TRAV19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)8.77814822
2negative thymic T cell selection (GO:0045060)8.41439335
3positive regulation of gamma-delta T cell activation (GO:0046645)7.15197075
4thymic T cell selection (GO:0045061)7.00518745
5positive thymic T cell selection (GO:0045059)6.96083688
6positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.88850943
7positive T cell selection (GO:0043368)6.82212394
8T cell selection (GO:0045058)6.65487914
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.51627120
10negative regulation of cell killing (GO:0031342)6.51627120
11regulation of isotype switching to IgG isotypes (GO:0048302)6.50528917
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.38235607
13regulation of gamma-delta T cell differentiation (GO:0045586)6.34734981
14interferon-gamma production (GO:0032609)6.34291279
15regulation of T cell tolerance induction (GO:0002664)6.10261356
16antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.09875487
17antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.09875487
18positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.89475932
19regulation of gamma-delta T cell activation (GO:0046643)5.66439232
20response to interleukin-15 (GO:0070672)5.66390548
21T cell receptor signaling pathway (GO:0050852)5.51132218
22cellular response to interleukin-15 (GO:0071350)5.42369318
23leukocyte aggregation (GO:0070486)5.24948507
24T cell migration (GO:0072678)5.22178832
25T cell costimulation (GO:0031295)5.09583527
26regulation of interleukin-2 biosynthetic process (GO:0045076)5.09191893
27positive regulation of tolerance induction (GO:0002645)5.06497907
28antigen processing and presentation of endogenous antigen (GO:0019883)5.05280905
29lymphocyte costimulation (GO:0031294)5.02127468
30activated T cell proliferation (GO:0050798)4.92937803
31regulation of alpha-beta T cell proliferation (GO:0046640)4.83529823
32negative regulation of execution phase of apoptosis (GO:1900118)4.76669264
33positive regulation of alpha-beta T cell proliferation (GO:0046641)4.56795720
34lymphocyte chemotaxis (GO:0048247)4.55300735
35positive regulation of interleukin-2 production (GO:0032743)4.49823592
36antigen receptor-mediated signaling pathway (GO:0050851)4.42612014
37regulation of interleukin-12 biosynthetic process (GO:0045075)4.39803314
38regulation of tolerance induction (GO:0002643)4.39455894
39regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.34021000
40positive regulation of isotype switching (GO:0045830)4.24943226
41regulation of regulatory T cell differentiation (GO:0045589)4.23889506
42regulation of T cell receptor signaling pathway (GO:0050856)4.07838594
43T cell mediated immunity (GO:0002456)4.01876187
44regulation of isotype switching (GO:0045191)3.97383906
45negative regulation of T cell mediated immunity (GO:0002710)3.97080328
46positive regulation of cell killing (GO:0031343)3.91880557
47adaptation of signaling pathway (GO:0023058)3.89326727
48regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.88231309
49respiratory burst (GO:0045730)3.80476606
50positive regulation of humoral immune response (GO:0002922)3.78344884
51negative regulation of leukocyte mediated immunity (GO:0002704)3.78204099
52positive regulation of B cell mediated immunity (GO:0002714)3.75531693
53positive regulation of immunoglobulin mediated immune response (GO:0002891)3.75531693
54positive regulation of natural killer cell mediated immunity (GO:0002717)3.74210086
55positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.74210086
56regulation of cell killing (GO:0031341)3.72854701
57chemokine-mediated signaling pathway (GO:0070098)3.72827871
58sequestering of actin monomers (GO:0042989)3.72815251
59positive regulation of T cell chemotaxis (GO:0010820)3.69996219
60regulation of T cell chemotaxis (GO:0010819)3.69996219
61regulation of B cell receptor signaling pathway (GO:0050855)3.69863228
62regulation of natural killer cell mediated immunity (GO:0002715)3.68412943
63regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.68412943
64Arp2/3 complex-mediated actin nucleation (GO:0034314)3.67558842
65tolerance induction (GO:0002507)3.67492579
66negative regulation of phagocytosis (GO:0050765)3.66199135
67alpha-beta T cell activation (GO:0046631)3.63750731
68alpha-beta T cell differentiation (GO:0046632)3.61475796
69positive regulation of DNA recombination (GO:0045911)3.60091492
70cellular defense response (GO:0006968)3.59737033
71dendritic cell chemotaxis (GO:0002407)3.59344439
72pyrimidine ribonucleoside catabolic process (GO:0046133)3.59028067
73positive regulation of T cell mediated cytotoxicity (GO:0001916)3.58635837
74regulation of activation of Janus kinase activity (GO:0010533)3.58015408
75regulation of immunoglobulin mediated immune response (GO:0002889)3.57151165
76positive regulation of uterine smooth muscle contraction (GO:0070474)3.56775671
77ribosomal small subunit assembly (GO:0000028)3.56159911
78T cell differentiation (GO:0030217)3.54744362
79mast cell activation (GO:0045576)3.54171077
80cytidine metabolic process (GO:0046087)3.48961440
81cytidine catabolic process (GO:0006216)3.48961440
82cytidine deamination (GO:0009972)3.48961440
83positive regulation of interleukin-4 production (GO:0032753)3.44623923
84regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.43175366
85regulation of B cell mediated immunity (GO:0002712)3.42994753
86cytolysis (GO:0019835)3.42277397
87regulation of T cell mediated cytotoxicity (GO:0001914)3.42248679
88regulation of immunoglobulin production (GO:0002637)3.41080499
89positive regulation of natural killer cell differentiation (GO:0032825)3.39520581
90antigen processing and presentation via MHC class Ib (GO:0002475)3.36059279
91B cell receptor signaling pathway (GO:0050853)3.35530460
92regulation of interleukin-2 production (GO:0032663)3.35276180
93NIK/NF-kappaB signaling (GO:0038061)3.34535165
94regulation of B cell differentiation (GO:0045577)3.33437756
95regulation of defense response to virus by virus (GO:0050690)3.32679701
96regulation of calcium-mediated signaling (GO:0050848)3.32366562
97T cell activation (GO:0042110)3.29736112
98regulation of response to interferon-gamma (GO:0060330)3.29198989
99negative regulation of T cell apoptotic process (GO:0070233)3.28962696
100signal complex assembly (GO:0007172)3.28054594
101viral transcription (GO:0019083)3.27800657
102positive regulation of immunoglobulin production (GO:0002639)3.26967971
103regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.26691233
104positive regulation of B cell differentiation (GO:0045579)3.23863113
105leukocyte cell-cell adhesion (GO:0007159)3.21799879
106dendritic cell migration (GO:0036336)3.19952648
107negative regulation of T cell receptor signaling pathway (GO:0050860)3.19852602
108regulation of interleukin-4 production (GO:0032673)3.19708689
109negative regulation of lymphocyte mediated immunity (GO:0002707)3.19304000
110negative regulation of type 2 immune response (GO:0002829)3.17901542
111CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.17760436
112cellular response to interleukin-4 (GO:0071353)3.16507592
113translational termination (GO:0006415)3.15652215
114regulation of response to tumor cell (GO:0002834)3.12070286
115positive regulation of response to tumor cell (GO:0002836)3.12070286
116positive regulation of immune response to tumor cell (GO:0002839)3.12070286
117regulation of immune response to tumor cell (GO:0002837)3.12070286
118positive regulation of monocyte chemotaxis (GO:0090026)3.11971823
119regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.11218038
120T cell proliferation (GO:0042098)3.10713166
121actin nucleation (GO:0045010)3.10237714
122negative regulation of interleukin-12 production (GO:0032695)3.09822656
123negative regulation of stress fiber assembly (GO:0051497)3.09794122
124ribosomal small subunit biogenesis (GO:0042274)3.07834533
125positive regulation of lymphocyte mediated immunity (GO:0002708)3.05845262
126immune response-activating cell surface receptor signaling pathway (GO:0002429)3.04812430
127positive regulation of granulocyte differentiation (GO:0030854)3.03561102
128positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.02701215
129maturation of SSU-rRNA (GO:0030490)3.02152844
130positive regulation of calcium-mediated signaling (GO:0050850)3.00447927
131positive regulation of T cell activation (GO:0050870)2.98994902
132lymphocyte migration (GO:0072676)2.98911779
133regulation of leukocyte mediated cytotoxicity (GO:0001910)2.97226973
134T cell homeostasis (GO:0043029)2.95012060
135DNA deamination (GO:0045006)2.94354651
136negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.93155842
137positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.90180836
138natural killer cell activation (GO:0030101)2.85309858
139positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.84781501
140regulation of type I interferon-mediated signaling pathway (GO:0060338)2.83278955
141response to interleukin-4 (GO:0070670)2.82457700
142regulation of alpha-beta T cell activation (GO:0046634)2.79870785

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.05773446
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.50289259
3E2F7_22180533_ChIP-Seq_HELA_Human4.99622187
4MYC_22102868_ChIP-Seq_BL_Human3.71310706
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.22659974
6FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.16896037
7RUNX_20019798_ChIP-Seq_JUKART_Human3.14988416
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.06778777
9STAT4_19710469_ChIP-ChIP_TH1__Mouse3.04799005
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.03206615
11MYB_26560356_Chip-Seq_TH2_Human2.94022408
12MAF_26560356_Chip-Seq_TH1_Human2.68778394
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.62344107
14UTX_26944678_Chip-Seq_JUKART_Human2.50244623
15NOTCH1_21737748_ChIP-Seq_TLL_Human2.49278267
16MYB_26560356_Chip-Seq_TH1_Human2.45875675
17IRF8_22096565_ChIP-ChIP_GC-B_Human2.41646351
