

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of isotype switching to IgG isotypes (GO:0048302) | 9.53794229 |
| 2 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 9.07214283 |
| 3 | positive regulation of isotype switching (GO:0045830) | 8.29393326 |
| 4 | regulation of chronic inflammatory response (GO:0002676) | 7.92196122 |
| 5 | positive regulation of granulocyte differentiation (GO:0030854) | 7.63177033 |
| 6 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 7.47103247 |
| 7 | negative regulation of T-helper cell differentiation (GO:0045623) | 7.47103247 |
| 8 | regulation of podosome assembly (GO:0071801) | 7.25422368 |
| 9 | positive regulation of immunoglobulin production (GO:0002639) | 7.24292152 |
| 10 | positive regulation of DNA recombination (GO:0045911) | 7.21243599 |
| 11 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 6.78279722 |
| 12 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 6.30613892 |
| 13 | T-helper cell differentiation (GO:0042093) | 6.30613892 |
| 14 | cytokine production involved in immune response (GO:0002367) | 6.13199052 |
| 15 | regulation of isotype switching (GO:0045191) | 5.98145214 |
| 16 | negative T cell selection (GO:0043383) | 5.77581154 |
| 17 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 5.74926435 |
| 18 | alpha-beta T cell activation involved in immune response (GO:0002287) | 5.74926435 |
| 19 | T cell differentiation involved in immune response (GO:0002292) | 5.74926435 |
| 20 | regulation of interleukin-13 production (GO:0032656) | 5.72785317 |
| 21 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 5.70736344 |
| 22 | regulation of immunoglobulin secretion (GO:0051023) | 5.70373482 |
| 23 | T cell lineage commitment (GO:0002360) | 5.63267492 |
| 24 | regulation of immunoglobulin production (GO:0002637) | 5.58118824 |
| 25 | positive regulation of chemokine biosynthetic process (GO:0045080) | 5.55731600 |
| 26 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.37019815 |
| 27 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 5.32851133 |
| 28 | positive regulation of B cell mediated immunity (GO:0002714) | 5.32851133 |
| 29 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 5.29468597 |
| 30 | cytidine metabolic process (GO:0046087) | 5.22568292 |
| 31 | cytidine catabolic process (GO:0006216) | 5.22568292 |
| 32 | cytidine deamination (GO:0009972) | 5.22568292 |
| 33 | negative regulation of alpha-beta T cell activation (GO:0046636) | 5.18816105 |
| 34 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 5.13891057 |
| 35 | regulation of MHC class II biosynthetic process (GO:0045346) | 5.13493911 |
| 36 | cellular response to interferon-beta (GO:0035458) | 5.09898887 |
| 37 | regulation of granulocyte differentiation (GO:0030852) | 5.06956076 |
| 38 | response to mercury ion (GO:0046689) | 5.04703671 |
| 39 | cellular response to interleukin-15 (GO:0071350) | 4.93869925 |
| 40 | negative regulation of acute inflammatory response (GO:0002674) | 4.89300634 |
| 41 | positive T cell selection (GO:0043368) | 4.85343907 |
| 42 | cytokine biosynthetic process (GO:0042089) | 4.84720719 |
| 43 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.84362241 |
| 44 | defense response to protozoan (GO:0042832) | 4.79923654 |
| 45 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.70999078 |
| 46 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 4.63037741 |
| 47 | response to interleukin-15 (GO:0070672) | 4.60471001 |
| 48 | T cell mediated immunity (GO:0002456) | 4.54497394 |
| 49 | alpha-beta T cell differentiation (GO:0046632) | 4.41038587 |
| 50 | DNA deamination (GO:0045006) | 4.39767228 |
| 51 | activated T cell proliferation (GO:0050798) | 4.37581236 |
| 52 | regulation of proton transport (GO:0010155) | 4.30435178 |
| 53 | regulation of chemokine biosynthetic process (GO:0045073) | 4.30430741 |
| 54 | cellular defense response (GO:0006968) | 4.29944647 |
| 55 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.26060820 |
| 56 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.24580237 |
| 57 | positive regulation of B cell proliferation (GO:0030890) | 4.20962980 |
| 58 | response to protozoan (GO:0001562) | 4.14522842 |
| 59 | negative thymic T cell selection (GO:0045060) | 4.12645005 |
| 60 | positive regulation of interleukin-10 production (GO:0032733) | 4.10074941 |
