

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | activated T cell proliferation (GO:0050798) | 7.29015541 |
| 2 | positive regulation of natural killer cell differentiation (GO:0032825) | 6.27405971 |
| 3 | intra-S DNA damage checkpoint (GO:0031573) | 5.95447863 |
| 4 | regulation of activation of Janus kinase activity (GO:0010533) | 5.88378244 |
| 5 | antigen processing and presentation via MHC class Ib (GO:0002475) | 5.82951254 |
| 6 | macrophage differentiation (GO:0030225) | 5.75693410 |
| 7 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 5.67117850 |
| 8 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 5.67117850 |
| 9 | negative regulation of mast cell activation (GO:0033004) | 5.45088190 |
| 10 | regulation of RIG-I signaling pathway (GO:0039535) | 5.36983854 |
| 11 | regulation of transforming growth factor beta2 production (GO:0032909) | 5.34466807 |
| 12 | positive regulation of histone H3-K4 methylation (GO:0051571) | 5.33255533 |
| 13 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.15054609 |
| 14 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 5.07128297 |
| 15 | positive regulation of isotype switching (GO:0045830) | 4.96444802 |
| 16 | negative regulation of phagocytosis (GO:0050765) | 4.95666677 |
| 17 | positive T cell selection (GO:0043368) | 4.89935834 |
| 18 | metallo-sulfur cluster assembly (GO:0031163) | 4.84645953 |
| 19 | iron-sulfur cluster assembly (GO:0016226) | 4.84645953 |
| 20 | positive regulation of lipoprotein lipase activity (GO:0051006) | 4.67176500 |
| 21 | positive regulation of triglyceride lipase activity (GO:0061365) | 4.67176500 |
| 22 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 4.66682208 |
| 23 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 4.65451813 |
| 24 | response to interferon-beta (GO:0035456) | 4.57841771 |
| 25 | protein heterotetramerization (GO:0051290) | 4.47824939 |
| 26 | negative regulation of viral genome replication (GO:0045071) | 4.46483924 |
| 27 | positive regulation of DNA recombination (GO:0045911) | 4.45449581 |
| 28 | quinone biosynthetic process (GO:1901663) | 4.44436692 |
| 29 | negative T cell selection (GO:0043383) | 4.42309955 |
| 30 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 4.41128866 |
| 31 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.40146613 |
| 32 | ubiquinone biosynthetic process (GO:0006744) | 4.35094822 |
| 33 | regulation of natural killer cell differentiation (GO:0032823) | 4.34021090 |
| 34 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 4.30647054 |
| 35 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.27822167 |
| 36 | regulation of chromatin binding (GO:0035561) | 4.22815616 |
| 37 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.16594168 |
| 38 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 4.12723608 |
| 39 | cellular response to interleukin-15 (GO:0071350) | 4.04065955 |
| 40 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 4.03208312 |
| 41 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 3.97003456 |
| 42 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.94798955 |
| 43 | heterotypic cell-cell adhesion (GO:0034113) | 3.93543742 |
| 44 | positive regulation of mRNA catabolic process (GO:0061014) | 3.93315565 |
| 45 | T cell selection (GO:0045058) | 3.83346132 |
| 46 | ubiquinone metabolic process (GO:0006743) | 3.81125108 |
| 47 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.79395751 |
| 48 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 3.76496089 |
| 49 | positive regulation of transforming growth factor beta production (GO:0071636) | 3.69891843 |
| 50 | programmed necrotic cell death (GO:0097300) | 3.63331736 |
| 51 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.63205569 |
| 52 | replicative senescence (GO:0090399) | 3.61009341 |
| 53 | rRNA catabolic process (GO:0016075) | 3.58537907 |
| 54 | negative regulation of stress fiber assembly (GO:0051497) | 3.56330869 |
| 55 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.54784230 |
| 56 | necroptotic process (GO:0070266) | 3.54511694 |
| 57 | ribosome assembly (GO:0042255) | 3.51127235 |
| 58 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.48853440 |
| 59 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.46930237 |
| 60 | positive regulation of immunoglobulin production (GO:0002639) | 3.46899120 |