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.41529641
19SMAD_19615063_ChIP-ChIP_OVARY_Human2.37246278
20MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.37102775
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.31183849
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.19770826
23EGR1_19374776_ChIP-ChIP_THP-1_Human2.17359725
24MAF_26560356_Chip-Seq_TH2_Human2.16307570
25MYC_18555785_ChIP-Seq_MESCs_Mouse2.09758662
26ELF1_17652178_ChIP-ChIP_JURKAT_Human2.08153957
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.06357607
28VDR_21846776_ChIP-Seq_THP-1_Human2.06195997
29CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.92533992
30KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.90073570
31RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.89210052
32FOXM1_23109430_ChIP-Seq_U2OS_Human1.87297168
33GATA3_27048872_Chip-Seq_THYMUS_Human1.85019846
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.83999438
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.70880562
36VDR_23849224_ChIP-Seq_CD4+_Human1.69016405
37CIITA_25753668_ChIP-Seq_RAJI_Human1.66422550
38SPI1_23547873_ChIP-Seq_NB4_Human1.65034410
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.63093818
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.62624599
41TCF7_22412390_ChIP-Seq_EML_Mouse1.62012219
42KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.61883092
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.60810898
44CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.59867400
45FOXP3_21729870_ChIP-Seq_TREG_Human1.57932758
46ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.55516502
47LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.54970959
48EST1_17652178_ChIP-ChIP_JURKAT_Human1.54228749
49E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.53884659
50KDM2B_26808549_Chip-Seq_DND41_Human1.51040444
51BP1_19119308_ChIP-ChIP_Hs578T_Human1.49379729
52IRF8_21731497_ChIP-ChIP_J774_Mouse1.48605909
53GABP_17652178_ChIP-ChIP_JURKAT_Human1.46721042
54LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.45212853
55XRN2_22483619_ChIP-Seq_HELA_Human1.44278632
56MYB_21317192_ChIP-Seq_ERMYB_Mouse1.39892314
57MYC_19030024_ChIP-ChIP_MESCs_Mouse1.32828131
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31656904
59GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.29737166
60ETS1_20019798_ChIP-Seq_JURKAT_Human1.28646451
61VDR_24763502_ChIP-Seq_THP-1_Human1.25573428
62NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.25042358
63ELK1_19687146_ChIP-ChIP_HELA_Human1.24324340
64MYC_18358816_ChIP-ChIP_MESCs_Mouse1.18091570
65BRD4_27068464_Chip-Seq_AML-cells_Mouse1.17384587
66TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15074225
67SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.14691222
68RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.14285070
69FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.13106902
70MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.10601963
71KDM2B_26808549_Chip-Seq_SUP-B15_Human1.07728538
72IRF8_27001747_Chip-Seq_BMDM_Mouse1.07051657
73SCL_19346495_ChIP-Seq_HPC-7_Human1.06251911
74RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.05612641
75BCL6_27268052_Chip-Seq_Bcells_Human1.05455298
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.05394300
77JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.04203273
78GATA3_26560356_Chip-Seq_TH2_Human1.03641458
79NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.03384656
80KDM5A_27292631_Chip-Seq_BREAST_Human1.01676234
81GATA2_22383799_ChIP-Seq_G1ME_Mouse1.00974340
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00208595
83SPI1_23127762_ChIP-Seq_K562_Human0.99975438
84ERG_20887958_ChIP-Seq_HPC-7_Mouse0.99709424
85TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.98784257
86ELK3_25401928_ChIP-Seq_HUVEC_Human0.98470898
87NELFA_20434984_ChIP-Seq_ESCs_Mouse0.98184852
88EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.97537184
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96311467
90KDM2B_26808549_Chip-Seq_JURKAT_Human0.96014287
91HOXB4_20404135_ChIP-ChIP_EML_Mouse0.94138969
92FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92746516
93SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.92491858
94VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92324517
95CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91823042
96CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.89348128
97GABP_19822575_ChIP-Seq_HepG2_Human0.88631553
98VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.88600742
99VDR_22108803_ChIP-Seq_LS180_Human0.88374991
100SRY_22984422_ChIP-ChIP_TESTIS_Rat0.88094375
101BCOR_27268052_Chip-Seq_Bcells_Human0.87256573
102PU_27001747_Chip-Seq_BMDM_Mouse0.87104294
103PU.1_20513432_ChIP-Seq_Bcells_Mouse0.86737362
104DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85529297
105RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.85490173
106ELF1_20517297_ChIP-Seq_JURKAT_Human0.85408466
107PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.84691695
108FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.83852537
109STAT3_1855785_ChIP-Seq_MESCs_Mouse0.83477574
110CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.82984634
111TTF2_22483619_ChIP-Seq_HELA_Human0.82871802
112NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.82616367
113PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80888203
114RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.80148021
115SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80092113
116NCOR1_26117541_ChIP-Seq_K562_Human0.79997567
117CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79992360
118YY1_22570637_ChIP-Seq_MALME-3M_Human0.79699470
119CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79554141
120POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.79544569
121RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79422095
122CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79315637
123NANOG_18555785_ChIP-Seq_MESCs_Mouse0.78278269
124CREB1_15753290_ChIP-ChIP_HEK293T_Human0.77909268
125GATA3_26560356_Chip-Seq_TH1_Human0.75264583
126NANOG_20526341_ChIP-Seq_ESCs_Human0.74758993
127SPI1_20517297_ChIP-Seq_HL60_Human0.74609659
128CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.67462170
129FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.66695324
130TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.66401251
131P300_27268052_Chip-Seq_Bcells_Human0.65036071
132PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.64501584
133OCT4_20526341_ChIP-Seq_ESCs_Human0.63489338
134VDR_24787735_ChIP-Seq_THP-1_Human0.63185850
135GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.62887360
136ERA_21632823_ChIP-Seq_H3396_Human0.61735917
137TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.60777418
138GATA1_22383799_ChIP-Seq_G1ME_Mouse0.60705210
139PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.60681783
140BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.60412549
141CTCF_27219007_Chip-Seq_ERYTHROID_Human0.60343828

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.44850263
2MP0005671_abnormal_response_to4.50362023
3MP0000685_abnormal_immune_system3.57905549
4MP0009333_abnormal_splenocyte_physiolog3.28480423
5MP0000703_abnormal_thymus_morphology3.07589838
6MP0001800_abnormal_humoral_immune3.06001985
7MP0002398_abnormal_bone_marrow2.96287206
8MP0001835_abnormal_antigen_presentation2.81667242
9MP0002420_abnormal_adaptive_immunity2.80572131
10MP0005000_abnormal_immune_tolerance2.76361962
11MP0002166_altered_tumor_susceptibility2.75967137
12MP0001819_abnormal_immune_cell2.75759818
13MP0001790_abnormal_immune_system2.70886175
14MP0005387_immune_system_phenotype2.70886175
15MP0002723_abnormal_immune_serum2.70083598
16MP0002405_respiratory_system_inflammati2.65322570
17MP0003436_decreased_susceptibility_to2.54330386
18MP0002722_abnormal_immune_system2.50294570
19MP0000716_abnormal_immune_system2.50105617
20MP0006082_CNS_inflammation2.46309611
21MP0002452_abnormal_antigen_presenting2.38966411
22MP0000689_abnormal_spleen_morphology2.38565840
23MP0002396_abnormal_hematopoietic_system2.37464565
24MP0003866_abnormal_defecation2.32761070
25MP0002006_tumorigenesis2.31200306
26MP0003300_gastrointestinal_ulcer2.30089824
27MP0005025_abnormal_response_to2.26373835
28MP0001873_stomach_inflammation2.21417600
29MP0003011_delayed_dark_adaptation2.17712573
30MP0009785_altered_susceptibility_to2.16067828
31MP0002429_abnormal_blood_cell2.05943453
32MP0010155_abnormal_intestine_physiology2.05469817
33MP0004947_skin_inflammation1.93777449
34MP0003303_peritoneal_inflammation1.88291860
35MP0002933_joint_inflammation1.84405486
36MP0003724_increased_susceptibility_to1.80810182
37MP0008057_abnormal_DNA_replication1.69226595
38MP0004957_abnormal_blastocyst_morpholog1.68408441
39MP0001853_heart_inflammation1.63310913
40MP0000858_altered_metastatic_potential1.62597279
41MP0002148_abnormal_hypersensitivity_rea1.61680164
42MP0001845_abnormal_inflammatory_respons1.52303154
43MP0004808_abnormal_hematopoietic_stem1.51873568
44MP0004381_abnormal_hair_follicle1.48074314
45MP0002419_abnormal_innate_immunity1.46666910
46MP0003693_abnormal_embryo_hatching1.44473203
47MP0005451_abnormal_body_composition1.42445933
48MP0005464_abnormal_platelet_physiology1.42176897
49MP0003077_abnormal_cell_cycle1.40491745
50MP0004510_myositis1.36590217
51MP0003690_abnormal_glial_cell1.36113815
52MP0003191_abnormal_cellular_cholesterol1.33873010
53MP0003448_altered_tumor_morphology1.31626701
54MP0010352_gastrointestinal_tract_polyps1.29508747
55MP0010094_abnormal_chromosome_stability1.24602677
56MP0000490_abnormal_crypts_of1.24538905
57MP0005166_decreased_susceptibility_to1.23396109
58MP0003806_abnormal_nucleotide_metabolis1.23087134
59MP0002019_abnormal_tumor_incidence1.22115688
60MP0005075_abnormal_melanosome_morpholog1.21913085
61MP0002277_abnormal_respiratory_mucosa1.20444956
62MP0003111_abnormal_nucleus_morphology1.14704053
63MP0002132_abnormal_respiratory_system1.12385812
64MP0005310_abnormal_salivary_gland1.09655775
