MP0008007_abnormal_cellular_replicative0.51139331
121MP0003693_abnormal_embryo_hatching0.50906959
122MP0005645_abnormal_hypothalamus_physiol0.50463236
123MP0005164_abnormal_response_to0.50194180
124MP0000920_abnormal_myelination0.49867745
125MP0001881_abnormal_mammary_gland0.49177711
126MP0001764_abnormal_homeostasis0.49103041
127MP0002095_abnormal_skin_pigmentation0.48027052
128MP0000313_abnormal_cell_death0.47582265
129MP0009764_decreased_sensitivity_to0.47511529
130MP0002928_abnormal_bile_duct0.46176757
131MP0005084_abnormal_gallbladder_morpholo0.45334567
132MP0001191_abnormal_skin_condition0.43618874
133MP0005174_abnormal_tail_pigmentation0.42641646
134MP0000367_abnormal_coat/_hair0.42569025
135MP0002083_premature_death0.42055403
136MP0003045_fibrosis0.40415089
137MP0008770_decreased_survivor_rate0.38196569
138MP0003252_abnormal_bile_duct0.38131810
139MP0008873_increased_physiological_sensi0.38041438
140MP0008877_abnormal_DNA_methylation0.37505502
141MP0006054_spinal_hemorrhage0.36799645

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)9.03437580
2Abnormality of T cell number (HP:0011839)8.64810995
3Severe combined immunodeficiency (HP:0004430)6.68871456
4Combined immunodeficiency (HP:0005387)6.30919271
5Abnormality of T cells (HP:0002843)5.80782379
6Stomatitis (HP:0010280)5.65450585
7Elevated erythrocyte sedimentation rate (HP:0003565)5.57103925
8Eosinophilia (HP:0001880)5.27897339
9Panhypogammaglobulinemia (HP:0003139)5.08568431
10IgG deficiency (HP:0004315)5.06687983
11Abnormality of eosinophils (HP:0001879)4.91188778
12Recurrent viral infections (HP:0004429)4.84127903
13B lymphocytopenia (HP:0010976)4.71780847
14Abnormality of B cell number (HP:0010975)4.71780847
15Recurrent fungal infections (HP:0002841)4.66667743
16Increased IgM level (HP:0003496)4.53333628
17Hypoplasia of the thymus (HP:0000778)4.50918265
18Granulocytopenia (HP:0001913)4.45589119
19Recurrent bronchitis (HP:0002837)4.42741043
20Nasal polyposis (HP:0100582)4.21348036
21Thyroiditis (HP:0100646)4.15015449
22Leukocytosis (HP:0001974)4.14740966
23Chronic otitis media (HP:0000389)4.04319020
24IgM deficiency (HP:0002850)3.76405822
25Joint swelling (HP:0001386)3.70601753
26Autoimmune hemolytic anemia (HP:0001890)3.69396410
27Pustule (HP:0200039)3.56867406
28Chronic diarrhea (HP:0002028)3.54720247
29Eczematoid dermatitis (HP:0000976)3.53241790
30J-shaped sella turcica (HP:0002680)3.50658364
31Recurrent cutaneous fungal infections (HP:0011370)3.45088880
32Chronic mucocutaneous candidiasis (HP:0002728)3.45088880
33Abnormality of the nasal mucosa (HP:0000433)3.43435681
34Acute hepatic failure (HP:0006554)3.42222847
35Aplastic anemia (HP:0001915)3.41452392
36Lymphopenia (HP:0001888)3.36573333
37Recurrent bacterial skin infections (HP:0005406)3.32216305
38Abnormality of cells of the lymphoid lineage (HP:0012140)3.29696411
39Abnormal delayed hypersensitivity skin test (HP:0002963)3.20543565
40Abnormality of T cell physiology (HP:0011840)3.14493152
41Cerebral hypomyelination (HP:0006808)3.06292727
42Myositis (HP:0100614)3.06136749
43Abnormality of the fingertips (HP:0001211)3.03336721
44IgA deficiency (HP:0002720)2.91332031
45Gastrointestinal infarctions (HP:0005244)2.91050369
46Hemiplegia (HP:0002301)2.82698314
47Lymphoma (HP:0002665)2.82283717
48Autoimmune thrombocytopenia (HP:0001973)2.70835276
49Thrombocytosis (HP:0001894)2.65318877
50Hypergammaglobulinemia (HP:0010702)2.63987881
51Abnormality of macrophages (HP:0004311)2.59946456
52Abnormality of the alveolar ridges (HP:0006477)2.57131341
53Meningitis (HP:0001287)2.56980371
54Bronchitis (HP:0012387)2.51803777
55Encephalitis (HP:0002383)2.51396386
