TRBJ1-1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)8.88380766
2positive regulation of gamma-delta T cell activation (GO:0046645)8.32381401
3negative thymic T cell selection (GO:0045060)7.95238810
4interferon-gamma production (GO:0032609)7.40738928
5positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)7.06046777
6negative regulation of cell killing (GO:0031342)6.97140152
7negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.97140152
8regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.95437350
9regulation of gamma-delta T cell differentiation (GO:0045586)6.86595859
10regulation of T cell tolerance induction (GO:0002664)6.83908515
11positive T cell selection (GO:0043368)6.72147331
12cytidine metabolic process (GO:0046087)6.69209190
13cytidine catabolic process (GO:0006216)6.69209190
14cytidine deamination (GO:0009972)6.69209190
15antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.66850925
16antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.66850925
17thymic T cell selection (GO:0045061)6.52956488
18T cell selection (GO:0045058)6.25987941
19regulation of gamma-delta T cell activation (GO:0046643)6.10313072
20positive thymic T cell selection (GO:0045059)5.99830318
21positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.96499448
22response to interleukin-15 (GO:0070672)5.87170865
23T cell migration (GO:0072678)5.83940650
24regulation of isotype switching to IgG isotypes (GO:0048302)5.82516057
25pyrimidine ribonucleoside catabolic process (GO:0046133)5.81209203
26T cell receptor signaling pathway (GO:0050852)5.78700952
27DNA deamination (GO:0045006)5.67242592
28cellular response to interleukin-15 (GO:0071350)5.64932084
29positive regulation of tolerance induction (GO:0002645)5.57802126
30positive regulation of B cell differentiation (GO:0045579)5.52113000
31antigen processing and presentation of endogenous antigen (GO:0019883)5.51397631
32positive regulation of alpha-beta T cell proliferation (GO:0046641)5.15436301
33T cell costimulation (GO:0031295)5.10605139
34regulation of alpha-beta T cell proliferation (GO:0046640)5.01769993
35regulation of natural killer cell mediated immunity (GO:0002715)5.00912351
36regulation of natural killer cell mediated cytotoxicity (GO:0042269)5.00912351
37lymphocyte costimulation (GO:0031294)5.00790452
38antigen receptor-mediated signaling pathway (GO:0050851)4.92404258
39leukocyte aggregation (GO:0070486)4.89331101
40regulation of tolerance induction (GO:0002643)4.86131124
41activated T cell proliferation (GO:0050798)4.84940946
42actin nucleation (GO:0045010)4.83884021
43mast cell activation (GO:0045576)4.83865650
44negative regulation of T cell apoptotic process (GO:0070233)4.83536998
45antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.73407169
46signal complex assembly (GO:0007172)4.68710904
47regulation of T cell receptor signaling pathway (GO:0050856)4.60210064
48response to pheromone (GO:0019236)4.49932860
49regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.48011841
50positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.45686628
51positive regulation of natural killer cell mediated immunity (GO:0002717)4.45686628
52V(D)J recombination (GO:0033151)4.36418332
53regulation of B cell receptor signaling pathway (GO:0050855)4.31554946
54regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.21685259
55regulation of interleukin-2 biosynthetic process (GO:0045076)4.17100734
56positive regulation of granulocyte differentiation (GO:0030854)4.07735153
57ribosomal small subunit assembly (GO:0000028)3.99480281
58positive regulation of interleukin-2 production (GO:0032743)3.99032634
59regulation of leukocyte mediated cytotoxicity (GO:0001910)3.97151958
60positive regulation of isotype switching (GO:0045830)3.86781415
61cellular response to interleukin-4 (GO:0071353)3.83701604
62positive regulation of immune response to tumor cell (GO:0002839)3.83409719
63regulation of immune response to tumor cell (GO:0002837)3.83409719
64regulation of response to tumor cell (GO:0002834)3.83409719
65positive regulation of response to tumor cell (GO:0002836)3.83409719
66regulation of regulatory T cell differentiation (GO:0045589)3.81675008
67positive regulation of B cell mediated immunity (GO:0002714)3.81353635
68positive regulation of immunoglobulin mediated immune response (GO:0002891)3.81353635
69mast cell activation involved in immune response (GO:0002279)3.78724875
70mast cell degranulation (GO:0043303)3.78724875
71positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.75772021
72T cell differentiation (GO:0030217)3.71383955
73immune response-activating cell surface receptor signaling pathway (GO:0002429)3.67563313
74positive regulation of interleukin-8 secretion (GO:2000484)3.67271622
75antigen processing and presentation via MHC class Ib (GO:0002475)3.65454089
76regulation of cell killing (GO:0031341)3.64795178
77negative regulation of T cell mediated immunity (GO:0002710)3.64347655
78positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.57281974
79negative regulation of T cell receptor signaling pathway (GO:0050860)3.55755954
80T cell activation (GO:0042110)3.54149506
81positive regulation of humoral immune response (GO:0002922)3.53668457
82positive regulation of cell killing (GO:0031343)3.49183755