65MP0000465_gastrointestinal_hemorrhage1.09286556
66MP0005023_abnormal_wound_healing1.08361637
67MP0008961_abnormal_basal_metabolism0.98489785
68MP0005379_endocrine/exocrine_gland_phen0.96441522
69MP0001533_abnormal_skeleton_physiology0.92403284
70MP0008260_abnormal_autophagy0.91264292
71MP0008469_abnormal_protein_level0.89445031
72MP0001545_abnormal_hematopoietic_system0.87698528
73MP0005397_hematopoietic_system_phenotyp0.87698528
74MP0002693_abnormal_pancreas_physiology0.85934243
75MP0003329_amyloid_beta_deposits0.85756468
76MP0008058_abnormal_DNA_repair0.83318704
77MP0005076_abnormal_cell_differentiation0.80836028
78MP0000350_abnormal_cell_proliferation0.80214686
79MP0002009_preneoplasia0.79071847
80MP0001851_eye_inflammation0.76133237
81MP0001730_embryonic_growth_arrest0.75957762
82MP0003183_abnormal_peptide_metabolism0.75547421
83MP0001542_abnormal_bone_strength0.73342255
84MP0002163_abnormal_gland_morphology0.72810098
85MP0009764_decreased_sensitivity_to0.72522884
86MP0009765_abnormal_xenobiotic_induced0.71686444
87MP0000477_abnormal_intestine_morphology0.71129958
88MP0003252_abnormal_bile_duct0.70732461
89MP0001348_abnormal_lacrimal_gland0.70453426
90MP0008007_abnormal_cellular_replicative0.70404888
91MP0004883_abnormal_blood_vessel0.70346895
92MP0002998_abnormal_bone_remodeling0.67073773
93MP0002138_abnormal_hepatobiliary_system0.66946495
94MP0000313_abnormal_cell_death0.64940757
95MP0009763_increased_sensitivity_to0.64407915
96MP0004185_abnormal_adipocyte_glucose0.64094705
97MP0005645_abnormal_hypothalamus_physiol0.63935393
98MP0000920_abnormal_myelination0.63115585
99MP0004130_abnormal_muscle_cell0.62856605
100MP0001765_abnormal_ion_homeostasis0.61962197
101MP0002168_other_aberrant_phenotype0.61919191
102MP0000604_amyloidosis0.60988865
103MP0001243_abnormal_dermal_layer0.57969961
104MP0002086_abnormal_extraembryonic_tissu0.57359310
105MP0009643_abnormal_urine_homeostasis0.56934263
106MP0003137_abnormal_impulse_conducting0.55810686
107MP0003795_abnormal_bone_structure0.54861369
108MP0002080_prenatal_lethality0.51590365
109MP0003045_fibrosis0.51472628
110MP0000609_abnormal_liver_physiology0.51111475
111MP0005164_abnormal_response_to0.50344772
112MP0005319_abnormal_enzyme/_coenzyme0.50302489
113MP0008872_abnormal_physiological_respon0.50046586
114MP0008873_increased_physiological_sensi0.49227756
115MP0003075_altered_response_to0.48563282
116MP0004145_abnormal_muscle_electrophysio0.47427930
117MP0008770_decreased_survivor_rate0.46260821
118MP0002088_abnormal_embryonic_growth/wei0.45490959
119MP0001216_abnormal_epidermal_layer0.45315901
120MP0009642_abnormal_blood_homeostasis0.44784517
121MP0003091_abnormal_cell_migration0.44725061
122MP0003984_embryonic_growth_retardation0.44380147
123MP0005380_embryogenesis_phenotype0.44090454
124MP0001672_abnormal_embryogenesis/_devel0.44090454
125MP0003786_premature_aging0.43864928
126MP0005390_skeleton_phenotype0.42645954
127MP0002837_dystrophic_cardiac_calcinosis0.42433648
128MP0003646_muscle_fatigue0.42185873
129MP0002822_catalepsy0.41669725
130MP0001697_abnormal_embryo_size0.41656350
131MP0000372_irregular_coat_pigmentation0.41526656
132MP0002136_abnormal_kidney_physiology0.41335008
133MP0003453_abnormal_keratinocyte_physiol0.40689122
134MP0002083_premature_death0.40604844
135MP0000249_abnormal_blood_vessel0.40406598
136MP0008569_lethality_at_weaning0.36585804

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)8.75158892
2Abnormality of T cell number (HP:0011839)8.36319645
3Stomatitis (HP:0010280)6.09506915
4Abnormality of T cells (HP:0002843)5.95968441
5Combined immunodeficiency (HP:0005387)5.87684517
6Severe combined immunodeficiency (HP:0004430)5.84684439
7Elevated erythrocyte sedimentation rate (HP:0003565)5.81775956
8Aplastic anemia (HP:0001915)5.22088346
9Nasal polyposis (HP:0100582)4.70577586
10Recurrent bronchitis (HP:0002837)4.67618807
11Panhypogammaglobulinemia (HP:0003139)4.66344097
12Recurrent viral infections (HP:0004429)4.58187729
13Abnormality of macrophages (HP:0004311)4.51557231
14IgG deficiency (HP:0004315)4.44486179
15Recurrent fungal infections (HP:0002841)4.34170030
16Acute hepatic failure (HP:0006554)4.29219297
17Chronic otitis media (HP:0000389)4.20756337
18IgM deficiency (HP:0002850)4.16317177
19Abnormality of eosinophils (HP:0001879)4.01905167
20Eosinophilia (HP:0001880)4.01242906
21Pustule (HP:0200039)3.88438767
22Increased IgM level (HP:0003496)3.85726141
23Abnormality of the nasal mucosa (HP:0000433)3.83734305
24Granulocytopenia (HP:0001913)3.72064086
25Eczematoid dermatitis (HP:0000976)3.60819519
26Recurrent bacterial skin infections (HP:0005406)3.60495760
27Abnormality of T cell physiology (HP:0011840)3.54608440
28Leukocytosis (HP:0001974)3.53061798
29Joint swelling (HP:0001386)3.51781105
30B lymphocytopenia (HP:0010976)3.46035040
31Abnormality of B cell number (HP:0010975)3.46035040
32Abnormal delayed hypersensitivity skin test (HP:0002963)3.45677111
33Lymphopenia (HP:0001888)3.42735325
34Basal cell carcinoma (HP:0002671)3.42354498
