TRBJ2-5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine metabolic process (GO:0046087)7.83666576
2cytidine catabolic process (GO:0006216)7.83666576
3cytidine deamination (GO:0009972)7.83666576
4pyrimidine ribonucleoside catabolic process (GO:0046133)7.19583740
5DNA deamination (GO:0045006)6.87130551
6positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.85414370
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.07814748
8positive thymic T cell selection (GO:0045059)5.71366748
9T cell migration (GO:0072678)5.60760466
10positive T cell selection (GO:0043368)5.56259635
11positive regulation of calcium-mediated signaling (GO:0050850)5.34797400
12negative T cell selection (GO:0043383)5.23768751
13cellular response to interleukin-15 (GO:0071350)5.22002355
14positive regulation of B cell differentiation (GO:0045579)4.52906849
15deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.51696463
16pyrimidine nucleoside catabolic process (GO:0046135)4.42002115
17thymic T cell selection (GO:0045061)4.40493626
18negative thymic T cell selection (GO:0045060)4.33483937
19regulation of T cell receptor signaling pathway (GO:0050856)4.29474387
20response to interleukin-15 (GO:0070672)4.27758545
21regulation of B cell receptor signaling pathway (GO:0050855)4.17463204
22regulation of calcium-mediated signaling (GO:0050848)4.12217084
23purine deoxyribonucleotide catabolic process (GO:0009155)4.11204176
24regulation of alpha-beta T cell proliferation (GO:0046640)4.10403557
25regulation of B cell differentiation (GO:0045577)4.10007304
26T cell selection (GO:0045058)4.07202130
27regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.06623962
28negative regulation of B cell apoptotic process (GO:0002903)4.04412261
29purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.97822888
30positive regulation of gamma-delta T cell activation (GO:0046645)3.95569158
31regulation of regulatory T cell differentiation (GO:0045589)3.92838408
32eosinophil chemotaxis (GO:0048245)3.92212317
33negative regulation of T cell apoptotic process (GO:0070233)3.87882497
34negative regulation by host of viral transcription (GO:0043922)3.83553670
35lymphocyte chemotaxis (GO:0048247)3.72069595
36Arp2/3 complex-mediated actin nucleation (GO:0034314)3.64904608
37positive regulation of interleukin-8 secretion (GO:2000484)3.63752934
38macrophage chemotaxis (GO:0048246)3.59205810
39negative regulation of viral genome replication (GO:0045071)3.55605894
40eosinophil migration (GO:0072677)3.55467290
41purinergic nucleotide receptor signaling pathway (GO:0035590)3.55286457
42positive regulation of natural killer cell mediated immunity (GO:0002717)3.51662220
43regulation of interleukin-12 biosynthetic process (GO:0045075)3.51374728
44positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.49668129
45purine deoxyribonucleotide metabolic process (GO:0009151)3.47165454
46autophagic vacuole fusion (GO:0000046)3.46186110
47T cell costimulation (GO:0031295)3.44195575
48T cell apoptotic process (GO:0070231)3.43576240
49lymphocyte costimulation (GO:0031294)3.39788877
50negative regulation of lymphocyte apoptotic process (GO:0070229)3.39740135
51regulation of lymphocyte chemotaxis (GO:1901623)3.38522321
52antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.36888495
53deoxyribonucleotide catabolic process (GO:0009264)3.35279682
54negative regulation of B cell proliferation (GO:0030889)3.33409617
55leukocyte aggregation (GO:0070486)3.32749332
56cytolysis (GO:0019835)3.32235396
57Peyers patch development (GO:0048541)3.30866367
58mucosal-associated lymphoid tissue development (GO:0048537)3.30866367
59positive regulation of defense response to virus by host (GO:0002230)3.30728446
60deoxyribose phosphate catabolic process (GO:0046386)3.29425311
61positive regulation of lymphocyte migration (GO:2000403)3.25010791
62B cell receptor signaling pathway (GO:0050853)3.24689725
63positive regulation of monocyte chemotaxis (GO:0090026)3.22891693
64deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.20515330
65regulation of T cell tolerance induction (GO:0002664)3.19186147
66negative regulation of thymocyte apoptotic process (GO:0070244)3.18299076
67positive regulation of alpha-beta T cell proliferation (GO:0046641)3.16832613
68actin nucleation (GO:0045010)3.15318375
69negative regulation of nitric-oxide synthase activity (GO:0051001)3.14782317
70lymphocyte migration (GO:0072676)3.14152997
71regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.13306431
72regulation of natural killer cell mediated immunity (GO:0002715)3.13306431
73antigen processing and presentation of endogenous antigen (GO:0019883)3.12650006
74mannosylation (GO:0097502)3.12591924
75antigen receptor-mediated signaling pathway (GO:0050851)3.11542750
76regulation of viral genome replication (GO:0045069)3.11190373
77regulation of gamma-delta T cell differentiation (GO:0045586)3.07205928
78regulation of activation of Janus kinase activity (GO:0010533)3.06795228
79DNA dealkylation (GO:0035510)3.03935201
80negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.01590721
81negative regulation of viral transcription (GO:0032897)3.00452446
82positive regulation of T cell differentiation in thymus (GO:0033089)3.00104211
83T cell receptor signaling pathway (GO:0050852)3.00057709
84negative regulation of B cell activation (GO:0050869)2.99444031
85positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.97897400
86regulation of interleukin-2 biosynthetic process (GO:0045076)2.97640777
87positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.92986736
88positive regulation of tolerance induction (GO:0002645)2.92573252
89purine nucleotide salvage (GO:0032261)2.91985490
90response to interferon-beta (GO:0035456)2.91496383
91G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.90571773
92regulation of T cell apoptotic process (GO:0070232)2.82957887
93DNA demethylation (GO:0080111)2.82452167
94protoporphyrinogen IX biosynthetic process (GO:0006782)2.81651959
95regulation of B cell apoptotic process (GO:0002902)2.79693568
96regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.78220965
97interferon-gamma production (GO:0032609)2.78039009
98pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.77852061
99T cell mediated immunity (GO:0002456)2.76431990
100organelle membrane fusion (GO:0090174)2.75878175

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.26055072
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.65723689
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.44018734
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.57157279
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.52082341
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.13452552
7MYB_26560356_Chip-Seq_TH2_Human3.00161822
8ELF1_17652178_ChIP-ChIP_JURKAT_Human2.93464255
9RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.73841827
10IRF8_21731497_ChIP-ChIP_J774_Mouse2.71157402
11LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.64309427
12UTX_26944678_Chip-Seq_JUKART_Human2.46434737
13RUNX_20019798_ChIP-Seq_JUKART_Human2.45502924
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.32449691
15MYB_26560356_Chip-Seq_TH1_Human2.32390792
16GATA3_27048872_Chip-Seq_THYMUS_Human2.23107736
17STAT4_19710469_ChIP-ChIP_TH1__Mouse2.16610807
18MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.11739059
19BP1_19119308_ChIP-ChIP_Hs578T_Human10.5413870
20FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.99258008
21SPI1_23547873_ChIP-Seq_NB4_Human1.85162968
22GATA3_26560356_Chip-Seq_TH2_Human1.80426745
23SCL_19346495_ChIP-Seq_HPC-7_Human1.77845332
24MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.74567808
25E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.68383941
26MAF_26560356_Chip-Seq_TH2_Human1.68069378
27STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.66860798
28MAF_26560356_Chip-Seq_TH1_Human1.65015966
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.58085402
30LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.56839837
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54952447
32FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.54514605
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.52216129
34IRF8_27001747_Chip-Seq_BMDM_Mouse1.52041163
35HTT_18923047_ChIP-ChIP_STHdh_Human1.51550918
36BCL6_27268052_Chip-Seq_Bcells_Human1.48600996
37VDR_23849224_ChIP-Seq_CD4+_Human1.46576428
38JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.44855322
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.42037176
40FOXP3_21729870_ChIP-Seq_TREG_Human1.38350328
41ELF1_20517297_ChIP-Seq_JURKAT_Human1.37787707
42GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.32861986
43RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.26890007
44CIITA_25753668_ChIP-Seq_RAJI_Human1.25798705
45CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.24483570
46P300_27268052_Chip-Seq_Bcells_Human1.20274196
47KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.20158095
48HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.18563227
49VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.15702663
50GABP_17652178_ChIP-ChIP_JURKAT_Human1.14619196
51EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.14373435
52PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.14000838
53TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.09665737
54RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08838000
55RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.05992672
56GATA2_22383799_ChIP-Seq_G1ME_Mouse1.05000852
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.04348430
58CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.03386110
59NANOG_20526341_ChIP-Seq_ESCs_Human1.03306671
60VDR_24763502_ChIP-Seq_THP-1_Human1.03254319
61SPI1_23127762_ChIP-Seq_K562_Human1.02729782
62PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02591297
63CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.99901533
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.99463343
65SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.96584535
66RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96390090
67PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95965846
68MYC_22102868_ChIP-Seq_BL_Human0.95193754
69VDR_24787735_ChIP-Seq_THP-1_Human0.94463431
70FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93798842
71YY1_22570637_ChIP-Seq_MALME-3M_Human0.92734787
72BCOR_27268052_Chip-Seq_Bcells_Human0.92455467
73CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.90860900
74CTCF_20526341_ChIP-Seq_ESCs_Human0.88477203
75ETS1_20019798_ChIP-Seq_JURKAT_Human0.88157576
76RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.87294826
77FOXA1_25329375_ChIP-Seq_VCAP_Human0.87261329
78FOXA1_27270436_Chip-Seq_PROSTATE_Human0.87261329
79P68_20966046_ChIP-Seq_HELA_Human0.87250520
80GATA1_19941826_ChIP-Seq_K562_Human0.84284778
81SRF_21415370_ChIP-Seq_HL-1_Mouse0.84012282
82GATA3_21878914_ChIP-Seq_MCF-7_Human0.83883071
83SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.82633552
84CEBPB_22108803_ChIP-Seq_LS180_Human0.82272941
85CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.81006473
86EGR1_23403033_ChIP-Seq_LIVER_Mouse0.80996849
87HOXB4_20404135_ChIP-ChIP_EML_Mouse0.80736401
88IGF1R_20145208_ChIP-Seq_DFB_Human0.80059592
89CTCF_26484167_Chip-Seq_Bcells_Mouse0.78374561
90FOXH1_21741376_ChIP-Seq_EPCs_Human0.78232883
91PHF8_20622854_ChIP-Seq_HELA_Human0.78161336
92TAF2_19829295_ChIP-Seq_ESCs_Human0.77980889
93ERG_20517297_ChIP-Seq_VCAP_Human0.77823095
94FLI1_27457419_Chip-Seq_LIVER_Mouse0.77604515
95VDR_22108803_ChIP-Seq_LS180_Human0.77511220
96RARB_24833708_ChIP-Seq_LIVER_Mouse0.76577309
97E2F1_20622854_ChIP-Seq_HELA_Human0.75596931
98RAC3_21632823_ChIP-Seq_H3396_Human0.75219104
99ZNF274_21170338_ChIP-Seq_K562_Hela0.75166309
100TP53_22573176_ChIP-Seq_HFKS_Human0.74912996

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.81382227
2MP0009333_abnormal_splenocyte_physiolog3.71559856
3MP0009785_altered_susceptibility_to3.22550068
4MP0003763_abnormal_thymus_physiology3.19250775
5MP0001800_abnormal_humoral_immune3.19082361
6MP0005000_abnormal_immune_tolerance3.11528059
7MP0001835_abnormal_antigen_presentation3.09638699
8MP0002148_abnormal_hypersensitivity_rea2.96191204
9MP0000372_irregular_coat_pigmentation2.85145321
10MP0002723_abnormal_immune_serum2.72054446
11MP0002420_abnormal_adaptive_immunity2.69911321
12MP0001790_abnormal_immune_system2.66450073
13MP0005387_immune_system_phenotype2.66450073
14MP0001819_abnormal_immune_cell2.63271824
15MP0005075_abnormal_melanosome_morpholog2.62210109
16MP0006082_CNS_inflammation2.52810228
17MP0003436_decreased_susceptibility_to2.45408352
18MP0005025_abnormal_response_to2.45075807
19MP0002452_abnormal_antigen_presenting2.42991271
20MP0003866_abnormal_defecation2.38547297
21MP0004147_increased_porphyrin_level2.31308910
22MP0000685_abnormal_immune_system2.27629397
23MP0002398_abnormal_bone_marrow2.27335969
24MP0003787_abnormal_imprinting2.26223317
25MP0003646_muscle_fatigue2.18699273
26MP0003045_fibrosis2.13839410
27MP0000716_abnormal_immune_system2.07484769
28MP0001873_stomach_inflammation2.05925769
29MP0002419_abnormal_innate_immunity1.86622629
30MP0005464_abnormal_platelet_physiology1.77116264
31MP0002405_respiratory_system_inflammati1.76355151
32MP0010155_abnormal_intestine_physiology1.73497255
33MP0005645_abnormal_hypothalamus_physiol1.72894721
34MP0002166_altered_tumor_susceptibility1.66978802
35MP0002429_abnormal_blood_cell1.66237420
36MP0002722_abnormal_immune_system1.62643708
37MP0000689_abnormal_spleen_morphology1.60866662
38MP0005451_abnormal_body_composition1.56374779
39MP0002933_joint_inflammation1.51396900
40MP0009764_decreased_sensitivity_to1.51350332
41MP0000703_abnormal_thymus_morphology1.48556686
42MP0003724_increased_susceptibility_to1.45903317
43MP0003806_abnormal_nucleotide_metabolis1.39606732
44MP0001853_heart_inflammation1.39135728
45MP0001845_abnormal_inflammatory_respons1.37983931
46MP0009765_abnormal_xenobiotic_induced1.32945666
47MP0005310_abnormal_salivary_gland1.31200812
48MP0002006_tumorigenesis1.29699852
49MP0008469_abnormal_protein_level1.27852289
50MP0003448_altered_tumor_morphology1.23426079
51MP0009763_increased_sensitivity_to1.21746268
52MP0008877_abnormal_DNA_methylation1.16637594
53MP0003252_abnormal_bile_duct1.12570356
54MP0001533_abnormal_skeleton_physiology1.11784720
55MP0009697_abnormal_copulation1.10162179
56MP0002277_abnormal_respiratory_mucosa1.07960950
57MP0002019_abnormal_tumor_incidence1.06008330
58MP0002396_abnormal_hematopoietic_system1.02376677
59MP0004947_skin_inflammation0.97273432
60MP0003075_altered_response_to0.94467814
