

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | tolerance induction (GO:0002507) | 9.64936478 |
| 2 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 9.40055643 |
| 3 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 8.51022089 |
| 4 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 8.48498194 |
| 5 | negative regulation of glycogen biosynthetic process (GO:0045719) | 8.40871294 |
| 6 | galactose catabolic process (GO:0019388) | 8.27680207 |
| 7 | N-terminal protein amino acid acetylation (GO:0006474) | 8.27482290 |
| 8 | regulation of oxidative stress-induced neuron death (GO:1903203) | 8.22859315 |
| 9 | interleukin-6-mediated signaling pathway (GO:0070102) | 8.13481475 |
| 10 | negative regulation of muscle hypertrophy (GO:0014741) | 7.69482011 |
| 11 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 7.64690408 |
| 12 | regulation of energy homeostasis (GO:2000505) | 7.31098139 |
| 13 | membrane tubulation (GO:0097320) | 6.81643364 |
| 14 | protein localization to endosome (GO:0036010) | 6.72814131 |
| 15 | negative regulation of glycogen metabolic process (GO:0070874) | 6.72384983 |
| 16 | cellular response to interleukin-6 (GO:0071354) | 6.53293795 |
| 17 | regulation of cellular respiration (GO:0043457) | 5.77051344 |
| 18 | ribosomal small subunit biogenesis (GO:0042274) | 5.68197887 |
| 19 | viral transcription (GO:0019083) | 5.45842080 |
| 20 | response to interleukin-6 (GO:0070741) | 5.30923488 |
| 21 | regulation of vitamin D biosynthetic process (GO:0060556) | 5.22714254 |
| 22 | cysteine metabolic process (GO:0006534) | 5.20064494 |
| 23 | translational termination (GO:0006415) | 5.11749601 |
| 24 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.94538610 |
| 25 | galactose metabolic process (GO:0006012) | 4.63394658 |
| 26 | negative thymic T cell selection (GO:0045060) | 4.49761371 |
| 27 | forebrain morphogenesis (GO:0048853) | 4.40573142 |
| 28 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.39723531 |
| 29 | viral life cycle (GO:0019058) | 4.36885155 |
| 30 | negative T cell selection (GO:0043383) | 4.34247436 |
| 31 | N-terminal protein amino acid modification (GO:0031365) | 4.30984957 |
| 32 | protein heterotetramerization (GO:0051290) | 4.29377562 |
| 33 | sequestering of actin monomers (GO:0042989) | 4.26525232 |
| 34 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.25779608 |
| 35 | regulation of vitamin metabolic process (GO:0030656) | 4.21949922 |
| 36 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.16413562 |
| 37 | lymph node development (GO:0048535) | 4.14855340 |
| 38 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.09399565 |
| 39 | megakaryocyte development (GO:0035855) | 4.08328423 |
| 40 | cotranslational protein targeting to membrane (GO:0006613) | 4.07308726 |
| 41 | response to nitrosative stress (GO:0051409) | 4.06387517 |
| 42 | ubiquinone biosynthetic process (GO:0006744) | 4.05057004 |
| 43 | protein targeting to ER (GO:0045047) | 4.02141769 |
| 44 | translational elongation (GO:0006414) | 3.99574225 |
| 45 | positive regulation of T cell apoptotic process (GO:0070234) | 3.93571074 |
| 46 | regulation of hypersensitivity (GO:0002883) | 3.91325323 |
| 47 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.82111149 |
| 48 | cellular protein complex disassembly (GO:0043624) | 3.78130513 |
| 49 | ribosome biogenesis (GO:0042254) | 3.78094387 |
| 50 | protein localization to endoplasmic reticulum (GO:0070972) | 3.71467269 |
| 51 | ribosomal large subunit biogenesis (GO:0042273) | 3.69943894 |
| 52 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.64230228 |
| 53 | negative regulation of T cell mediated immunity (GO:0002710) | 3.61663221 |
| 54 | negative regulation of potassium ion transport (GO:0043267) | 3.61326258 |
| 55 | regulation of gamma-delta T cell activation (GO:0046643) | 3.60823319 |
| 56 | ubiquinone metabolic process (GO:0006743) | 3.57336291 |
| 57 | regulation of the force of heart contraction (GO:0002026) | 3.56517996 |
| 58 | superoxide anion generation (GO:0042554) | 3.53085568 |
| 59 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.52817504 |
| 60 | regulation of mitochondrial fission (GO:0090140) | 3.49949707 |
| 61 | regulation of chromatin binding (GO:0035561) | 3.49727625 |
| 62 | negative regulation of monooxygenase activity (GO:0032769) | 3.43872009 |
| 63 | ribosomal small subunit assembly (GO:0000028) | 3.43414483 |
| 64 | positive regulation of positive chemotaxis (GO:0050927) | 3.42966965 |
| 65 | positive regulation of interleukin-12 production (GO:0032735) | 3.42464690 |
| 66 | spermatid nucleus differentiation (GO:0007289) | 3.42355423 |
| 67 | quinone biosynthetic process (GO:1901663) | 3.41707276 |
| 68 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.35263920 |
| 69 | Peyers patch development (GO:0048541) | 3.35263920 |
| 70 | chemokine-mediated signaling pathway (GO:0070098) | 3.34902203 |
| 71 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.34001923 |
| 72 | L-phenylalanine catabolic process (GO:0006559) | 3.34001923 |
| 73 | cytokine secretion (GO:0050663) | 3.29962024 |
| 74 | regulation of positive chemotaxis (GO:0050926) | 3.29706658 |
| 75 | mast cell activation (GO:0045576) | 3.28368089 |
| 76 | tyrosine metabolic process (GO:0006570) | 3.26797518 |
| 77 | valine metabolic process (GO:0006573) | 3.21490179 |
| 78 | mRNA modification (GO:0016556) | 3.18887208 |
| 79 | regulation of cardiac muscle hypertrophy (GO:0010611) | 3.18543612 |
| 80 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.16590231 |
| 81 | protein complex disassembly (GO:0043241) | 3.12105008 |
| 82 | thymic T cell selection (GO:0045061) | 3.11513088 |
| 83 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.08073178 |
| 84 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.08073178 |
| 85 | regulation of muscle hypertrophy (GO:0014743) | 3.08065008 |
| 86 | negative regulation of cell killing (GO:0031342) | 3.07892968 |
| 87 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.07892968 |
| 88 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.03974360 |
| 89 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.03459381 |
| 90 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.02984971 |
| 91 | erythrocyte maturation (GO:0043249) | 3.02916045 |
| 92 | regulation of mitochondrial depolarization (GO:0051900) | 3.01182061 |
| 93 | regulation of respiratory gaseous exchange (GO:0043576) | 3.00076388 |
| 94 | endoderm formation (GO:0001706) | 3.00047189 |
| 95 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.97822055 |
| 96 | interkinetic nuclear migration (GO:0022027) | 2.95907503 |
| 97 | regulation of interleukin-12 production (GO:0032655) | 2.91204388 |
| 98 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.88986290 |
| 99 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.88986290 |
| 100 | respiratory chain complex IV assembly (GO:0008535) | 2.88438858 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 7.73534278 |
| 2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.99212351 |
| 3 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 3.81391328 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.49644270 |
| 5 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.25843811 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.09819812 |
| 7 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.93663999 |
| 8 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.93663999 |
| 9 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.93663999 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.76489275 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.73966153 |
| 12 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.71819058 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.69271510 |
| 14 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.61588604 |
| 15 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.58885092 |
| 16 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.14453238 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.13222414 |
| 18 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.03782573 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.97641797 |
| 20 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.91096651 |
| 21 | SPI1_23127762_ChIP-Seq_K562_Human | 1.87820560 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.87398964 |
| 23 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.86138544 |
| 24 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.85490184 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.81911889 |
| 26 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.73819109 |
| 27 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.71200697 |
| 28 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.64411884 |
| 29 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.64369475 |
| 30 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.64319187 |
| 31 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.64202730 |
| 32 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.63995642 |
| 33 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.60476229 |
| 34 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.54868478 |
| 35 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.53152266 |
| 36 | UTX_26944678_Chip-Seq_JUKART_Human | 1.51567471 |
| 37 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.43789105 |
| 38 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.42192926 |
| 39 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.41766680 |
| 40 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.39031391 |
| 41 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.37659297 |
| 42 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.37133522 |
| 43 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.33512863 |
| 44 | MAF_26560356_Chip-Seq_TH2_Human | 1.28935389 |
| 45 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.26079257 |
| 46 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.25527888 |
| 47 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.24047595 |
| 48 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.23818955 |
| 49 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.22023352 |
| 50 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18523728 |
| 51 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.16077915 |
| 52 | MYB_26560356_Chip-Seq_TH2_Human | 1.15544438 |
| 53 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.15076877 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14785663 |
| 55 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.14036541 |
| 56 | MAF_26560356_Chip-Seq_TH1_Human | 1.13668459 |
| 57 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11351243 |
| 58 | GATA3_26560356_Chip-Seq_TH2_Human | 1.11084701 |
| 59 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.10607104 |
| 60 | MYB_26560356_Chip-Seq_TH1_Human | 1.07226880 |
| 61 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.05667170 |
| 62 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.05288631 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.04692613 |
| 64 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.04127643 |
| 65 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.02768585 |
| 66 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.01389158 |
| 67 | SA1_27219007_Chip-Seq_Bcells_Human | 1.00935497 |
| 68 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.98424802 |
| 69 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97794465 |
| 70 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.97768458 |
| 71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.97668035 |
| 72 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.95830366 |
| 73 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.95314926 |
| 74 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.94979026 |
| 75 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94676191 |
| 76 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.94549991 |
| 77 | P300_27268052_Chip-Seq_Bcells_Human | 0.93400172 |
| 78 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.93378566 |
| 79 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92123316 |
| 80 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.91433482 |
| 81 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.91248436 |
| 82 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.89911339 |
| 83 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.89128897 |
| 84 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.87558014 |
| 85 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.86940411 |
| 86 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.86683535 |
| 87 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.85127318 |
| 88 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.84880626 |
| 89 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.83389564 |
| 90 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.80242876 |
