

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 8.32298635 |
| 2 | negative thymic T cell selection (GO:0045060) | 7.41169094 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.68081234 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.56344978 |
| 5 | positive T cell selection (GO:0043368) | 6.53713277 |
| 6 | regulation of regulatory T cell differentiation (GO:0045589) | 6.23418767 |
| 7 | thymic T cell selection (GO:0045061) | 6.17838793 |
| 8 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.14141345 |
| 9 | T cell selection (GO:0045058) | 5.99478224 |
| 10 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.97978289 |
| 11 | positive thymic T cell selection (GO:0045059) | 5.96839814 |
| 12 | cytidine deamination (GO:0009972) | 5.94216380 |
| 13 | cytidine metabolic process (GO:0046087) | 5.94216380 |
| 14 | cytidine catabolic process (GO:0006216) | 5.94216380 |
| 15 | regulation of T cell tolerance induction (GO:0002664) | 5.91262476 |
| 16 | positive regulation of tolerance induction (GO:0002645) | 5.90081112 |
| 17 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.65247219 |
| 18 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.64460872 |
| 19 | cellular response to interleukin-15 (GO:0071350) | 5.58057177 |
| 20 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.53269163 |
| 21 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.49259410 |
| 22 | negative regulation of cell killing (GO:0031342) | 5.49259410 |
| 23 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.37296869 |
| 24 | response to interleukin-15 (GO:0070672) | 5.22319447 |
| 25 | leukocyte aggregation (GO:0070486) | 5.22161119 |
| 26 | T cell migration (GO:0072678) | 5.17956575 |
| 27 | regulation of tolerance induction (GO:0002643) | 5.06261004 |
| 28 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.90126165 |
| 29 | tolerance induction (GO:0002507) | 4.87470854 |
| 30 | regulation of gamma-delta T cell activation (GO:0046643) | 4.83937824 |
| 31 | DNA deamination (GO:0045006) | 4.77908271 |
| 32 | T cell receptor signaling pathway (GO:0050852) | 4.77344156 |
| 33 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.71895329 |
| 34 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.68866881 |
| 35 | positive regulation of B cell differentiation (GO:0045579) | 4.65627053 |
| 36 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.55881865 |
| 37 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.47749982 |
| 38 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.40113334 |
| 39 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.37035514 |
| 40 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.36658337 |
| 41 | antigen receptor-mediated signaling pathway (GO:0050851) | 4.32469622 |
| 42 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.30241924 |
| 43 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.28533022 |
| 44 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.28533022 |
| 45 | regulation of B cell differentiation (GO:0045577) | 4.21316291 |
| 46 | positive regulation of interleukin-4 production (GO:0032753) | 4.15942497 |
| 47 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.15119864 |
| 48 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.06849999 |
| 49 | actin nucleation (GO:0045010) | 4.03990286 |
| 50 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.02209113 |
| 51 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.94507864 |
| 52 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.93772564 |
| 53 | T cell costimulation (GO:0031295) | 3.91647426 |
| 54 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.89054823 |
| 55 | lymphocyte costimulation (GO:0031294) | 3.86866563 |
| 56 | negative regulation of T cell apoptotic process (GO:0070233) | 3.86803142 |
| 57 | interferon-gamma production (GO:0032609) | 3.86019696 |
| 58 | positive regulation of granulocyte differentiation (GO:0030854) | 3.83421105 |
| 59 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.79657844 |
| 60 | type I interferon signaling pathway (GO:0060337) | 3.77715103 |
| 61 | cellular response to type I interferon (GO:0071357) | 3.77715103 |
| 62 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.76905034 |
| 63 | signal complex assembly (GO:0007172) | 3.76722887 |
| 64 | response to type I interferon (GO:0034340) | 3.73319228 |
| 65 | positive regulation of cell killing (GO:0031343) | 3.69712636 |
| 66 | mast cell activation (GO:0045576) | 3.67925091 |
| 67 | regulation of cell killing (GO:0031341) | 3.64542859 |
| 68 | positive regulation of interleukin-2 production (GO:0032743) | 3.63475059 |
| 69 | negative regulation of T cell mediated immunity (GO:0002710) | 3.62108059 |
| 70 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.61927513 |
| 71 | negative regulation of viral genome replication (GO:0045071) | 3.56058426 |
| 72 | T cell differentiation (GO:0030217) | 3.52190796 |
| 73 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.51036626 |
| 74 | alpha-beta T cell differentiation (GO:0046632) | 3.48730401 |
| 75 | regulation of interleukin-4 production (GO:0032673) | 3.41735623 |
| 76 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.41310865 |
| 77 | positive regulation of T cell mediated immunity (GO:0002711) | 3.35047183 |
| 78 | activated T cell proliferation (GO:0050798) | 3.34379062 |
| 79 | lymphocyte migration (GO:0072676) | 3.33785256 |
| 80 | alpha-beta T cell activation (GO:0046631) | 3.22482080 |
| 81 | regulation of defense response to virus by virus (GO:0050690) | 3.21258656 |
| 82 | T cell activation (GO:0042110) | 3.20710729 |
| 83 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.14358204 |
| 84 | B cell receptor signaling pathway (GO:0050853) | 3.11061430 |
| 85 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.07645357 |
| 86 | T-helper cell differentiation (GO:0042093) | 3.06158082 |
| 87 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.06158082 |
| 88 | negative regulation of stress fiber assembly (GO:0051497) | 3.04945055 |
| 89 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.04163773 |
| 90 | regulation of T cell mediated immunity (GO:0002709) | 3.03496931 |
| 91 | T cell homeostasis (GO:0043029) | 3.02404959 |
| 92 | chemokine-mediated signaling pathway (GO:0070098) | 2.97792666 |
| 93 | immune response-activating cell surface receptor signaling pathway (GO:0002429) | 2.97788224 |
| 94 | response to interferon-beta (GO:0035456) | 2.96475438 |
| 95 | regulation of alpha-beta T cell activation (GO:0046634) | 2.94437794 |
| 96 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.94238512 |
| 97 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.94238512 |
| 98 | T cell differentiation involved in immune response (GO:0002292) | 2.94238512 |
| 99 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.94189215 |
| 100 | regulation of viral genome replication (GO:0045069) | 2.89442539 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.59231856 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.39440507 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.80879978 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.94824029 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.05878566 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.81085172 |
| 7 | MYB_26560356_Chip-Seq_TH2_Human | 3.63892523 |
| 8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.44950893 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.34449464 |
| 10 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.28780416 |
| 11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.21136038 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.04343304 |
| 13 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.82080019 |
| 14 | MYB_26560356_Chip-Seq_TH1_Human | 2.77595664 |
| 15 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.70514988 |
| 16 | MAF_26560356_Chip-Seq_TH1_Human | 2.65335238 |
| 17 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.63980814 |
| 18 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.62539217 |
| 19 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.61686437 |
| 20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.55920201 |
| 21 | UTX_26944678_Chip-Seq_JUKART_Human | 2.52890230 |
| 22 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.45765246 |
| 23 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.43125132 |
| 24 | GATA3_26560356_Chip-Seq_TH2_Human | 2.16326586 |
| 25 | MAF_26560356_Chip-Seq_TH2_Human | 2.08491907 |
| 26 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.06264969 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.04676877 |
