TRAV26-1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to interleukin-15 (GO:0070672)6.40739978
2cellular response to interleukin-15 (GO:0071350)6.31178279
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.17779764
4negative regulation of cell killing (GO:0031342)6.17779764
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.14664755
6negative T cell selection (GO:0043383)5.97205677
7negative thymic T cell selection (GO:0045060)5.94053745
8positive regulation of gamma-delta T cell activation (GO:0046645)5.90280345
9cytidine deamination (GO:0009972)5.86494197
10cytidine metabolic process (GO:0046087)5.86494197
11cytidine catabolic process (GO:0006216)5.86494197
12positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.73316464
13regulation of B cell receptor signaling pathway (GO:0050855)5.71884512
14antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.60121868
15positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.59464504
16regulation of isotype switching to IgG isotypes (GO:0048302)5.47726313
17tolerance induction (GO:0002507)5.39467552
18pyrimidine ribonucleoside catabolic process (GO:0046133)5.30920594
19regulation of regulatory T cell differentiation (GO:0045589)5.30023848
20antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.16222625
21antigen processing and presentation of endogenous antigen (GO:0019883)5.00510729
22thymic T cell selection (GO:0045061)4.92073911
23regulation of T cell tolerance induction (GO:0002664)4.91093347
24regulation of gamma-delta T cell differentiation (GO:0045586)4.89919798
25positive regulation of B cell differentiation (GO:0045579)4.84297896
26positive T cell selection (GO:0043368)4.82344852
27regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.71938843
28regulation of interleukin-2 biosynthetic process (GO:0045076)4.68573895
29positive thymic T cell selection (GO:0045059)4.66947560
30T cell selection (GO:0045058)4.55584545
31regulation of gamma-delta T cell activation (GO:0046643)4.48483779
32T cell receptor signaling pathway (GO:0050852)4.46376718
33regulation of natural killer cell mediated immunity (GO:0002715)4.44138561
34regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.44138561
35positive regulation of granulocyte differentiation (GO:0030854)4.39945651
36activated T cell proliferation (GO:0050798)4.35802210
37negative regulation of T cell apoptotic process (GO:0070233)4.27493418
38DNA deamination (GO:0045006)4.25710219
39interferon-gamma production (GO:0032609)4.25264712
40regulation of B cell differentiation (GO:0045577)4.18212617
41positive regulation of natural killer cell mediated immunity (GO:0002717)4.16009358
42positive regulation of tolerance induction (GO:0002645)4.13763882
43cellular response to type I interferon (GO:0071357)4.08494541
44type I interferon signaling pathway (GO:0060337)4.08494541
45antigen receptor-mediated signaling pathway (GO:0050851)4.08368604
46regulation of tolerance induction (GO:0002643)4.07858789
47response to interferon-beta (GO:0035456)4.06833242
48regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.04044030
49negative regulation of T cell mediated immunity (GO:0002710)4.03941653
50response to type I interferon (GO:0034340)4.02468432
51cellular response to interferon-beta (GO:0035458)4.00277940
52antigen processing and presentation via MHC class Ib (GO:0002475)3.99340245
53leukocyte aggregation (GO:0070486)3.97197711
54positive regulation of interleukin-4 production (GO:0032753)3.92573924
55regulation of alpha-beta T cell proliferation (GO:0046640)3.91276723
56positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.86549305
57negative regulation of lymphocyte mediated immunity (GO:0002707)3.86239751
58positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.84291375
59regulation of leukocyte mediated cytotoxicity (GO:0001910)3.82048889
60mast cell activation (GO:0045576)3.80246644
61regulation of chronic inflammatory response (GO:0002676)3.77576005
62regulation of T cell mediated cytotoxicity (GO:0001914)3.73450028
63T cell migration (GO:0072678)3.72902860
64regulation of T cell receptor signaling pathway (GO:0050856)3.68523718
65regulation of cell killing (GO:0031341)3.65304556