| 91 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.78872101 |
| 92 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.78061126 |
| 93 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.76865206 |
| 94 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.76534346 |
| 95 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76190960 |
| 96 | GF1_26923725_Chip-Seq_HPCs_Mouse | 0.75827765 |
| 97 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.75531424 |
| 98 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.74978591 |
| 99 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.74907128 |
| 100 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.74190029 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002653_abnormal_ependyma_morphology | 5.69234252 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 5.31177995 |
| 3 | MP0005623_abnormal_meninges_morphology | 4.48744236 |
| 4 | MP0004084_abnormal_cardiac_muscle | 4.19230335 |
| 5 | MP0003279_aneurysm | 3.71323663 |
| 6 | MP0001915_intracranial_hemorrhage | 3.43644598 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.44887851 |
| 8 | MP0003300_gastrointestinal_ulcer | 2.35469121 |
| 9 | MP0009379_abnormal_foot_pigmentation | 2.31241910 |
| 10 | MP0004036_abnormal_muscle_relaxation | 2.29613157 |
| 11 | MP0006054_spinal_hemorrhage | 10.8231735 |
| 12 | MP0001800_abnormal_humoral_immune | 1.97317870 |
| 13 | MP0009333_abnormal_splenocyte_physiolog | 1.93891308 |
| 14 | MP0001986_abnormal_taste_sensitivity | 1.86825748 |
| 15 | MP0004215_abnormal_myocardial_fiber | 1.79314580 |
| 16 | MP0004130_abnormal_muscle_cell | 1.78358112 |
| 17 | MP0010155_abnormal_intestine_physiology | 1.67731799 |
| 18 | MP0009785_altered_susceptibility_to | 1.65541376 |
| 19 | MP0004484_altered_response_of | 1.62262981 |
| 20 | MP0002163_abnormal_gland_morphology | 1.59172120 |
| 21 | MP0003303_peritoneal_inflammation | 1.57195449 |
| 22 | MP0000465_gastrointestinal_hemorrhage | 1.57070351 |
| 23 | MP0005671_abnormal_response_to | 1.52215466 |
| 24 | MP0002723_abnormal_immune_serum | 1.51303292 |
| 25 | MP0001348_abnormal_lacrimal_gland | 1.45859899 |
| 26 | MP0009765_abnormal_xenobiotic_induced | 1.42178552 |
| 27 | MP0000767_abnormal_smooth_muscle | 1.32764454 |
| 28 | MP0000703_abnormal_thymus_morphology | 1.27890730 |
| 29 | MP0005220_abnormal_exocrine_pancreas | 1.26008320 |
| 30 | MP0003186_abnormal_redox_activity | 1.24452660 |
| 31 | MP0003763_abnormal_thymus_physiology | 1.23960665 |
| 32 | MP0001835_abnormal_antigen_presentation | 1.22593777 |
| 33 | MP0004742_abnormal_vestibular_system | 1.20861266 |
| 34 | MP0000685_abnormal_immune_system | 1.20374909 |
| 35 | MP0002452_abnormal_antigen_presenting | 1.18069994 |
| 36 | MP0003724_increased_susceptibility_to | 1.17935161 |
| 37 | MP0005000_abnormal_immune_tolerance | 1.17706738 |
| 38 | MP0002693_abnormal_pancreas_physiology | 1.15488424 |
| 39 | MP0009780_abnormal_chondrocyte_physiolo | 1.13883620 |
| 40 | MP0000678_abnormal_parathyroid_gland | 1.13835988 |
| 41 | MP0002420_abnormal_adaptive_immunity | 1.13431869 |
| 42 | MP0003633_abnormal_nervous_system | 1.13254841 |
| 43 | MP0002419_abnormal_innate_immunity | 1.11412791 |
| 44 | MP0001819_abnormal_immune_cell | 1.11199150 |
| 45 | MP0003866_abnormal_defecation | 1.10096067 |
| 46 | MP0005387_immune_system_phenotype | 1.08952228 |
| 47 | MP0001790_abnormal_immune_system | 1.08952228 |
| 48 | MP0001764_abnormal_homeostasis | 1.07543472 |
| 49 | MP0001845_abnormal_inflammatory_respons | 1.06247460 |
| 50 | MP0003195_calcinosis | 1.04287071 |
| 51 | MP0002398_abnormal_bone_marrow | 1.04074300 |
| 52 | MP0001346_abnormal_lacrimal_gland | 1.03651919 |
| 53 | MP0000569_abnormal_digit_pigmentation | 0.99955188 |
| 54 | MP0002722_abnormal_immune_system | 0.99392056 |
| 55 | MP0005025_abnormal_response_to | 0.99252839 |
| 56 | MP0003183_abnormal_peptide_metabolism | 0.99046639 |
| 57 | MP0006292_abnormal_olfactory_placode | 0.96609165 |
| 58 | MP0000716_abnormal_immune_system | 0.94668853 |
| 59 | MP0005165_increased_susceptibility_to | 0.91589233 |
| 60 | MP0000689_abnormal_spleen_morphology | 0.89154247 |
| 61 | MP0001873_stomach_inflammation | 0.87612667 |
| 62 | MP0005379_endocrine/exocrine_gland_phen | 0.86917414 |
| 63 | MP0003631_nervous_system_phenotype | 0.85132748 |
| 64 | MP0000516_abnormal_urinary_system | 0.82559314 |
| 65 | MP0005367_renal/urinary_system_phenotyp | 0.82559314 |
| 66 | MP0002405_respiratory_system_inflammati | 0.80195184 |
| 67 | MP0001661_extended_life_span | 0.78753602 |
| 68 | MP0003646_muscle_fatigue | 0.77506199 |
| 69 | MP0002148_abnormal_hypersensitivity_rea | 0.76493938 |
| 70 | MP0002429_abnormal_blood_cell | 0.75641017 |
| 71 | MP0005448_abnormal_energy_balance | 0.73141980 |
| 72 | MP0008775_abnormal_heart_ventricle | 0.72753841 |
| 73 | MP0005266_abnormal_metabolism | 0.71411900 |
| 74 | MP0009763_increased_sensitivity_to | 0.67301445 |
| 75 | MP0005376_homeostasis/metabolism_phenot | 0.63925012 |
| 76 | MP0009250_abnormal_appendicular_skeleto | 0.63547889 |
| 77 | MP0001544_abnormal_cardiovascular_syste | 0.61657483 |
| 78 | MP0005385_cardiovascular_system_phenoty | 0.61657483 |
| 79 | MP0005334_abnormal_fat_pad | 0.61461820 |
| 80 | MP0006082_CNS_inflammation | 0.61411104 |
| 81 | MP0001501_abnormal_sleep_pattern | 0.60574711 |
| 82 | MP0003567_abnormal_fetal_cardiomyocyte | 0.55560025 |
| 83 | MP0003011_delayed_dark_adaptation | 0.55528733 |
| 84 | MP0008469_abnormal_protein_level | 0.53499264 |
| 85 | MP0004381_abnormal_hair_follicle | 0.53192439 |
| 86 | MP0001340_abnormal_eyelid_morphology | 0.50603521 |
| 87 | MP0002972_abnormal_cardiac_muscle | 0.49803337 |
| 88 | MP0002896_abnormal_bone_mineralization | 0.47657984 |
| 89 | MP0002106_abnormal_muscle_physiology | 0.47260716 |
| 90 | MP0000609_abnormal_liver_physiology | 0.45701354 |
| 91 | MP0002277_abnormal_respiratory_mucosa | 0.45325811 |
| 92 | MP0005023_abnormal_wound_healing | 0.43882688 |
| 93 | MP0003252_abnormal_bile_duct | 0.42558751 |
| 94 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.42116911 |
| 95 | MP0000477_abnormal_intestine_morphology | 0.41952401 |
| 96 | MP0005647_abnormal_sex_gland | 0.41901374 |
| 97 | MP0003795_abnormal_bone_structure | 0.41706150 |
| 98 | MP0005197_abnormal_uvea_morphology | 0.41426658 |
| 99 | MP0001485_abnormal_pinna_reflex | 0.41420788 |
| 100 | MP0001286_abnormal_eye_development | 0.38165332 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Progressive inability to walk (HP:0002505) | 6.63356447 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 6.07316602 |
| 3 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.07316602 |
| 4 | Stomatitis (HP:0010280) | 5.61226032 |
| 5 | Loss of speech (HP:0002371) | 5.60459566 |
| 6 | Chronic otitis media (HP:0000389) | 5.57307984 |
| 7 | Mutism (HP:0002300) | 5.48711518 |
| 8 | Premature ovarian failure (HP:0008209) | 5.41635129 |
| 9 | Hypergonadotropic hypogonadism (HP:0000815) | 5.39737284 |
| 10 | Abnormal number of erythroid precursors (HP:0012131) | 4.95452605 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.44679926 |
| 12 | B lymphocytopenia (HP:0010976) | 4.41488699 |
| 13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.93102818 |
| 14 | Disinhibition (HP:0000734) | 3.90430231 |
| 15 | Abnormality of B cell number (HP:0010975) | 3.89448191 |
| 16 | Papilledema (HP:0001085) | 3.83852756 |
| 17 | Aortic regurgitation (HP:0001659) | 3.70511570 |
| 18 | Chronic sinusitis (HP:0011109) | 3.63737989 |
| 19 | Chronic diarrhea (HP:0002028) | 3.54316196 |
| 20 | Abnormal ciliary motility (HP:0012262) | 3.40384116 |
| 21 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.28723346 |
| 22 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.28723346 |
| 23 | Dyskinesia (HP:0100660) | 3.23590135 |
| 24 | Hepatocellular necrosis (HP:0001404) | 3.21640646 |
| 25 | Inability to walk (HP:0002540) | 3.09428324 |
| 26 | Pseudobulbar signs (HP:0002200) | 2.97986605 |
| 27 | Agammaglobulinemia (HP:0004432) | 2.91579604 |
| 28 | Enlarged epiphyses (HP:0010580) | 2.85160731 |
| 29 | Renal cortical cysts (HP:0000803) | 2.77623945 |
| 30 | Rhinitis (HP:0012384) | 2.61371492 |
| 31 | IgG deficiency (HP:0004315) | 2.59099736 |
| 32 | Increased IgM level (HP:0003496) | 2.58839597 |
| 33 | Sepsis (HP:0100806) | 2.55767876 |
| 34 | T lymphocytopenia (HP:0005403) | 2.54658142 |
| 35 | Elfin facies (HP:0004428) | 2.48491662 |
| 36 | Porencephaly (HP:0002132) | 2.47050949 |
| 37 | Thin bony cortex (HP:0002753) | 2.42970330 |
| 38 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.39378355 |
| 39 | Progressive muscle weakness (HP:0003323) | 2.39306573 |
