

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to interleukin-15 (GO:0070672) | 7.64377569 |
| 2 | cellular response to interleukin-15 (GO:0071350) | 7.35969045 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 7.27450614 |
| 4 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 7.10855251 |
| 5 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.83109314 |
| 6 | tolerance induction (GO:0002507) | 6.73913961 |
| 7 | regulation of gamma-delta T cell differentiation (GO:0045586) | 6.72675736 |
| 8 | interferon-gamma production (GO:0032609) | 6.63589325 |
| 9 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.61670405 |
| 10 | negative T cell selection (GO:0043383) | 6.10817817 |
| 11 | regulation of gamma-delta T cell activation (GO:0046643) | 5.89895265 |
| 12 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.76676306 |
| 13 | negative thymic T cell selection (GO:0045060) | 5.72912822 |
| 14 | positive regulation of natural killer cell differentiation (GO:0032825) | 5.46009747 |
| 15 | regulation of regulatory T cell differentiation (GO:0045589) | 5.42280054 |
| 16 | alpha-beta T cell differentiation (GO:0046632) | 5.41173689 |
| 17 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.34906623 |
| 18 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.24650520 |
| 19 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 5.11714441 |
| 20 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.10301453 |
| 21 | negative regulation of cell killing (GO:0031342) | 5.05440815 |
| 22 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.05440815 |
| 23 | activated T cell proliferation (GO:0050798) | 4.84276942 |
| 24 | alpha-beta T cell activation (GO:0046631) | 4.83847045 |
| 25 | T cell migration (GO:0072678) | 4.82934408 |
| 26 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.75447075 |
| 27 | thymic T cell selection (GO:0045061) | 4.74773369 |
| 28 | T cell selection (GO:0045058) | 4.69863600 |
| 29 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.62515676 |
| 30 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.62515676 |
| 31 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.56911429 |
| 32 | leukocyte aggregation (GO:0070486) | 4.56659686 |
| 33 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.46893775 |
| 34 | positive T cell selection (GO:0043368) | 4.42556523 |
| 35 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.35530830 |
| 36 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.32224754 |
| 37 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.25562205 |
| 38 | T cell homeostasis (GO:0043029) | 4.25402997 |
| 39 | regulation of T cell tolerance induction (GO:0002664) | 4.22457770 |
| 40 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.21941243 |
| 41 | T cell differentiation (GO:0030217) | 4.04723727 |
| 42 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 4.03226129 |
| 43 | regulation of interleukin-2 production (GO:0032663) | 3.99580169 |
| 44 | T cell receptor signaling pathway (GO:0050852) | 3.98062604 |
| 45 | positive thymic T cell selection (GO:0045059) | 3.95899354 |
| 46 | mast cell activation (GO:0045576) | 3.90671575 |
| 47 | positive regulation of B cell differentiation (GO:0045579) | 3.90610541 |
| 48 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.89270112 |
| 49 | positive regulation of interleukin-2 production (GO:0032743) | 3.87591545 |
| 50 | mast cell activation involved in immune response (GO:0002279) | 3.85577725 |
| 51 | mast cell degranulation (GO:0043303) | 3.85577725 |
| 52 | positive regulation of tolerance induction (GO:0002645) | 3.85493106 |
| 53 | cytokine biosynthetic process (GO:0042089) | 3.85006752 |
| 54 | regulation of natural killer cell differentiation (GO:0032823) | 3.81699214 |
| 55 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.73562818 |
| 56 | regulation of B cell differentiation (GO:0045577) | 3.71589490 |
| 57 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 3.65914325 |
| 58 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.64635029 |
| 59 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.62920645 |
| 60 | positive regulation of cell killing (GO:0031343) | 3.54352808 |
| 61 | regulation of tolerance induction (GO:0002643) | 3.52772774 |
| 62 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.52745592 |