| 28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.04273351 |
| 29 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.94863452 |
| 30 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.89542457 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.88874955 |
| 32 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.81082905 |
| 33 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80023324 |
| 34 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74233364 |
| 35 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.72927402 |
| 36 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.72634158 |
| 37 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.64619059 |
| 38 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.60432323 |
| 39 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.57858819 |
| 40 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.54303615 |
| 41 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.54260336 |
| 42 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.46797801 |
| 43 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.44017355 |
| 44 | SPI1_23127762_ChIP-Seq_K562_Human | 1.43726493 |
| 45 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.35428453 |
| 46 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.30759915 |
| 47 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.29315319 |
| 48 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.23078823 |
| 49 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.22861150 |
| 50 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.17971179 |
| 51 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.17096970 |
| 52 | MYC_22102868_ChIP-Seq_BL_Human | 1.14385629 |
| 53 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.11167446 |
| 54 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.09272806 |
| 55 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.05604407 |
| 56 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.05180059 |
| 57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05043255 |
| 58 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.03837682 |
| 59 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.03179113 |
| 60 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.03123946 |
| 61 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.02658961 |
| 62 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00395434 |
| 63 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.98049278 |
| 64 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92899776 |
| 65 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.92817641 |
| 66 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.90264716 |
| 67 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90000399 |
| 68 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89835293 |
| 69 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89706267 |
| 70 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88788872 |
| 71 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.88561027 |
| 72 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88047927 |
| 73 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85297294 |
| 74 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.84342277 |
| 75 | GATA3_26560356_Chip-Seq_TH1_Human | 0.83051885 |
| 76 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.82596234 |
| 77 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.81977678 |
| 78 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.80662565 |
| 79 | GATA1_22025678_ChIP-Seq_K562_Human | 0.79626027 |
| 80 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77260953 |
| 81 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.77059753 |
| 82 | GATA1_19941826_ChIP-Seq_K562_Human | 0.76507320 |
| 83 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.76160729 |
| 84 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.74954395 |
| 85 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.72634409 |
| 86 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.70917434 |
| 87 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70369566 |
| 88 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.69615602 |
| 89 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.68734944 |
