

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to interleukin-15 (GO:0070672) | 6.40739978 |
| 2 | cellular response to interleukin-15 (GO:0071350) | 6.31178279 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.17779764 |
| 4 | negative regulation of cell killing (GO:0031342) | 6.17779764 |
| 5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.14664755 |
| 6 | negative T cell selection (GO:0043383) | 5.97205677 |
| 7 | negative thymic T cell selection (GO:0045060) | 5.94053745 |
| 8 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.90280345 |
| 9 | cytidine metabolic process (GO:0046087) | 5.86494197 |
| 10 | cytidine catabolic process (GO:0006216) | 5.86494197 |
| 11 | cytidine deamination (GO:0009972) | 5.86494197 |
| 12 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.73316464 |
| 13 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.71884512 |
| 14 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.60121868 |
| 15 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.59464504 |
| 16 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.47726313 |
| 17 | tolerance induction (GO:0002507) | 5.39467552 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.30920594 |
| 19 | regulation of regulatory T cell differentiation (GO:0045589) | 5.30023848 |
| 20 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.16222625 |
| 21 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.00510729 |
| 22 | thymic T cell selection (GO:0045061) | 4.92073911 |
| 23 | regulation of T cell tolerance induction (GO:0002664) | 4.91093347 |
| 24 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.89919798 |
| 25 | positive regulation of B cell differentiation (GO:0045579) | 4.84297896 |
| 26 | positive T cell selection (GO:0043368) | 4.82344852 |
| 27 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.71938843 |
| 28 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.68573895 |
| 29 | positive thymic T cell selection (GO:0045059) | 4.66947560 |
| 30 | T cell selection (GO:0045058) | 4.55584545 |
| 31 | regulation of gamma-delta T cell activation (GO:0046643) | 4.48483779 |
| 32 | T cell receptor signaling pathway (GO:0050852) | 4.46376718 |
| 33 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.44138561 |
| 34 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.44138561 |
| 35 | positive regulation of granulocyte differentiation (GO:0030854) | 4.39945651 |
| 36 | activated T cell proliferation (GO:0050798) | 4.35802210 |
| 37 | negative regulation of T cell apoptotic process (GO:0070233) | 4.27493418 |
| 38 | DNA deamination (GO:0045006) | 4.25710219 |
| 39 | interferon-gamma production (GO:0032609) | 4.25264712 |
| 40 | regulation of B cell differentiation (GO:0045577) | 4.18212617 |
| 41 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.16009358 |
| 42 | positive regulation of tolerance induction (GO:0002645) | 4.13763882 |
| 43 | type I interferon signaling pathway (GO:0060337) | 4.08494541 |
| 44 | cellular response to type I interferon (GO:0071357) | 4.08494541 |
| 45 | antigen receptor-mediated signaling pathway (GO:0050851) | 4.08368604 |
| 46 | regulation of tolerance induction (GO:0002643) | 4.07858789 |
| 47 | response to interferon-beta (GO:0035456) | 4.06833242 |
| 48 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.04044030 |
| 49 | negative regulation of T cell mediated immunity (GO:0002710) | 4.03941653 |
| 50 | response to type I interferon (GO:0034340) | 4.02468432 |
| 51 | cellular response to interferon-beta (GO:0035458) | 4.00277940 |
| 52 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.99340245 |
| 53 | leukocyte aggregation (GO:0070486) | 3.97197711 |
| 54 | positive regulation of interleukin-4 production (GO:0032753) | 3.92573924 |
| 55 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.91276723 |
| 56 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.86549305 |
| 57 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.86239751 |
| 58 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.84291375 |
| 59 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.82048889 |
| 60 | mast cell activation (GO:0045576) | 3.80246644 |
| 61 | regulation of chronic inflammatory response (GO:0002676) | 3.77576005 |
| 62 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.73450028 |
