

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 7.33649250 |
| 2 | actin nucleation (GO:0045010) | 6.26912514 |
| 3 | DNA deamination (GO:0045006) | 6.07300557 |
| 4 | cytidine metabolic process (GO:0046087) | 5.76171527 |
| 5 | cytidine catabolic process (GO:0006216) | 5.76171527 |
| 6 | cytidine deamination (GO:0009972) | 5.76171527 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.71870031 |
| 8 | purine deoxyribonucleotide catabolic process (GO:0009155) | 5.65952065 |
| 9 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.65104536 |
| 10 | positive thymic T cell selection (GO:0045059) | 5.44289507 |
| 11 | negative T cell selection (GO:0043383) | 5.40074544 |
| 12 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.14570170 |
| 13 | negative thymic T cell selection (GO:0045060) | 5.01497232 |
| 14 | positive regulation of B cell differentiation (GO:0045579) | 4.99801089 |
| 15 | positive T cell selection (GO:0043368) | 4.91401001 |
| 16 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.86924979 |
| 17 | deoxyribonucleotide catabolic process (GO:0009264) | 4.54965145 |
| 18 | negative regulation of B cell apoptotic process (GO:0002903) | 4.52479754 |
| 19 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.42767737 |
| 20 | negative regulation of T cell apoptotic process (GO:0070233) | 4.36418555 |
| 21 | deoxyribose phosphate catabolic process (GO:0046386) | 4.32347026 |
| 22 | thymic T cell selection (GO:0045061) | 4.31175055 |
| 23 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.17790882 |
| 24 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.12316854 |
| 25 | sequestering of actin monomers (GO:0042989) | 4.09699166 |
| 26 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.08942137 |
| 27 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.05677003 |
| 28 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.05076356 |
| 29 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.02144797 |
| 30 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.94325611 |
| 31 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.92819331 |
| 32 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.92036173 |
| 33 | NIK/NF-kappaB signaling (GO:0038061) | 3.90369954 |
| 34 | T cell selection (GO:0045058) | 3.89033371 |
| 35 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.88094787 |
| 36 | immunoglobulin mediated immune response (GO:0016064) | 3.87606063 |
| 37 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.87401303 |
| 38 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.83691272 |
| 39 | regulation of B cell differentiation (GO:0045577) | 3.69998844 |
| 40 | T cell migration (GO:0072678) | 3.66864309 |
| 41 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.61873591 |
| 42 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.61873591 |
| 43 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.55399451 |
| 44 | response to interferon-beta (GO:0035456) | 3.53764234 |
| 45 | Peyers patch development (GO:0048541) | 3.53076629 |
| 46 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.53076629 |
| 47 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.49048246 |
| 48 | ribosomal small subunit assembly (GO:0000028) | 3.47599679 |
| 49 | positive regulation of lamellipodium assembly (GO:0010592) | 3.46905202 |
| 50 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.45635963 |
| 51 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.45390724 |
| 52 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.44049705 |
| 53 | positive regulation of interleukin-4 production (GO:0032753) | 3.31801383 |
| 54 | B cell receptor signaling pathway (GO:0050853) | 3.30914549 |
| 55 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.30397194 |
| 56 | regulation of gamma-delta T cell activation (GO:0046643) | 3.29854634 |
| 57 | T cell receptor signaling pathway (GO:0050852) | 3.28409770 |
| 58 | regulation of T cell tolerance induction (GO:0002664) | 3.26738840 |
| 59 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.25575210 |
| 60 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.25288493 |
| 61 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.23852613 |
| 62 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.22894583 |
| 63 | mature B cell differentiation involved in immune response (GO:0002313) | 3.22859143 |