| 90 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.68681311 |
| 91 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.68673786 |
| 92 | P300_27268052_Chip-Seq_Bcells_Human | 0.68492615 |
| 93 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.67417836 |
| 94 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.66807027 |
| 95 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.66603094 |
| 96 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.66570725 |
| 97 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.65377186 |
| 98 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.65258901 |
| 99 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.64924401 |
| 100 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.64717641 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.42591048 |
| 2 | MP0003763_abnormal_thymus_physiology | 4.83618204 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.70529761 |
| 4 | MP0001873_stomach_inflammation | 3.62989914 |
| 5 | MP0009785_altered_susceptibility_to | 3.41499712 |
| 6 | MP0001800_abnormal_humoral_immune | 3.30417471 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.25223803 |
| 8 | MP0003436_decreased_susceptibility_to | 3.15451804 |
| 9 | MP0003724_increased_susceptibility_to | 2.98990544 |
| 10 | MP0002166_altered_tumor_susceptibility | 2.91217869 |
| 11 | MP0009333_abnormal_splenocyte_physiolog | 2.88824453 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.81852570 |
| 13 | MP0002723_abnormal_immune_serum | 2.78902317 |
| 14 | MP0001819_abnormal_immune_cell | 2.77305064 |
| 15 | MP0005025_abnormal_response_to | 2.68484624 |
| 16 | MP0001790_abnormal_immune_system | 2.60759386 |
| 17 | MP0005387_immune_system_phenotype | 2.60759386 |
| 18 | MP0000685_abnormal_immune_system | 2.53581862 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.51170227 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.45611398 |
| 21 | MP0003866_abnormal_defecation | 2.44829376 |
| 22 | MP0002398_abnormal_bone_marrow | 2.41113962 |
| 23 | MP0000703_abnormal_thymus_morphology | 2.39989964 |
| 24 | MP0002405_respiratory_system_inflammati | 2.38441141 |
| 25 | MP0002009_preneoplasia | 2.28332208 |
| 26 | MP0000716_abnormal_immune_system | 2.27590417 |
| 27 | MP0004947_skin_inflammation | 2.19830034 |
| 28 | MP0010155_abnormal_intestine_physiology | 2.08723866 |
| 29 | MP0002419_abnormal_innate_immunity | 2.06810154 |
| 30 | MP0002006_tumorigenesis | 2.04540465 |
| 31 | MP0000465_gastrointestinal_hemorrhage | 2.01320702 |
| 32 | MP0002933_joint_inflammation | 2.01095231 |
| 33 | MP0004381_abnormal_hair_follicle | 1.95788111 |
| 34 | MP0002722_abnormal_immune_system | 1.95288223 |
| 35 | MP0006082_CNS_inflammation | 1.94774588 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.93228083 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.73004191 |
| 38 | MP0002429_abnormal_blood_cell | 1.72024159 |
| 39 | MP0005464_abnormal_platelet_physiology | 1.66839906 |
| 40 | MP0005075_abnormal_melanosome_morpholog | 1.57805502 |
| 41 | MP0005310_abnormal_salivary_gland | 1.51672775 |
| 42 | MP0001533_abnormal_skeleton_physiology | 1.51152990 |
| 43 | MP0003045_fibrosis | 1.47184955 |
| 44 | MP0001853_heart_inflammation | 1.46955198 |
| 45 | MP0002277_abnormal_respiratory_mucosa | 1.32492613 |
| 46 | MP0008469_abnormal_protein_level | 1.30291025 |
| 47 | MP0009764_decreased_sensitivity_to | 1.25238311 |
| 48 | MP0003300_gastrointestinal_ulcer | 1.18456416 |
| 49 | MP0003448_altered_tumor_morphology | 1.09622872 |
| 50 | MP0005645_abnormal_hypothalamus_physiol | 1.08585486 |
| 51 | MP0002132_abnormal_respiratory_system | 1.05302417 |
| 52 | MP0005166_decreased_susceptibility_to | 1.02049403 |
| 53 | MP0009763_increased_sensitivity_to | 1.01187632 |
| 54 | MP0002138_abnormal_hepatobiliary_system | 0.98435262 |
| 55 | MP0001851_eye_inflammation | 0.97909709 |
| 56 | MP0000858_altered_metastatic_potential | 0.94291417 |
| 57 | MP0002163_abnormal_gland_morphology | 0.94079852 |
| 58 | MP0001348_abnormal_lacrimal_gland | 0.93891579 |
| 59 | MP0008995_early_reproductive_senescence | 0.88348067 |
| 60 | MP0003191_abnormal_cellular_cholesterol | 0.86229453 |
| 61 | MP0002693_abnormal_pancreas_physiology | 0.85536973 |
| 62 | MP0001663_abnormal_digestive_system | 0.80665884 |
