

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 9.09528878 |
| 2 | positive regulation of interleukin-17 production (GO:0032740) | 8.57013857 |
| 3 | regulation of natural killer cell differentiation (GO:0032823) | 8.07486234 |
| 4 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 7.64712636 |
| 5 | negative regulation of T cell differentiation in thymus (GO:0033085) | 7.59083933 |
| 6 | cellular response to interleukin-15 (GO:0071350) | 7.42845558 |
| 7 | response to interleukin-15 (GO:0070672) | 7.14543763 |
| 8 | response to xenobiotic stimulus (GO:0009410) | 7.14064227 |
| 9 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 7.02521322 |
| 10 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 6.55959945 |
| 11 | regulation of isotype switching to IgG isotypes (GO:0048302) | 6.43937036 |
| 12 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 6.43158599 |
| 13 | negative regulation of cell killing (GO:0031342) | 6.38232250 |
| 14 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.38232250 |
| 15 | positive regulation of T cell differentiation in thymus (GO:0033089) | 6.35710003 |
| 16 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 6.32113822 |
| 17 | cysteine metabolic process (GO:0006534) | 6.27606230 |
| 18 | regulation of gamma-delta T cell differentiation (GO:0045586) | 6.22460277 |
| 19 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 5.97695128 |
| 20 | response to nitrosative stress (GO:0051409) | 5.88383341 |
| 21 | viral mRNA export from host cell nucleus (GO:0046784) | 5.80020521 |
| 22 | positive regulation of natural killer cell activation (GO:0032816) | 5.73614023 |
| 23 | regulation of T cell differentiation in thymus (GO:0033081) | 5.67881223 |
| 24 | positive regulation of T cell apoptotic process (GO:0070234) | 5.64791970 |
| 25 | regulation of chronic inflammatory response (GO:0002676) | 5.55114178 |
| 26 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 5.52145760 |
| 27 | regulation of natural killer cell mediated immunity (GO:0002715) | 5.52145760 |
| 28 | negative regulation of B cell mediated immunity (GO:0002713) | 5.50461873 |
| 29 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 5.50461873 |
| 30 | positive regulation of interleukin-10 production (GO:0032733) | 5.40388201 |
| 31 | regulation of gamma-delta T cell activation (GO:0046643) | 5.33690918 |
| 32 | regulation of interleukin-17 production (GO:0032660) | 5.17019847 |
| 33 | negative regulation of adaptive immune response (GO:0002820) | 5.12407761 |
| 34 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.11998793 |
| 35 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 5.09563247 |
| 36 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.89950594 |
| 37 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.85044729 |
| 38 | regulation of thymocyte apoptotic process (GO:0070243) | 4.77152756 |
| 39 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.76804483 |
| 40 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.76563125 |
| 41 | negative regulation of T cell mediated immunity (GO:0002710) | 4.70132550 |
| 42 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.67030692 |
| 43 | regulation of isotype switching (GO:0045191) | 4.63148383 |
| 44 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.60456377 |
| 45 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.60456377 |
| 46 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.58775899 |
| 47 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.37844002 |
| 48 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.30146840 |
| 49 | T cell lineage commitment (GO:0002360) | 4.23609617 |
| 50 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 4.22644166 |
| 51 | production of molecular mediator of immune response (GO:0002440) | 4.21871417 |
| 52 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.19490996 |
| 53 | regulation of natural killer cell activation (GO:0032814) | 4.16947089 |
| 54 | regulation of immunoglobulin production (GO:0002637) | 4.16737697 |
| 55 | regulation of cell killing (GO:0031341) | 4.15371841 |
| 56 | negative regulation of T cell differentiation (GO:0045581) | 4.14895429 |
| 57 | positive regulation of B cell proliferation (GO:0030890) | 4.12264816 |
| 58 | positive regulation of isotype switching (GO:0045830) | 4.07403433 |
| 59 | positive regulation of cell killing (GO:0031343) | 4.01661819 |