| 63 | T cell migration (GO:0072678) | 3.72902860 |
| 64 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.68523718 |
| 65 | regulation of cell killing (GO:0031341) | 3.65304556 |
| 66 | alpha-beta T cell differentiation (GO:0046632) | 3.63434307 |
| 67 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.63372135 |
| 68 | lymphocyte costimulation (GO:0031294) | 3.60624840 |
| 69 | T cell costimulation (GO:0031295) | 3.60326410 |
| 70 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.59724973 |
| 71 | T cell homeostasis (GO:0043029) | 3.59226209 |
| 72 | negative regulation of viral genome replication (GO:0045071) | 3.56039183 |
| 73 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.52878828 |
| 74 | positive regulation of cell killing (GO:0031343) | 3.51446589 |
| 75 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.50378217 |
| 76 | negative regulation of interleukin-12 production (GO:0032695) | 3.42344802 |
| 77 | regulation of T cell apoptotic process (GO:0070232) | 3.31653284 |
| 78 | positive regulation of interleukin-2 production (GO:0032743) | 3.30165514 |
| 79 | positive regulation of isotype switching (GO:0045830) | 3.29666700 |
| 80 | regulation of interleukin-4 production (GO:0032673) | 3.26966999 |
| 81 | T cell differentiation (GO:0030217) | 3.24213037 |
| 82 | alpha-beta T cell activation (GO:0046631) | 3.21913949 |
| 83 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.20604927 |
| 84 | cellular defense response (GO:0006968) | 3.19914753 |
| 85 | regulation of granulocyte differentiation (GO:0030852) | 3.18334087 |
| 86 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.17204087 |
| 87 | NIK/NF-kappaB signaling (GO:0038061) | 3.17169522 |
| 88 | positive regulation of DNA recombination (GO:0045911) | 3.07832824 |
| 89 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.06819316 |
| 90 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.06338315 |
| 91 | lymphocyte homeostasis (GO:0002260) | 3.05961763 |
| 92 | regulation of alpha-beta T cell activation (GO:0046634) | 3.02884687 |
| 93 | regulation of isotype switching (GO:0045191) | 3.02692526 |
| 94 | regulation of activation of Janus kinase activity (GO:0010533) | 3.02558088 |
| 95 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.00301768 |
| 96 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2.98224912 |
| 97 | positive regulation of T cell chemotaxis (GO:0010820) | 2.97763903 |
| 98 | regulation of T cell chemotaxis (GO:0010819) | 2.97763903 |
| 99 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.97603914 |
| 100 | positive regulation of defense response to virus by host (GO:0002230) | 2.95910193 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.40438850 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.94013796 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.14848859 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.73437884 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.03297150 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.69592372 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.67114935 |
| 8 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.49267483 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.43888740 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.35445987 |
| 11 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.31677912 |
| 12 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.99307075 |
| 13 | MYB_26560356_Chip-Seq_TH1_Human | 2.87885890 |
| 14 | MAF_26560356_Chip-Seq_TH1_Human | 2.82400584 |
| 15 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.67963652 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.62806369 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.55040346 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.39094219 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.35138677 |
| 20 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.34839662 |
| 21 | MAF_26560356_Chip-Seq_TH2_Human | 2.26738936 |
| 22 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.19398732 |
| 23 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.14763408 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.10398348 |
| 25 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.06875533 |
| 26 | GATA3_26560356_Chip-Seq_TH2_Human | 2.01365509 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.96268657 |
| 28 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.90971186 |
| 29 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.88948090 |
| 30 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83001288 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.82148396 |
| 32 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.81239827 |
| 33 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.77422433 |
| 34 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.74252986 |
| 35 | MYC_22102868_ChIP-Seq_BL_Human | 1.73483599 |
| 36 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.67118882 |
| 37 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.64759267 |
| 38 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.61895977 |
| 39 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.57815834 |
| 40 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.57469686 |
| 41 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.57220421 |
| 42 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.56968692 |
| 43 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.56866372 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56678708 |
| 45 | SPI1_23127762_ChIP-Seq_K562_Human | 1.40404993 |
| 46 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.38585894 |
| 47 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36494126 |
| 48 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.34289999 |
| 49 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.28885250 |
| 50 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.28501456 |
| 51 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.23354005 |
| 52 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.22563521 |
| 53 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22120943 |
| 54 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.20535834 |
| 55 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19123582 |
| 56 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.18889430 |
| 57 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.17048778 |
| 58 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.16717057 |
| 59 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15455369 |
| 60 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.14940672 |
| 61 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.10285982 |
| 62 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.05466126 |
| 63 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.04789446 |
| 64 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.04436711 |
| 65 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04270060 |
| 66 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03880988 |
| 67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.03471531 |
| 68 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.03288883 |
| 69 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.03165437 |
| 70 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.01291130 |
| 71 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.00855770 |
| 72 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.00295584 |
| 73 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.99694588 |
| 74 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96382031 |
| 75 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.94464823 |
| 76 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91774830 |
| 77 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.91085086 |
| 78 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.89066768 |
| 79 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.88795739 |
| 80 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.88727662 |
| 81 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87434248 |
| 82 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.87108581 |
| 83 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.86150018 |
| 84 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85928312 |
| 85 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.84996702 |
| 86 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.84117980 |
| 87 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.83039937 |
| 88 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.81879292 |
| 89 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.81078204 |
| 90 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.79936141 |
| 91 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.77604116 |
| 92 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.75133703 |
| 93 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.73048986 |
| 94 | GATA3_26560356_Chip-Seq_TH1_Human | 0.72323976 |
| 95 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.70561246 |
| 96 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.69274194 |
| 97 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.69088055 |
| 98 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.68746514 |
| 99 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.68177725 |
| 100 | SA1_27219007_Chip-Seq_Bcells_Human | 0.68169609 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 5.08307553 |
| 2 | MP0005671_abnormal_response_to | 4.80996469 |
| 3 | MP0001873_stomach_inflammation | 3.71439113 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.66131506 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 3.42503041 |
| 6 | MP0001800_abnormal_humoral_immune | 3.35874883 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.19062174 |
| 8 | MP0003436_decreased_susceptibility_to | 2.98455459 |
| 9 | MP0002723_abnormal_immune_serum | 2.90367733 |
| 10 | MP0009785_altered_susceptibility_to | 2.80688970 |
| 11 | MP0005025_abnormal_response_to | 2.75293197 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.74698163 |
| 13 | MP0003866_abnormal_defecation | 2.71513947 |
| 14 | MP0001819_abnormal_immune_cell | 2.68943801 |
| 15 | MP0000703_abnormal_thymus_morphology | 2.64716206 |
| 16 | MP0002638_abnormal_pupillary_reflex | 2.61643125 |
| 17 | MP0005387_immune_system_phenotype | 2.59757403 |
| 18 | MP0001790_abnormal_immune_system | 2.59757403 |
| 19 | MP0000685_abnormal_immune_system | 2.56292957 |
| 20 | MP0002452_abnormal_antigen_presenting | 2.49652431 |
| 21 | MP0002398_abnormal_bone_marrow | 2.45946097 |
| 22 | MP0002405_respiratory_system_inflammati | 2.41174949 |
| 23 | MP0000716_abnormal_immune_system | 2.33331751 |
| 24 | MP0003724_increased_susceptibility_to | 2.28307892 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 2.20850934 |
| 26 | MP0010155_abnormal_intestine_physiology | 2.14431328 |
| 27 | MP0002419_abnormal_innate_immunity | 2.11778680 |
| 28 | MP0002722_abnormal_immune_system | 2.01437115 |
| 29 | MP0006082_CNS_inflammation | 2.01206742 |
| 30 | MP0000689_abnormal_spleen_morphology | 2.00877789 |
| 31 | MP0004947_skin_inflammation | 1.96706174 |
| 32 | MP0005464_abnormal_platelet_physiology | 1.96195195 |
| 33 | MP0003300_gastrointestinal_ulcer | 1.94977259 |
| 34 | MP0004381_abnormal_hair_follicle | 1.92273277 |
| 35 | MP0002166_altered_tumor_susceptibility | 1.90326040 |
| 36 | MP0001853_heart_inflammation | 1.81407804 |
| 37 | MP0002429_abnormal_blood_cell | 1.79073814 |
| 38 | MP0001845_abnormal_inflammatory_respons | 1.71892245 |
| 39 | MP0005310_abnormal_salivary_gland | 1.71857655 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.61591723 |
| 41 | MP0002933_joint_inflammation | 1.56542044 |
| 42 | MP0003646_muscle_fatigue | 1.49018057 |
| 43 | MP0003045_fibrosis | 1.45346096 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.44441704 |
| 45 | MP0002163_abnormal_gland_morphology | 1.41571525 |
| 46 | MP0001533_abnormal_skeleton_physiology | 1.36942220 |
| 47 | MP0003303_peritoneal_inflammation | 1.31425948 |
| 48 | MP0002006_tumorigenesis | 1.30713832 |
| 49 | MP0008057_abnormal_DNA_replication | 1.23414386 |
| 50 | MP0008469_abnormal_protein_level | 1.20922173 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.16658830 |
| 52 | MP0002396_abnormal_hematopoietic_system | 1.13458575 |
| 53 | MP0000858_altered_metastatic_potential | 1.11512931 |
| 54 | MP0001663_abnormal_digestive_system | 1.08947754 |
| 55 | MP0000372_irregular_coat_pigmentation | 1.04314221 |
| 56 | MP0002132_abnormal_respiratory_system | 1.04035779 |
| 57 | MP0002138_abnormal_hepatobiliary_system | 0.98567966 |
| 58 | MP0002009_preneoplasia | 0.93725433 |
| 59 | MP0009764_decreased_sensitivity_to | 0.93348291 |
| 60 | MP0000465_gastrointestinal_hemorrhage | 0.93236462 |
| 61 | MP0002998_abnormal_bone_remodeling | 0.92734694 |