| 61 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.44415254 |
| 62 | positive regulation of interferon-alpha production (GO:0032727) | 3.44025089 |
| 63 | positive regulation of interferon-beta production (GO:0032728) | 3.42614992 |
| 64 | adipose tissue development (GO:0060612) | 3.42342975 |
| 65 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.42171362 |
| 66 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.38970440 |
| 67 | regulation of cholesterol homeostasis (GO:2000188) | 3.37561844 |
| 68 | regulation of interferon-alpha production (GO:0032647) | 3.37405590 |
| 69 | regulation of mRNA catabolic process (GO:0061013) | 3.34515389 |
| 70 | response to type I interferon (GO:0034340) | 3.33658485 |
| 71 | type I interferon signaling pathway (GO:0060337) | 3.33590176 |
| 72 | cellular response to type I interferon (GO:0071357) | 3.33590176 |
| 73 | T cell costimulation (GO:0031295) | 3.32250485 |
| 74 | necrotic cell death (GO:0070265) | 3.31500756 |
| 75 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.31065188 |
| 76 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.30313221 |
| 77 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.28432136 |
| 78 | lymphocyte costimulation (GO:0031294) | 3.27900984 |
| 79 | positive regulation of histone acetylation (GO:0035066) | 3.26353864 |
| 80 | T cell migration (GO:0072678) | 3.24896367 |
| 81 | positive thymic T cell selection (GO:0045059) | 3.24742371 |
| 82 | neuromuscular process controlling posture (GO:0050884) | 3.21507099 |
| 83 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.20763235 |
| 84 | detection of bacterium (GO:0016045) | 3.19042442 |
| 85 | response to interleukin-15 (GO:0070672) | 3.18095763 |
| 86 | negative regulation of B cell proliferation (GO:0030889) | 3.17761909 |
| 87 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.17505036 |
| 88 | isoprenoid biosynthetic process (GO:0008299) | 3.16656767 |
| 89 | regulation of viral genome replication (GO:0045069) | 3.16220599 |
| 90 | regulation of metalloenzyme activity (GO:0048552) | 3.12348528 |
| 91 | T cell receptor signaling pathway (GO:0050852) | 3.08617859 |
| 92 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.06532148 |
| 93 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.06532148 |
| 94 | regulation of isotype switching (GO:0045191) | 3.04353719 |
| 95 | cellular response to zinc ion (GO:0071294) | 3.03141073 |
| 96 | regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 3.02583590 |
| 97 | protein localization to cell surface (GO:0034394) | 3.00265034 |
| 98 | negative regulation of actin filament bundle assembly (GO:0032232) | 2.99337461 |
| 99 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.98962451 |
| 100 | negative regulation of viral entry into host cell (GO:0046597) | 2.97956294 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.84576037 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.31875746 |
| 3 | GATA1_22025678_ChIP-Seq_K562_Human | 4.87906068 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.32767857 |
| 5 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 4.32139085 |
| 6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.17519421 |
| 7 | MYB_26560356_Chip-Seq_TH2_Human | 2.91510552 |
| 8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.86013271 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.79606695 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.68753850 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.61113288 |
| 12 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.39553010 |
| 13 | MYB_26560356_Chip-Seq_TH1_Human | 2.28770889 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.28493150 |
| 15 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.11940303 |
| 16 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.08274499 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.06343251 |
| 18 | GATA3_26560356_Chip-Seq_TH2_Human | 1.99542199 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92327611 |
| 20 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.77032733 |
| 21 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.74308769 |
| 22 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.73783293 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.72945697 |