66alpha-beta T cell differentiation (GO:0046632)3.63434307
67negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.63372135
68lymphocyte costimulation (GO:0031294)3.60624840
69T cell costimulation (GO:0031295)3.60326410
70positive regulation of T cell mediated cytotoxicity (GO:0001916)3.59724973
71T cell homeostasis (GO:0043029)3.59226209
72negative regulation of viral genome replication (GO:0045071)3.56039183
73positive regulation of alpha-beta T cell proliferation (GO:0046641)3.52878828
74positive regulation of cell killing (GO:0031343)3.51446589
75negative regulation of leukocyte mediated immunity (GO:0002704)3.50378217
76negative regulation of interleukin-12 production (GO:0032695)3.42344802
77regulation of T cell apoptotic process (GO:0070232)3.31653284
78positive regulation of interleukin-2 production (GO:0032743)3.30165514
79positive regulation of isotype switching (GO:0045830)3.29666700
80regulation of interleukin-4 production (GO:0032673)3.26966999
81T cell differentiation (GO:0030217)3.24213037
82alpha-beta T cell activation (GO:0046631)3.21913949
83negative regulation of T cell receptor signaling pathway (GO:0050860)3.20604927
84cellular defense response (GO:0006968)3.19914753
85regulation of granulocyte differentiation (GO:0030852)3.18334087
86regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.17204087
87NIK/NF-kappaB signaling (GO:0038061)3.17169522
88positive regulation of DNA recombination (GO:0045911)3.07832824
89CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.06819316
90CD4-positive, alpha-beta T cell differentiation (GO:0043367)3.06338315
91lymphocyte homeostasis (GO:0002260)3.05961763
92regulation of alpha-beta T cell activation (GO:0046634)3.02884687
93regulation of isotype switching (GO:0045191)3.02692526
94regulation of activation of Janus kinase activity (GO:0010533)3.02558088
95negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.00301768
96positive regulation of lymphocyte mediated immunity (GO:0002708)2.98224912
97regulation of T cell chemotaxis (GO:0010819)2.97763903
98positive regulation of T cell chemotaxis (GO:0010820)2.97763903
99pyrimidine nucleoside catabolic process (GO:0046135)2.97603914
100positive regulation of defense response to virus by host (GO:0002230)2.95910193

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.40438850
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.94013796
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.14848859
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.73437884
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.03297150
6RUNX_20019798_ChIP-Seq_JUKART_Human3.69592372
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.67114935
8STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.49267483
9MYB_26560356_Chip-Seq_TH2_Human3.43888740
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.35445987
11STAT4_19710469_ChIP-ChIP_TH1__Mouse3.31677912
12MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.99307075
13MYB_26560356_Chip-Seq_TH1_Human2.87885890
14MAF_26560356_Chip-Seq_TH1_Human2.82400584
15FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.67963652
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.62806369
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.55040346
18UTX_26944678_Chip-Seq_JUKART_Human2.39094219
19RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.35138677
20GATA3_27048872_Chip-Seq_THYMUS_Human2.34839662
21MAF_26560356_Chip-Seq_TH2_Human2.26738936
22SMAD_19615063_ChIP-ChIP_OVARY_Human2.19398732
23IRF8_27001747_Chip-Seq_BMDM_Mouse2.14763408
24SPI1_23547873_ChIP-Seq_NB4_Human2.10398348
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.06875533
26GATA3_26560356_Chip-Seq_TH2_Human2.01365509
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.96268657
28FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.90971186
29SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.88948090
30MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.83001288
31E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.82148396
32NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.81239827
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.77422433