| 62 | MP0001851_eye_inflammation | 0.87915691 |
| 63 | MP0001764_abnormal_homeostasis | 0.86827397 |
| 64 | MP0003806_abnormal_nucleotide_metabolis | 0.86334414 |
| 65 | MP0001348_abnormal_lacrimal_gland | 0.84890786 |
| 66 | MP0003448_altered_tumor_morphology | 0.84559267 |
| 67 | MP0004142_abnormal_muscle_tone | 0.83519586 |
| 68 | MP0009763_increased_sensitivity_to | 0.78186494 |
| 69 | MP0002693_abnormal_pancreas_physiology | 0.75850435 |
| 70 | MP0003183_abnormal_peptide_metabolism | 0.75733925 |
| 71 | MP0005379_endocrine/exocrine_gland_phen | 0.73518602 |
| 72 | MP0001986_abnormal_taste_sensitivity | 0.72704774 |
| 73 | MP0003172_abnormal_lysosome_physiology | 0.67457163 |
| 74 | MP0005381_digestive/alimentary_phenotyp | 0.64370953 |
| 75 | MP0001919_abnormal_reproductive_system | 0.64043892 |
| 76 | MP0002019_abnormal_tumor_incidence | 0.61456537 |
| 77 | MP0003786_premature_aging | 0.60968923 |
| 78 | MP0005390_skeleton_phenotype | 0.60754155 |
| 79 | MP0005409_darkened_coat_color | 0.58087431 |
| 80 | MP0005377_hearing/vestibular/ear_phenot | 0.57870082 |
| 81 | MP0003878_abnormal_ear_physiology | 0.57870082 |
| 82 | MP0004036_abnormal_muscle_relaxation | 0.57581823 |
| 83 | MP0000490_abnormal_crypts_of | 0.56471506 |
| 84 | MP0001502_abnormal_circadian_rhythm | 0.53162442 |
| 85 | MP0002837_dystrophic_cardiac_calcinosis | 0.52565049 |
| 86 | MP0000569_abnormal_digit_pigmentation | 0.51091754 |
| 87 | MP0005376_homeostasis/metabolism_phenot | 0.50240952 |
| 88 | MP0003795_abnormal_bone_structure | 0.50147810 |
| 89 | MP0004130_abnormal_muscle_cell | 0.49886284 |
| 90 | MP0004510_myositis | 0.49762853 |
| 91 | MP0005266_abnormal_metabolism | 0.46317252 |
| 92 | MP0008260_abnormal_autophagy | 0.46090324 |
| 93 | MP0005166_decreased_susceptibility_to | 0.45680208 |
| 94 | MP0009765_abnormal_xenobiotic_induced | 0.43990498 |
| 95 | MP0002332_abnormal_exercise_endurance | 0.43495833 |
| 96 | MP0001765_abnormal_ion_homeostasis | 0.40692807 |
| 97 | MP0002136_abnormal_kidney_physiology | 0.40684801 |
| 98 | MP0000249_abnormal_blood_vessel | 0.38742404 |
| 99 | MP0000470_abnormal_stomach_morphology | 0.38718410 |
| 100 | MP0008872_abnormal_physiological_respon | 0.36740442 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 7.58358574 |
| 2 | Stomatitis (HP:0010280) | 6.70545069 |
| 3 | T lymphocytopenia (HP:0005403) | 5.91551140 |
| 4 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 5.47352326 |
| 5 | Abnormality of T cell number (HP:0011839) | 5.45483964 |
| 6 | Autoimmune hemolytic anemia (HP:0001890) | 5.34266157 |
| 7 | IgG deficiency (HP:0004315) | 5.16160998 |
| 8 | Eczematoid dermatitis (HP:0000976) | 4.85817249 |
| 9 | Abnormality of T cells (HP:0002843) | 4.80930634 |
| 10 | Recurrent cutaneous fungal infections (HP:0011370) | 4.67296038 |
| 11 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.67296038 |
| 12 | Panhypogammaglobulinemia (HP:0003139) | 4.42350330 |
| 13 | Recurrent fungal infections (HP:0002841) | 4.38575179 |
| 14 | Aplastic anemia (HP:0001915) | 4.35232438 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 4.10297377 |
| 16 | Encephalitis (HP:0002383) | 3.94531081 |
| 17 | IgM deficiency (HP:0002850) | 3.79883775 |
| 18 | Myositis (HP:0100614) | 3.77555038 |
| 19 | Meningitis (HP:0001287) | 3.75419170 |
| 20 | Increased IgM level (HP:0003496) | 3.74787467 |
| 21 | Abnormality of macrophages (HP:0004311) | 3.67851874 |
| 22 | Vasculitis (HP:0002633) | 3.67149891 |
| 23 | Chronic diarrhea (HP:0002028) | 3.63750557 |
| 24 | Hypoplasia of the thymus (HP:0000778) | 3.63747419 |
| 25 | Gastrointestinal infarctions (HP:0005244) | 3.61895302 |
| 26 | Abnormality of T cell physiology (HP:0011840) | 3.54197730 |
| 27 | Recurrent bronchitis (HP:0002837) | 3.53201469 |
| 28 | Pustule (HP:0200039) | 3.49731953 |
| 29 | Increased IgE level (HP:0003212) | 3.37358201 |
| 30 | Retrobulbar optic neuritis (HP:0100654) | 3.35745394 |
| 31 | Optic neuritis (HP:0100653) | 3.35745394 |
| 32 | Abnormality of eosinophils (HP:0001879) | 3.35487491 |
| 33 | Pulmonary infiltrates (HP:0002113) | 3.34371832 |
| 34 | Obstructive lung disease (HP:0006536) | 3.30497203 |
| 35 | Chronic obstructive pulmonary disease (HP:0006510) | 3.30497203 |
| 36 | Leukocytosis (HP:0001974) | 3.27115500 |
| 37 | Orchitis (HP:0100796) | 3.25783783 |
| 38 | Lymphopenia (HP:0001888) | 3.25175246 |
| 39 | Agammaglobulinemia (HP:0004432) | 3.24528104 |
| 40 | Recurrent skin infections (HP:0001581) | 3.21712557 |
| 41 | Spontaneous hematomas (HP:0007420) | 3.19147661 |
| 42 | Combined immunodeficiency (HP:0005387) | 3.17146314 |
| 43 | Recurrent bacterial skin infections (HP:0005406) | 3.16047050 |
| 44 | Joint swelling (HP:0001386) | 3.10742888 |
| 45 | Recurrent viral infections (HP:0004429) | 3.08118630 |
| 46 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.01028490 |
| 47 | Recurrent abscess formation (HP:0002722) | 3.00052204 |
| 48 | Mediastinal lymphadenopathy (HP:0100721) | 2.98183868 |
| 49 | Thyroiditis (HP:0100646) | 2.97055844 |
| 50 | Eosinophilia (HP:0001880) | 2.84251330 |
| 51 | Chest pain (HP:0100749) | 2.83923926 |
| 52 | Granulocytopenia (HP:0001913) | 2.76463595 |
| 53 | Hemoptysis (HP:0002105) | 2.72755658 |
| 54 | Lymphoma (HP:0002665) | 2.68247728 |
| 55 | Pulmonary embolism (HP:0002204) | 2.67112439 |
| 56 | Petechiae (HP:0000967) | 2.66416608 |
| 57 | Hypergammaglobulinemia (HP:0010702) | 2.60864338 |
| 58 | Keratoconjunctivitis sicca (HP:0001097) | 2.59166295 |
| 59 | Cutaneous melanoma (HP:0012056) | 2.53745210 |
| 60 | Hypochromic anemia (HP:0001931) | 2.44350639 |
| 61 | Microcytic anemia (HP:0001935) | 2.43420660 |
| 62 | Hypochromic microcytic anemia (HP:0004840) | 2.41493097 |
| 63 | Abnormality of the prostate (HP:0008775) | 2.41356010 |
| 64 | Inflammation of the large intestine (HP:0002037) | 2.37596629 |
| 65 | Keratoconjunctivitis (HP:0001096) | 2.36511613 |
| 66 | Glomerulopathy (HP:0100820) | 2.32761615 |
| 67 | Gastrointestinal inflammation (HP:0004386) | 2.29139892 |
| 68 | Skin rash (HP:0000988) | 2.28335286 |
| 69 | Gangrene (HP:0100758) | 2.28272997 |
| 70 | Papilledema (HP:0001085) | 2.25627881 |
| 71 | Ureteral stenosis (HP:0000071) | 2.25385142 |
| 72 | Basal ganglia calcification (HP:0002135) | 2.23514539 |
| 73 | Abnormality of the fingertips (HP:0001211) | 2.20476022 |
| 74 | Abnormality of the pleura (HP:0002103) | 2.19111757 |
| 75 | Epistaxis (HP:0000421) | 2.18372794 |
| 76 | Urticaria (HP:0001025) | 2.17712946 |
| 77 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.15392334 |
| 78 | Ureteral obstruction (HP:0006000) | 2.14121807 |
| 79 | Hypoproteinemia (HP:0003075) | 2.12832496 |
| 80 | Prolonged bleeding time (HP:0003010) | 2.10912922 |
| 81 | Abnormality of the pericardium (HP:0001697) | 2.08813971 |
| 82 | Acute hepatic failure (HP:0006554) | 2.07981112 |
| 83 | Purpura (HP:0000979) | 2.06939596 |
| 84 | Bronchitis (HP:0012387) | 2.05449454 |
| 85 | Stomach cancer (HP:0012126) | 2.05000612 |
| 86 | Abnormality of B cell number (HP:0010975) | 2.03702590 |
| 87 | Anomalous pulmonary venous return (HP:0010772) | 2.03630194 |
| 88 | Restrictive lung disease (HP:0002091) | 2.02278291 |
| 89 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.98905387 |
| 90 | Colitis (HP:0002583) | 1.98540872 |
| 91 | Episodic fever (HP:0001954) | 1.97079389 |
| 92 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.93333502 |
| 93 | Sepsis (HP:0100806) | 1.93259847 |
| 94 | Chronic otitis media (HP:0000389) | 1.92312070 |
| 95 | Alveolar cell carcinoma (HP:0006519) | 1.88548279 |
| 96 | Basal cell carcinoma (HP:0002671) | 1.88375295 |
| 97 | Pancytopenia (HP:0001876) | 1.87273867 |
| 98 | Hyperlipoproteinemia (HP:0010980) | 1.86976464 |
| 99 | Arterial thrombosis (HP:0004420) | 1.86774020 |
| 100 | Gingivitis (HP:0000230) | 1.85958408 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 7.50275064 |
| 2 | MAP4K1 | 4.79420739 |
| 3 | ITK | 3.01829042 |
| 4 | SIK3 | 2.98596931 |
| 5 | FGFR4 | 2.91036262 |
| 6 | ZAP70 | 2.79848029 |
| 7 | FES | 2.60089733 |
| 8 | EPHA3 | 2.53650071 |
| 9 | JAK3 | 2.47562098 |
| 10 | NLK | 2.35294140 |
| 11 | EPHB1 | 2.31223019 |
| 12 | IRAK4 | 2.20542695 |
| 13 | CSK | 2.20541021 |
| 14 | BTK | 2.11126916 |
| 15 | TYK2 | 2.04632725 |
| 16 | RIPK4 | 1.85563660 |
| 17 | LCK | 1.80644839 |
| 18 | FGFR3 | 1.79429318 |
| 19 | TEC | 1.79389441 |
| 20 | JAK1 | 1.73798265 |
| 21 | SIK2 | 1.70653833 |
| 22 | TNK2 | 1.67930587 |
| 23 | SYK | 1.66511212 |
| 24 | HCK | 1.62252680 |
| 25 | MAP3K11 | 1.54580680 |
| 26 | IKBKE | 1.47830542 |
| 27 | PASK | 1.40544902 |
