TRBJ1-5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450919.33951049
2pyrimidine ribonucleoside catabolic process (GO:0046133)9.32321548
3DNA deamination (GO:0045006)8.84516063
4negative T cell selection (GO:0043383)8.26364284
5positive regulation of gamma-delta T cell activation (GO:0046645)8.21904938
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.81006997
7negative regulation of cell killing (GO:0031342)7.81006997
8negative thymic T cell selection (GO:0045060)7.69531787
9regulation of isotype switching to IgG isotypes (GO:0048302)7.36733124
10positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.73036185
11response to interleukin-15 (GO:0070672)6.71049782
12regulation of gamma-delta T cell differentiation (GO:0045586)6.68349379
13positive T cell selection (GO:0043368)6.50101178
14regulation of T cell tolerance induction (GO:0002664)6.35282471
15thymic T cell selection (GO:0045061)6.34870035
16positive thymic T cell selection (GO:0045059)6.33259787
17interferon-gamma production (GO:0032609)6.20111869
18T cell selection (GO:0045058)6.12729421
19positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.10232832
20regulation of gamma-delta T cell activation (GO:0046643)5.97510411
21antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.96070110
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.96070110
23negative regulation by host of viral transcription (GO:0043922)5.92915314
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.92511334
25cellular response to interleukin-15 (GO:0071350)5.80628715
26eosinophil chemotaxis (GO:0048245)5.71297559
27T cell receptor signaling pathway (GO:0050852)5.52347051
28regulation of activation of Janus kinase activity (GO:0010533)5.51467020
29negative regulation of T cell apoptotic process (GO:0070233)5.51064190
30T cell costimulation (GO:0031295)5.39067486
31positive regulation of tolerance induction (GO:0002645)5.31235118
32lymphocyte costimulation (GO:0031294)5.29041757
33positive regulation of interleukin-8 secretion (GO:2000484)5.19970979
34activated T cell proliferation (GO:0050798)5.19301717
35eosinophil migration (GO:0072677)5.16498880
36Arp2/3 complex-mediated actin nucleation (GO:0034314)5.13127642
37macrophage chemotaxis (GO:0048246)5.12234361
38leukocyte aggregation (GO:0070486)5.12159116
39regulation of lymphocyte chemotaxis (GO:1901623)5.09787787
40T cell migration (GO:0072678)5.05264774
41regulation of chronic inflammatory response (GO:0002676)5.00974697
42antigen processing and presentation of endogenous antigen (GO:0019883)4.99535363
43regulation of alpha-beta T cell proliferation (GO:0046640)4.82413316
44positive regulation of T cell chemotaxis (GO:0010820)4.81317812
45regulation of T cell chemotaxis (GO:0010819)4.81317812
46pyrimidine nucleoside catabolic process (GO:0046135)4.73357233
47positive regulation of isotype switching (GO:0045830)4.72428521
48negative regulation of T cell mediated immunity (GO:0002710)4.69979817
49positive regulation of alpha-beta T cell proliferation (GO:0046641)4.65772903
50regulation of tolerance induction (GO:0002643)4.63471325
51antigen receptor-mediated signaling pathway (GO:0050851)4.60778080
52positive regulation of immunoglobulin mediated immune response (GO:0002891)4.58289925
53positive regulation of B cell mediated immunity (GO:0002714)4.58289925
54negative regulation of viral genome replication (GO:0045071)4.56062033
55regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.54016262
56positive regulation of calcium-mediated signaling (GO:0050850)4.53593154
57regulation of T cell receptor signaling pathway (GO:0050856)4.52380199
58actin nucleation (GO:0045010)4.49567551
59positive regulation of monocyte chemotaxis (GO:0090026)4.38231892
60regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.36408737
61regulation of natural killer cell mediated immunity (GO:0002715)4.35505743
62regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.35505743
63regulation of interleukin-2 biosynthetic process (GO:0045076)4.22703519
64positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.21616769
65positive regulation of natural killer cell mediated immunity (GO:0002717)4.21616769
66positive regulation of interleukin-2 production (GO:0032743)4.15409232
67monocyte chemotaxis (GO:0002548)4.14371431
68regulation of regulatory T cell differentiation (GO:0045589)4.11953787
69regulation of mononuclear cell migration (GO:0071675)4.11883999
70regulation of isotype switching (GO:0045191)4.11486861
71positive regulation of lymphocyte migration (GO:2000403)4.07292506
72regulation of immunoglobulin mediated immune response (GO:0002889)4.05316252
73regulation of B cell receptor signaling pathway (GO:0050855)4.04860919
74positive regulation of DNA recombination (GO:0045911)4.03042717
75positive regulation of T cell apoptotic process (GO:0070234)4.02503548
76mast cell activation (GO:0045576)3.99896336
77positive regulation of humoral immune response (GO:0002922)3.97958100
78positive regulation of B cell differentiation (GO:0045579)3.96802494
79regulation of macrophage chemotaxis (GO:0010758)3.94181559
80regulation of B cell mediated immunity (GO:0002712)3.93986713
81positive regulation of immunoglobulin production (GO:0002639)3.92039515
82regulation of chemokine-mediated signaling pathway (GO:0070099)3.91699119
83dendritic cell chemotaxis (GO:0002407)3.91117619
84cytolysis (GO:0019835)3.87094040
85T cell differentiation (GO:0030217)3.86167210
86alpha-beta T cell activation (GO:0046631)3.80408967
87regulation of interleukin-8 secretion (GO:2000482)3.79205128
88regulation of T cell apoptotic process (GO:0070232)3.76328611
89negative regulation of lymphocyte apoptotic process (GO:0070229)3.75908241
90regulation of response to interferon-gamma (GO:0060330)3.74678568
91positive regulation of T cell mediated cytotoxicity (GO:0001916)3.72155135
92positive regulation of interleukin-4 production (GO:0032753)3.71645555
93positive regulation of translational initiation (GO:0045948)3.71466400
94regulation of leukocyte mediated cytotoxicity (GO:0001910)3.71368661
95positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.69971952
96negative regulation of lymphocyte mediated immunity (GO:0002707)3.68887116
97positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.63789157
98positive regulation of T cell cytokine production (GO:0002726)3.63702040
99regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.63665511
100regulation of immunoglobulin production (GO:0002637)3.63158551
101alpha-beta T cell differentiation (GO:0046632)3.61545603
102V(D)J recombination (GO:0033151)3.59277503
103negative regulation of calcium ion transport into cytosol (GO:0010523)3.56572574
104regulation of T cell mediated cytotoxicity (GO:0001914)3.55551458
105positive regulation of immune response to tumor cell (GO:0002839)3.55278740
106regulation of immune response to tumor cell (GO:0002837)3.55278740
107regulation of response to tumor cell (GO:0002834)3.55278740
108positive regulation of response to tumor cell (GO:0002836)3.55278740
109T cell activation (GO:0042110)3.53589573
110sequestering of actin monomers (GO:0042989)3.53282858
111negative regulation of T cell receptor signaling pathway (GO:0050860)3.47031695
112lymphocyte migration (GO:0072676)3.46678038
113T cell proliferation (GO:0042098)3.44807808
114regulation of cell killing (GO:0031341)3.44692056
115regulation of interleukin-12 biosynthetic process (GO:0045075)3.44426956
116cellular response to interleukin-4 (GO:0071353)3.44060715
117negative regulation of B cell proliferation (GO:0030889)3.41153507
118natural killer cell activation (GO:0030101)3.39948834
119positive regulation of cell killing (GO:0031343)3.36644438
120regulation of lymphocyte migration (GO:2000401)3.33017215
121T cell homeostasis (GO:0043029)3.31380466
122negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.30151508
123dendritic cell migration (GO:0036336)3.29158086
124positive regulation of interleukin-1 beta secretion (GO:0050718)3.29058071
125regulation of oxidative stress-induced neuron death (GO:1903203)3.29025788
126regulation of calcium-mediated signaling (GO:0050848)3.28046243
127modulation by host of viral transcription (GO:0043921)3.24321082
128modulation by host of symbiont transcription (GO:0052472)3.24321082
129positive regulation of T cell migration (GO:2000406)3.23529122
130angiogenesis involved in wound healing (GO:0060055)3.22537981
131regulation of viral genome replication (GO:0045069)3.22413480
132regulation of interleukin-2 production (GO:0032663)3.22284078
133immune response-activating cell surface receptor signaling pathway (GO:0002429)3.21893875
134positive regulation of lymphocyte mediated immunity (GO:0002708)3.19271601
135negative regulation of stress fiber assembly (GO:0051497)3.19039152
136response to interleukin-4 (GO:0070670)3.15739987
137modulation of transcription in other organism involved in symbiotic interaction (GO:0052312)3.13585587
138antigen processing and presentation via MHC class Ib (GO:0002475)3.12726565
139regulation of B cell differentiation (GO:0045577)3.12499792
140mast cell activation involved in immune response (GO:0002279)3.12411129
141mast cell degranulation (GO:0043303)3.12411129
142regulation of interleukin-1 beta secretion (GO:0050706)3.12062321
143regulation of lymphocyte mediated immunity (GO:0002706)3.10754582
144positive regulation of interleukin-1 secretion (GO:0050716)3.10728412
145negative regulation of viral transcription (GO:0032897)3.10296848
146regulation of defense response to virus by virus (GO:0050690)3.10086223
147positive regulation of T cell activation (GO:0050870)3.09966666
148natural killer cell differentiation (GO:0001779)3.07739948
149leukocyte cell-cell adhesion (GO:0007159)3.03366579
150signal complex assembly (GO:0007172)3.02503147
151ribosomal small subunit assembly (GO:0000028)3.01762213
152regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.00458122
153heterotypic cell-cell adhesion (GO:0034113)2.99314320
154myeloid dendritic cell activation (GO:0001773)2.98682832
155cytidine deamination (GO:0009972)10.4456223
156cytidine metabolic process (GO:0046087)10.4456223
157cytidine catabolic process (GO:0006216)10.4456223

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.25150707
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.52722871
3RUNX_20019798_ChIP-Seq_JUKART_Human4.42190037
4E2F7_22180533_ChIP-Seq_HELA_Human4.19834796
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.88827092
6FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.70188043
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.65348769
8MYB_26560356_Chip-Seq_TH2_Human3.46452641
9EGR1_19374776_ChIP-ChIP_THP-1_Human3.40323997
10STAT4_19710469_ChIP-ChIP_TH1__Mouse3.28641593