| 63 | MP0001986_abnormal_taste_sensitivity | 0.79899684 |
| 64 | MP0002396_abnormal_hematopoietic_system | 0.79577473 |
| 65 | MP0002019_abnormal_tumor_incidence | 0.78558871 |
| 66 | MP0000490_abnormal_crypts_of | 0.78472404 |
| 67 | MP0002998_abnormal_bone_remodeling | 0.75659233 |
| 68 | MP0002653_abnormal_ependyma_morphology | 0.73537599 |
| 69 | MP0003786_premature_aging | 0.73519850 |
| 70 | MP0001919_abnormal_reproductive_system | 0.68542478 |
| 71 | MP0003075_altered_response_to | 0.64884338 |
| 72 | MP0003252_abnormal_bile_duct | 0.64178925 |
| 73 | MP0004130_abnormal_muscle_cell | 0.62146642 |
| 74 | MP0002102_abnormal_ear_morphology | 0.62065683 |
| 75 | MP0001764_abnormal_homeostasis | 0.59967333 |
| 76 | MP0001243_abnormal_dermal_layer | 0.58012286 |
| 77 | MP0003303_peritoneal_inflammation | 0.56513174 |
| 78 | MP0002136_abnormal_kidney_physiology | 0.56387758 |
| 79 | MP0004883_abnormal_blood_vessel | 0.55526423 |
| 80 | MP0005390_skeleton_phenotype | 0.52953522 |
| 81 | MP0003806_abnormal_nucleotide_metabolis | 0.52853481 |
| 82 | MP0002876_abnormal_thyroid_physiology | 0.52154518 |
| 83 | MP0001765_abnormal_ion_homeostasis | 0.52004861 |
| 84 | MP0003795_abnormal_bone_structure | 0.51007993 |
| 85 | MP0009643_abnormal_urine_homeostasis | 0.50468092 |
| 86 | MP0001501_abnormal_sleep_pattern | 0.50373774 |
| 87 | MP0009765_abnormal_xenobiotic_induced | 0.47958251 |
| 88 | MP0000249_abnormal_blood_vessel | 0.47134651 |
| 89 | MP0003646_muscle_fatigue | 0.46412439 |
| 90 | MP0001905_abnormal_dopamine_level | 0.44954215 |
| 91 | MP0003787_abnormal_imprinting | 0.42572249 |
| 92 | MP0009840_abnormal_foam_cell | 0.42504748 |
| 93 | MP0002168_other_aberrant_phenotype | 0.42333773 |
| 94 | MP0008877_abnormal_DNA_methylation | 0.41863230 |
| 95 | MP0005381_digestive/alimentary_phenotyp | 0.41243495 |
| 96 | MP0008873_increased_physiological_sensi | 0.41170277 |
| 97 | MP0005379_endocrine/exocrine_gland_phen | 0.38250396 |
| 98 | MP0004134_abnormal_chest_morphology | 0.37543358 |
| 99 | MP0009642_abnormal_blood_homeostasis | 0.37273889 |
| 100 | MP0000477_abnormal_intestine_morphology | 0.35288047 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune hemolytic anemia (HP:0001890) | 6.75089142 |
| 2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.70441349 |
| 3 | T lymphocytopenia (HP:0005403) | 6.38034683 |
| 4 | Abnormality of T cell number (HP:0011839) | 5.89267626 |
| 5 | Stomatitis (HP:0010280) | 5.84391912 |
| 6 | Severe combined immunodeficiency (HP:0004430) | 5.83788002 |
| 7 | IgG deficiency (HP:0004315) | 5.42710000 |
| 8 | Aplastic anemia (HP:0001915) | 4.84488285 |
| 9 | Combined immunodeficiency (HP:0005387) | 4.68072321 |
| 10 | Eczematoid dermatitis (HP:0000976) | 4.55706847 |
| 11 | Abnormality of T cells (HP:0002843) | 4.49306982 |
| 12 | Increased IgM level (HP:0003496) | 4.31990028 |
| 13 | Panhypogammaglobulinemia (HP:0003139) | 4.18002694 |
| 14 | Hypoproteinemia (HP:0003075) | 4.16967603 |
| 15 | Recurrent fungal infections (HP:0002841) | 4.03324309 |
| 16 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.78721717 |
| 17 | Chronic diarrhea (HP:0002028) | 3.76804979 |
| 18 | Abnormality of the prostate (HP:0008775) | 3.71920572 |
| 19 | Thyroiditis (HP:0100646) | 3.65858982 |
| 20 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.65452704 |
| 21 | Recurrent cutaneous fungal infections (HP:0011370) | 3.65452704 |
| 22 | Gastrointestinal infarctions (HP:0005244) | 3.61999136 |
| 23 | Encephalitis (HP:0002383) | 3.58258489 |
| 24 | Meningitis (HP:0001287) | 3.57706756 |
| 25 | Myositis (HP:0100614) | 3.55165312 |
| 26 | Chronic obstructive pulmonary disease (HP:0006510) | 3.54242926 |
| 27 | Obstructive lung disease (HP:0006536) | 3.54242926 |
| 28 | Abnormality of eosinophils (HP:0001879) | 3.53462047 |
| 29 | Recurrent bronchitis (HP:0002837) | 3.37148370 |
| 30 | IgM deficiency (HP:0002850) | 3.33113339 |
| 31 | Abnormality of macrophages (HP:0004311) | 3.25903474 |
| 32 | Leukocytosis (HP:0001974) | 3.23431477 |
| 33 | Recurrent abscess formation (HP:0002722) | 3.17908398 |
| 34 | Lymphopenia (HP:0001888) | 3.17896276 |
| 35 | Recurrent bacterial skin infections (HP:0005406) | 3.17727985 |
| 36 | Vasculitis (HP:0002633) | 3.17075295 |
| 37 | Eosinophilia (HP:0001880) | 3.16789138 |