35Abnormality of cells of the lymphoid lineage (HP:0012140)3.36614974
36Abnormality of the fingertips (HP:0001211)3.35553041
37Recurrent cutaneous fungal infections (HP:0011370)3.33863631
38Chronic mucocutaneous candidiasis (HP:0002728)3.33863631
39Chronic diarrhea (HP:0002028)3.23559082
40Myositis (HP:0100614)3.21418530
41Autoimmune hemolytic anemia (HP:0001890)3.17624637
42Thrombocytosis (HP:0001894)3.13145522
43Hypoproteinemia (HP:0003075)3.03426596
44Gastrointestinal infarctions (HP:0005244)2.98868445
45Autoimmune thrombocytopenia (HP:0001973)2.97372113
46Lymphoma (HP:0002665)2.93168049
47IgA deficiency (HP:0002720)2.88065618
48Hypochromic microcytic anemia (HP:0004840)2.85234870
49Keratoconjunctivitis sicca (HP:0001097)2.73424623
50Thyroiditis (HP:0100646)2.68896963
51Bronchitis (HP:0012387)2.67921818
52Recurrent gram-negative bacterial infections (HP:0005420)2.64235113
53Agammaglobulinemia (HP:0004432)2.59747423
54Keratoconjunctivitis (HP:0001096)2.54052930
55Absent rod-and cone-mediated responses on ERG (HP:0007688)2.53614140
56Hypergammaglobulinemia (HP:0010702)2.49309384
57Cerebral palsy (HP:0100021)2.46581385
583-Methylglutaconic aciduria (HP:0003535)2.45262292
59Hemoptysis (HP:0002105)2.43221099
60Spontaneous hematomas (HP:0007420)2.40979783
61Congenital stationary night blindness (HP:0007642)2.40489402
62Amaurosis fugax (HP:0100576)2.40137843
63Encephalitis (HP:0002383)2.39352303
64Recurrent sinusitis (HP:0011108)2.35321711
65Mediastinal lymphadenopathy (HP:0100721)2.31932011
66Broad face (HP:0000283)2.30216688
67Vasculitis (HP:0002633)2.29713153
68Hypoplasia of the thymus (HP:0000778)2.28851691
69Meningitis (HP:0001287)2.28116011
70Increased IgE level (HP:0003212)2.26601220
71Chest pain (HP:0100749)2.25568251
72Loss of speech (HP:0002371)2.24518041
73Recurrent otitis media (HP:0000403)2.22775963
74Increased density of long bones (HP:0006392)2.22000085
75Tetany (HP:0001281)2.20930181
76Pulmonary infiltrates (HP:0002113)2.19210645
77Ureteral stenosis (HP:0000071)2.17249929
78Obstructive lung disease (HP:0006536)2.13102414
79Chronic obstructive pulmonary disease (HP:0006510)2.13102414
80Gingivitis (HP:0000230)2.12932371
81Gastrointestinal inflammation (HP:0004386)2.10382227
82Cheilitis (HP:0100825)2.08554446
83Inflammation of the large intestine (HP:0002037)2.08310344
84Chronic sinusitis (HP:0011109)2.07647833
85Hemiplegia (HP:0002301)2.07489266
86Anorexia (HP:0002039)2.07160355
87Retrobulbar optic neuritis (HP:0100654)2.06078862
88Optic neuritis (HP:0100653)2.06078862
89Oral leukoplakia (HP:0002745)2.05618989
90Gangrene (HP:0100758)2.03603648
91Abnormal platelet volume (HP:0011876)2.03181904
92Cellular immunodeficiency (HP:0005374)2.03163181
93Multiple enchondromatosis (HP:0005701)2.03026281
94Increased CSF protein (HP:0002922)2.00046953
95Papilloma (HP:0012740)1.99851059
96Verrucae (HP:0200043)1.99851059
97Hyperlipoproteinemia (HP:0010980)1.98930815
98Hypochromic anemia (HP:0001931)1.98191350
99Aplasia/Hypoplasia of the thymus (HP:0010515)1.97217582
100Reticulocytopenia (HP:0001896)1.94526674
101Bronchiectasis (HP:0002110)1.93854923
102Ureteral obstruction (HP:0006000)1.93379341
103Trigonocephaly (HP:0000243)1.93329168
104Poikiloderma (HP:0001029)1.92565700
105Posterior subcapsular cataract (HP:0007787)1.91309573
106Petechiae (HP:0000967)1.91153920
107Arterial thrombosis (HP:0004420)1.88727028
108Dislocated radial head (HP:0003083)1.88072887
109Abnormality of the prostate (HP:0008775)1.88047889
110Colitis (HP:0002583)1.88023614
111Abnormality of cells of the erythroid lineage (HP:0012130)1.87912183
112Epistaxis (HP:0000421)1.87356665
113Colon cancer (HP:0003003)1.85395787
114Seborrheic dermatitis (HP:0001051)1.83744427
115Amyotrophic lateral sclerosis (HP:0007354)1.83118461
116Spinal canal stenosis (HP:0003416)1.82768686
117Long clavicles (HP:0000890)1.81737249
118Acne (HP:0001061)1.81520697
119Abnormal rod and cone electroretinograms (HP:0008323)1.81408132
120Keratitis (HP:0000491)1.80246155
121Abnormality of oral frenula (HP:0000190)1.78123339
122Orchitis (HP:0100796)1.77632833
123Microcytic anemia (HP:0001935)1.75785133
124J-shaped sella turcica (HP:0002680)1.75316151
125Recurrent abscess formation (HP:0002722)1.75129254
126Abnormality of the radial head (HP:0003995)1.74526963
127Recurrent skin infections (HP:0001581)1.73958991
128Sepsis (HP:0100806)1.73691053
129Pulmonary embolism (HP:0002204)1.70254407
130Persistence of primary teeth (HP:0006335)1.69574790
131Hepatitis (HP:0012115)1.68518168
132Premature graying of hair (HP:0002216)1.68221281
133Bicuspid aortic valve (HP:0001647)1.68044534
134Abnormal number of erythroid precursors (HP:0012131)1.66284546
135Increased mean platelet volume (HP:0011877)1.65253807
136Pancytopenia (HP:0001876)1.64613419

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.94912147
2MAP4K16.10865309
3ITK3.54896981
4ZAP703.51101482
5SCYL23.50245726
6STK103.14090784
7JAK33.13364384
8FGFR42.75736705
9GRK72.61559018
10TAOK32.33759695
11RIPK42.29386152
12TYK22.25686422
13IKBKE2.18968255
14GRK62.14370570
15TAF12.05290664
16NLK2.00598052
17LCK1.95190881
18MST41.72935240
19TESK21.71676743
20TEC1.71465623
21FGFR31.66595923
22ERN11.63897258
23CSK1.63555449
24MAP3K141.57373338
25NME21.53803373
26EEF2K1.52560586
27JAK11.48677546
28CAMKK21.47620967
29MAP3K121.47463837
30RPS6KA41.31242438
31CDK121.29715818
32MOS1.27974216
33MARK31.27060601
34HCK1.26577298
35SYK1.24026270
36PRKCQ1.21821380
37TAOK11.21031795
38CAMKK11.20628544
39LRRK21.19849479
40MAP3K101.17801924
41NEK61.14935995
42IKBKB1.14425114
43BTK1.13614468
44PKN21.10994170
45KDR1.10158005
46PRKCH1.07720565
47PIM11.04033410
48TYRO31.03428148
49PASK1.03099709
50MAP3K131.02763445
51EIF2AK30.99561340
52TBK10.98886480
53WNK40.96898739
54GRK50.96127596
55BLK0.92844987
56CHUK0.90402364
57FGR0.89796323
58RPS6KB20.88033864
59ALK0.76416462
60MAP3K70.72664282
61JAK20.71524853
62TRPM70.70859206
63TLK10.70720639
64MELK0.68210656
65CDK40.67426983
66CDC70.67379749
67FGFR10.66369095
68CLK10.64853550
69FES0.64746983
70LIMK10.63799522
71LYN0.63215406
72MAP3K80.62736426
73MAP2K30.62716302
74TRIB30.59110997
75SIK20.57637193
76NTRK20.56969563
77KIT0.55522791
78RPS6KA50.54646845
79BRD40.54490257
80STK40.54452838
81MARK20.54006196
82TGFBR10.53250666
83IRAK40.52797608
84PDGFRB0.51939095
85PTK60.51754916
86GRK10.51376096
87NEK20.49453757
88MAPK70.49439070
89BUB10.49400909
90INSR0.47317052
91ADRBK20.46588394
92TNK20.46425534
93ACVR1B0.44682935
94MAP3K110.42414738
95PRPF4B0.41544564
96SRPK10.40309860
97TSSK60.39878919
98ROCK20.39750299
99PDK10.39529466
100TTN0.39478970
101MAP2K60.38952588
102CSF1R0.37385951
103EPHB10.37108759
104HIPK20.36776020
105TGFBR20.36736261
106MAPKAPK20.36624229
107EPHA30.36046872
108ILK0.35912243
109CHEK10.34994705
110ERBB30.34489960
111FLT30.34281839
112FYN0.34122546
113MAP2K20.33561133
114MYLK0.33319893
115MAP3K30.32880578
116TAOK20.31954374
117PLK40.30255381
118IGF1R0.29335091
119SIK30.29174277
120PIK3CG0.28298968
121ATR0.27339503
122CDK60.27074747
123PIM20.25821003
124PTK2B0.24979009
125PRKD20.24612644
126MAPK110.22234936
127ROCK10.21870844
128DAPK10.21840703
129RPS6KA60.21761683
130STK390.21623512
131ADRBK10.21260653
132MAPK150.21013045
133STK110.20165638
134CSNK2A20.19588742
135TESK10.19536603
136MAPK30.19148525
137RAF10.18555005
138EGFR0.18447770
139CDK20.18423480

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.84185258
2T cell receptor signaling pathway_Homo sapiens_hsa046604.37289677
3Graft-versus-host disease_Homo sapiens_hsa053322.75677849
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.74254837
5Measles_Homo sapiens_hsa051622.69920195
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.69587243
7Allograft rejection_Homo sapiens_hsa053302.67823790
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.51388972
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.49515785
10Ribosome_Homo sapiens_hsa030102.37240291
11Antigen processing and presentation_Homo sapiens_hsa046122.32572751
12Autoimmune thyroid disease_Homo sapiens_hsa053202.13303494
13Hematopoietic cell lineage_Homo sapiens_hsa046401.99008901
14Viral myocarditis_Homo sapiens_hsa054161.87276450
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.72961242
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.68307393
17Leishmaniasis_Homo sapiens_hsa051401.63264896
18Spliceosome_Homo sapiens_hsa030401.62049339
19Herpes simplex infection_Homo sapiens_hsa051681.60475610
20Osteoclast differentiation_Homo sapiens_hsa043801.50603905
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.50237166
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.49658218
23DNA replication_Homo sapiens_hsa030301.46345711
24Type I diabetes mellitus_Homo sapiens_hsa049401.39325411
25Mismatch repair_Homo sapiens_hsa034301.38631529
26Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.37716387
27HTLV-I infection_Homo sapiens_hsa051661.28514379
28Acute myeloid leukemia_Homo sapiens_hsa052211.26941326
29Shigellosis_Homo sapiens_hsa051311.23398810
30B cell receptor signaling pathway_Homo sapiens_hsa046621.23107320
31Hepatitis B_Homo sapiens_hsa051611.20919751
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.19252920
33Leukocyte transendothelial migration_Homo sapiens_hsa046701.19132568
34Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.17402344
35Epstein-Barr virus infection_Homo sapiens_hsa051691.17166249
36RNA transport_Homo sapiens_hsa030131.16485922
37NOD-like receptor signaling pathway_Homo sapiens_hsa046211.13320800
38Toxoplasmosis_Homo sapiens_hsa051451.08993568
39Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.08895643
40Chemokine signaling pathway_Homo sapiens_hsa040621.07623392
41Asthma_Homo sapiens_hsa053101.03200111
42Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02255468
43Regulation of autophagy_Homo sapiens_hsa041400.99276318
44Colorectal cancer_Homo sapiens_hsa052100.98936148
45One carbon pool by folate_Homo sapiens_hsa006700.98673619
46Non-homologous end-joining_Homo sapiens_hsa034500.93784164