| 61 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.05334596 |
| 62 | production of molecular mediator of immune response (GO:0002440) | 4.05282312 |
| 63 | cytokine metabolic process (GO:0042107) | 4.02577893 |
| 64 | response to interferon-beta (GO:0035456) | 4.02420856 |
| 65 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.97203130 |
| 66 | T cell selection (GO:0045058) | 3.96468906 |
| 67 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.95152309 |
| 68 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.95068676 |
| 69 | positive regulation of defense response to virus by host (GO:0002230) | 3.91705962 |
| 70 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.91078713 |
| 71 | positive regulation of B cell activation (GO:0050871) | 3.86452009 |
| 72 | regulation of B cell mediated immunity (GO:0002712) | 3.83682943 |
| 73 | positive regulation of production of molecular mediator of immune response (GO:0002702) | 3.83252463 |
| 74 | alpha-beta T cell activation (GO:0046631) | 3.76968691 |
| 75 | negative regulation of adaptive immune response (GO:0002820) | 3.69775038 |
| 76 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.67542304 |
| 77 | regulation of macrophage activation (GO:0043030) | 3.62585475 |
| 78 | regulation of B cell proliferation (GO:0030888) | 3.56646090 |
| 79 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.41622818 |
| 80 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.36376257 |
| 81 | negative regulation of cell killing (GO:0031342) | 3.34496103 |
| 82 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.34496103 |
| 83 | interferon-gamma production (GO:0032609) | 3.34280275 |
| 84 | hepatocyte apoptotic process (GO:0097284) | 3.29066114 |
| 85 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.28290244 |
| 86 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.22368680 |
| 87 | innate immune response in mucosa (GO:0002227) | 3.19839755 |
| 88 | regulation of B cell activation (GO:0050864) | 3.16926033 |
| 89 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.15583896 |
| 90 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.15153142 |
| 91 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.13612318 |
| 92 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.13463707 |
| 93 | negative regulation of T cell mediated immunity (GO:0002710) | 3.13366972 |
| 94 | negative regulation of interleukin-12 production (GO:0032695) | 3.09088912 |
| 95 | thymic T cell selection (GO:0045061) | 3.07128725 |
| 96 | negative regulation of T cell differentiation (GO:0045581) | 3.05666958 |
| 97 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.04720044 |
| 98 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.04686770 |
| 99 | regulation of T-helper cell differentiation (GO:0045622) | 3.03943756 |
| 100 | positive regulation of leukocyte mediated immunity (GO:0002705) | 3.03440577 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.89140370 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.02770776 |
| 3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 4.65313898 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.24478050 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.29898713 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.29541966 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.19580046 |
| 8 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.14718643 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.13228611 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.12436755 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.05651354 |
| 12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.75119799 |
| 13 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.60305247 |
| 14 | GATA3_26560356_Chip-Seq_TH2_Human | 2.57930779 |
| 15 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.48126283 |
| 16 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.46405259 |
| 17 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.35485928 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.17232148 |
| 19 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.14839980 |
| 20 | MAF_26560356_Chip-Seq_TH1_Human | 1.94545484 |
| 21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.93882228 |
| 22 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.93213675 |
| 23 | MYB_26560356_Chip-Seq_TH1_Human | 1.91571009 |