| 64 | deoxyribose phosphate metabolic process (GO:0019692) | 3.22615049 |
| 65 | T cell costimulation (GO:0031295) | 3.21559380 |
| 66 | leukocyte aggregation (GO:0070486) | 3.20822246 |
| 67 | lymphocyte costimulation (GO:0031294) | 3.17581884 |
| 68 | B cell mediated immunity (GO:0019724) | 3.15416366 |
| 69 | positive regulation of tolerance induction (GO:0002645) | 3.14596521 |
| 70 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.14512288 |
| 71 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.12951287 |
| 72 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.12951287 |
| 73 | negative regulation of stress fiber assembly (GO:0051497) | 3.11757102 |
| 74 | regulation of T cell apoptotic process (GO:0070232) | 3.09869823 |
| 75 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.09352975 |
| 76 | cellular response to interferon-beta (GO:0035458) | 3.08679490 |
| 77 | purine nucleotide salvage (GO:0032261) | 3.07781058 |
| 78 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.06089744 |
| 79 | mast cell activation (GO:0045576) | 3.05981117 |
| 80 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.04639931 |
| 81 | negative regulation of viral genome replication (GO:0045071) | 3.03357091 |
| 82 | respiratory burst (GO:0045730) | 3.02807986 |
| 83 | nucleotide salvage (GO:0043173) | 3.02649564 |
| 84 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.02237546 |
| 85 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.00118436 |
| 86 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.99192641 |
| 87 | response to pheromone (GO:0019236) | 2.95339277 |
| 88 | mast cell degranulation (GO:0043303) | 2.94822093 |
| 89 | mast cell activation involved in immune response (GO:0002279) | 2.94822093 |
| 90 | regulation of interleukin-4 production (GO:0032673) | 2.94804797 |
| 91 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.92831877 |
| 92 | negative regulation of leukocyte apoptotic process (GO:2000107) | 2.92194086 |
| 93 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.90611115 |
| 94 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.88227255 |
| 95 | regulation of germinal center formation (GO:0002634) | 2.87620329 |
| 96 | regulation of lymphocyte apoptotic process (GO:0070228) | 2.86288905 |
| 97 | regulation of B cell apoptotic process (GO:0002902) | 2.83387551 |
| 98 | positive regulation of cell killing (GO:0031343) | 2.82955789 |
| 99 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.81949393 |
| 100 | regulation of activation of Janus kinase activity (GO:0010533) | 2.81431159 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.39488955 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.98137399 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.93757225 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.85904193 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.51519146 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.51108905 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.19047838 |
| 8 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.04897344 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.04381668 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.01843811 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.95075003 |
| 12 | MYB_26560356_Chip-Seq_TH2_Human | 2.80209250 |
| 13 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.76778690 |
| 14 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.70299734 |
| 15 | UTX_26944678_Chip-Seq_JUKART_Human | 2.60443885 |
| 16 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.39671701 |
| 17 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.34856253 |
| 18 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.19147471 |
| 19 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.17713637 |
| 20 | MYB_26560356_Chip-Seq_TH1_Human | 2.10803017 |
| 21 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.06038348 |
| 22 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.99612574 |
| 23 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.98807179 |
| 24 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.97690187 |
| 25 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.97390952 |
| 26 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.97211973 |
| 27 | MAF_26560356_Chip-Seq_TH1_Human | 1.89393274 |