| 24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.71426366 |
| 25 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.67099643 |
| 26 | UTX_26944678_Chip-Seq_JUKART_Human | 1.65342924 |
| 27 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.64454090 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.61924068 |
| 29 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.61503364 |
| 30 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.61080172 |
| 31 | MAF_26560356_Chip-Seq_TH2_Human | 1.52420122 |
| 32 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51932980 |
| 33 | AR_20517297_ChIP-Seq_VCAP_Human | 1.51281546 |
| 34 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.44045084 |
| 35 | MAF_26560356_Chip-Seq_TH1_Human | 1.44027596 |
| 36 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.39590394 |
| 37 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.39566185 |
| 38 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.39442809 |
| 39 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.38622355 |
| 40 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.37239353 |
| 41 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.35971227 |
| 42 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.30501425 |
| 43 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.26165522 |
| 44 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20539105 |
| 45 | NCOR_22424771_ChIP-Seq_293T_Human | 1.17574292 |
| 46 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.17539625 |
| 47 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.16403299 |
| 48 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.16323355 |
| 49 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10746074 |
| 50 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.07560119 |
| 51 | SPI1_23127762_ChIP-Seq_K562_Human | 1.07389128 |
| 52 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.06380554 |
| 53 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06097453 |
| 54 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.05756463 |
| 55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05483579 |
| 56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.05314127 |
| 57 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.05049751 |
| 58 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 1.04087641 |
| 59 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.02618508 |
| 60 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.00445753 |
| 61 | ERA_21632823_ChIP-Seq_H3396_Human | 1.00285730 |
| 62 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.99874506 |
| 63 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.99546718 |
| 64 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98412969 |
| 65 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97894161 |
| 66 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.97536673 |
| 67 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.97388944 |
| 68 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.93970085 |
| 69 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.92686543 |
| 70 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91800533 |
| 71 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.89521886 |
| 72 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.87925002 |
| 73 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.86458915 |
| 74 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.85389192 |
| 75 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.84770782 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.84314938 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.84314938 |
| 78 | GATA1_19941826_ChIP-Seq_K562_Human | 0.83410933 |
| 79 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.83017493 |
| 80 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.82087153 |
| 81 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.81949158 |
| 82 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.81573141 |
| 83 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.80079827 |
| 84 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.79102282 |
| 85 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.79046531 |
| 86 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.78971006 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.78273898 |