47Viral carcinogenesis_Homo sapiens_hsa052030.93261417
48Base excision repair_Homo sapiens_hsa034100.92368943
49Influenza A_Homo sapiens_hsa051640.92031951
50Apoptosis_Homo sapiens_hsa042100.91041823
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.90972883
52RNA polymerase_Homo sapiens_hsa030200.84245885
53RNA degradation_Homo sapiens_hsa030180.83850280
54Pancreatic cancer_Homo sapiens_hsa052120.83720413
55TNF signaling pathway_Homo sapiens_hsa046680.83693053
56Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.83155014
57p53 signaling pathway_Homo sapiens_hsa041150.82974611
58mRNA surveillance pathway_Homo sapiens_hsa030150.81210053
59Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.81187204
60Legionellosis_Homo sapiens_hsa051340.79026106
61African trypanosomiasis_Homo sapiens_hsa051430.79005487
62Chronic myeloid leukemia_Homo sapiens_hsa052200.78568655
63Proteasome_Homo sapiens_hsa030500.77092530
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74388033
65Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.71531128
66Nucleotide excision repair_Homo sapiens_hsa034200.71450710
67Hepatitis C_Homo sapiens_hsa051600.70406756
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.66511057
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.65848575
70Prolactin signaling pathway_Homo sapiens_hsa049170.65784887
71Renin secretion_Homo sapiens_hsa049240.65627738
72Toll-like receptor signaling pathway_Homo sapiens_hsa046200.64634557
73AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64354380
74Platelet activation_Homo sapiens_hsa046110.59586161
75VEGF signaling pathway_Homo sapiens_hsa043700.58927913
76Thyroid cancer_Homo sapiens_hsa052160.56026970
77Cell cycle_Homo sapiens_hsa041100.55435677
78Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54464571
79Small cell lung cancer_Homo sapiens_hsa052220.52901786
80Tuberculosis_Homo sapiens_hsa051520.50684422
81Homologous recombination_Homo sapiens_hsa034400.50601735
82Notch signaling pathway_Homo sapiens_hsa043300.50577821
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.49375880
84Salmonella infection_Homo sapiens_hsa051320.48075781
85Staphylococcus aureus infection_Homo sapiens_hsa051500.47572322
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46892904
87Cyanoamino acid metabolism_Homo sapiens_hsa004600.46882229
88Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46515288
89Pyrimidine metabolism_Homo sapiens_hsa002400.45824064
90Phototransduction_Homo sapiens_hsa047440.45328578
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44716502
92Malaria_Homo sapiens_hsa051440.44484745
93mTOR signaling pathway_Homo sapiens_hsa041500.43274803
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42499720
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41159256
96Pertussis_Homo sapiens_hsa051330.40899096
97Endocytosis_Homo sapiens_hsa041440.37034127
98Fanconi anemia pathway_Homo sapiens_hsa034600.35868855
99Non-small cell lung cancer_Homo sapiens_hsa052230.35800199
100Prostate cancer_Homo sapiens_hsa052150.34597988
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.34522368
102MAPK signaling pathway_Homo sapiens_hsa040100.33751821
103Caffeine metabolism_Homo sapiens_hsa002320.33685619
104Rap1 signaling pathway_Homo sapiens_hsa040150.33347425
105Basal transcription factors_Homo sapiens_hsa030220.33254155
106Renal cell carcinoma_Homo sapiens_hsa052110.32905011
107Drug metabolism - other enzymes_Homo sapiens_hsa009830.32337321
108Parkinsons disease_Homo sapiens_hsa050120.31794968
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.29852086
110Rheumatoid arthritis_Homo sapiens_hsa053230.29539770
111FoxO signaling pathway_Homo sapiens_hsa040680.29068733
112Oxidative phosphorylation_Homo sapiens_hsa001900.28090501
113MicroRNAs in cancer_Homo sapiens_hsa052060.26558658
114Glycosaminoglycan degradation_Homo sapiens_hsa005310.24679449
115Pathways in cancer_Homo sapiens_hsa052000.24439133
116Linoleic acid metabolism_Homo sapiens_hsa005910.23934622
117Olfactory transduction_Homo sapiens_hsa047400.23019989
118Endometrial cancer_Homo sapiens_hsa052130.22985353
119Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.20898725
120ABC transporters_Homo sapiens_hsa020100.19622965
121Ras signaling pathway_Homo sapiens_hsa040140.18999624
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.18861071
123Morphine addiction_Homo sapiens_hsa050320.18768014
124Adipocytokine signaling pathway_Homo sapiens_hsa049200.18570667
125Alzheimers disease_Homo sapiens_hsa050100.18415594
126Calcium signaling pathway_Homo sapiens_hsa040200.13890797
127Phagosome_Homo sapiens_hsa041450.12961977
128Carbohydrate digestion and absorption_Homo sapiens_hsa049730.11068370
129Mineral absorption_Homo sapiens_hsa049780.10856416
130Nitrogen metabolism_Homo sapiens_hsa009100.10725181
131Long-term potentiation_Homo sapiens_hsa047200.10568829
132Folate biosynthesis_Homo sapiens_hsa007900.10411513
133Retinol metabolism_Homo sapiens_hsa008300.09677461

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