34SCL_19346495_ChIP-Seq_HPC-7_Human1.74252986
35MYC_22102868_ChIP-Seq_BL_Human1.73483599
36STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.67118882
37ELF1_17652178_ChIP-ChIP_JURKAT_Human1.64759267
38RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.61895977
39CIITA_25753668_ChIP-Seq_RAJI_Human1.57815834
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.57469686
41MYB_21317192_ChIP-Seq_ERMYB_Mouse1.57220421
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56968692
43STAT6_21828071_ChIP-Seq_BEAS2B_Human1.56866372
44LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.56678708
45SPI1_23127762_ChIP-Seq_K562_Human1.40404993
46RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.38585894
47VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36494126
48KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.34289999
49VDR_24763502_ChIP-Seq_THP-1_Human1.28885250
50VDR_21846776_ChIP-Seq_THP-1_Human1.28501456
51BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23354005
52CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22563521
53CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.22120943
54LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.20535834
55GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.19123582
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.18889430
57VDR_23849224_ChIP-Seq_CD4+_Human1.17048778
58BCL6_27268052_Chip-Seq_Bcells_Human1.16717057
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15455369
60FOXP3_21729870_ChIP-Seq_TREG_Human1.14940672
61TCF7_22412390_ChIP-Seq_EML_Mouse1.10285982
62KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.05466126
63ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.04789446
64VDR_24787735_ChIP-Seq_THP-1_Human1.04436711
65CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04270060
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03880988
67PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03471531
68CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.03288883
69GATA2_22383799_ChIP-Seq_G1ME_Mouse1.03165437
70SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01291130
71KDM2B_26808549_Chip-Seq_DND41_Human1.00855770
72NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.00295584
73KDM2B_26808549_Chip-Seq_SUP-B15_Human0.99694588
74TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96382031
75PU.1_20513432_ChIP-Seq_Bcells_Mouse0.94464823
76NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.91774830
77TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91085086
78BCOR_27268052_Chip-Seq_Bcells_Human0.89066768
79RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88795739
80EGR1_19032775_ChIP-ChIP_M12_Human0.88727662
81CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87434248
82CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.87108581
83PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86150018
84TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.85928312
85PU_27001747_Chip-Seq_BMDM_Mouse0.84996702
86KDM2B_26808549_Chip-Seq_JURKAT_Human0.84117980
87STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.83039937
88FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81879292
89PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81078204
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79936141
91GATA1_19941827_ChIP-Seq_MEL_Mouse0.77604116
92Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.75133703
93GATA1_22383799_ChIP-Seq_G1ME_Mouse0.73048986
94GATA3_26560356_Chip-Seq_TH1_Human0.72323976
95PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.70561246
96VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.69274194
97GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69088055
98GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.68746514
99FLI1_27457419_Chip-Seq_LIVER_Mouse0.68177725
100SA1_27219007_Chip-Seq_Bcells_Human0.68169609

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology5.08307553
2MP0005671_abnormal_response_to4.80996469
3MP0001873_stomach_inflammation3.71439113
4MP0001835_abnormal_antigen_presentation3.66131506
5MP0009333_abnormal_splenocyte_physiolog3.42503041
6MP0001800_abnormal_humoral_immune3.35874883