| 88 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.78183758 |
| 89 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.78147511 |
| 90 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.78035810 |
| 91 | GATA3_26560356_Chip-Seq_TH1_Human | 0.77430193 |
| 92 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.76227049 |
| 93 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.75257814 |
| 94 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.74552116 |
| 95 | VDR_22108803_ChIP-Seq_LS180_Human | 0.74292347 |
| 96 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.74080195 |
| 97 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.73896795 |
| 98 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.73896795 |
| 99 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.73242647 |
| 100 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.72534721 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 6.89847463 |
| 2 | MP0003763_abnormal_thymus_physiology | 5.59468406 |
| 3 | MP0005671_abnormal_response_to | 5.58705810 |
| 4 | MP0002653_abnormal_ependyma_morphology | 4.03775962 |
| 5 | MP0000685_abnormal_immune_system | 3.49445496 |
| 6 | MP0009840_abnormal_foam_cell | 2.99962881 |
| 7 | MP0003191_abnormal_cellular_cholesterol | 2.98715228 |
| 8 | MP0009785_altered_susceptibility_to | 2.96281389 |
| 9 | MP0005387_immune_system_phenotype | 2.88078651 |
| 10 | MP0001790_abnormal_immune_system | 2.88078651 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.85576774 |
| 12 | MP0004147_increased_porphyrin_level | 2.70420388 |
| 13 | MP0009278_abnormal_bone_marrow | 2.67552622 |
| 14 | MP0000858_altered_metastatic_potential | 2.61416588 |
| 15 | MP0003880_abnormal_central_pattern | 2.60855904 |
| 16 | MP0005025_abnormal_response_to | 2.43264689 |
| 17 | MP0005451_abnormal_body_composition | 2.32314797 |
| 18 | MP0001800_abnormal_humoral_immune | 2.22106673 |
| 19 | MP0002723_abnormal_immune_serum | 1.99988680 |
| 20 | MP0002638_abnormal_pupillary_reflex | 1.94617380 |
| 21 | MP0004134_abnormal_chest_morphology | 1.89646033 |
| 22 | MP0004885_abnormal_endolymph | 1.87836642 |
| 23 | MP0002420_abnormal_adaptive_immunity | 1.85016342 |
| 24 | MP0001819_abnormal_immune_cell | 1.80773164 |
| 25 | MP0003436_decreased_susceptibility_to | 1.69171432 |
| 26 | MP0004130_abnormal_muscle_cell | 1.60213843 |
| 27 | MP0005503_abnormal_tendon_morphology | 1.59404031 |
| 28 | MP0001851_eye_inflammation | 1.58003857 |
| 29 | MP0005000_abnormal_immune_tolerance | 1.57587756 |
| 30 | MP0002452_abnormal_antigen_presenting | 1.57236547 |
| 31 | MP0001533_abnormal_skeleton_physiology | 1.56512223 |
| 32 | MP0002398_abnormal_bone_marrow | 1.48908825 |
| 33 | MP0010155_abnormal_intestine_physiology | 1.47833890 |
| 34 | MP0002166_altered_tumor_susceptibility | 1.46778125 |
| 35 | MP0000716_abnormal_immune_system | 1.45814387 |
| 36 | MP0003693_abnormal_embryo_hatching | 1.43853324 |
| 37 | MP0001873_stomach_inflammation | 1.42986894 |
| 38 | MP0002148_abnormal_hypersensitivity_rea | 1.38522130 |
| 39 | MP0009379_abnormal_foot_pigmentation | 1.27890656 |
| 40 | MP0005076_abnormal_cell_differentiation | 1.25213636 |
| 41 | MP0002006_tumorigenesis | 1.23955829 |
| 42 | MP0009333_abnormal_splenocyte_physiolog | 1.22612148 |
| 43 | MP0000703_abnormal_thymus_morphology | 1.21882673 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.20925571 |
| 45 | MP0003866_abnormal_defecation | 1.19764271 |
| 46 | MP0002722_abnormal_immune_system | 1.19174889 |
| 47 | MP0003303_peritoneal_inflammation | 1.18014439 |
| 48 | MP0002419_abnormal_innate_immunity | 1.16734140 |
| 49 | MP0002098_abnormal_vibrissa_morphology | 1.11456442 |
| 50 | MP0009115_abnormal_fat_cell | 1.07898473 |
| 51 | MP0002429_abnormal_blood_cell | 1.05484675 |
| 52 | MP0003329_amyloid_beta_deposits | 1.04216431 |
| 53 | MP0002405_respiratory_system_inflammati | 1.02317240 |
| 54 | MP0000689_abnormal_spleen_morphology | 1.01330888 |
| 55 | MP0008469_abnormal_protein_level | 0.98063240 |
| 56 | MP0002095_abnormal_skin_pigmentation | 0.95990110 |
| 57 | MP0010386_abnormal_urinary_bladder | 0.85283520 |
| 58 | MP0002693_abnormal_pancreas_physiology | 0.84818600 |
| 59 | MP0005408_hypopigmentation | 0.79659423 |
| 60 | MP0001963_abnormal_hearing_physiology | 0.73647460 |
| 61 | MP0008961_abnormal_basal_metabolism | 0.72901059 |