| 28 | MAP2K3 | 1.35190110 |
| 29 | MARK3 | 1.33978069 |
| 30 | SIK1 | 1.33803778 |
| 31 | GRK6 | 1.30768623 |
| 32 | PRPF4B | 1.29512394 |
| 33 | MAP3K3 | 1.29402181 |
| 34 | MST4 | 1.23694003 |
| 35 | BLK | 1.17100609 |
| 36 | TAOK3 | 1.15836332 |
| 37 | IRAK1 | 1.10313224 |
| 38 | LYN | 1.09284142 |
| 39 | PRKCQ | 1.04507312 |
| 40 | IKBKB | 1.03538830 |
| 41 | KDR | 0.98481103 |
| 42 | TYRO3 | 0.93554867 |
| 43 | TESK2 | 0.90488732 |
| 44 | FGFR2 | 0.87758637 |
| 45 | JAK2 | 0.87565947 |
| 46 | FGR | 0.78620752 |
| 47 | MAP3K14 | 0.76293684 |
| 48 | MAPK12 | 0.76125581 |
| 49 | CAMKK1 | 0.74653712 |
| 50 | SGK3 | 0.74590677 |
| 51 | PDGFRB | 0.74376545 |
| 52 | CAMKK2 | 0.74279228 |
| 53 | HIPK2 | 0.73944181 |
| 54 | STK38L | 0.72287439 |
| 55 | TBK1 | 0.72029744 |
| 56 | FYN | 0.67204719 |
| 57 | ERN1 | 0.65123486 |
| 58 | STK38 | 0.63567815 |
| 59 | ADRBK2 | 0.60498696 |
| 60 | MAPK11 | 0.59896500 |
| 61 | KIT | 0.59656359 |
| 62 | MAP3K1 | 0.58729611 |
| 63 | MAP3K13 | 0.56689013 |
| 64 | SGK2 | 0.56069670 |
| 65 | CDK19 | 0.55897918 |
| 66 | CSF1R | 0.49047461 |
| 67 | MELK | 0.48988318 |
| 68 | AKT3 | 0.45102784 |
| 69 | STK10 | 0.44906003 |
| 70 | CLK1 | 0.44883305 |
| 71 | PIM1 | 0.44839770 |
| 72 | RET | 0.44402177 |
| 73 | MAP3K10 | 0.44166687 |
| 74 | CHUK | 0.43623498 |
| 75 | IGF1R | 0.36469167 |
| 76 | GRK7 | 0.35884461 |
| 77 | RPS6KA5 | 0.34318914 |
| 78 | TAOK1 | 0.34311390 |
| 79 | SGK494 | 0.32685782 |
| 80 | SGK223 | 0.32685782 |
| 81 | CAMK4 | 0.32095585 |
| 82 | ALK | 0.31980457 |
| 83 | SCYL2 | 0.31421286 |
| 84 | TAOK2 | 0.30826435 |
| 85 | STK24 | 0.30752727 |
| 86 | MAPKAPK2 | 0.30152116 |
| 87 | PDK1 | 0.29086318 |
| 88 | CDK4 | 0.27357338 |
| 89 | PRKCH | 0.25246515 |
| 90 | RPS6KA4 | 0.24628245 |
| 91 | INSR | 0.23124968 |
| 92 | MAP2K6 | 0.22042883 |
| 93 | MARK2 | 0.21122097 |
| 94 | LRRK2 | 0.19330258 |
| 95 | PRKCD | 0.17504160 |
| 96 | MAPK3 | 0.16712782 |
| 97 | NTRK2 | 0.16653653 |
| 98 | NUAK1 | 0.16498811 |
| 99 | SMG1 | 0.14467948 |
| 100 | EGFR | 0.12911014 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.36781280 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.69633870 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.54421308 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.26855748 |
| 5 | Measles_Homo sapiens_hsa05162 | 3.09972158 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.09164142 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.99513178 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.80859592 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.64992915 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.49537345 |
| 11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.44619202 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.05472525 |
| 13 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.05378260 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.84164002 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.79778385 |
| 16 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.73547998 |
| 17 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.69283210 |
| 18 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.62799995 |
| 19 | Viral myocarditis_Homo sapiens_hsa05416 | 1.60727524 |
| 20 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.58326687 |
| 21 | Leishmaniasis_Homo sapiens_hsa05140 | 1.57468734 |
| 22 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.54107978 |
| 23 | Malaria_Homo sapiens_hsa05144 | 1.49844629 |
| 24 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.46337906 |
| 25 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.41080836 |
| 26 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.35416656 |
| 27 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.34618134 |
| 28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.28528915 |
| 29 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.27120674 |
| 30 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.24963495 |
| 31 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.18203381 |
| 32 | Asthma_Homo sapiens_hsa05310 | 1.17639746 |
| 33 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.17342193 |
| 34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.15053874 |
| 35 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.12166105 |