83chemokine-mediated signaling pathway (GO:0070098)3.46334195
84lymphocyte migration (GO:0072676)3.43466656
85alpha-beta T cell activation (GO:0046631)3.42649067
86alpha-beta T cell differentiation (GO:0046632)3.41961630
87sequestering of actin monomers (GO:0042989)3.41522778
88response to interferon-beta (GO:0035456)3.41320656
89response to interleukin-4 (GO:0070670)3.41146965
90natural killer cell activation (GO:0030101)3.40871968
91positive regulation of defense response to virus by host (GO:0002230)3.40372967
92lymphocyte chemotaxis (GO:0048247)3.39926800
93regulation of activation of Janus kinase activity (GO:0010533)3.38454801
94regulation of immunoglobulin mediated immune response (GO:0002889)3.38164357
95T cell homeostasis (GO:0043029)3.37942134
96positive regulation of interleukin-4 production (GO:0032753)3.33837291
97positive regulation of immunoglobulin production (GO:0002639)3.32819023
98regulation of isotype switching (GO:0045191)3.32640763
99natural killer cell differentiation (GO:0001779)3.31800798
100negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.31440142
101Arp2/3 complex-mediated actin nucleation (GO:0034314)3.29575141
102regulation of B cell mediated immunity (GO:0002712)3.29165534
103T cell mediated immunity (GO:0002456)3.28852723
104negative regulation of lymphocyte apoptotic process (GO:0070229)3.28630518
105regulation of defense response to virus by virus (GO:0050690)3.27071444
106positive regulation of DNA recombination (GO:0045911)3.27031771
107leukocyte cell-cell adhesion (GO:0007159)3.26792038
108regulation of T cell apoptotic process (GO:0070232)3.24932219
109B cell receptor signaling pathway (GO:0050853)3.23692619
110regulation of response to interferon-gamma (GO:0060330)3.23508762
111negative regulation of stress fiber assembly (GO:0051497)3.17159928
112positive regulation of T cell mediated cytotoxicity (GO:0001916)3.16125309
113respiratory burst (GO:0045730)3.15367448
114regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.15335179
115regulation of interleukin-12 biosynthetic process (GO:0045075)3.13170980
116regulation of B cell differentiation (GO:0045577)3.12669166
117negative regulation of viral genome replication (GO:0045071)3.12312603
118regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.10968006
119negative regulation of execution phase of apoptosis (GO:1900118)3.10412658
120negative regulation of lymphocyte mediated immunity (GO:0002707)3.10220217
121positive regulation of calcium-mediated signaling (GO:0050850)3.09997206
122positive regulation of monocyte chemotaxis (GO:0090026)3.08836035
123regulation of interleukin-4 production (GO:0032673)3.07787779
124DNA unwinding involved in DNA replication (GO:0006268)3.07463399
125regulation of interleukin-2 production (GO:0032663)3.03827834
126regulation of immunoglobulin production (GO:0002637)3.01999387
127positive regulation of uterine smooth muscle contraction (GO:0070474)3.01482647
128regulation of T cell mediated cytotoxicity (GO:0001914)3.01047002
129positive regulation of T cell activation (GO:0050870)3.00145663
130negative regulation by host of viral transcription (GO:0043922)2.97106333
131positive regulation of T cell cytokine production (GO:0002726)2.97077196
132heterotypic cell-cell adhesion (GO:0034113)2.96156365
133viral transcription (GO:0019083)2.95902329
134regulation of alpha-beta T cell activation (GO:0046634)2.92308038
135regulation of calcium-mediated signaling (GO:0050848)2.91956038
136pyrimidine nucleoside catabolic process (GO:0046135)2.91913644
137regulation of interleukin-8 secretion (GO:2000482)2.91458569
138positive regulation of lamellipodium assembly (GO:0010592)2.90770520
139regulation of lymphocyte chemotaxis (GO:1901623)2.90360308

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.07704197
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.07280216
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.68567886
4MYC_22102868_ChIP-Seq_BL_Human3.55731825
5RUNX_20019798_ChIP-Seq_JUKART_Human3.39880304
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.37023112
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.33610357
8MYB_26560356_Chip-Seq_TH2_Human3.22233790
9FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.20962779
10STAT4_19710469_ChIP-ChIP_TH1__Mouse3.18674326
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.95106765
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.94872127
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.94839423
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.87274136
15MAF_26560356_Chip-Seq_TH1_Human2.82310824
16UTX_26944678_Chip-Seq_JUKART_Human2.71828214
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.54953423
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.52410832
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.51432421
20MYB_26560356_Chip-Seq_TH1_Human2.51097455
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.32112398
22EZH2_22144423_ChIP-Seq_EOC_Human2.29326657
23EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.25115139
24VDR_21846776_ChIP-Seq_THP-1_Human2.19146424
25GATA3_27048872_Chip-Seq_THYMUS_Human2.17177354
26CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.10685054
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.09954589
