TRBJ2-4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)9.82869866
2negative thymic T cell selection (GO:0045060)9.19304156
3regulation of isotype switching to IgG isotypes (GO:0048302)8.41772167
4negative regulation of cell killing (GO:0031342)7.72831520
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.72831520
6positive regulation of gamma-delta T cell activation (GO:0046645)7.65639513
7thymic T cell selection (GO:0045061)7.39677637
8positive T cell selection (GO:0043368)7.24350037
9cytidine deamination (GO:0009972)7.14232513
10cytidine metabolic process (GO:0046087)7.14232513
11cytidine catabolic process (GO:0006216)7.14232513
12positive thymic T cell selection (GO:0045059)7.08858303
13T cell migration (GO:0072678)7.08574871
14T cell selection (GO:0045058)6.98086766
15regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.84880243
16positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.66985188
17DNA deamination (GO:0045006)6.50384783
18positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.42065412
19pyrimidine ribonucleoside catabolic process (GO:0046133)6.19442713
20positive regulation of B cell differentiation (GO:0045579)6.18008092
21regulation of gamma-delta T cell differentiation (GO:0045586)6.17058578
22response to interleukin-15 (GO:0070672)6.14726107
23interferon-gamma production (GO:0032609)5.72967063
24T cell receptor signaling pathway (GO:0050852)5.62822130
25cellular response to interleukin-15 (GO:0071350)5.53873868
26regulation of gamma-delta T cell activation (GO:0046643)5.52220254
27regulation of activation of Janus kinase activity (GO:0010533)5.48969242
28positive regulation of alpha-beta T cell proliferation (GO:0046641)5.45102895
29positive regulation of isotype switching (GO:0045830)5.43972137
30regulation of alpha-beta T cell proliferation (GO:0046640)5.32074937
31regulation of T cell tolerance induction (GO:0002664)5.17034677
32T cell costimulation (GO:0031295)5.10507332
33antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.02570427
34antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.02570427
35lymphocyte costimulation (GO:0031294)5.00965814
36actin nucleation (GO:0045010)4.97939938
37negative regulation of T cell apoptotic process (GO:0070233)4.94467516
38activated T cell proliferation (GO:0050798)4.86385757
39regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.83223384
40positive regulation of B cell mediated immunity (GO:0002714)4.78847136
41positive regulation of immunoglobulin mediated immune response (GO:0002891)4.78847136
42regulation of B cell differentiation (GO:0045577)4.76227305
43antigen receptor-mediated signaling pathway (GO:0050851)4.69524182
44negative regulation by host of viral transcription (GO:0043922)4.68809715
45positive regulation of DNA recombination (GO:0045911)4.67837369
46mast cell activation (GO:0045576)4.60392378
47heterotypic cell-cell adhesion (GO:0034113)4.59752446
48ribosomal small subunit assembly (GO:0000028)4.53589324
49leukocyte aggregation (GO:0070486)4.51970647
50regulation of interleukin-2 biosynthetic process (GO:0045076)4.51885445
51positive regulation of inflammatory response to antigenic stimulus (GO:0002863)4.49194215
52positive regulation of humoral immune response (GO:0002922)4.47114902
53positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.45913911
54positive regulation of natural killer cell mediated immunity (GO:0002717)4.45913911
55eosinophil chemotaxis (GO:0048245)4.40496196
56antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.37873870
57pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.34520127
58regulation of isotype switching (GO:0045191)4.32160658
59negative regulation of T cell mediated immunity (GO:0002710)4.31359574
60regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.24714159
61regulation of natural killer cell mediated immunity (GO:0002715)4.24714159
62antigen processing and presentation of endogenous antigen (GO:0019883)4.19543692
63regulation of T cell receptor signaling pathway (GO:0050856)4.19008547
64lymphocyte migration (GO:0072676)4.18837122
65positive regulation of tolerance induction (GO:0002645)4.14976529
66deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.12855016
67positive regulation of immunoglobulin production (GO:0002639)4.10609275
68regulation of chronic inflammatory response (GO:0002676)4.07233272
69megakaryocyte development (GO:0035855)4.05072722
70Arp2/3 complex-mediated actin nucleation (GO:0034314)4.03451821
71regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.01053749
72eosinophil migration (GO:0072677)3.99717227
73regulation of immunoglobulin mediated immune response (GO:0002889)3.99423751
74positive regulation of interleukin-2 production (GO:0032743)3.98741695
75chaperone-mediated protein transport (GO:0072321)3.97342077
76signal complex assembly (GO:0007172)3.97319616
77T cell differentiation (GO:0030217)3.92399540
78negative regulation of lymphocyte apoptotic process (GO:0070229)3.87853992
79regulation of B cell mediated immunity (GO:0002712)3.85245399
80monocyte chemotaxis (GO:0002548)3.83580571
81positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.83170422
82positive regulation of monocyte chemotaxis (GO:0090026)3.78315577
83regulation of B cell receptor signaling pathway (GO:0050855)3.77834432
84leukocyte cell-cell adhesion (GO:0007159)3.73484308
85regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.69245663
86regulation of leukocyte mediated cytotoxicity (GO:0001910)3.68567542
87SMAD protein complex assembly (GO:0007183)3.68177523
88regulation of regulatory T cell differentiation (GO:0045589)3.65498214
89natural killer cell differentiation (GO:0001779)3.61610504
90regulation of tolerance induction (GO:0002643)3.60603525
91pyrimidine nucleotide catabolic process (GO:0006244)3.60277282
92Peyers patch development (GO:0048541)3.56537961
93mucosal-associated lymphoid tissue development (GO:0048537)3.56537961
94positive regulation of T cell apoptotic process (GO:0070234)3.55519851
95alpha-beta T cell activation (GO:0046631)3.55472734
96T cell activation (GO:0042110)3.55075210
97regulation of immunoglobulin production (GO:0002637)3.53289848
98sequestering of actin monomers (GO:0042989)3.53014813
99alpha-beta T cell differentiation (GO:0046632)3.50992395
100mast cell activation involved in immune response (GO:0002279)3.50153499
101mast cell degranulation (GO:0043303)3.50153499
102regulation of transforming growth factor beta2 production (GO:0032909)3.49659747
103pyrimidine nucleoside catabolic process (GO:0046135)3.47934708
104peroxisome fission (GO:0016559)3.47687679
105T cell proliferation (GO:0042098)3.46817375
106deoxyribose phosphate catabolic process (GO:0046386)3.43865339
107positive regulation of cell killing (GO:0031343)3.43796384
108deoxyribonucleotide catabolic process (GO:0009264)3.38993445
109V(D)J recombination (GO:0033151)3.37641538
110regulation of T cell apoptotic process (GO:0070232)3.36174921
111negative regulation of B cell proliferation (GO:0030889)3.34219037
112regulation of cell killing (GO:0031341)3.33061226
113negative regulation of viral genome replication (GO:0045071)3.32791704
114immune response-activating cell surface receptor signaling pathway (GO:0002429)3.32470388
115positive regulation of T cell chemotaxis (GO:0010820)3.31720010
116regulation of T cell chemotaxis (GO:0010819)3.31720010
117regulation of defense response to virus by virus (GO:0050690)3.31625845
118purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.31137911
119positive regulation of interleukin-17 production (GO:0032740)3.23009491
120positive regulation of lymphocyte mediated immunity (GO:0002708)3.22485656
121positive regulation of natural killer cell differentiation (GO:0032825)3.20308088
122dendritic cell chemotaxis (GO:0002407)3.17978305
123macrophage chemotaxis (GO:0048246)3.15862390
124regulation of lymphocyte chemotaxis (GO:1901623)3.15749732
125immunoglobulin mediated immune response (GO:0016064)3.14457095
126B cell receptor signaling pathway (GO:0050853)3.14418179
127positive regulation of cell adhesion mediated by integrin (GO:0033630)3.13619605
128cellular response to interleukin-4 (GO:0071353)3.12609435
129base-excision repair, AP site formation (GO:0006285)3.12218881
130positive regulation of interleukin-8 secretion (GO:2000484)3.11684181
131negative regulation of lymphocyte mediated immunity (GO:0002707)3.09249735
132positive regulation of gluconeogenesis (GO:0045722)3.08820183
133regulation of macrophage chemotaxis (GO:0010758)3.08592261
134purine deoxyribonucleotide catabolic process (GO:0009155)3.08477283
135regulation of response to tumor cell (GO:0002834)3.07769847
136positive regulation of response to tumor cell (GO:0002836)3.07769847
137positive regulation of immune response to tumor cell (GO:0002839)3.07769847
138regulation of immune response to tumor cell (GO:0002837)3.07769847
139leukocyte tethering or rolling (GO:0050901)3.07717357
140regulation of calcium-mediated signaling (GO:0050848)3.06060030
141positive regulation of defense response to virus by host (GO:0002230)3.03584070
142positive regulation of calcium-mediated signaling (GO:0050850)3.02073019
143cellular defense response (GO:0006968)3.00330685
144T cell homeostasis (GO:0043029)3.00036471
145regulation of T cell mediated cytotoxicity (GO:0001914)2.97868990
146negative regulation of T cell receptor signaling pathway (GO:0050860)2.97816957
147negative regulation of B cell apoptotic process (GO:0002903)2.97072028
148negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.95951851
149regulation of interleukin-2 production (GO:0032663)2.94879346
150pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.94368915
151regulation of lymphocyte mediated immunity (GO:0002706)2.92180147
152regulation of chemokine-mediated signaling pathway (GO:0070099)2.89429944
153positive regulation of lymphocyte migration (GO:2000403)2.89207903
154regulation of mononuclear cell migration (GO:0071675)2.87739203
155negative regulation of leukocyte apoptotic process (GO:2000107)2.87454491
1562-deoxyribonucleotide metabolic process (GO:0009394)2.84506088
157regulation of monocyte chemotaxis (GO:0090025)2.82950619
158DNA dealkylation (GO:0035510)2.82419549
159DNA demethylation (GO:0080111)2.82191274
160positive regulation of translational initiation (GO:0045948)2.81472112

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse9.27817533
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse7.33743912
3E2F7_22180533_ChIP-Seq_HELA_Human6.91285932
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.35823667
5RUNX_20019798_ChIP-Seq_JUKART_Human4.16647847
6STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.88597636
7MYC_22102868_ChIP-Seq_BL_Human3.75168439
8FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.65719166
9IRF8_22096565_ChIP-ChIP_GC-B_Human3.64780463
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.62080700
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.42213516
12STAT4_19710469_ChIP-ChIP_TH1__Mouse3.29946891
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.28327547
14MYB_26560356_Chip-Seq_TH2_Human3.22934346
15MAF_26560356_Chip-Seq_TH1_Human2.82281688
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.81510951
17UTX_26944678_Chip-Seq_JUKART_Human2.60550430
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.57358040
19MYB_26560356_Chip-Seq_TH1_Human2.51974435
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.44850789
21GATA3_27048872_Chip-Seq_THYMUS_Human2.36003378
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.12358763
23JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.02961384
24RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.01197403
25SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.00190462
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.96144790
27KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.96036940
28IRF8_21731497_ChIP-ChIP_J774_Mouse1.89997265
29MAF_26560356_Chip-Seq_TH2_Human1.84555946
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83911402
31SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.79723704
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77904553
33SPI1_23547873_ChIP-Seq_NB4_Human1.77763783
34E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.76361166
35RUNX1_22412390_ChIP-Seq_EML_Mouse1.71196324
36VDR_24763502_ChIP-Seq_THP-1_Human1.65764231
37VDR_21846776_ChIP-Seq_THP-1_Human1.64105829
38GABP_17652178_ChIP-ChIP_JURKAT_Human1.63858487
39NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.62994144
40KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.60321495
41MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.60062248
42ELF1_20517297_ChIP-Seq_JURKAT_Human1.58233284
43RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.55464203
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53778521
45TCF7_22412390_ChIP-Seq_EML_Mouse1.53481195
46KDM2B_26808549_Chip-Seq_DND41_Human1.52773996
47MYB_21317192_ChIP-Seq_ERMYB_Mouse1.50483500
48EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.46522912
49BCL6_27268052_Chip-Seq_Bcells_Human1.45415976
50VDR_22108803_ChIP-Seq_LS180_Human1.45296609
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43823060
52SCL_19346495_ChIP-Seq_HPC-7_Human1.43736962
53TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42350994
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40613014
55IRF8_27001747_Chip-Seq_BMDM_Mouse1.38312282
56NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.34431548
57TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.34031205
58KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.32399009
59MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.31853287
60RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.31680058
61ETS1_20019798_ChIP-Seq_JURKAT_Human1.27647628
62CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.26953524
63P300_27268052_Chip-Seq_Bcells_Human1.25013305
64GATA3_26560356_Chip-Seq_TH2_Human1.20829786
65SPI1_23127762_ChIP-Seq_K562_Human1.15469394
66CIITA_25753668_ChIP-Seq_RAJI_Human1.15091493
67YY1_22570637_ChIP-Seq_MALME-3M_Human1.14658827
68EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.14572733
69KDM2B_26808549_Chip-Seq_SUP-B15_Human1.14056367
70TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.12301220
71SRF_21415370_ChIP-Seq_HL-1_Mouse1.12178675
72BCOR_27268052_Chip-Seq_Bcells_Human1.11863275
73VDR_24787735_ChIP-Seq_THP-1_Human1.11117297
74NANOG_20526341_ChIP-Seq_ESCs_Human1.10617054
75HOXB4_20404135_ChIP-ChIP_EML_Mouse1.09784277
76PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.07098740
77BP1_19119308_ChIP-ChIP_Hs578T_Human1.04858012
78CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03520209
79ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02816330
80PU_27001747_Chip-Seq_BMDM_Mouse1.02517789
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99371713
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.99123275
83HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.98790767
84ELK1_19687146_ChIP-ChIP_HELA_Human0.98754198
85LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.98337302
86BRD4_27068464_Chip-Seq_AML-cells_Mouse0.96344804
87GATA1_19941826_ChIP-Seq_K562_Human0.95401415
88CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.95380057
89ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95360830
90NOTCH1_21737748_ChIP-Seq_TLL_Human0.95317396
91CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.95147449
92VDR_23849224_ChIP-Seq_CD4+_Human0.94283291
93CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94089554
94PU.1_20513432_ChIP-Seq_Bcells_Mouse0.92583635
95VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.92468476
96GATA1_22025678_ChIP-Seq_K562_Human0.92276436
97PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.91918308
98LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.90960706
99KDM2B_26808549_Chip-Seq_JURKAT_Human0.90379124
100GATA2_22383799_ChIP-Seq_G1ME_Mouse0.87038004
101GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86256014
102SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.85727439
103PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.85570526
104RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.85549410
105E2F4_17652178_ChIP-ChIP_JURKAT_Human0.84686046
106RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84355847
107CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84207795
108FOXP3_21729870_ChIP-Seq_TREG_Human0.83898707
109TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.83303585
110ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.82397312
111P68_20966046_ChIP-Seq_HELA_Human0.81883306
112RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.81383902
113FLI1_27457419_Chip-Seq_LIVER_Mouse0.81006639
114CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79967408
115ERG_20517297_ChIP-Seq_VCAP_Human0.79043970
116SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.78812638
117CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78292381
118CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.78080927
119BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77070694
120GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76920057
121NCOR1_26117541_ChIP-Seq_K562_Human0.76536787
122CTCF_21964334_Chip-Seq_Bcells_Human0.76272439
123PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76060582
124GATA3_26560356_Chip-Seq_TH1_Human0.75800578
125TAF2_19829295_ChIP-Seq_ESCs_Human0.75706366
126SA1_27219007_Chip-Seq_Bcells_Human0.74859384
127GATA2_19941826_ChIP-Seq_K562_Human0.74842971
128MYC_18358816_ChIP-ChIP_MESCs_Mouse0.74065214
129E2F1_20622854_ChIP-Seq_HELA_Human0.74042986
130PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.73441989
131GATA3_21867929_ChIP-Seq_TH1_Mouse0.71548558
132EST1_17652178_ChIP-ChIP_JURKAT_Human0.70867878
133FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.70453509
134FOXM1_23109430_ChIP-Seq_U2OS_Human0.69425815
135GATA1_22383799_ChIP-Seq_G1ME_Mouse0.66824776
136GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.66141692
137ETS1_21867929_ChIP-Seq_TH2_Mouse0.65808874
138FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65729314
139SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.65162059
140EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.64069554
141CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.63491138

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.73740228
2MP0005671_abnormal_response_to5.28678203
3MP0000685_abnormal_immune_system3.77934950
4MP0006054_spinal_hemorrhage3.69350970
5MP0009333_abnormal_splenocyte_physiolog3.31599821
6MP0001873_stomach_inflammation3.15365219
7MP0002166_altered_tumor_susceptibility3.13830200
8MP0001835_abnormal_antigen_presentation3.00800245
9MP0001800_abnormal_humoral_immune2.97074179
10MP0002398_abnormal_bone_marrow2.87833656
11MP0000703_abnormal_thymus_morphology2.83834645
12MP0005000_abnormal_immune_tolerance2.74969603
13MP0002420_abnormal_adaptive_immunity2.74261787
14MP0001819_abnormal_immune_cell2.69344209
15MP0000569_abnormal_digit_pigmentation2.68174326
16MP0009785_altered_susceptibility_to2.55701191
17MP0002723_abnormal_immune_serum2.54471775
18MP0002006_tumorigenesis2.41501788
19MP0000716_abnormal_immune_system2.39052081
20MP0005025_abnormal_response_to2.37612570
21MP0002722_abnormal_immune_system2.35339669
22MP0002405_respiratory_system_inflammati2.34533125
23MP0002452_abnormal_antigen_presenting2.33485068
24MP0003300_gastrointestinal_ulcer2.28649794
25MP0005387_immune_system_phenotype2.26540334
26MP0001790_abnormal_immune_system2.26540334
27MP0000689_abnormal_spleen_morphology2.20335938
28MP0010352_gastrointestinal_tract_polyps2.14840096
29MP0002933_joint_inflammation2.12180576
30MP0004147_increased_porphyrin_level2.12057551
31MP0006082_CNS_inflammation1.91779337
32MP0002429_abnormal_blood_cell1.91342188
33MP0002396_abnormal_hematopoietic_system1.88663247
34MP0002148_abnormal_hypersensitivity_rea1.87393468
35MP0000858_altered_metastatic_potential1.84808048
36MP0002138_abnormal_hepatobiliary_system1.78305838
37MP0005464_abnormal_platelet_physiology1.77734323
38MP0010155_abnormal_intestine_physiology1.77523981
39MP0002419_abnormal_innate_immunity1.77521812
40MP0004947_skin_inflammation1.77170672
41MP0005623_abnormal_meninges_morphology1.73402920
42MP0005645_abnormal_hypothalamus_physiol1.68653687
43MP0000372_irregular_coat_pigmentation1.68169530
44MP0003436_decreased_susceptibility_to1.67736783
45MP0001845_abnormal_inflammatory_respons1.66676115
46MP0003866_abnormal_defecation1.57784560
47MP0009697_abnormal_copulation1.45737145
48MP0003724_increased_susceptibility_to1.45448368
49MP0004381_abnormal_hair_follicle1.39248110
50MP0003448_altered_tumor_morphology1.32034131
51MP0005360_urolithiasis1.31927119
52MP0003045_fibrosis1.30929813
53MP0002877_abnormal_melanocyte_morpholog1.28393612
54MP0001529_abnormal_vocalization1.24988855
55MP0005174_abnormal_tail_pigmentation1.22812724
56MP0001905_abnormal_dopamine_level1.22453263
57MP0003646_muscle_fatigue1.20222598
58MP0004808_abnormal_hematopoietic_stem1.18236422
59MP0003183_abnormal_peptide_metabolism1.14394011
60MP0000465_gastrointestinal_hemorrhage1.13731754
61MP0002009_preneoplasia1.10950370
62MP0002019_abnormal_tumor_incidence1.09968386
63MP0003787_abnormal_imprinting1.07266196
64MP0004957_abnormal_blastocyst_morpholog1.04418943
65MP0003303_peritoneal_inflammation1.04184765
66MP0002163_abnormal_gland_morphology1.02932346
67MP0005379_endocrine/exocrine_gland_phen1.00661174
68MP0003075_altered_response_to0.95154515
69MP0003252_abnormal_bile_duct0.94728577
70MP0008469_abnormal_protein_level0.94288977
71MP0001853_heart_inflammation0.94119356
72MP0004145_abnormal_muscle_electrophysio0.92953235
73MP0002693_abnormal_pancreas_physiology0.92439361
74MP0003453_abnormal_keratinocyte_physiol0.91475234
75MP0003279_aneurysm0.91472331
76MP0005023_abnormal_wound_healing0.90445344
77MP0009643_abnormal_urine_homeostasis0.88605236
78MP0003880_abnormal_central_pattern0.87235772
79MP0005084_abnormal_gallbladder_morpholo0.86744415
80MP0001851_eye_inflammation0.86657904
81MP0003011_delayed_dark_adaptation0.85862143
82MP0006292_abnormal_olfactory_placode0.85132020
83MP0003705_abnormal_hypodermis_morpholog0.85005450
84MP0005646_abnormal_pituitary_gland0.81701507
85MP0009379_abnormal_foot_pigmentation0.81186342
86MP0000920_abnormal_myelination0.80703072
87MP0001968_abnormal_touch/_nociception0.80187406
88MP0005075_abnormal_melanosome_morpholog0.79481048
89MP0002132_abnormal_respiratory_system0.78921994
90MP0001545_abnormal_hematopoietic_system0.76888418
91MP0005397_hematopoietic_system_phenotyp0.76888418
92MP0008873_increased_physiological_sensi0.75067346
93MP0001533_abnormal_skeleton_physiology0.73471934
94MP0003890_abnormal_embryonic-extraembry0.73399925
95MP0000015_abnormal_ear_pigmentation0.71396473
96MP0002638_abnormal_pupillary_reflex0.70924447
97MP0003172_abnormal_lysosome_physiology0.70778318
98MP0002837_dystrophic_cardiac_calcinosis0.69868722
99MP0002822_catalepsy0.69334494
100MP0008057_abnormal_DNA_replication0.69264311
101MP0002095_abnormal_skin_pigmentation0.69133416
102MP0008872_abnormal_physiological_respon0.68419011
103MP0008058_abnormal_DNA_repair0.67382937
104MP0004510_myositis0.66702456
105MP0001348_abnormal_lacrimal_gland0.66244933
106MP0001661_extended_life_span0.66136572
107MP0002277_abnormal_respiratory_mucosa0.65792853
108MP0003786_premature_aging0.64956888
109MP0001188_hyperpigmentation0.64493496
110MP0005166_decreased_susceptibility_to0.62344781
111MP0001191_abnormal_skin_condition0.60595219
112MP0000490_abnormal_crypts_of0.60259477
113MP0008961_abnormal_basal_metabolism0.58700118
114MP0003091_abnormal_cell_migration0.58323215
115MP0003077_abnormal_cell_cycle0.58042230
116MP0002998_abnormal_bone_remodeling0.57137387
117MP0002653_abnormal_ependyma_morphology0.56912777
118MP0001663_abnormal_digestive_system0.56813680
119MP0009278_abnormal_bone_marrow0.55445843
120MP0003638_abnormal_response/metabolism_0.54611302
121MP0001243_abnormal_dermal_layer0.54445964
122MP0009763_increased_sensitivity_to0.53991135
123MP0003795_abnormal_bone_structure0.53838745
124MP0005408_hypopigmentation0.53777770
125MP0005310_abnormal_salivary_gland0.52905654
126MP0004883_abnormal_blood_vessel0.51597497
127MP0002136_abnormal_kidney_physiology0.51096163
128MP0000609_abnormal_liver_physiology0.48894993
129MP0009765_abnormal_xenobiotic_induced0.48194206
130MP0008569_lethality_at_weaning0.47327563
131MP0003693_abnormal_embryo_hatching0.46614423
132MP0010094_abnormal_chromosome_stability0.45666086
133MP0005076_abnormal_cell_differentiation0.45655201
134MP0000477_abnormal_intestine_morphology0.44314037
135MP0003959_abnormal_lean_body0.44080318
136MP0009764_decreased_sensitivity_to0.43613230
137MP0000367_abnormal_coat/_hair0.43130339
138MP0000249_abnormal_blood_vessel0.42049010
139MP0001764_abnormal_homeostasis0.41718839
140MP0004185_abnormal_adipocyte_glucose0.40735347

Predicted human phenotypes

RankGene SetZ-score
1Myositis (HP:0100614)7.84878753
2T lymphocytopenia (HP:0005403)7.57020259
3Abnormality of T cell number (HP:0011839)7.25291088
4Optic neuritis (HP:0100653)5.27242624
5Retrobulbar optic neuritis (HP:0100654)5.27242624
6Keratoconjunctivitis sicca (HP:0001097)5.14722554
7Elevated erythrocyte sedimentation rate (HP:0003565)4.89779626
8Agammaglobulinemia (HP:0004432)4.72753147
9Orchitis (HP:0100796)4.65641716
10Keratoconjunctivitis (HP:0001096)4.64042070
11Aplastic anemia (HP:0001915)4.62370216
12Increased IgM level (HP:0003496)4.50694010
13Pustule (HP:0200039)4.46272351
14Severe combined immunodeficiency (HP:0004430)4.30051177
15Encephalitis (HP:0002383)4.27634071
16Abnormality of T cells (HP:0002843)4.20005448
17Combined immunodeficiency (HP:0005387)4.13839128
18Chronic otitis media (HP:0000389)3.88575474
19Abnormal delayed hypersensitivity skin test (HP:0002963)3.85368475
20Recurrent abscess formation (HP:0002722)3.80027500
21IgG deficiency (HP:0004315)3.75876786
22Spontaneous hematomas (HP:0007420)3.74730133
23Joint swelling (HP:0001386)3.74083173
24Recurrent viral infections (HP:0004429)3.61026785
25Eosinophilia (HP:0001880)3.56160336
26Chronic obstructive pulmonary disease (HP:0006510)3.53826306
27Obstructive lung disease (HP:0006536)3.53826306
28Stomatitis (HP:0010280)3.52932871
29Abnormality of eosinophils (HP:0001879)3.40595947
30Abnormal platelet volume (HP:0011876)3.32238752
31Reduced antithrombin III activity (HP:0001976)3.25690362
32Recurrent bacterial skin infections (HP:0005406)3.19108525
33Autoimmune thrombocytopenia (HP:0001973)3.15682448
34Nasal polyposis (HP:0100582)3.14520202
35Thyroiditis (HP:0100646)3.13889135
36Leukocytosis (HP:0001974)3.12419240
37Spondylolisthesis (HP:0003302)3.11609947
38Increased mean platelet volume (HP:0011877)3.11475759
39Recurrent cutaneous fungal infections (HP:0011370)3.07459884
40Chronic mucocutaneous candidiasis (HP:0002728)3.07459884
41Pulmonary embolism (HP:0002204)3.06743250
42Abnormality of T cell physiology (HP:0011840)3.03551260
43Thrombocytosis (HP:0001894)2.99332450
44Arterial thrombosis (HP:0004420)2.95772249
45Abnormality of macular pigmentation (HP:0008002)2.94157127
4611 pairs of ribs (HP:0000878)2.92983536