7MP0005000_abnormal_immune_tolerance3.19062174
8MP0003436_decreased_susceptibility_to2.98455459
9MP0002723_abnormal_immune_serum2.90367733
10MP0009785_altered_susceptibility_to2.80688970
11MP0005025_abnormal_response_to2.75293197
12MP0002420_abnormal_adaptive_immunity2.74698163
13MP0003866_abnormal_defecation2.71513947
14MP0001819_abnormal_immune_cell2.68943801
15MP0000703_abnormal_thymus_morphology2.64716206
16MP0002638_abnormal_pupillary_reflex2.61643125
17MP0005387_immune_system_phenotype2.59757403
18MP0001790_abnormal_immune_system2.59757403
19MP0000685_abnormal_immune_system2.56292957
20MP0002452_abnormal_antigen_presenting2.49652431
21MP0002398_abnormal_bone_marrow2.45946097
22MP0002405_respiratory_system_inflammati2.41174949
23MP0000716_abnormal_immune_system2.33331751
24MP0003724_increased_susceptibility_to2.28307892
25MP0002148_abnormal_hypersensitivity_rea2.20850934
26MP0010155_abnormal_intestine_physiology2.14431328
27MP0002419_abnormal_innate_immunity2.11778680
28MP0002722_abnormal_immune_system2.01437115
29MP0006082_CNS_inflammation2.01206742
30MP0000689_abnormal_spleen_morphology2.00877789
31MP0004947_skin_inflammation1.96706174
32MP0005464_abnormal_platelet_physiology1.96195195
33MP0003300_gastrointestinal_ulcer1.94977259
34MP0004381_abnormal_hair_follicle1.92273277
35MP0002166_altered_tumor_susceptibility1.90326040
36MP0001853_heart_inflammation1.81407804
37MP0002429_abnormal_blood_cell1.79073814
38MP0001845_abnormal_inflammatory_respons1.71892245
39MP0005310_abnormal_salivary_gland1.71857655
40MP0002277_abnormal_respiratory_mucosa1.61591723
41MP0002933_joint_inflammation1.56542044
42MP0003646_muscle_fatigue1.49018057
43MP0003045_fibrosis1.45346096
44MP0005075_abnormal_melanosome_morpholog1.44441704
45MP0002163_abnormal_gland_morphology1.41571525
46MP0001533_abnormal_skeleton_physiology1.36942220
47MP0003303_peritoneal_inflammation1.31425948
48MP0002006_tumorigenesis1.30713832
49MP0008057_abnormal_DNA_replication1.23414386
50MP0008469_abnormal_protein_level1.20922173
51MP0003191_abnormal_cellular_cholesterol1.16658830
52MP0002396_abnormal_hematopoietic_system1.13458575
53MP0000858_altered_metastatic_potential1.11512931
54MP0001663_abnormal_digestive_system1.08947754
55MP0000372_irregular_coat_pigmentation1.04314221
56MP0002132_abnormal_respiratory_system1.04035779
57MP0002138_abnormal_hepatobiliary_system0.98567966
58MP0002009_preneoplasia0.93725433
59MP0009764_decreased_sensitivity_to0.93348291
60MP0000465_gastrointestinal_hemorrhage0.93236462
61MP0002998_abnormal_bone_remodeling0.92734694
62MP0001851_eye_inflammation0.87915691
63MP0001764_abnormal_homeostasis0.86827397
64MP0003806_abnormal_nucleotide_metabolis0.86334414
65MP0001348_abnormal_lacrimal_gland0.84890786
66MP0003448_altered_tumor_morphology0.84559267
67MP0004142_abnormal_muscle_tone0.83519586
68MP0009763_increased_sensitivity_to0.78186494
69MP0002693_abnormal_pancreas_physiology0.75850435
70MP0003183_abnormal_peptide_metabolism0.75733925
71MP0005379_endocrine/exocrine_gland_phen0.73518602
72MP0001986_abnormal_taste_sensitivity0.72704774
73MP0003172_abnormal_lysosome_physiology0.67457163
74MP0005381_digestive/alimentary_phenotyp0.64370953
75MP0001919_abnormal_reproductive_system0.64043892
76MP0002019_abnormal_tumor_incidence0.61456537
77MP0003786_premature_aging0.60968923
78MP0005390_skeleton_phenotype0.60754155
79MP0005409_darkened_coat_color0.58087431
80MP0005377_hearing/vestibular/ear_phenot0.57870082
81MP0003878_abnormal_ear_physiology0.57870082
82MP0004036_abnormal_muscle_relaxation0.57581823
83MP0000490_abnormal_crypts_of0.56471506
84MP0001502_abnormal_circadian_rhythm0.53162442
85MP0002837_dystrophic_cardiac_calcinosis0.52565049
86MP0000569_abnormal_digit_pigmentation0.51091754
87MP0005376_homeostasis/metabolism_phenot0.50240952
88MP0003795_abnormal_bone_structure0.50147810
89MP0004130_abnormal_muscle_cell0.49886284
90MP0004510_myositis0.49762853
91MP0005266_abnormal_metabolism0.46317252
92MP0008260_abnormal_autophagy0.46090324
93MP0005166_decreased_susceptibility_to0.45680208
94MP0009765_abnormal_xenobiotic_induced0.43990498
95MP0002332_abnormal_exercise_endurance0.43495833
96MP0001765_abnormal_ion_homeostasis0.40692807
97MP0002136_abnormal_kidney_physiology0.40684801
98MP0000249_abnormal_blood_vessel0.38742404
99MP0000470_abnormal_stomach_morphology0.38718410
100MP0008872_abnormal_physiological_respon0.36740442

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)7.58358574
2Stomatitis (HP:0010280)6.70545069
3T lymphocytopenia (HP:0005403)5.91551140
4Abnormal delayed hypersensitivity skin test (HP:0002963)5.47352326
5Abnormality of T cell number (HP:0011839)5.45483964
6Autoimmune hemolytic anemia (HP:0001890)5.34266157
7IgG deficiency (HP:0004315)5.16160998
8Eczematoid dermatitis (HP:0000976)4.85817249
9Abnormality of T cells (HP:0002843)4.80930634
10Recurrent cutaneous fungal infections (HP:0011370)4.67296038
11Chronic mucocutaneous candidiasis (HP:0002728)4.67296038
12Panhypogammaglobulinemia (HP:0003139)4.42350330
13Recurrent fungal infections (HP:0002841)4.38575179
14Aplastic anemia (HP:0001915)4.35232438
15Severe combined immunodeficiency (HP:0004430)4.10297377
16Encephalitis (HP:0002383)3.94531081
17IgM deficiency (HP:0002850)3.79883775
18Myositis (HP:0100614)3.77555038
19Meningitis (HP:0001287)3.75419170
20Increased IgM level (HP:0003496)3.74787467
21Abnormality of macrophages (HP:0004311)3.67851874
22Vasculitis (HP:0002633)3.67149891
23Chronic diarrhea (HP:0002028)3.63750557
24Hypoplasia of the thymus (HP:0000778)3.63747419
25Gastrointestinal infarctions (HP:0005244)3.61895302
26Abnormality of T cell physiology (HP:0011840)3.54197730
27Recurrent bronchitis (HP:0002837)3.53201469
28Pustule (HP:0200039)3.49731953
29Increased IgE level (HP:0003212)3.37358201
30Optic neuritis (HP:0100653)3.35745394
31Retrobulbar optic neuritis (HP:0100654)3.35745394
32Abnormality of eosinophils (HP:0001879)3.35487491
33Pulmonary infiltrates (HP:0002113)3.34371832
34Obstructive lung disease (HP:0006536)3.30497203
35Chronic obstructive pulmonary disease (HP:0006510)3.30497203
36Leukocytosis (HP:0001974)3.27115500
37Orchitis (HP:0100796)3.25783783
38Lymphopenia (HP:0001888)3.25175246
39Agammaglobulinemia (HP:0004432)3.24528104
40Recurrent skin infections (HP:0001581)3.21712557
41Spontaneous hematomas (HP:0007420)3.19147661
42Combined immunodeficiency (HP:0005387)3.17146314
43Recurrent bacterial skin infections (HP:0005406)3.16047050
44Joint swelling (HP:0001386)3.10742888
45Recurrent viral infections (HP:0004429)3.08118630
46Abnormality of cells of the lymphoid lineage (HP:0012140)3.01028490
47Recurrent abscess formation (HP:0002722)3.00052204
48Mediastinal lymphadenopathy (HP:0100721)2.98183868
49Thyroiditis (HP:0100646)2.97055844
50Eosinophilia (HP:0001880)2.84251330
51Chest pain (HP:0100749)2.83923926
52Granulocytopenia (HP:0001913)2.76463595
53Hemoptysis (HP:0002105)2.72755658
54Lymphoma (HP:0002665)2.68247728
55Pulmonary embolism (HP:0002204)2.67112439
56Petechiae (HP:0000967)2.66416608
57Hypergammaglobulinemia (HP:0010702)2.60864338
58Keratoconjunctivitis sicca (HP:0001097)2.59166295
59Cutaneous melanoma (HP:0012056)2.53745210
60Hypochromic anemia (HP:0001931)2.44350639
61Microcytic anemia (HP:0001935)2.43420660
62Hypochromic microcytic anemia (HP:0004840)2.41493097
63Abnormality of the prostate (HP:0008775)2.41356010
64Inflammation of the large intestine (HP:0002037)2.37596629
65Keratoconjunctivitis (HP:0001096)2.36511613
66Glomerulopathy (HP:0100820)2.32761615
67Gastrointestinal inflammation (HP:0004386)2.29139892
68Skin rash (HP:0000988)2.28335286
69Gangrene (HP:0100758)2.28272997
70Papilledema (HP:0001085)2.25627881
71Ureteral stenosis (HP:0000071)2.25385142
72Basal ganglia calcification (HP:0002135)2.23514539
73Abnormality of the fingertips (HP:0001211)2.20476022
74Abnormality of the pleura (HP:0002103)2.19111757
75Epistaxis (HP:0000421)2.18372794
76Urticaria (HP:0001025)2.17712946
77Bilateral sensorineural hearing impairment (HP:0008619)2.15392334
78Ureteral obstruction (HP:0006000)2.14121807
79Hypoproteinemia (HP:0003075)2.12832496
80Prolonged bleeding time (HP:0003010)2.10912922
81Abnormality of the pericardium (HP:0001697)2.08813971
82Acute hepatic failure (HP:0006554)2.07981112
83Purpura (HP:0000979)2.06939596
84Bronchitis (HP:0012387)2.05449454
85Stomach cancer (HP:0012126)2.05000612
86Abnormality of B cell number (HP:0010975)2.03702590
87Anomalous pulmonary venous return (HP:0010772)2.03630194
88Restrictive lung disease (HP:0002091)2.02278291
89Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.98905387
90Colitis (HP:0002583)1.98540872
91Episodic fever (HP:0001954)1.97079389
92Aplasia/Hypoplasia of the thymus (HP:0010515)1.93333502
93Sepsis (HP:0100806)1.93259847
94Chronic otitis media (HP:0000389)1.92312070
95Alveolar cell carcinoma (HP:0006519)1.88548279
96Basal cell carcinoma (HP:0002671)1.88375295
97Pancytopenia (HP:0001876)1.87273867
98Hyperlipoproteinemia (HP:0010980)1.86976464
99Arterial thrombosis (HP:0004420)1.86774020
100Gingivitis (HP:0000230)1.85958408

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK7.50275064
2MAP4K14.79420739
3ITK3.01829042
4SIK32.98596931
5FGFR42.91036262
6ZAP702.79848029
7FES2.60089733
8EPHA32.53650071
9JAK32.47562098
10NLK2.35294140
11EPHB12.31223019
12IRAK42.20542695
13CSK2.20541021
14BTK2.11126916
15TYK22.04632725
16RIPK41.85563660
17LCK1.80644839
18FGFR31.79429318
19TEC1.79389441
20JAK11.73798265
21SIK21.70653833
22TNK21.67930587
23SYK1.66511212
24HCK1.62252680
25MAP3K111.54580680
26IKBKE1.47830542
27PASK1.40544902
28MAP2K31.35190110
29MARK31.33978069
30SIK11.33803778
31GRK61.30768623
32PRPF4B1.29512394
33MAP3K31.29402181
34MST41.23694003
35BLK1.17100609
36TAOK31.15836332
37IRAK11.10313224
38LYN1.09284142
39PRKCQ1.04507312
40IKBKB1.03538830
41KDR0.98481103
42TYRO30.93554867
43TESK20.90488732
44FGFR20.87758637
45JAK20.87565947
46FGR0.78620752
47MAP3K140.76293684
48MAPK120.76125581
49CAMKK10.74653712
50SGK30.74590677
51PDGFRB0.74376545
52CAMKK20.74279228
53HIPK20.73944181
54STK38L0.72287439
55TBK10.72029744
56FYN0.67204719
57ERN10.65123486
58STK380.63567815
59ADRBK20.60498696
60MAPK110.59896500
61KIT0.59656359
62MAP3K10.58729611
63MAP3K130.56689013
64SGK20.56069670
65CDK190.55897918
66CSF1R0.49047461
67MELK0.48988318
68AKT30.45102784
69STK100.44906003
70CLK10.44883305
71PIM10.44839770
72RET0.44402177
73MAP3K100.44166687
74CHUK0.43623498
75IGF1R0.36469167
76GRK70.35884461
77RPS6KA50.34318914
78TAOK10.34311390
79SGK4940.32685782
80SGK2230.32685782
81CAMK40.32095585
82ALK0.31980457
83SCYL20.31421286
84TAOK20.30826435
85STK240.30752727
86MAPKAPK20.30152116
87PDK10.29086318
88CDK40.27357338
89PRKCH0.25246515
90RPS6KA40.24628245
91INSR0.23124968
92MAP2K60.22042883
93MARK20.21122097
94LRRK20.19330258
95PRKCD0.17504160
96MAPK30.16712782
97NTRK20.16653653
98NUAK10.16498811
99SMG10.14467948
100EGFR0.12911014

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.36781280
2T cell receptor signaling pathway_Homo sapiens_hsa046603.69633870
3Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.54421308
4Autoimmune thyroid disease_Homo sapiens_hsa053203.26855748
5Measles_Homo sapiens_hsa051623.09972158
6Allograft rejection_Homo sapiens_hsa053303.09164142
7Antigen processing and presentation_Homo sapiens_hsa046122.99513178
8Graft-versus-host disease_Homo sapiens_hsa053322.80859592
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.64992915
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.49537345
11Hematopoietic cell lineage_Homo sapiens_hsa046402.44619202
12Type I diabetes mellitus_Homo sapiens_hsa049402.05472525
13Osteoclast differentiation_Homo sapiens_hsa043802.05378260
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.84164002
15Intestinal immune network for IgA production_Homo sapiens_hsa046721.79778385
16Jak-STAT signaling pathway_Homo sapiens_hsa046301.73547998
17Chemokine signaling pathway_Homo sapiens_hsa040621.69283210
18Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.62799995
19Viral myocarditis_Homo sapiens_hsa054161.60727524
20Herpes simplex infection_Homo sapiens_hsa051681.58326687
21Leishmaniasis_Homo sapiens_hsa051401.57468734
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.54107978
23Malaria_Homo sapiens_hsa051441.49844629
24B cell receptor signaling pathway_Homo sapiens_hsa046621.46337906
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.41080836
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.35416656
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.34618134
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.28528915
29Acute myeloid leukemia_Homo sapiens_hsa052211.27120674
30TNF signaling pathway_Homo sapiens_hsa046681.24963495
31NOD-like receptor signaling pathway_Homo sapiens_hsa046211.18203381
32Asthma_Homo sapiens_hsa053101.17639746
33Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.17342193
34Staphylococcus aureus infection_Homo sapiens_hsa051501.15053874
35Rheumatoid arthritis_Homo sapiens_hsa053231.12166105
36Shigellosis_Homo sapiens_hsa051311.09932383
37Influenza A_Homo sapiens_hsa051641.04337447
38Viral carcinogenesis_Homo sapiens_hsa052031.00042877
39Toxoplasmosis_Homo sapiens_hsa051450.97493777
40HTLV-I infection_Homo sapiens_hsa051660.94585054
41Platelet activation_Homo sapiens_hsa046110.94567267
42Non-small cell lung cancer_Homo sapiens_hsa052230.92771590
43Tuberculosis_Homo sapiens_hsa051520.92704540
44Hepatitis B_Homo sapiens_hsa051610.92065001
45Pancreatic cancer_Homo sapiens_hsa052120.89889506
46Leukocyte transendothelial migration_Homo sapiens_hsa046700.86953175
47Apoptosis_Homo sapiens_hsa042100.84013460
48Hepatitis C_Homo sapiens_hsa051600.81143195
49Epstein-Barr virus infection_Homo sapiens_hsa051690.80949913
50Regulation of autophagy_Homo sapiens_hsa041400.72240447
51African trypanosomiasis_Homo sapiens_hsa051430.68256781
522-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.66642776
53Basal transcription factors_Homo sapiens_hsa030220.65018519
54Salmonella infection_Homo sapiens_hsa051320.63513631
55Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63446071
56FoxO signaling pathway_Homo sapiens_hsa040680.63144522
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62519598
58Prolactin signaling pathway_Homo sapiens_hsa049170.62293533
59Legionellosis_Homo sapiens_hsa051340.61175749
60VEGF signaling pathway_Homo sapiens_hsa043700.59249473
61Insulin resistance_Homo sapiens_hsa049310.59153910
62Adipocytokine signaling pathway_Homo sapiens_hsa049200.59103438
63Dorso-ventral axis formation_Homo sapiens_hsa043200.58714673
64Endocytosis_Homo sapiens_hsa041440.57552212
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.48158757
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.46356953
67Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46099660
68Sphingolipid signaling pathway_Homo sapiens_hsa040710.45820798
69Chronic myeloid leukemia_Homo sapiens_hsa052200.45044708
70Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44901122
71Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44472308
72Collecting duct acid secretion_Homo sapiens_hsa049660.42679052
73MAPK signaling pathway_Homo sapiens_hsa040100.38041644
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.37588629
75Pertussis_Homo sapiens_hsa051330.37247107
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37119916
77Ras signaling pathway_Homo sapiens_hsa040140.36003262
78Phototransduction_Homo sapiens_hsa047440.33875528
79Ribosome_Homo sapiens_hsa030100.32969797
80Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.32578051
81Linoleic acid metabolism_Homo sapiens_hsa005910.32567568
82Phagosome_Homo sapiens_hsa041450.30434305
83Olfactory transduction_Homo sapiens_hsa047400.29568488
84Thyroid cancer_Homo sapiens_hsa052160.29430910
85Arginine biosynthesis_Homo sapiens_hsa002200.26702837
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.25886267
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.24417660
88Notch signaling pathway_Homo sapiens_hsa043300.24279260
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.24142570
90Colorectal cancer_Homo sapiens_hsa052100.22668954
91Carbohydrate digestion and absorption_Homo sapiens_hsa049730.22009151
92Choline metabolism in cancer_Homo sapiens_hsa052310.21499582
93Inositol phosphate metabolism_Homo sapiens_hsa005620.19992686
94Morphine addiction_Homo sapiens_hsa050320.19927880
95Cholinergic synapse_Homo sapiens_hsa047250.19758965
96Glycerolipid metabolism_Homo sapiens_hsa005610.19729820
97Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.19350258
98Renal cell carcinoma_Homo sapiens_hsa052110.18977293
99Long-term potentiation_Homo sapiens_hsa047200.18624126
100Proteasome_Homo sapiens_hsa030500.18255615

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »