

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | tolerance induction (GO:0002507) | 7.12849074 |
| 2 | negative T cell selection (GO:0043383) | 6.88938466 |
| 3 | negative thymic T cell selection (GO:0045060) | 6.65912741 |
| 4 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.64340635 |
| 5 | negative regulation of cell killing (GO:0031342) | 6.64340635 |
| 6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.54015531 |
| 7 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.45580299 |
| 8 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.38621049 |
| 9 | regulation of regulatory T cell differentiation (GO:0045589) | 6.18907341 |
| 10 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.03523661 |
| 11 | response to interleukin-15 (GO:0070672) | 5.92389675 |
| 12 | cellular response to interleukin-15 (GO:0071350) | 5.84383179 |
| 13 | regulation of T cell tolerance induction (GO:0002664) | 5.53927415 |
| 14 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.50933755 |
| 15 | negative regulation of T cell mediated immunity (GO:0002710) | 5.49918035 |
| 16 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.45564165 |
| 17 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.45519784 |
| 18 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.42984439 |
| 19 | thymic T cell selection (GO:0045061) | 5.28863237 |
| 20 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.16804000 |
| 21 | T cell selection (GO:0045058) | 5.10058802 |
| 22 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.09140633 |
| 23 | positive regulation of tolerance induction (GO:0002645) | 5.01790197 |
| 24 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.89817535 |
| 25 | positive T cell selection (GO:0043368) | 4.83674506 |
| 26 | regulation of gamma-delta T cell activation (GO:0046643) | 4.82015649 |
| 27 | activated T cell proliferation (GO:0050798) | 4.80956065 |
| 28 | leukocyte aggregation (GO:0070486) | 4.68105365 |
| 29 | regulation of tolerance induction (GO:0002643) | 4.68034082 |
| 30 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.61712432 |
| 31 | positive thymic T cell selection (GO:0045059) | 4.59475482 |
| 32 | T cell migration (GO:0072678) | 4.52264428 |
| 33 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.39805335 |
| 34 | positive regulation of granulocyte differentiation (GO:0030854) | 4.28294767 |
| 35 | T cell receptor signaling pathway (GO:0050852) | 4.11738970 |
| 36 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.08567268 |
| 37 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.08567268 |
| 38 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.00185972 |
| 39 | alpha-beta T cell differentiation (GO:0046632) | 3.93000761 |
| 40 | T cell homeostasis (GO:0043029) | 3.92643192 |
| 41 | interferon-gamma production (GO:0032609) | 3.90833355 |
| 42 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.88790448 |
| 43 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.87105016 |
| 44 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.84926937 |
| 45 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.82667201 |
| 46 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.81689548 |
| 47 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.69804405 |
| 48 | positive regulation of interleukin-4 production (GO:0032753) | 3.68779115 |
| 49 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.68359758 |
| 50 | NIK/NF-kappaB signaling (GO:0038061) | 3.67369523 |
| 51 | positive regulation of B cell differentiation (GO:0045579) | 3.66258080 |
| 52 | regulation of B cell differentiation (GO:0045577) | 3.64761697 |
| 53 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.63313828 |
| 54 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.63141547 |
| 55 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.61115134 |
| 56 | alpha-beta T cell activation (GO:0046631) | 3.57748260 |
| 57 | negative regulation of interleukin-12 production (GO:0032695) | 3.47130761 |
| 58 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.45737011 |
| 59 | mast cell activation (GO:0045576) | 3.45607104 |
| 60 | type I interferon signaling pathway (GO:0060337) | 3.44791530 |
| 61 | cellular response to type I interferon (GO:0071357) | 3.44791530 |
| 62 | positive regulation of interleukin-2 production (GO:0032743) | 3.42892295 |
| 63 | response to type I interferon (GO:0034340) | 3.40907627 |
| 64 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.40376614 |
| 65 | positive regulation of cell killing (GO:0031343) | 3.39406674 |
| 66 | regulation of interleukin-4 production (GO:0032673) | 3.37167106 |
| 67 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.35005926 |
| 68 | regulation of isotype switching (GO:0045191) | 3.33835882 |
| 69 | regulation of cell killing (GO:0031341) | 3.33341033 |
| 70 | negative regulation of adaptive immune response (GO:0002820) | 3.30693828 |
| 71 | positive regulation of T cell mediated immunity (GO:0002711) | 3.28597823 |
| 72 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.27852167 |
| 73 | T cell costimulation (GO:0031295) | 3.27342347 |
| 74 | detection of bacterium (GO:0016045) | 3.27179966 |
| 75 | positive regulation of humoral immune response (GO:0002922) | 3.26271993 |
| 76 | negative regulation of B cell mediated immunity (GO:0002713) | 3.24319216 |
| 77 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.24319216 |
| 78 | lymphocyte costimulation (GO:0031294) | 3.23007711 |
| 79 | lymphocyte migration (GO:0072676) | 3.21518979 |
| 80 | T cell differentiation (GO:0030217) | 3.21507606 |
| 81 | B cell receptor signaling pathway (GO:0050853) | 3.20314026 |
| 82 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.19047463 |
| 83 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.19014094 |
| 84 | regulation of interleukin-2 production (GO:0032663) | 3.18375721 |
| 85 | regulation of alpha-beta T cell activation (GO:0046634) | 3.18373504 |
| 86 | T-helper cell differentiation (GO:0042093) | 3.17688756 |
| 87 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.17688756 |
| 88 | regulation of T cell mediated immunity (GO:0002709) | 3.17202247 |
| 89 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.17132867 |
| 90 | detection of other organism (GO:0098543) | 3.17021822 |
| 91 | myeloid dendritic cell differentiation (GO:0043011) | 3.15472252 |
| 92 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.13588865 |
| 93 | positive regulation of isotype switching (GO:0045830) | 3.10666981 |
| 94 | regulation of T cell cytokine production (GO:0002724) | 3.07904579 |
| 95 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.07331983 |
| 96 | regulation of defense response to virus by virus (GO:0050690) | 3.06603953 |
| 97 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.05481015 |
| 98 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 3.03937639 |
| 99 | lymphocyte homeostasis (GO:0002260) | 3.03161290 |
| 100 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.02891443 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.40471474 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.75818979 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.83420266 |
| 4 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.99867861 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.79979329 |
| 6 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.55036485 |
| 7 | MYB_26560356_Chip-Seq_TH2_Human | 3.47485857 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.38046692 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.33037321 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.30346744 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.18367413 |
| 12 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.02675594 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.93366885 |
| 14 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.91575141 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.89919614 |
| 16 | MAF_26560356_Chip-Seq_TH1_Human | 2.85053036 |
| 17 | MYB_26560356_Chip-Seq_TH1_Human | 2.78882766 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.50595118 |
| 19 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.43758750 |
| 20 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.32536322 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.30987292 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.30622340 |
| 23 | MYC_22102868_ChIP-Seq_BL_Human | 2.30453625 |
| 24 | MAF_26560356_Chip-Seq_TH2_Human | 2.30295430 |
| 25 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.20671169 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.19295830 |
| 27 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.12583252 |
| 28 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.11789756 |
| 29 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.98168949 |
| 30 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.96072985 |
| 31 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.90954638 |
| 32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.88254717 |
| 33 | GATA3_26560356_Chip-Seq_TH2_Human | 1.79947072 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.75161817 |
| 35 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.74042001 |
| 36 | SPI1_23127762_ChIP-Seq_K562_Human | 1.73420011 |
| 37 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72746413 |
| 38 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.69020297 |
| 39 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.68302445 |
| 40 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.67150104 |
| 41 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.65266869 |
| 42 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.61912103 |
| 43 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.61185600 |
| 44 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.60285900 |
| 45 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.57395764 |
| 46 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.55656803 |
| 47 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.44202058 |
| 48 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.43967873 |
| 49 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37896570 |
| 50 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.32374588 |
| 51 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.32321015 |
| 52 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.31786259 |
| 53 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.30467487 |
| 54 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29707241 |
| 55 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.29002538 |
| 56 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.26849466 |
| 57 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.24045540 |
| 58 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20359139 |
| 59 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.19547510 |
| 60 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.19414078 |
| 61 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.18808926 |
| 62 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.18719675 |
| 63 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.18382072 |
| 64 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.17979415 |
| 65 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.16060150 |
| 66 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.14514695 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11599771 |
| 68 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.10864106 |
| 69 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.10163352 |
| 70 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.09492107 |
| 71 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.06782530 |
| 72 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.00716940 |
| 73 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.99477902 |
| 74 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.99101144 |
| 75 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.98476345 |
| 76 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.98149597 |
| 77 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.98067673 |
| 78 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96388965 |
| 79 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95962070 |
| 80 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.91844527 |
| 81 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90547401 |
| 82 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89720262 |
| 83 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.89359056 |
| 84 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.87878861 |
| 85 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.86472169 |
| 86 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.85488806 |
| 87 | GATA1_22025678_ChIP-Seq_K562_Human | 0.84797275 |
| 88 | GATA3_26560356_Chip-Seq_TH1_Human | 0.82837724 |
| 89 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82770848 |
| 90 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.81965488 |
| 91 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80778301 |
| 92 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.78310918 |
| 93 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.76118720 |
| 94 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.72716516 |
| 95 | GATA1_19941826_ChIP-Seq_K562_Human | 0.71964998 |
| 96 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.71907367 |
| 97 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.71339010 |
| 98 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70340452 |
| 99 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.65328967 |
| 100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.64982828 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.87693293 |
| 2 | MP0005671_abnormal_response_to | 4.48865790 |
| 3 | MP0003436_decreased_susceptibility_to | 3.65116192 |
| 4 | MP0001873_stomach_inflammation | 3.46433849 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.37457204 |
| 6 | MP0001800_abnormal_humoral_immune | 3.37444923 |
| 7 | MP0009333_abnormal_splenocyte_physiolog | 3.21802906 |
| 8 | MP0005387_immune_system_phenotype | 3.21179333 |
| 9 | MP0001790_abnormal_immune_system | 3.21179333 |
| 10 | MP0003724_increased_susceptibility_to | 3.16470292 |
| 11 | MP0005000_abnormal_immune_tolerance | 3.15572639 |
| 12 | MP0000685_abnormal_immune_system | 2.87635790 |
| 13 | MP0002723_abnormal_immune_serum | 2.78024414 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.73579859 |
| 15 | MP0001819_abnormal_immune_cell | 2.68810126 |
| 16 | MP0003866_abnormal_defecation | 2.58567477 |
| 17 | MP0005025_abnormal_response_to | 2.58202810 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.54516245 |
| 19 | MP0000703_abnormal_thymus_morphology | 2.51799847 |
| 20 | MP0009785_altered_susceptibility_to | 2.50120759 |
| 21 | MP0003303_peritoneal_inflammation | 2.47710438 |
| 22 | MP0002405_respiratory_system_inflammati | 2.45316979 |
| 23 | MP0002398_abnormal_bone_marrow | 2.44392035 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 2.40840532 |
| 25 | MP0003300_gastrointestinal_ulcer | 2.31810121 |
| 26 | MP0004381_abnormal_hair_follicle | 2.25584278 |
| 27 | MP0002419_abnormal_innate_immunity | 2.24079819 |
| 28 | MP0000716_abnormal_immune_system | 2.23358862 |
| 29 | MP0010155_abnormal_intestine_physiology | 2.23146460 |
| 30 | MP0000465_gastrointestinal_hemorrhage | 2.18011103 |
| 31 | MP0006082_CNS_inflammation | 2.08180770 |
| 32 | MP0002277_abnormal_respiratory_mucosa | 2.07528515 |
| 33 | MP0000689_abnormal_spleen_morphology | 2.02131638 |
| 34 | MP0004947_skin_inflammation | 2.00179066 |
| 35 | MP0002722_abnormal_immune_system | 1.98175224 |
| 36 | MP0005310_abnormal_salivary_gland | 1.88510073 |
| 37 | MP0002429_abnormal_blood_cell | 1.75952216 |
| 38 | MP0002166_altered_tumor_susceptibility | 1.74485272 |
| 39 | MP0005464_abnormal_platelet_physiology | 1.70819106 |
| 40 | MP0001845_abnormal_inflammatory_respons | 1.69116616 |
| 41 | MP0001851_eye_inflammation | 1.68940860 |
| 42 | MP0005075_abnormal_melanosome_morpholog | 1.60896085 |
| 43 | MP0008260_abnormal_autophagy | 1.58379086 |
| 44 | MP0001533_abnormal_skeleton_physiology | 1.53407376 |
| 45 | MP0001853_heart_inflammation | 1.45211242 |
| 46 | MP0002396_abnormal_hematopoietic_system | 1.45150060 |
| 47 | MP0002138_abnormal_hepatobiliary_system | 1.40317360 |
| 48 | MP0001348_abnormal_lacrimal_gland | 1.36692472 |
| 49 | MP0000490_abnormal_crypts_of | 1.31541479 |
| 50 | MP0002163_abnormal_gland_morphology | 1.25871869 |
| 51 | MP0002933_joint_inflammation | 1.25835534 |
| 52 | MP0008469_abnormal_protein_level | 1.22732476 |
| 53 | MP0002006_tumorigenesis | 1.15249320 |
| 54 | MP0002132_abnormal_respiratory_system | 1.12737780 |
| 55 | MP0001663_abnormal_digestive_system | 1.10476247 |
| 56 | MP0004510_myositis | 1.06259061 |
| 57 | MP0002009_preneoplasia | 1.05549138 |
| 58 | MP0003045_fibrosis | 0.98925936 |
| 59 | MP0000858_altered_metastatic_potential | 0.97669125 |
| 60 | MP0003172_abnormal_lysosome_physiology | 0.95226576 |
| 61 | MP0009764_decreased_sensitivity_to | 0.82992072 |