| 28 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.89000416 |
| 29 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.85280147 |
| 30 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.83715847 |
| 31 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.78808640 |
| 32 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.75540489 |
| 33 | MAF_26560356_Chip-Seq_TH2_Human | 1.73632267 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73120841 |
| 35 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71693604 |
| 36 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.66873963 |
| 37 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.54279494 |
| 38 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.53366271 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50961078 |
| 40 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.50305602 |
| 41 | GATA3_26560356_Chip-Seq_TH2_Human | 1.49651916 |
| 42 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.47770114 |
| 43 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.46576092 |
| 44 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.46408727 |
| 45 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.45644706 |
| 46 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.42313182 |
| 47 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.40518353 |
| 48 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.39236960 |
| 49 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.39070707 |
| 50 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.38536856 |
| 51 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.38308181 |
| 52 | P300_27268052_Chip-Seq_Bcells_Human | 1.36921828 |
| 53 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.35443764 |
| 54 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.34496233 |
| 55 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.34141019 |
| 56 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.33421055 |
| 57 | MYC_22102868_ChIP-Seq_BL_Human | 1.28653791 |
| 58 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.28312063 |
| 59 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.23888187 |
| 60 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.21040445 |
| 61 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.18548596 |
| 62 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.18065674 |
| 63 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.17302923 |
| 64 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.16128138 |
| 65 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12774867 |
| 66 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.12487138 |
| 67 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.11407710 |
| 68 | SPI1_23127762_ChIP-Seq_K562_Human | 1.09618048 |
| 69 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.09329584 |
| 70 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.09269644 |
| 71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.08621960 |
| 72 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.07483526 |
| 73 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.07335340 |
| 74 | P68_20966046_ChIP-Seq_HELA_Human | 1.06953960 |
| 75 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.04156585 |
| 76 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.03822883 |
| 77 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.03242989 |
| 78 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01853113 |
| 79 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.00474798 |
| 80 | SA1_27219007_Chip-Seq_Bcells_Human | 0.99950694 |
| 81 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.99889806 |
| 82 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.99703675 |
| 83 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.99423725 |
| 84 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.97211535 |
| 85 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96098974 |
| 86 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.95916975 |
| 87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95100903 |
| 88 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.94800659 |
| 89 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.93787290 |
| 90 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92976892 |
| 91 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92055078 |
| 92 | ERA_21632823_ChIP-Seq_H3396_Human | 0.91105336 |
| 93 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.88039766 |
| 94 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.87917818 |
| 95 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 0.87772941 |
| 96 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86655429 |
| 97 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.86034319 |
| 98 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.85152950 |
| 99 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84478709 |
| 100 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.84337390 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.45836864 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.75920227 |
| 3 | MP0003763_abnormal_thymus_physiology | 3.30330986 |
| 4 | MP0009785_altered_susceptibility_to | 3.23325799 |
| 5 | MP0001800_abnormal_humoral_immune | 3.02850979 |
| 6 | MP0002638_abnormal_pupillary_reflex | 2.80311124 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.78177686 |
| 8 | MP0005025_abnormal_response_to | 2.77508781 |
| 9 | MP0002420_abnormal_adaptive_immunity | 2.77199929 |
| 10 | MP0001819_abnormal_immune_cell | 2.70019926 |
| 11 | MP0001790_abnormal_immune_system | 2.67919122 |
| 12 | MP0005387_immune_system_phenotype | 2.67919122 |
| 13 | MP0002723_abnormal_immune_serum | 2.62350919 |
| 14 | MP0002166_altered_tumor_susceptibility | 2.60848171 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 2.58547810 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 2.53761772 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 2.52090316 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.46949242 |
| 19 | MP0005075_abnormal_melanosome_morpholog | 2.31163751 |
| 20 | MP0002398_abnormal_bone_marrow | 2.31099223 |
| 21 | MP0003191_abnormal_cellular_cholesterol | 2.17985977 |
| 22 | MP0000716_abnormal_immune_system | 2.17918830 |
| 23 | MP0000685_abnormal_immune_system | 2.17773097 |
| 24 | MP0000689_abnormal_spleen_morphology | 1.94759669 |
| 25 | MP0002419_abnormal_innate_immunity | 1.94677958 |
| 26 | MP0002006_tumorigenesis | 1.93832746 |
| 27 | MP0002722_abnormal_immune_system | 1.85403851 |
| 28 | MP0002405_respiratory_system_inflammati | 1.84839663 |
| 29 | MP0001905_abnormal_dopamine_level | 1.83088139 |
| 30 | MP0003436_decreased_susceptibility_to | 1.80564023 |
| 31 | MP0003646_muscle_fatigue | 1.78286210 |
| 32 | MP0010155_abnormal_intestine_physiology | 1.75257993 |
| 33 | MP0000372_irregular_coat_pigmentation | 1.73494247 |
| 34 | MP0002429_abnormal_blood_cell | 1.72624898 |
| 35 | MP0000703_abnormal_thymus_morphology | 1.68093296 |
| 36 | MP0003806_abnormal_nucleotide_metabolis | 1.67297397 |
| 37 | MP0003866_abnormal_defecation | 1.66389765 |
| 38 | MP0001764_abnormal_homeostasis | 1.60704579 |
| 39 | MP0009697_abnormal_copulation | 1.58007076 |
| 40 | MP0001845_abnormal_inflammatory_respons | 1.49972815 |
| 41 | MP0005464_abnormal_platelet_physiology | 1.42890239 |
| 42 | MP0001873_stomach_inflammation | 1.39972501 |
| 43 | MP0003724_increased_susceptibility_to | 1.39496999 |
| 44 | MP0008469_abnormal_protein_level | 1.34681241 |
| 45 | MP0001853_heart_inflammation | 1.28688575 |
| 46 | MP0002933_joint_inflammation | 1.24235332 |
| 47 | MP0002138_abnormal_hepatobiliary_system | 1.20964704 |
| 48 | MP0009764_decreased_sensitivity_to | 1.19261007 |
| 49 | MP0004381_abnormal_hair_follicle | 1.18799547 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.18735348 |
| 51 | MP0005166_decreased_susceptibility_to | 1.16648140 |
| 52 | MP0003011_delayed_dark_adaptation | 1.15400469 |
| 53 | MP0008872_abnormal_physiological_respon | 1.14441954 |
| 54 | MP0003252_abnormal_bile_duct | 1.10750982 |
| 55 | MP0004145_abnormal_muscle_electrophysio | 1.10226830 |
| 56 | MP0002019_abnormal_tumor_incidence | 1.08614936 |
| 57 | MP0003448_altered_tumor_morphology | 1.07287773 |
| 58 | MP0005410_abnormal_fertilization | 1.03609427 |
| 59 | MP0003075_altered_response_to | 0.95868567 |
| 60 | MP0008877_abnormal_DNA_methylation | 0.94155256 |
| 61 | MP0000858_altered_metastatic_potential | 0.92890564 |
| 62 | MP0001968_abnormal_touch/_nociception | 0.92016113 |
| 63 | MP0002095_abnormal_skin_pigmentation | 0.90135919 |
| 64 | MP0000465_gastrointestinal_hemorrhage | 0.89749279 |