| 60 | L-ascorbic acid metabolic process (GO:0019852) | 3.99394863 |
| 61 | positive regulation of tyrosine phosphorylation of Stat3 protein (GO:0042517) | 3.95545821 |
| 62 | regulation of chemokine biosynthetic process (GO:0045073) | 3.91070977 |
| 63 | regulation of interleukin-10 production (GO:0032653) | 3.90580320 |
| 64 | S-adenosylmethionine metabolic process (GO:0046500) | 3.88401557 |
| 65 | regulation of mitochondrial depolarization (GO:0051900) | 3.85384021 |
| 66 | positive regulation of cytokine biosynthetic process (GO:0042108) | 3.77708785 |
| 67 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.74500123 |
| 68 | Peyers patch development (GO:0048541) | 3.70657523 |
| 69 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.70657523 |
| 70 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.68643627 |
| 71 | defense response to protozoan (GO:0042832) | 3.62765394 |
| 72 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.62209651 |
| 73 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.55468781 |
| 74 | regulation of lymphocyte mediated immunity (GO:0002706) | 3.54469105 |
| 75 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.48562420 |
| 76 | positive regulation of DNA recombination (GO:0045911) | 3.45197087 |
| 77 | positive regulation of lymphocyte differentiation (GO:0045621) | 3.39654854 |
| 78 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.33801060 |
| 79 | tolerance induction (GO:0002507) | 3.33788960 |
| 80 | positive regulation of B cell activation (GO:0050871) | 3.33047870 |
| 81 | negative regulation of lymphocyte differentiation (GO:0045620) | 3.27356065 |
| 82 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.26489344 |
| 83 | positive regulation of production of molecular mediator of immune response (GO:0002702) | 3.22827822 |
| 84 | positive regulation of immunoglobulin production (GO:0002639) | 3.22365349 |
| 85 | regulation of tyrosine phosphorylation of Stat3 protein (GO:0042516) | 3.22098139 |
| 86 | natural killer cell differentiation (GO:0001779) | 3.20377165 |
| 87 | cytokine production involved in immune response (GO:0002367) | 3.20294240 |
| 88 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 3.18654087 |
| 89 | regulation of B cell mediated immunity (GO:0002712) | 3.18469331 |
| 90 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 3.18153928 |
| 91 | glutathione biosynthetic process (GO:0006750) | 3.17399705 |
| 92 | regulation of production of molecular mediator of immune response (GO:0002700) | 3.17200740 |
| 93 | response to protozoan (GO:0001562) | 3.16943779 |
| 94 | regulation of B cell activation (GO:0050864) | 3.15257018 |
| 95 | positive regulation of leukocyte mediated immunity (GO:0002705) | 3.12178801 |
| 96 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 3.09298265 |
| 97 | positive regulation of cytokine production involved in immune response (GO:0002720) | 3.08850397 |
| 98 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.08358820 |
| 99 | positive regulation of tissue remodeling (GO:0034105) | 3.02448600 |
| 100 | positive regulation of natural killer cell differentiation (GO:0032825) | 11.6369929 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 7.02662189 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.02678956 |
| 3 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 5.19364067 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.14615243 |
| 5 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 5.00135875 |
| 6 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.79101119 |
| 7 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.56873592 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.52289376 |
| 9 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.51198375 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 3.07529307 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.95333725 |
| 12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.80940762 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.76720737 |
| 14 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.68116844 |
| 15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.66300478 |
| 16 | MYC_22102868_ChIP-Seq_BL_Human | 2.57485464 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.52813001 |
| 18 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.43607139 |
| 19 | MAF_26560356_Chip-Seq_TH1_Human | 2.42711888 |