| 62 | MP0009763_increased_sensitivity_to | 0.81363406 |
| 63 | MP0003448_altered_tumor_morphology | 0.81124643 |
| 64 | MP0002998_abnormal_bone_remodeling | 0.81116806 |
| 65 | MP0003828_pulmonary_edema | 0.74694598 |
| 66 | MP0002019_abnormal_tumor_incidence | 0.71596191 |
| 67 | MP0002693_abnormal_pancreas_physiology | 0.70461939 |
| 68 | MP0003191_abnormal_cellular_cholesterol | 0.68267083 |
| 69 | MP0005451_abnormal_body_composition | 0.65208690 |
| 70 | MP0009278_abnormal_bone_marrow | 0.63212235 |
| 71 | MP0004883_abnormal_blood_vessel | 0.63196650 |
| 72 | MP0005381_digestive/alimentary_phenotyp | 0.62963362 |
| 73 | MP0000015_abnormal_ear_pigmentation | 0.59438834 |
| 74 | MP0004808_abnormal_hematopoietic_stem | 0.58962584 |
| 75 | MP0008961_abnormal_basal_metabolism | 0.58954729 |
| 76 | MP0002254_reproductive_system_inflammat | 0.58906686 |
| 77 | MP0005166_decreased_susceptibility_to | 0.58238083 |
| 78 | MP0004130_abnormal_muscle_cell | 0.56456755 |
| 79 | MP0005379_endocrine/exocrine_gland_phen | 0.55499211 |
| 80 | MP0000604_amyloidosis | 0.54585507 |
| 81 | MP0009765_abnormal_xenobiotic_induced | 0.53547651 |
| 82 | MP0005390_skeleton_phenotype | 0.51500812 |
| 83 | MP0001919_abnormal_reproductive_system | 0.49195498 |
| 84 | MP0000249_abnormal_blood_vessel | 0.49154543 |
| 85 | MP0008569_lethality_at_weaning | 0.47872637 |
| 86 | MP0003795_abnormal_bone_structure | 0.46041580 |
| 87 | MP0008057_abnormal_DNA_replication | 0.45150491 |
| 88 | MP0000609_abnormal_liver_physiology | 0.43272278 |
| 89 | MP0003091_abnormal_cell_migration | 0.43123065 |
| 90 | MP0008004_abnormal_stomach_pH | 0.39883113 |
| 91 | MP0008874_decreased_physiological_sensi | 0.39613516 |
| 92 | MP0008873_increased_physiological_sensi | 0.37491810 |
| 93 | MP0000372_irregular_coat_pigmentation | 0.35013158 |
| 94 | MP0001765_abnormal_ion_homeostasis | 0.34209665 |
| 95 | MP0003221_abnormal_cardiomyocyte_apopto | 0.34182737 |
| 96 | MP0005164_abnormal_response_to | 0.33741170 |
| 97 | MP0000367_abnormal_coat/_hair | 0.32756954 |
| 98 | MP0000477_abnormal_intestine_morphology | 0.32284268 |
| 99 | MP0003183_abnormal_peptide_metabolism | 0.30698179 |
| 100 | MP0002136_abnormal_kidney_physiology | 0.30660045 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.89775767 |
| 2 | T lymphocytopenia (HP:0005403) | 6.44688360 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.24051228 |
| 4 | Abnormality of T cell number (HP:0011839) | 6.03614735 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 5.70452948 |
| 6 | Eczematoid dermatitis (HP:0000976) | 5.58130895 |
| 7 | Myositis (HP:0100614) | 5.00074689 |
| 8 | Abnormality of T cells (HP:0002843) | 4.83235535 |
| 9 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.44143324 |
| 10 | Severe combined immunodeficiency (HP:0004430) | 4.34834926 |
| 11 | Recurrent abscess formation (HP:0002722) | 4.29933691 |
| 12 | Recurrent bacterial skin infections (HP:0005406) | 4.27819444 |
| 13 | Recurrent fungal infections (HP:0002841) | 4.19060893 |
| 14 | Optic neuritis (HP:0100653) | 4.15690386 |
| 15 | Retrobulbar optic neuritis (HP:0100654) | 4.15690386 |
| 16 | IgG deficiency (HP:0004315) | 4.14281260 |
| 17 | Increased IgM level (HP:0003496) | 4.12372207 |
| 18 | Orchitis (HP:0100796) | 4.06470329 |
| 19 | Abnormality of macrophages (HP:0004311) | 3.96562296 |
| 20 | Mediastinal lymphadenopathy (HP:0100721) | 3.83992965 |
| 21 | Meningitis (HP:0001287) | 3.78500051 |
| 22 | Encephalitis (HP:0002383) | 3.77304726 |
| 23 | Gastrointestinal infarctions (HP:0005244) | 3.74402321 |
| 24 | Pulmonary infiltrates (HP:0002113) | 3.68647672 |
| 25 | Vasculitis (HP:0002633) | 3.59837811 |
| 26 | Chronic obstructive pulmonary disease (HP:0006510) | 3.59643543 |
| 27 | Obstructive lung disease (HP:0006536) | 3.59643543 |
| 28 | Recurrent cutaneous fungal infections (HP:0011370) | 3.56192313 |
| 29 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.56192313 |
| 30 | Abnormality of T cell physiology (HP:0011840) | 3.54794905 |
| 31 | Pustule (HP:0200039) | 3.54553027 |
| 32 | Recurrent bronchitis (HP:0002837) | 3.52036023 |
| 33 | IgM deficiency (HP:0002850) | 3.49651120 |
| 34 | Abnormality of eosinophils (HP:0001879) | 3.43135984 |
| 35 | Panhypogammaglobulinemia (HP:0003139) | 3.41594761 |
| 36 | Chronic diarrhea (HP:0002028) | 3.39553692 |
| 37 | Combined immunodeficiency (HP:0005387) | 3.39315386 |
| 38 | Leukocytosis (HP:0001974) | 3.37585411 |
| 39 | Recurrent viral infections (HP:0004429) | 3.35440166 |
| 40 | Lymphopenia (HP:0001888) | 3.35154320 |
| 41 | Spontaneous hematomas (HP:0007420) | 3.32695478 |
| 42 | Granulocytopenia (HP:0001913) | 3.22765589 |
| 43 | Recurrent skin infections (HP:0001581) | 3.20223496 |
| 44 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.19211743 |
| 45 | Keratoconjunctivitis sicca (HP:0001097) | 3.15873555 |
| 46 | Hypochromic microcytic anemia (HP:0004840) | 3.09241858 |
| 47 | Chest pain (HP:0100749) | 3.06233071 |
| 48 | Eosinophilia (HP:0001880) | 3.02177925 |
| 49 | Joint swelling (HP:0001386) | 2.96128637 |
| 50 | Keratoconjunctivitis (HP:0001096) | 2.92256055 |
| 51 | Hypochromic anemia (HP:0001931) | 2.92096911 |
| 52 | Increased IgE level (HP:0003212) | 2.91696305 |
| 53 | Hemoptysis (HP:0002105) | 2.83377952 |
| 54 | Prolonged bleeding time (HP:0003010) | 2.80990294 |
| 55 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.72251590 |
| 56 | Inflammation of the large intestine (HP:0002037) | 2.71896541 |
| 57 | Gastrointestinal inflammation (HP:0004386) | 2.68835211 |
| 58 | Agammaglobulinemia (HP:0004432) | 2.66423751 |
| 59 | Pulmonary embolism (HP:0002204) | 2.64260160 |
| 60 | Hypergammaglobulinemia (HP:0010702) | 2.63926073 |
| 61 | Epistaxis (HP:0000421) | 2.62901846 |
| 62 | Thyroiditis (HP:0100646) | 2.62250727 |
| 63 | Gingivitis (HP:0000230) | 2.54986600 |
| 64 | Slow saccadic eye movements (HP:0000514) | 2.54140878 |
| 65 | Urticaria (HP:0001025) | 2.50368341 |
| 66 | Verrucae (HP:0200043) | 2.47861033 |
| 67 | Papilloma (HP:0012740) | 2.47861033 |
| 68 | Hypoplasia of the thymus (HP:0000778) | 2.47069930 |
| 69 | Papilledema (HP:0001085) | 2.47044313 |
| 70 | Lymphoma (HP:0002665) | 2.40824325 |
| 71 | Microcytic anemia (HP:0001935) | 2.40486628 |
| 72 | Gangrene (HP:0100758) | 2.40245603 |
| 73 | Acute hepatic failure (HP:0006554) | 2.38883269 |
| 74 | Abnormality of the prostate (HP:0008775) | 2.29072815 |
| 75 | Anorexia (HP:0002039) | 2.24066572 |
| 76 | Petechiae (HP:0000967) | 2.22438885 |
| 77 | Episodic fever (HP:0001954) | 2.19780045 |
| 78 | Gingival bleeding (HP:0000225) | 2.19728412 |
| 79 | Abnormality of the pleura (HP:0002103) | 2.19288843 |
| 80 | Basal cell carcinoma (HP:0002671) | 2.10550667 |
| 81 | Abnormality of B cell number (HP:0010975) | 2.07393528 |
| 82 | Glomerulopathy (HP:0100820) | 2.06417331 |
| 83 | Sepsis (HP:0100806) | 2.06012910 |
| 84 | Arterial thrombosis (HP:0004420) | 2.01127831 |
| 85 | Colitis (HP:0002583) | 1.99907191 |
| 86 | Ileus (HP:0002595) | 1.99556434 |
| 87 | Keratitis (HP:0000491) | 1.96190116 |
| 88 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.95927783 |
| 89 | B lymphocytopenia (HP:0010976) | 1.95620778 |
| 90 | IgA deficiency (HP:0002720) | 1.95193784 |
| 91 | Bronchitis (HP:0012387) | 1.94893452 |
| 92 | Chronic otitis media (HP:0000389) | 1.93411329 |
| 93 | Recurrent sinusitis (HP:0011108) | 1.93112766 |
| 94 | Aplastic anemia (HP:0001915) | 1.92088801 |
| 95 | Cellulitis (HP:0100658) | 1.91463765 |
| 96 | Autoimmune thrombocytopenia (HP:0001973) | 1.90578106 |
| 97 | Skin ulcer (HP:0200042) | 1.90483884 |
| 98 | Nasal polyposis (HP:0100582) | 1.87572966 |
| 99 | Skin rash (HP:0000988) | 1.87508838 |
| 100 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.86038944 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.03463109 |
| 2 | MAP4K1 | 5.07778169 |
| 3 | FES | 3.24758769 |
| 4 | RIPK4 | 2.72875409 |
| 5 | ITK | 2.70639808 |
| 6 | TYK2 | 2.52205324 |
| 7 | CSK | 2.40867911 |
| 8 | ZAP70 | 2.34081289 |
| 9 | NLK | 2.33471578 |
| 10 | SIK3 | 2.26699235 |
| 11 | BTK | 2.25567126 |
| 12 | PASK | 2.13792799 |
| 13 | GRK6 | 2.11238998 |
| 14 | PRPF4B | 2.08998155 |
| 15 | IKBKE | 1.97910730 |
| 16 | LCK | 1.96270404 |
| 17 | JAK3 | 1.94495440 |
| 18 | TEC | 1.78437397 |
| 19 | MAP2K3 | 1.76717584 |
| 20 | JAK1 | 1.74939735 |
| 21 | TAOK3 | 1.72838434 |
| 22 | HCK | 1.68575760 |
| 23 | SYK | 1.64130769 |
| 24 | EPHB1 | 1.62923815 |
| 25 | MAP3K14 | 1.61709348 |
| 26 | IRAK4 | 1.61684359 |
| 27 | CAMKK2 | 1.59816816 |
| 28 | TAOK1 | 1.55693216 |
| 29 | FGFR4 | 1.51757426 |
| 30 | TNK2 | 1.49265287 |
| 31 | MAP3K13 | 1.49127675 |
| 32 | MAP3K11 | 1.44563422 |
| 33 | CAMKK1 | 1.39173998 |
| 34 | BLK | 1.31562588 |
| 35 | MAP3K3 | 1.29463333 |
| 36 | LYN | 1.28081660 |
| 37 | TAOK2 | 1.26245609 |
| 38 | MARK3 | 1.24501324 |
| 39 | MST4 | 1.21810629 |
| 40 | STK10 | 1.14332564 |
| 41 | FGFR3 | 1.14004238 |
| 42 | PRKCQ | 1.13532446 |
| 43 | TBK1 | 1.12730146 |
| 44 | JAK2 | 1.11495693 |
| 45 | IKBKB | 1.07671984 |
| 46 | TYRO3 | 1.04836172 |
| 47 | ERN1 | 0.95748021 |
| 48 | MAP3K1 | 0.94948404 |
| 49 | SIK2 | 0.91157079 |
| 50 | CSF1R | 0.81594255 |
| 51 | LRRK2 | 0.78604680 |
| 52 | PDK1 | 0.75943994 |
| 53 | EPHA3 | 0.72032569 |
| 54 | MAP3K10 | 0.70414625 |
| 55 | FYN | 0.69064087 |
| 56 | PIM1 | 0.68574956 |
| 57 | PIK3CG | 0.67365364 |
| 58 | MAPK11 | 0.66222660 |
| 59 | HIPK2 | 0.64006841 |
| 60 | MAP3K12 | 0.63201659 |
| 61 | MAPK12 | 0.59936797 |
| 62 | YES1 | 0.58989043 |
| 63 | CLK1 | 0.56725756 |
| 64 | FGR | 0.53237571 |
| 65 | MARK2 | 0.51029266 |
| 66 | PDGFRB | 0.47500147 |
| 67 | CDK4 | 0.47171802 |
| 68 | MAP3K5 | 0.45983924 |
| 69 | MAP3K7 | 0.45508216 |
| 70 | PRKCH | 0.45121599 |
| 71 | PTK6 | 0.44943898 |
| 72 | IRAK1 | 0.42236173 |
| 73 | GRK7 | 0.42183487 |
| 74 | KIT | 0.41493949 |
| 75 | MAPKAPK2 | 0.40178155 |
| 76 | CDK19 | 0.39744164 |
| 77 | STK38 | 0.38697107 |
| 78 | TGFBR2 | 0.37933014 |
| 79 | NEK6 | 0.36413961 |
| 80 | TESK2 | 0.34120538 |
| 81 | KSR2 | 0.33715382 |
| 82 | SIK1 | 0.33440902 |
| 83 | SMG1 | 0.31883128 |
| 84 | MAPK7 | 0.30301431 |
| 85 | CHUK | 0.30053510 |
| 86 | PRKD2 | 0.28099406 |
| 87 | KDR | 0.27251877 |
| 88 | MELK | 0.26351275 |
| 89 | MAP2K6 | 0.25856099 |
| 90 | INSR | 0.25095429 |
| 91 | CDK12 | 0.24245349 |
| 92 | IGF1R | 0.22470696 |
| 93 | DYRK1B | 0.21746328 |
| 94 | RET | 0.21740734 |
| 95 | BMPR2 | 0.19564442 |
| 96 | NTRK2 | 0.19518813 |
| 97 | ALK | 0.19417882 |
| 98 | BRD4 | 0.19372142 |
| 99 | EGFR | 0.19000465 |
| 100 | PDPK1 | 0.17218610 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.72319853 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.72869655 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.11055446 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.98865424 |
| 5 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.97260239 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.87760316 |
| 7 | Measles_Homo sapiens_hsa05162 | 2.74501913 |
| 8 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.48663008 |
| 9 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.43123764 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.22636210 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.17340301 |
| 12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.09780637 |
| 13 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.09048217 |
| 14 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.99414503 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.99175018 |
| 16 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.86238476 |
| 17 | Leishmaniasis_Homo sapiens_hsa05140 | 1.81361645 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.78246718 |
| 19 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.76935452 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.74435119 |
| 21 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.63874534 |
| 22 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.62398707 |
| 23 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.60567074 |
| 24 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.55315966 |
| 25 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.54450958 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52789784 |
| 27 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.38015231 |
| 28 | Hepatitis B_Homo sapiens_hsa05161 | 1.36013902 |
| 29 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.32401935 |
| 30 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.29405887 |
| 31 | Malaria_Homo sapiens_hsa05144 | 1.28448918 |
| 32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.27832026 |
| 33 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.27444977 |
| 34 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.27370481 |
| 35 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.26860965 |
| 36 | Tuberculosis_Homo sapiens_hsa05152 | 1.21872355 |
| 37 | Influenza A_Homo sapiens_hsa05164 | 1.18872757 |
| 38 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.16191153 |
| 39 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.12474360 |
| 40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.07959933 |
| 41 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.06516965 |
| 42 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.06466341 |
| 43 | Apoptosis_Homo sapiens_hsa04210 | 1.05011911 |
| 44 | Platelet activation_Homo sapiens_hsa04611 | 1.03558524 |
| 45 | Shigellosis_Homo sapiens_hsa05131 | 1.01160707 |
| 46 | HTLV-I infection_Homo sapiens_hsa05166 | 0.98353300 |
| 47 | Colorectal cancer_Homo sapiens_hsa05210 | 0.98027402 |
| 48 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.95653533 |
| 49 | Hepatitis C_Homo sapiens_hsa05160 | 0.94781941 |
| 50 | Legionellosis_Homo sapiens_hsa05134 | 0.91311863 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.90431667 |
| 52 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.86694353 |
| 53 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.86239134 |
| 54 | Asthma_Homo sapiens_hsa05310 | 0.84812456 |
| 55 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84475322 |
| 56 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.80484143 |
| 57 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.78907936 |
| 58 | Endometrial cancer_Homo sapiens_hsa05213 | 0.76612967 |
| 59 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.75457145 |
| 60 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.74641481 |
| 61 | Thyroid cancer_Homo sapiens_hsa05216 | 0.74495694 |
| 62 | Endocytosis_Homo sapiens_hsa04144 | 0.73988325 |
| 63 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.71156548 |
| 64 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.68697801 |
| 65 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.67754243 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.65561060 |
| 67 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.64875863 |
| 68 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56126994 |
| 69 | Pertussis_Homo sapiens_hsa05133 | 0.53029394 |
| 70 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51638402 |
| 71 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.49202603 |
| 72 | Prostate cancer_Homo sapiens_hsa05215 | 0.48499751 |
| 73 | Salmonella infection_Homo sapiens_hsa05132 | 0.47863698 |
| 74 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47505272 |
| 75 | Phagosome_Homo sapiens_hsa04145 | 0.44932074 |
| 76 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.43182273 |
| 77 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.43064193 |
| 78 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.41570316 |
| 79 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.40119958 |
| 80 | Insulin resistance_Homo sapiens_hsa04931 | 0.38430222 |
| 81 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.38112465 |
| 82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37681939 |
| 83 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.37428398 |
| 84 | Ribosome_Homo sapiens_hsa03010 | 0.35997227 |
| 85 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.33285941 |
| 86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.32448647 |
| 87 | Long-term potentiation_Homo sapiens_hsa04720 | 0.31725103 |
| 88 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.30582316 |
| 89 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.30461065 |
| 90 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.29722419 |
| 91 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.28905111 |
| 92 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.26132595 |
| 93 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.25745676 |
| 94 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.24465014 |
| 95 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.23470201 |
| 96 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.21281961 |
| 97 | Proteasome_Homo sapiens_hsa03050 | 0.20989622 |
| 98 | Circadian rhythm_Homo sapiens_hsa04710 | 0.18877106 |
| 99 | RNA degradation_Homo sapiens_hsa03018 | 0.18758736 |
| 100 | Other glycan degradation_Homo sapiens_hsa00511 | 0.17762445 |