| 62 | MP0003638_abnormal_response/metabolism_ | 0.72887250 |
| 63 | MP0009763_increased_sensitivity_to | 0.72229194 |
| 64 | MP0000604_amyloidosis | 0.71038132 |
| 65 | MP0002138_abnormal_hepatobiliary_system | 0.69037054 |
| 66 | MP0008569_lethality_at_weaning | 0.68220355 |
| 67 | MP0005390_skeleton_phenotype | 0.64633686 |
| 68 | MP0001663_abnormal_digestive_system | 0.64109274 |
| 69 | MP0009643_abnormal_urine_homeostasis | 0.60843622 |
| 70 | MP0002168_other_aberrant_phenotype | 0.60492002 |
| 71 | MP0002019_abnormal_tumor_incidence | 0.60391596 |
| 72 | MP0005397_hematopoietic_system_phenotyp | 0.59702903 |
| 73 | MP0001545_abnormal_hematopoietic_system | 0.59702903 |
| 74 | MP0001270_distended_abdomen | 0.59156364 |
| 75 | MP0008058_abnormal_DNA_repair | 0.56951229 |
| 76 | MP0003646_muscle_fatigue | 0.56918971 |
| 77 | MP0005319_abnormal_enzyme/_coenzyme | 0.55453008 |
| 78 | MP0002933_joint_inflammation | 0.55051392 |
| 79 | MP0005266_abnormal_metabolism | 0.54338643 |
| 80 | MP0001853_heart_inflammation | 0.53673875 |
| 81 | MP0001119_abnormal_female_reproductive | 0.53294107 |
| 82 | MP0005410_abnormal_fertilization | 0.51295183 |
| 83 | MP0001666_abnormal_nutrient_absorption | 0.50036016 |
| 84 | MP0001919_abnormal_reproductive_system | 0.49220222 |
| 85 | MP0001765_abnormal_ion_homeostasis | 0.48723629 |
| 86 | MP0001243_abnormal_dermal_layer | 0.48157867 |
| 87 | MP0002078_abnormal_glucose_homeostasis | 0.47805089 |
| 88 | MP0000749_muscle_degeneration | 0.47252235 |
| 89 | MP0000427_abnormal_hair_cycle | 0.46029083 |
| 90 | MP0009764_decreased_sensitivity_to | 0.45997771 |
| 91 | MP0001905_abnormal_dopamine_level | 0.43831401 |
| 92 | MP0005645_abnormal_hypothalamus_physiol | 0.43757333 |
| 93 | MP0002127_abnormal_cardiovascular_syste | 0.43230409 |
| 94 | MP0004381_abnormal_hair_follicle | 0.42344920 |
| 95 | MP0000026_abnormal_inner_ear | 0.41805639 |
| 96 | MP0003172_abnormal_lysosome_physiology | 0.39912968 |
| 97 | MP0004947_skin_inflammation | 0.39138324 |
| 98 | MP0001727_abnormal_embryo_implantation | 0.38681786 |
| 99 | MP0004142_abnormal_muscle_tone | 0.38303910 |
| 100 | MP0002136_abnormal_kidney_physiology | 0.37911490 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Decreased circulating renin level (HP:0003351) | 4.70260892 |
| 2 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 4.40578742 |
| 3 | Abnormality of T cell number (HP:0011839) | 4.26075104 |
| 4 | T lymphocytopenia (HP:0005403) | 4.25540083 |
| 5 | Hypoproteinemia (HP:0003075) | 4.10617814 |
| 6 | Aortic regurgitation (HP:0001659) | 4.10614416 |
| 7 | Stomatitis (HP:0010280) | 3.99943103 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 3.89225693 |
| 9 | Optic neuritis (HP:0100653) | 3.89225693 |
| 10 | IgG deficiency (HP:0004315) | 3.75301343 |
| 11 | Hyperactive renin-angiotensin system (HP:0000841) | 3.63878766 |
| 12 | Orchitis (HP:0100796) | 3.58456183 |
| 13 | Dyschromatopsia (HP:0007641) | 3.58282744 |
| 14 | Myositis (HP:0100614) | 3.43004382 |
| 15 | Hypokalemic alkalosis (HP:0001949) | 3.41923149 |
| 16 | Fatigable weakness (HP:0003473) | 3.33239366 |
| 17 | Abnormality of the neuromuscular junction (HP:0003398) | 3.33239366 |
| 18 | Depressed nasal tip (HP:0000437) | 3.30978166 |
| 19 | Metaphyseal dysplasia (HP:0100255) | 3.30818012 |
| 20 | Increased IgM level (HP:0003496) | 3.20693753 |
| 21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.19744994 |
| 22 | Hyponatremia (HP:0002902) | 3.19151494 |
| 23 | Anorexia (HP:0002039) | 3.16370250 |
| 24 | Hyperaldosteronism (HP:0000859) | 3.13615975 |
| 25 | Severe combined immunodeficiency (HP:0004430) | 3.03986144 |
| 26 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.01223041 |
| 27 | Progressive inability to walk (HP:0002505) | 2.86440290 |
| 28 | Severe muscular hypotonia (HP:0006829) | 2.84581536 |
| 29 | Recurrent cutaneous fungal infections (HP:0011370) | 2.79787817 |
| 30 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.79787817 |
| 31 | Birth length less than 3rd percentile (HP:0003561) | 2.73585249 |
| 32 | Easy fatigability (HP:0003388) | 2.72472861 |
| 33 | Autoimmune hemolytic anemia (HP:0001890) | 2.70517110 |
| 34 | Agammaglobulinemia (HP:0004432) | 2.67163630 |
| 35 | Recurrent bronchitis (HP:0002837) | 2.64512608 |
| 36 | Mitral regurgitation (HP:0001653) | 2.62750577 |