| 20 | MYB_26560356_Chip-Seq_TH1_Human | 2.42672667 |
| 21 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.39925873 |
| 22 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.05343096 |
| 23 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 2.02796317 |
| 24 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.95103432 |
| 25 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.91525742 |
| 26 | GATA3_26560356_Chip-Seq_TH2_Human | 1.90142510 |
| 27 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.87100408 |
| 28 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.84549257 |
| 29 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.72940562 |
| 30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.61085407 |
| 31 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.60991239 |
| 32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58330120 |
| 33 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.55932722 |
| 34 | MAF_26560356_Chip-Seq_TH2_Human | 1.54391969 |
| 35 | UTX_26944678_Chip-Seq_JUKART_Human | 1.53802481 |
| 36 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.53791142 |
| 37 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.52738539 |
| 38 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.49042097 |
| 39 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.45299059 |
| 40 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.44720427 |
| 41 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.42950500 |
| 42 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.42266208 |
| 43 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.37358966 |
| 44 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.28434341 |
| 45 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.28013538 |
| 46 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.26140322 |
| 47 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.25958857 |
| 48 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25414154 |
| 49 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.20921582 |
| 50 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18709358 |
| 51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.18652191 |
| 52 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.17191802 |
| 53 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.16206898 |
| 54 | VDR_22108803_ChIP-Seq_LS180_Human | 1.14077606 |
| 55 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.09821329 |
| 56 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.07949288 |
| 57 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.06814441 |
| 58 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.06699599 |
| 59 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06622960 |
| 60 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.02402610 |
| 61 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98349148 |
| 62 | GATA1_22025678_ChIP-Seq_K562_Human | 0.98018686 |
| 63 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97241884 |
| 64 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.96872274 |
| 65 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.96102283 |
| 66 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92713396 |
| 67 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.92217880 |
| 68 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92146259 |
| 69 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91701377 |
| 70 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88986348 |
| 71 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.88103226 |
| 72 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.87563589 |
| 73 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.87084262 |
| 74 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.83814565 |
| 75 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.83414066 |
| 76 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83041014 |
| 77 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.81508003 |
| 78 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.81223394 |
| 79 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.80816000 |
| 80 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.79748375 |
| 81 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.79625138 |
| 82 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.78632641 |
| 83 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.78631320 |