| 65 | MP0009763_increased_sensitivity_to | 0.88793088 |
| 66 | MP0006082_CNS_inflammation | 0.86751174 |
| 67 | MP0001533_abnormal_skeleton_physiology | 0.86611370 |
| 68 | MP0001986_abnormal_taste_sensitivity | 0.86468088 |
| 69 | MP0002277_abnormal_respiratory_mucosa | 0.85293152 |
| 70 | MP0005646_abnormal_pituitary_gland | 0.83534577 |
| 71 | MP0002396_abnormal_hematopoietic_system | 0.82508937 |
| 72 | MP0009379_abnormal_foot_pigmentation | 0.77378805 |
| 73 | MP0009643_abnormal_urine_homeostasis | 0.76327003 |
| 74 | MP0006036_abnormal_mitochondrial_physio | 0.74444806 |
| 75 | MP0004947_skin_inflammation | 0.73902029 |
| 76 | MP0002693_abnormal_pancreas_physiology | 0.73315435 |
| 77 | MP0005376_homeostasis/metabolism_phenot | 0.72544325 |
| 78 | MP0009278_abnormal_bone_marrow | 0.71631067 |
| 79 | MP0004147_increased_porphyrin_level | 0.69073450 |
| 80 | MP0005266_abnormal_metabolism | 0.67501255 |
| 81 | MP0008873_increased_physiological_sensi | 0.64161606 |
| 82 | MP0005084_abnormal_gallbladder_morpholo | 0.64030610 |
| 83 | MP0003183_abnormal_peptide_metabolism | 0.63808555 |
| 84 | MP0005377_hearing/vestibular/ear_phenot | 0.63772832 |
| 85 | MP0003878_abnormal_ear_physiology | 0.63772832 |
| 86 | MP0003786_premature_aging | 0.62256279 |
| 87 | MP0003137_abnormal_impulse_conducting | 0.61773074 |
| 88 | MP0002009_preneoplasia | 0.60807510 |
| 89 | MP0005253_abnormal_eye_physiology | 0.60512639 |
| 90 | MP0005551_abnormal_eye_electrophysiolog | 0.59679634 |
| 91 | MP0000639_abnormal_adrenal_gland | 0.59338644 |
| 92 | MP0001542_abnormal_bone_strength | 0.56990688 |
| 93 | MP0005330_cardiomyopathy | 0.56891582 |
| 94 | MP0005397_hematopoietic_system_phenotyp | 0.56029369 |
| 95 | MP0001545_abnormal_hematopoietic_system | 0.56029369 |
| 96 | MP0002822_catalepsy | 0.53598946 |
| 97 | MP0001663_abnormal_digestive_system | 0.53544611 |
| 98 | MP0005319_abnormal_enzyme/_coenzyme | 0.52911679 |
| 99 | MP0000604_amyloidosis | 0.52592167 |
| 100 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.51887238 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Agammaglobulinemia (HP:0004432) | 7.23079231 |
| 2 | Aplastic anemia (HP:0001915) | 5.94125098 |
| 3 | Severe combined immunodeficiency (HP:0004430) | 5.91937256 |
| 4 | Combined immunodeficiency (HP:0005387) | 4.75640606 |
| 5 | Abnormality of B cell number (HP:0010975) | 4.74123077 |
| 6 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.72892600 |
| 7 | Autoimmune hemolytic anemia (HP:0001890) | 4.45665230 |
| 8 | B lymphocytopenia (HP:0010976) | 4.42875911 |
| 9 | IgG deficiency (HP:0004315) | 4.13514918 |
| 10 | Increased IgM level (HP:0003496) | 4.11401428 |
| 11 | T lymphocytopenia (HP:0005403) | 4.01839457 |
| 12 | Thyroiditis (HP:0100646) | 3.89983129 |
| 13 | Meningitis (HP:0001287) | 3.88566292 |
| 14 | Abnormality of T cell number (HP:0011839) | 3.77534566 |
| 15 | Recurrent bronchitis (HP:0002837) | 3.52378360 |
| 16 | Autoimmune thrombocytopenia (HP:0001973) | 3.49711174 |
| 17 | Panhypogammaglobulinemia (HP:0003139) | 3.45610845 |
| 18 | Hypoproteinemia (HP:0003075) | 3.31586641 |
| 19 | Abnormality of T cells (HP:0002843) | 3.29487693 |
| 20 | Increased IgE level (HP:0003212) | 3.25795534 |
| 21 | Cerebral palsy (HP:0100021) | 3.25690374 |
| 22 | Abnormality of eosinophils (HP:0001879) | 3.25263734 |
| 23 | Recurrent fungal infections (HP:0002841) | 3.22551535 |
| 24 | Mitochondrial inheritance (HP:0001427) | 3.20364703 |
| 25 | Cellulitis (HP:0100658) | 3.18642924 |
| 26 | Encephalitis (HP:0002383) | 3.15450793 |
| 27 | Hypergammaglobulinemia (HP:0010702) | 3.13856197 |
| 28 | Granulocytopenia (HP:0001913) | 3.13552066 |
| 29 | Eosinophilia (HP:0001880) | 3.08784981 |
| 30 | Recurrent viral infections (HP:0004429) | 3.05967669 |
| 31 | Sepsis (HP:0100806) | 2.97002768 |
| 32 | Mesangial abnormality (HP:0001966) | 2.96562075 |
| 33 | Chronic sinusitis (HP:0011109) | 2.96500662 |
| 34 | Recurrent pneumonia (HP:0006532) | 2.93639901 |
| 35 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.92570413 |
| 36 | Acute necrotizing encephalopathy (HP:0006965) | 2.90120004 |
| 37 | Chronic obstructive pulmonary disease (HP:0006510) | 2.85876184 |
| 38 | Obstructive lung disease (HP:0006536) | 2.85876184 |
| 39 | Eczematoid dermatitis (HP:0000976) | 2.82629810 |
| 40 | Verrucae (HP:0200043) | 2.81339863 |
| 41 | Papilloma (HP:0012740) | 2.81339863 |
| 42 | Recurrent cutaneous fungal infections (HP:0011370) | 2.71570694 |
| 43 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.71570694 |
| 44 | Pancytopenia (HP:0001876) | 2.71438200 |
| 45 | Lymphopenia (HP:0001888) | 2.70008160 |
| 46 | Leukocytosis (HP:0001974) | 2.67014283 |
| 47 | Abnormality of the prostate (HP:0008775) | 2.66983111 |
| 48 | Hepatocellular necrosis (HP:0001404) | 2.66236902 |
| 49 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.65562988 |
| 50 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.61180072 |
| 51 | Oral leukoplakia (HP:0002745) | 2.56619551 |
| 52 | Increased intramyocellular lipid droplets (HP:0012240) | 2.55299099 |
| 53 | Skin rash (HP:0000988) | 2.52431700 |
| 54 | Type I transferrin isoform profile (HP:0003642) | 2.48760818 |
| 55 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.46615313 |
| 56 | 3-Methylglutaconic aciduria (HP:0003535) | 2.46188102 |
| 57 | Amyotrophic lateral sclerosis (HP:0007354) | 2.45061521 |
| 58 | Increased CSF lactate (HP:0002490) | 2.44821792 |
| 59 | Chronic diarrhea (HP:0002028) | 2.44549909 |
| 60 | Lymphoma (HP:0002665) | 2.42839173 |
| 61 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.42514230 |
| 62 | Abnormality of macrophages (HP:0004311) | 2.42326838 |
| 63 | Hypoplasia of the thymus (HP:0000778) | 2.41969013 |
| 64 | Recurrent lower respiratory tract infections (HP:0002783) | 2.41943276 |
| 65 | Stomatitis (HP:0010280) | 2.41494022 |
| 66 | Acute hepatic failure (HP:0006554) | 2.40957686 |
| 67 | IgM deficiency (HP:0002850) | 2.40496195 |
| 68 | Progressive macrocephaly (HP:0004481) | 2.36289260 |
| 69 | Abnormality of T cell physiology (HP:0011840) | 2.35081936 |
| 70 | Increased muscle lipid content (HP:0009058) | 2.33513654 |
| 71 | Prostate neoplasm (HP:0100787) | 2.33372506 |
| 72 | Hepatic necrosis (HP:0002605) | 2.32787506 |
| 73 | Petechiae (HP:0000967) | 2.29546047 |
| 74 | Acute encephalopathy (HP:0006846) | 2.24159061 |
| 75 | Bronchitis (HP:0012387) | 2.23327556 |
| 76 | Congenital stationary night blindness (HP:0007642) | 2.20412144 |
| 77 | Mediastinal lymphadenopathy (HP:0100721) | 2.19751465 |
| 78 | Recurrent bacterial skin infections (HP:0005406) | 2.19308725 |
| 79 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.19205867 |
| 80 | Myositis (HP:0100614) | 2.15895873 |
| 81 | Cerebral edema (HP:0002181) | 2.15870016 |
| 82 | Osteomyelitis (HP:0002754) | 2.06700155 |
| 83 | Increased hepatocellular lipid droplets (HP:0006565) | 2.03198467 |
| 84 | Pustule (HP:0200039) | 2.01075852 |
| 85 | Recurrent otitis media (HP:0000403) | 2.00874247 |
| 86 | Thrombocytosis (HP:0001894) | 2.00183530 |
| 87 | Renal Fanconi syndrome (HP:0001994) | 1.99505666 |
| 88 | Recurrent abscess formation (HP:0002722) | 1.98684881 |
| 89 | Decreased central vision (HP:0007663) | 1.97664176 |
| 90 | Inflammation of the large intestine (HP:0002037) | 1.97408739 |
| 91 | Dicarboxylic aciduria (HP:0003215) | 1.94440092 |
| 92 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.94440092 |
| 93 | Cellular immunodeficiency (HP:0005374) | 1.92755787 |
| 94 | Abnormal protein glycosylation (HP:0012346) | 1.92695653 |
| 95 | Abnormal glycosylation (HP:0012345) | 1.92695653 |
| 96 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.92695653 |
| 97 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.92695653 |
| 98 | Recurrent skin infections (HP:0001581) | 1.92197347 |
| 99 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.89010702 |
| 100 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.87557978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 7.18466422 |
| 2 | KDR | 6.59267617 |
| 3 | SCYL2 | 3.79286087 |
| 4 | TESK1 | 3.37227682 |
| 5 | TXK | 3.36588093 |
| 6 | VRK2 | 3.08658613 |
| 7 | MAP3K11 | 2.60031020 |
| 8 | IKBKE | 2.43496129 |
| 9 | LIMK1 | 2.29559740 |
| 10 | MAP4K1 | 2.22528476 |
| 11 | MUSK | 1.98330017 |
| 12 | TAOK3 | 1.87841724 |
| 13 | BCKDK | 1.83363715 |
| 14 | MAP4K2 | 1.71432316 |
| 15 | MAP3K12 | 1.66536756 |
| 16 | PASK | 1.62140379 |
| 17 | KIT | 1.61350065 |
| 18 | ZAP70 | 1.59629470 |
| 19 | ITK | 1.55642483 |
| 20 | SYK | 1.52450402 |
| 21 | TBK1 | 1.45058601 |
| 22 | STK16 | 1.44829960 |
| 23 | FES | 1.35330756 |
| 24 | PIM2 | 1.25512943 |
| 25 | BTK | 1.23862322 |
| 26 | LCK | 1.23662180 |
| 27 | ERN1 | 1.15811416 |
| 28 | VRK1 | 1.10793429 |
| 29 | GRK6 | 1.09932224 |
| 30 | TNK2 | 1.09137892 |
| 31 | LYN | 1.08168241 |
| 32 | TEC | 1.08063037 |
| 33 | NME2 | 1.05109763 |
| 34 | PRKCQ | 0.98504554 |
| 35 | NUAK1 | 0.94031986 |
| 36 | BLK | 0.91594627 |
| 37 | MAPK13 | 0.91572935 |
| 38 | JAK3 | 0.90749387 |
| 39 | BMPR2 | 0.90645057 |
| 40 | ADRBK2 | 0.89028111 |
| 41 | CSF1R | 0.87261423 |
| 42 | MARK3 | 0.86661453 |
| 43 | ARAF | 0.85416066 |
| 44 | GRK7 | 0.84066161 |
| 45 | TYK2 | 0.83784554 |
| 46 | IRAK4 | 0.80780020 |
| 47 | IKBKB | 0.77651432 |
| 48 | TAF1 | 0.75934833 |
| 49 | PIM1 | 0.73734000 |
| 50 | ZAK | 0.67942053 |
| 51 | DAPK1 | 0.67093867 |
| 52 | CSK | 0.62386857 |
| 53 | TIE1 | 0.57092219 |
| 54 | LRRK2 | 0.55521402 |
| 55 | RIPK4 | 0.53649096 |
| 56 | GRK1 | 0.53601220 |
| 57 | FYN | 0.52968925 |
| 58 | MYLK | 0.50900774 |
| 59 | HCK | 0.50528293 |
| 60 | STK10 | 0.45344459 |
| 61 | CLK1 | 0.45304192 |
| 62 | PIK3CG | 0.45216815 |
| 63 | CDK8 | 0.41607743 |
| 64 | SIK2 | 0.41548111 |
| 65 | MAP3K5 | 0.40591534 |
| 66 | INSRR | 0.39999713 |
| 67 | NLK | 0.39679661 |
| 68 | AURKA | 0.39494211 |
| 69 | RPS6KA5 | 0.39051244 |
| 70 | MAPK11 | 0.38047437 |
| 71 | SIK3 | 0.36105446 |
| 72 | PIK3CA | 0.34375216 |
| 73 | MAPKAPK3 | 0.32918933 |
| 74 | MAPKAPK5 | 0.30365055 |
| 75 | GRK5 | 0.30210519 |
| 76 | ATR | 0.30170212 |
| 77 | ADRBK1 | 0.28486684 |
| 78 | TAOK2 | 0.28048890 |
| 79 | OBSCN | 0.26526169 |
| 80 | CAMKK1 | 0.26451965 |
| 81 | TLK1 | 0.25751170 |
| 82 | IGF1R | 0.24311219 |
| 83 | CDK19 | 0.23715246 |
| 84 | PRKCH | 0.23564195 |
| 85 | PRKCA | 0.23544583 |
| 86 | MAPKAPK2 | 0.23330475 |
| 87 | ROCK1 | 0.22893541 |
| 88 | PRKCI | 0.22817675 |
| 89 | MAP3K3 | 0.22794901 |
| 90 | PAK1 | 0.22698335 |
| 91 | MAPK15 | 0.21962690 |
| 92 | MAP2K6 | 0.21600527 |
| 93 | INSR | 0.21155918 |
| 94 | CSNK2A2 | 0.20873853 |
| 95 | MST4 | 0.20819113 |
| 96 | PRKD1 | 0.20742694 |
| 97 | FLT3 | 0.19750947 |
| 98 | CSNK2A1 | 0.19732341 |
| 99 | MAPK12 | 0.15109434 |
| 100 | PKN1 | 0.15100558 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 7.11029408 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.82268795 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.03576988 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.92382840 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.89245048 |
| 6 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.86480796 |
| 7 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.62720203 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.56509972 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.49302394 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.39969833 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.27015450 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.22761598 |
| 13 | Ribosome_Homo sapiens_hsa03010 | 2.13865820 |
| 14 | Asthma_Homo sapiens_hsa05310 | 2.00172921 |
| 15 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.94859401 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.77877449 |
| 17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.56694144 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.49988379 |
| 19 | Base excision repair_Homo sapiens_hsa03410 | 1.48702037 |
| 20 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.46302579 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.43332577 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.41582237 |
| 23 | Measles_Homo sapiens_hsa05162 | 1.39979997 |
| 24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.38685082 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.35599500 |
| 26 | Shigellosis_Homo sapiens_hsa05131 | 1.33745323 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.31625839 |
| 28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.29185720 |
| 29 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.24560289 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.22820085 |
| 31 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.21982496 |
| 32 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.19310985 |
| 33 | RNA polymerase_Homo sapiens_hsa03020 | 1.18419852 |
| 34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.13169934 |
| 35 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.08213133 |
| 36 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.07241981 |
| 37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.06763797 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.06564679 |
| 39 | Leishmaniasis_Homo sapiens_hsa05140 | 1.05479196 |
| 40 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.98596606 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.97358985 |
| 42 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.91348320 |
| 43 | Salmonella infection_Homo sapiens_hsa05132 | 0.90516136 |
| 44 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.89246671 |
| 45 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.86843429 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 0.85319862 |
| 47 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.81924506 |
| 48 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.81866761 |
| 49 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.80261936 |
| 50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.75257110 |
| 51 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.73079373 |
| 52 | Mismatch repair_Homo sapiens_hsa03430 | 0.70305134 |
| 53 | Purine metabolism_Homo sapiens_hsa00230 | 0.66078688 |
| 54 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.62947845 |
| 55 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.62738867 |
| 56 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.61817433 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60535672 |
| 58 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.59240967 |
| 59 | Pertussis_Homo sapiens_hsa05133 | 0.57280195 |
| 60 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.55298104 |
| 61 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.55073084 |
| 62 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.54659020 |
| 63 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.54518544 |
| 64 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.54188976 |
| 65 | Influenza A_Homo sapiens_hsa05164 | 0.47011545 |
| 66 | Retinol metabolism_Homo sapiens_hsa00830 | 0.46011321 |
| 67 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.45403986 |
| 68 | Platelet activation_Homo sapiens_hsa04611 | 0.44350665 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.43648505 |
| 70 | Tuberculosis_Homo sapiens_hsa05152 | 0.42531955 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40117105 |
| 72 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.40066152 |
| 73 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.38026892 |
| 74 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.37991935 |
| 75 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.37732028 |
| 76 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36874555 |
| 77 | HTLV-I infection_Homo sapiens_hsa05166 | 0.36124124 |
| 78 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.34561646 |
| 79 | Taste transduction_Homo sapiens_hsa04742 | 0.31879207 |
| 80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.31069143 |
| 81 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.30262856 |
| 82 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.26830227 |
| 83 | Phagosome_Homo sapiens_hsa04145 | 0.25305423 |
| 84 | RNA degradation_Homo sapiens_hsa03018 | 0.25185437 |
| 85 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.24777630 |
| 86 | Metabolic pathways_Homo sapiens_hsa01100 | 0.24724728 |
| 87 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.24280669 |
| 88 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.23934638 |
| 89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.22784027 |
| 90 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.22356004 |
| 91 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.22036694 |
| 92 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.20977651 |
| 93 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.20872898 |
| 94 | Spliceosome_Homo sapiens_hsa03040 | 0.20633545 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.20564242 |
| 96 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.20440312 |
| 97 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.19986160 |
| 98 | Endocytosis_Homo sapiens_hsa04144 | 0.19715084 |
| 99 | Sulfur relay system_Homo sapiens_hsa04122 | 0.17318633 |
| 100 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.16456630 |