| 37 | Neonatal respiratory distress (HP:0002643) | 2.59676862 |
| 38 | Abnormality of renin-angiotensin system (HP:0000847) | 2.58514249 |
| 39 | Cerebellar dysplasia (HP:0007033) | 2.56499856 |
| 40 | Bronchitis (HP:0012387) | 2.56421545 |
| 41 | Ileus (HP:0002595) | 2.53757739 |
| 42 | Enlarged epiphyses (HP:0010580) | 2.52197346 |
| 43 | Thyroiditis (HP:0100646) | 2.51947025 |
| 44 | Abnormality of sodium homeostasis (HP:0010931) | 2.49434395 |
| 45 | Abnormality of T cells (HP:0002843) | 2.49351374 |
| 46 | Chronic diarrhea (HP:0002028) | 2.49201695 |
| 47 | Inability to walk (HP:0002540) | 2.48586021 |
| 48 | Pustule (HP:0200039) | 2.48441229 |
| 49 | Keratoconjunctivitis sicca (HP:0001097) | 2.48176774 |
| 50 | Anterior segment dysgenesis (HP:0007700) | 2.44944108 |
| 51 | Abnormality of eosinophils (HP:0001879) | 2.44668324 |
| 52 | Chronic bronchitis (HP:0004469) | 2.44652727 |
| 53 | Polyneuropathy (HP:0001271) | 2.43419027 |
| 54 | Renal salt wasting (HP:0000127) | 2.41322383 |
| 55 | Type II lissencephaly (HP:0007260) | 2.40877221 |
| 56 | Hypochromic anemia (HP:0001931) | 2.39530414 |
| 57 | Vacuolated lymphocytes (HP:0001922) | 2.33519123 |
| 58 | Proximal amyotrophy (HP:0007126) | 2.29918485 |
| 59 | 3-Methylglutaconic aciduria (HP:0003535) | 2.27825975 |
| 60 | True hermaphroditism (HP:0010459) | 2.26360768 |
| 61 | Keratoconjunctivitis (HP:0001096) | 2.26347383 |
| 62 | Vasculitis (HP:0002633) | 2.25930126 |
| 63 | Combined immunodeficiency (HP:0005387) | 2.24292389 |
| 64 | Hypoplasia of the thymus (HP:0000778) | 2.23992462 |
| 65 | Cerebral hypomyelination (HP:0006808) | 2.23473929 |
| 66 | Limb hypertonia (HP:0002509) | 2.22572959 |
| 67 | Unsteady gait (HP:0002317) | 2.21385548 |
| 68 | Recurrent fungal infections (HP:0002841) | 2.19189636 |
| 69 | Pancreatic cysts (HP:0001737) | 2.16271339 |
| 70 | Pulmonary infiltrates (HP:0002113) | 2.16157518 |
| 71 | Abnormality of the umbilical cord (HP:0010881) | 2.15749955 |
| 72 | Hypoalbuminemia (HP:0003073) | 2.14361562 |
| 73 | Abnormal albumin level (HP:0012116) | 2.14361562 |
| 74 | Fair hair (HP:0002286) | 2.11702561 |
| 75 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.09072456 |
| 76 | Joint swelling (HP:0001386) | 2.08834783 |
| 77 | Cutis marmorata (HP:0000965) | 2.07446899 |
| 78 | Alkalosis (HP:0001948) | 2.07360504 |
| 79 | Rectal prolapse (HP:0002035) | 2.06467056 |
| 80 | Abnormality of the pleura (HP:0002103) | 2.05697558 |
| 81 | Lymphopenia (HP:0001888) | 2.05605477 |
| 82 | Increased hepatocellular lipid droplets (HP:0006565) | 2.04345759 |
| 83 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.03608003 |
| 84 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.01966966 |
| 85 | Hypoplasia of the fovea (HP:0007750) | 2.01966966 |
| 86 | Pancreatic fibrosis (HP:0100732) | 1.99172228 |
| 87 | Constricted visual fields (HP:0001133) | 1.99132564 |
| 88 | Exotropia (HP:0000577) | 1.99072736 |
| 89 | Bulbar palsy (HP:0001283) | 1.95745489 |
| 90 | Episodic fever (HP:0001954) | 1.94301126 |
| 91 | Abnormality of the nasal septum (HP:0000419) | 1.90741262 |
| 92 | Increased serum lactate (HP:0002151) | 1.90278102 |
| 93 | Diaphragmatic weakness (HP:0009113) | 1.89348991 |
| 94 | Decreased subcutaneous fat (HP:0001002) | 1.87975609 |
| 95 | Leukocytosis (HP:0001974) | 1.87727270 |
| 96 | Hemoptysis (HP:0002105) | 1.84404349 |
| 97 | 11 pairs of ribs (HP:0000878) | 1.83938126 |
| 98 | Focal motor seizures (HP:0011153) | 1.82640235 |
| 99 | Cellular immunodeficiency (HP:0005374) | 1.82267167 |
| 100 | Macular degeneration (HP:0000608) | 1.78278474 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MUSK | 8.34040115 |
| 2 | RIPK1 | 5.64431905 |
| 3 | VRK1 | 4.74430536 |
| 4 | TXK | 4.26403061 |
| 5 | CDK8 | 2.90095913 |
| 6 | BTK | 2.66870079 |
| 7 | TGFBR2 | 2.61791839 |
| 8 | FES | 2.59826583 |
| 9 | VRK2 | 2.43272997 |
| 10 | PRPF4B | 2.31467847 |
| 11 | TYRO3 | 2.25147964 |
| 12 | MAP4K1 | 2.20198764 |
| 13 | CSK | 1.95464848 |
| 14 | KDR | 1.81217645 |
| 15 | IRAK3 | 1.70020447 |
| 16 | HCK | 1.68160860 |
| 17 | TAOK3 | 1.66575219 |
| 18 | PIK3CA | 1.63357045 |
| 19 | TLK1 | 1.47155193 |
| 20 | ZAK | 1.40712564 |
| 21 | NLK | 1.39924491 |
| 22 | SYK | 1.34077740 |
| 23 | JAK3 | 1.33698815 |
| 24 | TRPM7 | 1.25973545 |
| 25 | ADRBK2 | 1.16128644 |