| 84 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.77930271 |
| 85 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.77919898 |
| 86 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.77252542 |
| 87 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.76900463 |
| 88 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.75455018 |
| 89 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.75396072 |
| 90 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.73744125 |
| 91 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.73121293 |
| 92 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.72671993 |
| 93 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.72321081 |
| 94 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.72079026 |
| 95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.71727926 |
| 96 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.69675310 |
| 97 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.69269431 |
| 98 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.69071499 |
| 99 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.67152691 |
| 100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.65920633 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001348_abnormal_lacrimal_gland | 5.29087379 |
| 2 | MP0001873_stomach_inflammation | 4.47609056 |
| 3 | MP0003763_abnormal_thymus_physiology | 4.12341704 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.96010322 |
| 5 | MP0006082_CNS_inflammation | 3.56210274 |
| 6 | MP0003436_decreased_susceptibility_to | 3.38070518 |
| 7 | MP0004742_abnormal_vestibular_system | 3.26919330 |
| 8 | MP0000685_abnormal_immune_system | 3.26134429 |
| 9 | MP0005387_immune_system_phenotype | 3.17385768 |
| 10 | MP0001790_abnormal_immune_system | 3.17385768 |
| 11 | MP0005671_abnormal_response_to | 3.02672027 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.94853698 |
| 13 | MP0001800_abnormal_humoral_immune | 2.73698859 |
| 14 | MP0003890_abnormal_embryonic-extraembry | 2.58465210 |
| 15 | MP0008057_abnormal_DNA_replication | 2.47127627 |
| 16 | MP0000750_abnormal_muscle_regeneration | 2.41381105 |
| 17 | MP0005423_abnormal_somatic_nervous | 2.31767489 |
| 18 | MP0002723_abnormal_immune_serum | 2.25799397 |
| 19 | MP0005310_abnormal_salivary_gland | 2.24233258 |
| 20 | MP0001986_abnormal_taste_sensitivity | 2.21529811 |
| 21 | MP0002405_respiratory_system_inflammati | 2.18661645 |
| 22 | MP0002138_abnormal_hepatobiliary_system | 2.17390331 |
| 23 | MP0002420_abnormal_adaptive_immunity | 2.16333918 |
| 24 | MP0002452_abnormal_antigen_presenting | 2.12836388 |
| 25 | MP0009785_altered_susceptibility_to | 2.09365812 |
| 26 | MP0010155_abnormal_intestine_physiology | 2.03815256 |
| 27 | MP0001819_abnormal_immune_cell | 2.00925289 |
| 28 | MP0000569_abnormal_digit_pigmentation | 1.98166821 |
| 29 | MP0005025_abnormal_response_to | 1.97263625 |
| 30 | MP0003724_increased_susceptibility_to | 1.89800943 |
| 31 | MP0003646_muscle_fatigue | 1.89481157 |
| 32 | MP0002254_reproductive_system_inflammat | 1.88206267 |
| 33 | MP0004381_abnormal_hair_follicle | 1.81075233 |
| 34 | MP0002398_abnormal_bone_marrow | 1.78102590 |
| 35 | MP0000716_abnormal_immune_system | 1.67468955 |
| 36 | MP0003806_abnormal_nucleotide_metabolis | 1.61925770 |
| 37 | MP0000689_abnormal_spleen_morphology | 1.59132025 |
| 38 | MP0009333_abnormal_splenocyte_physiolog | 1.57096258 |
| 39 | MP0004134_abnormal_chest_morphology | 1.54738195 |
| 40 | MP0000703_abnormal_thymus_morphology | 1.53645495 |
| 41 | MP0003943_abnormal_hepatobiliary_system | 1.49469728 |
| 42 | MP0002419_abnormal_innate_immunity | 1.49299776 |
| 43 | MP0002132_abnormal_respiratory_system | 1.49243229 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.42884974 |
| 45 | MP0008872_abnormal_physiological_respon | 1.36720010 |
| 46 | MP0003866_abnormal_defecation | 1.31845349 |
| 47 | MP0002722_abnormal_immune_system | 1.31672967 |
| 48 | MP0004808_abnormal_hematopoietic_stem | 1.30702073 |
| 49 | MP0002429_abnormal_blood_cell | 1.22684459 |
| 50 | MP0010368_abnormal_lymphatic_system | 1.18805690 |
| 51 | MP0001968_abnormal_touch/_nociception | 1.17675534 |
| 52 | MP0003045_fibrosis | 1.13092051 |
| 53 | MP0002148_abnormal_hypersensitivity_rea | 1.10771154 |
| 54 | MP0008469_abnormal_protein_level | 1.08602105 |
| 55 | MP0001533_abnormal_skeleton_physiology | 1.08484060 |
| 56 | MP0002102_abnormal_ear_morphology | 1.00358387 |