| 24 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.85713470 |
| 25 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.82194144 |
| 26 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.75046474 |
| 27 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.71178133 |
| 28 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.69860805 |
| 29 | MAF_26560356_Chip-Seq_TH2_Human | 1.63190743 |
| 30 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.61081499 |
| 31 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.60880067 |
| 32 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.52654653 |
| 33 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52531871 |
| 34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.48008332 |
| 35 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.46657304 |
| 36 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.45341820 |
| 37 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.41755835 |
| 38 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.38713186 |
| 39 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.38032570 |
| 40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.37256936 |
| 41 | UTX_26944678_Chip-Seq_JUKART_Human | 1.36639740 |
| 42 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.35628218 |
| 43 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35206946 |
| 44 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.34195573 |
| 45 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.32994451 |
| 46 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.30814467 |
| 47 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.29735673 |
| 48 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.28532662 |
| 49 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.27139642 |
| 50 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.23552654 |
| 51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.22723636 |
| 52 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.22533301 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.20769323 |
| 54 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.20101511 |
| 55 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.19922649 |
| 56 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.19007060 |
| 57 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.18896559 |
| 58 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.17589188 |
| 59 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14205029 |
| 60 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11659473 |
| 61 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10079482 |
| 62 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.08044346 |
| 63 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.07806111 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.04276335 |
| 65 | VDR_22108803_ChIP-Seq_LS180_Human | 1.03903508 |
| 66 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03244202 |
| 67 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.03137083 |
| 68 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.02425971 |
| 69 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.01356671 |
| 70 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.99877255 |
| 71 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.99134021 |
| 72 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.98750337 |
| 73 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.98059227 |
| 74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97236687 |
| 75 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.97166946 |
| 76 | GATA3_26560356_Chip-Seq_TH1_Human | 0.97157819 |
| 77 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.97007166 |
| 78 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96275589 |
| 79 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.95637072 |
| 80 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.92501901 |
| 81 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.90694216 |
| 82 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.90558865 |
| 83 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89868827 |
| 84 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.89761470 |
| 85 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.89335867 |
| 86 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88915765 |