28IRF8_21731497_ChIP-ChIP_J774_Mouse1.95167578
29BP1_19119308_ChIP-ChIP_Hs578T_Human1.94349223
30RUNX1_22412390_ChIP-Seq_EML_Mouse1.93123842
31MAF_26560356_Chip-Seq_TH2_Human1.92077249
32NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.91037614
33KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.88069770
34E2F4_17652178_ChIP-ChIP_JURKAT_Human1.86594330
35ELF1_17652178_ChIP-ChIP_JURKAT_Human1.83437973
36SPI1_23547873_ChIP-Seq_NB4_Human1.81675196
37SCL_19346495_ChIP-Seq_HPC-7_Human1.81465171
38FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.81241081
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.79881091
40TCF7_22412390_ChIP-Seq_EML_Mouse1.79054072
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.77155715
42TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.74241640
43E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.68993665
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.67310083
45STAT6_21828071_ChIP-Seq_BEAS2B_Human1.66060399
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.63052855
47VDR_24763502_ChIP-Seq_THP-1_Human1.60744269
48RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.56596466
49KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.50584697
50SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.50210311
51RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47802955
52KDM2B_26808549_Chip-Seq_DND41_Human1.45986191
53MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.45751735
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44628683
55NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.43347606
56ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41042231
57BCL6_27268052_Chip-Seq_Bcells_Human1.36560839
58IRF8_27001747_Chip-Seq_BMDM_Mouse1.36033334
59BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35674451
60IGF1R_20145208_ChIP-Seq_DFB_Human1.32142756
61SPI1_23127762_ChIP-Seq_K562_Human1.31595655
62VDR_23849224_ChIP-Seq_CD4+_Human1.30213894
63CIITA_25753668_ChIP-Seq_RAJI_Human1.30138259
64FOXP3_21729870_ChIP-Seq_TREG_Human1.29871402
65AR_20517297_ChIP-Seq_VCAP_Human1.27715493
66TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.25097180
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22441505
68FLI1_27457419_Chip-Seq_LIVER_Mouse1.20510283
69GATA2_22383799_ChIP-Seq_G1ME_Mouse1.19866933
70GATA3_26560356_Chip-Seq_TH2_Human1.19329750
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.18623866
72VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16928616
73RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.16682214
74EGR1_19032775_ChIP-ChIP_M12_Human1.15662578
75FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.15567167
76HOXB4_20404135_ChIP-ChIP_EML_Mouse1.15496585
77EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15410359
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13024725
79E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.11375162
80NANOG_20526341_ChIP-Seq_ESCs_Human1.09613495
81MYC_19079543_ChIP-ChIP_MESCs_Mouse1.08260700
82PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07107528
83EST1_17652178_ChIP-ChIP_JURKAT_Human1.06348570
84MYC_18555785_ChIP-Seq_MESCs_Mouse1.04997996
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04937039
86TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04507488
87BCOR_27268052_Chip-Seq_Bcells_Human1.04351679
88GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03839401
89ELK1_19687146_ChIP-ChIP_HELA_Human1.03453968
90LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.01487318
91TAF15_26573619_Chip-Seq_HEK293_Human0.99159541
92EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.98989777
93ELF1_20517297_ChIP-Seq_JURKAT_Human0.98573202
94THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.98217498
95PU_27001747_Chip-Seq_BMDM_Mouse0.98050904
96XRN2_22483619_ChIP-Seq_HELA_Human0.97729211
97KDM2B_26808549_Chip-Seq_SUP-B15_Human0.95816068
98SPI1_20517297_ChIP-Seq_HL60_Human0.95737881
99SA1_27219007_Chip-Seq_Bcells_Human0.95730902
100NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.95424455
101RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94886278
102GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.93672565
103SOX2_21211035_ChIP-Seq_LN229_Human0.93507445
104P300_27268052_Chip-Seq_Bcells_Human0.93210292
105BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.92078512
106RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.90806299
107ELK3_25401928_ChIP-Seq_HUVEC_Human0.90126727
108CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89908734
109PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87897700
110KDM2B_26808549_Chip-Seq_JURKAT_Human0.86729043
111GATA1_22383799_ChIP-Seq_G1ME_Mouse0.86347671
112PU.1_20513432_ChIP-Seq_Bcells_Mouse0.86172324
113EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.85860984
114LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.85323093
115CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84040936
116CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.83294547
117SMAD_19615063_ChIP-ChIP_OVARY_Human0.82942771
118FOXA1_21572438_ChIP-Seq_LNCaP_Human0.82655655
119RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80674972
120FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80021577
121E2F1_21310950_ChIP-Seq_MCF-7_Human0.79137435
122SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.78638370
123GATA1_19941827_ChIP-Seq_MEL_Mouse0.78268648
124CTCF_20526341_ChIP-Seq_ESCs_Human0.78248080
125AR_21572438_ChIP-Seq_LNCaP_Human0.78005132
126CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77826900
127PCGF2_27294783_Chip-Seq_ESCs_Mouse0.77357670
128GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.77275642
129TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.77213240
130GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.77074311
131GATA3_26560356_Chip-Seq_TH1_Human0.76889974
132TAF2_19829295_ChIP-Seq_ESCs_Human0.76826011
133GABP_17652178_ChIP-ChIP_JURKAT_Human0.75942360
134PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.75879801
135GATA6_21074721_ChIP-Seq_CACO-2_Human0.75466808
136TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.73774871
137ERG_20517297_ChIP-Seq_VCAP_Human0.73395253
138GATA1_22025678_ChIP-Seq_K562_Human0.73371362
139MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.73035855
140ERA_21632823_ChIP-Seq_H3396_Human0.72598202
141E2F1_20622854_ChIP-Seq_HELA_Human0.71247359
142CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.70574407
143BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.70371251
144OCT4_20526341_ChIP-Seq_ESCs_Human0.70164095
145MYC_18358816_ChIP-ChIP_MESCs_Mouse0.68876856
146FOXA1_27270436_Chip-Seq_PROSTATE_Human0.68625075
147FOXA1_25329375_ChIP-Seq_VCAP_Human0.68625075
148MYC_19030024_ChIP-ChIP_MESCs_Mouse0.68545718
149NCOR_22424771_ChIP-Seq_293T_Human0.68341653
150MYC_19829295_ChIP-Seq_ESCs_Human0.66904793
151NFE2_27457419_Chip-Seq_LIVER_Mouse0.66902357
152MYC_18940864_ChIP-ChIP_HL60_Human0.65800101

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology5.74754862
2MP0005671_abnormal_response_to5.42558786
3MP0003011_delayed_dark_adaptation3.44936763
4MP0001835_abnormal_antigen_presentation3.27219893
5MP0000685_abnormal_immune_system3.27056775
6MP0009333_abnormal_splenocyte_physiolog3.21258078
7MP0000703_abnormal_thymus_morphology3.16963922
8MP0001800_abnormal_humoral_immune3.16667749
9MP0003646_muscle_fatigue3.13283346
10MP0002398_abnormal_bone_marrow3.09092854
11MP0002420_abnormal_adaptive_immunity2.99600962
12MP0001819_abnormal_immune_cell2.93928554
13MP0005000_abnormal_immune_tolerance2.71454726
14MP0002723_abnormal_immune_serum2.70795595
15MP0002166_altered_tumor_susceptibility2.67747115
16MP0003300_gastrointestinal_ulcer2.65505432
17MP0002722_abnormal_immune_system2.62847250
18MP0000716_abnormal_immune_system2.60656974
19MP0002396_abnormal_hematopoietic_system2.54928706
20MP0002405_respiratory_system_inflammati2.50666512
21MP0002452_abnormal_antigen_presenting2.48511717
22MP0009785_altered_susceptibility_to2.43732586
23MP0000689_abnormal_spleen_morphology2.42995340
24MP0005025_abnormal_response_to2.41864091
25MP0001790_abnormal_immune_system2.41434668
26MP0005387_immune_system_phenotype2.41434668
27MP0002638_abnormal_pupillary_reflex2.30907186
28MP0006082_CNS_inflammation2.29930868
29MP0002006_tumorigenesis2.28493687
30MP0005377_hearing/vestibular/ear_phenot2.17285749
31MP0003878_abnormal_ear_physiology2.17285749
32MP0002429_abnormal_blood_cell2.15167488
33MP0004947_skin_inflammation2.14472605
34MP0003436_decreased_susceptibility_to2.09986479
35MP0003866_abnormal_defecation1.98450236
36MP0002277_abnormal_respiratory_mucosa1.97442478
37MP0001873_stomach_inflammation1.94535872
38MP0010155_abnormal_intestine_physiology1.94216156
39MP0002148_abnormal_hypersensitivity_rea1.90753529
40MP0003724_increased_susceptibility_to1.89541087
41MP0002419_abnormal_innate_immunity1.84613670
42MP0005464_abnormal_platelet_physiology1.82333007
43MP0004381_abnormal_hair_follicle1.77222125
44MP0000858_altered_metastatic_potential1.72899786
45MP0002933_joint_inflammation1.70394500
46MP0004145_abnormal_muscle_electrophysio1.70024847
47MP0010352_gastrointestinal_tract_polyps1.70018279
48MP0001845_abnormal_inflammatory_respons1.65136956
49MP0003448_altered_tumor_morphology1.57159096
50MP0000465_gastrointestinal_hemorrhage1.55299244
51MP0004808_abnormal_hematopoietic_stem1.53923895
52MP0005645_abnormal_hypothalamus_physiol1.49464225
53MP0001853_heart_inflammation1.48860698
54MP0000372_irregular_coat_pigmentation1.44048156
55MP0005075_abnormal_melanosome_morpholog1.43910027
56MP0008057_abnormal_DNA_replication1.43552498
57MP0010094_abnormal_chromosome_stability1.40202294
58MP0003191_abnormal_cellular_cholesterol1.32643350
59MP0002019_abnormal_tumor_incidence1.31974253
60MP0005397_hematopoietic_system_phenotyp1.28905855
61MP0001545_abnormal_hematopoietic_system1.28905855
62MP0006054_spinal_hemorrhage1.25678801
63MP0003303_peritoneal_inflammation1.25208606
64MP0004957_abnormal_blastocyst_morpholog1.23564597
65MP0000490_abnormal_crypts_of1.19680556
66MP0001764_abnormal_homeostasis1.17804734
67MP0003077_abnormal_cell_cycle1.12399492
68MP0001542_abnormal_bone_strength1.06945850
69MP0003183_abnormal_peptide_metabolism1.06040947
70MP0004510_myositis1.05991832
71MP0005360_urolithiasis1.05700474
72MP0008469_abnormal_protein_level0.99479180
73MP0005253_abnormal_eye_physiology0.99259294
74MP0005410_abnormal_fertilization0.98905331
75MP0003693_abnormal_embryo_hatching0.97920530
76MP0002163_abnormal_gland_morphology0.97885647
77MP0005023_abnormal_wound_healing0.96370160
78MP0002102_abnormal_ear_morphology0.93347970
79MP0001765_abnormal_ion_homeostasis0.91964659
80MP0001919_abnormal_reproductive_system0.89854668
81MP0002138_abnormal_hepatobiliary_system0.87617383
82MP0001533_abnormal_skeleton_physiology0.86938344
83MP0009643_abnormal_urine_homeostasis0.86512425
84MP0009278_abnormal_bone_marrow0.84779983
85MP0009763_increased_sensitivity_to0.82698344
86MP0008007_abnormal_cellular_replicative0.82561382
87MP0003806_abnormal_nucleotide_metabolis0.81484550
88MP0001661_extended_life_span0.80793227
89MP0004147_increased_porphyrin_level0.79517644
90MP0005379_endocrine/exocrine_gland_phen0.78588348
91MP0004043_abnormal_pH_regulation0.73938948
92MP0001905_abnormal_dopamine_level0.73027445
93MP0000604_amyloidosis0.70476923
94MP0005551_abnormal_eye_electrophysiolog0.69649238
95MP0010234_abnormal_vibrissa_follicle0.69245924
96MP0003111_abnormal_nucleus_morphology0.68978653
97MP0009765_abnormal_xenobiotic_induced0.68038010
98MP0001984_abnormal_olfaction0.67535600
99MP0003045_fibrosis0.67241639
100MP0003137_abnormal_impulse_conducting0.66923312
101MP0005310_abnormal_salivary_gland0.64997484
102MP0000477_abnormal_intestine_morphology0.64873252
103MP0000609_abnormal_liver_physiology0.64270057
104MP0002095_abnormal_skin_pigmentation0.64195437
105MP0003195_calcinosis0.62597009
106MP0003880_abnormal_central_pattern0.62577171
107MP0003252_abnormal_bile_duct0.62065196
108MP0001851_eye_inflammation0.61848841
109MP0002132_abnormal_respiratory_system0.61818650
110MP0002998_abnormal_bone_remodeling0.60571956
111MP0001730_embryonic_growth_arrest0.59656665
112MP0002009_preneoplasia0.58878003
113MP0005174_abnormal_tail_pigmentation0.58559553
114MP0010307_abnormal_tumor_latency0.57585142
115MP0003690_abnormal_glial_cell0.56450678
116MP0000350_abnormal_cell_proliferation0.56251107
117MP0008873_increased_physiological_sensi0.55814292
118MP0004883_abnormal_blood_vessel0.55451846
119MP0008872_abnormal_physiological_respon0.55213048
120MP0004130_abnormal_muscle_cell0.54975264
121MP0003075_altered_response_to0.54365561
122MP0001243_abnormal_dermal_layer0.54044501
123MP0004036_abnormal_muscle_relaxation0.53506623
124MP0001958_emphysema0.53459471
125MP0005389_reproductive_system_phenotype0.53101856
126MP0000920_abnormal_myelination0.52328938
127MP0002136_abnormal_kidney_physiology0.51280241
128MP0008961_abnormal_basal_metabolism0.51258997
129MP0002822_catalepsy0.50609862
130MP0008877_abnormal_DNA_methylation0.50437228
131MP0008004_abnormal_stomach_pH0.50165324
132MP0002083_premature_death0.49052637
133MP0008058_abnormal_DNA_repair0.47563502
134MP0005408_hypopigmentation0.47106168
135MP0002693_abnormal_pancreas_physiology0.45847118
136MP0000313_abnormal_cell_death0.44635081
137MP0008770_decreased_survivor_rate0.43552943
138MP0000249_abnormal_blood_vessel0.43464006
139MP0009764_decreased_sensitivity_to0.42457633
140MP0001663_abnormal_digestive_system0.41855986
141MP0005166_decreased_susceptibility_to0.41717727
142MP0005076_abnormal_cell_differentiation0.41696121
143MP0003795_abnormal_bone_structure0.40827575
144MP0001348_abnormal_lacrimal_gland0.39383952

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)9.36721801
2Abnormality of T cell number (HP:0011839)8.93353802
3Aplastic anemia (HP:0001915)7.63745666
4Combined immunodeficiency (HP:0005387)5.92922284
5Severe combined immunodeficiency (HP:0004430)5.90773270
6Abnormality of T cells (HP:0002843)5.65735755
7Elevated erythrocyte sedimentation rate (HP:0003565)5.60985991
8Panhypogammaglobulinemia (HP:0003139)5.03851875
9Recurrent viral infections (HP:0004429)5.00093871
10Eosinophilia (HP:0001880)4.69682673
11Myositis (HP:0100614)4.53451344
12Chronic otitis media (HP:0000389)4.52781659
13Abnormality of eosinophils (HP:0001879)4.42712088
14Thyroiditis (HP:0100646)4.42451359
15Recurrent fungal infections (HP:0002841)4.14717818
16Recurrent bronchitis (HP:0002837)4.11738998
17IgG deficiency (HP:0004315)4.01201895
18Granulocytopenia (HP:0001913)3.99648298
19Joint swelling (HP:0001386)3.97316949
20Nasal polyposis (HP:0100582)3.95601206
21Abnormality of B cell number (HP:0010975)3.94718102
22B lymphocytopenia (HP:0010976)3.94718102
23Hypoplasia of the thymus (HP:0000778)3.79245729
24Leukocytosis (HP:0001974)3.69139381
25IgM deficiency (HP:0002850)3.61140367
26Autoimmune hemolytic anemia (HP:0001890)3.60053609
27Abnormal delayed hypersensitivity skin test (HP:0002963)3.41846334
28Pustule (HP:0200039)3.41275152
29Encephalitis (HP:0002383)3.33864127
30Stomatitis (HP:0010280)3.31518649
31Eczematoid dermatitis (HP:0000976)3.26999198
32Abnormality of the nasal mucosa (HP:0000433)3.26924524
33Lymphopenia (HP:0001888)3.26667990
34Meningitis (HP:0001287)3.26512325
35Oral leukoplakia (HP:0002745)3.17977429
36Abnormality of cells of the lymphoid lineage (HP:0012140)3.16998347
37Congenital stationary night blindness (HP:0007642)3.14913280
38Absent rod-and cone-mediated responses on ERG (HP:0007688)3.01886588
39Thrombocytosis (HP:0001894)2.92285825
40Keratoconjunctivitis sicca (HP:0001097)2.85621271
41Optic neuritis (HP:0100653)2.85221407
42Retrobulbar optic neuritis (HP:0100654)2.85221407
43Lymphoma (HP:0002665)2.79150721
44Abnormality of T cell physiology (HP:0011840)2.71510115
45Spontaneous hematomas (HP:0007420)2.70036960
46Orchitis (HP:0100796)2.68364188
47Abnormality of the fingertips (HP:0001211)2.68047006
48Recurrent abscess formation (HP:0002722)2.67372416
49Chronic diarrhea (HP:0002028)2.66055283
50Basal cell carcinoma (HP:0002671)2.64563192
51Increased intramyocellular lipid droplets (HP:0012240)2.64433360
52Verrucae (HP:0200043)2.62577458
53Papilloma (HP:0012740)2.62577458
54Abnormal platelet volume (HP:0011876)2.57723749
55Increased hepatocellular lipid droplets (HP:0006565)2.57674794
56Increased IgM level (HP:0003496)2.56990483
57Recurrent cutaneous fungal infections (HP:0011370)2.55805888
58Chronic mucocutaneous candidiasis (HP:0002728)2.55805888
59Keratoconjunctivitis (HP:0001096)2.55122989
60Abnormality of oral frenula (HP:0000190)2.53802980
61Mitochondrial inheritance (HP:0001427)2.50759712
62Abnormality of macrophages (HP:0004311)2.50748103
63Abnormal rod and cone electroretinograms (HP:0008323)2.50334166
64Autoimmune thrombocytopenia (HP:0001973)2.47821127
65Attenuation of retinal blood vessels (HP:0007843)2.47690491
66Mediastinal lymphadenopathy (HP:0100721)2.43129085
67Recurrent otitis media (HP:0000403)2.42799590
68Pigmentary retinal degeneration (HP:0001146)2.39014814
69Bronchitis (HP:0012387)2.37822136
70Abnormal albumin level (HP:0012116)2.36054247
71Hypoalbuminemia (HP:0003073)2.36054247
72Acute necrotizing encephalopathy (HP:0006965)2.33953039
73Gastrointestinal infarctions (HP:0005244)2.30389632
74Hypergammaglobulinemia (HP:0010702)2.30004081
75Hyperlipoproteinemia (HP:0010980)2.29851051
76Chronic sinusitis (HP:0011109)2.28857055
77Gastrointestinal inflammation (HP:0004386)2.28073139
78Increased mean platelet volume (HP:0011877)2.26196342
79Amaurosis fugax (HP:0100576)2.24518702
80Acute hepatic failure (HP:0006554)2.23929284
81Increased muscle lipid content (HP:0009058)2.23237991
82Inflammation of the large intestine (HP:0002037)2.23029693
83Hypoproteinemia (HP:0003075)2.22218275
84Pancytopenia (HP:0001876)2.19210141
85Abnormal mitochondria in muscle tissue (HP:0008316)2.17521199
86Agammaglobulinemia (HP:0004432)2.17409903
87Increased IgE level (HP:0003212)2.16516808
88Aplasia/Hypoplasia of the thymus (HP:0010515)2.16156578
89Chronic hepatic failure (HP:0100626)2.14180646
903-Methylglutaconic aciduria (HP:0003535)2.12117787
91Recurrent bacterial skin infections (HP:0005406)2.10583501
92Vasculitis (HP:0002633)2.10514475
93Chronic bronchitis (HP:0004469)2.10318134
94Prolonged bleeding time (HP:0003010)2.09321705
95Epistaxis (HP:0000421)2.08407983
96Pulmonary embolism (HP:0002204)2.08223064
97Arterial thrombosis (HP:0004420)2.07824790
98Recurrent skin infections (HP:0001581)2.07336386
99Hemoptysis (HP:0002105)2.07076747
100Tetany (HP:0001281)2.03704401
101Recurrent sinusitis (HP:0011108)2.00341659
102Type 2 muscle fiber atrophy (HP:0003554)2.00084001
103Lipid accumulation in hepatocytes (HP:0006561)1.99647725
104Papilledema (HP:0001085)1.99508956
105Bilateral sensorineural hearing impairment (HP:0008619)1.98937074
106Pulmonary infiltrates (HP:0002113)1.98851003
107Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.97003156
108Episodic fever (HP:0001954)1.96044224
109Exertional dyspnea (HP:0002875)1.95956654
110Chronic obstructive pulmonary disease (HP:0006510)1.95764302
111Obstructive lung disease (HP:0006536)1.95764302
112Petechiae (HP:0000967)1.95290179
11311 pairs of ribs (HP:0000878)1.94355025
114Trigonocephaly (HP:0000243)1.91103147
115Cellular immunodeficiency (HP:0005374)1.90075687
116Bicuspid aortic valve (HP:0001647)1.89011129
117Constricted visual fields (HP:0001133)1.88455092
118Colon cancer (HP:0003003)1.87916720
119Muscle fiber atrophy (HP:0100295)1.85599159
120Progressive macrocephaly (HP:0004481)1.85478805
121Gingival bleeding (HP:0000225)1.82885075
122Renal Fanconi syndrome (HP:0001994)1.81510371
123Increased CSF lactate (HP:0002490)1.81260967
124Multiple enchondromatosis (HP:0005701)1.79546813
125Neonatal respiratory distress (HP:0002643)1.78669977
126Gangrene (HP:0100758)1.77794342
127Decreased electroretinogram (ERG) amplitude (HP:0000654)1.77307722
128Chest pain (HP:0100749)1.74181401
129Abnormality of the thymus (HP:0000777)1.73021274
130Skin ulcer (HP:0200042)1.72007366
131Abnormality of the prostate (HP:0008775)1.71714956
132Abnormality of the pleura (HP:0002103)1.71360085
133Broad palm (HP:0001169)1.71187037
134Anhidrosis (HP:0000970)1.70199753
135Bronchiectasis (HP:0002110)1.69614960
136Hemiplegia (HP:0002301)1.67825167
137Agnosia (HP:0010524)1.67391605
138Cellulitis (HP:0100658)1.66443974
139Impaired platelet aggregation (HP:0003540)1.65308796
140Abnormal platelet function (HP:0011869)1.65308796

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK7.53232534
2MAP4K16.09413195
3MUSK3.64100828
4STK103.03460755
5ZAP703.01185823
6ITK2.99919537
7MST42.71366766
8GRK62.61530672
9EEF2K2.46748406
10JAK32.43836790
11TESK12.36137058
12MAP3K112.10574324
13CAMKK11.99222238
14TYK21.97737080
15LCK1.95753597
16PKN21.85328913
17FGFR41.84892490
18NLK1.81405683
19CSK1.79874057
20LIMK11.78127466
21JAK11.74526727
22SYK1.74310126
23MAP3K101.67265565
24TEC1.58203915
25RIPK41.55211745
26BTK1.53830416
27LRRK21.52946339
28CLK11.51444467
29TESK21.51375361
30CDK191.45398096
31IKBKE1.37844807
32EPHB11.34356698
33GRK71.30246998