| 57 | MP0003221_abnormal_cardiomyocyte_apopto | 0.99925285 |
| 58 | MP0004142_abnormal_muscle_tone | 0.98978597 |
| 59 | MP0002269_muscular_atrophy | 0.98950616 |
| 60 | MP0004947_skin_inflammation | 0.97358980 |
| 61 | MP0001243_abnormal_dermal_layer | 0.93497546 |
| 62 | MP0001663_abnormal_digestive_system | 0.92697991 |
| 63 | MP0009840_abnormal_foam_cell | 0.92320268 |
| 64 | MP0001851_eye_inflammation | 0.92227464 |
| 65 | MP0005408_hypopigmentation | 0.87909924 |
| 66 | MP0004145_abnormal_muscle_electrophysio | 0.87203571 |
| 67 | MP0009764_decreased_sensitivity_to | 0.87084432 |
| 68 | MP0000465_gastrointestinal_hemorrhage | 0.86802424 |
| 69 | MP0002693_abnormal_pancreas_physiology | 0.85178518 |
| 70 | MP0008875_abnormal_xenobiotic_pharmacok | 0.79051877 |
| 71 | MP0005075_abnormal_melanosome_morpholog | 0.77549570 |
| 72 | MP0002163_abnormal_gland_morphology | 0.75952405 |
| 73 | MP0001501_abnormal_sleep_pattern | 0.75485825 |
| 74 | MP0005166_decreased_susceptibility_to | 0.75269990 |
| 75 | MP0002736_abnormal_nociception_after | 0.74196033 |
| 76 | MP0000015_abnormal_ear_pigmentation | 0.70062155 |
| 77 | MP0002106_abnormal_muscle_physiology | 0.68519894 |
| 78 | MP0003329_amyloid_beta_deposits | 0.67465428 |
| 79 | MP0005647_abnormal_sex_gland | 0.64666306 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.64014088 |
| 81 | MP0003795_abnormal_bone_structure | 0.63061817 |
| 82 | MP0000604_amyloidosis | 0.62318849 |
| 83 | MP0001958_emphysema | 0.61319150 |
| 84 | MP0003633_abnormal_nervous_system | 0.61291623 |
| 85 | MP0005390_skeleton_phenotype | 0.59910784 |
| 86 | MP0003303_peritoneal_inflammation | 0.57558308 |
| 87 | MP0008961_abnormal_basal_metabolism | 0.51250257 |
| 88 | MP0000470_abnormal_stomach_morphology | 0.50322420 |
| 89 | MP0003300_gastrointestinal_ulcer | 0.49467885 |
| 90 | MP0002166_altered_tumor_susceptibility | 0.49316679 |
| 91 | MP0005381_digestive/alimentary_phenotyp | 0.47165435 |
| 92 | MP0002933_joint_inflammation | 0.44642801 |
| 93 | MP0002229_neurodegeneration | 0.43076331 |
| 94 | MP0000858_altered_metastatic_potential | 0.42156046 |
| 95 | MP0003186_abnormal_redox_activity | 0.41823100 |
| 96 | MP0005369_muscle_phenotype | 0.41499139 |
| 97 | MP0001881_abnormal_mammary_gland | 0.40268704 |
| 98 | MP0002998_abnormal_bone_remodeling | 0.40177077 |
| 99 | MP0009745_abnormal_behavioral_response | 0.40084719 |
| 100 | MP0000313_abnormal_cell_death | 0.39570467 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chronic diarrhea (HP:0002028) | 9.41310418 |
| 2 | Stomatitis (HP:0010280) | 7.17246534 |
| 3 | Severe combined immunodeficiency (HP:0004430) | 6.65373804 |
| 4 | T lymphocytopenia (HP:0005403) | 6.61283430 |
| 5 | Abnormality of T cell number (HP:0011839) | 5.99143908 |
| 6 | Inflammation of the large intestine (HP:0002037) | 5.58451287 |
| 7 | Thyroiditis (HP:0100646) | 5.54910218 |
| 8 | Combined immunodeficiency (HP:0005387) | 5.33198862 |
| 9 | Gastrointestinal inflammation (HP:0004386) | 5.25363659 |
| 10 | Increased IgM level (HP:0003496) | 4.75645589 |
| 11 | Abnormality of T cells (HP:0002843) | 4.70007294 |
| 12 | Abnormality of eosinophils (HP:0001879) | 4.30648625 |
| 13 | Acute myeloid leukemia (HP:0004808) | 3.98815613 |
| 14 | Nasal polyposis (HP:0100582) | 3.86535044 |
| 15 | Amyotrophic lateral sclerosis (HP:0007354) | 3.79010120 |
| 16 | Abnormality of incisor morphology (HP:0011063) | 3.74748929 |
| 17 | IgG deficiency (HP:0004315) | 3.59192936 |
| 18 | Recurrent bronchitis (HP:0002837) | 3.52783840 |
| 19 | Chronic otitis media (HP:0000389) | 3.46104002 |
| 20 | Bilateral sensorineural hearing impairment (HP:0008619) | 3.45746353 |
| 21 | Leukocytosis (HP:0001974) | 3.40425259 |
| 22 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.37811389 |
| 23 | Curly hair (HP:0002212) | 3.35398614 |
| 24 | Abnormality of the nasal mucosa (HP:0000433) | 3.33524752 |
| 25 | Recurrent fungal infections (HP:0002841) | 3.26270902 |
| 26 | Recurrent bacterial skin infections (HP:0005406) | 3.21913955 |
| 27 | Recurrent cutaneous fungal infections (HP:0011370) | 3.20244887 |
| 28 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.20244887 |
| 29 | Megalencephaly (HP:0001355) | 3.13009136 |
| 30 | Recurrent skin infections (HP:0001581) | 3.11250783 |
| 31 | Abnormality of T cell physiology (HP:0011840) | 3.09616478 |
| 32 | Entropion (HP:0000621) | 3.06010647 |
| 33 | Abnormality of DNA repair (HP:0003254) | 2.98210433 |
| 34 | Cutaneous melanoma (HP:0012056) | 2.96570004 |
| 35 | IgA deficiency (HP:0002720) | 2.86231762 |
| 36 | Mediastinal lymphadenopathy (HP:0100721) | 2.86226525 |
| 37 | Pustule (HP:0200039) | 2.83888969 |
| 38 | Recurrent abscess formation (HP:0002722) | 2.79674920 |
| 39 | B lymphocytopenia (HP:0010976) | 2.77956113 |
| 40 | Pulmonary infiltrates (HP:0002113) | 2.69428338 |
| 41 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.66631027 |
| 42 | Mutism (HP:0002300) | 2.65534817 |
| 43 | Gingivitis (HP:0000230) | 2.61111492 |
| 44 | Myositis (HP:0100614) | 2.59953444 |
| 45 | Fatigue (HP:0012378) | 2.57614904 |
| 46 | Bronchitis (HP:0012387) | 2.55587601 |
| 47 | Poikiloderma (HP:0001029) | 2.45280048 |
| 48 | Abnormality of B cell number (HP:0010975) | 2.44883363 |
| 49 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.42425587 |
| 50 | Eczematoid dermatitis (HP:0000976) | 2.41880380 |
| 51 | Melanoma (HP:0002861) | 2.36834358 |
| 52 | Gastrointestinal infarctions (HP:0005244) | 2.34191944 |
| 53 | Polyneuropathy (HP:0001271) | 2.32933082 |
| 54 | Basal cell carcinoma (HP:0002671) | 2.27840331 |
| 55 | Keratoconjunctivitis (HP:0001096) | 2.27311425 |
| 56 | Lymphoma (HP:0002665) | 2.18977092 |
| 57 | Orchitis (HP:0100796) | 2.13445613 |
| 58 | Oral leukoplakia (HP:0002745) | 2.13043487 |
| 59 | Keratitis (HP:0000491) | 2.11417148 |
| 60 | Cystic hygroma (HP:0000476) | 2.09312149 |
| 61 | Aplastic anemia (HP:0001915) | 2.08183496 |
| 62 | Chronic sinusitis (HP:0011109) | 2.04648976 |
| 63 | Optic neuritis (HP:0100653) | 2.02024052 |
| 64 | Retrobulbar optic neuritis (HP:0100654) | 2.02024052 |
| 65 | Upper limb muscle weakness (HP:0003484) | 2.00699192 |
| 66 | Metaphyseal dysplasia (HP:0100255) | 1.97796612 |
| 67 | Abnormality of macrophages (HP:0004311) | 1.97393187 |
| 68 | Abnormality of the endocardium (HP:0004306) | 1.95887642 |
| 69 | Alveolar cell carcinoma (HP:0006519) | 1.95493624 |
| 70 | Chest pain (HP:0100749) | 1.93722451 |
| 71 | Hypergammaglobulinemia (HP:0010702) | 1.90065660 |
| 72 | Pruritus (HP:0000989) | 1.88230006 |
| 73 | Autoimmune hemolytic anemia (HP:0001890) | 1.85966903 |
| 74 | Type I diabetes mellitus (HP:0100651) | 1.85695709 |
| 75 | Hypoplasia of the thymus (HP:0000778) | 1.85388873 |
| 76 | Eosinophilia (HP:0001880) | 1.83864194 |
| 77 | Keratoconjunctivitis sicca (HP:0001097) | 1.83204595 |
| 78 | Agammaglobulinemia (HP:0004432) | 1.81614153 |
| 79 | Somatic mutation (HP:0001428) | 1.81166860 |
| 80 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.78522228 |
| 81 | Abnormality of the costochondral junction (HP:0000919) | 1.75571481 |
| 82 | Vasculitis (HP:0002633) | 1.75074427 |
| 83 | Neutropenia (HP:0001875) | 1.74010218 |
| 84 | Gingival bleeding (HP:0000225) | 1.71654976 |
| 85 | Chronic hepatic failure (HP:0100626) | 1.71390566 |
| 86 | Cubitus valgus (HP:0002967) | 1.70937405 |
| 87 | Hemoptysis (HP:0002105) | 1.70647853 |
| 88 | Hypobetalipoproteinemia (HP:0003563) | 1.70461346 |
| 89 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.70138537 |
| 90 | Retinal dysplasia (HP:0007973) | 1.68570269 |
| 91 | Recurrent viral infections (HP:0004429) | 1.66800394 |
| 92 | Muscle fibrillation (HP:0010546) | 1.65362230 |
| 93 | Polycythemia (HP:0001901) | 1.64335420 |
| 94 | Coarse hair (HP:0002208) | 1.63070731 |
| 95 | Deep philtrum (HP:0002002) | 1.63021898 |
| 96 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.62122325 |
| 97 | Meningitis (HP:0001287) | 1.61983758 |
| 98 | Tongue fasciculations (HP:0001308) | 1.61068069 |
| 99 | Cerebral hemorrhage (HP:0001342) | 1.60231822 |
| 100 | Arterial thrombosis (HP:0004420) | 1.58368151 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KSR2 | 4.55662758 |
| 2 | PAK6 | 3.70261857 |
| 3 | HIPK2 | 3.46648119 |
| 4 | KSR1 | 3.35693801 |
| 5 | MAP4K1 | 3.05924870 |
| 6 | RAF1 | 2.91843036 |
| 7 | DYRK2 | 2.88465439 |
| 8 | TXK | 2.80910663 |
| 9 | EIF2AK3 | 2.63249543 |
| 10 | TAOK3 | 2.58060103 |
| 11 | ITK | 2.46245014 |
| 12 | AKT3 | 2.37902338 |
| 13 | MAP3K12 | 2.30939535 |
| 14 | PAK3 | 2.30154086 |
| 15 | LATS1 | 2.27720023 |
| 16 | JAK1 | 2.23263443 |
| 17 | MST4 | 2.15084512 |
| 18 | TYK2 | 2.04127909 |
| 19 | JAK3 | 1.85967071 |
| 20 | IKBKB | 1.74858299 |
| 21 | TAOK1 | 1.71803815 |
| 22 | NLK | 1.63012511 |
| 23 | TAOK2 | 1.60122163 |
| 24 | NUAK1 | 1.59552475 |
| 25 | PRKAA2 | 1.59462615 |
| 26 | BRD4 | 1.57305533 |
| 27 | JAK2 | 1.54729054 |
| 28 | ZAP70 | 1.52286230 |
| 29 | RIPK4 | 1.52282031 |
| 30 | BTK | 1.47846654 |
| 31 | HCK | 1.40687353 |
| 32 | CLK1 | 1.36751400 |
| 33 | MAP2K3 | 1.33077414 |
| 34 | NME1 | 1.32255177 |
| 35 | CHUK | 1.26789198 |
| 36 | EIF2AK1 | 1.21034603 |
| 37 | TNK2 | 1.16471257 |
| 38 | FES | 1.15651038 |
| 39 | MAP3K11 | 1.13456555 |
| 40 | MAP3K14 | 1.09555656 |
| 41 | TEC | 1.08163128 |
| 42 | NEK6 | 1.08055099 |
| 43 | MAP3K3 | 1.07542917 |
| 44 | SIK3 | 1.02951914 |
| 45 | LCK | 0.99186443 |
| 46 | ADRBK2 | 0.96064314 |
| 47 | CDK4 | 0.91664026 |
| 48 | SGK223 | 0.90481185 |
| 49 | SGK494 | 0.90481185 |
| 50 | CSK | 0.86771933 |
| 51 | LYN | 0.85483072 |
| 52 | SGK2 | 0.85369811 |
| 53 | EIF2AK2 | 0.82722266 |
| 54 | TIE1 | 0.81758144 |
| 55 | SCYL2 | 0.81151134 |
| 56 | TGFBR2 | 0.80121882 |
| 57 | SYK | 0.74526961 |
| 58 | MAP3K13 | 0.72608376 |
| 59 | PTK6 | 0.72362218 |
| 60 | GRK7 | 0.70692994 |
| 61 | SGK1 | 0.66583533 |
| 62 | RPS6KA1 | 0.64808129 |
| 63 | ACVR1B | 0.61540147 |
| 64 | MAP2K1 | 0.58833490 |
| 65 | MARK3 | 0.58270628 |
| 66 | CDK12 | 0.57622612 |
| 67 | STK10 | 0.56470809 |
| 68 | CSNK1A1L | 0.54372874 |
| 69 | BMPR2 | 0.53991884 |
| 70 | CAMKK1 | 0.52376543 |
| 71 | IKBKE | 0.51478371 |
| 72 | MYLK | 0.51257914 |
| 73 | PIM1 | 0.50534910 |
| 74 | IRAK4 | 0.48249395 |
| 75 | SGK3 | 0.45946557 |
| 76 | PRKCQ | 0.44565646 |
| 77 | CSF1R | 0.43228041 |
| 78 | GRK6 | 0.39907629 |
| 79 | DAPK1 | 0.38157272 |
| 80 | CDK19 | 0.36993527 |
| 81 | GSK3A | 0.35622235 |
| 82 | PDK1 | 0.33666825 |
| 83 | BLK | 0.33351208 |
| 84 | PAK4 | 0.29694633 |
| 85 | KIT | 0.28990664 |
| 86 | ERN1 | 0.28692049 |
| 87 | MAP2K6 | 0.28552318 |
| 88 | EPHB1 | 0.27753281 |
| 89 | STK38 | 0.27402275 |
| 90 | CSNK1A1 | 0.27125134 |
| 91 | PDK2 | 0.26904148 |
| 92 | PAK1 | 0.26194402 |
| 93 | CAMKK2 | 0.25804163 |
| 94 | MAPK11 | 0.25048011 |
| 95 | SMG1 | 0.24863564 |
| 96 | PRKCH | 0.24721855 |
| 97 | ADRBK1 | 0.22883093 |
| 98 | PRKCZ | 0.21015938 |
| 99 | PASK | 0.19883279 |
| 100 | TYRO3 | 0.19167227 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.26382339 |
| 2 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 4.42414100 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.67430337 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.28472367 |
| 5 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 3.10775085 |
| 6 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.98696684 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.83431810 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.56957232 |
| 9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.50489482 |
| 10 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 2.32058092 |
| 11 | Measles_Homo sapiens_hsa05162 | 2.19399701 |
| 12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.06433127 |
| 13 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.98255371 |
| 14 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.84029028 |
| 15 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.81717146 |
| 16 | Legionellosis_Homo sapiens_hsa05134 | 1.75115859 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.71525763 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.67447999 |
| 19 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.59345318 |
| 20 | Leishmaniasis_Homo sapiens_hsa05140 | 1.52515563 |
| 21 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.50997189 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.47548367 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.40734794 |
| 24 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.33504625 |
| 25 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.30407365 |
| 26 | Hepatitis B_Homo sapiens_hsa05161 | 1.29119604 |
| 27 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.24959094 |
| 28 | Malaria_Homo sapiens_hsa05144 | 1.24667154 |
| 29 | Viral myocarditis_Homo sapiens_hsa05416 | 1.20803188 |
| 30 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.20237929 |
| 31 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.19640312 |
| 32 | Apoptosis_Homo sapiens_hsa04210 | 1.18500405 |
| 33 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.15268045 |
| 34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.13257542 |