| 40 | Cleft eyelid (HP:0000625) | 2.37207593 |
| 41 | Conical tooth (HP:0000698) | 2.33870636 |
| 42 | Acute necrotizing encephalopathy (HP:0006965) | 2.33153365 |
| 43 | Delayed epiphyseal ossification (HP:0002663) | 2.32958303 |
| 44 | Abnormality of T cell number (HP:0011839) | 2.27842038 |
| 45 | Progressive macrocephaly (HP:0004481) | 2.26777535 |
| 46 | Severe combined immunodeficiency (HP:0004430) | 2.26051606 |
| 47 | Mitral regurgitation (HP:0001653) | 2.22975329 |
| 48 | Hepatic necrosis (HP:0002605) | 2.20554993 |
| 49 | Widely patent fontanelles and sutures (HP:0004492) | 2.19545805 |
| 50 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.14249055 |
| 51 | Hypoplastic ischia (HP:0003175) | 2.12885139 |
| 52 | Personality changes (HP:0000751) | 2.11521012 |
| 53 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.09282885 |
| 54 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.08922232 |
| 55 | Mitochondrial inheritance (HP:0001427) | 2.04977652 |
| 56 | Bulbous nose (HP:0000414) | 2.02649925 |
| 57 | Thyroiditis (HP:0100646) | 2.02419290 |
| 58 | Abnormality of oral frenula (HP:0000190) | 2.01398312 |
| 59 | Renovascular hypertension (HP:0100817) | 2.00164388 |
| 60 | Abnormality of the costochondral junction (HP:0000919) | 2.00111351 |
| 61 | Chronic hepatic failure (HP:0100626) | 10.9088593 |
| 62 | Overriding aorta (HP:0002623) | 1.99980720 |
| 63 | Submucous cleft hard palate (HP:0000176) | 1.99181945 |
| 64 | Pallor (HP:0000980) | 1.97076852 |
| 65 | Abnormal foot bone ossification (HP:0010675) | 1.96965534 |
| 66 | Systemic lupus erythematosus (HP:0002725) | 1.95731653 |
| 67 | Leukodystrophy (HP:0002415) | 1.92569675 |
| 68 | Pustule (HP:0200039) | 1.91877964 |
| 69 | Stereotypic behavior (HP:0000733) | 1.91320964 |
| 70 | Pancytopenia (HP:0001876) | 1.90715173 |
| 71 | Flat cornea (HP:0007720) | 1.90630206 |
| 72 | Inappropriate behavior (HP:0000719) | 1.90126256 |
| 73 | Renal duplication (HP:0000075) | 1.88106596 |
| 74 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.83496339 |
| 75 | Hyperacusis (HP:0010780) | 1.80927687 |
| 76 | Macrocytic anemia (HP:0001972) | 1.79897065 |
| 77 | Posterior subcapsular cataract (HP:0007787) | 1.79702131 |
| 78 | Methylmalonic acidemia (HP:0002912) | 1.79583655 |
| 79 | Restlessness (HP:0000711) | 1.79391477 |
| 80 | Metabolic acidosis (HP:0001942) | 1.79054017 |
| 81 | Apathy (HP:0000741) | 1.77798479 |
| 82 | Optic disc pallor (HP:0000543) | 1.76876450 |
| 83 | Combined immunodeficiency (HP:0005387) | 1.76340079 |
| 84 | Abnormality of the ischium (HP:0003174) | 1.75490305 |
| 85 | Constricted visual fields (HP:0001133) | 1.73410036 |
| 86 | Granulocytopenia (HP:0001913) | 1.72976139 |
| 87 | Abnormality of the nasal septum (HP:0000419) | 1.72772999 |
| 88 | Acute encephalopathy (HP:0006846) | 1.72403348 |
| 89 | Lymphopenia (HP:0001888) | 1.72282031 |
| 90 | Glomerulonephritis (HP:0000099) | 1.72202776 |
| 91 | Adducted thumb (HP:0001181) | 1.72101965 |
| 92 | Retrobulbar optic neuritis (HP:0100654) | 1.71858413 |
| 93 | Optic neuritis (HP:0100653) | 1.71858413 |
| 94 | Trigonocephaly (HP:0000243) | 1.70650800 |
| 95 | Abnormal hemoglobin (HP:0011902) | 1.69945691 |
| 96 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.68550706 |
| 97 | Hypoplasia of the radius (HP:0002984) | 1.63739444 |
| 98 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.62630729 |
| 99 | Hypoplasia of the ulna (HP:0003022) | 1.62015457 |
| 100 | Increased hepatocellular lipid droplets (HP:0006565) | 1.59400327 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.26900172 |
| 2 | MAP3K13 | 5.63629485 |
| 3 | CAMKK1 | 5.08708701 |
| 4 | MAP4K1 | 4.86763045 |
| 5 | RIPK4 | 3.11112808 |
| 6 | MAP3K14 | 2.54591583 |
| 7 | SIK2 | 2.43617119 |
| 8 | CAMKK2 | 2.08602347 |
| 9 | PASK | 10.2454484 |
| 10 | LRRK2 | 1.94809969 |
| 11 | ZAP70 | 1.66310304 |
| 12 | SCYL2 | 1.66163191 |
| 13 | BRSK2 | 1.55300887 |
| 14 | BTK | 1.43711169 |
| 15 | JAK3 | 1.38295218 |
| 16 | TYRO3 | 1.18205544 |
| 17 | SYK | 1.18183631 |
| 18 | MAP3K7 | 0.96941699 |
| 19 | TEC | 0.92186583 |
| 20 | LCK | 0.86697692 |
| 21 | ITK | 0.86221000 |
| 22 | MARK3 | 0.79590233 |
| 23 | IKBKB | 0.75139513 |
| 24 | PRKCQ | 0.73779699 |
| 25 | STK4 | 0.72446892 |
| 26 | NEK9 | 0.65373327 |
| 27 | CHUK | 0.62889386 |
| 28 | PTK6 | 0.60835121 |
| 29 | LYN | 0.57154740 |
| 30 | ADRBK2 | 0.56676161 |
| 31 | HCK | 0.56438885 |
| 32 | MAPKAPK3 | 0.55441893 |
| 33 | PAK6 | 0.53827796 |
| 34 | FES | 0.52830706 |
| 35 | STK38 | 0.51281164 |
| 36 | BRSK1 | 0.48842648 |
| 37 | CLK1 | 0.45543463 |
| 38 | FGR | 0.44283147 |
| 39 | BMPR1B | 0.44229912 |
| 40 | YES1 | 0.43576986 |
| 41 | NEK2 | 0.43576394 |
| 42 | CSK | 0.39937147 |
| 43 | JAK2 | 0.37665811 |
| 44 | IKBKE | 0.34285128 |
| 45 | SGK494 | 0.33555810 |
| 46 | SGK223 | 0.33555810 |
| 47 | ACVR1B | 0.32729784 |
| 48 | PRKCZ | 0.32620956 |
| 49 | PRKAA2 | 0.31106058 |
| 50 | TNIK | 0.30964323 |
| 51 | MAP4K2 | 0.30654433 |
| 52 | SIK3 | 0.28872858 |
| 53 | TLK1 | 0.27528123 |
| 54 | STK11 | 0.26873763 |
| 55 | PRKCD | 0.24368440 |
| 56 | PIK3CG | 0.23879178 |
| 57 | KIT | 0.23523753 |
| 58 | GRK6 | 0.22673176 |
| 59 | DMPK | 0.20874184 |
| 60 | BLK | 0.20736999 |
| 61 | GRK1 | 0.20427636 |
| 62 | SGK1 | 0.20277183 |
| 63 | GRK7 | 0.19728034 |
| 64 | RPS6KA5 | 0.19318672 |
| 65 | JAK1 | 0.19059840 |
| 66 | PDK1 | 0.18668422 |
| 67 | IGF1R | 0.18446511 |
| 68 | OBSCN | 0.16894598 |
| 69 | MAPK11 | 0.16510201 |
| 70 | ADRBK1 | 0.15924188 |
| 71 | MAPK13 | 0.15322117 |
| 72 | DYRK2 | 0.14837858 |
| 73 | TGFBR1 | 0.14567819 |
| 74 | INSRR | 0.14394790 |
| 75 | PAK2 | 0.14083234 |
| 76 | FYN | 0.14030693 |
| 77 | PAK3 | 0.12389721 |
| 78 | TAF1 | 0.11800013 |
| 79 | MAPKAPK2 | 0.10396692 |
| 80 | MAPK12 | 0.10149033 |
| 81 | MUSK | 0.09706151 |
| 82 | MAP2K3 | 0.08782835 |
| 83 | RPS6KA4 | 0.08665676 |
| 84 | MAP2K6 | 0.07903864 |
| 85 | MKNK2 | 0.07660887 |
| 86 | PRKACG | 0.05728946 |
| 87 | PRKCA | 0.04145973 |
| 88 | KDR | 0.03970697 |
| 89 | PAK1 | 0.03344506 |
| 90 | FRK | 0.03133995 |
| 91 | SIK1 | 0.02937549 |
| 92 | RPS6KA3 | 0.02881957 |
| 93 | TYK2 | 0.02168125 |
| 94 | RPS6KA1 | 0.02128006 |
| 95 | STK10 | 0.01563707 |
| 96 | CSNK1G3 | 0.01259861 |
| 97 | MAPK14 | 0.01110987 |
| 98 | MAPK3 | 0.00582424 |
| 99 | SRC | 0.00572427 |
| 100 | CSNK2A2 | 0.00210376 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 5.41798749 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.08299965 |
| 3 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 3.00229668 |
| 4 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.82033216 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.45507570 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.44453892 |
| 7 | Galactose metabolism_Homo sapiens_hsa00052 | 2.42665741 |
| 8 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.29061633 |
| 9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.22246173 |
| 10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.22043543 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.21949588 |
| 12 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.15624929 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.10139283 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.07986518 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.03419122 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.96504753 |
| 17 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.91372637 |
| 18 | Asthma_Homo sapiens_hsa05310 | 1.81960686 |
| 19 | Cocaine addiction_Homo sapiens_hsa05030 | 1.69317384 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.66550020 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.63525510 |
| 22 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.54828449 |
| 23 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.47890258 |
| 24 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.46706255 |
| 25 | Measles_Homo sapiens_hsa05162 | 1.44180268 |
| 26 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.36013157 |
| 27 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.35722206 |
| 28 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.33104956 |
| 29 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.23658279 |
| 30 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.21924790 |
| 31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.21576078 |
| 32 | Viral myocarditis_Homo sapiens_hsa05416 | 1.21416599 |
| 33 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.21068663 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.20195197 |
| 35 | Long-term potentiation_Homo sapiens_hsa04720 | 1.17526762 |
| 36 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.13697128 |
| 37 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.12841796 |
| 38 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.04974149 |
| 39 | Hepatitis B_Homo sapiens_hsa05161 | 1.03337124 |
| 40 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.02350327 |
| 41 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.01605506 |
| 42 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.95417395 |
| 43 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.93219924 |
| 44 | Shigellosis_Homo sapiens_hsa05131 | 0.92513879 |
| 45 | Apoptosis_Homo sapiens_hsa04210 | 0.89195199 |
| 46 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.86384884 |
| 47 | Leishmaniasis_Homo sapiens_hsa05140 | 0.84573887 |
| 48 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.82741289 |
| 49 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.81799282 |
| 50 | Prostate cancer_Homo sapiens_hsa05215 | 0.80439789 |
| 51 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.80212441 |
| 52 | HTLV-I infection_Homo sapiens_hsa05166 | 0.79974966 |
| 53 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.78772631 |
| 54 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.78667578 |
| 55 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74582950 |
| 56 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.73748255 |
| 57 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.73716949 |
| 58 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.72638784 |
| 59 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71542285 |
| 60 | Influenza A_Homo sapiens_hsa05164 | 0.67635828 |
| 61 | Insulin secretion_Homo sapiens_hsa04911 | 0.66683867 |
| 62 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.65861624 |
| 63 | Insulin resistance_Homo sapiens_hsa04931 | 0.64167883 |
| 64 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.64148981 |
| 65 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.61765108 |
| 66 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.60483149 |
| 67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.59668916 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.55872199 |
| 69 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.52352401 |
| 70 | Pertussis_Homo sapiens_hsa05133 | 0.51984757 |
| 71 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51466930 |
| 72 | Lysosome_Homo sapiens_hsa04142 | 0.50334329 |
| 73 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49929218 |
| 74 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.48937160 |
| 75 | Malaria_Homo sapiens_hsa05144 | 0.48816802 |
| 76 | Tuberculosis_Homo sapiens_hsa05152 | 0.47451247 |
| 77 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.46485672 |
| 78 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.43021721 |
| 79 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.42779292 |
| 80 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.42154958 |
| 81 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.41629902 |
| 82 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.40355944 |
| 83 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.39704968 |
| 84 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.37904999 |
| 85 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.37717834 |
| 86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.37551695 |
| 87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.36629594 |
| 88 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.36276390 |
| 89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.35380280 |
| 90 | Phagosome_Homo sapiens_hsa04145 | 0.33975680 |
| 91 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.32353069 |
| 92 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.26585634 |
| 93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.25526483 |
| 94 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.25375505 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.24679106 |
| 96 | Morphine addiction_Homo sapiens_hsa05032 | 0.22522444 |
| 97 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.22508335 |
| 98 | ABC transporters_Homo sapiens_hsa02010 | 0.20989895 |
| 99 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.19120085 |
| 100 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.18122395 |