| 36 | Shigellosis_Homo sapiens_hsa05131 | 1.09932383 |
| 37 | Influenza A_Homo sapiens_hsa05164 | 1.04337447 |
| 38 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.00042877 |
| 39 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.97493777 |
| 40 | HTLV-I infection_Homo sapiens_hsa05166 | 0.94585054 |
| 41 | Platelet activation_Homo sapiens_hsa04611 | 0.94567267 |
| 42 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.92771590 |
| 43 | Tuberculosis_Homo sapiens_hsa05152 | 0.92704540 |
| 44 | Hepatitis B_Homo sapiens_hsa05161 | 0.92065001 |
| 45 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.89889506 |
| 46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.86953175 |
| 47 | Apoptosis_Homo sapiens_hsa04210 | 0.84013460 |
| 48 | Hepatitis C_Homo sapiens_hsa05160 | 0.81143195 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.80949913 |
| 50 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72240447 |
| 51 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.68256781 |
| 52 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.66642776 |
| 53 | Basal transcription factors_Homo sapiens_hsa03022 | 0.65018519 |
| 54 | Salmonella infection_Homo sapiens_hsa05132 | 0.63513631 |
| 55 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.63446071 |
| 56 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.63144522 |
| 57 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.62519598 |
| 58 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.62293533 |
| 59 | Legionellosis_Homo sapiens_hsa05134 | 0.61175749 |
| 60 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.59249473 |
| 61 | Insulin resistance_Homo sapiens_hsa04931 | 0.59153910 |
| 62 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59103438 |
| 63 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.58714673 |
| 64 | Endocytosis_Homo sapiens_hsa04144 | 0.57552212 |
| 65 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.48158757 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46356953 |
| 67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.46099660 |
| 68 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.45820798 |
| 69 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.45044708 |
| 70 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.44901122 |
| 71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44472308 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.42679052 |
| 73 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.38041644 |
| 74 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.37588629 |
| 75 | Pertussis_Homo sapiens_hsa05133 | 0.37247107 |
| 76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.37119916 |
| 77 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.36003262 |
| 78 | Phototransduction_Homo sapiens_hsa04744 | 0.33875528 |
| 79 | Ribosome_Homo sapiens_hsa03010 | 0.32969797 |
| 80 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.32578051 |
| 81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.32567568 |
| 82 | Phagosome_Homo sapiens_hsa04145 | 0.30434305 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.29568488 |
| 84 | Thyroid cancer_Homo sapiens_hsa05216 | 0.29430910 |
| 85 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.26702837 |
| 86 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.25886267 |
| 87 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.24417660 |
| 88 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.24279260 |
| 89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.24142570 |
| 90 | Colorectal cancer_Homo sapiens_hsa05210 | 0.22668954 |
| 91 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22009151 |
| 92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.21499582 |
| 93 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.19992686 |
| 94 | Morphine addiction_Homo sapiens_hsa05032 | 0.19927880 |
| 95 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.19758965 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.19729820 |
| 97 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.19350258 |
| 98 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.18977293 |
| 99 | Long-term potentiation_Homo sapiens_hsa04720 | 0.18624126 |
| 100 | Proteasome_Homo sapiens_hsa03050 | 0.18255615 |