| 63 | Peyers patch development (GO:0048541) | 3.47479931 |
| 64 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.47479931 |
| 65 | T cell proliferation (GO:0042098) | 3.46895378 |
| 66 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.46512395 |
| 67 | regulation of defense response to virus by virus (GO:0050690) | 3.45796280 |
| 68 | T cell activation (GO:0042110) | 3.42849492 |
| 69 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.39948651 |
| 70 | T cell costimulation (GO:0031295) | 3.39776306 |
| 71 | negative regulation of T cell mediated immunity (GO:0002710) | 3.37292416 |
| 72 | T cell mediated immunity (GO:0002456) | 3.35542288 |
| 73 | positive regulation of humoral immune response (GO:0002922) | 3.35449041 |
| 74 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.35230348 |
| 75 | lymphocyte costimulation (GO:0031294) | 3.35121224 |
| 76 | regulation of cell killing (GO:0031341) | 3.33986929 |
| 77 | chemokine-mediated signaling pathway (GO:0070098) | 3.30556244 |
| 78 | T-helper cell differentiation (GO:0042093) | 3.30364325 |
| 79 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.30364325 |
| 80 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.30335644 |
| 81 | mature B cell differentiation (GO:0002335) | 3.28748901 |
| 82 | myeloid dendritic cell differentiation (GO:0043011) | 3.28054407 |
| 83 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.27981087 |
| 84 | positive regulation of granulocyte differentiation (GO:0030854) | 3.24028398 |
| 85 | cytokine metabolic process (GO:0042107) | 3.23504596 |
| 86 | myeloid dendritic cell activation (GO:0001773) | 3.18649964 |
| 87 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.16011274 |
| 88 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.15209036 |
| 89 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.12831403 |
| 90 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.12831403 |
| 91 | T cell differentiation involved in immune response (GO:0002292) | 3.12831403 |
| 92 | dendritic cell chemotaxis (GO:0002407) | 3.09618149 |
| 93 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.05991566 |
| 94 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.05207173 |
| 95 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.02468458 |
| 96 | lymphocyte differentiation (GO:0030098) | 3.01598990 |
| 97 | regulation of response to interferon-gamma (GO:0060330) | 3.01405680 |
| 98 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.01320740 |
| 99 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.00442136 |
| 100 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.00404633 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 8.81969354 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 7.99407773 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.29948934 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.41641486 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.88138136 |
| 6 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.64176695 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.33285875 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.32052683 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.05993900 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.99747837 |
| 11 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.75981442 |
| 12 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.52317289 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.47756125 |
| 14 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.40540049 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.35834174 |
| 16 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.32161496 |
| 17 | MYB_26560356_Chip-Seq_TH1_Human | 2.30649176 |
| 18 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.18841778 |
| 19 | MAF_26560356_Chip-Seq_TH1_Human | 2.07639099 |
| 20 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.01384116 |
| 21 | UTX_26944678_Chip-Seq_JUKART_Human | 1.93283095 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.90023122 |
| 23 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.86232165 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.82080240 |
| 25 | MAF_26560356_Chip-Seq_TH2_Human | 1.81762862 |
| 26 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.79627713 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.76853723 |
| 28 | GATA3_26560356_Chip-Seq_TH2_Human | 1.75691549 |
| 29 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.70558274 |
| 30 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.68732077 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.64031587 |
| 32 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.61603475 |
| 33 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59970861 |
| 34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.55850907 |
| 35 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.52752673 |
| 36 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.44374370 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.43318749 |
| 38 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42199160 |
| 39 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.38330726 |
| 40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34399512 |
| 41 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.31083869 |
| 42 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.29465409 |
| 43 | MYC_22102868_ChIP-Seq_BL_Human | 1.28947034 |
| 44 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.26860399 |
| 45 | SPI1_23127762_ChIP-Seq_K562_Human | 1.23815451 |
| 46 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.20914065 |
| 47 | VDR_22108803_ChIP-Seq_LS180_Human | 1.20898969 |
| 48 | GATA1_22025678_ChIP-Seq_K562_Human | 1.20258130 |
| 49 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.17629351 |
| 50 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.16615419 |
| 51 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14560734 |
| 52 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.12786236 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.11038637 |
| 54 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.10074967 |
| 55 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07661519 |
| 56 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.03993786 |
| 57 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97816343 |
| 58 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.96657748 |
| 59 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.95953127 |
| 60 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.93744232 |
| 61 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92316301 |
| 62 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90422172 |
| 63 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.89877728 |
| 64 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89574389 |
| 65 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.89008116 |
| 66 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.88857084 |
| 67 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.88076897 |
| 68 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.86834098 |
| 69 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.85784377 |
| 70 | GATA3_26560356_Chip-Seq_TH1_Human | 0.82508401 |
| 71 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82446684 |
| 72 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.82403805 |
| 73 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.82368340 |
| 74 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82250842 |
| 75 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.81741718 |
| 76 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.81671226 |
| 77 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.80064126 |
| 78 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.79011752 |
| 79 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.78471062 |
| 80 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.78028955 |
| 81 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.77693779 |
| 82 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.75963221 |
| 83 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.72920834 |
| 84 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.71940248 |
| 85 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.70496642 |
| 86 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.69052955 |
| 87 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.68661605 |
| 88 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.68306811 |
| 89 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.67190971 |
