

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 6.26546648 |
| 2 | tolerance induction (GO:0002507) | 6.22142829 |
| 3 | negative thymic T cell selection (GO:0045060) | 6.09215897 |
| 4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.05110879 |
| 5 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.89468984 |
| 6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.86991202 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.78942033 |
| 8 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.70141918 |
| 9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.69395311 |
| 10 | negative regulation of cell killing (GO:0031342) | 5.58871050 |
| 11 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.58871050 |
| 12 | regulation of T cell tolerance induction (GO:0002664) | 5.54863146 |
| 13 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.31790990 |
| 14 | positive regulation of tolerance induction (GO:0002645) | 5.16516685 |
| 15 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.98152760 |
| 16 | regulation of regulatory T cell differentiation (GO:0045589) | 4.93954313 |
| 17 | response to interleukin-15 (GO:0070672) | 4.83527896 |
| 18 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.82096496 |
| 19 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.75404078 |
| 20 | thymic T cell selection (GO:0045061) | 4.71103820 |
| 21 | regulation of tolerance induction (GO:0002643) | 4.63414973 |
| 22 | cellular response to interleukin-15 (GO:0071350) | 4.59786921 |
| 23 | positive regulation of granulocyte differentiation (GO:0030854) | 4.59558594 |
| 24 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.53823241 |
| 25 | T cell selection (GO:0045058) | 4.44147391 |
| 26 | regulation of gamma-delta T cell activation (GO:0046643) | 4.40820237 |
| 27 | negative regulation of T cell mediated immunity (GO:0002710) | 4.40634570 |
| 28 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.25168596 |
| 29 | positive T cell selection (GO:0043368) | 4.14020227 |
| 30 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.02832581 |
| 31 | T cell migration (GO:0072678) | 4.00839568 |
| 32 | positive regulation of B cell differentiation (GO:0045579) | 4.00703094 |
| 33 | leukocyte aggregation (GO:0070486) | 3.95988724 |
| 34 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.92415289 |
| 35 | activated T cell proliferation (GO:0050798) | 3.88729582 |
| 36 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.79584288 |
| 37 | positive thymic T cell selection (GO:0045059) | 3.78557825 |
| 38 | regulation of transforming growth factor beta1 production (GO:0032908) | 3.77503038 |
| 39 | T cell homeostasis (GO:0043029) | 3.73752530 |
| 40 | alpha-beta T cell differentiation (GO:0046632) | 3.59231718 |
| 41 | regulation of B cell differentiation (GO:0045577) | 3.50865675 |
| 42 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.48961977 |
| 43 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.46418762 |
| 44 | T cell receptor signaling pathway (GO:0050852) | 3.45710814 |
| 45 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.44998782 |
| 46 | defense response to protozoan (GO:0042832) | 3.43819944 |
| 47 | NIK/NF-kappaB signaling (GO:0038061) | 3.41483273 |
| 48 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.35999888 |
| 49 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.34835791 |
| 50 | modulation by symbiont of host defense response (GO:0052031) | 3.31966338 |
| 51 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.31966338 |
| 52 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.31966338 |
| 53 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.31966338 |
| 54 | modulation by symbiont of host immune response (GO:0052553) | 3.31966338 |
| 55 | positive regulation by symbiont of host defense response (GO:0052509) | 3.31966338 |
| 56 | alpha-beta T cell activation (GO:0046631) | 3.31159158 |
| 57 | interferon-gamma production (GO:0032609) | 3.29551841 |
| 58 | T cell lineage commitment (GO:0002360) | 3.28098566 |
| 59 | positive regulation of interleukin-2 production (GO:0032743) | 3.27974016 |
| 60 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.27012888 |
| 61 | positive regulation of interleukin-4 production (GO:0032753) | 3.26721164 |
| 62 | mast cell activation (GO:0045576) | 3.25523324 |