| 87 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.88063707 |
| 88 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.87365135 |
| 89 | SPI1_23127762_ChIP-Seq_K562_Human | 0.86931253 |
| 90 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85729834 |
| 91 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.85711005 |
| 92 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.84493400 |
| 93 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.84024189 |
| 94 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.83506508 |
| 95 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.83237101 |
| 96 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80378306 |
| 97 | ERA_21632823_ChIP-Seq_H3396_Human | 0.79968188 |
| 98 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.78277508 |
| 99 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.75154777 |
| 100 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.74197309 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001348_abnormal_lacrimal_gland | 6.42681208 |
| 2 | MP0001873_stomach_inflammation | 5.78350201 |
| 3 | MP0008057_abnormal_DNA_replication | 4.54904231 |
| 4 | MP0005671_abnormal_response_to | 4.45136741 |
| 5 | MP0003763_abnormal_thymus_physiology | 4.34123702 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.96634099 |
| 7 | MP0006082_CNS_inflammation | 3.92490493 |
| 8 | MP0000685_abnormal_immune_system | 3.27344568 |
| 9 | MP0001790_abnormal_immune_system | 3.12522246 |
| 10 | MP0005387_immune_system_phenotype | 3.12522246 |
| 11 | MP0005310_abnormal_salivary_gland | 2.63950873 |
| 12 | MP0001800_abnormal_humoral_immune | 2.49123119 |
| 13 | MP0009333_abnormal_splenocyte_physiolog | 2.47967321 |
| 14 | MP0001853_heart_inflammation | 2.39588579 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.39223093 |
| 16 | MP0005000_abnormal_immune_tolerance | 2.18963471 |
| 17 | MP0003866_abnormal_defecation | 2.04363133 |
| 18 | MP0008872_abnormal_physiological_respon | 2.02622917 |
| 19 | MP0005025_abnormal_response_to | 2.01092829 |
| 20 | MP0002166_altered_tumor_susceptibility | 1.99113010 |
| 21 | MP0003436_decreased_susceptibility_to | 1.98556768 |
| 22 | MP0003191_abnormal_cellular_cholesterol | 1.93911788 |
| 23 | MP0009840_abnormal_foam_cell | 1.93138447 |
| 24 | MP0002723_abnormal_immune_serum | 1.92259889 |
| 25 | MP0002420_abnormal_adaptive_immunity | 1.73959342 |
| 26 | MP0001819_abnormal_immune_cell | 1.69312550 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.66483157 |
| 28 | MP0005377_hearing/vestibular/ear_phenot | 1.62083620 |
| 29 | MP0003878_abnormal_ear_physiology | 1.62083620 |
| 30 | MP0000703_abnormal_thymus_morphology | 1.62011703 |
| 31 | MP0002452_abnormal_antigen_presenting | 1.58905565 |
| 32 | MP0009278_abnormal_bone_marrow | 1.54603697 |
| 33 | MP0003300_gastrointestinal_ulcer | 1.52939966 |
| 34 | MP0004084_abnormal_cardiac_muscle | 1.51892879 |
| 35 | MP0002653_abnormal_ependyma_morphology | 1.49723057 |
| 36 | MP0002148_abnormal_hypersensitivity_rea | 1.47740010 |
| 37 | MP0003045_fibrosis | 1.46711196 |
| 38 | MP0000716_abnormal_immune_system | 1.43819844 |
| 39 | MP0002009_preneoplasia | 1.39303157 |
| 40 | MP0001663_abnormal_digestive_system | 1.37763796 |
| 41 | MP0004036_abnormal_muscle_relaxation | 1.37353935 |
| 42 | MP0002398_abnormal_bone_marrow | 1.35289118 |
| 43 | MP0002138_abnormal_hepatobiliary_system | 1.34328482 |
| 44 | MP0002006_tumorigenesis | 1.34147651 |
| 45 | MP0009785_altered_susceptibility_to | 1.30105723 |
| 46 | MP0010155_abnormal_intestine_physiology | 1.30073205 |
| 47 | MP0002419_abnormal_innate_immunity | 1.29906507 |
| 48 | MP0002405_respiratory_system_inflammati | 1.26238413 |
| 49 | MP0000689_abnormal_spleen_morphology | 1.17434467 |
| 50 | MP0002722_abnormal_immune_system | 1.17352166 |
| 51 | MP0008469_abnormal_protein_level | 1.13772532 |
| 52 | MP0002429_abnormal_blood_cell | 1.11895221 |
| 53 | MP0004142_abnormal_muscle_tone | 1.11268653 |
| 54 | MP0004381_abnormal_hair_follicle | 1.09593222 |
| 55 | MP0002277_abnormal_respiratory_mucosa | 1.07101167 |
| 56 | MP0008775_abnormal_heart_ventricle | 1.03620976 |
| 57 | MP0000858_altered_metastatic_potential | 1.01105461 |
| 58 | MP0001845_abnormal_inflammatory_respons | 1.00082665 |
| 59 | MP0010352_gastrointestinal_tract_polyps | 0.94682570 |
| 60 | MP0002736_abnormal_nociception_after | 0.86060957 |