61MP0001905_abnormal_dopamine_level0.92886595
62MP0002163_abnormal_gland_morphology0.91295296
63MP0001968_abnormal_touch/_nociception0.90600269
64MP0004381_abnormal_hair_follicle0.88911963
65MP0002876_abnormal_thyroid_physiology0.86239394
66MP0008872_abnormal_physiological_respon0.85345538
67MP0002009_preneoplasia0.84750565
68MP0009643_abnormal_urine_homeostasis0.84268687
69MP0005166_decreased_susceptibility_to0.82934091
70MP0008873_increased_physiological_sensi0.80849504
71MP0002693_abnormal_pancreas_physiology0.79310905
72MP0005397_hematopoietic_system_phenotyp0.76738357
73MP0001545_abnormal_hematopoietic_system0.76738357
74MP0004145_abnormal_muscle_electrophysio0.76214651
75MP0001764_abnormal_homeostasis0.73365130
76MP0002168_other_aberrant_phenotype0.70735106
77MP0009278_abnormal_bone_marrow0.63991674
78MP0005646_abnormal_pituitary_gland0.63469926
79MP0001919_abnormal_reproductive_system0.61763551
80MP0000371_diluted_coat_color0.61296366
81MP0003880_abnormal_central_pattern0.60117153
82MP0005084_abnormal_gallbladder_morpholo0.59194623
83MP0010386_abnormal_urinary_bladder0.57886529
84MP0005551_abnormal_eye_electrophysiolog0.55937315
85MP0005083_abnormal_biliary_tract0.55423992
86MP0005390_skeleton_phenotype0.53074787
87MP0000470_abnormal_stomach_morphology0.50955026
88MP0003786_premature_aging0.49506578
89MP0000858_altered_metastatic_potential0.48487286
90MP0001501_abnormal_sleep_pattern0.48331879
91MP0005584_abnormal_enzyme/coenzyme_acti0.48329800
92MP0000639_abnormal_adrenal_gland0.48106425
93MP0002095_abnormal_skin_pigmentation0.47733928
94MP0002909_abnormal_adrenal_gland0.46979756
95MP0008004_abnormal_stomach_pH0.46902938
96MP0002138_abnormal_hepatobiliary_system0.45868011
97MP0006292_abnormal_olfactory_placode0.45609386
98MP0006276_abnormal_autonomic_nervous0.45281080
99MP0006036_abnormal_mitochondrial_physio0.44055604
100MP0000569_abnormal_digit_pigmentation0.43913180

Predicted human phenotypes

RankGene SetZ-score
1Severe combined immunodeficiency (HP:0004430)5.99696759
2T lymphocytopenia (HP:0005403)5.94788625
3Abnormality of T cell number (HP:0011839)5.73663141
4Agammaglobulinemia (HP:0004432)5.66668327
5Autoimmune hemolytic anemia (HP:0001890)5.39948481
6Stomatitis (HP:0010280)4.86397901
7Combined immunodeficiency (HP:0005387)4.70649219
8Aplastic anemia (HP:0001915)4.59335920
9Thyroiditis (HP:0100646)4.42804617
10Abnormality of T cells (HP:0002843)4.41261792
11Recurrent fungal infections (HP:0002841)4.37836461
12IgG deficiency (HP:0004315)4.30942980
13Recurrent viral infections (HP:0004429)4.16913489
14Elevated erythrocyte sedimentation rate (HP:0003565)4.01175840
15Increased IgM level (HP:0003496)3.90776727
16Chronic diarrhea (HP:0002028)3.85472128
17Panhypogammaglobulinemia (HP:0003139)3.82203375
18Autoimmune thrombocytopenia (HP:0001973)3.82058036
19Hypoproteinemia (HP:0003075)3.76468358
20Meningitis (HP:0001287)3.74462949
213-Methylglutaconic aciduria (HP:0003535)3.62629523
22B lymphocytopenia (HP:0010976)3.60814326
23IgM deficiency (HP:0002850)3.52377403
24Abnormal delayed hypersensitivity skin test (HP:0002963)3.50086275
25Abnormality of B cell number (HP:0010975)3.47826835
26Chronic mucocutaneous candidiasis (HP:0002728)3.46081323
27Recurrent cutaneous fungal infections (HP:0011370)3.46081323
28Abnormality of eosinophils (HP:0001879)3.39186339
29Abnormality of the prostate (HP:0008775)3.23468278
30Eosinophilia (HP:0001880)3.14687158
31Granulocytopenia (HP:0001913)3.11896999
32Increased IgE level (HP:0003212)3.05090469
33Acute necrotizing encephalopathy (HP:0006965)2.96569185
34Encephalitis (HP:0002383)2.94534880
35Chronic obstructive pulmonary disease (HP:0006510)2.85594428