11MYC_22102868_ChIP-Seq_BL_Human3.27651413
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.22976887
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.18017130
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.09869299
15MAF_26560356_Chip-Seq_TH1_Human3.06336298
16IRF8_22096565_ChIP-ChIP_GC-B_Human3.03139466
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.75703361
18UTX_26944678_Chip-Seq_JUKART_Human2.72079521
19MYB_26560356_Chip-Seq_TH1_Human2.70086131
20IRF8_21731497_ChIP-ChIP_J774_Mouse2.53951380
21GATA3_27048872_Chip-Seq_THYMUS_Human2.33252932
22RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.24832457
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.24041536
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.21869185
25KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.18138707
26SMAD_19615063_ChIP-ChIP_OVARY_Human2.17644693
27CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.16275270
28BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.14468601
29E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04242897
30MAF_26560356_Chip-Seq_TH2_Human2.03048100
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.02473014
32VDR_21846776_ChIP-Seq_THP-1_Human1.98960083
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.95879047
34SCL_19346495_ChIP-Seq_HPC-7_Human1.88458252
35NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.87877005
36RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.87461871
37IRF8_27001747_Chip-Seq_BMDM_Mouse1.84799045
38SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.82464896
39BP1_19119308_ChIP-ChIP_Hs578T_Human1.81964055
40SPI1_23547873_ChIP-Seq_NB4_Human1.80931142
41TCF7_22412390_ChIP-Seq_EML_Mouse1.78643195
42NOTCH1_21737748_ChIP-Seq_TLL_Human1.77874908
43VDR_22108803_ChIP-Seq_LS180_Human1.76727813
44MYB_21317192_ChIP-Seq_ERMYB_Mouse1.76452602
45E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.76009703
46KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.71249621
47KDM2B_26808549_Chip-Seq_DND41_Human1.66141092
48SPI1_23127762_ChIP-Seq_K562_Human1.64831218
49FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.55169263
50CIITA_25753668_ChIP-Seq_RAJI_Human1.52820406
51STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.50921135
52VDR_24763502_ChIP-Seq_THP-1_Human1.49900729
53VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.49683336
54ELF1_17652178_ChIP-ChIP_JURKAT_Human1.43293279
55TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.43231250
56ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.34937651
57BRD4_27068464_Chip-Seq_AML-cells_Mouse1.34096820
58GATA3_26560356_Chip-Seq_TH2_Human1.28940901
59EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.28658673
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28421751
61KDM2B_26808549_Chip-Seq_JURKAT_Human1.27316198
62PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26751743
63HTT_18923047_ChIP-ChIP_STHdh_Human1.25394879
64RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.21552314
65PU_27001747_Chip-Seq_BMDM_Mouse1.20217477
66MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.19403107
67TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19244424
68PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.18500138
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.17664518
70GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16721455
71FOXM1_23109430_ChIP-Seq_U2OS_Human1.16452944
72BCL6_27268052_Chip-Seq_Bcells_Human1.16392113
73RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.14314097
74KDM2B_26808549_Chip-Seq_SUP-B15_Human1.10794394
75NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.09681151
76VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.07359542
77EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.05451757
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.00896493
79TAF2_19829295_ChIP-Seq_ESCs_Human1.00611312
80VDR_23849224_ChIP-Seq_CD4+_Human0.99899697
81E2F4_17652178_ChIP-ChIP_JURKAT_Human0.99447758
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98958061
83FOXP3_21729870_ChIP-Seq_TREG_Human0.98604312
84GATA1_19941827_ChIP-Seq_MEL_Mouse0.97829133
85P300_27268052_Chip-Seq_Bcells_Human0.96927848
86CTCF_20526341_ChIP-Seq_ESCs_Human0.95216282
87LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.95157803
88GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.94934919
89HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94697646
90BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.93677793
91ELF1_20517297_ChIP-Seq_JURKAT_Human0.93610856
92TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.91801362
93PU.1_20513432_ChIP-Seq_Bcells_Mouse0.91721512
94CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91114652
95SA1_27219007_Chip-Seq_Bcells_Human0.90847920
96YY1_22570637_ChIP-Seq_MALME-3M_Human0.89914571
97CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89747849
98BCOR_27268052_Chip-Seq_Bcells_Human0.89643250
99NANOG_20526341_ChIP-Seq_ESCs_Human0.88645362
100STAT6_21828071_ChIP-Seq_BEAS2B_Human0.88509561
101ELK1_19687146_ChIP-ChIP_HELA_Human0.88459403
102GATA3_26560356_Chip-Seq_TH1_Human0.88269667
103CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87843415
104GATA1_22383799_ChIP-Seq_G1ME_Mouse0.87134703
105ELK3_25401928_ChIP-Seq_HUVEC_Human0.85898439
106PCGF2_27294783_Chip-Seq_NPCs_Mouse0.85118483
107GATA6_21074721_ChIP-Seq_CACO-2_Human0.84290017
