TRBJ2-7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)9.74422866
2negative thymic T cell selection (GO:0045060)8.77544455
3positive regulation of gamma-delta T cell activation (GO:0046645)8.51971267
4positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)7.61396191
5positive T cell selection (GO:0043368)7.56225754
6thymic T cell selection (GO:0045061)7.31871545
7T cell selection (GO:0045058)7.29727602
8negative regulation of cell killing (GO:0031342)7.26631609
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.26631609
10positive regulation of interleukin-2 biosynthetic process (GO:0045086)7.04925012
11regulation of gamma-delta T cell differentiation (GO:0045586)7.00386861
12positive thymic T cell selection (GO:0045059)6.76408541
13regulation of isotype switching to IgG isotypes (GO:0048302)6.62978294
14interferon-gamma production (GO:0032609)6.55664500
15regulation of T cell tolerance induction (GO:0002664)6.55112451
16T cell receptor signaling pathway (GO:0050852)6.39407487
17antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.29012987
18antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.29012987
19regulation of gamma-delta T cell activation (GO:0046643)6.27408550
20response to interleukin-15 (GO:0070672)5.81368298
21T cell costimulation (GO:0031295)5.67856091
22Arp2/3 complex-mediated actin nucleation (GO:0034314)5.64848816
23cellular response to interleukin-15 (GO:0071350)5.58425102
24lymphocyte costimulation (GO:0031294)5.57803168
25pyrimidine nucleoside catabolic process (GO:0046135)5.44696748
26positive regulation of tolerance induction (GO:0002645)5.34573397
27T cell migration (GO:0072678)5.26995011
28regulation of alpha-beta T cell proliferation (GO:0046640)5.25989090
29antigen receptor-mediated signaling pathway (GO:0050851)5.25030103
30antigen processing and presentation of endogenous antigen (GO:0019883)5.21102383
31positive regulation of alpha-beta T cell proliferation (GO:0046641)5.16205123
32V(D)J recombination (GO:0033151)5.13124958
33leukocyte aggregation (GO:0070486)5.12730134
34regulation of T cell receptor signaling pathway (GO:0050856)5.12629004
35positive regulation of B cell differentiation (GO:0045579)5.08731838
36actin nucleation (GO:0045010)5.05019875
37regulation of interleukin-2 biosynthetic process (GO:0045076)4.89576297
38ribosomal small subunit assembly (GO:0000028)4.86672975
39negative regulation of T cell apoptotic process (GO:0070233)4.82066664
40activated T cell proliferation (GO:0050798)4.81574762
41regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.75238555
42negative regulation of viral genome replication (GO:0045071)4.74446818
43mast cell activation (GO:0045576)4.68819251
44regulation of tolerance induction (GO:0002643)4.68664611
45positive regulation of interleukin-2 production (GO:0032743)4.57189016
46regulation of B cell differentiation (GO:0045577)4.45727472
47regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.38883957
48positive regulation of interleukin-8 secretion (GO:2000484)4.34433252
49positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.27526604
50positive regulation of natural killer cell mediated immunity (GO:0002717)4.27526604
51regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.23424760
52regulation of natural killer cell mediated immunity (GO:0002715)4.23424760
53negative regulation of T cell mediated immunity (GO:0002710)4.19248249
54T cell differentiation (GO:0030217)4.12665758
55regulation of B cell receptor signaling pathway (GO:0050855)4.03640040
56positive regulation of isotype switching (GO:0045830)4.01991263
57negative regulation by host of viral transcription (GO:0043922)4.00501661
58alpha-beta T cell differentiation (GO:0046632)3.99638512
59positive regulation of humoral immune response (GO:0002922)3.95854665
60alpha-beta T cell activation (GO:0046631)3.93873723
61positive regulation of immunoglobulin mediated immune response (GO:0002891)3.90068958
62positive regulation of B cell mediated immunity (GO:0002714)3.90068958
63signal complex assembly (GO:0007172)3.88718177
64cytolysis (GO:0019835)3.88359837
65cellular response to interleukin-4 (GO:0071353)3.83488275
66macrophage chemotaxis (GO:0048246)3.81078760
67immune response-activating cell surface receptor signaling pathway (GO:0002429)3.77902317
68regulation of isotype switching (GO:0045191)3.73193836
69regulation of regulatory T cell differentiation (GO:0045589)3.72026630
70negative regulation of T cell receptor signaling pathway (GO:0050860)3.72025841
71T cell activation (GO:0042110)3.71038140
72regulation of defense response to virus by virus (GO:0050690)3.66419894
73regulation of immunoglobulin mediated immune response (GO:0002889)3.62491066
74sequestering of actin monomers (GO:0042989)3.61282183
75positive regulation of T cell mediated cytotoxicity (GO:0001916)3.59938408
76mast cell degranulation (GO:0043303)3.57520469
77mast cell activation involved in immune response (GO:0002279)3.57520469
78lymphocyte chemotaxis (GO:0048247)3.56934356
79eosinophil chemotaxis (GO:0048245)3.56332395
80positive regulation of immunoglobulin production (GO:0002639)3.56152717
81positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.52946240
82negative regulation of lymphocyte apoptotic process (GO:0070229)3.51536709
83regulation of leukocyte mediated cytotoxicity (GO:0001910)3.51201828
84regulation of B cell mediated immunity (GO:0002712)3.50090477
85positive regulation of DNA recombination (GO:0045911)3.47106686
86response to interleukin-4 (GO:0070670)3.45957506
87negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.43337436
88regulation of immunoglobulin production (GO:0002637)3.42731198
89positive regulation of calcium-mediated signaling (GO:0050850)3.42324726
90positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.40755452
91regulation of lymphocyte chemotaxis (GO:1901623)3.38628993
92immunoglobulin mediated immune response (GO:0016064)3.38408942
93negative regulation of lymphocyte mediated immunity (GO:0002707)3.38389086
94regulation of interleukin-2 production (GO:0032663)3.37375079
95regulation of interleukin-8 secretion (GO:2000482)3.34522491
96regulation of viral genome replication (GO:0045069)3.34402774
97positive regulation of granulocyte differentiation (GO:0030854)3.32406479
98viral transcription (GO:0019083)3.31441013
99regulation of interleukin-4 production (GO:0032673)3.27380003
100T cell homeostasis (GO:0043029)3.27220445
101positive regulation of interleukin-4 production (GO:0032753)3.26551192
102pyrimidine-containing compound catabolic process (GO:0072529)3.25928607
103eosinophil migration (GO:0072677)3.24990473
104regulation of cell killing (GO:0031341)3.23965966
105regulation of response to interferon-gamma (GO:0060330)3.23067287
106positive regulation of cell killing (GO:0031343)3.22760910
107positive regulation of immune response to tumor cell (GO:0002839)3.22696459
108regulation of immune response to tumor cell (GO:0002837)3.22696459
109regulation of response to tumor cell (GO:0002834)3.22696459
110positive regulation of response to tumor cell (GO:0002836)3.22696459
111positive regulation of T cell activation (GO:0050870)3.18814139
112leukocyte cell-cell adhesion (GO:0007159)3.18101925
113cellular defense response (GO:0006968)3.17820158
114lymphocyte migration (GO:0072676)3.17104209
115regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.16606840
116T cell proliferation (GO:0042098)3.16449715
117antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.14597230
118regulation of T cell mediated cytotoxicity (GO:0001914)3.14482606
119regulation of activation of Janus kinase activity (GO:0010533)3.14320554
120regulation of interleukin-12 biosynthetic process (GO:0045075)3.14096169
121translational termination (GO:0006415)3.13147820
122antigen processing and presentation via MHC class Ib (GO:0002475)3.12330999
123ribosomal small subunit biogenesis (GO:0042274)3.10387203
124positive regulation of T cell cytokine production (GO:0002726)3.10017743
125regulation of calcium-mediated signaling (GO:0050848)3.09637232
126positive regulation of uterine smooth muscle contraction (GO:0070474)3.08533995
127regulation of T cell apoptotic process (GO:0070232)3.05475452
128response to interferon-beta (GO:0035456)3.05174602
129positive regulation of defense response to virus by host (GO:0002230)3.05009394
130regulation of chronic inflammatory response (GO:0002676)3.04193498
131antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.03250301
132negative regulation of viral process (GO:0048525)3.02210088
133heterotypic cell-cell adhesion (GO:0034113)2.98955776
134purine deoxyribonucleotide catabolic process (GO:0009155)2.98438298
135positive regulation of lymphocyte migration (GO:2000403)2.97683960
136negative regulation of stress fiber assembly (GO:0051497)2.94848649
137positive regulation of lamellipodium assembly (GO:0010592)2.94544365
138DNA demethylation (GO:0080111)2.94006754
139chemokine-mediated signaling pathway (GO:0070098)2.91482651
140deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.91150916
141antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.87611822
142negative regulation of calcium ion transport into cytosol (GO:0010523)2.86537457
143cytidine deamination (GO:0009972)11.2615086
144cytidine metabolic process (GO:0046087)11.2615086
145cytidine catabolic process (GO:0006216)11.2615086
146regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:004509110.6727725
147DNA deamination (GO:0045006)10.2117086
148pyrimidine ribonucleoside catabolic process (GO:0046133)10.1382408

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.78197745
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.34596305
3E2F7_22180533_ChIP-Seq_HELA_Human5.12479463
4RUNX_20019798_ChIP-Seq_JUKART_Human3.97267714
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.76267737
6FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.76019127
7MYC_22102868_ChIP-Seq_BL_Human3.73552655
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.71810501
9IRF8_22096565_ChIP-ChIP_GC-B_Human3.39585333
10MYB_26560356_Chip-Seq_TH2_Human3.33449657
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.30256974
12STAT4_19710469_ChIP-ChIP_TH1__Mouse3.27603424
13STAT6_21828071_ChIP-Seq_BEAS2B_Human3.02804725
14MAF_26560356_Chip-Seq_TH1_Human2.96023013
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.87595253
16UTX_26944678_Chip-Seq_JUKART_Human2.83354498
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.69010463
18MYB_26560356_Chip-Seq_TH1_Human2.61992651
19GATA3_27048872_Chip-Seq_THYMUS_Human2.35703091
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.34095809
21RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.29077801
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.14096281
23MAF_26560356_Chip-Seq_TH2_Human2.10974999
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.07674234
25VDR_21846776_ChIP-Seq_THP-1_Human2.03867446
26KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.01774323
27IRF8_21731497_ChIP-ChIP_J774_Mouse1.99288492
28CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.83501951
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.82596932
30NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.82149573
31RUNX1_22412390_ChIP-Seq_EML_Mouse1.80906624
32SPI1_23547873_ChIP-Seq_NB4_Human1.79899521
33FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.74732642
34BP1_19119308_ChIP-ChIP_Hs578T_Human1.74371053
35E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.74329403
36NOTCH1_21737748_ChIP-Seq_TLL_Human1.73310359
37SCL_19346495_ChIP-Seq_HPC-7_Human1.70289454
38TCF7_22412390_ChIP-Seq_EML_Mouse1.69774701
39EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.69179659
40SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.64795495
41RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.61636376
42MYB_21317192_ChIP-Seq_ERMYB_Mouse1.60844750
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56512149
44KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.56232763
45TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.55739816
46VDR_24763502_ChIP-Seq_THP-1_Human1.51890678
47KDM2B_26808549_Chip-Seq_DND41_Human1.51698958
48NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.50621464
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.50009471
50IRF8_27001747_Chip-Seq_BMDM_Mouse1.49106711
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.47143148
52FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.46748924
53FOXM1_23109430_ChIP-Seq_U2OS_Human1.39734706
54CIITA_25753668_ChIP-Seq_RAJI_Human1.39130366
55MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.38555484
56VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.37915079
57VDR_23849224_ChIP-Seq_CD4+_Human1.33009768
58HTT_18923047_ChIP-ChIP_STHdh_Human1.32732569
59IGF1R_20145208_ChIP-Seq_DFB_Human1.32200588
60GATA3_26560356_Chip-Seq_TH2_Human1.31128667
61BCL6_27268052_Chip-Seq_Bcells_Human1.30983164
62FOXP3_21729870_ChIP-Seq_TREG_Human1.30127442
63SPI1_23127762_ChIP-Seq_K562_Human1.29918042
64E2F4_17652178_ChIP-ChIP_JURKAT_Human1.28494215
65SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.27490468
66VDR_22108803_ChIP-Seq_LS180_Human1.25962777
67BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23646712
68CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.21215776
69RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.18707512
70GATA2_22383799_ChIP-Seq_G1ME_Mouse1.17901025
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.16108113
72ELK1_19687146_ChIP-ChIP_HELA_Human1.15868162
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.15355439
74BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.14366550
75PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.13412064
76VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.12389059
77EST1_17652178_ChIP-ChIP_JURKAT_Human1.07678378
78EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.07181136
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.07144144
80PU_27001747_Chip-Seq_BMDM_Mouse1.06196266
81PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.05281088
82ERG_20887958_ChIP-Seq_HPC-7_Mouse1.04097402
83CTCF_20526341_ChIP-Seq_ESCs_Human1.01900664
84HOXB4_20404135_ChIP-ChIP_EML_Mouse1.00080649
85KDM2B_26808549_Chip-Seq_JURKAT_Human0.98627843
86KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98615212
87JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97529008
88P300_27268052_Chip-Seq_Bcells_Human0.97520876
89TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96351226
90NANOG_20526341_ChIP-Seq_ESCs_Human0.95917865
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95193221
92NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95090263
93SA1_27219007_Chip-Seq_Bcells_Human0.95074240
94GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.93796547
95NCOR_22424771_ChIP-Seq_293T_Human0.93388912
96RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.92783870
97PU.1_20513432_ChIP-Seq_Bcells_Mouse0.92583289
98FOXA1_21572438_ChIP-Seq_LNCaP_Human0.92377434
99TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.92262701
100GABP_17652178_ChIP-ChIP_JURKAT_Human0.91448044
101LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.90603608
102TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88931350
103CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88874800
104ELF1_20517297_ChIP-Seq_JURKAT_Human0.87927142
105BCOR_27268052_Chip-Seq_Bcells_Human0.87900701
106MYC_19079543_ChIP-ChIP_MESCs_Mouse0.87888022
107E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.87498449
108FOXA1_25329375_ChIP-Seq_VCAP_Human0.87335242
109FOXA1_27270436_Chip-Seq_PROSTATE_Human0.87335242
110PCGF2_27294783_Chip-Seq_ESCs_Mouse0.87149905
111AR_20517297_ChIP-Seq_VCAP_Human0.87022204
112CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86571531
113GATA6_21074721_ChIP-Seq_CACO-2_Human0.85731809
114RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.85325976
115CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85113050
116YY1_22570637_ChIP-Seq_MALME-3M_Human0.84687671
117XRN2_22483619_ChIP-Seq_HELA_Human0.84445165
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.83998682
119LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.83946240
120TAF2_19829295_ChIP-Seq_ESCs_Human0.83628284
121GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.82654146
122FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82473981
123PCGF2_27294783_Chip-Seq_NPCs_Mouse0.80167641
124CTCF_26484167_Chip-Seq_Bcells_Mouse0.79317372
125RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78916271
126ELK3_25401928_ChIP-Seq_HUVEC_Human0.77878587
127SRF_21415370_ChIP-Seq_HL-1_Mouse0.77392431
128GATA1_22383799_ChIP-Seq_G1ME_Mouse0.77116402
129FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.76522739
130MYC_19829295_ChIP-Seq_ESCs_Human0.75706348
131TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.75617606
132SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.74158339
133RBPJ_21746931_ChIP-Seq_IB4_Human0.73366741
134GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.73186750
135EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.73170445
136CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.73051824
137NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.71866421
138CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.71766136
139ZNF274_21170338_ChIP-Seq_K562_Hela0.71395764
140EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.70475342
141MYC_18555785_ChIP-Seq_MESCs_Mouse0.70047501
142NFE2_27457419_Chip-Seq_LIVER_Mouse0.69891728
143CTBP1_25329375_ChIP-Seq_LNCAP_Human0.69580019
144CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.69056589
145GATA1_19941827_ChIP-Seq_MEL_Mouse0.67894920
146NCOR1_26117541_ChIP-Seq_K562_Human0.67747265
147KDM5A_27292631_Chip-Seq_BREAST_Human0.66755345

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.66508607
2MP0005671_abnormal_response_to5.05847646
3MP0000685_abnormal_immune_system3.79321868
4MP0009333_abnormal_splenocyte_physiolog3.46022098
5MP0000703_abnormal_thymus_morphology3.42260163
6MP0001835_abnormal_antigen_presentation3.23079155
7MP0002166_altered_tumor_susceptibility3.20004442
8MP0001800_abnormal_humoral_immune3.19321606
9MP0002398_abnormal_bone_marrow3.17486008
10MP0002420_abnormal_adaptive_immunity3.00440725
11MP0001819_abnormal_immune_cell2.94919504
12MP0005000_abnormal_immune_tolerance2.83873331
13MP0002723_abnormal_immune_serum2.76897524
14MP0000716_abnormal_immune_system2.69043381
15MP0002722_abnormal_immune_system2.65195094
16MP0002006_tumorigenesis2.59248412
17MP0005387_immune_system_phenotype2.58724847
18MP0001790_abnormal_immune_system2.58724847
19MP0002452_abnormal_antigen_presenting2.50601778
20MP0002405_respiratory_system_inflammati2.47475956
21MP0000689_abnormal_spleen_morphology2.46006271
22MP0005025_abnormal_response_to2.35854203
23MP0009785_altered_susceptibility_to2.34747757
24MP0002396_abnormal_hematopoietic_system2.25025838
25MP0002429_abnormal_blood_cell2.18185037
26MP0003436_decreased_susceptibility_to2.17458541
27MP0004947_skin_inflammation2.17062609
28MP0003300_gastrointestinal_ulcer2.11557123
29MP0004381_abnormal_hair_follicle2.11410405
30MP0010155_abnormal_intestine_physiology2.04970885
31MP0006082_CNS_inflammation2.02277212
32MP0002148_abnormal_hypersensitivity_rea1.93058055
33MP0003724_increased_susceptibility_to1.88640902
34MP0001873_stomach_inflammation1.87009629
35MP0003866_abnormal_defecation1.86840554
36MP0002933_joint_inflammation1.85469106
37MP0003646_muscle_fatigue1.84602902
38MP0002419_abnormal_innate_immunity1.71021964
39MP0005464_abnormal_platelet_physiology1.67516969
40MP0001845_abnormal_inflammatory_respons1.63997701
41MP0000858_altered_metastatic_potential1.56529368
42MP0004808_abnormal_hematopoietic_stem1.45011998
43MP0002102_abnormal_ear_morphology1.41322561
44MP0005075_abnormal_melanosome_morpholog1.36828638
45MP0001853_heart_inflammation1.32949229
46MP0006054_spinal_hemorrhage1.32507945
47MP0000372_irregular_coat_pigmentation1.31581680
48MP0008872_abnormal_physiological_respon1.30232908
49MP0003448_altered_tumor_morphology1.25326246
50MP0000465_gastrointestinal_hemorrhage1.24413073
51MP0002009_preneoplasia1.22770009
52MP0001919_abnormal_reproductive_system1.21195021
53MP0003786_premature_aging1.20677302
54MP0004145_abnormal_muscle_electrophysio1.18203539
55MP0008995_early_reproductive_senescence1.17268623
56MP0002019_abnormal_tumor_incidence1.16846387
57MP0010352_gastrointestinal_tract_polyps1.12620294
58MP0003303_peritoneal_inflammation1.12009948
59MP0003137_abnormal_impulse_conducting1.07886490
60MP0002132_abnormal_respiratory_system1.06851481
61MP0010094_abnormal_chromosome_stability1.03977362
62MP0008057_abnormal_DNA_replication1.03278221
63MP0001545_abnormal_hematopoietic_system1.01940637
64MP0005397_hematopoietic_system_phenotyp1.01940637
65MP0005645_abnormal_hypothalamus_physiol0.99844731
66MP0002277_abnormal_respiratory_mucosa0.98774903
67MP0004957_abnormal_blastocyst_morpholog0.98670536
68MP0000490_abnormal_crypts_of0.98061710
69MP0005377_hearing/vestibular/ear_phenot0.97898701
70MP0003878_abnormal_ear_physiology0.97898701
71MP0005360_urolithiasis0.93661524
72MP0009379_abnormal_foot_pigmentation0.92154876
73MP0008469_abnormal_protein_level0.91898705
74MP0005023_abnormal_wound_healing0.89586092
75MP0003077_abnormal_cell_cycle0.89342114
76MP0001533_abnormal_skeleton_physiology0.86147268
77MP0005166_decreased_susceptibility_to0.83243913
78MP0004510_myositis0.81855124
79MP0005310_abnormal_salivary_gland0.78563613
80MP0003075_altered_response_to0.77255543
81MP0001485_abnormal_pinna_reflex0.76815814
82MP0001905_abnormal_dopamine_level0.76588983
83MP0006072_abnormal_retinal_apoptosis0.75960183
84MP0008961_abnormal_basal_metabolism0.75588913
85MP0005389_reproductive_system_phenotype0.75079828
86MP0003045_fibrosis0.72353708
87MP0001542_abnormal_bone_strength0.71965649
88MP0001851_eye_inflammation0.71059394
89MP0001348_abnormal_lacrimal_gland0.70103094
90MP0009765_abnormal_xenobiotic_induced0.68087984
91MP0002998_abnormal_bone_remodeling0.67018017
92MP0001243_abnormal_dermal_layer0.66937969
93MP0009763_increased_sensitivity_to0.65687187
94MP0008877_abnormal_DNA_methylation0.64215133
95MP0001986_abnormal_taste_sensitivity0.63296413
96MP0005636_abnormal_mineral_homeostasis0.61650296
97MP0005410_abnormal_fertilization0.61222459
98MP0005076_abnormal_cell_differentiation0.60245883
99MP0009697_abnormal_copulation0.59175655
100MP0010386_abnormal_urinary_bladder0.58818998
101MP0005379_endocrine/exocrine_gland_phen0.58717308
102MP0004185_abnormal_adipocyte_glucose0.58369442
103MP0005257_abnormal_intraocular_pressure0.57878066
104MP0003693_abnormal_embryo_hatching0.57647748
105MP0001968_abnormal_touch/_nociception0.57522524
106MP0001765_abnormal_ion_homeostasis0.57442823
107MP0002876_abnormal_thyroid_physiology0.57009976
108MP0010234_abnormal_vibrissa_follicle0.56615869
109MP0003252_abnormal_bile_duct0.56002796
110MP0009278_abnormal_bone_marrow0.55352823
111MP0000609_abnormal_liver_physiology0.55266422
112MP0000639_abnormal_adrenal_gland0.55028629
113MP0000477_abnormal_intestine_morphology0.54630481
114MP0008007_abnormal_cellular_replicative0.52932397
115MP0009643_abnormal_urine_homeostasis0.51794815
116MP0005551_abnormal_eye_electrophysiolog0.51594207
117MP0003795_abnormal_bone_structure0.50233977
118MP0002163_abnormal_gland_morphology0.50214911
119MP0005330_cardiomyopathy0.50183209
120MP0002736_abnormal_nociception_after0.49919859
121MP0000350_abnormal_cell_proliferation0.49153906
122MP0001663_abnormal_digestive_system0.49138176
123MP0008058_abnormal_DNA_repair0.49023580
124MP0009764_decreased_sensitivity_to0.48871054
125MP0001191_abnormal_skin_condition0.48745783
126MP0002693_abnormal_pancreas_physiology0.48267120
127MP0000920_abnormal_myelination0.48143891
128MP0005174_abnormal_tail_pigmentation0.48057098
129MP0008873_increased_physiological_sensi0.46898315
130MP0002822_catalepsy0.46778609
131MP0003453_abnormal_keratinocyte_physiol0.45827468
132MP0002136_abnormal_kidney_physiology0.44641778
133MP0008569_lethality_at_weaning0.44537478
134MP0000367_abnormal_coat/_hair0.44522205
135MP0002095_abnormal_skin_pigmentation0.43751961
136MP0002083_premature_death0.42147421
137MP0001216_abnormal_epidermal_layer0.41898478
138MP0000604_amyloidosis0.40755163
139MP0003111_abnormal_nucleus_morphology0.39776188
140MP0000313_abnormal_cell_death0.39269383
141MP0008770_decreased_survivor_rate0.38702358

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of T cell number (HP:0011839)9.65595540
2Aplastic anemia (HP:0001915)7.64550819
3Severe combined immunodeficiency (HP:0004430)6.53276223
4Combined immunodeficiency (HP:0005387)6.43767646
5Elevated erythrocyte sedimentation rate (HP:0003565)6.20869957
6Abnormality of T cells (HP:0002843)5.92583751
7Recurrent viral infections (HP:0004429)5.30605838
8Eosinophilia (HP:0001880)5.29164309
9IgG deficiency (HP:0004315)4.99119200
10Abnormality of eosinophils (HP:0001879)4.94431716
11Panhypogammaglobulinemia (HP:0003139)4.82603418
12Stomatitis (HP:0010280)4.79383501
13Thyroiditis (HP:0100646)4.71285204
14B lymphocytopenia (HP:0010976)4.49867237
15Abnormality of B cell number (HP:0010975)4.49867237
16Granulocytopenia (HP:0001913)4.43899593
17Recurrent fungal infections (HP:0002841)4.34616571
18Hypoplasia of the thymus (HP:0000778)4.23223041
19Leukocytosis (HP:0001974)4.14703816
20Chronic otitis media (HP:0000389)4.14096578
21Recurrent bronchitis (HP:0002837)4.10864645
22Myositis (HP:0100614)3.92130341
23Increased IgM level (HP:0003496)3.90886832
24Congenital stationary night blindness (HP:0007642)3.90660777
25Autoimmune hemolytic anemia (HP:0001890)3.86542608
26Joint swelling (HP:0001386)3.76939928
27Nasal polyposis (HP:0100582)3.71029822
28Abnormality of macrophages (HP:0004311)3.69452765
29Pustule (HP:0200039)3.61799998
30IgM deficiency (HP:0002850)3.27560718
31Lymphopenia (HP:0001888)3.27068406
32Chronic mucocutaneous candidiasis (HP:0002728)3.19021531
33Recurrent cutaneous fungal infections (HP:0011370)3.19021531
34Thrombocytosis (HP:0001894)3.18176437
35Abnormality of cells of the lymphoid lineage (HP:0012140)3.17335836
36Chronic diarrhea (HP:0002028)3.08322262
37Abnormality of the nasal mucosa (HP:0000433)3.07392683
38Abnormal delayed hypersensitivity skin test (HP:0002963)3.07391755
39Autoimmune thrombocytopenia (HP:0001973)3.02217174
40Encephalitis (HP:0002383)2.98928766
41Eczematoid dermatitis (HP:0000976)2.95999633
42Abnormality of the fingertips (HP:0001211)2.95934135
43Abnormality of the prostate (HP:0008775)2.90813398
44Meningitis (HP:0001287)2.88553453
45Lymphoma (HP:0002665)2.80553321
46Spontaneous hematomas (HP:0007420)2.73843417
473-Methylglutaconic aciduria (HP:0003535)2.69045153
48Basal cell carcinoma (HP:0002671)2.68053898
49Abnormality of T cell physiology (HP:0011840)2.66518824
50Hypergammaglobulinemia (HP:0010702)2.62894525
51Papilloma (HP:0012740)2.62590521
52Verrucae (HP:0200043)2.62590521
53Gangrene (HP:0100758)2.57348368
54Gastrointestinal infarctions (HP:0005244)2.49119197
55Increased intramyocellular lipid droplets (HP:0012240)2.48852040
56Oral leukoplakia (HP:0002745)2.48162182
57Absent rod-and cone-mediated responses on ERG (HP:0007688)2.48099081
58Recurrent otitis media (HP:0000403)2.47011871
59Recurrent abscess formation (HP:0002722)2.43325803
60Mitochondrial inheritance (HP:0001427)2.43104787
61Pancytopenia (HP:0001876)2.41958662
62Keratoconjunctivitis sicca (HP:0001097)2.34896339
63Bronchitis (HP:0012387)2.33097040
64Abnormal platelet volume (HP:0011876)2.32362778
65Pigmentary retinal degeneration (HP:0001146)2.29734930
66Severe visual impairment (HP:0001141)2.29369139
67Cellular immunodeficiency (HP:0005374)2.28392181
68Recurrent sinusitis (HP:0011108)2.28162291
69Hypoalbuminemia (HP:0003073)2.28161436
70Abnormal albumin level (HP:0012116)2.28161436
71Stomach cancer (HP:0012126)2.27204143
72Retrobulbar optic neuritis (HP:0100654)2.22155246
73Optic neuritis (HP:0100653)2.22155246
74Agammaglobulinemia (HP:0004432)2.20644436
75Aplasia/Hypoplasia of the thymus (HP:0010515)2.20509071
76Abnormal rod and cone electroretinograms (HP:0008323)2.19545097
77Chronic sinusitis (HP:0011109)2.18283240
78Amyotrophic lateral sclerosis (HP:0007354)2.18036197
79Hemoptysis (HP:0002105)2.17494300
80Hemiplegia (HP:0002301)2.17447554
81Hypoproteinemia (HP:0003075)2.17157231
82Increased muscle lipid content (HP:0009058)2.16555795
83Recurrent skin infections (HP:0001581)2.15710669
84Hepatocellular necrosis (HP:0001404)2.13796259
85Mediastinal lymphadenopathy (HP:0100721)2.12943075
86Abnormality of oral frenula (HP:0000190)2.12534479
87Keratoconjunctivitis (HP:0001096)2.09956872
88Radial bowing (HP:0002986)2.07370930
89Colon cancer (HP:0003003)2.07150247
9011 pairs of ribs (HP:0000878)2.05551753
91Orchitis (HP:0100796)2.05395792
92Decreased electroretinogram (ERG) amplitude (HP:0000654)2.03176716
93Vasculitis (HP:0002633)2.02141109
94Increased mean platelet volume (HP:0011877)2.00161721
95T lymphocytopenia (HP:0005403)10.0534799
96Increased IgE level (HP:0003212)1.99271576
97Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.95828136
98Decreased activity of mitochondrial respiratory chain (HP:0008972)1.95828136
99Obstructive lung disease (HP:0006536)1.95731845
100Chronic obstructive pulmonary disease (HP:0006510)1.95731845
101Epistaxis (HP:0000421)1.92250960
102Amaurosis fugax (HP:0100576)1.91789095
103Inflammation of the large intestine (HP:0002037)1.91711692
104Abnormality of cells of the erythroid lineage (HP:0012130)1.91581771
105Pulmonary infiltrates (HP:0002113)1.89672871
106Gastrointestinal inflammation (HP:0004386)1.87808246
107Abnormality of the alveolar ridges (HP:0006477)1.87607667
108Renal cortical cysts (HP:0000803)1.86722353
109Pulmonary embolism (HP:0002204)1.84861258
110Abnormal mitochondria in muscle tissue (HP:0008316)1.82503861
111Recurrent bacterial skin infections (HP:0005406)1.82492623
112Abnormality of the pleura (HP:0002103)1.81646839
113Trigonocephaly (HP:0000243)1.81416544
114Acute necrotizing encephalopathy (HP:0006965)1.81391736
115IgA deficiency (HP:0002720)1.79441571
116Reticulocytopenia (HP:0001896)1.78453253
117Bicuspid aortic valve (HP:0001647)1.78392860
118Abnormality of the thymus (HP:0000777)1.77546785
119Arterial thrombosis (HP:0004420)1.77506932
120Ureteral stenosis (HP:0000071)1.74537451
121Chest pain (HP:0100749)1.71715067
122Hepatitis (HP:0012115)1.71097540
123Bronchiectasis (HP:0002110)1.70881277
124Hepatic necrosis (HP:0002605)1.69932152
125Abnormal number of erythroid precursors (HP:0012131)1.69857097
126Abnormal foot bone ossification (HP:0010675)1.69739910
127Decreased central vision (HP:0007663)1.69015959
128Broad palm (HP:0001169)1.68688569
129Alkalosis (HP:0001948)1.68672403
130Periodontitis (HP:0000704)1.68294035
131Petechiae (HP:0000967)1.68050075
132Volvulus (HP:0002580)1.67607197
133Ureteral obstruction (HP:0006000)1.67501963
134Acute hepatic failure (HP:0006554)1.66928377
135Pulmonary fibrosis (HP:0002206)1.66158413
136Prolonged bleeding time (HP:0003010)1.65921496
137Increased CSF lactate (HP:0002490)1.63670566
138Abnormality of the pericardium (HP:0001697)1.61946811
139Pancreatitis (HP:0001733)1.60188191
140Type I transferrin isoform profile (HP:0003642)1.60180836

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK7.13120040
2MAP4K15.90246229
3ITK3.86250584
4BCKDK3.58324526
5ZAP703.31610373
6STK102.98074649
7TAOK32.96646551
8NLK2.68117979
9JAK32.55163707
10GRK62.50713289
11MST42.50546367
12FGFR42.41988986
13TYK22.22213446
14SCYL22.10812727
15TESK12.08971495
16IKBKE2.06075428
17LCK2.03618347
18TEC2.00274675
19CSK1.74940237
20MAP3K111.71939114
21MAP3K141.71528489
22SYK1.68208824
23FGFR31.68124051
24EEF2K1.60864744
25JAK11.54123688
26LRRK21.53103512
27NME21.52620795
28CLK11.50792937
29BTK1.46595326
30MAP3K131.44659067
31PINK11.43995370
32CAMKK11.42954847
33PKN21.36940686
34HCK1.35029583
35PRKCH1.33286612
36MAP3K101.26573776
37PRKCQ1.26320599
38STK161.25959955
39LIMK11.24249917
40MAPKAPK31.21941275
41PIK3CA1.14656352
42MAP3K71.07239007
43CAMKK21.06396381
44TBK11.06289641
45ADRBK21.05261592
46GRK11.00920209
47MARK30.97894720
48TAOK10.95187569
49PRPF4B0.94047906
50PIM10.93623531
51BUB10.90009987
52MELK0.88970279
53BLK0.87551874
54TESK20.82395557
55VRK20.79548655
56RIPK40.78960674
57LYN0.76479314
58TIE10.76119387
59PASK0.75654528
60SIK20.75434881
61FES0.74941068
62KDR0.73184206
63PDGFRB0.71904475
64MAPK70.69849350
65STK40.69416415
66JAK20.69108473
67IKBKB0.69097677
68CDK40.67713575
69MAP3K30.66653046
70RPS6KB20.64694907
71RPS6KA40.63629108
72TSSK60.62341706
73FGFR20.61198457
74FYN0.60454891
75FGFR10.60331153
76CDC70.59884077
77NUAK10.57825628
78KIT0.56161462
79MARK20.55855609
80INSR0.55855543
81INSRR0.55807203
82CSF1R0.55746024
83TYRO30.54244851
84MAPK150.51676724
85GRK70.51310054
86NEK60.50291423
87IRAK40.50176998
88VRK10.49937302
89SIK30.49294250
90MAPK120.48186347
91TGFBR10.47655464
92ROCK10.47312398
93OBSCN0.47211499
94FLT30.46368240
95IGF1R0.46160506
96DAPK10.46019703
97MAP3K120.45531153
98RPS6KA50.45268427
99MAP2K60.44714272
100ALK0.44013594
101FRK0.43967375
102PDK10.43801750
103TGFBR20.43654442
104HIPK20.43068032
105EPHB10.43020871
106TAOK20.42267895
107CDK120.41964929
108PIK3CG0.41617805
109TNK20.41172354
110CDK90.40843471
111CDK60.38306554
112MYLK0.36730275
113MAP3K50.36690981
114PRKCA0.36077087
115TRIB30.35706764
116MAPK40.35468446
117MAP4K20.35348402
118RPS6KA60.34174550
119TRPM70.34157807
120WNK40.33025027
121ACVR1B0.32653911
122CHUK0.31867243
123MATK0.30825383
124EPHA30.29591690
125MAPK110.29431230
126MAPK30.29137220
127MUSK0.28429358
128ILK0.28220703
129OXSR10.27847734
130PTK60.27464233
131CDK190.27238999
132RPS6KC10.27165515
133RPS6KL10.27165515
134CDK80.26495310
135MAP3K80.25026122
136EIF2AK30.24422988
137BRD40.23562004
138PRKACA0.23142619
139MAPK130.22787350
140CAMK2A0.22368453
141PAK10.21373378
142TLK10.21363750
143PRKCB0.21167666
144EGFR0.21077485
145RAF10.20388590
146MAPK90.20374529
147SRPK10.19758552
148TTN0.19701160
149PRKD20.19228298
150ARAF0.18107338
151ERBB30.18036276
152ROCK20.16930528
153AURKA0.16386014
154PRKCD0.16243309
155MAPKAPK20.16147089
156SRC0.15555627

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.47409523
2T cell receptor signaling pathway_Homo sapiens_hsa046604.69008726
3Graft-versus-host disease_Homo sapiens_hsa053323.56998538
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.45930355
5Measles_Homo sapiens_hsa051622.92434537
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.84587621
7Antigen processing and presentation_Homo sapiens_hsa046122.79599076
8Hematopoietic cell lineage_Homo sapiens_hsa046402.67243828
9Allograft rejection_Homo sapiens_hsa053302.49052866
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.23757489
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.23189538
12Ribosome_Homo sapiens_hsa030102.15545580
13Non-homologous end-joining_Homo sapiens_hsa034502.09190286
14Oxidative phosphorylation_Homo sapiens_hsa001901.98311590
15Viral myocarditis_Homo sapiens_hsa054161.89807892
16Autoimmune thyroid disease_Homo sapiens_hsa053201.72922466
17Parkinsons disease_Homo sapiens_hsa050121.62194580
18Type I diabetes mellitus_Homo sapiens_hsa049401.62029964
19Leukocyte transendothelial migration_Homo sapiens_hsa046701.55275990
20Leishmaniasis_Homo sapiens_hsa051401.52865954
21Osteoclast differentiation_Homo sapiens_hsa043801.50198222
22Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.49703127
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.47412613
24RNA polymerase_Homo sapiens_hsa030201.44996253
25Herpes simplex infection_Homo sapiens_hsa051681.39918571
26Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.34141504
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.33368194
28Colorectal cancer_Homo sapiens_hsa052101.33298335
29Acute myeloid leukemia_Homo sapiens_hsa052211.31192332
30Chemokine signaling pathway_Homo sapiens_hsa040621.29769722
31RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.29689781
32B cell receptor signaling pathway_Homo sapiens_hsa046621.27587920
33HTLV-I infection_Homo sapiens_hsa051661.20010963
34Hepatitis B_Homo sapiens_hsa051611.19048679
35Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.17966413
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16769606
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.15611816
38Alzheimers disease_Homo sapiens_hsa050101.13416041
39Nitrogen metabolism_Homo sapiens_hsa009101.10206319
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.08876286
41Spliceosome_Homo sapiens_hsa030401.08573807
42NOD-like receptor signaling pathway_Homo sapiens_hsa046211.04274386
43Toxoplasmosis_Homo sapiens_hsa051451.00404561
44Shigellosis_Homo sapiens_hsa051310.97744167
45Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.96189966
46Cardiac muscle contraction_Homo sapiens_hsa042600.95594207
47Phototransduction_Homo sapiens_hsa047440.95538539
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.93408990
49DNA replication_Homo sapiens_hsa030300.91047347
50Pancreatic cancer_Homo sapiens_hsa052120.90791196
51Influenza A_Homo sapiens_hsa051640.89371484
52Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88448183
53Caffeine metabolism_Homo sapiens_hsa002320.86847503
54Mismatch repair_Homo sapiens_hsa034300.85792517
55Thyroid cancer_Homo sapiens_hsa052160.83158922
56Viral carcinogenesis_Homo sapiens_hsa052030.82787375
57Protein export_Homo sapiens_hsa030600.80800802
58Apoptosis_Homo sapiens_hsa042100.80651697
59Platelet activation_Homo sapiens_hsa046110.78623553
60Linoleic acid metabolism_Homo sapiens_hsa005910.78464290
61Epstein-Barr virus infection_Homo sapiens_hsa051690.78308749
62Chronic myeloid leukemia_Homo sapiens_hsa052200.78189252
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78085281
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77702634
65alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.74310210
66Huntingtons disease_Homo sapiens_hsa050160.73105199
67Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70405062
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.68486347
69TNF signaling pathway_Homo sapiens_hsa046680.67800692
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.64816253
71Hepatitis C_Homo sapiens_hsa051600.64159775
72Toll-like receptor signaling pathway_Homo sapiens_hsa046200.61102317
73Legionellosis_Homo sapiens_hsa051340.59603279
74AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59520988
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59119057
76Staphylococcus aureus infection_Homo sapiens_hsa051500.57891071
77Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.57226396
78Non-small cell lung cancer_Homo sapiens_hsa052230.56682814
79Chemical carcinogenesis_Homo sapiens_hsa052040.55866535
80Peroxisome_Homo sapiens_hsa041460.55384732
81Retinol metabolism_Homo sapiens_hsa008300.55244896
82Endometrial cancer_Homo sapiens_hsa052130.55009028
83Pyrimidine metabolism_Homo sapiens_hsa002400.53162238
84Base excision repair_Homo sapiens_hsa034100.52084156
85Proteasome_Homo sapiens_hsa030500.51181797
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.50972700
87Prostate cancer_Homo sapiens_hsa052150.50132356
88VEGF signaling pathway_Homo sapiens_hsa043700.48601579
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47337301
90Salmonella infection_Homo sapiens_hsa051320.46022629
91Tuberculosis_Homo sapiens_hsa051520.45658148
92RNA degradation_Homo sapiens_hsa030180.45341271
93Adherens junction_Homo sapiens_hsa045200.44841291
94Notch signaling pathway_Homo sapiens_hsa043300.44837733
95p53 signaling pathway_Homo sapiens_hsa041150.43845082
96Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.43634366
97Asthma_Homo sapiens_hsa053100.43321378
98Nucleotide excision repair_Homo sapiens_hsa034200.42884764
99Olfactory transduction_Homo sapiens_hsa047400.42805224
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42733521
101FoxO signaling pathway_Homo sapiens_hsa040680.42055160
102Rheumatoid arthritis_Homo sapiens_hsa053230.41918833
103Small cell lung cancer_Homo sapiens_hsa052220.40933791
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.40916274
105mRNA surveillance pathway_Homo sapiens_hsa030150.40861283
106Prolactin signaling pathway_Homo sapiens_hsa049170.40817240
107Propanoate metabolism_Homo sapiens_hsa006400.40202715
108Systemic lupus erythematosus_Homo sapiens_hsa053220.40113846
109Endocytosis_Homo sapiens_hsa041440.39683520
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.38217563
111Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37724312
112Malaria_Homo sapiens_hsa051440.35910573
113Pertussis_Homo sapiens_hsa051330.34975436
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.34727700
115Rap1 signaling pathway_Homo sapiens_hsa040150.34173205
116African trypanosomiasis_Homo sapiens_hsa051430.33933647
117Homologous recombination_Homo sapiens_hsa034400.33178512
118Cell cycle_Homo sapiens_hsa041100.33074247
119RNA transport_Homo sapiens_hsa030130.32090798
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30200418
121mTOR signaling pathway_Homo sapiens_hsa041500.23944233
122Dorso-ventral axis formation_Homo sapiens_hsa043200.22052983
123Purine metabolism_Homo sapiens_hsa002300.22015275
124Regulation of autophagy_Homo sapiens_hsa041400.21719494
125Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.21578432
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.20818143
127MicroRNAs in cancer_Homo sapiens_hsa052060.20752039
128Renal cell carcinoma_Homo sapiens_hsa052110.20171218
129Pentose phosphate pathway_Homo sapiens_hsa000300.18958767
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18788769
131Insulin resistance_Homo sapiens_hsa049310.18483308
132MAPK signaling pathway_Homo sapiens_hsa040100.18441280
133Pathways in cancer_Homo sapiens_hsa052000.17998578
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.17598247
135One carbon pool by folate_Homo sapiens_hsa006700.17452190
136Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.17219364
137Alcoholism_Homo sapiens_hsa050340.12455988
138Ras signaling pathway_Homo sapiens_hsa040140.11603295
139Fanconi anemia pathway_Homo sapiens_hsa034600.10773146
140Fatty acid elongation_Homo sapiens_hsa000620.10358588
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.10321237
142Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.09386544
143Ovarian steroidogenesis_Homo sapiens_hsa049130.09353947

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