36Obstructive lung disease (HP:0006536)2.85594428
37Hypoplasia of the thymus (HP:0000778)2.82826484
38Leukocytosis (HP:0001974)2.77502774
39Abnormal mitochondria in muscle tissue (HP:0008316)2.75033478
40Acute hepatic failure (HP:0006554)2.69556867
41Mitochondrial inheritance (HP:0001427)2.63293282
42Abnormality of T cell physiology (HP:0011840)2.63215223
43Mediastinal lymphadenopathy (HP:0100721)2.62107563
44Hypergammaglobulinemia (HP:0010702)2.59992255
45Acute encephalopathy (HP:0006846)2.58912395
46Abnormality of dicarboxylic acid metabolism (HP:0010995)2.57769077
47Dicarboxylic aciduria (HP:0003215)2.57769077
48Recurrent bronchitis (HP:0002837)2.51178044
49Type I transferrin isoform profile (HP:0003642)2.47909610
50Increased intramyocellular lipid droplets (HP:0012240)2.46841502
51Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.46565283
52Lymphopenia (HP:0001888)2.45809965
53Congenital stationary night blindness (HP:0007642)2.45087999
54Abnormality of cells of the lymphoid lineage (HP:0012140)2.42682963
55Progressive macrocephaly (HP:0004481)2.40736085
56Generalized aminoaciduria (HP:0002909)2.37911512
57Abnormality of macrophages (HP:0004311)2.34707330
58Joint swelling (HP:0001386)2.32269341
59Increased muscle lipid content (HP:0009058)2.31853866
60Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.23931551
61Pancytopenia (HP:0001876)2.23639737
62Sepsis (HP:0100806)2.17412797
63Severe visual impairment (HP:0001141)2.15778122
64Skin rash (HP:0000988)2.14499515
65Recurrent skin infections (HP:0001581)2.14325617
66Lymphoma (HP:0002665)2.07408068
67Cerebral edema (HP:0002181)2.03254568
68Renal cortical cysts (HP:0000803)2.01462183
69Increased CSF lactate (HP:0002490)2.01174449
70Abnormality of the heme biosynthetic pathway (HP:0010472)2.00826539
71Neutropenia (HP:0001875)2.00766661
72Cellulitis (HP:0100658)1.97239022
73Abnormality of the pleura (HP:0002103)1.95925162
74Pulmonary infiltrates (HP:0002113)1.95219414
75Eczematoid dermatitis (HP:0000976)1.93966966
76J-shaped sella turcica (HP:0002680)1.93249508
77Aplasia/Hypoplasia of the thymus (HP:0010515)1.92466298
78Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.90801245
79Decreased activity of mitochondrial respiratory chain (HP:0008972)1.90801245
80Hepatocellular necrosis (HP:0001404)1.89850470
81Sensory axonal neuropathy (HP:0003390)1.89545832
82IgA deficiency (HP:0002720)1.89511707
83Increased hepatocellular lipid droplets (HP:0006565)1.89180353
84Myositis (HP:0100614)1.88622380
85Renal Fanconi syndrome (HP:0001994)1.86723247
86Progressive muscle weakness (HP:0003323)1.86622167
87Abnormality of male internal genitalia (HP:0000022)1.83627233
88Papilloma (HP:0012740)1.83293774
89Verrucae (HP:0200043)1.83293774
90Ureteral stenosis (HP:0000071)1.82980124
91Chest pain (HP:0100749)1.82279953
92Hepatic necrosis (HP:0002605)1.81363500
93Lipid accumulation in hepatocytes (HP:0006561)1.80912626
94Abnormality of dental color (HP:0011073)1.78959126
95Increased serum ferritin (HP:0003281)1.78388369
96Vasculitis (HP:0002633)1.76228743
97Recurrent abscess formation (HP:0002722)1.75789593
98Chronic sinusitis (HP:0011109)1.75688762
99Ureteral obstruction (HP:0006000)1.69941484
100Mesangial abnormality (HP:0001966)1.68663128

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.47134506
2KDR5.67603919
3TESK24.66210097
4VRK23.74568619
5MAP4K13.73070554
6TAOK33.19628911
7ITK2.83060647
8PIK3CA2.16253299
9SCYL22.13632320
10TEC2.05483863
11MAP3K111.97957097
12MAP4K21.95063214
13BCKDK1.89972730
14KIT1.89192379
15MATK1.81543824
16SYK1.75503560
17TESK11.69755747
18LRRK21.67393459
19BTK1.54328889
20ADRBK21.48858755
21NUAK11.41678936