| 90 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.66943799 |
| 91 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.66629606 |
| 92 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.65769101 |
| 93 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.65756285 |
| 94 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.65738103 |
| 95 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.65688239 |
| 96 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.65423202 |
| 97 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.62987142 |
| 98 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.62718157 |
| 99 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.62716260 |
| 100 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.60730332 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.00477028 |
| 2 | MP0001873_stomach_inflammation | 4.41395594 |
| 3 | MP0003763_abnormal_thymus_physiology | 4.35081520 |
| 4 | MP0005387_immune_system_phenotype | 4.00059421 |
| 5 | MP0001790_abnormal_immune_system | 4.00059421 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.74774973 |
| 7 | MP0001800_abnormal_humoral_immune | 3.51718749 |
| 8 | MP0003866_abnormal_defecation | 3.38335948 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.94133985 |
| 10 | MP0002723_abnormal_immune_serum | 2.90074985 |
| 11 | MP0009785_altered_susceptibility_to | 2.81199101 |
| 12 | MP0009333_abnormal_splenocyte_physiolog | 2.80129936 |
| 13 | MP0000465_gastrointestinal_hemorrhage | 2.77510906 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.68690507 |
| 15 | MP0001819_abnormal_immune_cell | 2.63836633 |
| 16 | MP0000685_abnormal_immune_system | 2.59525366 |
| 17 | MP0005025_abnormal_response_to | 2.57788978 |
| 18 | MP0010155_abnormal_intestine_physiology | 2.56835833 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.55600823 |
| 20 | MP0003436_decreased_susceptibility_to | 2.45192539 |
| 21 | MP0002405_respiratory_system_inflammati | 2.37843251 |
| 22 | MP0009384_cardiac_valve_regurgitation | 2.35496458 |
| 23 | MP0002398_abnormal_bone_marrow | 2.29146902 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 2.27618952 |
| 25 | MP0000703_abnormal_thymus_morphology | 2.26158117 |
| 26 | MP0002166_altered_tumor_susceptibility | 2.20754564 |
| 27 | MP0000716_abnormal_immune_system | 2.06228936 |
| 28 | MP0003724_increased_susceptibility_to | 2.02373122 |
| 29 | MP0000689_abnormal_spleen_morphology | 1.98964738 |
| 30 | MP0001845_abnormal_inflammatory_respons | 1.94701237 |
| 31 | MP0006082_CNS_inflammation | 1.87052641 |
| 32 | MP0002722_abnormal_immune_system | 1.86969204 |
| 33 | MP0002419_abnormal_innate_immunity | 1.86184005 |
| 34 | MP0001348_abnormal_lacrimal_gland | 1.77313997 |
| 35 | MP0004381_abnormal_hair_follicle | 1.70663602 |
| 36 | MP0002933_joint_inflammation | 1.69389914 |
| 37 | MP0002429_abnormal_blood_cell | 1.62316401 |
| 38 | MP0005075_abnormal_melanosome_morpholog | 1.56827028 |
| 39 | MP0002006_tumorigenesis | 1.53559790 |
| 40 | MP0002138_abnormal_hepatobiliary_system | 1.52941709 |
| 41 | MP0004947_skin_inflammation | 1.49568419 |
| 42 | MP0003303_peritoneal_inflammation | 1.45671356 |
| 43 | MP0005310_abnormal_salivary_gland | 1.39859633 |
| 44 | MP0002396_abnormal_hematopoietic_system | 1.34143696 |
| 45 | MP0001663_abnormal_digestive_system | 1.33911648 |
| 46 | MP0003172_abnormal_lysosome_physiology | 1.26294975 |
| 47 | MP0003045_fibrosis | 1.25483248 |
| 48 | MP0000490_abnormal_crypts_of | 1.23741093 |
| 49 | MP0001851_eye_inflammation | 1.21200918 |
| 50 | MP0002277_abnormal_respiratory_mucosa | 1.16835719 |
| 51 | MP0008469_abnormal_protein_level | 1.16216592 |
| 52 | MP0003300_gastrointestinal_ulcer | 1.15094253 |
| 53 | MP0002163_abnormal_gland_morphology | 0.99056218 |
| 54 | MP0003183_abnormal_peptide_metabolism | 0.93958598 |
| 55 | MP0005670_abnormal_white_adipose | 0.91778576 |
| 56 | MP0001533_abnormal_skeleton_physiology | 0.89775914 |
| 57 | MP0008057_abnormal_DNA_replication | 0.88431790 |
| 58 | MP0009764_decreased_sensitivity_to | 0.87813031 |
| 59 | MP0005381_digestive/alimentary_phenotyp | 0.86620960 |
| 60 | MP0005464_abnormal_platelet_physiology | 0.80103520 |
| 61 | MP0001853_heart_inflammation | 0.78193760 |
| 62 | MP0002693_abnormal_pancreas_physiology | 0.76621867 |
| 63 | MP0003448_altered_tumor_morphology | 0.76281533 |
| 64 | MP0005379_endocrine/exocrine_gland_phen | 0.70877096 |
| 65 | MP0008961_abnormal_basal_metabolism | 0.69920496 |
| 66 | MP0005166_decreased_susceptibility_to | 0.69126743 |
| 67 | MP0000858_altered_metastatic_potential | 0.68598943 |
| 68 | MP0008877_abnormal_DNA_methylation | 0.63151570 |
| 69 | MP0003329_amyloid_beta_deposits | 0.61096445 |
| 70 | MP0000604_amyloidosis | 0.60654222 |
| 71 | MP0005360_urolithiasis | 0.60164825 |
| 72 | MP0002009_preneoplasia | 0.59792945 |
| 73 | MP0002019_abnormal_tumor_incidence | 0.59765947 |
| 74 | MP0003011_delayed_dark_adaptation | 0.54452529 |
| 75 | MP0004883_abnormal_blood_vessel | 0.52392040 |
| 76 | MP0001958_emphysema | 0.52132209 |
| 77 | MP0009763_increased_sensitivity_to | 0.51328393 |
| 78 | MP0006072_abnormal_retinal_apoptosis | 0.48910509 |
| 79 | MP0003191_abnormal_cellular_cholesterol | 0.48105035 |
| 80 | MP0005451_abnormal_body_composition | 0.46684261 |
| 81 | MP0002132_abnormal_respiratory_system | 0.46625968 |
| 82 | MP0000609_abnormal_liver_physiology | 0.46624973 |
| 83 | MP0004142_abnormal_muscle_tone | 0.46202048 |
| 84 | MP0002136_abnormal_kidney_physiology | 0.45592393 |
| 85 | MP0004808_abnormal_hematopoietic_stem | 0.44363667 |
| 86 | MP0009643_abnormal_urine_homeostasis | 0.44216595 |
| 87 | MP0008569_lethality_at_weaning | 0.41525204 |
| 88 | MP0005084_abnormal_gallbladder_morpholo | 0.41352955 |
| 89 | MP0003795_abnormal_bone_structure | 0.41179760 |
| 90 | MP0003252_abnormal_bile_duct | 0.39924795 |
| 91 | MP0001765_abnormal_ion_homeostasis | 0.38367087 |
| 92 | MP0005535_abnormal_body_temperature | 0.34736916 |
| 93 | MP0002998_abnormal_bone_remodeling | 0.34011409 |
| 94 | MP0001919_abnormal_reproductive_system | 0.33616017 |
| 95 | MP0001346_abnormal_lacrimal_gland | 0.33410720 |
| 96 | MP0005645_abnormal_hypothalamus_physiol | 0.32566387 |
| 97 | MP0003828_pulmonary_edema | 0.31072145 |
| 98 | MP0009765_abnormal_xenobiotic_induced | 0.30789030 |
| 99 | MP0000313_abnormal_cell_death | 0.30773478 |
| 100 | MP0002168_other_aberrant_phenotype | 0.30321573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 7.34617518 |
| 2 | T lymphocytopenia (HP:0005403) | 7.19524548 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.80501043 |
| 4 | Recurrent cutaneous fungal infections (HP:0011370) | 6.75046229 |
| 5 | Chronic mucocutaneous candidiasis (HP:0002728) | 6.75046229 |
| 6 | Abnormality of T cell number (HP:0011839) | 6.54384005 |
| 7 | Increased IgM level (HP:0003496) | 5.59504068 |
| 8 | Chronic diarrhea (HP:0002028) | 5.59349179 |
| 9 | Recurrent fungal infections (HP:0002841) | 5.50980579 |
| 10 | IgG deficiency (HP:0004315) | 5.10325131 |
| 11 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 5.06400018 |
| 12 | Abnormality of T cells (HP:0002843) | 5.04504437 |
| 13 | Dyschromatopsia (HP:0007641) | 4.87423781 |
| 14 | Myositis (HP:0100614) | 4.37520490 |
| 15 | Autoimmune hemolytic anemia (HP:0001890) | 4.07429473 |
| 16 | Neonatal hypoglycemia (HP:0001998) | 4.05082191 |
| 17 | Retrobulbar optic neuritis (HP:0100654) | 3.94583322 |
| 18 | Optic neuritis (HP:0100653) | 3.94583322 |
| 19 | Recurrent skin infections (HP:0001581) | 3.89749779 |
| 20 | Cheilitis (HP:0100825) | 3.78989245 |
| 21 | Orchitis (HP:0100796) | 3.70057857 |
| 22 | Hemoptysis (HP:0002105) | 3.63145610 |
| 23 | Encephalitis (HP:0002383) | 3.57486097 |
| 24 | Vitreoretinal degeneration (HP:0000655) | 3.50629281 |
| 25 | IgA deficiency (HP:0002720) | 3.44384720 |
| 26 | Recurrent viral infections (HP:0004429) | 3.39229438 |
| 27 | Joint swelling (HP:0001386) | 3.36639642 |
| 28 | Severe combined immunodeficiency (HP:0004430) | 3.31737800 |
| 29 | Abnormality of T cell physiology (HP:0011840) | 3.24989650 |
| 30 | Recurrent bronchitis (HP:0002837) | 3.24884908 |
| 31 | Eczematoid dermatitis (HP:0000976) | 3.21109456 |
| 32 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.19659928 |
| 33 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.07915991 |
| 34 | Lymphopenia (HP:0001888) | 3.02063527 |
| 35 | Acute hepatic failure (HP:0006554) | 2.95316678 |
| 36 | Meningitis (HP:0001287) | 2.91285468 |
| 37 | Hypoproteinemia (HP:0003075) | 2.90610261 |
| 38 | Keratoconjunctivitis sicca (HP:0001097) | 2.88182657 |
| 39 | Pustule (HP:0200039) | 2.84706171 |
| 40 | Pigmentary retinal degeneration (HP:0001146) | 2.84541559 |
| 41 | Abnormality of macrophages (HP:0004311) | 2.83469854 |
| 42 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.82235028 |
| 43 | Abnormality of the fingertips (HP:0001211) | 2.81123793 |
| 44 | Cellular immunodeficiency (HP:0005374) | 2.80762397 |
| 45 | Keratoconjunctivitis (HP:0001096) | 2.80312568 |
| 46 | Hypergammaglobulinemia (HP:0010702) | 2.76717920 |
| 47 | Recurrent bacterial skin infections (HP:0005406) | 2.70928082 |
| 48 | Pulmonary infiltrates (HP:0002113) | 2.69523531 |
| 49 | IgM deficiency (HP:0002850) | 2.65725654 |
| 50 | Alveolar cell carcinoma (HP:0006519) | 2.65014164 |
| 51 | Hypochromic microcytic anemia (HP:0004840) | 2.61609813 |
| 52 | Recurrent abscess formation (HP:0002722) | 2.57615452 |
| 53 | Combined immunodeficiency (HP:0005387) | 2.50568885 |
| 54 | Pancytopenia (HP:0001876) | 2.49709616 |
| 55 | Lymphoma (HP:0002665) | 2.47094696 |
| 56 | Vasculitis (HP:0002633) | 2.46072362 |
| 57 | Hypoplasia of the thymus (HP:0000778) | 2.43005455 |
| 58 | Gastrointestinal infarctions (HP:0005244) | 2.37542393 |
| 59 | Hypochromic anemia (HP:0001931) | 2.36399521 |
| 60 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.34039809 |
| 61 | Skin rash (HP:0000988) | 2.30320546 |
| 62 | Colon cancer (HP:0003003) | 2.29367055 |
| 63 | Aplastic anemia (HP:0001915) | 2.25154845 |
| 64 | Mediastinal lymphadenopathy (HP:0100721) | 2.24367418 |
| 65 | Leukocytosis (HP:0001974) | 2.20714083 |
| 66 | Abnormality of eosinophils (HP:0001879) | 2.20065075 |
| 67 | Panhypogammaglobulinemia (HP:0003139) | 2.19849865 |
| 68 | 3-Methylglutaconic aciduria (HP:0003535) | 2.16007339 |
| 69 | Abnormality of the endocardium (HP:0004306) | 2.12300736 |
| 70 | Basal cell carcinoma (HP:0002671) | 2.06639417 |
| 71 | Inflammation of the large intestine (HP:0002037) | 2.05455251 |
| 72 | Hepatosplenomegaly (HP:0001433) | 2.03549579 |
| 73 | Thyroiditis (HP:0100646) | 2.02664100 |
| 74 | Micronodular cirrhosis (HP:0001413) | 1.94033109 |
| 75 | Microcytic anemia (HP:0001935) | 1.91940431 |
| 76 | Gastrointestinal inflammation (HP:0004386) | 1.91930003 |
| 77 | Gangrene (HP:0100758) | 1.89943477 |
| 78 | Papilledema (HP:0001085) | 1.89478914 |
| 79 | Agammaglobulinemia (HP:0004432) | 1.85361496 |
| 80 | Bronchitis (HP:0012387) | 1.81704453 |
| 81 | Mutism (HP:0002300) | 1.81620223 |
| 82 | Anorexia (HP:0002039) | 1.80221679 |
| 83 | Obstructive lung disease (HP:0006536) | 1.78795696 |
| 84 | Chronic obstructive pulmonary disease (HP:0006510) | 1.78795696 |
| 85 | Hepatitis (HP:0012115) | 1.78535845 |
| 86 | Chronic otitis media (HP:0000389) | 1.78231120 |
| 87 | Abolished electroretinogram (ERG) (HP:0000550) | 1.78149865 |
| 88 | B lymphocytopenia (HP:0010976) | 1.72933084 |
| 89 | Granulocytopenia (HP:0001913) | 1.71740958 |
| 90 | Amaurosis fugax (HP:0100576) | 1.71392383 |
| 91 | Pulmonary embolism (HP:0002204) | 1.71349307 |
| 92 | Abnormality of B cell number (HP:0010975) | 1.71250382 |
| 93 | Slow saccadic eye movements (HP:0000514) | 1.71241199 |
| 94 | Scanning speech (HP:0002168) | 1.70474894 |
| 95 | Stomach cancer (HP:0012126) | 1.70370284 |
| 96 | Palpitations (HP:0001962) | 1.70266294 |
| 97 | Progressive inability to walk (HP:0002505) | 1.66766347 |
| 98 | Resting tremor (HP:0002322) | 1.66586827 |
| 99 | Abnormality of the pleura (HP:0002103) | 1.65766861 |
| 100 | Chest pain (HP:0100749) | 1.65241189 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 9.60771153 |
| 2 | MAP4K1 | 4.45454190 |
| 3 | ITK | 2.97583130 |
| 4 | FES | 2.81706822 |
| 5 | TYK2 | 2.71559726 |
| 6 | TEC | 2.38285370 |
| 7 | TAOK3 | 2.27084213 |
| 8 | SIK3 | 2.26606874 |
| 9 | TYRO3 | 2.26168003 |
| 10 | BTK | 2.24746501 |
| 11 | RIPK4 | 2.13420019 |
| 12 | TAF1 | 2.02040613 |
| 13 | CSK | 1.86485036 |
| 14 | HCK | 1.78625196 |
| 15 | LCK | 1.57024592 |
| 16 | GRK6 | 1.55915107 |
| 17 | SYK | 1.53807957 |
| 18 | GRK7 | 1.47617219 |
| 19 | IKBKE | 1.47002238 |
| 20 | NLK | 1.46597550 |
| 21 | MOS | 1.44655965 |
| 22 | CLK1 | 1.41709380 |
| 23 | MAP3K12 | 1.33255308 |
| 24 | MAP3K13 | 1.31334616 |
| 25 | LYN | 1.30533199 |
| 26 | JAK3 | 1.23151119 |
| 27 | EPHB1 | 1.22971542 |
| 28 | JAK2 | 1.22905911 |
| 29 | PASK | 1.19575639 |
| 30 | MAP2K6 | 1.12527405 |
| 31 | IRAK4 | 1.11965921 |
| 32 | PRKCQ | 1.11536205 |
| 33 | VRK2 | 1.10132738 |
| 34 | ZAP70 | 1.09882891 |
| 35 | FGFR4 | 1.06758840 |
| 36 | KDR | 1.06262169 |
| 37 | IKBKB | 1.03879475 |
| 38 | PTK6 | 1.01506167 |
| 39 | STK10 | 0.99967490 |
| 40 | JAK1 | 0.97917774 |
| 41 | CAMKK2 | 0.96613765 |
| 42 | MST4 | 0.96247702 |
| 43 | TGFBR2 | 0.91196372 |
| 44 | MAP3K3 | 0.86892851 |
| 45 | MAP2K3 | 0.83479069 |
| 46 | TBK1 | 0.81362130 |
| 47 | MARK3 | 0.68890172 |
| 48 | BCR | 0.65787695 |
| 49 | PDK1 | 0.65549760 |
| 50 | CSF1R | 0.64470384 |
| 51 | HIPK2 | 0.63512458 |
| 52 | NTRK2 | 0.63010205 |
| 53 | TRIM28 | 0.62179038 |
| 54 | TNK2 | 0.62135782 |
| 55 | FYN | 0.58813386 |
| 56 | GRK5 | 0.58614849 |
| 57 | FGFR3 | 0.58504707 |
| 58 | SIK2 | 0.56224776 |
| 59 | MAP3K14 | 0.56146655 |
| 60 | MAP3K11 | 0.55352183 |
| 61 | CAMKK1 | 0.54642047 |
| 62 | VRK1 | 0.54407338 |
| 63 | CDK4 | 0.52816973 |
| 64 | PDGFRB | 0.52243934 |
| 65 | PRKCH | 0.51853234 |
| 66 | ADRBK2 | 0.50021009 |
| 67 | KIT | 0.49071991 |
| 68 | PTK2B | 0.47928234 |
| 69 | MAPK11 | 0.47175569 |
| 70 | SMG1 | 0.46309555 |
| 71 | IGF1R | 0.44705936 |
| 72 | NUAK1 | 0.43678894 |
| 73 | NEK6 | 0.42691446 |
| 74 | IRAK1 | 0.42089964 |
| 75 | BLK | 0.38944575 |
| 76 | PRPF4B | 0.38506878 |
| 77 | INSR | 0.36974993 |
| 78 | ERN1 | 0.36223525 |
| 79 | MAPKAPK2 | 0.35287782 |
| 80 | KSR2 | 0.34913659 |
| 81 | MAP3K1 | 0.34589359 |
| 82 | EPHB2 | 0.30195372 |
| 83 | SCYL2 | 0.27924436 |
| 84 | CCNB1 | 0.27121422 |
| 85 | TRPM7 | 0.27113978 |
| 86 | FGR | 0.26570203 |
| 87 | EPHA3 | 0.25821340 |
| 88 | GRK1 | 0.24665956 |
| 89 | STK38 | 0.20434383 |
| 90 | MAP3K8 | 0.19989017 |
| 91 | YES1 | 0.18828400 |
| 92 | TAOK1 | 0.16434426 |
| 93 | PIM1 | 0.16288843 |
| 94 | TAOK2 | 0.16075863 |
| 95 | CHUK | 0.15792934 |
| 96 | MAPK12 | 0.15605987 |
| 97 | PRKACG | 0.14938439 |
| 98 | MAPK3 | 0.14886583 |
| 99 | MARK2 | 0.12332692 |
| 100 | PDK2 | 0.10897200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.55255679 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 4.31302013 |
| 3 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.86028745 |
| 4 | Measles_Homo sapiens_hsa05162 | 3.19351210 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.12067650 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.12060076 |
| 7 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.99389741 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.89291167 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.79281399 |
| 10 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.72262132 |
| 11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.14921159 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.14528695 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.13655599 |
| 14 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 2.07512712 |
| 15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.05683642 |
| 16 | Viral myocarditis_Homo sapiens_hsa05416 | 1.99433563 |
| 17 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.83407224 |
| 18 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.69227879 |
| 19 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.62587305 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.60005389 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.57874921 |
| 22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.44881969 |
| 23 | Hepatitis B_Homo sapiens_hsa05161 | 1.25319870 |
| 24 | RNA polymerase_Homo sapiens_hsa03020 | 1.23621150 |
| 25 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.21353657 |
| 26 | Leishmaniasis_Homo sapiens_hsa05140 | 1.18554063 |
| 27 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.18456114 |
| 28 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.18006859 |
| 29 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.15015128 |
| 30 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.11054478 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.08728360 |
| 32 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.08581388 |
| 33 | HTLV-I infection_Homo sapiens_hsa05166 | 1.06341301 |
| 34 | Protein export_Homo sapiens_hsa03060 | 1.05035893 |
| 35 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.02551613 |
| 36 | Malaria_Homo sapiens_hsa05144 | 1.01089592 |
| 37 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.00652510 |
| 38 | Platelet activation_Homo sapiens_hsa04611 | 0.95559925 |
| 39 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.93552027 |
| 40 | Shigellosis_Homo sapiens_hsa05131 | 0.89257370 |
| 41 | Proteasome_Homo sapiens_hsa03050 | 0.87550792 |
| 42 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.86126153 |
| 43 | Influenza A_Homo sapiens_hsa05164 | 0.81628022 |
| 44 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.77887900 |
| 45 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.77388105 |
| 46 | Asthma_Homo sapiens_hsa05310 | 0.76225111 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.74975445 |
| 48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.71718940 |
| 49 | Apoptosis_Homo sapiens_hsa04210 | 0.71374900 |
| 50 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.67482955 |
| 51 | Tuberculosis_Homo sapiens_hsa05152 | 0.66341128 |
| 52 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.65757949 |
| 53 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.65329079 |
| 54 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64303629 |
| 55 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.63534601 |
| 56 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.57575528 |
| 57 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.56502722 |
| 58 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.55373978 |
| 59 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.55045966 |
| 60 | Legionellosis_Homo sapiens_hsa05134 | 0.54620589 |
| 61 | Hepatitis C_Homo sapiens_hsa05160 | 0.52261009 |
| 62 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.51717568 |
| 63 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.49421973 |
| 64 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.48551968 |
| 65 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.45228414 |
| 66 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43046833 |
| 67 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.42473570 |
| 68 | Colorectal cancer_Homo sapiens_hsa05210 | 0.42342772 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.41805208 |
| 70 | Endocytosis_Homo sapiens_hsa04144 | 0.40970956 |
| 71 | RNA degradation_Homo sapiens_hsa03018 | 0.40103536 |
| 72 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.39505091 |
| 73 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.39329835 |
| 74 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.37880558 |
| 75 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37237353 |
| 76 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32618124 |
| 77 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.32216921 |
| 78 | Circadian rhythm_Homo sapiens_hsa04710 | 0.29360973 |
| 79 | Salmonella infection_Homo sapiens_hsa05132 | 0.28841760 |
| 80 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.27884800 |
| 81 | Endometrial cancer_Homo sapiens_hsa05213 | 0.25906536 |
| 82 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.24047988 |
| 83 | Thyroid cancer_Homo sapiens_hsa05216 | 0.23578174 |
| 84 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.23154584 |
| 85 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.22998931 |
| 86 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.20680019 |
| 87 | Pertussis_Homo sapiens_hsa05133 | 0.20125889 |
| 88 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.19657650 |
| 89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.19632259 |
| 90 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.17780327 |
| 91 | Insulin resistance_Homo sapiens_hsa04931 | 0.16910914 |
| 92 | Phagosome_Homo sapiens_hsa04145 | 0.15681793 |
| 93 | Prion diseases_Homo sapiens_hsa05020 | 0.13314125 |
| 94 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.12701226 |
| 95 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.12560493 |
| 96 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.10830764 |
| 97 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.09515665 |
| 98 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.09321622 |
| 99 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.09226740 |
| 100 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.09194653 |