56Trigonocephaly (HP:0000243)2.50717467
57Basal cell carcinoma (HP:0002671)2.47978744
58Hemoptysis (HP:0002105)2.47160070
59Volvulus (HP:0002580)2.41873618
60Spontaneous hematomas (HP:0007420)2.38794348
61Carpal bone hypoplasia (HP:0001498)2.38261782
62Gangrene (HP:0100758)2.34973989
63Papilloma (HP:0012740)2.31097681
64Verrucae (HP:0200043)2.31097681
65Palpitations (HP:0001962)2.30781378
66Recurrent sinusitis (HP:0011108)2.28593058
67CNS hypomyelination (HP:0003429)2.26688416
68Amaurosis fugax (HP:0100576)2.23478233
69Chest pain (HP:0100749)2.23386742
70Obstructive lung disease (HP:0006536)2.22639746
71Chronic obstructive pulmonary disease (HP:0006510)2.22639746
72Vasculitis (HP:0002633)2.22624183
73Alveolar cell carcinoma (HP:0006519)2.21454627
74Mediastinal lymphadenopathy (HP:0100721)2.20289508
75Aplasia/Hypoplasia of the thymus (HP:0010515)2.18172642
76Premature ovarian failure (HP:0008209)2.18010505
77Arterial thrombosis (HP:0004420)2.17547399
78Pulmonary infiltrates (HP:0002113)2.15878416
79Renal cortical cysts (HP:0000803)2.15655837
80Increased IgE level (HP:0003212)2.13829601
81Recurrent otitis media (HP:0000403)2.13162790
82Optic neuritis (HP:0100653)2.12186623
83Retrobulbar optic neuritis (HP:0100654)2.12186623
84Epistaxis (HP:0000421)2.11722556
85Abnormal tarsal ossification (HP:0008369)2.11078511
86Delusions (HP:0000746)2.10552849
87Premature graying of hair (HP:0002216)2.08767175
88Abnormal platelet volume (HP:0011876)2.07104779
89Periodontitis (HP:0000704)2.06116708
90Pulmonary embolism (HP:0002204)2.03941973
91Abnormality of the prostate (HP:0008775)2.03397086
92Ureteral stenosis (HP:0000071)2.01881288
93Hypoalbuminemia (HP:0003073)1.98752013
94Abnormal albumin level (HP:0012116)1.98752013
95Stomach cancer (HP:0012126)1.96300152
96Bicuspid aortic valve (HP:0001647)1.95762928
97Increased density of long bones (HP:0006392)1.91528233
98Chronic sinusitis (HP:0011109)1.90420639
99Abnormality of the pleura (HP:0002103)1.90382914
100Gingivitis (HP:0000230)1.89899147
101Neoplasm of the tracheobronchial system (HP:0100552)1.89416531
102Recurrent skin infections (HP:0001581)1.89371154
103Abnormal pupillary function (HP:0007686)1.89305013
104Increased intramyocellular lipid droplets (HP:0012240)1.88626178
105Premature loss of primary teeth (HP:0006323)1.86036842
106Inflammation of the large intestine (HP:0002037)1.85914547
107Dislocated radial head (HP:0003083)1.85848554
108Orchitis (HP:0100796)1.84091060
109Prolonged bleeding time (HP:0003010)1.83732158
110Gastrointestinal inflammation (HP:0004386)1.83659440
111Cellular immunodeficiency (HP:0005374)1.82497275
112Recurrent abscess formation (HP:0002722)1.82316772
113Broad face (HP:0000283)1.80965455
114Gingival bleeding (HP:0000225)1.80711034
115Abnormality of cells of the erythroid lineage (HP:0012130)1.80415122
116Personality changes (HP:0000751)1.80351399
117Pulmonary fibrosis (HP:0002206)1.79240177
118Ureteral obstruction (HP:0006000)1.78725473
119Hypoproteinemia (HP:0003075)1.78594607
120Cheilitis (HP:0100825)1.78367158
121Skin rash (HP:0000988)1.77315347
122Congenital stationary night blindness (HP:0007642)1.77026998
123Keratoconjunctivitis sicca (HP:0001097)1.75906285
124Abnormal number of erythroid precursors (HP:0012131)1.75577712
125Microvesicular hepatic steatosis (HP:0001414)1.75443091
126Hepatitis (HP:0012115)1.75307527
127Abnormality of the radial head (HP:0003995)1.74980260
128Bronchiectasis (HP:0002110)1.71362425
129Anorexia (HP:0002039)1.71069046
130Poor speech (HP:0002465)1.69868387
131Abnormality of oral frenula (HP:0000190)1.69299502
132Agammaglobulinemia (HP:0004432)1.68582331
133Reticulocytopenia (HP:0001896)1.68424248
134Abnormality of the thymus (HP:0000777)1.65479737
135Diplopia (HP:0000651)1.64349763
136Abnormality of binocular vision (HP:0011514)1.64349763

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.95135983
2MAP4K15.75908450
3EIF2AK34.73317712
4ZAP703.42819196
5ITK3.42748473
6JAK32.85564775
7STK102.78972959
8FGFR42.53105026
9BCKDK2.43881216
10MAPKAPK32.30623911
11MAP3K102.30207102
12MAP3K142.24264900
13TYK22.13226022
14LCK2.05991362
15GRK62.04021490
16NLK2.03236453
17IKBKE1.93497496
18LATS11.77739669
19MAP3K71.77226401
20TEC1.71300058
21IRAK31.69388846
22MST41.68099611
23CSK1.61536469
24PDK21.57102673
25FGFR31.56719311
26SYK1.55427412
27JAK11.53670243
28PRKCQ1.52587444
29EEF2K1.51664287
30TESK21.47189064
31PRKCH1.46408879
32NME11.40394472
33PKN21.36940570
34KDR1.33391278
35HCK1.30166321
36NME21.23145677
37LRRK21.19515120
38GRK71.18251373
39BTK1.16543827
40MAP3K121.11839775
41IKBKB1.10121506
42MAP3K131.09452732
43TBK11.03142854
44TNIK1.02825660
45ADRBK20.99048782
46TNK20.98666693
47PRPF4B0.94917348
48DAPK10.92349187
49TRIB30.91863793
50PIK3CG0.90829088
51FES0.87691484
52TAOK20.87654671
53CLK10.82787149
54TYRO30.80055269
55PDGFRB0.79614694
56PRKD20.79481479
57TAOK10.79053404
58JAK20.78368410
59PIM10.77722778
60MAPK70.77583655
61FGFR10.75515648
62CDK90.74114254
63CAMKK20.73575618
64MARK30.73106180
65PASK0.72786361
66TSSK60.72458726
67CHUK0.69577897
68RIPK40.69349426
69LYN0.69235498
70RAF10.69088060
71RPS6KA40.66726392
72MAP2K60.66191065
73CDK40.62623869
74BLK0.61545756
75KIT0.59149398
76CAMKK10.58576860
77CDC70.55830452
78SIK30.55275075
79ZAK0.53464984
80INSR0.53444036
81CDK120.53442921
82VRK20.52425641
83ALK0.52010356
84SIK20.51526143
85PIM20.51392082
86PRKCD0.49827611
87MARK20.49224654
88FYN0.47435072
89TAOK30.47248167
90MELK0.45524386
91MAPK120.44771944
92TESK10.44634329
93ABL10.44555631
94EPHB10.44472916
95MAP2K30.43830681
96MYLK0.43670754
97EPHA30.43435479
98PRKCA0.43118604
99CDK60.41691143
100MAPK40.40591470
101TGFBR20.39797287
102EIF2AK10.39554459
103FRK0.39386894
104BRD40.39379787
105SGK2230.39026298
106SGK4940.39026298
107TIE10.38352272
108MAPKAPK20.37764895
109NEK60.37659967
110PRKCB0.36936935
111PRKD10.36776285
112IGF1R0.36772628
113MAPK110.36549000
114MAP3K80.36520560
115PDK10.34648025
116HIPK20.33949840
117CSF1R0.32669422
118RPS6KA50.32044832
119LIMK10.31122833
120FLT30.30640362
121TGFBR10.29787829
122ILK0.29650640
123OBSCN0.29166440
124MAPK30.29025098
125EIF2AK20.28729270
126ROCK20.28371685
127CAMK2A0.27229537
128FGFR20.27085204
129GRK10.26607033
130RPS6KA60.26603627
131IRAK40.25986018
132STK40.25499602
133MAP3K110.24430772
134PTK2B0.23370324
135NTRK20.23296084
136AURKA0.22397839
137CHEK10.22239410
138NUAK10.20534739
139PRKACA0.20160887
140MAPK90.19339295
141PRKCI0.18605125
142PRKCZ0.16614264
143CSNK2A10.15612920
144INSRR0.15400026
145VRK10.14923243
146DYRK20.14272900
147PIK3CA0.13334890

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.31847424
2T cell receptor signaling pathway_Homo sapiens_hsa046604.68628819
3Measles_Homo sapiens_hsa051623.05825521
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.88803919
5Protein export_Homo sapiens_hsa030602.79453943
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.75269106
7Intestinal immune network for IgA production_Homo sapiens_hsa046722.72809986
8Allograft rejection_Homo sapiens_hsa053302.71076062
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.62799398
10Graft-versus-host disease_Homo sapiens_hsa053322.46156388
11Autoimmune thyroid disease_Homo sapiens_hsa053202.36922257
12Hematopoietic cell lineage_Homo sapiens_hsa046402.30598758
13Antigen processing and presentation_Homo sapiens_hsa046122.15798779
14Leishmaniasis_Homo sapiens_hsa051401.96853268
15Viral myocarditis_Homo sapiens_hsa054161.90841558
16Ribosome_Homo sapiens_hsa030101.71205018
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.71127974
18Osteoclast differentiation_Homo sapiens_hsa043801.68003898
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61749624
20Jak-STAT signaling pathway_Homo sapiens_hsa046301.57703407
21B cell receptor signaling pathway_Homo sapiens_hsa046621.51980800
22Non-homologous end-joining_Homo sapiens_hsa034501.50383080
23Herpes simplex infection_Homo sapiens_hsa051681.46181283
24Acute myeloid leukemia_Homo sapiens_hsa052211.43151003
25Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.36034713
26Shigellosis_Homo sapiens_hsa051311.35941860
27NOD-like receptor signaling pathway_Homo sapiens_hsa046211.35284161
28Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.34787659
29Type I diabetes mellitus_Homo sapiens_hsa049401.34777989
30Toxoplasmosis_Homo sapiens_hsa051451.33677721
31Asthma_Homo sapiens_hsa053101.31563570
32Hepatitis B_Homo sapiens_hsa051611.29314803
33HTLV-I infection_Homo sapiens_hsa051661.27253346
34Chemokine signaling pathway_Homo sapiens_hsa040621.24201197
35Pancreatic cancer_Homo sapiens_hsa052121.19980076
36Spliceosome_Homo sapiens_hsa030401.19477123
37Leukocyte transendothelial migration_Homo sapiens_hsa046701.18447028
38Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.18285207
39Colorectal cancer_Homo sapiens_hsa052101.12787173
40Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.12361267
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.11846492
42Chronic myeloid leukemia_Homo sapiens_hsa052201.11720004
43Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09990357
44Epstein-Barr virus infection_Homo sapiens_hsa051690.96838674
45Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.94857108
46Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.93697969
47TNF signaling pathway_Homo sapiens_hsa046680.90092077
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88770475
49Influenza A_Homo sapiens_hsa051640.87706032
50DNA replication_Homo sapiens_hsa030300.87337251
51Caffeine metabolism_Homo sapiens_hsa002320.86626885
52Apoptosis_Homo sapiens_hsa042100.85277857
53Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.84968133
54Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84307297
55Viral carcinogenesis_Homo sapiens_hsa052030.84131124
56Prion diseases_Homo sapiens_hsa050200.73040097
57Hepatitis C_Homo sapiens_hsa051600.71369622
58Prolactin signaling pathway_Homo sapiens_hsa049170.71112080
59Oxidative phosphorylation_Homo sapiens_hsa001900.70388113
60Sulfur relay system_Homo sapiens_hsa041220.69993342
61Platelet activation_Homo sapiens_hsa046110.68806986
62Parkinsons disease_Homo sapiens_hsa050120.67599626
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66696750
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.66444748
65Regulation of autophagy_Homo sapiens_hsa041400.65607729
66RNA degradation_Homo sapiens_hsa030180.64538934
67Legionellosis_Homo sapiens_hsa051340.64102844
68VEGF signaling pathway_Homo sapiens_hsa043700.58343217
69Small cell lung cancer_Homo sapiens_hsa052220.56896366
70Prostate cancer_Homo sapiens_hsa052150.56688329
71AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55336879
72Purine metabolism_Homo sapiens_hsa002300.55239186
73Non-small cell lung cancer_Homo sapiens_hsa052230.54702468
74Endometrial cancer_Homo sapiens_hsa052130.54548647
75Mismatch repair_Homo sapiens_hsa034300.53697469
76Salmonella infection_Homo sapiens_hsa051320.53115964
77Thyroid cancer_Homo sapiens_hsa052160.52328701
78African trypanosomiasis_Homo sapiens_hsa051430.50511276
79Base excision repair_Homo sapiens_hsa034100.49816827
80RNA transport_Homo sapiens_hsa030130.48846682
81Tuberculosis_Homo sapiens_hsa051520.48550770
82mRNA surveillance pathway_Homo sapiens_hsa030150.48246985
83One carbon pool by folate_Homo sapiens_hsa006700.47611619
84Staphylococcus aureus infection_Homo sapiens_hsa051500.45022059
85Cell cycle_Homo sapiens_hsa041100.44811661
86Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44367379
87MAPK signaling pathway_Homo sapiens_hsa040100.43809223
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43698774
89p53 signaling pathway_Homo sapiens_hsa041150.42947550
90Phototransduction_Homo sapiens_hsa047440.41648508
91Nitrogen metabolism_Homo sapiens_hsa009100.41555435
92Homologous recombination_Homo sapiens_hsa034400.40811555
93Notch signaling pathway_Homo sapiens_hsa043300.40728541
94Endocytosis_Homo sapiens_hsa041440.40035620
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.39402250
96Malaria_Homo sapiens_hsa051440.39166648
97Adherens junction_Homo sapiens_hsa045200.36907081
98Pertussis_Homo sapiens_hsa051330.36062475
99Rap1 signaling pathway_Homo sapiens_hsa040150.35895668
100Sulfur metabolism_Homo sapiens_hsa009200.34326362
101RNA polymerase_Homo sapiens_hsa030200.33787024
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.31114862
103FoxO signaling pathway_Homo sapiens_hsa040680.30479779
104Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.30025293
105Pancreatic secretion_Homo sapiens_hsa049720.30024089
106Alzheimers disease_Homo sapiens_hsa050100.26393976
107Renal cell carcinoma_Homo sapiens_hsa052110.26266925
108Proteasome_Homo sapiens_hsa030500.25765383
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.24623688
110Thyroid hormone signaling pathway_Homo sapiens_hsa049190.24066036
111Pathways in cancer_Homo sapiens_hsa052000.23803416
112Rheumatoid arthritis_Homo sapiens_hsa053230.23182213
113MicroRNAs in cancer_Homo sapiens_hsa052060.22833253
114Systemic lupus erythematosus_Homo sapiens_hsa053220.21482480
115Peroxisome_Homo sapiens_hsa041460.20475854
116Huntingtons disease_Homo sapiens_hsa050160.20178925
117Pyrimidine metabolism_Homo sapiens_hsa002400.20162588
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.18970556
119Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.18714531
120Glycosaminoglycan degradation_Homo sapiens_hsa005310.18211299
121Mineral absorption_Homo sapiens_hsa049780.17961147
122Calcium signaling pathway_Homo sapiens_hsa040200.17956023
123Ether lipid metabolism_Homo sapiens_hsa005650.17677617
124Salivary secretion_Homo sapiens_hsa049700.16551197
125Linoleic acid metabolism_Homo sapiens_hsa005910.15961370
126Nucleotide excision repair_Homo sapiens_hsa034200.15952357
127Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.15653330
128Ras signaling pathway_Homo sapiens_hsa040140.15437708
129Inositol phosphate metabolism_Homo sapiens_hsa005620.13827863
130Vascular smooth muscle contraction_Homo sapiens_hsa042700.11706703
131Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.11511805
132cAMP signaling pathway_Homo sapiens_hsa040240.10037311
133Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.08576934
134Collecting duct acid secretion_Homo sapiens_hsa049660.06570361
135Arachidonic acid metabolism_Homo sapiens_hsa005900.05985004
136Cyanoamino acid metabolism_Homo sapiens_hsa004600.05641174
137Phagosome_Homo sapiens_hsa041450.05097887
138Glycerolipid metabolism_Homo sapiens_hsa005610.03384719
139Cardiac muscle contraction_Homo sapiens_hsa042600.03041595
140Cholinergic synapse_Homo sapiens_hsa047250.02414729

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