

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation by host of viral transcription (GO:0043922) | 7.80835503 |
| 2 | positive regulation of tolerance induction (GO:0002645) | 7.66530131 |
| 3 | regulation of T cell tolerance induction (GO:0002664) | 7.45188932 |
| 4 | regulation of lymphocyte chemotaxis (GO:1901623) | 7.25077463 |
| 5 | cytidine deamination (GO:0009972) | 7.07661546 |
| 6 | cytidine metabolic process (GO:0046087) | 7.07661546 |
| 7 | cytidine catabolic process (GO:0006216) | 7.07661546 |
| 8 | negative T cell selection (GO:0043383) | 6.88518181 |
| 9 | positive T cell selection (GO:0043368) | 6.54503796 |
| 10 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.38107059 |
| 11 | positive regulation of macrophage differentiation (GO:0045651) | 6.35650524 |
| 12 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.28193166 |
| 13 | regulation of tolerance induction (GO:0002643) | 6.16720204 |
| 14 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.15505990 |
| 15 | DNA deamination (GO:0045006) | 6.06400938 |
| 16 | positive regulation of lymphocyte migration (GO:2000403) | 5.82024003 |
| 17 | negative thymic T cell selection (GO:0045060) | 5.49639463 |
| 18 | cellular response to interleukin-15 (GO:0071350) | 5.42868962 |
| 19 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.34254403 |
| 20 | T cell selection (GO:0045058) | 5.26193176 |
| 21 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 5.07078427 |
| 22 | thymic T cell selection (GO:0045061) | 5.06393768 |
| 23 | regulation of alpha-beta T cell proliferation (GO:0046640) | 5.00401404 |
| 24 | response to interleukin-15 (GO:0070672) | 4.99934535 |
| 25 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.92740837 |
| 26 | modulation by host of viral transcription (GO:0043921) | 4.92003926 |
| 27 | modulation by host of symbiont transcription (GO:0052472) | 4.92003926 |
| 28 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.85580176 |
| 29 | positive thymic T cell selection (GO:0045059) | 4.84820601 |
| 30 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.75721390 |
| 31 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.72453406 |
| 32 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 4.69149349 |
| 33 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 4.62032498 |
| 34 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.60882604 |
| 35 | negative regulation of cell killing (GO:0031342) | 4.59999872 |
| 36 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.59999872 |
| 37 | tolerance induction (GO:0002507) | 4.57372803 |
| 38 | regulation of lymphocyte migration (GO:2000401) | 4.56292440 |
| 39 | mucosal-associated lymphoid tissue development (GO:0048537) | 4.54942512 |
| 40 | Peyers patch development (GO:0048541) | 4.54942512 |
| 41 | negative regulation of T cell mediated immunity (GO:0002710) | 4.47973005 |
| 42 | regulation of B cell differentiation (GO:0045577) | 4.41344444 |
| 43 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.36736892 |
| 44 | eosinophil chemotaxis (GO:0048245) | 4.20500412 |
| 45 | negative regulation of viral transcription (GO:0032897) | 4.14328265 |
| 46 | negative regulation of T cell differentiation in thymus (GO:0033085) | 4.11466148 |
| 47 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.08658515 |
| 48 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.08624197 |
| 49 | regulation of regulatory T cell differentiation (GO:0045589) | 4.02771343 |
| 50 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.99256588 |
| 51 | T cell migration (GO:0072678) | 3.93973648 |
| 52 | lymphocyte chemotaxis (GO:0048247) | 3.92363424 |
| 53 | regulation of T cell chemotaxis (GO:0010819) | 3.91908477 |
| 54 | positive regulation of T cell chemotaxis (GO:0010820) | 3.91908477 |
| 55 | proteasome assembly (GO:0043248) | 3.89343881 |
| 56 | T cell receptor signaling pathway (GO:0050852) | 3.86656594 |
| 57 | positive regulation of T cell apoptotic process (GO:0070234) | 3.85503220 |
| 58 | macrophage chemotaxis (GO:0048246) | 3.82807984 |
| 59 | eosinophil migration (GO:0072677) | 3.77093174 |
| 60 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.73463423 |
| 61 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.68178534 |
| 62 | regulation of gamma-delta T cell activation (GO:0046643) | 3.61754588 |
| 63 | positive regulation of astrocyte differentiation (GO:0048711) | 3.59622310 |
| 64 | regulation of macrophage differentiation (GO:0045649) | 3.59443369 |
| 65 | positive regulation of interleukin-2 production (GO:0032743) | 3.54850874 |
| 66 | negative regulation of T cell apoptotic process (GO:0070233) | 3.43855130 |
| 67 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.42226548 |
| 68 | negative regulation of B cell activation (GO:0050869) | 3.37348477 |
| 69 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 3.36623590 |
| 70 | NIK/NF-kappaB signaling (GO:0038061) | 3.35257789 |
| 71 | natural killer cell differentiation (GO:0001779) | 3.31397637 |
| 72 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.31280304 |
| 73 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.28470484 |
| 74 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.28204839 |
| 75 | regulation of calcium-mediated signaling (GO:0050848) | 3.27666261 |
| 76 | modification by host of symbiont morphology or physiology (GO:0051851) | 3.25394980 |
| 77 | cellular response to lithium ion (GO:0071285) | 3.22541675 |
| 78 | positive regulation of T cell migration (GO:2000406) | 3.22133716 |
| 79 | regulation of T cell cytokine production (GO:0002724) | 3.21780455 |
| 80 | regulation of T cell apoptotic process (GO:0070232) | 3.18354095 |
| 81 | necroptotic process (GO:0070266) | 3.17204486 |
| 82 | positive regulation of T cell mediated immunity (GO:0002711) | 3.13565438 |
| 83 | T cell costimulation (GO:0031295) | 3.11342116 |
| 84 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.10334713 |
| 85 | positive regulation of T cell cytokine production (GO:0002726) | 3.08960784 |
| 86 | dopamine biosynthetic process (GO:0042416) | 3.08141469 |
| 87 | response to insecticide (GO:0017085) | 3.08101563 |
| 88 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.08051369 |
| 89 | cellular defense response (GO:0006968) | 3.07662889 |
| 90 | lymphocyte costimulation (GO:0031294) | 3.07341378 |
| 91 | positive regulation of cell killing (GO:0031343) | 3.05812187 |
| 92 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.05632952 |
| 93 | signal peptide processing (GO:0006465) | 3.05121137 |
| 94 | regulation of interleukin-2 production (GO:0032663) | 3.04618870 |
| 95 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.03277144 |
| 96 | regulation of chronic inflammatory response (GO:0002676) | 3.02885983 |
| 97 | positive regulation of interleukin-4 production (GO:0032753) | 3.01962469 |
| 98 | interaction with symbiont (GO:0051702) | 3.00413035 |
| 99 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.99986237 |
| 100 | myeloid dendritic cell differentiation (GO:0043011) | 2.98845258 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.31355135 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.88610731 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.44786231 |
| 4 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.26623967 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.22367153 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.17000395 |
| 7 | MYB_26560356_Chip-Seq_TH2_Human | 3.01466113 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.86826898 |
| 9 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.86469627 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.71494528 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.65831694 |
| 12 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.41528081 |
| 13 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.37462125 |
| 14 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.35128654 |
| 15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.19964633 |
| 16 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 12.9837722 |
| 17 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.98872014 |
| 18 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.97251111 |
| 19 | MAF_26560356_Chip-Seq_TH1_Human | 1.95207868 |
| 20 | MYB_26560356_Chip-Seq_TH1_Human | 1.88685744 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.86294427 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.86155854 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.85605849 |
| 24 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.78317303 |
| 25 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.73939432 |
| 26 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.65913516 |
| 27 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.65284993 |
| 28 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63698655 |
| 29 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.59450922 |
| 30 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.58151289 |
| 31 | UTX_26944678_Chip-Seq_JUKART_Human | 1.55858233 |
| 32 | MAF_26560356_Chip-Seq_TH2_Human | 1.55318254 |
| 33 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45442233 |
| 34 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.43473936 |
| 35 | GATA3_26560356_Chip-Seq_TH2_Human | 1.42450471 |
| 36 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.38520463 |
| 37 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.37142833 |
| 38 | MYC_22102868_ChIP-Seq_BL_Human | 1.36617173 |
| 39 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.35791372 |
| 40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.29186875 |
| 41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.25240378 |
| 42 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.23518990 |
| 43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.19528159 |
| 44 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.19201294 |
| 45 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.14220652 |
| 46 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.12566755 |
| 47 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11282952 |
| 48 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.09289907 |
| 49 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.08914770 |
| 50 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.07877862 |
| 51 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.06731679 |
| 52 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.06443665 |
| 53 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.05865966 |
| 54 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.05750047 |
| 55 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.04106813 |
| 56 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.03994733 |
| 57 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.02881140 |
| 58 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.02798351 |
| 59 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.00661417 |
| 60 | GATA3_26560356_Chip-Seq_TH1_Human | 0.95695246 |
| 61 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.95098641 |
| 62 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90450495 |
| 63 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89832947 |
| 64 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.89040375 |
| 65 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.88720665 |
| 66 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88568806 |
| 67 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.87629052 |
| 68 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.87491098 |
| 69 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.86793777 |
| 70 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.82702908 |
| 71 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.79036756 |
| 72 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.78878961 |
| 73 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.78646853 |
| 74 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.76288670 |
| 75 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.75016737 |
| 76 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.74065118 |
| 77 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.73735200 |
| 78 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.70069926 |
| 79 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.69270998 |
| 80 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.68876397 |
| 81 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.67146656 |
| 82 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.67111897 |
| 83 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.66902640 |
| 84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.64836641 |
| 85 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.64771975 |
| 86 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.64355189 |
| 87 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.63865514 |
| 88 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.63864041 |
| 89 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.63806970 |
| 90 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.62303344 |
| 91 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.61076640 |
| 92 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.61029832 |
| 93 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.60689079 |
| 94 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.60430891 |
| 95 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.59075993 |
| 96 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.58742828 |
| 97 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.57916758 |
| 98 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.56900852 |
| 99 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.56591474 |
| 100 | SPI1_23127762_ChIP-Seq_K562_Human | 0.56498785 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 5.72809862 |
| 2 | MP0009333_abnormal_splenocyte_physiolog | 4.47045217 |
| 3 | MP0006082_CNS_inflammation | 4.34004273 |
| 4 | MP0005671_abnormal_response_to | 4.15261726 |
| 5 | MP0001873_stomach_inflammation | 4.05592913 |
| 6 | MP0001790_abnormal_immune_system | 3.94610241 |
| 7 | MP0005387_immune_system_phenotype | 3.94610241 |
| 8 | MP0005000_abnormal_immune_tolerance | 3.14944731 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.87852095 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 2.84930282 |
| 11 | MP0001800_abnormal_humoral_immune | 2.84713766 |
| 12 | MP0002277_abnormal_respiratory_mucosa | 2.78016733 |
| 13 | MP0003436_decreased_susceptibility_to | 2.69450563 |
| 14 | MP0002723_abnormal_immune_serum | 2.65420569 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.57807879 |
| 16 | MP0002405_respiratory_system_inflammati | 2.54702449 |
| 17 | MP0001819_abnormal_immune_cell | 2.53920704 |
| 18 | MP0000703_abnormal_thymus_morphology | 2.46427524 |
| 19 | MP0002398_abnormal_bone_marrow | 2.35097852 |
| 20 | MP0000716_abnormal_immune_system | 2.20786021 |
| 21 | MP0003866_abnormal_defecation | 2.20763151 |
| 22 | MP0010155_abnormal_intestine_physiology | 2.13179182 |
| 23 | MP0002452_abnormal_antigen_presenting | 2.07075156 |
| 24 | MP0000685_abnormal_immune_system | 2.05281824 |
| 25 | MP0009785_altered_susceptibility_to | 2.03173203 |
| 26 | MP0008007_abnormal_cellular_replicative | 2.01582345 |
| 27 | MP0005025_abnormal_response_to | 2.01408419 |
| 28 | MP0000569_abnormal_digit_pigmentation | 1.83499320 |
| 29 | MP0001984_abnormal_olfaction | 1.80458409 |
| 30 | MP0002722_abnormal_immune_system | 1.79727848 |
| 31 | MP0003300_gastrointestinal_ulcer | 1.76984885 |
| 32 | MP0000689_abnormal_spleen_morphology | 1.70564439 |
| 33 | MP0004381_abnormal_hair_follicle | 1.66100285 |
| 34 | MP0002429_abnormal_blood_cell | 1.63503513 |
| 35 | MP0005075_abnormal_melanosome_morpholog | 1.61969585 |
| 36 | MP0004947_skin_inflammation | 1.61225842 |
| 37 | MP0000465_gastrointestinal_hemorrhage | 1.60745221 |
| 38 | MP0002419_abnormal_innate_immunity | 1.59845009 |
| 39 | MP0001188_hyperpigmentation | 1.58612393 |
| 40 | MP0001502_abnormal_circadian_rhythm | 1.53968419 |
| 41 | MP0001845_abnormal_inflammatory_respons | 1.52722822 |
| 42 | MP0005310_abnormal_salivary_gland | 1.46721699 |
| 43 | MP0005464_abnormal_platelet_physiology | 1.45587160 |
| 44 | MP0003786_premature_aging | 1.38270452 |
| 45 | MP0001348_abnormal_lacrimal_gland | 1.34145322 |
| 46 | MP0008569_lethality_at_weaning | 1.32384973 |
| 47 | MP0002933_joint_inflammation | 1.26486163 |
| 48 | MP0001853_heart_inflammation | 1.21133072 |
| 49 | MP0002132_abnormal_respiratory_system | 1.15412766 |
| 50 | MP0002163_abnormal_gland_morphology | 1.12676190 |
| 51 | MP0002998_abnormal_bone_remodeling | 1.10531484 |
| 52 | MP0002138_abnormal_hepatobiliary_system | 1.07563901 |
| 53 | MP0001919_abnormal_reproductive_system | 1.04538732 |
| 54 | MP0003724_increased_susceptibility_to | 1.03107650 |
| 55 | MP0004043_abnormal_pH_regulation | 1.01808361 |
| 56 | MP0005408_hypopigmentation | 0.99147368 |
| 57 | MP0003448_altered_tumor_morphology | 0.98718057 |
| 58 | MP0002166_altered_tumor_susceptibility | 0.97385577 |
| 59 | MP0008469_abnormal_protein_level | 0.95189798 |
| 60 | MP0004742_abnormal_vestibular_system | 0.92925250 |
| 61 | MP0000920_abnormal_myelination | 0.85612303 |
| 62 | MP0000371_diluted_coat_color | 0.85593704 |
| 63 | MP0000604_amyloidosis | 0.85585281 |
| 64 | MP0005076_abnormal_cell_differentiation | 0.85038611 |
| 65 | MP0001881_abnormal_mammary_gland | 0.83851090 |
| 66 | MP0008873_increased_physiological_sensi | 0.82370889 |
| 67 | MP0009763_increased_sensitivity_to | 0.81353270 |
| 68 | MP0000490_abnormal_crypts_of | 0.80667040 |
| 69 | MP0003195_calcinosis | 0.80618531 |
| 70 | MP0001533_abnormal_skeleton_physiology | 0.78677080 |
| 71 | MP0002019_abnormal_tumor_incidence | 0.74765262 |
| 72 | MP0004142_abnormal_muscle_tone | 0.74396948 |
| 73 | MP0001851_eye_inflammation | 0.71986650 |
| 74 | MP0001905_abnormal_dopamine_level | 0.67906885 |
| 75 | MP0001765_abnormal_ion_homeostasis | 0.63959043 |
| 76 | MP0001663_abnormal_digestive_system | 0.60471945 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.58539673 |
| 78 | MP0003795_abnormal_bone_structure | 0.56900392 |
| 79 | MP0000609_abnormal_liver_physiology | 0.56659997 |
| 80 | MP0003186_abnormal_redox_activity | 0.56141194 |
| 81 | MP0005379_endocrine/exocrine_gland_phen | 0.56065568 |
| 82 | MP0000627_abnormal_mammary_gland | 0.53361548 |
| 83 | MP0000858_altered_metastatic_potential | 0.50492102 |
| 84 | MP0003183_abnormal_peptide_metabolism | 0.50337367 |
| 85 | MP0003567_abnormal_fetal_cardiomyocyte | 0.50143046 |
| 86 | MP0002006_tumorigenesis | 0.49717561 |
| 87 | MP0002970_abnormal_white_adipose | 0.49157383 |
| 88 | MP0005334_abnormal_fat_pad | 0.48625583 |
| 89 | MP0003045_fibrosis | 0.47361407 |
| 90 | MP0001191_abnormal_skin_condition | 0.47111657 |
| 91 | MP0003303_peritoneal_inflammation | 0.46846789 |
| 92 | MP0005389_reproductive_system_phenotype | 0.45964137 |
| 93 | MP0003959_abnormal_lean_body | 0.44000344 |
| 94 | MP0002396_abnormal_hematopoietic_system | 0.42874483 |
| 95 | MP0005410_abnormal_fertilization | 0.41925701 |
| 96 | MP0002928_abnormal_bile_duct | 0.41183779 |
| 97 | MP0010307_abnormal_tumor_latency | 0.40553529 |
| 98 | MP0009384_cardiac_valve_regurgitation | 0.40030624 |
| 99 | MP0000477_abnormal_intestine_morphology | 0.39323897 |
| 100 | MP0001186_pigmentation_phenotype | 0.39126299 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune hemolytic anemia (HP:0001890) | 7.45674485 |
| 2 | Abnormality of T cell number (HP:0011839) | 5.85222997 |
| 3 | T lymphocytopenia (HP:0005403) | 5.46746795 |
| 4 | Gastrointestinal infarctions (HP:0005244) | 5.33759023 |
| 5 | Abnormality of eosinophils (HP:0001879) | 5.08147466 |
| 6 | Eosinophilia (HP:0001880) | 5.05933315 |
| 7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.54990757 |
| 8 | Stomatitis (HP:0010280) | 4.47148383 |
| 9 | Granulocytopenia (HP:0001913) | 4.45210479 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.28712366 |
| 11 | Alveolar cell carcinoma (HP:0006519) | 4.21246225 |
| 12 | Abnormality of T cells (HP:0002843) | 4.18512557 |
| 13 | Hemiplegia (HP:0002301) | 4.18116374 |
| 14 | IgM deficiency (HP:0002850) | 4.13043984 |
| 15 | Vasculitis (HP:0002633) | 4.10857227 |
| 16 | Increased IgM level (HP:0003496) | 4.07238162 |
| 17 | Leukocytosis (HP:0001974) | 3.97805390 |
| 18 | Neoplasm of the tracheobronchial system (HP:0100552) | 3.81598958 |
| 19 | Chest pain (HP:0100749) | 3.74651500 |
| 20 | Severe combined immunodeficiency (HP:0004430) | 3.73422100 |
| 21 | Chronic diarrhea (HP:0002028) | 3.70749344 |
| 22 | Ureteral obstruction (HP:0006000) | 3.62155422 |
| 23 | Pulmonary infiltrates (HP:0002113) | 3.58909120 |
| 24 | Ureteral stenosis (HP:0000071) | 3.57184678 |
| 25 | Conjugated hyperbilirubinemia (HP:0002908) | 3.51647751 |
| 26 | Obstructive lung disease (HP:0006536) | 3.51457274 |
| 27 | Chronic obstructive pulmonary disease (HP:0006510) | 3.51457274 |
| 28 | Abnormality of the prostate (HP:0008775) | 3.44425944 |
| 29 | IgG deficiency (HP:0004315) | 3.40536451 |
| 30 | Meningitis (HP:0001287) | 3.38593505 |
| 31 | Gangrene (HP:0100758) | 3.38325752 |
| 32 | Hemoptysis (HP:0002105) | 3.35752983 |
| 33 | Mediastinal lymphadenopathy (HP:0100721) | 3.35430421 |
| 34 | Encephalitis (HP:0002383) | 3.25115535 |
| 35 | Recurrent bronchitis (HP:0002837) | 3.23774832 |
| 36 | Myositis (HP:0100614) | 3.22891611 |
| 37 | Recurrent fungal infections (HP:0002841) | 3.19227621 |
| 38 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.15743452 |
| 39 | Autoimmune thrombocytopenia (HP:0001973) | 3.08862817 |
| 40 | Diplopia (HP:0000651) | 3.06817486 |
| 41 | Abnormality of binocular vision (HP:0011514) | 3.06817486 |
| 42 | Orchitis (HP:0100796) | 3.02456804 |
| 43 | Lymphopenia (HP:0001888) | 2.99496612 |
| 44 | Abnormality of T cell physiology (HP:0011840) | 2.98351476 |
| 45 | Optic neuritis (HP:0100653) | 2.91831746 |
| 46 | Retrobulbar optic neuritis (HP:0100654) | 2.91831746 |
| 47 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.91499139 |
| 48 | Recurrent cutaneous fungal infections (HP:0011370) | 2.91499139 |
| 49 | Combined immunodeficiency (HP:0005387) | 2.89774767 |
| 50 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.87500473 |
| 51 | Hypoproteinemia (HP:0003075) | 2.77685859 |
| 52 | Abnormality of alanine metabolism (HP:0010916) | 2.75511620 |
| 53 | Hyperalaninemia (HP:0003348) | 2.75511620 |
| 54 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.75511620 |
| 55 | Joint swelling (HP:0001386) | 2.70965979 |
| 56 | Hypoplasia of the thymus (HP:0000778) | 2.70197462 |
| 57 | Hypochromic anemia (HP:0001931) | 2.70139212 |
| 58 | Thyroiditis (HP:0100646) | 2.68902791 |
| 59 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.68240478 |
| 60 | Pulmonary embolism (HP:0002204) | 2.66136003 |
| 61 | Amaurosis fugax (HP:0100576) | 2.65517054 |
| 62 | Abnormality of macrophages (HP:0004311) | 2.61161149 |
| 63 | Recurrent bacterial skin infections (HP:0005406) | 2.58330168 |
| 64 | Increased cerebral lipofuscin (HP:0011813) | 2.56867378 |
| 65 | Pustule (HP:0200039) | 2.53031767 |
| 66 | Anorexia (HP:0002039) | 2.49194204 |
| 67 | Abnormality of the pleura (HP:0002103) | 2.45790276 |
| 68 | Rhabdomyosarcoma (HP:0002859) | 2.38742183 |
| 69 | Recurrent skin infections (HP:0001581) | 2.38119361 |
| 70 | Renal cortical cysts (HP:0000803) | 2.37373168 |
| 71 | Lymphoma (HP:0002665) | 2.34951238 |
| 72 | Recurrent abscess formation (HP:0002722) | 2.30489604 |
| 73 | Premature loss of primary teeth (HP:0006323) | 2.23165439 |
| 74 | Agammaglobulinemia (HP:0004432) | 2.22825745 |
| 75 | Abnormality of the right ventricle (HP:0001707) | 2.22328135 |
| 76 | Glomerulopathy (HP:0100820) | 2.21323273 |
| 77 | Eczematoid dermatitis (HP:0000976) | 2.21262767 |
| 78 | Abnormality of the pericardium (HP:0001697) | 2.20642441 |
| 79 | Renal tubular acidosis (HP:0001947) | 2.16327618 |
| 80 | Bronchitis (HP:0012387) | 2.14008761 |
| 81 | Hypergammaglobulinemia (HP:0010702) | 2.13081113 |
| 82 | Spontaneous hematomas (HP:0007420) | 2.12875311 |
| 83 | Periodontitis (HP:0000704) | 2.09518265 |
| 84 | Abnormality of the radial head (HP:0003995) | 2.08674580 |
| 85 | Scanning speech (HP:0002168) | 2.04870547 |
| 86 | Increased CSF protein (HP:0002922) | 1.99439297 |
| 87 | Dislocated radial head (HP:0003083) | 1.98384851 |
| 88 | Keratoconjunctivitis sicca (HP:0001097) | 1.95572820 |
| 89 | Recurrent viral infections (HP:0004429) | 1.93362201 |
| 90 | Abnormality of the alveolar ridges (HP:0006477) | 1.91309120 |
| 91 | Malignant hyperthermia (HP:0002047) | 1.89779532 |
| 92 | Arterial thrombosis (HP:0004420) | 1.89356655 |
| 93 | Polyneuropathy (HP:0001271) | 1.86957024 |
| 94 | Skin rash (HP:0000988) | 1.83276832 |
| 95 | Abnormality of male internal genitalia (HP:0000022) | 1.81296678 |
| 96 | Congenital stationary night blindness (HP:0007642) | 1.80223570 |
| 97 | Keratoconjunctivitis (HP:0001096) | 1.80148796 |
| 98 | Epistaxis (HP:0000421) | 1.79797305 |
| 99 | Pulmonary fibrosis (HP:0002206) | 1.78671695 |
| 100 | Restrictive lung disease (HP:0002091) | 1.74374720 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 7.29833122 |
| 2 | MAP4K1 | 5.53194233 |
| 3 | ITK | 4.28819092 |
| 4 | BUB1 | 4.23968408 |
| 5 | KDR | 3.96417400 |
| 6 | AKT3 | 3.39140765 |
| 7 | CSK | 2.76633988 |
| 8 | TNK2 | 2.73758533 |
| 9 | PRKCQ | 2.16948674 |
| 10 | SRPK1 | 1.93429349 |
| 11 | MAP3K11 | 1.86234171 |
| 12 | IKBKE | 1.84698816 |
| 13 | LCK | 1.83199995 |
| 14 | FGFR1 | 1.82480813 |
| 15 | TBK1 | 1.78456465 |
| 16 | JAK3 | 1.77054192 |
| 17 | MAP2K7 | 1.66423336 |
| 18 | BTK | 1.65702501 |
| 19 | IKBKB | 1.53523543 |
| 20 | TESK2 | 1.51924129 |
| 21 | MARK3 | 1.51095972 |
| 22 | FES | 1.50434084 |
| 23 | ZAP70 | 1.48190625 |
| 24 | MAP2K6 | 1.46299866 |
| 25 | IRAK4 | 1.46185806 |
| 26 | SYK | 1.32958115 |
| 27 | PRKCH | 1.25509476 |
| 28 | TEC | 1.25263049 |
| 29 | PAK2 | 1.17814982 |
| 30 | HCK | 1.10375707 |
| 31 | LYN | 1.07789873 |
| 32 | BCR | 1.01453654 |
| 33 | GRK6 | 1.00932898 |
| 34 | WNK4 | 0.94128964 |
| 35 | MAP3K13 | 0.93831291 |
| 36 | CAMKK2 | 0.89929984 |
| 37 | TYK2 | 0.89234125 |
| 38 | MAP3K1 | 0.89176747 |
| 39 | MAP3K14 | 0.86983682 |
| 40 | PASK | 0.84826003 |
| 41 | CSF1R | 0.82455459 |
| 42 | BRAF | 0.81161278 |
| 43 | ERBB3 | 0.76624965 |
| 44 | RIPK4 | 0.76504411 |
| 45 | MAPK12 | 0.72147764 |
| 46 | ERN1 | 0.71680788 |
| 47 | JAK1 | 0.69050886 |
| 48 | STK24 | 0.66682121 |
| 49 | RPS6KB1 | 0.66263781 |
| 50 | FYN | 0.64701581 |
| 51 | PRKD2 | 0.64002478 |
| 52 | IRAK1 | 0.62662712 |
| 53 | TAOK3 | 0.61932165 |
| 54 | PRKCZ | 0.57156261 |
| 55 | IRAK2 | 0.56348554 |
| 56 | CHUK | 0.56018307 |
| 57 | CAMKK1 | 0.54493682 |
| 58 | AURKA | 0.49476817 |
| 59 | JAK2 | 0.48164143 |
| 60 | BLK | 0.47626007 |
| 61 | INSR | 0.44698017 |
| 62 | NLK | 0.42952982 |
| 63 | WNK1 | 0.41278500 |
| 64 | MAP3K3 | 0.38988411 |
| 65 | IGF1R | 0.37194755 |
| 66 | RPS6KA1 | 0.36664503 |
| 67 | TAOK2 | 0.36504600 |
| 68 | PDK1 | 0.35989892 |
| 69 | MAP3K7 | 0.35727019 |
| 70 | KIT | 0.34376041 |
| 71 | SGK2 | 0.33010274 |
| 72 | PDGFRB | 0.31298470 |
| 73 | MAPK3 | 0.31211459 |
| 74 | SGK3 | 0.30726862 |
| 75 | TYRO3 | 0.30459312 |
| 76 | FGFR4 | 0.29738689 |
| 77 | MAP2K3 | 0.28747702 |
| 78 | PRKACG | 0.27269052 |
| 79 | CDK4 | 0.27208623 |
| 80 | MAPK7 | 0.27192857 |
| 81 | PLK2 | 0.26217664 |
| 82 | PRPF4B | 0.25264577 |
| 83 | PIM1 | 0.25252748 |
| 84 | MAPKAPK2 | 0.24836152 |
| 85 | MAPK9 | 0.24256755 |
| 86 | PRKCA | 0.24078442 |
| 87 | SIK3 | 0.23797378 |
| 88 | EPHB1 | 0.23015971 |
| 89 | CDK3 | 0.22682063 |
| 90 | CSNK1A1 | 0.22597732 |
| 91 | TAOK1 | 0.20932231 |
| 92 | PIK3CA | 0.19861903 |
| 93 | GRK7 | 0.17012059 |
| 94 | VRK1 | 0.15230233 |
| 95 | NUAK1 | 0.14819424 |
| 96 | CLK1 | 0.14536618 |
| 97 | PAK3 | 0.13890700 |
| 98 | SGK1 | 0.13701019 |
| 99 | PRKACA | 0.13329800 |
| 100 | PRKCD | 0.12852526 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.53505070 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 4.02185753 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.86838351 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.51490972 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.38185364 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.10057721 |
| 7 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 3.00592533 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.99283767 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.93414030 |
| 10 | Measles_Homo sapiens_hsa05162 | 2.83726399 |
| 11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.71982843 |
| 12 | Salmonella infection_Homo sapiens_hsa05132 | 2.54282188 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.50463506 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.29894709 |
| 15 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 2.24677944 |
| 16 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.21458097 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.14631655 |
| 18 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 2.13033184 |
| 19 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.92618443 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.90992492 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.76212234 |
| 22 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.68469449 |
| 23 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.64316552 |
| 24 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.45266816 |
| 25 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.44920168 |
| 26 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.33624656 |
| 27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.29789712 |
| 28 | Proteasome_Homo sapiens_hsa03050 | 1.22870078 |
| 29 | Leishmaniasis_Homo sapiens_hsa05140 | 1.21870742 |
| 30 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.14349481 |
| 31 | Protein export_Homo sapiens_hsa03060 | 1.09326022 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.09007989 |
| 33 | Apoptosis_Homo sapiens_hsa04210 | 1.02762619 |
| 34 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.98062141 |
| 35 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.92728484 |
| 36 | Malaria_Homo sapiens_hsa05144 | 0.90416895 |
| 37 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.89481084 |
| 38 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.86114700 |
| 39 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.85015301 |
| 40 | Shigellosis_Homo sapiens_hsa05131 | 0.84290942 |
| 41 | Hepatitis B_Homo sapiens_hsa05161 | 0.83541252 |
| 42 | Viral myocarditis_Homo sapiens_hsa05416 | 0.81047066 |
| 43 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.78712238 |
| 44 | HTLV-I infection_Homo sapiens_hsa05166 | 0.76970629 |
| 45 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.74229656 |
| 46 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.69384397 |
| 47 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.66263105 |
| 48 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.65477201 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.64968666 |
| 50 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.64071489 |
| 51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.63147966 |
| 52 | Tuberculosis_Homo sapiens_hsa05152 | 0.62440752 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.61242035 |
| 54 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.60917688 |
| 55 | Platelet activation_Homo sapiens_hsa04611 | 0.57626519 |
| 56 | Influenza A_Homo sapiens_hsa05164 | 0.56799640 |
| 57 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.54007871 |
| 58 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.50664864 |
| 59 | Hepatitis C_Homo sapiens_hsa05160 | 0.48049868 |
| 60 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.46741196 |
| 61 | Asthma_Homo sapiens_hsa05310 | 0.46030923 |
| 62 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45135253 |
| 63 | Pertussis_Homo sapiens_hsa05133 | 0.44224197 |
| 64 | Legionellosis_Homo sapiens_hsa05134 | 0.43179542 |
| 65 | Endocytosis_Homo sapiens_hsa04144 | 0.42611437 |
| 66 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.42597306 |
| 67 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41203804 |
| 68 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.40577938 |
| 69 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.38814237 |
| 70 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.38637874 |
| 71 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.37381307 |
| 72 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.35995910 |
| 73 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.35962298 |
| 74 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.35583452 |
| 75 | Colorectal cancer_Homo sapiens_hsa05210 | 0.32363585 |
| 76 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.31986487 |
| 77 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.28149780 |
| 78 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.25471326 |
| 79 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.24673824 |
| 80 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.23514743 |
| 81 | Renin secretion_Homo sapiens_hsa04924 | 0.20485244 |
| 82 | Long-term potentiation_Homo sapiens_hsa04720 | 0.20285451 |
| 83 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.19526224 |
| 84 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.19222855 |
| 85 | Circadian rhythm_Homo sapiens_hsa04710 | 0.18769341 |
| 86 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.18252847 |
| 87 | Thyroid cancer_Homo sapiens_hsa05216 | 0.15236452 |
| 88 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.14577568 |
| 89 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.13482261 |
| 90 | Lysosome_Homo sapiens_hsa04142 | 0.11644343 |
| 91 | Prion diseases_Homo sapiens_hsa05020 | 0.10086047 |
| 92 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.09431240 |
| 93 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.09172150 |
| 94 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.09049059 |
| 95 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.07589894 |
| 96 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.07333247 |
| 97 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.07229022 |
| 98 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.06825110 |
| 99 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.06514428 |
| 100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.05862206 |