| 26 | MAP2K6 | 1.15118806 |
| 27 | ITK | 1.13177234 |
| 28 | IKBKE | 1.08568228 |
| 29 | TNIK | 1.02892327 |
| 30 | JAK1 | 1.01455146 |
| 31 | LCK | 1.00626720 |
| 32 | TYK2 | 0.92475874 |
| 33 | PLK3 | 0.90384728 |
| 34 | TBK1 | 0.90291350 |
| 35 | PDGFRB | 0.89522231 |
| 36 | TEC | 0.89377129 |
| 37 | MAPK7 | 0.88760464 |
| 38 | SIK3 | 0.85512541 |
| 39 | PKN2 | 0.84374084 |
| 40 | PRKD3 | 0.81824690 |
| 41 | PIK3CG | 0.80177127 |
| 42 | LYN | 0.78933137 |
| 43 | TRIM28 | 0.78598387 |
| 44 | PIM1 | 0.76447965 |
| 45 | ZAP70 | 0.76044230 |
| 46 | KIT | 0.75358265 |
| 47 | FGFR4 | 0.72183106 |
| 48 | FGFR3 | 0.67011583 |
| 49 | MAPKAPK2 | 0.64201391 |
| 50 | PDK1 | 0.59122988 |
| 51 | BUB1 | 0.58637086 |
| 52 | GRK1 | 0.54213465 |
| 53 | PDK2 | 0.52375988 |
| 54 | CLK1 | 0.52124696 |
| 55 | GRK7 | 0.51913434 |
| 56 | PTK2B | 0.49482336 |
| 57 | PRKCE | 0.47947754 |
| 58 | TESK2 | 0.46311766 |
| 59 | IGF1R | 0.44976227 |
| 60 | CDK19 | 0.40984249 |
| 61 | FRK | 0.39118042 |
| 62 | BCKDK | 0.39001136 |
| 63 | MAPK13 | 0.37631942 |
| 64 | JAK2 | 0.36715645 |
| 65 | STK10 | 0.36233110 |
| 66 | RPS6KA5 | 0.35324977 |
| 67 | ADRBK1 | 0.34317524 |
| 68 | LRRK2 | 0.34312032 |
| 69 | PRKCQ | 0.34198386 |
| 70 | FYN | 0.31820977 |
| 71 | IRAK1 | 0.31209820 |
| 72 | IKBKB | 0.29552067 |
| 73 | CHEK2 | 0.28519597 |
| 74 | PRKCH | 0.28377053 |
| 75 | PHKG1 | 0.28278649 |
| 76 | PHKG2 | 0.28278649 |
| 77 | PASK | 0.27297347 |
| 78 | MAPK11 | 0.27295332 |
| 79 | GRK6 | 0.26067158 |
| 80 | TNK2 | 0.24434903 |
| 81 | MAPK9 | 0.24025220 |
| 82 | MAPKAPK3 | 0.22567838 |
| 83 | CDK3 | 0.21822199 |
| 84 | PDPK1 | 0.21292584 |
| 85 | HIPK2 | 0.20948428 |
| 86 | INSRR | 0.20599538 |
| 87 | PRKCB | 0.18938349 |
| 88 | PRKACG | 0.17994067 |
| 89 | PRKACA | 0.17272176 |
| 90 | PRKCG | 0.16505950 |
| 91 | MAPK12 | 0.14383574 |
| 92 | ACVR1B | 0.14286361 |
| 93 | NEK2 | 0.14218820 |
| 94 | DYRK1A | 0.14163030 |
| 95 | RET | 0.13972850 |
| 96 | PRKCA | 0.13750726 |
| 97 | MYLK | 0.12759746 |
| 98 | RPS6KB1 | 0.12401925 |
| 99 | INSR | 0.11857277 |
| 100 | CDK4 | 0.11244238 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.43821339 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.20064079 |
| 3 | Basal transcription factors_Homo sapiens_hsa03022 | 3.03006777 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.87516093 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.86648149 |
| 6 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.43876877 |
| 7 | Malaria_Homo sapiens_hsa05144 | 2.42060227 |
| 8 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.36297770 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.33634459 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.19250748 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.16082364 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.06462891 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.01900195 |
| 14 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.95262008 |
| 15 | Measles_Homo sapiens_hsa05162 | 1.91613140 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.73107055 |
| 17 | Proteasome_Homo sapiens_hsa03050 | 1.64514826 |
| 18 | Ribosome_Homo sapiens_hsa03010 | 1.58559336 |
| 19 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.58497534 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.57779723 |
| 21 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.56960671 |
| 22 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.54812541 |
| 23 | Hepatitis B_Homo sapiens_hsa05161 | 1.53438146 |
| 24 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.46444560 |
| 25 | HTLV-I infection_Homo sapiens_hsa05166 | 1.39972085 |
| 26 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.39576103 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.39425582 |
| 28 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.28334764 |
| 29 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.26361448 |
| 30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.21801695 |
| 31 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.19317431 |
| 32 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.17000318 |
| 33 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.16118578 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.15985007 |
| 35 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.13470529 |