| 61 | MP0005381_digestive/alimentary_phenotyp | 0.85733196 |
| 62 | MP0001533_abnormal_skeleton_physiology | 0.85333761 |
| 63 | MP0001765_abnormal_ion_homeostasis | 0.84990512 |
| 64 | MP0002693_abnormal_pancreas_physiology | 0.81311485 |
| 65 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.79482841 |
| 66 | MP0005319_abnormal_enzyme/_coenzyme | 0.79323818 |
| 67 | MP0001968_abnormal_touch/_nociception | 0.76925053 |
| 68 | MP0003303_peritoneal_inflammation | 0.76783052 |
| 69 | MP0005464_abnormal_platelet_physiology | 0.74922637 |
| 70 | MP0002998_abnormal_bone_remodeling | 0.74529148 |
| 71 | MP0002163_abnormal_gland_morphology | 0.74079889 |
| 72 | MP0009763_increased_sensitivity_to | 0.72810827 |
| 73 | MP0005166_decreased_susceptibility_to | 0.72770357 |
| 74 | MP0003448_altered_tumor_morphology | 0.72612565 |
| 75 | MP0003880_abnormal_central_pattern | 0.71038838 |
| 76 | MP0003646_muscle_fatigue | 0.67260017 |
| 77 | MP0003959_abnormal_lean_body | 0.65408982 |
| 78 | MP0005379_endocrine/exocrine_gland_phen | 0.63190305 |
| 79 | MP0002933_joint_inflammation | 0.61796380 |
| 80 | MP0000477_abnormal_intestine_morphology | 0.61366068 |
| 81 | MP0005448_abnormal_energy_balance | 0.59156914 |
| 82 | MP0001986_abnormal_taste_sensitivity | 0.57917406 |
| 83 | MP0005167_abnormal_blood-brain_barrier | 0.55953243 |
| 84 | MP0005075_abnormal_melanosome_morpholog | 0.55858478 |
| 85 | MP0004947_skin_inflammation | 0.54721237 |
| 86 | MP0003186_abnormal_redox_activity | 0.53703506 |
| 87 | MP0009764_decreased_sensitivity_to | 0.51266462 |
| 88 | MP0003724_increased_susceptibility_to | 0.51217741 |
| 89 | MP0002019_abnormal_tumor_incidence | 0.51060790 |
| 90 | MP0005636_abnormal_mineral_homeostasis | 0.50527885 |
| 91 | MP0004215_abnormal_myocardial_fiber | 0.48313893 |
| 92 | MP0009765_abnormal_xenobiotic_induced | 0.47675270 |
| 93 | MP0005266_abnormal_metabolism | 0.46901990 |
| 94 | MP0000569_abnormal_digit_pigmentation | 0.46498882 |
| 95 | MP0002168_other_aberrant_phenotype | 0.43048901 |
| 96 | MP0002254_reproductive_system_inflammat | 0.42912342 |
| 97 | MP0004742_abnormal_vestibular_system | 0.42576299 |
| 98 | MP0003786_premature_aging | 0.42505649 |
| 99 | MP0008873_increased_physiological_sensi | 0.41703420 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.40220918 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.98975194 |
| 2 | Chronic mucocutaneous candidiasis (HP:0002728) | 5.62137857 |
| 3 | Recurrent cutaneous fungal infections (HP:0011370) | 5.62137857 |
| 4 | Stomatitis (HP:0010280) | 5.60174490 |
| 5 | T lymphocytopenia (HP:0005403) | 5.36292052 |
| 6 | IgG deficiency (HP:0004315) | 4.79453334 |
| 7 | Abnormality of T cell number (HP:0011839) | 4.75630752 |
| 8 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.67770357 |
| 9 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 4.61943098 |
| 10 | Severe combined immunodeficiency (HP:0004430) | 4.54181521 |
| 11 | Agammaglobulinemia (HP:0004432) | 4.49539471 |
| 12 | Recurrent fungal infections (HP:0002841) | 4.48650606 |
| 13 | Abnormality of T cells (HP:0002843) | 4.43880491 |
| 14 | Eczematoid dermatitis (HP:0000976) | 4.42698254 |
| 15 | Panhypogammaglobulinemia (HP:0003139) | 4.36450390 |
| 16 | Recurrent bronchitis (HP:0002837) | 3.78941449 |
| 17 | Abnormality of eosinophils (HP:0001879) | 3.76233735 |
| 18 | Increased IgE level (HP:0003212) | 3.55930168 |
| 19 | Combined immunodeficiency (HP:0005387) | 3.51666166 |
| 20 | Thyroiditis (HP:0100646) | 3.51217742 |
| 21 | Chronic diarrhea (HP:0002028) | 3.50779127 |
| 22 | Hypoplasia of the thymus (HP:0000778) | 3.47342184 |
| 23 | Pigmentary retinal degeneration (HP:0001146) | 3.32154657 |
| 24 | Leukocytosis (HP:0001974) | 3.30250121 |
| 25 | Large for gestational age (HP:0001520) | 3.23882966 |
| 26 | Pustule (HP:0200039) | 3.20058817 |
| 27 | Aplastic anemia (HP:0001915) | 3.19597509 |
| 28 | Fatigue (HP:0012378) | 3.10459349 |
| 29 | Colitis (HP:0002583) | 3.08584092 |
| 30 | Petechiae (HP:0000967) | 3.05366418 |
| 31 | Recurrent skin infections (HP:0001581) | 2.95719287 |
| 32 | Encephalitis (HP:0002383) | 2.92122058 |
| 33 | Abnormality of T cell physiology (HP:0011840) | 2.88548759 |
| 34 | J-shaped sella turcica (HP:0002680) | 2.85323954 |
| 35 | Eosinophilia (HP:0001880) | 2.81750310 |
| 36 | Central scotoma (HP:0000603) | 2.78156236 |
| 37 | Increased hepatocellular lipid droplets (HP:0006565) | 2.67092702 |
| 38 | Pulmonary infiltrates (HP:0002113) | 2.53715297 |
| 39 | Recurrent viral infections (HP:0004429) | 2.52564097 |
| 40 | Inflammation of the large intestine (HP:0002037) | 2.51782962 |
| 41 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.50371957 |
| 42 | Hypoplasia of the fovea (HP:0007750) | 2.50371957 |
| 43 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.50354095 |
| 44 | Granulocytopenia (HP:0001913) | 2.48211011 |
| 45 | Congenital stationary night blindness (HP:0007642) | 2.44143871 |
| 46 | Increased IgM level (HP:0003496) | 2.41247549 |
| 47 | Progressive microcephaly (HP:0000253) | 2.39658830 |
| 48 | Bronchitis (HP:0012387) | 2.37007291 |
| 49 | Limb hypertonia (HP:0002509) | 2.35959557 |
| 50 | Vasculitis (HP:0002633) | 2.35417774 |
| 51 | Interstitial pulmonary disease (HP:0006530) | 2.32440594 |
| 52 | Radial bowing (HP:0002986) | 2.30966825 |
| 53 | Lipid accumulation in hepatocytes (HP:0006561) | 2.27784276 |
| 54 | Persistence of primary teeth (HP:0006335) | 2.27035729 |
| 55 | Hypoplasia of the ulna (HP:0003022) | 2.26925875 |
| 56 | Myositis (HP:0100614) | 2.26508295 |
| 57 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.26330753 |
| 58 | Decreased circulating renin level (HP:0003351) | 2.26276317 |
| 59 | Gastrointestinal inflammation (HP:0004386) | 2.26258071 |
| 60 | Prolonged neonatal jaundice (HP:0006579) | 2.23366432 |
| 61 | Basal ganglia calcification (HP:0002135) | 2.22496599 |
| 62 | Hypoproteinemia (HP:0003075) | 2.22120912 |
| 63 | Meningitis (HP:0001287) | 2.19706638 |
| 64 | Purpura (HP:0000979) | 2.15285629 |
| 65 | Poor head control (HP:0002421) | 2.14908785 |
| 66 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.12668299 |
| 67 | Retrobulbar optic neuritis (HP:0100654) | 2.11763646 |
| 68 | Optic neuritis (HP:0100653) | 2.11763646 |
| 69 | Autoimmune hemolytic anemia (HP:0001890) | 2.10272217 |
| 70 | Carpal bone hypoplasia (HP:0001498) | 2.07666655 |
| 71 | Exertional dyspnea (HP:0002875) | 2.07182870 |
| 72 | Micronodular cirrhosis (HP:0001413) | 2.07137395 |
| 73 | Viral hepatitis (HP:0006562) | 2.06679209 |
| 74 | Systemic lupus erythematosus (HP:0002725) | 2.05706550 |
| 75 | Lymphoma (HP:0002665) | 2.03787243 |
| 76 | Abnormality of the fovea (HP:0000493) | 2.03315924 |
| 77 | Villous atrophy (HP:0011473) | 2.02212496 |
| 78 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.02212496 |
| 79 | Fibular aplasia (HP:0002990) | 2.00294399 |
| 80 | Hemorrhage of the eye (HP:0011885) | 2.00155788 |
| 81 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.99280120 |
| 82 | Abnormality of the pleura (HP:0002103) | 1.98013987 |
| 83 | Forearm undergrowth (HP:0009821) | 1.96414951 |
| 84 | Microcytic anemia (HP:0001935) | 1.94898309 |
| 85 | Abnormal albumin level (HP:0012116) | 1.94431880 |
| 86 | Hypoalbuminemia (HP:0003073) | 1.94431880 |
| 87 | Constricted visual fields (HP:0001133) | 1.94431340 |
| 88 | Increased serum lactate (HP:0002151) | 1.90538528 |
| 89 | Dyschromatopsia (HP:0007641) | 1.90444966 |
| 90 | Orchitis (HP:0100796) | 1.89443168 |
| 91 | Aortic regurgitation (HP:0001659) | 1.88746372 |
| 92 | Abnormality of the pericardium (HP:0001697) | 1.88342417 |
| 93 | Stomach cancer (HP:0012126) | 1.86940638 |
| 94 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.85099095 |
| 95 | Lymphopenia (HP:0001888) | 1.82137621 |
| 96 | Hypergammaglobulinemia (HP:0010702) | 1.80000343 |
| 97 | Abnormality of the pons (HP:0007361) | 1.79516722 |
| 98 | Paralysis (HP:0003470) | 1.79239334 |
| 99 | Increased CSF lactate (HP:0002490) | 1.76677889 |
| 100 | Respiratory difficulties (HP:0002880) | 1.72871156 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.83529257 |
| 2 | EPHA3 | 5.55826191 |
| 3 | PBK | 5.17640295 |
| 4 | MAP4K1 | 3.71670919 |
| 5 | MUSK | 3.58884351 |
| 6 | EPHB1 | 3.54668947 |
| 7 | FGFR4 | 3.12042771 |
| 8 | NLK | 3.07712203 |
| 9 | IRAK4 | 2.71670192 |
| 10 | BRD4 | 2.05304219 |
| 11 | IRAK1 | 1.99656805 |
| 12 | ITK | 1.84968738 |
| 13 | FGFR3 | 1.83626246 |
| 14 | MAP2K3 | 1.75557337 |
| 15 | ADRBK2 | 1.70767128 |
| 16 | MAP3K3 | 1.64666844 |
| 17 | MST4 | 1.60385158 |
| 18 | FES | 1.60297252 |
| 19 | TLK1 | 1.48721063 |
| 20 | SRPK1 | 1.47602976 |
| 21 | CSK | 1.47352903 |
| 22 | ZAP70 | 1.44211673 |