| 63 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.25260258 |
| 64 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.24495600 |
| 65 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.22192632 |
| 66 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.19432852 |
| 67 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.19432852 |
| 68 | response to protozoan (GO:0001562) | 3.16859952 |
| 69 | natural killer cell differentiation (GO:0001779) | 3.15364768 |
| 70 | regulation of alpha-beta T cell activation (GO:0046634) | 3.13016039 |
| 71 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.12656978 |
| 72 | T cell differentiation (GO:0030217) | 3.12047955 |
| 73 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.11312743 |
| 74 | response to peptidoglycan (GO:0032494) | 3.08599834 |
| 75 | cellular response to type I interferon (GO:0071357) | 3.05538534 |
| 76 | type I interferon signaling pathway (GO:0060337) | 3.05538534 |
| 77 | regulation of granulocyte differentiation (GO:0030852) | 3.04745026 |
| 78 | response to type I interferon (GO:0034340) | 3.03558576 |
| 79 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.02978334 |
| 80 | neutrophil mediated immunity (GO:0002446) | 3.01119900 |
| 81 | positive regulation of alpha-beta T cell activation (GO:0046635) | 2.96738061 |
| 82 | cell wall macromolecule metabolic process (GO:0044036) | 2.95084148 |
| 83 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.95038875 |
| 84 | positive regulation of humoral immune response (GO:0002922) | 2.94939179 |
| 85 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.94099010 |
| 86 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.93839589 |
| 87 | T-helper cell differentiation (GO:0042093) | 2.93839589 |
| 88 | negative regulation of meiotic cell cycle (GO:0051447) | 2.91429462 |
| 89 | positive regulation of type 2 immune response (GO:0002830) | 2.89793177 |
| 90 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 2.88416081 |
| 91 | myeloid leukocyte mediated immunity (GO:0002444) | 2.87221557 |
| 92 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.86002728 |
| 93 | B cell receptor signaling pathway (GO:0050853) | 2.85998856 |
| 94 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.83053734 |
| 95 | positive regulation of macrophage differentiation (GO:0045651) | 2.82997385 |
| 96 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.80053614 |
| 97 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 2.79917757 |
| 98 | positive regulation of immunoglobulin production (GO:0002639) | 2.79377287 |
| 99 | lymphocyte homeostasis (GO:0002260) | 2.79270360 |
| 100 | Peyers patch development (GO:0048541) | 2.78956915 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.17917225 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.07112229 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.69637116 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.95771831 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.63973036 |
| 6 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.53655851 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.45155323 |
| 8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.43897651 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.38365162 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.37495479 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.09340350 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.99846806 |
| 13 | MAF_26560356_Chip-Seq_TH1_Human | 2.86424215 |
| 14 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.81814769 |
| 15 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.81774403 |
| 16 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.74553824 |
| 17 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.69205919 |
| 18 | MYB_26560356_Chip-Seq_TH1_Human | 2.66377207 |
| 19 | UTX_26944678_Chip-Seq_JUKART_Human | 2.40143149 |
| 20 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.33817103 |
| 21 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.31747867 |
| 22 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.21846697 |
| 23 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.18148896 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.13541995 |
| 25 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.10167883 |
| 26 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.07216063 |
| 27 | MAF_26560356_Chip-Seq_TH2_Human | 2.05751000 |
| 28 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.03983158 |
| 29 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.03740510 |
| 30 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.91326568 |
| 31 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.91047908 |
| 32 | MYC_22102868_ChIP-Seq_BL_Human | 1.84288587 |
| 33 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.82215501 |
| 34 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.76795211 |
| 35 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.76470835 |
| 36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.76012927 |
| 37 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.75371408 |
| 38 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.74921974 |
| 39 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.74181830 |
| 40 | GATA3_26560356_Chip-Seq_TH2_Human | 1.62871424 |
| 41 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61093274 |
| 42 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.57855345 |
| 43 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.56982327 |
| 44 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51968939 |
| 45 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50881787 |
| 46 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.50160342 |
| 47 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.46447682 |
| 48 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.43629491 |
| 49 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.40968984 |
| 50 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.38186191 |
| 51 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.38092189 |
| 52 | SPI1_23127762_ChIP-Seq_K562_Human | 1.36080841 |
| 53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.33849880 |
| 54 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.32223885 |
| 55 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.25149302 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.23132548 |
| 57 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22446988 |
| 58 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.18042318 |
| 59 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.17045844 |
| 60 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.16384672 |
| 61 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14726521 |
| 62 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.14385700 |
| 63 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.11860731 |
| 64 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.09509191 |
| 65 | GATA1_19941826_ChIP-Seq_K562_Human | 1.09177553 |
| 66 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08857754 |
| 67 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.08334950 |
| 68 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07644860 |
| 69 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.07211475 |
| 70 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.06894215 |
| 71 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.02252268 |
| 72 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.02049128 |
| 73 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.01241658 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98853335 |
| 75 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.98490071 |
| 76 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96123471 |
| 77 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.96110946 |
| 78 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.95457921 |
| 79 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95060150 |
| 80 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92791805 |
| 81 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.91671560 |
| 82 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90692831 |
| 83 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.90073989 |
| 84 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.87741095 |
| 85 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.86499060 |
| 86 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.83576895 |
| 87 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.83500894 |
| 88 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.80884626 |
| 89 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.80430079 |
| 90 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.80360717 |
| 91 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.79849422 |
| 92 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.79516784 |
| 93 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.78808727 |
| 94 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.77478056 |
| 95 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.76985175 |
| 96 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75789332 |
| 97 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.75735030 |
| 98 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.75370376 |
| 99 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.74822317 |
| 100 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.74776475 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.44821442 |
| 2 | MP0005671_abnormal_response_to | 3.41882655 |
| 3 | MP0009333_abnormal_splenocyte_physiolog | 3.37346229 |
| 4 | MP0006082_CNS_inflammation | 3.33811260 |
| 5 | MP0003436_decreased_susceptibility_to | 3.04874530 |
| 6 | MP0001873_stomach_inflammation | 2.97207063 |
| 7 | MP0001800_abnormal_humoral_immune | 2.89747034 |
| 8 | MP0005000_abnormal_immune_tolerance | 2.89345775 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.76791520 |
| 10 | MP0001790_abnormal_immune_system | 2.75989772 |
| 11 | MP0005387_immune_system_phenotype | 2.75989772 |
| 12 | MP0003724_increased_susceptibility_to | 2.61082742 |
| 13 | MP0009785_altered_susceptibility_to | 2.54843262 |
| 14 | MP0002723_abnormal_immune_serum | 2.42893713 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.38738472 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 2.35916181 |
| 17 | MP0001819_abnormal_immune_cell | 2.34368376 |
| 18 | MP0000703_abnormal_thymus_morphology | 2.30043826 |
| 19 | MP0002009_preneoplasia | 2.26110046 |
| 20 | MP0000465_gastrointestinal_hemorrhage | 2.25851821 |
| 21 | MP0005025_abnormal_response_to | 2.25148984 |
| 22 | MP0002405_respiratory_system_inflammati | 2.24831518 |
| 23 | MP0002452_abnormal_antigen_presenting | 2.23426316 |
| 24 | MP0002398_abnormal_bone_marrow | 2.21907035 |
| 25 | MP0000685_abnormal_immune_system | 2.21575622 |
| 26 | MP0004947_skin_inflammation | 2.10462158 |
| 27 | MP0002419_abnormal_innate_immunity | 2.06959225 |
| 28 | MP0000716_abnormal_immune_system | 2.01986487 |
| 29 | MP0002166_altered_tumor_susceptibility | 2.00753953 |
| 30 | MP0003866_abnormal_defecation | 1.97822383 |
| 31 | MP0003300_gastrointestinal_ulcer | 1.96831120 |
| 32 | MP0002006_tumorigenesis | 1.89643532 |
| 33 | MP0002396_abnormal_hematopoietic_system | 1.89483527 |
| 34 | MP0005075_abnormal_melanosome_morpholog | 1.86627554 |
| 35 | MP0002722_abnormal_immune_system | 1.84753236 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.82559959 |
| 37 | MP0005464_abnormal_platelet_physiology | 1.81100233 |
| 38 | MP0002138_abnormal_hepatobiliary_system | 1.80118642 |
| 39 | MP0010155_abnormal_intestine_physiology | 1.77813167 |
| 40 | MP0003303_peritoneal_inflammation | 1.76658400 |
| 41 | MP0002933_joint_inflammation | 1.70933661 |
| 42 | MP0002132_abnormal_respiratory_system | 1.65198331 |
| 43 | MP0001851_eye_inflammation | 1.63388372 |
| 44 | MP0004381_abnormal_hair_follicle | 1.61249853 |
| 45 | MP0002429_abnormal_blood_cell | 1.58480936 |
| 46 | MP0001845_abnormal_inflammatory_respons | 1.57236100 |
| 47 | MP0005310_abnormal_salivary_gland | 1.45283695 |
| 48 | MP0001545_abnormal_hematopoietic_system | 1.36626115 |
| 49 | MP0005397_hematopoietic_system_phenotyp | 1.36626115 |
| 50 | MP0001853_heart_inflammation | 1.36612588 |
| 51 | MP0005451_abnormal_body_composition | 1.33720733 |
| 52 | MP0008260_abnormal_autophagy | 1.27847883 |
| 53 | MP0002796_impaired_skin_barrier | 1.25588612 |
| 54 | MP0004808_abnormal_hematopoietic_stem | 1.22432502 |
| 55 | MP0008469_abnormal_protein_level | 1.22156381 |
| 56 | MP0008057_abnormal_DNA_replication | 1.18326873 |
| 57 | MP0000858_altered_metastatic_potential | 1.17594626 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 1.17358302 |
| 59 | MP0001764_abnormal_homeostasis | 1.14490280 |
| 60 | MP0001533_abnormal_skeleton_physiology | 1.13479952 |
| 61 | MP0005166_decreased_susceptibility_to | 1.12462735 |
| 62 | MP0003656_abnormal_erythrocyte_physiolo | 1.00745708 |
| 63 | MP0002998_abnormal_bone_remodeling | 0.98027801 |
| 64 | MP0004264_abnormal_extraembryonic_tissu | 0.97578095 |
| 65 | MP0009763_increased_sensitivity_to | 0.87251675 |
| 66 | MP0002019_abnormal_tumor_incidence | 0.83803620 |
| 67 | MP0000490_abnormal_crypts_of | 0.83242662 |
| 68 | MP0009278_abnormal_bone_marrow | 0.81604101 |
| 69 | MP0003172_abnormal_lysosome_physiology | 0.80702299 |
| 70 | MP0001663_abnormal_digestive_system | 0.80109203 |
| 71 | MP0001348_abnormal_lacrimal_gland | 0.79703181 |
| 72 | MP0005164_abnormal_response_to | 0.73209153 |
| 73 | MP0000604_amyloidosis | 0.71881061 |
| 74 | MP0008004_abnormal_stomach_pH | 0.71790891 |
| 75 | MP0008874_decreased_physiological_sensi | 0.70236371 |
| 76 | MP0002163_abnormal_gland_morphology | 0.69738327 |
| 77 | MP0005501_abnormal_skin_physiology | 0.68662822 |
| 78 | MP0005360_urolithiasis | 0.67707295 |
| 79 | MP0004510_myositis | 0.66543233 |
| 80 | MP0009764_decreased_sensitivity_to | 0.66159048 |
| 81 | MP0003191_abnormal_cellular_cholesterol | 0.65240362 |
| 82 | MP0002693_abnormal_pancreas_physiology | 0.65007317 |
| 83 | MP0003183_abnormal_peptide_metabolism | 0.64431373 |
| 84 | MP0003448_altered_tumor_morphology | 0.63935636 |
| 85 | MP0002136_abnormal_kidney_physiology | 0.63557684 |
| 86 | MP0008873_increased_physiological_sensi | 0.63472339 |
| 87 | MP0000249_abnormal_blood_vessel | 0.61827265 |
| 88 | MP0005408_hypopigmentation | 0.60935134 |
| 89 | MP0003806_abnormal_nucleotide_metabolis | 0.60518076 |
| 90 | MP0008872_abnormal_physiological_respon | 0.60075724 |
| 91 | MP0002332_abnormal_exercise_endurance | 0.59712980 |
| 92 | MP0000609_abnormal_liver_physiology | 0.57252452 |
| 93 | MP0000598_abnormal_liver_morphology | 0.57130623 |
| 94 | MP0001765_abnormal_ion_homeostasis | 0.53431438 |
| 95 | MP0005645_abnormal_hypothalamus_physiol | 0.52557429 |
| 96 | MP0004883_abnormal_blood_vessel | 0.52395281 |
| 97 | MP0009643_abnormal_urine_homeostasis | 0.51990958 |
| 98 | MP0001501_abnormal_sleep_pattern | 0.49985011 |
| 99 | MP0005376_homeostasis/metabolism_phenot | 0.46693386 |
| 100 | MP0000367_abnormal_coat/_hair | 0.46674935 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.83228246 |
| 2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.23834996 |
| 3 | T lymphocytopenia (HP:0005403) | 5.10558690 |
| 4 | Abnormality of T cell number (HP:0011839) | 5.00899465 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 5.00726489 |
| 6 | Myositis (HP:0100614) | 4.57201648 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 4.51880031 |
| 8 | Eczematoid dermatitis (HP:0000976) | 4.48314507 |
| 9 | Mediastinal lymphadenopathy (HP:0100721) | 4.30960137 |
| 10 | Abnormality of T cells (HP:0002843) | 4.10446735 |
| 11 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.96096456 |
| 12 | Orchitis (HP:0100796) | 3.83437197 |
| 13 | Joint swelling (HP:0001386) | 3.83123371 |
| 14 | Recurrent abscess formation (HP:0002722) | 3.80337169 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 3.69509492 |
| 16 | Retrobulbar optic neuritis (HP:0100654) | 3.68119445 |
| 17 | Optic neuritis (HP:0100653) | 3.68119445 |
| 18 | Increased IgM level (HP:0003496) | 3.59158117 |
| 19 | Panhypogammaglobulinemia (HP:0003139) | 3.57475772 |
| 20 | Recurrent fungal infections (HP:0002841) | 3.57029839 |
| 21 | Keratoconjunctivitis sicca (HP:0001097) | 3.33714906 |
| 22 | IgG deficiency (HP:0004315) | 3.29742550 |
| 23 | Encephalitis (HP:0002383) | 3.23828076 |
| 24 | Abnormality of macrophages (HP:0004311) | 3.23680504 |
| 25 | Prolonged bleeding time (HP:0003010) | 3.23334294 |
| 26 | Meningitis (HP:0001287) | 3.22554249 |
| 27 | Recurrent viral infections (HP:0004429) | 3.20103758 |
| 28 | Abnormality of T cell physiology (HP:0011840) | 3.19613680 |
| 29 | Pustule (HP:0200039) | 3.16884291 |
| 30 | Recurrent skin infections (HP:0001581) | 3.16527340 |
| 31 | Abnormality of eosinophils (HP:0001879) | 3.08009679 |
| 32 | Keratoconjunctivitis (HP:0001096) | 3.07125391 |
| 33 | Granulocytopenia (HP:0001913) | 3.06591903 |
| 34 | Vasculitis (HP:0002633) | 2.99241274 |
| 35 | Recurrent cutaneous fungal infections (HP:0011370) | 2.96148674 |
| 36 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.96148674 |
| 37 | Pulmonary infiltrates (HP:0002113) | 2.94162618 |
| 38 | Eosinophilia (HP:0001880) | 2.94028494 |
| 39 | Leukocytosis (HP:0001974) | 2.93780297 |
| 40 | Recurrent bronchitis (HP:0002837) | 2.92313632 |
| 41 | IgM deficiency (HP:0002850) | 2.89351417 |
| 42 | Obstructive lung disease (HP:0006536) | 2.87025336 |
| 43 | Chronic obstructive pulmonary disease (HP:0006510) | 2.87025336 |
| 44 | Combined immunodeficiency (HP:0005387) | 2.81380311 |
| 45 | Gastrointestinal infarctions (HP:0005244) | 2.67999096 |
| 46 | Abnormality of the prostate (HP:0008775) | 2.65655261 |
| 47 | Lymphopenia (HP:0001888) | 2.63139888 |
| 48 | Inflammation of the large intestine (HP:0002037) | 2.60416182 |
| 49 | Spontaneous hematomas (HP:0007420) | 2.59665487 |
| 50 | Gastrointestinal inflammation (HP:0004386) | 2.58297825 |
| 51 | Abnormality of the pleura (HP:0002103) | 2.57572005 |
| 52 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.55885378 |
| 53 | Epistaxis (HP:0000421) | 2.55779984 |
| 54 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.49078039 |
| 55 | Chest pain (HP:0100749) | 2.48985820 |
| 56 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.48314013 |
| 57 | Urticaria (HP:0001025) | 2.47495768 |
| 58 | Agammaglobulinemia (HP:0004432) | 2.47470571 |
| 59 | Chronic diarrhea (HP:0002028) | 2.47291032 |
| 60 | Increased serum ferritin (HP:0003281) | 2.45594906 |
| 61 | Thyroiditis (HP:0100646) | 2.41894045 |
| 62 | Gingival bleeding (HP:0000225) | 2.41594245 |
| 63 | Hemoptysis (HP:0002105) | 2.39890339 |
| 64 | Abnormality of dental color (HP:0011073) | 2.39629153 |
| 65 | Skin rash (HP:0000988) | 2.38445051 |
| 66 | Hypochromic anemia (HP:0001931) | 2.38311373 |
| 67 | Increased IgE level (HP:0003212) | 2.36929135 |
| 68 | Pulmonary embolism (HP:0002204) | 2.26201146 |
| 69 | Petechiae (HP:0000967) | 2.24343486 |
| 70 | Abnormality of iron homeostasis (HP:0011031) | 2.21943250 |
| 71 | Oral leukoplakia (HP:0002745) | 2.21723708 |
| 72 | Hypergammaglobulinemia (HP:0010702) | 2.21264840 |
| 73 | Lymphoma (HP:0002665) | 2.20633586 |
| 74 | Fatigue (HP:0012378) | 2.19997890 |
| 75 | Papilledema (HP:0001085) | 2.19591192 |
| 76 | Abnormality of the pericardium (HP:0001697) | 2.18073583 |
| 77 | Abnormality of B cell number (HP:0010975) | 2.14614211 |
| 78 | Anorexia (HP:0002039) | 2.12081523 |
| 79 | Alveolar cell carcinoma (HP:0006519) | 2.11144348 |
| 80 | Chronic otitis media (HP:0000389) | 2.09198673 |
| 81 | Papilloma (HP:0012740) | 2.07483352 |
| 82 | Verrucae (HP:0200043) | 2.07483352 |
| 83 | Gingivitis (HP:0000230) | 2.07135643 |
| 84 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.05118718 |
| 85 | Glucose intolerance (HP:0000833) | 2.05009756 |
| 86 | Gangrene (HP:0100758) | 2.03761277 |
| 87 | Hematochezia (HP:0002573) | 2.03417704 |
| 88 | Microcytic anemia (HP:0001935) | 2.02271868 |
| 89 | Hepatitis (HP:0012115) | 2.02196209 |
| 90 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.01928540 |
| 91 | B lymphocytopenia (HP:0010976) | 2.01462576 |
| 92 | Polycythemia (HP:0001901) | 1.98790720 |
| 93 | Abnormality of the frontal sinuses (HP:0002687) | 1.98141840 |
| 94 | Abnormality of male internal genitalia (HP:0000022) | 1.97304182 |
| 95 | Abnormality of the fingertips (HP:0001211) | 1.95781947 |
| 96 | Autoimmune thrombocytopenia (HP:0001973) | 1.94665730 |
| 97 | Hypochromic microcytic anemia (HP:0004840) | 1.93076566 |
| 98 | Polyneuropathy (HP:0001271) | 1.92811155 |
| 99 | Hypoplasia of the thymus (HP:0000778) | 1.91827494 |
| 100 | Skin ulcer (HP:0200042) | 1.89564730 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.22205518 |
| 2 | MST4 | 4.89614199 |
| 3 | MAP4K1 | 4.48344118 |
| 4 | ITK | 2.74857427 |
| 5 | SIK3 | 2.40235532 |
| 6 | TYK2 | 2.33184849 |
| 7 | ZAP70 | 2.28197995 |
| 8 | TAOK3 | 2.25477773 |
| 9 | BTK | 2.19964056 |
| 10 | GRK6 | 2.14244486 |
| 11 | TEC | 2.09546413 |
| 12 | CAMKK2 | 2.08240575 |
| 13 | FES | 2.04387292 |
| 14 | IKBKE | 2.02332460 |
| 15 | PRPF4B | 1.91119099 |
| 16 | CSK | 1.85601303 |
| 17 | NLK | 1.83244345 |
| 18 | RIPK4 | 1.81709683 |
| 19 | JAK3 | 1.80390379 |
| 20 | PASK | 1.76774160 |
| 21 | LCK | 1.72103330 |
| 22 | ERN1 | 1.67664583 |
| 23 | STK10 | 1.61270894 |
| 24 | MAP3K13 | 1.52724422 |
| 25 | SYK | 1.46168328 |
| 26 | HCK | 1.45084383 |
| 27 | FGFR4 | 1.34346635 |
| 28 | PRKCQ | 1.33926209 |
| 29 | MAP3K14 | 1.31653758 |
| 30 | JAK1 | 1.28364350 |
| 31 | MARK3 | 1.28338562 |
| 32 | TNK2 | 1.27371791 |
| 33 | PIM2 | 1.26435937 |
| 34 | PIM1 | 1.25938868 |
| 35 | CAMKK1 | 1.25797751 |
| 36 | TESK1 | 1.24055804 |
| 37 | LRRK2 | 1.23825197 |
| 38 | IKBKB | 1.22259194 |
| 39 | MAP3K3 | 1.15264117 |
| 40 | LYN | 1.14457811 |
| 41 | RAF1 | 1.09529862 |
| 42 | NEK6 | 1.04023331 |
| 43 | IRAK4 | 1.02648281 |
| 44 | EPHB1 | 1.02203827 |
| 45 | SIK2 | 1.01594657 |
| 46 | TAOK2 | 1.00178316 |
| 47 | FGFR3 | 0.97777891 |
| 48 | KDR | 0.96224723 |
| 49 | SMG1 | 0.93722374 |
| 50 | TBK1 | 0.93712708 |
| 51 | BLK | 0.92725666 |
| 52 | JAK2 | 0.90228034 |
| 53 | HIPK2 | 0.86670604 |
| 54 | MAP2K3 | 0.86574784 |
| 55 | SIK1 | 0.86084221 |
| 56 | MAP3K11 | 0.82651480 |
| 57 | TAOK1 | 0.81075522 |
| 58 | KIT | 0.78379432 |
| 59 | SCYL2 | 0.78147348 |
| 60 | CSF1R | 0.71248917 |
| 61 | YES1 | 0.65917597 |
| 62 | MAP3K10 | 0.64866159 |
| 63 | MAPK11 | 0.64053500 |
| 64 | MAP3K7 | 0.61319167 |
| 65 | MAPK7 | 0.59667800 |
| 66 | CDK4 | 0.58611144 |
| 67 | VRK2 | 0.57723988 |
| 68 | MARK2 | 0.57188646 |
| 69 | CDK6 | 0.55442044 |
| 70 | MAPK12 | 0.54462163 |
| 71 | MAP3K1 | 0.54120909 |
| 72 | TGFBR2 | 0.47649831 |
| 73 | PDK1 | 0.47232187 |
| 74 | CLK1 | 0.45858062 |
| 75 | FYN | 0.45153822 |
| 76 | PTK6 | 0.44490686 |
| 77 | MAPK3 | 0.41342937 |
| 78 | CDK9 | 0.41238736 |
| 79 | PIK3CA | 0.39439011 |
| 80 | MAPKAPK2 | 0.37681899 |
| 81 | NME1 | 0.35208255 |
| 82 | NUAK1 | 0.33249748 |
| 83 | PDGFRB | 0.32739285 |
| 84 | EIF2AK3 | 0.32637711 |
| 85 | ARAF | 0.32000536 |
| 86 | CHUK | 0.31838594 |
| 87 | STK38 | 0.30836715 |
| 88 | CDK19 | 0.29425216 |
| 89 | ADRBK1 | 0.27981662 |
| 90 | EPHA3 | 0.27788064 |
| 91 | PRKCI | 0.27588144 |
| 92 | TYRO3 | 0.26449969 |
| 93 | PRKCD | 0.26449421 |
| 94 | MAP3K12 | 0.25839695 |
| 95 | PIK3CG | 0.25054273 |
| 96 | EGFR | 0.24582308 |
| 97 | ABL1 | 0.23652666 |
| 98 | TAF1 | 0.21424698 |
| 99 | DYRK1B | 0.20674790 |
| 100 | MAP3K8 | 0.19961341 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.53662221 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.29661813 |
| 3 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.18734631 |
| 4 | Measles_Homo sapiens_hsa05162 | 2.93040042 |
| 5 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.78987572 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.67273484 |
| 7 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.56860856 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.48679607 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.44278329 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.37728937 |
| 11 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.23329182 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.08814649 |
| 13 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.01361345 |
| 14 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.96336526 |
| 15 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.94481978 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.85886266 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.84382585 |
| 18 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.78573113 |
| 19 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.68156010 |
| 20 | Legionellosis_Homo sapiens_hsa05134 | 1.65523075 |
| 21 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.65343193 |
| 22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.63501550 |
| 23 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.62385822 |
| 24 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.62365066 |
| 25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.60736944 |
| 26 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.59414861 |
| 27 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.57255772 |
| 28 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.53752517 |
| 29 | Hepatitis B_Homo sapiens_hsa05161 | 1.52668207 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.51535708 |
| 31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.50394079 |
| 32 | Viral myocarditis_Homo sapiens_hsa05416 | 1.38563231 |
| 33 | Influenza A_Homo sapiens_hsa05164 | 1.34880306 |
| 34 | Pertussis_Homo sapiens_hsa05133 | 1.34687357 |
| 35 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.15489075 |
| 36 | Tuberculosis_Homo sapiens_hsa05152 | 1.15349868 |
| 37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.13361714 |
| 38 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.13245123 |
| 39 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.11479415 |
| 40 | Thyroid cancer_Homo sapiens_hsa05216 | 1.08155762 |
| 41 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.02062229 |
| 42 | Apoptosis_Homo sapiens_hsa04210 | 1.00761184 |
| 43 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.98652483 |
| 44 | HTLV-I infection_Homo sapiens_hsa05166 | 0.96261355 |
| 45 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.95765202 |
| 46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.93908074 |
| 47 | Salmonella infection_Homo sapiens_hsa05132 | 0.93778553 |
| 48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.92829808 |
| 49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.91053451 |
| 50 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.90283556 |
| 51 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.87433680 |
| 52 | Ribosome_Homo sapiens_hsa03010 | 0.87271944 |
| 53 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.84501385 |
| 54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.84431995 |
| 55 | Hepatitis C_Homo sapiens_hsa05160 | 0.84265199 |
| 56 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.81918767 |
| 57 | Prion diseases_Homo sapiens_hsa05020 | 0.81430961 |
| 58 | Colorectal cancer_Homo sapiens_hsa05210 | 0.81035462 |
| 59 | Platelet activation_Homo sapiens_hsa04611 | 0.76308000 |
| 60 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.74695999 |
| 61 | Shigellosis_Homo sapiens_hsa05131 | 0.61020219 |
| 62 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.60271766 |
| 63 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.60213454 |
| 64 | Endometrial cancer_Homo sapiens_hsa05213 | 0.59891930 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.56452641 |
| 66 | Amoebiasis_Homo sapiens_hsa05146 | 0.55755968 |
| 67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55685324 |
| 68 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.55346881 |
| 69 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.54869894 |
| 70 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.52907354 |
| 71 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.52387718 |
| 72 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.50167665 |
| 73 | Endocytosis_Homo sapiens_hsa04144 | 0.49381829 |
| 74 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.48478868 |
| 75 | Insulin resistance_Homo sapiens_hsa04931 | 0.48398494 |
| 76 | Circadian rhythm_Homo sapiens_hsa04710 | 0.47205493 |
| 77 | Sulfur relay system_Homo sapiens_hsa04122 | 0.45373582 |
| 78 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.43163494 |
| 79 | Other glycan degradation_Homo sapiens_hsa00511 | 0.42873563 |
| 80 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.41965087 |
| 81 | Asthma_Homo sapiens_hsa05310 | 0.39652037 |
| 82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37330118 |
| 83 | Prostate cancer_Homo sapiens_hsa05215 | 0.36363814 |
| 84 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.35869912 |
| 85 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.33390578 |
| 86 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32036466 |
| 87 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.31128831 |
| 88 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.30543355 |
| 89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26280688 |
| 90 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.25988019 |
| 91 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.25845363 |
| 92 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.23432610 |
| 93 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.21261869 |
| 94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.20512128 |
| 95 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.19965608 |
| 96 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.19737351 |
| 97 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.19007715 |
| 98 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.19000644 |
| 99 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.19000465 |
| 100 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.18296927 |