| 35 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.12336709 |
| 36 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.11095004 |
| 37 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.06868095 |
| 38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.06854436 |
| 39 | Tuberculosis_Homo sapiens_hsa05152 | 1.00863820 |
| 40 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.98312731 |
| 41 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.96963675 |
| 42 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.86407655 |
| 43 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.84432165 |
| 44 | Influenza A_Homo sapiens_hsa05164 | 0.83506081 |
| 45 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.81735261 |
| 46 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.75901477 |
| 47 | HTLV-I infection_Homo sapiens_hsa05166 | 0.75742437 |
| 48 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.75340074 |
| 49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.73511402 |
| 50 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.73079940 |
| 51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.71581485 |
| 52 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68405466 |
| 53 | Hepatitis C_Homo sapiens_hsa05160 | 0.67527557 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.64519283 |
| 55 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.63897048 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.63694564 |
| 57 | RNA transport_Homo sapiens_hsa03013 | 0.63115945 |
| 58 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.62856688 |
| 59 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.55609119 |
| 60 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.52648243 |
| 61 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.51847178 |
| 62 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.51614521 |
| 63 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.51267612 |
| 64 | Insulin resistance_Homo sapiens_hsa04931 | 0.49937289 |
| 65 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.49192907 |
| 66 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47575222 |
| 67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46894627 |
| 68 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.46459806 |
| 69 | Shigellosis_Homo sapiens_hsa05131 | 0.42554687 |
| 70 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41463097 |
| 71 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.41107773 |
| 72 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.41062221 |
| 73 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.40570485 |
| 74 | Colorectal cancer_Homo sapiens_hsa05210 | 0.39321622 |
| 75 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.36537248 |
| 76 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.35786446 |
| 77 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.35281977 |
| 78 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.34748222 |
| 79 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.34678150 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.34138843 |
| 81 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.30571138 |
| 82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.27038486 |
| 83 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.25298315 |
| 84 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.24790824 |
| 85 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.23972789 |
| 86 | Pertussis_Homo sapiens_hsa05133 | 0.23637657 |
| 87 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.23018853 |
| 88 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.22763399 |
| 89 | Endometrial cancer_Homo sapiens_hsa05213 | 0.22418458 |
| 90 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.22159844 |
| 91 | Phototransduction_Homo sapiens_hsa04744 | 0.21893651 |
| 92 | Platelet activation_Homo sapiens_hsa04611 | 0.21803140 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.21447105 |
| 94 | Prostate cancer_Homo sapiens_hsa05215 | 0.20912630 |
| 95 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.19644984 |
| 96 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.18086162 |
| 97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.17877337 |
| 98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.17427932 |
| 99 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.16660858 |
| 100 | Bladder cancer_Homo sapiens_hsa05219 | 0.16123618 |