| 23 | RPS6KA4 | 1.25700187 |
| 24 | HCK | 1.23791051 |
| 25 | PIK3CG | 1.20606009 |
| 26 | BTK | 1.18377568 |
| 27 | AKT3 | 1.14325889 |
| 28 | NME1 | 1.08836571 |
| 29 | TSSK6 | 1.06332488 |
| 30 | HIPK2 | 1.03413237 |
| 31 | SGK2 | 1.01650543 |
| 32 | SYK | 0.99649528 |
| 33 | STK4 | 0.97126830 |
| 34 | JAK1 | 0.96923008 |
| 35 | ZAK | 0.96788453 |
| 36 | LCK | 0.95938967 |
| 37 | SGK3 | 0.92451478 |
| 38 | VRK2 | 0.90938477 |
| 39 | PTK2B | 0.89830128 |
| 40 | TAOK3 | 0.89680666 |
| 41 | MAPK12 | 0.89214624 |
| 42 | RPS6KA5 | 0.88647016 |
| 43 | IKBKB | 0.86574804 |
| 44 | TNK2 | 0.80850448 |
| 45 | WNK4 | 0.80540527 |
| 46 | DYRK3 | 0.79766810 |
| 47 | MAP3K1 | 0.77005224 |
| 48 | JAK3 | 0.75370208 |
| 49 | TEC | 0.70772722 |
| 50 | EIF2AK1 | 0.66223241 |
| 51 | SGK223 | 0.65446526 |
| 52 | SGK494 | 0.65446526 |
| 53 | KDR | 0.63229500 |
| 54 | ALK | 0.62677557 |
| 55 | TYK2 | 0.62011534 |
| 56 | TNIK | 0.61286162 |
| 57 | MAP3K11 | 0.57604066 |
| 58 | GRK7 | 0.54284787 |
| 59 | DYRK2 | 0.51915147 |
| 60 | IKBKE | 0.50384827 |
| 61 | MAPKAPK2 | 0.50239036 |
| 62 | FER | 0.48713621 |
| 63 | DAPK2 | 0.46264200 |
| 64 | RET | 0.44998706 |
| 65 | LYN | 0.44992253 |
| 66 | TGFBR2 | 0.43684844 |
| 67 | STK38L | 0.42083807 |
| 68 | JAK2 | 0.40692732 |
| 69 | MAP3K12 | 0.36957460 |
| 70 | PRKCQ | 0.35680190 |
| 71 | CDK8 | 0.34913090 |
| 72 | BCKDK | 0.32093663 |
| 73 | TYRO3 | 0.31816640 |
| 74 | TAOK2 | 0.30797060 |
| 75 | VRK1 | 0.30412311 |
| 76 | CHUK | 0.29641986 |
| 77 | BLK | 0.29483624 |
| 78 | WNK1 | 0.28826833 |
| 79 | CAMK4 | 0.28636099 |
| 80 | MAP2K6 | 0.28530727 |
| 81 | NUAK1 | 0.28253591 |
| 82 | MAP3K8 | 0.28100527 |
| 83 | PIM1 | 0.27848614 |
| 84 | GRK6 | 0.27326886 |
| 85 | CSF1R | 0.24407492 |
| 86 | TESK2 | 0.23723429 |
| 87 | PRKD3 | 0.23614428 |
| 88 | ADRBK1 | 0.23269085 |
| 89 | PAK6 | 0.21079812 |
| 90 | MYLK | 0.20033621 |
| 91 | CDK4 | 0.18210573 |
| 92 | CLK1 | 0.17136931 |
| 93 | TBK1 | 0.16684466 |
| 94 | PASK | 0.15377495 |
| 95 | FGR | 0.14370425 |
| 96 | EIF2AK3 | 0.14330453 |
| 97 | DYRK1B | 0.11084168 |
| 98 | PRKCH | 0.09860323 |
| 99 | PDK1 | 0.09452381 |
| 100 | GRK1 | 0.09204493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 5.36782974 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 5.35242969 |
| 3 | Asthma_Homo sapiens_hsa05310 | 4.88661271 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.49103096 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 4.30936313 |
| 6 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.96459946 |
| 7 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.69617347 |
| 8 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.42105658 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.65221380 |
| 10 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 2.57194418 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.55578098 |
| 12 | Measles_Homo sapiens_hsa05162 | 2.03253110 |
| 13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.94978603 |
| 14 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.94927515 |
| 15 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.77405288 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.68114534 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.64512246 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 1.41236529 |
| 19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.24943137 |
| 20 | Proteasome_Homo sapiens_hsa03050 | 1.15735690 |
| 21 | Leishmaniasis_Homo sapiens_hsa05140 | 1.14133678 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.05412285 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.05101706 |
| 24 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.97499019 |
| 25 | Ribosome_Homo sapiens_hsa03010 | 0.92537455 |
| 26 | Protein export_Homo sapiens_hsa03060 | 0.87559445 |
| 27 | Malaria_Homo sapiens_hsa05144 | 0.80307939 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.78937124 |
| 29 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.78578565 |
| 30 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.78226772 |
| 31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.77578073 |
| 32 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.73912521 |
| 33 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.67774142 |
| 34 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.66749813 |
| 35 | RNA degradation_Homo sapiens_hsa03018 | 0.63979082 |
| 36 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.63711151 |
| 37 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.62866474 |
| 38 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.59638113 |
| 39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.57339821 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 0.56273086 |
| 41 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.55637964 |
| 42 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.55570231 |
| 43 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.55416215 |
| 44 | Parkinsons disease_Homo sapiens_hsa05012 | 0.55314094 |
| 45 | Platelet activation_Homo sapiens_hsa04611 | 0.54734256 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 0.49298998 |
| 47 | Phototransduction_Homo sapiens_hsa04744 | 0.46720536 |
| 48 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.46473500 |
| 49 | HTLV-I infection_Homo sapiens_hsa05166 | 0.46108492 |
| 50 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.45034656 |
| 51 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.42371131 |
| 52 | RNA transport_Homo sapiens_hsa03013 | 0.42065149 |
| 53 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.38052997 |
| 54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.37792456 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36695435 |
| 56 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.34973910 |
| 57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.33082496 |
| 58 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.32265180 |
| 59 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.31526408 |
| 60 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.31434939 |
| 61 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.31008223 |
| 62 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.30642833 |
| 63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.30339987 |
| 64 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.30246841 |
| 65 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29539631 |
| 66 | Renin secretion_Homo sapiens_hsa04924 | 0.28879351 |
| 67 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.28174543 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.28122265 |
| 69 | Hepatitis C_Homo sapiens_hsa05160 | 0.27389292 |
| 70 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.27362634 |
| 71 | Huntingtons disease_Homo sapiens_hsa05016 | 0.27103914 |
| 72 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.27075551 |
| 73 | Tuberculosis_Homo sapiens_hsa05152 | 0.26523887 |
| 74 | Shigellosis_Homo sapiens_hsa05131 | 0.25686981 |
| 75 | Apoptosis_Homo sapiens_hsa04210 | 0.24601238 |
| 76 | Insulin resistance_Homo sapiens_hsa04931 | 0.24393577 |
| 77 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.24366607 |
| 78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.24275963 |
| 79 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.22952740 |
| 80 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.21531332 |
| 81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.20290387 |
| 82 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.20039422 |
| 83 | Galactose metabolism_Homo sapiens_hsa00052 | 0.19846896 |
| 84 | Circadian rhythm_Homo sapiens_hsa04710 | 0.19014454 |
| 85 | Hepatitis B_Homo sapiens_hsa05161 | 0.18893502 |
| 86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.17975003 |
| 87 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.17329007 |
| 88 | Morphine addiction_Homo sapiens_hsa05032 | 0.16852525 |
| 89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.16807385 |
| 90 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.15811299 |
| 91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.15648143 |
| 92 | Pertussis_Homo sapiens_hsa05133 | 0.13976961 |
| 93 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.12510409 |
| 94 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.11745554 |
| 95 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.11114132 |
| 96 | Mismatch repair_Homo sapiens_hsa03430 | 0.10129263 |
| 97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.09397528 |
| 98 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.07090670 |
| 99 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.05936120 |
| 100 | Influenza A_Homo sapiens_hsa05164 | 0.05480648 |