| 36 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.12136996 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.08848075 |
| 38 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.06068604 |
| 39 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.03280528 |
| 40 | Allograft rejection_Homo sapiens_hsa05330 | 0.99419475 |
| 41 | Influenza A_Homo sapiens_hsa05164 | 0.89593448 |
| 42 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.87050426 |
| 43 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85645973 |
| 44 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.84896741 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.84313897 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.81346497 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.81217496 |
| 48 | Cocaine addiction_Homo sapiens_hsa05030 | 0.80987741 |
| 49 | Platelet activation_Homo sapiens_hsa04611 | 0.80884020 |
| 50 | Viral myocarditis_Homo sapiens_hsa05416 | 0.80140963 |
| 51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.78176313 |
| 52 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.77999595 |
| 53 | Shigellosis_Homo sapiens_hsa05131 | 0.75525433 |
| 54 | Insulin resistance_Homo sapiens_hsa04931 | 0.75393928 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.74627019 |
| 56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.74053992 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.73460669 |
| 58 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.73244239 |
| 59 | RNA degradation_Homo sapiens_hsa03018 | 0.69847909 |
| 60 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.66495523 |
| 61 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66379394 |
| 62 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64723351 |
| 63 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.62846524 |
| 64 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.60442040 |
| 65 | ABC transporters_Homo sapiens_hsa02010 | 0.59724582 |
| 66 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.59219948 |
| 67 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.56185867 |
| 68 | Parkinsons disease_Homo sapiens_hsa05012 | 0.56004698 |
| 69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.55408120 |
| 70 | Leishmaniasis_Homo sapiens_hsa05140 | 0.54904275 |
| 71 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.54736178 |
| 72 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.52248017 |
| 73 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.51212264 |
| 74 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.48155306 |
| 75 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.46576368 |
| 76 | Tuberculosis_Homo sapiens_hsa05152 | 0.45745265 |
| 77 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.45514457 |
| 78 | Hepatitis C_Homo sapiens_hsa05160 | 0.45282044 |
| 79 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.44242515 |
| 80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42655377 |
| 81 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.42325536 |
| 82 | Sulfur relay system_Homo sapiens_hsa04122 | 0.42180723 |
| 83 | Huntingtons disease_Homo sapiens_hsa05016 | 0.41015690 |
| 84 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.40318027 |
| 85 | Colorectal cancer_Homo sapiens_hsa05210 | 0.39628644 |
| 86 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.38394066 |
| 87 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.38118374 |
| 88 | Pertussis_Homo sapiens_hsa05133 | 0.37718631 |
| 89 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.36290524 |
| 90 | Phototransduction_Homo sapiens_hsa04744 | 0.36063742 |
| 91 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.35306895 |
| 92 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.31602258 |
| 93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.31515539 |
| 94 | Asthma_Homo sapiens_hsa05310 | 0.30571185 |
| 95 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.30460544 |
| 96 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.29298976 |
| 97 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.27818548 |
| 98 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.27448974 |
| 99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.27428005 |
| 100 | Olfactory transduction_Homo sapiens_hsa04740 | 0.25734048 |