108BCAT_22108803_ChIP-Seq_LS180_Human0.84274788
109PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.83751328
110HOXB4_20404135_ChIP-ChIP_EML_Mouse0.82822191
111E2F1_20622854_ChIP-Seq_HELA_Human0.82195047
112EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.81481154
113RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81467514
114CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.80937077
115GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.80186776
116TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80016116
117POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.76972379
118RXR_22108803_ChIP-Seq_LS180_Human0.76151874
119CTBP1_25329375_ChIP-Seq_LNCAP_Human0.75546451
120RBPJ_21746931_ChIP-Seq_IB4_Human0.74985254
121EZH2_22144423_ChIP-Seq_EOC_Human0.74902422
122FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74504916
123SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.73689454
124CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.73134074
125FOXH1_21741376_ChIP-Seq_EPCs_Human0.72453945
126P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.71724492
127GATA2_19941826_ChIP-Seq_K562_Human0.71296111
128GATA1_19941826_ChIP-Seq_K562_Human0.70491552
129GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.69892908
130GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.69469378
131CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.69265302
132TP53_22573176_ChIP-Seq_HFKS_Human0.69105717
133AR_20517297_ChIP-Seq_VCAP_Human0.68136852
134FOXH1_21741376_ChIP-Seq_ESCs_Human0.66844201
135LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.66828483
136VDR_24787735_ChIP-Seq_THP-1_Human0.66651036
137GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.66625378
138NCOR1_26117541_ChIP-Seq_K562_Human0.64893970
139KDM5A_27292631_Chip-Seq_BREAST_Human0.63608635
140PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.62914739
141SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.62238605
142XRN2_22483619_ChIP-Seq_HELA_Human0.61618140
143RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.60125312
144ELF5_23300383_ChIP-Seq_T47D_Human0.58690849
145SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.58530507

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology5.55043813
2MP0005671_abnormal_response_to4.74877423
3MP0001835_abnormal_antigen_presentation3.87327212
4MP0000685_abnormal_immune_system3.84956090
5MP0001800_abnormal_humoral_immune3.56521664
6MP0002398_abnormal_bone_marrow3.12263777
7MP0000703_abnormal_thymus_morphology3.07867583
8MP0002420_abnormal_adaptive_immunity3.01663561
9MP0001819_abnormal_immune_cell2.97068381
10MP0009333_abnormal_splenocyte_physiolog2.96869156
11MP0002723_abnormal_immune_serum2.89679840
12MP0001790_abnormal_immune_system2.80710721
13MP0005387_immune_system_phenotype2.80710721
14MP0005000_abnormal_immune_tolerance2.79778966
15MP0002396_abnormal_hematopoietic_system2.75974306
16MP0002452_abnormal_antigen_presenting2.72195914
17MP0000716_abnormal_immune_system2.64815791
18MP0003300_gastrointestinal_ulcer2.64087992
19MP0002405_respiratory_system_inflammati2.54259402
20MP0002166_altered_tumor_susceptibility2.53593609
21MP0002722_abnormal_immune_system2.53080927
22MP0005025_abnormal_response_to2.42364814
23MP0000689_abnormal_spleen_morphology2.35682633
24MP0006082_CNS_inflammation2.30989550
25MP0003436_decreased_susceptibility_to2.28440594
26MP0010155_abnormal_intestine_physiology2.27789105
27MP0002429_abnormal_blood_cell2.19075785
28MP0003724_increased_susceptibility_to2.17558889
29MP0009785_altered_susceptibility_to2.16607263
30MP0004947_skin_inflammation2.07956645
31MP0002006_tumorigenesis2.05449859
32MP0002148_abnormal_hypersensitivity_rea2.05103417
33MP0001873_stomach_inflammation1.92633877
34MP0003866_abnormal_defecation1.88079461
35MP0002419_abnormal_innate_immunity1.86281944
36MP0005464_abnormal_platelet_physiology1.82699354
37MP0002163_abnormal_gland_morphology1.70114970
38MP0001845_abnormal_inflammatory_respons1.68276460
39MP0000858_altered_metastatic_potential1.65985347
40MP0002277_abnormal_respiratory_mucosa1.63046191
41MP0004808_abnormal_hematopoietic_stem1.55884649
42MP0004381_abnormal_hair_follicle1.55138536
43MP0003878_abnormal_ear_physiology1.48850482
44MP0005377_hearing/vestibular/ear_phenot1.48850482
45MP0002933_joint_inflammation1.47228140
46MP0000465_gastrointestinal_hemorrhage1.42999868
47MP0003786_premature_aging1.42494309
48MP0001853_heart_inflammation1.35995879
49MP0002132_abnormal_respiratory_system1.33146099
50MP0002877_abnormal_melanocyte_morpholog1.30735117
51MP0003303_peritoneal_inflammation1.30207705
52MP0002138_abnormal_hepatobiliary_system1.28741219
53MP0001919_abnormal_reproductive_system1.27854994
54MP0003448_altered_tumor_morphology1.25792733
55MP0008961_abnormal_basal_metabolism1.23004176
56MP0009379_abnormal_foot_pigmentation1.20864958
57MP0002009_preneoplasia1.14838372
58MP0001188_hyperpigmentation1.09586182
59MP0005645_abnormal_hypothalamus_physiol1.09028257
60MP0002019_abnormal_tumor_incidence1.08733686
61MP0005075_abnormal_melanosome_morpholog1.06871690
62MP0003045_fibrosis1.05585207
63MP0000490_abnormal_crypts_of1.05584402
64MP0002876_abnormal_thyroid_physiology1.05339240
65MP0001851_eye_inflammation1.05289341
66MP0005257_abnormal_intraocular_pressure1.03949540
67MP0002693_abnormal_pancreas_physiology1.03056531
68MP0004185_abnormal_adipocyte_glucose1.01633416