47Colon cancer (HP:0003003)2.92510036
48Hemoptysis (HP:0002105)2.87757034
49Granulocytopenia (HP:0001913)2.87426013
50Hypoproteinemia (HP:0003075)2.86949681
51Panhypogammaglobulinemia (HP:0003139)2.86179774
52Meningitis (HP:0001287)2.83536688
53Arterial tortuosity (HP:0005116)2.78894104
54Recurrent bronchitis (HP:0002837)2.76352963
55Absent rod-and cone-mediated responses on ERG (HP:0007688)2.74159882
56Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.74121035
57Abnormality of the prostate (HP:0008775)2.73156631
58Abnormality of B cell number (HP:0010975)2.73145850
59B lymphocytopenia (HP:0010976)2.73145850
60Mediastinal lymphadenopathy (HP:0100721)2.73114015
61Birth length less than 3rd percentile (HP:0003561)2.72993003
62Recurrent fungal infections (HP:0002841)2.67060853
63Abnormality of the nasal mucosa (HP:0000433)2.58695010
64Central scotoma (HP:0000603)2.49058514
65Hypergammaglobulinemia (HP:0010702)2.47839921
66Abnormal rod and cone electroretinograms (HP:0008323)2.47310409
67Dyschromatopsia (HP:0007641)2.46083973
68Dry hair (HP:0011359)2.45843313
69Aplasia/Hypoplasia of the thymus (HP:0010515)2.45342325
70Autoimmune hemolytic anemia (HP:0001890)2.44465787
71Hypoplasia of the thymus (HP:0000778)2.44035168
72IgM deficiency (HP:0002850)2.41719198
73Vascular tortuosity (HP:0004948)2.39930739
74Chest pain (HP:0100749)2.38197422
75Long clavicles (HP:0000890)2.37124646
76Eczematoid dermatitis (HP:0000976)2.36752792
77Aortic aneurysm (HP:0004942)2.35863494
78Mitochondrial inheritance (HP:0001427)2.35702938
79Pancreatic islet-cell hyperplasia (HP:0004510)2.33158569
80Pulmonary infiltrates (HP:0002113)2.32655096
81Lymphopenia (HP:0001888)2.31686419
82Visual hallucinations (HP:0002367)2.31120401
83Dicarboxylic aciduria (HP:0003215)2.31018867
84Abnormality of dicarboxylic acid metabolism (HP:0010995)2.31018867
85Delayed closure of the anterior fontanelle (HP:0001476)2.30050923
86Short 4th metacarpal (HP:0010044)2.29354976
87Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.29354976
88Epistaxis (HP:0000421)2.28002304
89Striae distensae (HP:0001065)2.27489620
90Petechiae (HP:0000967)2.27173785
91Inflammation of the large intestine (HP:0002037)2.27019180
92Hematochezia (HP:0002573)2.26916233
93Abnormal protein glycosylation (HP:0012346)2.24007142
94Abnormal glycosylation (HP:0012345)2.24007142
95Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.24007142
96Abnormal protein N-linked glycosylation (HP:0012347)2.24007142
97Recurrent sinusitis (HP:0011108)2.23902785
98Increased IgE level (HP:0003212)2.23468180
99Microcytic anemia (HP:0001935)2.20668815
100Abnormality of cells of the lymphoid lineage (HP:0012140)2.20607528
101Abnormality of the pleura (HP:0002103)2.18986561
102Nonimmune hydrops fetalis (HP:0001790)2.18710887
103Increased intramyocellular lipid droplets (HP:0012240)2.18632182
104Gangrene (HP:0100758)2.18549897
105Recurrent gram-negative bacterial infections (HP:0005420)2.18467334
106Keratitis (HP:0000491)2.18238324
107Acute hepatic failure (HP:0006554)2.16284018
108Skin rash (HP:0000988)2.16191135
109Hepatocellular necrosis (HP:0001404)2.16025348
110Thoracolumbar scoliosis (HP:0002944)2.15563086
111Biliary tract neoplasm (HP:0100574)2.14940622
112Recurrent skin infections (HP:0001581)2.14531589
113Lymphoma (HP:0002665)2.14157963
114Vasculitis (HP:0002633)2.13810260
115Neoplasm of the small intestine (HP:0100833)2.13267731
116Toxemia of pregnancy (HP:0100603)2.12598369
117Gastrointestinal inflammation (HP:0004386)2.12502954
118Prolonged bleeding time (HP:0003010)2.12134722
119Aortic dissection (HP:0002647)2.11432073
120Chronic sinusitis (HP:0011109)2.10616338
121Abnormal hair whorl (HP:0010721)2.07070608
122Gastrointestinal infarctions (HP:0005244)2.05856676
123Abnormality of macrophages (HP:0004311)2.05562744
124Aseptic necrosis (HP:0010885)2.02935246
125Rectal prolapse (HP:0002035)2.02623660
126Abnormality of the fingertips (HP:0001211)2.01305704
127Abnormality of the columella (HP:0009929)2.01060340
128J-shaped sella turcica (HP:0002680)2.00108580
129Recurrent otitis media (HP:0000403)2.00076484
1303-Methylglutaconic aciduria (HP:0003535)1.99235714
131Focal motor seizures (HP:0011153)1.98713482
132Thoracic kyphosis (HP:0002942)1.98345298
133Chronic diarrhea (HP:0002028)1.95165677
134Severe visual impairment (HP:0001141)1.94349566
135Type I transferrin isoform profile (HP:0003642)1.94206519
136Sepsis (HP:0100806)1.93620277
137Abolished electroretinogram (ERG) (HP:0000550)1.93135366
138Mesomelia (HP:0003027)1.90996970
139Glomerulopathy (HP:0100820)1.90838421
140Papilloma (HP:0012740)1.90659810
141Verrucae (HP:0200043)1.90659810
142Fatigue (HP:0012378)1.90459505
143Palpebral edema (HP:0100540)1.89788870
144Bronchitis (HP:0012387)1.89684829
145Thrombophlebitis (HP:0004418)1.87580320
146Cellular immunodeficiency (HP:0005374)1.87233598
147Urticaria (HP:0001025)1.86519064
148Broad face (HP:0000283)1.85650131
149Cerebral palsy (HP:0100021)1.85007998
150Abnormality of the lumbar spine (HP:0100712)1.84326068
151Abnormal foot bone ossification (HP:0010675)1.83481870
152Hepatic necrosis (HP:0002605)1.83288466
153Abnormality of the pericardium (HP:0001697)1.82055046
154Increased muscle lipid content (HP:0009058)1.80031175
155Abnormality of the thymus (HP:0000777)1.78727763

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.75835912
2MAP4K14.69214168
3CDK84.28679469
4ITK3.73638772
5VRK23.59024058
6NLK3.55731931
7CLK13.02449178
8MELK3.01669483
9ZAP702.89966995
10BCKDK2.83685982
11MAP3K142.78872001
12MAP2K62.78427860
13ZAK2.75520577
14NME22.66137160
15MST42.49232358
16JAK32.38770943
17SCYL22.36783257
18TESK12.31823633
19VRK12.29879635
20PRPF4B2.21738748
21STK102.19227237
22ACVR1B2.01797792
23TLK11.95033597
24LCK1.86911850
25GRK61.85992290
26GRK71.81700153
27PRKCH1.80438755
28ADRBK21.78443393
29MAP3K71.75391558
30FGFR41.73761235
31TAOK31.69642274
32DAPK11.62144274
33BLK1.57109612
34CSK1.54350152
35LIMK11.53889725
36TYK21.51410708
37CDK91.50586098
38SIK31.48305084
39EPHA31.45772771
40SYK1.45296170
41IKBKE1.37917769
42DAPK21.30851991
43HCK1.21828913
44CDK41.20280707
45MAP4K21.19154211
46CDK191.18876389
47TEC1.17682342
48NUAK11.15890571
49FGFR31.15324036
50EIF2AK31.12849422
51MARK31.09947397
52JAK11.05462767
53RPS6KA51.03119292
54BTK1.02047831
55MATK0.99653058
56TBK10.97564535
57BRSK10.96116993
58BRSK20.92136761
59LRRK20.91250949
60GRK10.85918407
61MAP3K110.85703742
62PRKCQ0.84321642
63PIM10.80016885
64PIM20.77822249
65PIK3CG0.77092406
66MAP3K50.76640021
67PKN20.74850979
68DAPK30.74385359
69MAP3K130.73503069
70TRPM70.70381989
71FLT30.68612149
72TAF10.68447231
73PDK20.66297312
74GRK50.64585927
75KDR0.64448878
76IRAK20.64389196
77SIK20.63927978
78FES0.63925683
79EEF2K0.62850317
80MAP3K120.61936260
81TIE10.60942620
82BMPR20.60564394
83LYN0.60166756
84KSR10.58145993
85MAPKAPK50.58055419
86WEE10.54727800
87PDGFRB0.53195390
88JAK20.50704470
89FGFR20.48672496
90ERN10.47987215
91PRKG20.47683684
92SGK30.45540526
93MAP3K100.44335492
94ROCK10.43589877
95RAF10.42422158
96SIK10.42214343
97MARK20.41012998
98IKBKB0.40972123
99AURKA0.40035755
100BCR0.39838645
101RPS6KC10.37919494
102RPS6KL10.37919494
103TNK20.37476298
104SMG10.37098298
105MAPK70.36458738
106FYN0.35935524
107DYRK20.35882433
108ALK0.35175494
109RPS6KA60.34729664
110STK110.33793025
111ATR0.33379259
112PINK10.32110346
113CSF1R0.31574206
114IGF1R0.31448182
115MYLK0.31427041
116INSR0.30603553
117PAK30.30192677
118RIPK40.29857450
119INSRR0.28751651
120CDC70.28324028
121KIT0.27258433
122PRKCA0.26590079
123PAK40.26099042
124TYRO30.25956222
125PASK0.25269096
126MAPKAPK30.24714943
127MAPK110.24595337
128ADRBK10.23580987
129CSNK1G10.23459762
130CSNK1G30.23380790
131RPS6KA40.23307998
132EPHB10.23305325
133CCNB10.22221958
134TTN0.22203625
135IRAK40.21615367
136TGFBR20.21269323
137PRKCD0.20717277
138PDK10.20431644
139PAK10.20068370
140MAPK130.19659024
141CDK60.18818104
142MAP2K20.18439571
143MAPK30.18202173
144ABL10.17825027
145HIPK20.17809714
146KSR20.17471386
147TESK20.17233886
148STK40.16494695
149TRIB30.15055063
150FGFR10.14750411

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053325.70099398
2Primary immunodeficiency_Homo sapiens_hsa053405.43248080
3T cell receptor signaling pathway_Homo sapiens_hsa046604.30964221
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.84544752
5Antigen processing and presentation_Homo sapiens_hsa046123.75630260
6Intestinal immune network for IgA production_Homo sapiens_hsa046723.22171017
7Allograft rejection_Homo sapiens_hsa053303.03146566
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.79573202
9Hematopoietic cell lineage_Homo sapiens_hsa046402.62160522
10Measles_Homo sapiens_hsa051622.47126416
11Type I diabetes mellitus_Homo sapiens_hsa049402.15962248
12Viral myocarditis_Homo sapiens_hsa054162.12069471
13Autoimmune thyroid disease_Homo sapiens_hsa053202.01128855
14Parkinsons disease_Homo sapiens_hsa050121.96069044
15Oxidative phosphorylation_Homo sapiens_hsa001901.89913292
16Leishmaniasis_Homo sapiens_hsa051401.78196787
17Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.69307036
18Leukocyte transendothelial migration_Homo sapiens_hsa046701.68978927
19Colorectal cancer_Homo sapiens_hsa052101.66201829
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61299860
21Ribosome_Homo sapiens_hsa030101.53399955
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.50393925
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.40648002
24Hepatitis B_Homo sapiens_hsa051611.34371019
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.30656366
26Jak-STAT signaling pathway_Homo sapiens_hsa046301.27261963
27Chemokine signaling pathway_Homo sapiens_hsa040621.26585831
28Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.24034099
29Homologous recombination_Homo sapiens_hsa034401.16058942
30Alzheimers disease_Homo sapiens_hsa050101.14281183
31Pancreatic cancer_Homo sapiens_hsa052121.13511571
32Herpes simplex infection_Homo sapiens_hsa051681.12101130
33Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.10039419
34Proteasome_Homo sapiens_hsa030501.07649820
35Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.07628774
36Systemic lupus erythematosus_Homo sapiens_hsa053221.06754960
37Osteoclast differentiation_Homo sapiens_hsa043801.05937699
38Staphylococcus aureus infection_Homo sapiens_hsa051501.01587499
39Caffeine metabolism_Homo sapiens_hsa002320.98657247
40NOD-like receptor signaling pathway_Homo sapiens_hsa046210.97205233
41Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.96943079
42Huntingtons disease_Homo sapiens_hsa050160.94192760
43HTLV-I infection_Homo sapiens_hsa051660.93574448
44Base excision repair_Homo sapiens_hsa034100.91840242
45RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.91754773
46Steroid hormone biosynthesis_Homo sapiens_hsa001400.90207580
47Regulation of autophagy_Homo sapiens_hsa041400.88723257
48B cell receptor signaling pathway_Homo sapiens_hsa046620.87963520
49Nucleotide excision repair_Homo sapiens_hsa034200.87135296
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.86770274
51Phototransduction_Homo sapiens_hsa047440.84506463
52Platelet activation_Homo sapiens_hsa046110.83219172
53Spliceosome_Homo sapiens_hsa030400.82844515
54Acute myeloid leukemia_Homo sapiens_hsa052210.80100178
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77195339
56Chronic myeloid leukemia_Homo sapiens_hsa052200.74674095
57Non-homologous end-joining_Homo sapiens_hsa034500.73136230
58Adherens junction_Homo sapiens_hsa045200.72261483
59RNA polymerase_Homo sapiens_hsa030200.71692975
60Influenza A_Homo sapiens_hsa051640.71630054
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.68950783
62Protein export_Homo sapiens_hsa030600.66511567
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65551010
64Shigellosis_Homo sapiens_hsa051310.64949883
65Cardiac muscle contraction_Homo sapiens_hsa042600.62846694
66DNA replication_Homo sapiens_hsa030300.61675655
67Prion diseases_Homo sapiens_hsa050200.59082958
68Rheumatoid arthritis_Homo sapiens_hsa053230.58278457
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57556077
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56661877
71Mismatch repair_Homo sapiens_hsa034300.56337512
72Fanconi anemia pathway_Homo sapiens_hsa034600.55924835
73Pentose and glucuronate interconversions_Homo sapiens_hsa000400.54328311
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51294854
75Apoptosis_Homo sapiens_hsa042100.50613927
76Pertussis_Homo sapiens_hsa051330.50424824
77Retinol metabolism_Homo sapiens_hsa008300.49948717
78Chemical carcinogenesis_Homo sapiens_hsa052040.49581478
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.49174821
80Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48725826
81Toxoplasmosis_Homo sapiens_hsa051450.48602867
82Epstein-Barr virus infection_Homo sapiens_hsa051690.48522335
83Viral carcinogenesis_Homo sapiens_hsa052030.47831792
84TNF signaling pathway_Homo sapiens_hsa046680.46375063
85Fatty acid elongation_Homo sapiens_hsa000620.44832170
86Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.44014014
87Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42626055
88Salmonella infection_Homo sapiens_hsa051320.42495265
89Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.41252176
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.41047773
91Basal transcription factors_Homo sapiens_hsa030220.40891324
92African trypanosomiasis_Homo sapiens_hsa051430.40438923
93Cell cycle_Homo sapiens_hsa041100.40287002
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39903505
95Long-term potentiation_Homo sapiens_hsa047200.39805758
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39467174
97Malaria_Homo sapiens_hsa051440.39212362
98Pyrimidine metabolism_Homo sapiens_hsa002400.37997184
99Purine metabolism_Homo sapiens_hsa002300.36866833
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.36014746
101Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35953688
102Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.34327766
103Glycosaminoglycan degradation_Homo sapiens_hsa005310.33880462
104Rap1 signaling pathway_Homo sapiens_hsa040150.33858811
105N-Glycan biosynthesis_Homo sapiens_hsa005100.33256560
106Hepatitis C_Homo sapiens_hsa051600.32461984
107Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.32114521
108One carbon pool by folate_Homo sapiens_hsa006700.31448269
109Butanoate metabolism_Homo sapiens_hsa006500.31347913
110Thyroid cancer_Homo sapiens_hsa052160.30881598
111Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.30735930
112Legionellosis_Homo sapiens_hsa051340.30178967
113Olfactory transduction_Homo sapiens_hsa047400.29884079
114Tuberculosis_Homo sapiens_hsa051520.29765491
115RNA degradation_Homo sapiens_hsa030180.28630915
116Renal cell carcinoma_Homo sapiens_hsa052110.25161105
117alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.23633849
118Prostate cancer_Homo sapiens_hsa052150.23526136
119VEGF signaling pathway_Homo sapiens_hsa043700.23424376
120Sulfur metabolism_Homo sapiens_hsa009200.23331704
121FoxO signaling pathway_Homo sapiens_hsa040680.23308905
122Ether lipid metabolism_Homo sapiens_hsa005650.23016569
123Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.22078120
124Endometrial cancer_Homo sapiens_hsa052130.22062101
125Endocytosis_Homo sapiens_hsa041440.21211418
126Asthma_Homo sapiens_hsa053100.20291328
127Toll-like receptor signaling pathway_Homo sapiens_hsa046200.19922575
128Phosphatidylinositol signaling system_Homo sapiens_hsa040700.15812883
129Cyanoamino acid metabolism_Homo sapiens_hsa004600.15421694
130Peroxisome_Homo sapiens_hsa041460.14819887
131Non-small cell lung cancer_Homo sapiens_hsa052230.14536288
132Transcriptional misregulation in cancer_Homo sapiens_hsa052020.14374945
133Pancreatic secretion_Homo sapiens_hsa049720.14158208
134Glucagon signaling pathway_Homo sapiens_hsa049220.13940620
135Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.13004373
136mRNA surveillance pathway_Homo sapiens_hsa030150.11307459
137Small cell lung cancer_Homo sapiens_hsa052220.10757330
138Selenocompound metabolism_Homo sapiens_hsa004500.10453938
139Salivary secretion_Homo sapiens_hsa049700.09009819
140Renin secretion_Homo sapiens_hsa049240.08092095
141Focal adhesion_Homo sapiens_hsa045100.05883227

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