| 38 | Pulmonary infiltrates (HP:0002113) | 3.14288289 |
| 39 | Chest pain (HP:0100749) | 3.09416767 |
| 40 | Pustule (HP:0200039) | 3.08169249 |
| 41 | Granulocytopenia (HP:0001913) | 3.06332375 |
| 42 | Abnormality of T cell physiology (HP:0011840) | 2.98771437 |
| 43 | Hypergammaglobulinemia (HP:0010702) | 2.97517902 |
| 44 | Mediastinal lymphadenopathy (HP:0100721) | 2.96375775 |
| 45 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.95204416 |
| 46 | Recurrent viral infections (HP:0004429) | 2.93404627 |
| 47 | Retrobulbar optic neuritis (HP:0100654) | 2.88606814 |
| 48 | Optic neuritis (HP:0100653) | 2.88606814 |
| 49 | Hypoplasia of the thymus (HP:0000778) | 2.81391079 |
| 50 | Petechiae (HP:0000967) | 2.75661785 |
| 51 | Orchitis (HP:0100796) | 2.74302579 |
| 52 | Recurrent skin infections (HP:0001581) | 2.73042261 |
| 53 | Hemoptysis (HP:0002105) | 2.71013759 |
| 54 | Agammaglobulinemia (HP:0004432) | 2.70272313 |
| 55 | B lymphocytopenia (HP:0010976) | 2.69881734 |
| 56 | Abnormality of B cell number (HP:0010975) | 2.64549062 |
| 57 | Epistaxis (HP:0000421) | 2.63782155 |
| 58 | Gangrene (HP:0100758) | 2.61983934 |
| 59 | Inflammation of the large intestine (HP:0002037) | 2.51642960 |
| 60 | Joint swelling (HP:0001386) | 2.51089275 |
| 61 | Pulmonary embolism (HP:0002204) | 2.49416695 |
| 62 | Lymphoma (HP:0002665) | 2.42473632 |
| 63 | Increased IgE level (HP:0003212) | 2.41383110 |
| 64 | Papilledema (HP:0001085) | 2.37431431 |
| 65 | Gastrointestinal inflammation (HP:0004386) | 2.29012417 |
| 66 | Pancytopenia (HP:0001876) | 2.28981533 |
| 67 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.28947943 |
| 68 | Prolonged bleeding time (HP:0003010) | 2.28403629 |
| 69 | Abnormality of male internal genitalia (HP:0000022) | 2.27031470 |
| 70 | Prostate neoplasm (HP:0100787) | 2.26151996 |
| 71 | Ureteral stenosis (HP:0000071) | 2.23306318 |
| 72 | Hematochezia (HP:0002573) | 2.19174922 |
| 73 | Spontaneous hematomas (HP:0007420) | 2.14085229 |
| 74 | Bronchitis (HP:0012387) | 2.12790825 |
| 75 | Gingival bleeding (HP:0000225) | 2.10429726 |
| 76 | Pulmonary fibrosis (HP:0002206) | 2.09225075 |
| 77 | Acute hepatic failure (HP:0006554) | 2.08905765 |
| 78 | Autoimmune thrombocytopenia (HP:0001973) | 2.06611631 |
| 79 | Ureteral obstruction (HP:0006000) | 2.06609117 |
| 80 | Oral leukoplakia (HP:0002745) | 2.06217639 |
| 81 | Arterial thrombosis (HP:0004420) | 2.05907004 |
| 82 | Polyneuropathy (HP:0001271) | 2.04981503 |
| 83 | Keratoconjunctivitis (HP:0001096) | 2.04626623 |
| 84 | Keratoconjunctivitis sicca (HP:0001097) | 2.02587106 |
| 85 | Hypoalbuminemia (HP:0003073) | 2.00351325 |
| 86 | Abnormal albumin level (HP:0012116) | 2.00351325 |
| 87 | Neonatal respiratory distress (HP:0002643) | 1.97672795 |
| 88 | Microcytic anemia (HP:0001935) | 1.93480377 |
| 89 | Colitis (HP:0002583) | 1.91890473 |
| 90 | Anorexia (HP:0002039) | 1.90534351 |
| 91 | Abnormality of the pleura (HP:0002103) | 1.89596088 |
| 92 | Recurrent otitis media (HP:0000403) | 1.89524611 |
| 93 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.89045983 |
| 94 | Hypochromic anemia (HP:0001931) | 1.89039155 |
| 95 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.87525126 |
| 96 | Skin rash (HP:0000988) | 1.85678249 |
| 97 | Basal ganglia calcification (HP:0002135) | 1.85567122 |
| 98 | Amyotrophic lateral sclerosis (HP:0007354) | 1.85183123 |
| 99 | Urticaria (HP:0001025) | 1.84395325 |
| 100 | Congenital stationary night blindness (HP:0007642) | 1.84180292 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 7.22753846 |
| 2 | MAP4K1 | 5.21929382 |
| 3 | KDR | 3.85025229 |
| 4 | TAOK3 | 3.14240951 |
| 5 | ZAP70 | 2.85377175 |
| 6 | TESK2 | 2.83921289 |
| 7 | ITK | 2.82628132 |
| 8 | RIPK4 | 2.44865326 |
| 9 | GRK6 | 2.43380847 |
| 10 | TEC | 2.34142525 |
| 11 | FES | 2.28794022 |
| 12 | JAK3 | 2.17988959 |
| 13 | BTK | 2.07677553 |
| 14 | TYK2 | 2.04842649 |
| 15 | LCK | 1.92250669 |
| 16 | IKBKE | 1.88505921 |
| 17 | CSK | 1.88326729 |
| 18 | SYK | 1.85794018 |
| 19 | CSF1R | 1.55924910 |
| 20 | HCK | 1.51968497 |
| 21 | SCYL2 | 1.47375256 |
| 22 | JAK1 | 1.46257586 |
| 23 | MARK3 | 1.44188372 |
| 24 | NLK | 1.39646881 |
| 25 | CAMKK2 | 1.36585107 |
| 26 | MAP3K11 | 1.33902709 |
| 27 | PRKCQ | 1.31859847 |
| 28 | LYN | 1.31312082 |
| 29 | IRAK4 | 1.27642458 |
| 30 | TNK2 | 1.07003344 |
| 31 | BLK | 1.05850850 |
| 32 | JAK2 | 1.04928124 |
| 33 | PASK | 1.01851713 |
| 34 | PIM1 | 1.01084751 |
| 35 | ADRBK2 | 0.99431499 |
| 36 | IKBKB | 0.97179838 |
| 37 | TBK1 | 0.96503327 |
| 38 | KIT | 0.88661080 |
| 39 | FGFR4 | 0.86677947 |
| 40 | TLK1 | 0.86336370 |
| 41 | ZAK | 0.84837341 |
| 42 | FYN | 0.83815658 |
| 43 | CAMKK1 | 0.83513851 |
| 44 | TESK1 | 0.81390407 |
| 45 | LRRK2 | 0.79108971 |
| 46 | STK10 | 0.78350228 |
| 47 | MAP3K3 | 0.78143564 |
| 48 | SIK2 | 0.77146535 |
| 49 | TAOK2 | 0.76961670 |
| 50 | MAP3K13 | 0.76735936 |
| 51 | SIK3 | 0.75154505 |
| 52 | MAP3K10 | 0.73205502 |
| 53 | MAP3K14 | 0.71576523 |
| 54 | TAOK1 | 0.70424103 |
| 55 | GRK7 | 0.65921185 |
| 56 | IGF1R | 0.65106957 |
| 57 | FGFR3 | 0.60824289 |
| 58 | MAP2K6 | 0.60019670 |
| 59 | MAP3K5 | 0.58007560 |
| 60 | BMPR2 | 0.57243690 |
| 61 | CLK1 | 0.57135077 |
| 62 | CDK19 | 0.56385695 |
| 63 | MAPK11 | 0.56180136 |
| 64 | PRPF4B | 0.51331048 |
| 65 | TYRO3 | 0.50771291 |
| 66 | FGR | 0.50683195 |
| 67 | MAP2K3 | 0.48322729 |
| 68 | PDGFRB | 0.46418851 |
| 69 | MAP3K12 | 0.44267803 |
| 70 | INSR | 0.43653391 |
| 71 | FRK | 0.42655861 |
| 72 | MST4 | 0.42084624 |
| 73 | RPS6KA5 | 0.39927252 |
| 74 | PIK3CA | 0.39436752 |
| 75 | TRPM7 | 0.36496615 |
| 76 | HIPK2 | 0.36089230 |
| 77 | VRK1 | 0.34464703 |
| 78 | PDK1 | 0.32137512 |
| 79 | VRK2 | 0.32097070 |
| 80 | MAP3K1 | 0.30043176 |
| 81 | GRK1 | 0.28650400 |
| 82 | MAP4K2 | 0.28403728 |
| 83 | TIE1 | 0.27910487 |
| 84 | ABL1 | 0.27217750 |
| 85 | EPHB1 | 0.25924848 |
| 86 | ERBB3 | 0.25570476 |
| 87 | PIK3CG | 0.24911065 |
| 88 | EGFR | 0.22282034 |
| 89 | CDK4 | 0.21491941 |
| 90 | MAPK3 | 0.20705354 |
| 91 | PRKCH | 0.20366912 |
| 92 | ROCK1 | 0.19660863 |
| 93 | WNK4 | 0.18232270 |
| 94 | PRKCD | 0.17257259 |
| 95 | PTK2B | 0.17106887 |
| 96 | STK4 | 0.14012839 |
| 97 | PRKCA | 0.13705252 |
| 98 | MYLK | 0.13641130 |
| 99 | SRC | 0.13162145 |
| 100 | MAP3K7 | 0.12604538 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.98721851 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 4.09653163 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.40843399 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.37002735 |
| 5 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.23727038 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.08741417 |
| 7 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 3.04994095 |
| 8 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.85551379 |
| 9 | Measles_Homo sapiens_hsa05162 | 2.69401655 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.30964092 |
| 11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.99984214 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.98261319 |
| 13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.84424819 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.79734422 |
| 15 | Viral myocarditis_Homo sapiens_hsa05416 | 1.64034430 |
| 16 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.62592838 |
| 17 | Proteasome_Homo sapiens_hsa03050 | 1.59074893 |
| 18 | Malaria_Homo sapiens_hsa05144 | 1.54856203 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.52461698 |
| 20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.47700709 |
| 21 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.45245782 |
| 22 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.38014211 |
| 23 | Leishmaniasis_Homo sapiens_hsa05140 | 1.37145250 |
| 24 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.36682515 |
| 25 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.35627193 |
| 26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.29250677 |
| 27 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.28117438 |
| 28 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.27934116 |
| 29 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.23915987 |
| 30 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.22063307 |
| 31 | Shigellosis_Homo sapiens_hsa05131 | 1.17863819 |
| 32 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.16983961 |
| 33 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.13676972 |
| 34 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.13523900 |
| 35 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.06019641 |
| 36 | Asthma_Homo sapiens_hsa05310 | 0.99296841 |
| 37 | Platelet activation_Homo sapiens_hsa04611 | 0.97830642 |
| 38 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.85305824 |
| 39 | Influenza A_Homo sapiens_hsa05164 | 0.83382806 |
| 40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.82801559 |
| 41 | Tuberculosis_Homo sapiens_hsa05152 | 0.81951625 |
| 42 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.80918957 |
| 43 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.77186271 |
| 44 | Pertussis_Homo sapiens_hsa05133 | 0.74196582 |
| 45 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.73110876 |
| 46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.72919881 |
| 47 | HTLV-I infection_Homo sapiens_hsa05166 | 0.71854925 |
| 48 | Legionellosis_Homo sapiens_hsa05134 | 0.68350196 |
| 49 | Ribosome_Homo sapiens_hsa03010 | 0.67487580 |
| 50 | Salmonella infection_Homo sapiens_hsa05132 | 0.66680597 |
| 51 | Endocytosis_Homo sapiens_hsa04144 | 0.64892094 |
| 52 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.64251704 |
| 53 | Hepatitis B_Homo sapiens_hsa05161 | 0.63457040 |
| 54 | Phototransduction_Homo sapiens_hsa04744 | 0.62302809 |
| 55 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.60474108 |
| 56 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.59646876 |
| 57 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.56790418 |
| 58 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.54220361 |
| 59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53094360 |
| 60 | Apoptosis_Homo sapiens_hsa04210 | 0.53034340 |
| 61 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.49769483 |
| 62 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49329794 |
| 63 | Hepatitis C_Homo sapiens_hsa05160 | 0.48022978 |
| 64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.47057216 |
| 65 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.45873245 |
| 66 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45619899 |
| 67 | ABC transporters_Homo sapiens_hsa02010 | 0.45168905 |
| 68 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44103083 |
| 69 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.42722961 |
| 70 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.41373003 |
| 71 | Parkinsons disease_Homo sapiens_hsa05012 | 0.40654814 |
| 72 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.40110627 |
| 73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37622089 |
| 74 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.37599782 |
| 75 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.36394332 |
| 76 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.35643578 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31372680 |
| 78 | Phagosome_Homo sapiens_hsa04145 | 0.31214456 |
| 79 | Salivary secretion_Homo sapiens_hsa04970 | 0.30935332 |
| 80 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.30045139 |
| 81 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.29685886 |
| 82 | RNA degradation_Homo sapiens_hsa03018 | 0.26502647 |
| 83 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.25726762 |
| 84 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.25377517 |
| 85 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.25334481 |
| 86 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.23553223 |
| 87 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.22610100 |
| 88 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.22235198 |
| 89 | Renin secretion_Homo sapiens_hsa04924 | 0.21986383 |
| 90 | Alzheimers disease_Homo sapiens_hsa05010 | 0.19081706 |
| 91 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.19075517 |
| 92 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.17724744 |
| 93 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.16627879 |
| 94 | Peroxisome_Homo sapiens_hsa04146 | 0.16597561 |
| 95 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.14785663 |
| 96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.14159043 |
| 97 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.13858724 |
| 98 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.13264167 |
| 99 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.12658434 |
| 100 | RNA polymerase_Homo sapiens_hsa03020 | 0.12542147 |