69MP0010352_gastrointestinal_tract_polyps1.00679117
70MP0001533_abnormal_skeleton_physiology0.99039131
71MP0008872_abnormal_physiological_respon0.98791863
72MP0010307_abnormal_tumor_latency0.98141303
73MP0008469_abnormal_protein_level0.96869010
74MP0001905_abnormal_dopamine_level0.94902029
75MP0003137_abnormal_impulse_conducting0.92656096
76MP0004134_abnormal_chest_morphology0.89885432
77MP0005076_abnormal_cell_differentiation0.88798313
78MP0004145_abnormal_muscle_electrophysio0.88291577
79MP0005379_endocrine/exocrine_gland_phen0.86669494
80MP0005310_abnormal_salivary_gland0.83724096
81MP0004510_myositis0.82412761
82MP0005023_abnormal_wound_healing0.81637281
83MP0000604_amyloidosis0.80911673
84MP0006054_spinal_hemorrhage0.80585160
85MP0008057_abnormal_DNA_replication0.80581115
86MP0001663_abnormal_digestive_system0.80075556
87MP0009765_abnormal_xenobiotic_induced0.79227516
88MP0005397_hematopoietic_system_phenotyp0.77839496
89MP0001545_abnormal_hematopoietic_system0.77839496
90MP0010094_abnormal_chromosome_stability0.76546643
91MP0000372_irregular_coat_pigmentation0.73885930
92MP0003077_abnormal_cell_cycle0.73640991
93MP0003075_altered_response_to0.73268654
94MP0001485_abnormal_pinna_reflex0.71406358
95MP0001958_emphysema0.68803725
96MP0001765_abnormal_ion_homeostasis0.67964491
97MP0002909_abnormal_adrenal_gland0.66663426
98MP0005166_decreased_susceptibility_to0.66344372
99MP0001348_abnormal_lacrimal_gland0.64662104
100MP0003567_abnormal_fetal_cardiomyocyte0.63345343
101MP0003011_delayed_dark_adaptation0.63184448
102MP0000609_abnormal_liver_physiology0.62416120
103MP0005389_reproductive_system_phenotype0.60624719
104MP0002998_abnormal_bone_remodeling0.60350540
105MP0001501_abnormal_sleep_pattern0.58685355
106MP0009763_increased_sensitivity_to0.58477610
107MP0001542_abnormal_bone_strength0.58450211
108MP0002095_abnormal_skin_pigmentation0.57263567
109MP0005636_abnormal_mineral_homeostasis0.57110928
110MP0006035_abnormal_mitochondrial_morpho0.56809048
111MP0009764_decreased_sensitivity_to0.56383346
112MP0004957_abnormal_blastocyst_morpholog0.56162339
113MP0004130_abnormal_muscle_cell0.55560475
114MP0003806_abnormal_nucleotide_metabolis0.55339908
115MP0009643_abnormal_urine_homeostasis0.54741807
116MP0008007_abnormal_cellular_replicative0.53059395
117MP0005360_urolithiasis0.52451367
118MP0005551_abnormal_eye_electrophysiolog0.51713550
119MP0005330_cardiomyopathy0.51576045
120MP0006036_abnormal_mitochondrial_physio0.51323142
121MP0008873_increased_physiological_sensi0.50805739
122MP0000477_abnormal_intestine_morphology0.48557913
123MP0003111_abnormal_nucleus_morphology0.47761810
124MP0003795_abnormal_bone_structure0.47265211
125MP0000350_abnormal_cell_proliferation0.46688377
126MP0002136_abnormal_kidney_physiology0.45727392
127MP0001661_extended_life_span0.44304099
128MP0005670_abnormal_white_adipose0.43744571
129MP0003693_abnormal_embryo_hatching0.42822443
130MP0000249_abnormal_blood_vessel0.42083641
131MP0003453_abnormal_keratinocyte_physiol0.42073872
132MP0005666_abnormal_adipose_tissue0.41842655
133MP0003279_aneurysm0.41298875
134MP0000920_abnormal_myelination0.41147955
135MP0003943_abnormal_hepatobiliary_system0.40924521
136MP0004233_abnormal_muscle_weight0.40564237
137MP0000627_abnormal_mammary_gland0.39606363
138MP0000013_abnormal_adipose_tissue0.39559334
139MP0003656_abnormal_erythrocyte_physiolo0.39055919
140MP0002083_premature_death0.38543463
141MP0002970_abnormal_white_adipose0.37614364
142MP0003091_abnormal_cell_migration0.37287270
143MP0005174_abnormal_tail_pigmentation0.36605671

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)8.74013711
2Abnormality of T cell number (HP:0011839)8.36020586
3Elevated erythrocyte sedimentation rate (HP:0003565)5.78283769
4Abnormality of T cells (HP:0002843)5.58267503
5Severe combined immunodeficiency (HP:0004430)5.28780838
6Combined immunodeficiency (HP:0005387)5.28542097
7Recurrent viral infections (HP:0004429)5.07883817
8Hypoproteinemia (HP:0003075)4.94012068
9Nasal polyposis (HP:0100582)4.76168695
10Panhypogammaglobulinemia (HP:0003139)4.60174711
11Autoimmune hemolytic anemia (HP:0001890)4.43191470
12Recurrent fungal infections (HP:0002841)4.30697785
13Recurrent bronchitis (HP:0002837)4.29862581
14IgG deficiency (HP:0004315)4.24082510
15Stomatitis (HP:0010280)4.20396156
16Aplastic anemia (HP:0001915)4.20385775
17Eosinophilia (HP:0001880)4.19189871
18Abnormality of eosinophils (HP:0001879)4.18808204
19Chronic otitis media (HP:0000389)4.05120044
20Abnormality of the nasal mucosa (HP:0000433)3.93602958
21Stomach cancer (HP:0012126)3.92231250
22Myositis (HP:0100614)3.79390767
23IgM deficiency (HP:0002850)3.76290326
24Thyroiditis (HP:0100646)3.74164585
25Abnormality of macrophages (HP:0004311)3.63882072
26Abnormal delayed hypersensitivity skin test (HP:0002963)3.58987186
27B lymphocytopenia (HP:0010976)3.58540185
28Abnormality of B cell number (HP:0010975)3.58540185
29Leukocytosis (HP:0001974)3.56295761
30Pustule (HP:0200039)3.54553299
31Granulocytopenia (HP:0001913)3.51117735
32Chronic mucocutaneous candidiasis (HP:0002728)3.44434092
33Recurrent cutaneous fungal infections (HP:0011370)3.44434092
34Chronic diarrhea (HP:0002028)3.37917912
35Abnormality of the prostate (HP:0008775)3.34279810
36Joint swelling (HP:0001386)3.30508016
37Hemiplegia (HP:0002301)3.12567682
38Eczematoid dermatitis (HP:0000976)3.09896229
39Lymphopenia (HP:0001888)3.09798920
40Agammaglobulinemia (HP:0004432)3.03260191
41Volvulus (HP:0002580)2.99304585
42Hypoplasia of the thymus (HP:0000778)2.98395275
43Abnormality of cells of the lymphoid lineage (HP:0012140)2.98102578
44Gangrene (HP:0100758)2.91848577
45Abnormality of T cell physiology (HP:0011840)2.91107820
46Abnormality of the fingertips (HP:0001211)2.89785591
47Hypoalbuminemia (HP:0003073)2.88594711
48Abnormal albumin level (HP:0012116)2.88594711
49Thrombocytosis (HP:0001894)2.87923772
50Alveolar cell carcinoma (HP:0006519)2.87241673
51Toxemia of pregnancy (HP:0100603)2.84313027
52Meningitis (HP:0001287)2.83534552
53Verrucae (HP:0200043)2.76566654
54Papilloma (HP:0012740)2.76566654
55Increased IgM level (HP:0003496)2.75655750
56Keratoconjunctivitis (HP:0001096)2.74597723
57Ureteral stenosis (HP:0000071)2.73224386
58Neoplasm of the tracheobronchial system (HP:0100552)2.69241972
59Encephalitis (HP:0002383)2.66039815
603-Methylglutaconic aciduria (HP:0003535)2.64710840
61Abnormality of the pleura (HP:0002103)2.63521741
62Autoimmune thrombocytopenia (HP:0001973)2.63260170
63Colon cancer (HP:0003003)2.59275378
64Inflammation of the large intestine (HP:0002037)2.54173646
65Recurrent abscess formation (HP:0002722)2.51055408
66Lymphoma (HP:0002665)2.50583307
67Basal cell carcinoma (HP:0002671)2.50570523
68Pulmonary embolism (HP:0002204)2.50103367
69Mediastinal lymphadenopathy (HP:0100721)2.50002875
70Recurrent sinusitis (HP:0011108)2.49367993
71Ureteral obstruction (HP:0006000)2.47324810
72Gastrointestinal inflammation (HP:0004386)2.46514489
73Spontaneous hematomas (HP:0007420)2.44933499
74Bronchitis (HP:0012387)2.43398298
75Easy fatigability (HP:0003388)2.42916533
76Congenital stationary night blindness (HP:0007642)2.42624361
77Recurrent skin infections (HP:0001581)2.38031921
78Amyotrophic lateral sclerosis (HP:0007354)2.37801261
79Hypochromic anemia (HP:0001931)2.32385492
80Attenuation of retinal blood vessels (HP:0007843)2.28444282
81Absent rod-and cone-mediated responses on ERG (HP:0007688)2.26300145
82Gastrointestinal infarctions (HP:0005244)2.21322805
83Tetraplegia (HP:0002445)2.20361723
84Decreased activity of mitochondrial respiratory chain (HP:0008972)2.17788236
85Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.17788236
86Decreased electroretinogram (ERG) amplitude (HP:0000654)2.17673368
87Recurrent otitis media (HP:0000403)2.17345792
88IgA deficiency (HP:0002720)2.15395909
89Mitochondrial inheritance (HP:0001427)2.14736321
90Cutis marmorata (HP:0000965)2.13797930
91Disinhibition (HP:0000734)2.13508023
92Hypergammaglobulinemia (HP:0010702)2.13242770
93Severe visual impairment (HP:0001141)2.13200965
94Colitis (HP:0002583)2.09717695
95Vasculitis (HP:0002633)2.04776599
96Abnormality of the pericardium (HP:0001697)2.03101412
97Keratitis (HP:0000491)2.02741863
98Recurrent bacterial skin infections (HP:0005406)2.02703675
99Striae distensae (HP:0001065)2.02036176
100Pulmonary infiltrates (HP:0002113)2.00181829
101Abnormality of oral frenula (HP:0000190)2.00144947
102Epistaxis (HP:0000421)1.99448387
103Increased IgE level (HP:0003212)1.99368217
104Abnormality of male internal genitalia (HP:0000022)1.98295797
105Chronic sinusitis (HP:0011109)1.96637720
106Renal cortical cysts (HP:0000803)1.95800610
107Hepatocellular necrosis (HP:0001404)1.95711476
108Abnormal platelet volume (HP:0011876)1.94015556
109Abnormality of the alveolar ridges (HP:0006477)1.93448321
110Acute hepatic failure (HP:0006554)1.92020719
111Optic neuritis (HP:0100653)1.89856229
112Retrobulbar optic neuritis (HP:0100654)1.89856229
113Bicuspid aortic valve (HP:0001647)1.89541775
114Obstructive lung disease (HP:0006536)1.88501864
115Chronic obstructive pulmonary disease (HP:0006510)1.88501864
116Acute necrotizing encephalopathy (HP:0006965)1.85413105
117Orchitis (HP:0100796)1.85320664
118Glomerulopathy (HP:0100820)1.84479715
119Hyponatremia (HP:0002902)1.84100550
120Amaurosis fugax (HP:0100576)1.84063635
121Oral leukoplakia (HP:0002745)1.82068119
122Hemoptysis (HP:0002105)1.81959289
123Keratoconjunctivitis sicca (HP:0001097)1.80885544
124Carpal bone hypoplasia (HP:0001498)1.79627649
125Broad palm (HP:0001169)1.78296936
126Increased CSF protein (HP:0002922)1.77716936
127Type 2 muscle fiber atrophy (HP:0003554)1.76944972
128Muscle fiber atrophy (HP:0100295)1.76882616
129Urticaria (HP:0001025)1.76492380
130Aplasia/Hypoplasia of the thymus (HP:0010515)1.75972358
131Cutaneous melanoma (HP:0012056)1.73867723
132Reduced subcutaneous adipose tissue (HP:0003758)1.73602960
133Bronchiectasis (HP:0002110)1.71807792
134Hepatitis (HP:0012115)1.71385070
135Increased serum ferritin (HP:0003281)1.71354708
136Large earlobe (HP:0009748)1.70386341
137Pancreatic cysts (HP:0001737)1.69838740
138Decreased muscle mass (HP:0003199)1.68369074
139Asplenia (HP:0001746)1.67793844
140Abnormality of the neuromuscular junction (HP:0003398)1.66876013
141Fatigable weakness (HP:0003473)1.66876013
142Increased mean platelet volume (HP:0011877)1.65843726
143Chest pain (HP:0100749)1.64855456
144Dislocated radial head (HP:0003083)1.63677368

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.56504392
2MAP4K15.75669366
3ITK3.90181096
4BMPR23.57547492
5STK103.14424362
6ZAP703.00187189
7BCKDK2.86149125
8JAK32.83275026
9FGFR42.46931109
10CAMKK22.36382074
11GRK62.31341502
12TYK22.27702348
13MAP3K122.06992030
14TESK12.02897910
15NLK2.02873952
16IKBKE2.02868608
17MAP3K112.01927752
18TEC1.89143236
19EEF2K1.87140456
20LCK1.79159216
21CSK1.78903546
22MST41.73905520
23PINK11.71785883
24FGFR31.70576657
25JAK11.70066576
26LIMK11.68367068
27MAP3K131.58306921
28GRK71.57792263
29SYK1.53793988
30CAMKK11.52132556
31DMPK1.42215426
32BTK1.40834588
33LRRK21.39969446
34ZAK1.39531652
35BUB11.38030732
36MAP3K141.33724186
37IKBKB1.32251614
38HCK1.31069362
39MAP3K101.29541512
40TAOK31.24499036
41PRKCQ1.21001254
42PRKCH1.14128448
43SCYL21.14084457
44TBK11.08895555
45MAP2K61.03200611
46PKN21.02772204
47EPHB11.01961631
48MARK20.98881702
49CLK10.96933868
50GRK10.93892324
51BLK0.91850695
52VRK20.90908755
53MARK30.89756078
54MAP3K70.88661597
55PIM10.87526334
56PIK3CG0.87474582
57TAOK20.87038461
58TAOK10.86487394
59IRAK40.84307821
60FLT30.82311788
61WNK40.81853960
62RIPK40.81001184
63SIK20.80515915
64VRK10.80189573
65FES0.79997068
66PDGFRB0.79120541
67TRIB30.75823678
68NME20.75775591
69KIT0.75036440
70MYLK0.73586721
71MAPKAPK30.73067468
72STK40.72468323
73TLK10.72448516
74CDK40.72446614
75TGFBR20.70036402
76JAK20.68203721
77FGFR10.66278657
78EPHA30.66244217
79HIPK20.65405958
80LYN0.63297782
81ALK0.62400729
82PTK60.60298025
83PRKD20.58444975
84TIE10.57917913
85CDK90.57433980
86NUAK10.56958422
87PASK0.56948112
88CSF1R0.55893143
89TYRO30.55869038
90MELK0.55183268
91DAPK10.54264034
92IRAK10.53994056
93CDK190.53927176
94RPS6KA40.53294892
95PDK10.52513341
96MAPK70.51550040
97MAP4K20.51103084
98NME10.50731989
99FYN0.48910546
100MAP3K30.47957021
101TGFBR10.46262021
102CDK60.45702786
103INSR0.45339036
104CHUK0.44664427
105IGF1R0.44261565
106GSK3A0.42410950
107SRPK10.41883487
108KDR0.41598087
109TESK20.40639103
110MAPK30.39165098
111RPS6KB20.37827230
112MAPK120.37745963
113CDC70.36661622
114MAPK90.36247704
115ADRBK10.35399969
116CAMK10.35363356
117ROCK10.35264181
118MAPK110.35097400
119MAPK150.33213469
120MAP3K50.28736711
121MAP3K80.27190949
122CDK120.26803911
123BRSK20.26639082
124OBSCN0.26298352
125MAPK40.26272480
126TRPM70.26213964
127RET0.25901635
128SGK30.25178510
129ADRBK20.24182310
130INSRR0.23854014
131CAMK2A0.23638934
132SIK30.23468312
133RAF10.23035594
134PRKCA0.23017756
135FRK0.22910284
136ROCK20.22897720
137FGFR20.22124073
138MAPKAPK20.21619664
139IRAK20.21141935
140TNK20.20977348
141ILK0.20052602
142GRK50.19840927
143PRKACA0.18409536
144PAK40.18280907
145PIK3CA0.18258867
146AURKA0.17239547
147RPS6KA50.17191961
148MAPK80.16979811
149MATK0.16932856
150PRKD10.16148996
151EGFR0.15562071
152MAP3K10.14886154
153ABL10.12581050

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.60958493
2T cell receptor signaling pathway_Homo sapiens_hsa046604.73573634
3Graft-versus-host disease_Homo sapiens_hsa053323.48781170
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.37163676
5Measles_Homo sapiens_hsa051622.85660911
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.80899686
7Proteasome_Homo sapiens_hsa030502.72948170
8Antigen processing and presentation_Homo sapiens_hsa046122.66271785
9Allograft rejection_Homo sapiens_hsa053302.57355272
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.48963906
11Hematopoietic cell lineage_Homo sapiens_hsa046402.45493089
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.38608917
13Jak-STAT signaling pathway_Homo sapiens_hsa046302.03366455
14Osteoclast differentiation_Homo sapiens_hsa043801.85195927
15Type I diabetes mellitus_Homo sapiens_hsa049401.77023821
16Oxidative phosphorylation_Homo sapiens_hsa001901.65150225
17Leishmaniasis_Homo sapiens_hsa051401.64733441
18Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.60887725
19Viral myocarditis_Homo sapiens_hsa054161.58706588
20B cell receptor signaling pathway_Homo sapiens_hsa046621.58014251
21Autoimmune thyroid disease_Homo sapiens_hsa053201.55654092
22Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.55176647
23Chemokine signaling pathway_Homo sapiens_hsa040621.51891242
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.50000739
25Non-homologous end-joining_Homo sapiens_hsa034501.47536675
26Herpes simplex infection_Homo sapiens_hsa051681.45263101
27Acute myeloid leukemia_Homo sapiens_hsa052211.38139835
28Leukocyte transendothelial migration_Homo sapiens_hsa046701.37021523
29Pancreatic cancer_Homo sapiens_hsa052121.35659997
30Parkinsons disease_Homo sapiens_hsa050121.34511773
31Phototransduction_Homo sapiens_hsa047441.22201374
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.21758550
33TNF signaling pathway_Homo sapiens_hsa046681.20609463
34Toxoplasmosis_Homo sapiens_hsa051451.19883815
35Apoptosis_Homo sapiens_hsa042101.19067714
36Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.18943356
37Hepatitis B_Homo sapiens_hsa051611.17259767
38Toll-like receptor signaling pathway_Homo sapiens_hsa046201.13997288
39HTLV-I infection_Homo sapiens_hsa051661.13121545
40RNA polymerase_Homo sapiens_hsa030201.12595840
41NOD-like receptor signaling pathway_Homo sapiens_hsa046211.11525969
42Colorectal cancer_Homo sapiens_hsa052101.09790592
43Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08298067
44Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.07509590
45Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.07454242
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.06523135
47Ribosome_Homo sapiens_hsa030101.02871731
48Asthma_Homo sapiens_hsa053101.00793132
49Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.00164402
50Viral carcinogenesis_Homo sapiens_hsa052030.99215259
51Platelet activation_Homo sapiens_hsa046110.96743961
52Influenza A_Homo sapiens_hsa051640.95927795
53Alzheimers disease_Homo sapiens_hsa050100.94928807
54Shigellosis_Homo sapiens_hsa051310.93821676
55Chronic myeloid leukemia_Homo sapiens_hsa052200.91126717
56Nitrogen metabolism_Homo sapiens_hsa009100.90352163
57Thyroid cancer_Homo sapiens_hsa052160.85415521
58Prion diseases_Homo sapiens_hsa050200.85386890
59AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.84128278
60Epstein-Barr virus infection_Homo sapiens_hsa051690.81063968
61Hepatitis C_Homo sapiens_hsa051600.79411378
62Non-small cell lung cancer_Homo sapiens_hsa052230.72320828
63Phosphatidylinositol signaling system_Homo sapiens_hsa040700.67030643
64Notch signaling pathway_Homo sapiens_hsa043300.66180023
65Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64873409
66Neurotrophin signaling pathway_Homo sapiens_hsa047220.64698851
67VEGF signaling pathway_Homo sapiens_hsa043700.63299596
68Spliceosome_Homo sapiens_hsa030400.62498324
69Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61585300
70Caffeine metabolism_Homo sapiens_hsa002320.61354859
71Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60872951
72Prolactin signaling pathway_Homo sapiens_hsa049170.58719507
73Cardiac muscle contraction_Homo sapiens_hsa042600.58447689
74Linoleic acid metabolism_Homo sapiens_hsa005910.57705485
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57495249
76Huntingtons disease_Homo sapiens_hsa050160.57435732
77Salmonella infection_Homo sapiens_hsa051320.54558287
78Rheumatoid arthritis_Homo sapiens_hsa053230.54358464
79Tuberculosis_Homo sapiens_hsa051520.53346418
80Systemic lupus erythematosus_Homo sapiens_hsa053220.53282906
81Endometrial cancer_Homo sapiens_hsa052130.50874333
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49786978
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49442445
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.49331488
85African trypanosomiasis_Homo sapiens_hsa051430.49261959
86Legionellosis_Homo sapiens_hsa051340.49129530
87Inositol phosphate metabolism_Homo sapiens_hsa005620.47142978
88Small cell lung cancer_Homo sapiens_hsa052220.46518613
89Staphylococcus aureus infection_Homo sapiens_hsa051500.45574231
90Malaria_Homo sapiens_hsa051440.45206725
91Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.44203620
92DNA replication_Homo sapiens_hsa030300.43157400
93FoxO signaling pathway_Homo sapiens_hsa040680.41069619
94Prostate cancer_Homo sapiens_hsa052150.41018090
95MAPK signaling pathway_Homo sapiens_hsa040100.40352302
96Endocytosis_Homo sapiens_hsa041440.38027333
97Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.37960669
98MicroRNAs in cancer_Homo sapiens_hsa052060.37846114
99Mismatch repair_Homo sapiens_hsa034300.37163365
100p53 signaling pathway_Homo sapiens_hsa041150.36593095
101Insulin resistance_Homo sapiens_hsa049310.35195662
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.34768658
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33348798
104mTOR signaling pathway_Homo sapiens_hsa041500.32700816
105Pertussis_Homo sapiens_hsa051330.30930057
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30734610
107Rap1 signaling pathway_Homo sapiens_hsa040150.30640398
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30600880
109Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.29812567
110RNA degradation_Homo sapiens_hsa030180.27176409
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.27073083
112Renal cell carcinoma_Homo sapiens_hsa052110.26789286
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.26208505
114Drug metabolism - other enzymes_Homo sapiens_hsa009830.25621170
115Base excision repair_Homo sapiens_hsa034100.24981318
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.24943141
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.23908538
118Protein export_Homo sapiens_hsa030600.23701594
119Pyrimidine metabolism_Homo sapiens_hsa002400.22308808
120Alcoholism_Homo sapiens_hsa050340.20376482
121Pathways in cancer_Homo sapiens_hsa052000.20193364
122Homologous recombination_Homo sapiens_hsa034400.19955448
123Chemical carcinogenesis_Homo sapiens_hsa052040.19578045
124Olfactory transduction_Homo sapiens_hsa047400.19511178
125Proteoglycans in cancer_Homo sapiens_hsa052050.19377817
126One carbon pool by folate_Homo sapiens_hsa006700.19044239
127mRNA surveillance pathway_Homo sapiens_hsa030150.18583686
128Purine metabolism_Homo sapiens_hsa002300.17291063
129Lysine degradation_Homo sapiens_hsa003100.16926710
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16890277
131Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.15691800
132Phagosome_Homo sapiens_hsa041450.15260914
133Vascular smooth muscle contraction_Homo sapiens_hsa042700.14197994
134Retinol metabolism_Homo sapiens_hsa008300.13382115
135Ras signaling pathway_Homo sapiens_hsa040140.13233619
136Morphine addiction_Homo sapiens_hsa050320.10299001
137Collecting duct acid secretion_Homo sapiens_hsa049660.09525863
138Peroxisome_Homo sapiens_hsa041460.09116406
139ABC transporters_Homo sapiens_hsa020100.08479249
140Dorso-ventral axis formation_Homo sapiens_hsa043200.04656148
141Regulation of autophagy_Homo sapiens_hsa041400.03924963
142Amphetamine addiction_Homo sapiens_hsa050310.02083069

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