34TAOK31.26521743
35FGFR31.26216884
36TSSK61.23257195
37MAP3K141.18765272
38NME21.15337977
39KIT1.14920586
40MAP3K131.14783891
41PRKCH1.14331284
42HCK1.11772447
43PRKCQ1.11232375
44KDR1.05293045
45PASK1.03529241
46CDC71.00029568
47SIK20.97620538
48MAP3K30.96537800
49FES0.94052340
50PIM10.91396668
51BLK0.90165891
52TBK10.89406511
53CDK40.87820705
54MYLK0.86877378
55EIF2AK30.85740589
56MAP3K70.85370855
57LYN0.85118817
58GRK10.82770497
59TAOK20.80281936
60CAMKK20.78973049
61PIK3CG0.78565281
62RPS6KB20.72721610
63MARK30.70710875
64FGFR10.70464385
65FLT30.69587297
66STK40.67105526
67JAK20.67101974
68FYN0.64333035
69CSF1R0.62472740
70RIPK10.61669605
71NEK60.61652520
72BMPR20.60235287
73TGFBR10.59727862
74ZAK0.58766737
75HIPK20.57880868
76TRPM70.57475669
77MAP3K80.57016695
78NEK20.55868422
79BCKDK0.54469288
80PDK10.53066783
81PDGFRB0.52837581
82TLK10.52669708
83RPS6KA40.51631779
84TRIB30.51473396
85FGR0.50347620
86PTK60.49323664
87PRPF4B0.49245772
88FGFR20.49172947
89CDK60.47105111
90IGF1R0.46693322
91EPHA30.45879044
92MELK0.45810250
93TAOK10.45515845
94ROCK10.45487391
95TGFBR20.45473803
96INSR0.44794693
97OBSCN0.44500533
98MAP2K60.44214104
99IKBKB0.43577315
100INSRR0.42910616
101TYRO30.42805585
102SIK30.42492248
103MAPK40.42443647
104ALK0.41877876
105MAP2K30.41031075
106MARK20.39468026
107BUB10.38576727
108MAPK110.35555724
109ADRBK20.34846275
110RPS6KA50.33827425
111PIM20.33313232
112IRAK40.32911637
113PAK10.32182067
114SCYL20.31899468
115PRKCA0.30990474
116TNK20.30859209
117IRAK20.29368566
118RPS6KA60.28840837
119FRK0.28787561
120MAP3K120.28642362
121MATK0.28057820
122ATR0.27975405
123ILK0.27268692
124MAPKAPK30.26423517
125CDK80.25404743
126CAMK10.25260856
127MAPK30.24425498
128AURKA0.24361828
129PRKACA0.23988323
130MAPK120.23855023
131PAK40.23781106
132CDK90.22695872
133SIK10.21986845
134ROCK20.21892326
135MAPK70.21354664
136PRKCB0.21272651
137SRC0.20997887
138RPS6KL10.20890079
139RPS6KC10.20890079
140MAPK130.19970351
141TTN0.19091024
142ERBB20.19088205
143MAPK90.18778795
144MAPK150.18481470
145UHMK10.17227240
146EGFR0.16229734
147MAPKAPK20.15819811
148ABL10.14823660

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.80603506
2Graft-versus-host disease_Homo sapiens_hsa053324.56737756
3T cell receptor signaling pathway_Homo sapiens_hsa046604.25193773
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046504.04228269
5Antigen processing and presentation_Homo sapiens_hsa046123.23601448
6Measles_Homo sapiens_hsa051622.82977738
7Hematopoietic cell lineage_Homo sapiens_hsa046402.72199413
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.38275725
9Allograft rejection_Homo sapiens_hsa053302.36778015
10Non-homologous end-joining_Homo sapiens_hsa034502.32125689
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.30353195
12Oxidative phosphorylation_Homo sapiens_hsa001902.09839458
13NF-kappa B signaling pathway_Homo sapiens_hsa040641.98753965
14DNA replication_Homo sapiens_hsa030301.82664430
15Phototransduction_Homo sapiens_hsa047441.81476218
16Ribosome_Homo sapiens_hsa030101.75675680
17Viral myocarditis_Homo sapiens_hsa054161.67939404
18Type I diabetes mellitus_Homo sapiens_hsa049401.63493592
19Leishmaniasis_Homo sapiens_hsa051401.52445743
20Jak-STAT signaling pathway_Homo sapiens_hsa046301.51531022
21Parkinsons disease_Homo sapiens_hsa050121.51459681
22Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.51188045
23Leukocyte transendothelial migration_Homo sapiens_hsa046701.51090728
24Mismatch repair_Homo sapiens_hsa034301.49633870
25Osteoclast differentiation_Homo sapiens_hsa043801.44449418
26Retinol metabolism_Homo sapiens_hsa008301.41241088
27B cell receptor signaling pathway_Homo sapiens_hsa046621.36560373
28Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.36053736
29Autoimmune thyroid disease_Homo sapiens_hsa053201.32873852
30Chemokine signaling pathway_Homo sapiens_hsa040621.25621565
31HTLV-I infection_Homo sapiens_hsa051661.25283238
32Olfactory transduction_Homo sapiens_hsa047401.23843362
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.23358462
34Herpes simplex infection_Homo sapiens_hsa051681.21804468
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.20752338
36Spliceosome_Homo sapiens_hsa030401.19366845
37Acute myeloid leukemia_Homo sapiens_hsa052211.17743665
38Colorectal cancer_Homo sapiens_hsa052101.12887682
39Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.12425657
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11195471
41Hepatitis B_Homo sapiens_hsa051611.08233608
42Toxoplasmosis_Homo sapiens_hsa051451.07280693
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.03988379
44Nitrogen metabolism_Homo sapiens_hsa009101.02379358
45Alzheimers disease_Homo sapiens_hsa050101.01114576
46Viral carcinogenesis_Homo sapiens_hsa052031.00167861
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.00158989
48Cardiac muscle contraction_Homo sapiens_hsa042600.97694953
49Shigellosis_Homo sapiens_hsa051310.95869733
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.95640811
51Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.94806612
52RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.93654276
53Morphine addiction_Homo sapiens_hsa050320.92839881
54Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.92272300
55Apoptosis_Homo sapiens_hsa042100.91884233
56NOD-like receptor signaling pathway_Homo sapiens_hsa046210.91772696
57Protein export_Homo sapiens_hsa030600.87702728
58Base excision repair_Homo sapiens_hsa034100.86710734
59Systemic lupus erythematosus_Homo sapiens_hsa053220.85788378
60Epstein-Barr virus infection_Homo sapiens_hsa051690.84674864
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84138128
62Influenza A_Homo sapiens_hsa051640.83580111
63Taste transduction_Homo sapiens_hsa047420.82196721
64Pancreatic cancer_Homo sapiens_hsa052120.81118953
65Platelet activation_Homo sapiens_hsa046110.80334116
66Legionellosis_Homo sapiens_hsa051340.77840421
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.75390722
68Chronic myeloid leukemia_Homo sapiens_hsa052200.75293402
69Pentose phosphate pathway_Homo sapiens_hsa000300.71376827
70Asthma_Homo sapiens_hsa053100.69498013
71Collecting duct acid secretion_Homo sapiens_hsa049660.68721059
72Linoleic acid metabolism_Homo sapiens_hsa005910.67845889
73Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.67656389
74TNF signaling pathway_Homo sapiens_hsa046680.65736393
75VEGF signaling pathway_Homo sapiens_hsa043700.63418946
76Peroxisome_Homo sapiens_hsa041460.62356334
77Salmonella infection_Homo sapiens_hsa051320.60294376
78Non-small cell lung cancer_Homo sapiens_hsa052230.59559288
79Staphylococcus aureus infection_Homo sapiens_hsa051500.59554995
80Cell cycle_Homo sapiens_hsa041100.57834925
81RNA polymerase_Homo sapiens_hsa030200.57766100
82Nucleotide excision repair_Homo sapiens_hsa034200.57051789
83Proteasome_Homo sapiens_hsa030500.56845029
84Huntingtons disease_Homo sapiens_hsa050160.56388206
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54126445
86AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.53993126
87GABAergic synapse_Homo sapiens_hsa047270.52414472
88Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51686106
89Toll-like receptor signaling pathway_Homo sapiens_hsa046200.49284119
90Hepatitis C_Homo sapiens_hsa051600.49149209
91RNA transport_Homo sapiens_hsa030130.46607060
92Endocytosis_Homo sapiens_hsa041440.46323867
93Tuberculosis_Homo sapiens_hsa051520.45389893
94Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45310301
95RNA degradation_Homo sapiens_hsa030180.43792638
96Homologous recombination_Homo sapiens_hsa034400.43617483
97Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42926501
98Chemical carcinogenesis_Homo sapiens_hsa052040.42922118
99Malaria_Homo sapiens_hsa051440.41959441
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.41680646
101Thyroid cancer_Homo sapiens_hsa052160.40599780
102Ras signaling pathway_Homo sapiens_hsa040140.38377678
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38282960
104Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38123549
105Pertussis_Homo sapiens_hsa051330.37856008
106One carbon pool by folate_Homo sapiens_hsa006700.37139563
107Renin secretion_Homo sapiens_hsa049240.36754835
108mRNA surveillance pathway_Homo sapiens_hsa030150.36658727
109Notch signaling pathway_Homo sapiens_hsa043300.36481866
110p53 signaling pathway_Homo sapiens_hsa041150.36465578
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35762106
112Small cell lung cancer_Homo sapiens_hsa052220.35551217
113Rheumatoid arthritis_Homo sapiens_hsa053230.34835538
114Mineral absorption_Homo sapiens_hsa049780.33106239
115Neurotrophin signaling pathway_Homo sapiens_hsa047220.32745947
116Circadian entrainment_Homo sapiens_hsa047130.29517134
117Cholinergic synapse_Homo sapiens_hsa047250.29038252
118ABC transporters_Homo sapiens_hsa020100.28909565
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.27843208
120Cyanoamino acid metabolism_Homo sapiens_hsa004600.27583876
121Regulation of autophagy_Homo sapiens_hsa041400.27537235
122MicroRNAs in cancer_Homo sapiens_hsa052060.27447995
123Endometrial cancer_Homo sapiens_hsa052130.26802162
124Phagosome_Homo sapiens_hsa041450.25810527
125Ether lipid metabolism_Homo sapiens_hsa005650.25295898
126Drug metabolism - other enzymes_Homo sapiens_hsa009830.25263592
127Prostate cancer_Homo sapiens_hsa052150.24802732
128Rap1 signaling pathway_Homo sapiens_hsa040150.24652989
129Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.24320294
130Maturity onset diabetes of the young_Homo sapiens_hsa049500.23222709
131FoxO signaling pathway_Homo sapiens_hsa040680.22573839
132Glutamatergic synapse_Homo sapiens_hsa047240.22406421
133SNARE interactions in vesicular transport_Homo sapiens_hsa041300.21799541
134HIF-1 signaling pathway_Homo sapiens_hsa040660.21461984
135Prolactin signaling pathway_Homo sapiens_hsa049170.21127317
136mTOR signaling pathway_Homo sapiens_hsa041500.21116747
137Insulin resistance_Homo sapiens_hsa049310.20691675
138Calcium signaling pathway_Homo sapiens_hsa040200.20254235
139Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20061695
140Phosphatidylinositol signaling system_Homo sapiens_hsa040700.16457246
141Caffeine metabolism_Homo sapiens_hsa002320.15721430
142Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.13482843
143Pyrimidine metabolism_Homo sapiens_hsa002400.12817009
144Sphingolipid signaling pathway_Homo sapiens_hsa040710.11786313
145Carbohydrate digestion and absorption_Homo sapiens_hsa049730.10591675

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