22JAK31.33423991
23MAPK111.28922049
24PRKCQ1.28871209
25GRK11.22671035
26FES1.22200452
27VRK11.19980197
28ERN11.17411013
29MAP3K101.15410592
30LYN1.14447527
31NME21.14044460
32LCK1.11768790
33CSK1.09065337
34GRK61.06905864
35TBK11.04104843
36MAPK131.00975670
37BMPR20.99831467
38LIMK10.96796853
39PIM20.93782232
40CSF1R0.91608909
41RIPK40.85297151
42TNK20.83250713
43CCNB10.81684349
44IKBKB0.81319647
45PINK10.81313939
46SIK20.78967951
47IKBKE0.73320592
48CAMKK20.70692042
49MARK30.70542093
50BUB10.68534221
51NTRK10.67718666
52GRK70.67578799
53HCK0.67036541
54PLK40.65512932
55IRAK20.63000647
56ZAP700.61888820
57CDK190.60559686
58TIE10.58181421
59PIM10.58018051
60DAPK10.55271754
61TYK20.53598670
62FYN0.53329869
63MAP3K120.52855436
64BLK0.49125643
65NME10.48976090
66CAMKK10.48856272
67INSRR0.45426096
68IRAK10.45386953
69PIK3CG0.45121716
70ZAK0.42008384
71MYLK0.41011112
72IGF1R0.39908290
73BMX0.39165448
74BCR0.36445775
75MAPKAPK50.35630455
76IRAK40.35628084
77MAPK120.35579536
78ADRBK10.35108027
79CDK90.32933550
80NEK90.32929841
81MAP3K140.30005794
82RPS6KA50.29572335
83OBSCN0.28229150
84PRKCA0.27697589
85CDK80.25962030
86MAPK150.24978237
87PRKCH0.24356056
88GRK50.24082766
89TAOK20.23756268
90ERBB20.23533498
91ATR0.22421485
92INSR0.22272084
93PRKD10.20900986
94WNK40.20595566
95MAPK30.20412973
96JAK20.20225253
97FRK0.20187225
98MAPKAPK20.19566037
99CSNK1A10.19204760
100SRC0.19128531

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053407.09935868
2Graft-versus-host disease_Homo sapiens_hsa053323.66327239
3Autoimmune thyroid disease_Homo sapiens_hsa053203.62327719
4Allograft rejection_Homo sapiens_hsa053303.40930312
5Antigen processing and presentation_Homo sapiens_hsa046123.06387399
6Hematopoietic cell lineage_Homo sapiens_hsa046402.90329092
7Type I diabetes mellitus_Homo sapiens_hsa049402.66758121
8Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.59624667
9Proteasome_Homo sapiens_hsa030502.50878731
10Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.32879866
11SNARE interactions in vesicular transport_Homo sapiens_hsa041302.11816568
12Rheumatoid arthritis_Homo sapiens_hsa053231.96240800
13T cell receptor signaling pathway_Homo sapiens_hsa046601.94423568
14Asthma_Homo sapiens_hsa053101.88344449
15Intestinal immune network for IgA production_Homo sapiens_hsa046721.87977746
16Oxidative phosphorylation_Homo sapiens_hsa001901.82488184
17NF-kappa B signaling pathway_Homo sapiens_hsa040641.76499473
18Measles_Homo sapiens_hsa051621.72648058
19Parkinsons disease_Homo sapiens_hsa050121.69655715
20Phototransduction_Homo sapiens_hsa047441.57146789
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.55463403
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.48050152
23Homologous recombination_Homo sapiens_hsa034401.45845562
24Viral myocarditis_Homo sapiens_hsa054161.40960242
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.36918383
26Ribosome_Homo sapiens_hsa030101.31832416
27Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.29666634
28Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.17276432
29Staphylococcus aureus infection_Homo sapiens_hsa051501.10400225
30Peroxisome_Homo sapiens_hsa041461.09208209
31Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.07722220
32Salmonella infection_Homo sapiens_hsa051321.04602753
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.01473518
34Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01409636
35Toll-like receptor signaling pathway_Homo sapiens_hsa046200.94743400
36Herpes simplex infection_Homo sapiens_hsa051680.93604746
37RNA polymerase_Homo sapiens_hsa030200.93499335
38Alzheimers disease_Homo sapiens_hsa050100.91968058
39Leishmaniasis_Homo sapiens_hsa051400.89529665
40Drug metabolism - other enzymes_Homo sapiens_hsa009830.78951100
41Huntingtons disease_Homo sapiens_hsa050160.77203620
42Systemic lupus erythematosus_Homo sapiens_hsa053220.72456910
43Pyrimidine metabolism_Homo sapiens_hsa002400.72150713
44Glycosaminoglycan degradation_Homo sapiens_hsa005310.71296936
45Malaria_Homo sapiens_hsa051440.71056037
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.70520734
47Sulfur metabolism_Homo sapiens_hsa009200.69692709
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.69589896
49RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69181939
50Chemokine signaling pathway_Homo sapiens_hsa040620.67020157
51Purine metabolism_Homo sapiens_hsa002300.66847432
52Butanoate metabolism_Homo sapiens_hsa006500.66229376
53Shigellosis_Homo sapiens_hsa051310.64520061
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63524598
55Jak-STAT signaling pathway_Homo sapiens_hsa046300.61008764
56Phenylalanine metabolism_Homo sapiens_hsa003600.59990603
57Tyrosine metabolism_Homo sapiens_hsa003500.59002933
58B cell receptor signaling pathway_Homo sapiens_hsa046620.57106073
59Protein export_Homo sapiens_hsa030600.55920369
60N-Glycan biosynthesis_Homo sapiens_hsa005100.55462200
61Olfactory transduction_Homo sapiens_hsa047400.53956361
62DNA replication_Homo sapiens_hsa030300.50918561
63Nitrogen metabolism_Homo sapiens_hsa009100.50890986
64Influenza A_Homo sapiens_hsa051640.48930464
65Apoptosis_Homo sapiens_hsa042100.48257391
66Chemical carcinogenesis_Homo sapiens_hsa052040.47513363
67Tuberculosis_Homo sapiens_hsa051520.46202754
68HTLV-I infection_Homo sapiens_hsa051660.45349096
69Cardiac muscle contraction_Homo sapiens_hsa042600.43967335
70Osteoclast differentiation_Homo sapiens_hsa043800.42957194
71NOD-like receptor signaling pathway_Homo sapiens_hsa046210.42001952
72Nucleotide excision repair_Homo sapiens_hsa034200.41148220
73Retinol metabolism_Homo sapiens_hsa008300.40559065
74Endocytosis_Homo sapiens_hsa041440.40051845
75Collecting duct acid secretion_Homo sapiens_hsa049660.39981131
76Base excision repair_Homo sapiens_hsa034100.39748127
77Epstein-Barr virus infection_Homo sapiens_hsa051690.38277789
78Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.38235614
79Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37483586
80Fanconi anemia pathway_Homo sapiens_hsa034600.37273557
81Transcriptional misregulation in cancer_Homo sapiens_hsa052020.35599775
82Caffeine metabolism_Homo sapiens_hsa002320.33136758
83Primary bile acid biosynthesis_Homo sapiens_hsa001200.32878089
84Linoleic acid metabolism_Homo sapiens_hsa005910.32737183
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32139297
86alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31767135
87Platelet activation_Homo sapiens_hsa046110.31656384
88Non-homologous end-joining_Homo sapiens_hsa034500.30670443
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29047065
90Pertussis_Homo sapiens_hsa051330.28896117
91Arachidonic acid metabolism_Homo sapiens_hsa005900.27592862
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.27191406
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26882600
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.24943099
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.24739070
96Metabolic pathways_Homo sapiens_hsa011000.24467083
97Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.23578721
98ABC transporters_Homo sapiens_hsa020100.23297647
99Toxoplasmosis_Homo sapiens_hsa051450.20542984
100Maturity onset diabetes of the young_Homo sapiens_hsa049500.18269453

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »