TRAV30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)6.26546648
2tolerance induction (GO:0002507)6.22142829
3negative thymic T cell selection (GO:0045060)6.09215897
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.05110879
5positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.89468984
6positive regulation of gamma-delta T cell activation (GO:0046645)5.86991202
7positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.78942033
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.70141918
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.69395311
10negative regulation of cell killing (GO:0031342)5.58871050
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.58871050
12regulation of T cell tolerance induction (GO:0002664)5.54863146
13antigen processing and presentation of endogenous antigen (GO:0019883)5.31790990
14positive regulation of tolerance induction (GO:0002645)5.16516685
15CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)4.98152760
16regulation of regulatory T cell differentiation (GO:0045589)4.93954313
17response to interleukin-15 (GO:0070672)4.83527896
18regulation of interleukin-2 biosynthetic process (GO:0045076)4.82096496
19regulation of gamma-delta T cell differentiation (GO:0045586)4.75404078
20thymic T cell selection (GO:0045061)4.71103820
21regulation of tolerance induction (GO:0002643)4.63414973
22cellular response to interleukin-15 (GO:0071350)4.59786921
23positive regulation of granulocyte differentiation (GO:0030854)4.59558594
24regulation of isotype switching to IgG isotypes (GO:0048302)4.53823241
25T cell selection (GO:0045058)4.44147391
26regulation of gamma-delta T cell activation (GO:0046643)4.40820237
27negative regulation of T cell mediated immunity (GO:0002710)4.40634570
28regulation of B cell receptor signaling pathway (GO:0050855)4.25168596
29positive T cell selection (GO:0043368)4.14020227
30regulation of alpha-beta T cell proliferation (GO:0046640)4.02832581
31T cell migration (GO:0072678)4.00839568
32positive regulation of B cell differentiation (GO:0045579)4.00703094
33leukocyte aggregation (GO:0070486)3.95988724
34production of molecular mediator involved in inflammatory response (GO:0002532)3.92415289
35activated T cell proliferation (GO:0050798)3.88729582
36negative regulation of lymphocyte mediated immunity (GO:0002707)3.79584288
37positive thymic T cell selection (GO:0045059)3.78557825
38regulation of transforming growth factor beta1 production (GO:0032908)3.77503038
39T cell homeostasis (GO:0043029)3.73752530
40alpha-beta T cell differentiation (GO:0046632)3.59231718
41regulation of B cell differentiation (GO:0045577)3.50865675
42regulation of T-helper 2 cell differentiation (GO:0045628)3.48961977
43positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.46418762
44T cell receptor signaling pathway (GO:0050852)3.45710814
45positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.44998782
46defense response to protozoan (GO:0042832)3.43819944
47NIK/NF-kappaB signaling (GO:0038061)3.41483273
48regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.35999888
49regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)3.34835791
50modulation by symbiont of host defense response (GO:0052031)3.31966338
51modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.31966338
52modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.31966338
53positive regulation by organism of defense response of other organism involved in symbiotic interact3.31966338
54modulation by symbiont of host immune response (GO:0052553)3.31966338
55positive regulation by symbiont of host defense response (GO:0052509)3.31966338
56alpha-beta T cell activation (GO:0046631)3.31159158
57interferon-gamma production (GO:0032609)3.29551841
58T cell lineage commitment (GO:0002360)3.28098566
59positive regulation of interleukin-2 production (GO:0032743)3.27974016
60antigen receptor-mediated signaling pathway (GO:0050851)3.27012888
61positive regulation of interleukin-4 production (GO:0032753)3.26721164
62mast cell activation (GO:0045576)3.25523324
63negative regulation of leukocyte mediated immunity (GO:0002704)3.25260258
64positive regulation of alpha-beta T cell proliferation (GO:0046641)3.24495600
65regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.22192632
66regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.19432852
67regulation of natural killer cell mediated immunity (GO:0002715)3.19432852
68response to protozoan (GO:0001562)3.16859952
69natural killer cell differentiation (GO:0001779)3.15364768
70regulation of alpha-beta T cell activation (GO:0046634)3.13016039
71regulation of T cell mediated cytotoxicity (GO:0001914)3.12656978
72T cell differentiation (GO:0030217)3.12047955
73positive regulation of T cell differentiation in thymus (GO:0033089)3.11312743
74response to peptidoglycan (GO:0032494)3.08599834
75cellular response to type I interferon (GO:0071357)3.05538534
76type I interferon signaling pathway (GO:0060337)3.05538534
77regulation of granulocyte differentiation (GO:0030852)3.04745026
78response to type I interferon (GO:0034340)3.03558576
79CD4-positive, alpha-beta T cell differentiation (GO:0043367)3.02978334
80neutrophil mediated immunity (GO:0002446)3.01119900
81positive regulation of alpha-beta T cell activation (GO:0046635)2.96738061
82cell wall macromolecule metabolic process (GO:0044036)2.95084148
83positive regulation of T cell mediated cytotoxicity (GO:0001916)2.95038875
84positive regulation of humoral immune response (GO:0002922)2.94939179
85regulation of T cell receptor signaling pathway (GO:0050856)2.94099010
86CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.93839589
87T-helper cell differentiation (GO:0042093)2.93839589
88negative regulation of meiotic cell cycle (GO:0051447)2.91429462
89positive regulation of type 2 immune response (GO:0002830)2.89793177
90CD4-positive, alpha-beta T cell activation (GO:0035710)2.88416081
91myeloid leukocyte mediated immunity (GO:0002444)2.87221557
92regulation of leukocyte mediated cytotoxicity (GO:0001910)2.86002728
93B cell receptor signaling pathway (GO:0050853)2.85998856
94interleukin-6-mediated signaling pathway (GO:0070102)2.83053734
95positive regulation of macrophage differentiation (GO:0045651)2.82997385
96G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.80053614
97positive regulation of alpha-beta T cell differentiation (GO:0046638)2.79917757
98positive regulation of immunoglobulin production (GO:0002639)2.79377287
99lymphocyte homeostasis (GO:0002260)2.79270360
100Peyers patch development (GO:0048541)2.78956915

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.17917225
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.07112229
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.69637116
4BP1_19119308_ChIP-ChIP_Hs578T_Human3.95771831
5RUNX_20019798_ChIP-Seq_JUKART_Human3.63973036
6STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.53655851
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.45155323
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.43897651
9MYB_26560356_Chip-Seq_TH2_Human3.38365162
10ELF1_17652178_ChIP-ChIP_JURKAT_Human3.37495479
11IRF8_21731497_ChIP-ChIP_J774_Mouse3.09340350
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.99846806
13MAF_26560356_Chip-Seq_TH1_Human2.86424215
14FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.81814769
15STAT4_19710469_ChIP-ChIP_TH1__Mouse2.81774403
16SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.74553824
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.69205919
18MYB_26560356_Chip-Seq_TH1_Human2.66377207
19UTX_26944678_Chip-Seq_JUKART_Human2.40143149
20SMAD_19615063_ChIP-ChIP_OVARY_Human2.33817103
21SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.31747867
22SCL_19346495_ChIP-Seq_HPC-7_Human2.21846697
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.18148896
24SPI1_23547873_ChIP-Seq_NB4_Human2.13541995
25GATA3_27048872_Chip-Seq_THYMUS_Human2.10167883
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.07216063
27MAF_26560356_Chip-Seq_TH2_Human2.05751000
28NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.03983158
29MYB_21317192_ChIP-Seq_ERMYB_Mouse2.03740510
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.91326568
31RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.91047908
32MYC_22102868_ChIP-Seq_BL_Human1.84288587
33IRF8_27001747_Chip-Seq_BMDM_Mouse1.82215501
34RUNX1_22412390_ChIP-Seq_EML_Mouse1.76795211
35VDR_21846776_ChIP-Seq_THP-1_Human1.76470835
36NOTCH1_21737748_ChIP-Seq_TLL_Human1.76012927
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.75371408
38STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.74921974
39E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.74181830
40GATA3_26560356_Chip-Seq_TH2_Human1.62871424
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.61093274
42VDR_24763502_ChIP-Seq_THP-1_Human1.57855345
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.56982327
44MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.51968939
45LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.50881787
46TCF7_22412390_ChIP-Seq_EML_Mouse1.50160342
47KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.46447682
48RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.43629491
49BRD4_27068464_Chip-Seq_AML-cells_Mouse1.40968984
50EGR1_19374776_ChIP-ChIP_THP-1_Human1.38186191
51VDR_23849224_ChIP-Seq_CD4+_Human1.38092189
52SPI1_23127762_ChIP-Seq_K562_Human1.36080841
53CIITA_25753668_ChIP-Seq_RAJI_Human1.33849880
54TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.32223885
55FOXP3_21729870_ChIP-Seq_TREG_Human1.25149302
56CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.23132548
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22446988
58KDM2B_26808549_Chip-Seq_DND41_Human1.18042318
59KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.17045844
60LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.16384672
61TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.14726521
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14385700
63TFEB_21752829_ChIP-Seq_HELA_Human1.11860731
64STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.09509191
65GATA1_19941826_ChIP-Seq_K562_Human1.09177553
66CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08857754
67GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08334950
68CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07644860
69GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07211475
70Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.06894215
71PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02252268
72GATA1_22383799_ChIP-Seq_G1ME_Mouse1.02049128
73PU_27001747_Chip-Seq_BMDM_Mouse1.01241658
74HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98853335
75PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98490071
76CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96123471
77NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.96110946
78GATA1_19941827_ChIP-Seq_MEL_Mouse0.95457921
79TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95060150
80FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92791805
81VDR_24787735_ChIP-Seq_THP-1_Human0.91671560
82PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90692831
83KDM2B_26808549_Chip-Seq_SUP-B15_Human0.90073989
84PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87741095
85CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86499060
86KDM2B_26808549_Chip-Seq_JURKAT_Human0.83576895
87ELK3_25401928_ChIP-Seq_HUVEC_Human0.83500894
88CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.80884626
89PU.1_20513432_ChIP-Seq_Bcells_Mouse0.80430079
90ESR1_20079471_ChIP-ChIP_T-47D_Human0.80360717
91TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.79849422
92NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.79516784
93SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78808727
94BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.77478056
95GABP_17652178_ChIP-ChIP_JURKAT_Human0.76985175
96RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75789332
97EST1_17652178_ChIP-ChIP_JURKAT_Human0.75735030
98HIF1A_21447827_ChIP-Seq_MCF-7_Human0.75370376
99HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.74822317
100NCOR1_26117541_ChIP-Seq_K562_Human0.74776475

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.44821442
2MP0005671_abnormal_response_to3.41882655
3MP0009333_abnormal_splenocyte_physiolog3.37346229
4MP0006082_CNS_inflammation3.33811260
5MP0003436_decreased_susceptibility_to3.04874530
6MP0001873_stomach_inflammation2.97207063
7MP0001800_abnormal_humoral_immune2.89747034
8MP0005000_abnormal_immune_tolerance2.89345775
9MP0001835_abnormal_antigen_presentation2.76791520
10MP0001790_abnormal_immune_system2.75989772
11MP0005387_immune_system_phenotype2.75989772
12MP0003724_increased_susceptibility_to2.61082742
13MP0009785_altered_susceptibility_to2.54843262
14MP0002723_abnormal_immune_serum2.42893713
15MP0002420_abnormal_adaptive_immunity2.38738472
16MP0002148_abnormal_hypersensitivity_rea2.35916181
17MP0001819_abnormal_immune_cell2.34368376
18MP0000703_abnormal_thymus_morphology2.30043826
19MP0002009_preneoplasia2.26110046
20MP0000465_gastrointestinal_hemorrhage2.25851821
21MP0005025_abnormal_response_to2.25148984
22MP0002405_respiratory_system_inflammati2.24831518
23MP0002452_abnormal_antigen_presenting2.23426316
24MP0002398_abnormal_bone_marrow2.21907035
25MP0000685_abnormal_immune_system2.21575622
26MP0004947_skin_inflammation2.10462158
27MP0002419_abnormal_innate_immunity2.06959225
28MP0000716_abnormal_immune_system2.01986487
29MP0002166_altered_tumor_susceptibility2.00753953
30MP0003866_abnormal_defecation1.97822383
31MP0003300_gastrointestinal_ulcer1.96831120
32MP0002006_tumorigenesis1.89643532
33MP0002396_abnormal_hematopoietic_system1.89483527
34MP0005075_abnormal_melanosome_morpholog1.86627554
35MP0002722_abnormal_immune_system1.84753236
36MP0000689_abnormal_spleen_morphology1.82559959
37MP0005464_abnormal_platelet_physiology1.81100233
38MP0002138_abnormal_hepatobiliary_system1.80118642
39MP0010155_abnormal_intestine_physiology1.77813167
40MP0003303_peritoneal_inflammation1.76658400
41MP0002933_joint_inflammation1.70933661
42MP0002132_abnormal_respiratory_system1.65198331
43MP0001851_eye_inflammation1.63388372
44MP0004381_abnormal_hair_follicle1.61249853
45MP0002429_abnormal_blood_cell1.58480936
46MP0001845_abnormal_inflammatory_respons1.57236100
47MP0005310_abnormal_salivary_gland1.45283695
48MP0001545_abnormal_hematopoietic_system1.36626115
49MP0005397_hematopoietic_system_phenotyp1.36626115
50MP0001853_heart_inflammation1.36612588
51MP0005451_abnormal_body_composition1.33720733
52MP0008260_abnormal_autophagy1.27847883
53MP0002796_impaired_skin_barrier1.25588612
54MP0004808_abnormal_hematopoietic_stem1.22432502
55MP0008469_abnormal_protein_level1.22156381
56MP0008057_abnormal_DNA_replication1.18326873
57MP0000858_altered_metastatic_potential1.17594626
58MP0002277_abnormal_respiratory_mucosa1.17358302
59MP0001764_abnormal_homeostasis1.14490280
60MP0001533_abnormal_skeleton_physiology1.13479952
61MP0005166_decreased_susceptibility_to1.12462735
62MP0003656_abnormal_erythrocyte_physiolo1.00745708
63MP0002998_abnormal_bone_remodeling0.98027801
64MP0004264_abnormal_extraembryonic_tissu0.97578095
65MP0009763_increased_sensitivity_to0.87251675
66MP0002019_abnormal_tumor_incidence0.83803620
67MP0000490_abnormal_crypts_of0.83242662
68MP0009278_abnormal_bone_marrow0.81604101
69MP0003172_abnormal_lysosome_physiology0.80702299
70MP0001663_abnormal_digestive_system0.80109203
71MP0001348_abnormal_lacrimal_gland0.79703181
72MP0005164_abnormal_response_to0.73209153
73MP0000604_amyloidosis0.71881061
74MP0008004_abnormal_stomach_pH0.71790891
75MP0008874_decreased_physiological_sensi0.70236371
76MP0002163_abnormal_gland_morphology0.69738327
77MP0005501_abnormal_skin_physiology0.68662822
78MP0005360_urolithiasis0.67707295
79MP0004510_myositis0.66543233
80MP0009764_decreased_sensitivity_to0.66159048
81MP0003191_abnormal_cellular_cholesterol0.65240362
82MP0002693_abnormal_pancreas_physiology0.65007317
83MP0003183_abnormal_peptide_metabolism0.64431373
84MP0003448_altered_tumor_morphology0.63935636
85MP0002136_abnormal_kidney_physiology0.63557684
86MP0008873_increased_physiological_sensi0.63472339
87MP0000249_abnormal_blood_vessel0.61827265
88MP0005408_hypopigmentation0.60935134
89MP0003806_abnormal_nucleotide_metabolis0.60518076
90MP0008872_abnormal_physiological_respon0.60075724
91MP0002332_abnormal_exercise_endurance0.59712980
92MP0000609_abnormal_liver_physiology0.57252452
93MP0000598_abnormal_liver_morphology0.57130623
94MP0001765_abnormal_ion_homeostasis0.53431438
95MP0005645_abnormal_hypothalamus_physiol0.52557429
96MP0004883_abnormal_blood_vessel0.52395281
97MP0009643_abnormal_urine_homeostasis0.51990958
98MP0001501_abnormal_sleep_pattern0.49985011
99MP0005376_homeostasis/metabolism_phenot0.46693386
100MP0000367_abnormal_coat/_hair0.46674935

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)6.83228246
2Elevated erythrocyte sedimentation rate (HP:0003565)5.23834996
3T lymphocytopenia (HP:0005403)5.10558690
4Abnormality of T cell number (HP:0011839)5.00899465
5Autoimmune hemolytic anemia (HP:0001890)5.00726489
6Myositis (HP:0100614)4.57201648
7Recurrent bacterial skin infections (HP:0005406)4.51880031
8Eczematoid dermatitis (HP:0000976)4.48314507
9Mediastinal lymphadenopathy (HP:0100721)4.30960137
10Abnormality of T cells (HP:0002843)4.10446735
11Abnormal delayed hypersensitivity skin test (HP:0002963)3.96096456
12Orchitis (HP:0100796)3.83437197
13Joint swelling (HP:0001386)3.83123371
14Recurrent abscess formation (HP:0002722)3.80337169
15Severe combined immunodeficiency (HP:0004430)3.69509492
16Retrobulbar optic neuritis (HP:0100654)3.68119445
17Optic neuritis (HP:0100653)3.68119445
18Increased IgM level (HP:0003496)3.59158117
19Panhypogammaglobulinemia (HP:0003139)3.57475772
20Recurrent fungal infections (HP:0002841)3.57029839
21Keratoconjunctivitis sicca (HP:0001097)3.33714906
22IgG deficiency (HP:0004315)3.29742550
23Encephalitis (HP:0002383)3.23828076
24Abnormality of macrophages (HP:0004311)3.23680504
25Prolonged bleeding time (HP:0003010)3.23334294
26Meningitis (HP:0001287)3.22554249
27Recurrent viral infections (HP:0004429)3.20103758
28Abnormality of T cell physiology (HP:0011840)3.19613680
29Pustule (HP:0200039)3.16884291
30Recurrent skin infections (HP:0001581)3.16527340
31Abnormality of eosinophils (HP:0001879)3.08009679
32Keratoconjunctivitis (HP:0001096)3.07125391
33Granulocytopenia (HP:0001913)3.06591903
34Vasculitis (HP:0002633)2.99241274
35Recurrent cutaneous fungal infections (HP:0011370)2.96148674
36Chronic mucocutaneous candidiasis (HP:0002728)2.96148674
37Pulmonary infiltrates (HP:0002113)2.94162618
38Eosinophilia (HP:0001880)2.94028494
39Leukocytosis (HP:0001974)2.93780297
40Recurrent bronchitis (HP:0002837)2.92313632
41IgM deficiency (HP:0002850)2.89351417
42Obstructive lung disease (HP:0006536)2.87025336
43Chronic obstructive pulmonary disease (HP:0006510)2.87025336
44Combined immunodeficiency (HP:0005387)2.81380311
45Gastrointestinal infarctions (HP:0005244)2.67999096
46Abnormality of the prostate (HP:0008775)2.65655261
47Lymphopenia (HP:0001888)2.63139888
48Inflammation of the large intestine (HP:0002037)2.60416182
49Spontaneous hematomas (HP:0007420)2.59665487
50Gastrointestinal inflammation (HP:0004386)2.58297825
51Abnormality of the pleura (HP:0002103)2.57572005
52Abnormality of cells of the lymphoid lineage (HP:0012140)2.55885378
53Epistaxis (HP:0000421)2.55779984
54Abnormality of the heme biosynthetic pathway (HP:0010472)2.49078039
55Chest pain (HP:0100749)2.48985820
56Recurrent gram-negative bacterial infections (HP:0005420)2.48314013
57Urticaria (HP:0001025)2.47495768
58Agammaglobulinemia (HP:0004432)2.47470571
59Chronic diarrhea (HP:0002028)2.47291032
60Increased serum ferritin (HP:0003281)2.45594906
61Thyroiditis (HP:0100646)2.41894045
62Gingival bleeding (HP:0000225)2.41594245
63Hemoptysis (HP:0002105)2.39890339
64Abnormality of dental color (HP:0011073)2.39629153
65Skin rash (HP:0000988)2.38445051
66Hypochromic anemia (HP:0001931)2.38311373
67Increased IgE level (HP:0003212)2.36929135
68Pulmonary embolism (HP:0002204)2.26201146
69Petechiae (HP:0000967)2.24343486
70Abnormality of iron homeostasis (HP:0011031)2.21943250
71Oral leukoplakia (HP:0002745)2.21723708
72Hypergammaglobulinemia (HP:0010702)2.21264840
73Lymphoma (HP:0002665)2.20633586
74Fatigue (HP:0012378)2.19997890
75Papilledema (HP:0001085)2.19591192
76Abnormality of the pericardium (HP:0001697)2.18073583
77Abnormality of B cell number (HP:0010975)2.14614211
78Anorexia (HP:0002039)2.12081523
79Alveolar cell carcinoma (HP:0006519)2.11144348
80Chronic otitis media (HP:0000389)2.09198673
81Papilloma (HP:0012740)2.07483352
82Verrucae (HP:0200043)2.07483352
83Gingivitis (HP:0000230)2.07135643
84Neoplasm of the tracheobronchial system (HP:0100552)2.05118718
85Glucose intolerance (HP:0000833)2.05009756
86Gangrene (HP:0100758)2.03761277
87Hematochezia (HP:0002573)2.03417704
88Microcytic anemia (HP:0001935)2.02271868
89Hepatitis (HP:0012115)2.02196209
90Abnormality of transition element cation homeostasis (HP:0011030)2.01928540
91B lymphocytopenia (HP:0010976)2.01462576
92Polycythemia (HP:0001901)1.98790720
93Abnormality of the frontal sinuses (HP:0002687)1.98141840
94Abnormality of male internal genitalia (HP:0000022)1.97304182
95Abnormality of the fingertips (HP:0001211)1.95781947
96Autoimmune thrombocytopenia (HP:0001973)1.94665730
97Hypochromic microcytic anemia (HP:0004840)1.93076566
98Polyneuropathy (HP:0001271)1.92811155
99Hypoplasia of the thymus (HP:0000778)1.91827494
100Skin ulcer (HP:0200042)1.89564730

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.22205518
2MST44.89614199
3MAP4K14.48344118
4ITK2.74857427
5SIK32.40235532
6TYK22.33184849
7ZAP702.28197995
8TAOK32.25477773
9BTK2.19964056
10GRK62.14244486
11TEC2.09546413
12CAMKK22.08240575
13FES2.04387292
14IKBKE2.02332460
15PRPF4B1.91119099
16CSK1.85601303
17NLK1.83244345
18RIPK41.81709683
19JAK31.80390379
20PASK1.76774160
21LCK1.72103330
22ERN11.67664583
23STK101.61270894
24MAP3K131.52724422
25SYK1.46168328
26HCK1.45084383
27FGFR41.34346635
28PRKCQ1.33926209
29MAP3K141.31653758
30JAK11.28364350
31MARK31.28338562
32TNK21.27371791
33PIM21.26435937
34PIM11.25938868
35CAMKK11.25797751
36TESK11.24055804
37LRRK21.23825197
38IKBKB1.22259194
39MAP3K31.15264117
40LYN1.14457811
41RAF11.09529862
42NEK61.04023331
43IRAK41.02648281
44EPHB11.02203827
45SIK21.01594657
46TAOK21.00178316
47FGFR30.97777891
48KDR0.96224723
49SMG10.93722374
50TBK10.93712708
51BLK0.92725666
52JAK20.90228034
53HIPK20.86670604
54MAP2K30.86574784
55SIK10.86084221
56MAP3K110.82651480
57TAOK10.81075522
58KIT0.78379432
59SCYL20.78147348
60CSF1R0.71248917
61YES10.65917597
62MAP3K100.64866159
63MAPK110.64053500
64MAP3K70.61319167
65MAPK70.59667800
66CDK40.58611144
67VRK20.57723988
68MARK20.57188646
69CDK60.55442044
70MAPK120.54462163
71MAP3K10.54120909
72TGFBR20.47649831
73PDK10.47232187
74CLK10.45858062
75FYN0.45153822
76PTK60.44490686
77MAPK30.41342937
78CDK90.41238736
79PIK3CA0.39439011
80MAPKAPK20.37681899
81NME10.35208255
82NUAK10.33249748
83PDGFRB0.32739285
84EIF2AK30.32637711
85ARAF0.32000536
86CHUK0.31838594
87STK380.30836715
88CDK190.29425216
89ADRBK10.27981662
90EPHA30.27788064
91PRKCI0.27588144
92TYRO30.26449969
93PRKCD0.26449421
94MAP3K120.25839695
95PIK3CG0.25054273
96EGFR0.24582308
97ABL10.23652666
98TAF10.21424698
99DYRK1B0.20674790
100MAP3K80.19961341

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.53662221
2Graft-versus-host disease_Homo sapiens_hsa053323.29661813
3T cell receptor signaling pathway_Homo sapiens_hsa046603.18734631
4Measles_Homo sapiens_hsa051622.93040042
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.78987572
6Autoimmune thyroid disease_Homo sapiens_hsa053202.67273484
7Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.56860856
8Allograft rejection_Homo sapiens_hsa053302.48679607
9Hematopoietic cell lineage_Homo sapiens_hsa046402.44278329
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.37728937
11Osteoclast differentiation_Homo sapiens_hsa043802.23329182
12Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.08814649
13TNF signaling pathway_Homo sapiens_hsa046682.01361345
14Acute myeloid leukemia_Homo sapiens_hsa052211.96336526
15NOD-like receptor signaling pathway_Homo sapiens_hsa046211.94481978
16Type I diabetes mellitus_Homo sapiens_hsa049401.85886266
17Rheumatoid arthritis_Homo sapiens_hsa053231.84382585
18Jak-STAT signaling pathway_Homo sapiens_hsa046301.78573113
19Herpes simplex infection_Homo sapiens_hsa051681.68156010
20Legionellosis_Homo sapiens_hsa051341.65523075
21African trypanosomiasis_Homo sapiens_hsa051431.65343193
22Leishmaniasis_Homo sapiens_hsa051401.63501550
23Chemokine signaling pathway_Homo sapiens_hsa040621.62385822
24Toll-like receptor signaling pathway_Homo sapiens_hsa046201.62365066
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.60736944
26B cell receptor signaling pathway_Homo sapiens_hsa046621.59414861
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.57255772
28Antigen processing and presentation_Homo sapiens_hsa046121.53752517
29Hepatitis B_Homo sapiens_hsa051611.52668207
30Malaria_Homo sapiens_hsa051441.51535708
31Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.50394079
32Viral myocarditis_Homo sapiens_hsa054161.38563231
33Influenza A_Homo sapiens_hsa051641.34880306
34Pertussis_Homo sapiens_hsa051331.34687357
35Non-small cell lung cancer_Homo sapiens_hsa052231.15489075
36Tuberculosis_Homo sapiens_hsa051521.15349868
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.13361714
38Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.13245123
39Staphylococcus aureus infection_Homo sapiens_hsa051501.11479415
40Thyroid cancer_Homo sapiens_hsa052161.08155762
41Pancreatic cancer_Homo sapiens_hsa052121.02062229
42Apoptosis_Homo sapiens_hsa042101.00761184
43FoxO signaling pathway_Homo sapiens_hsa040680.98652483
44HTLV-I infection_Homo sapiens_hsa051660.96261355
45Chronic myeloid leukemia_Homo sapiens_hsa052200.95765202
46Leukocyte transendothelial migration_Homo sapiens_hsa046700.93908074
47Salmonella infection_Homo sapiens_hsa051320.93778553
48Renal cell carcinoma_Homo sapiens_hsa052110.92829808
49AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.91053451
50Viral carcinogenesis_Homo sapiens_hsa052030.90283556
51Epstein-Barr virus infection_Homo sapiens_hsa051690.87433680
52Ribosome_Homo sapiens_hsa030100.87271944
53Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.84501385
54SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84431995
55Hepatitis C_Homo sapiens_hsa051600.84265199
56Toxoplasmosis_Homo sapiens_hsa051450.81918767
57Prion diseases_Homo sapiens_hsa050200.81430961
58Colorectal cancer_Homo sapiens_hsa052100.81035462
59Platelet activation_Homo sapiens_hsa046110.76308000
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74695999
61Shigellosis_Homo sapiens_hsa051310.61020219
62HIF-1 signaling pathway_Homo sapiens_hsa040660.60271766
63Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60213454
64Endometrial cancer_Homo sapiens_hsa052130.59891930
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56452641
66Amoebiasis_Homo sapiens_hsa051460.55755968
67Regulation of autophagy_Homo sapiens_hsa041400.55685324
68ErbB signaling pathway_Homo sapiens_hsa040120.55346881
69Sulfur metabolism_Homo sapiens_hsa009200.54869894
70Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.52907354
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52387718
72MAPK signaling pathway_Homo sapiens_hsa040100.50167665
73Endocytosis_Homo sapiens_hsa041440.49381829
74Prolactin signaling pathway_Homo sapiens_hsa049170.48478868
75Insulin resistance_Homo sapiens_hsa049310.48398494
76Circadian rhythm_Homo sapiens_hsa047100.47205493
77Sulfur relay system_Homo sapiens_hsa041220.45373582
78VEGF signaling pathway_Homo sapiens_hsa043700.43163494
79Other glycan degradation_Homo sapiens_hsa005110.42873563
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.41965087
81Asthma_Homo sapiens_hsa053100.39652037
82Drug metabolism - other enzymes_Homo sapiens_hsa009830.37330118
83Prostate cancer_Homo sapiens_hsa052150.36363814
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.35869912
85Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.33390578
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32036466
87Vitamin B6 metabolism_Homo sapiens_hsa007500.31128831
88Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.30543355
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.26280688
90Inositol phosphate metabolism_Homo sapiens_hsa005620.25988019
91p53 signaling pathway_Homo sapiens_hsa041150.25845363
92Dorso-ventral axis formation_Homo sapiens_hsa043200.23432610
93Longevity regulating pathway - mammal_Homo sapiens_hsa042110.21261869
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.20512128
95Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19965608
96Notch signaling pathway_Homo sapiens_hsa043300.19737351
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.19007715
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.19000644
99Ras signaling pathway_Homo sapiens_hsa040140.19000465
100mTOR signaling pathway_Homo sapiens_hsa041500.18296927

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »