

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of hormone biosynthetic process (GO:0046886) | 9.42587313 |
| 2 | positive regulation of fibroblast migration (GO:0010763) | 8.56202353 |
| 3 | positive regulation of protein sumoylation (GO:0033235) | 7.65450551 |
| 4 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 7.01693230 |
| 5 | positive regulation of hormone metabolic process (GO:0032352) | 6.89142759 |
| 6 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 6.88765062 |
| 7 | positive regulation of glycolytic process (GO:0045821) | 6.85392458 |
| 8 | negative regulation of heart rate (GO:0010459) | 6.74732171 |
| 9 | mRNA cleavage (GO:0006379) | 6.25703499 |
| 10 | mRNA transcription (GO:0009299) | 6.04990554 |
| 11 | regulation of glomerular filtration (GO:0003093) | 6.02985772 |
| 12 | nerve growth factor signaling pathway (GO:0038180) | 5.84321341 |
| 13 | negative regulation of T cell mediated immunity (GO:0002710) | 5.75031605 |
| 14 | positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) | 5.61627879 |
| 15 | negative regulation of interleukin-2 production (GO:0032703) | 5.44311412 |
| 16 | NIK/NF-kappaB signaling (GO:0038061) | 5.05626304 |
| 17 | positive regulation of T cell cytokine production (GO:0002726) | 5.04150253 |
| 18 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.99014020 |
| 19 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.98740952 |
| 20 | cellular response to nerve growth factor stimulus (GO:1990090) | 4.92575869 |
| 21 | response to nerve growth factor (GO:1990089) | 4.92575869 |
| 22 | positive regulation of erythrocyte differentiation (GO:0045648) | 4.80763824 |
| 23 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.79234780 |
| 24 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 4.77761965 |
| 25 | T-helper cell differentiation (GO:0042093) | 4.77761965 |
| 26 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.64096551 |
| 27 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.64096551 |
| 28 | regulation of protein sumoylation (GO:0033233) | 4.56023611 |
| 29 | cellular response to nicotine (GO:0071316) | 4.54014363 |
| 30 | positive regulation of circadian rhythm (GO:0042753) | 4.49931424 |
| 31 | cellular response to interleukin-4 (GO:0071353) | 4.38396097 |
| 32 | positive regulation of T cell chemotaxis (GO:0010820) | 4.38361348 |
| 33 | regulation of T cell chemotaxis (GO:0010819) | 4.38361348 |
| 34 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 4.35493239 |
| 35 | positive regulation of granulocyte differentiation (GO:0030854) | 4.35477460 |
| 36 | regulation of circadian sleep/wake cycle, sleep (GO:0045187) | 4.23981292 |
| 37 | regulation of circadian sleep/wake cycle (GO:0042749) | 4.23981292 |
| 38 | positive regulation of cell killing (GO:0031343) | 4.23938153 |
| 39 | T cell differentiation involved in immune response (GO:0002292) | 4.23293075 |
| 40 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 4.23293075 |
| 41 | alpha-beta T cell activation involved in immune response (GO:0002287) | 4.23293075 |
| 42 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.21720720 |
| 43 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.20590087 |
| 44 | fucose catabolic process (GO:0019317) | 4.19629800 |
| 45 | L-fucose metabolic process (GO:0042354) | 4.19629800 |
| 46 | L-fucose catabolic process (GO:0042355) | 4.19629800 |
| 47 | activated T cell proliferation (GO:0050798) | 4.14398799 |
| 48 | renal system process involved in regulation of blood volume (GO:0001977) | 4.12894840 |
| 49 | positive regulation of T-helper 1 type immune response (GO:0002827) | 4.12773381 |
| 50 | negative regulation of alpha-beta T cell activation (GO:0046636) | 4.09003628 |
| 51 | protein polyglutamylation (GO:0018095) | 3.93636095 |
| 52 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.89587087 |
| 53 | positive regulation vascular endothelial growth factor production (GO:0010575) | 3.89157878 |
| 54 | lymphocyte chemotaxis (GO:0048247) | 3.88503539 |
| 55 | radial glial cell differentiation (GO:0060019) | 3.86202348 |
| 56 | regulation of T cell cytokine production (GO:0002724) | 3.85862856 |
| 57 | response to interleukin-4 (GO:0070670) | 3.83325032 |
| 58 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.81390725 |
| 59 | regulation of cell killing (GO:0031341) | 3.76111657 |
| 60 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.73281410 |
| 61 | regulation of memory T cell differentiation (GO:0043380) | 3.71942034 |
| 62 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.66661748 |
| 63 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.66184824 |
| 64 | regulation of glycolytic process (GO:0006110) | 3.65647186 |
| 65 | positive regulation of type 2 immune response (GO:0002830) | 3.60400577 |
| 66 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.58434825 |
| 67 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.53563933 |
| 68 | regulation of hormone biosynthetic process (GO:0046885) | 3.50447372 |
| 69 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.48269704 |
| 70 | regulation of urine volume (GO:0035809) | 3.47974479 |
| 71 | interkinetic nuclear migration (GO:0022027) | 3.45995601 |
| 72 | positive regulation of response to biotic stimulus (GO:0002833) | 3.45723553 |
| 73 | embryonic placenta development (GO:0001892) | 3.44484603 |
| 74 | response to interleukin-15 (GO:0070672) | 3.44367092 |
| 75 | cellular response to interleukin-15 (GO:0071350) | 3.42551791 |
| 76 | regulation of fibroblast migration (GO:0010762) | 3.39856158 |
| 77 | regulation of superoxide anion generation (GO:0032928) | 3.38297607 |
| 78 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 3.37558960 |
| 79 | positive regulation of heart rate (GO:0010460) | 3.35620167 |
| 80 | regulation of vascular endothelial growth factor production (GO:0010574) | 3.33514184 |
| 81 | positive regulation by host of viral transcription (GO:0043923) | 3.28667159 |
| 82 | circadian sleep/wake cycle process (GO:0022410) | 3.27012406 |
| 83 | regulation of T-helper 1 type immune response (GO:0002825) | 3.26261850 |
| 84 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 3.23630381 |
| 85 | negative regulation of necroptotic process (GO:0060546) | 3.22563314 |
| 86 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.22411612 |
| 87 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.22355184 |
| 88 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 3.21004054 |
| 89 | regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418) | 3.20261386 |
| 90 | developmental pigmentation (GO:0048066) | 3.20120843 |
| 91 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 3.15976072 |
| 92 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 3.15976072 |
| 93 | regulation of renal sodium excretion (GO:0035813) | 3.13791871 |
| 94 | negative regulation of adaptive immune response (GO:0002820) | 3.13699380 |
| 95 | tongue development (GO:0043586) | 3.12946145 |
| 96 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.12724638 |
| 97 | negative regulation of heart contraction (GO:0045822) | 3.12022144 |
| 98 | regulation of RIG-I signaling pathway (GO:0039535) | 11.7222365 |
| 99 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 11.0593164 |
| 100 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 10.3543439 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.85412911 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.67318574 |
| 3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 5.26666397 |
| 4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.05987961 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 4.02906714 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.84971337 |
| 7 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.45536780 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.45223047 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.22913524 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.04121810 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.95017152 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.88857604 |
| 13 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.82767502 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.82664256 |
| 15 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.62748112 |
| 16 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.57519791 |
| 17 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.44903530 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 2.43972411 |
| 19 | GATA1_22025678_ChIP-Seq_K562_Human | 2.38545031 |
| 20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.37894904 |
| 21 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.35451171 |
| 22 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.32399782 |
| 23 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.29793094 |
| 24 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.29287348 |
| 25 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.19015535 |
| 26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.14791447 |
| 27 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.09811211 |
| 28 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.99050989 |
| 29 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.86424891 |
| 30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.80916884 |
| 31 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.78271891 |
| 32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74388754 |
| 33 | MYB_26560356_Chip-Seq_TH1_Human | 1.71030393 |
| 34 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.68372614 |
| 35 | UTX_26944678_Chip-Seq_JUKART_Human | 1.62367566 |
| 36 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.60720967 |
| 37 | GATA3_26560356_Chip-Seq_TH2_Human | 1.59071351 |
| 38 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.57064423 |
| 39 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.52649142 |
| 40 | MAF_26560356_Chip-Seq_TH1_Human | 1.47791944 |
| 41 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.47089376 |
| 42 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.44485693 |
| 43 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.44405976 |
| 44 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.44002756 |
| 45 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.35133953 |
| 46 | SPI1_23127762_ChIP-Seq_K562_Human | 1.33962354 |
| 47 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.28509085 |
| 48 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28468240 |
| 49 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.28326866 |
| 50 | MAF_26560356_Chip-Seq_TH2_Human | 1.21898346 |
| 51 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.19785621 |
| 52 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.18744964 |
| 53 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.13703591 |
| 54 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.12473330 |
| 55 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08983882 |
| 56 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.06831194 |
| 57 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.05944902 |
| 58 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.00622196 |
| 59 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99523365 |
| 60 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.98878161 |
| 61 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.97464149 |
| 62 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96182978 |
| 63 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.95395265 |
| 64 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.94704304 |
| 65 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.90979956 |
| 66 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.90757952 |
| 67 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.88289572 |
| 68 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.87067425 |
| 69 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.86537312 |
| 70 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85987365 |
| 71 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83368952 |
| 72 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.82107412 |
| 73 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.81741043 |
| 74 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78741339 |
| 75 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.78620500 |
| 76 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.78253532 |
| 77 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.77787731 |
| 78 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77700018 |
| 79 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.77612050 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.75653574 |
| 81 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.73042911 |
| 82 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.71742395 |
| 83 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.71508908 |
| 84 | MYC_22102868_ChIP-Seq_BL_Human | 0.70309576 |
| 85 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.69183371 |
| 86 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.67819079 |
| 87 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.67789507 |
| 88 | GATA2_19941826_ChIP-Seq_K562_Human | 0.65794888 |
| 89 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.65110777 |
| 90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.64777692 |
| 91 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.64509110 |
| 92 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.64505608 |
| 93 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.64259128 |
| 94 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.64250183 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.64042598 |
| 96 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.63933744 |
| 97 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.63675635 |
| 98 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.62465941 |
| 99 | ERA_21632823_ChIP-Seq_H3396_Human | 0.62429397 |
| 100 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.62375064 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 5.00890609 |
| 2 | MP0004381_abnormal_hair_follicle | 4.53454919 |
| 3 | MP0003724_increased_susceptibility_to | 4.11512974 |
| 4 | MP0005387_immune_system_phenotype | 4.07869727 |
| 5 | MP0001790_abnormal_immune_system | 4.07869727 |
| 6 | MP0008260_abnormal_autophagy | 3.91043725 |
| 7 | MP0000372_irregular_coat_pigmentation | 3.68839868 |
| 8 | MP0005075_abnormal_melanosome_morpholog | 3.53791089 |
| 9 | MP0005671_abnormal_response_to | 2.98362691 |
| 10 | MP0002796_impaired_skin_barrier | 2.85879673 |
| 11 | MP0004510_myositis | 2.80486516 |
| 12 | MP0001800_abnormal_humoral_immune | 2.63991184 |
| 13 | MP0001853_heart_inflammation | 2.53464580 |
| 14 | MP0001873_stomach_inflammation | 2.43834589 |
| 15 | MP0002254_reproductive_system_inflammat | 2.42314880 |
| 16 | MP0002138_abnormal_hepatobiliary_system | 2.40805049 |
| 17 | MP0006082_CNS_inflammation | 2.36442506 |
| 18 | MP0009333_abnormal_splenocyte_physiolog | 2.30324672 |
| 19 | MP0003763_abnormal_thymus_physiology | 2.30293644 |
| 20 | MP0000685_abnormal_immune_system | 2.22837210 |
| 21 | MP0003172_abnormal_lysosome_physiology | 2.18264823 |
| 22 | MP0003453_abnormal_keratinocyte_physiol | 2.16197217 |
| 23 | MP0005000_abnormal_immune_tolerance | 2.04054009 |
| 24 | MP0002723_abnormal_immune_serum | 2.00049282 |
| 25 | MP0002420_abnormal_adaptive_immunity | 1.96326217 |
| 26 | MP0001819_abnormal_immune_cell | 1.89363987 |
| 27 | MP0001958_emphysema | 1.88918804 |
| 28 | MP0005310_abnormal_salivary_gland | 1.87854279 |
| 29 | MP0001835_abnormal_antigen_presentation | 1.87103584 |
| 30 | MP0003828_pulmonary_edema | 1.84393362 |
| 31 | MP0002452_abnormal_antigen_presenting | 1.82622381 |
| 32 | MP0002132_abnormal_respiratory_system | 1.74165945 |
| 33 | MP0001881_abnormal_mammary_gland | 1.70714777 |
| 34 | MP0002405_respiratory_system_inflammati | 1.68367363 |
| 35 | MP0003436_decreased_susceptibility_to | 1.56750054 |
| 36 | MP0005025_abnormal_response_to | 1.51726380 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.46916797 |
| 38 | MP0002419_abnormal_innate_immunity | 1.44811807 |
| 39 | MP0001851_eye_inflammation | 1.44698903 |
| 40 | MP0001502_abnormal_circadian_rhythm | 1.42997218 |
| 41 | MP0000716_abnormal_immune_system | 1.41595354 |
| 42 | MP0002277_abnormal_respiratory_mucosa | 1.38784034 |
| 43 | MP0002638_abnormal_pupillary_reflex | 1.35557350 |
| 44 | MP0002398_abnormal_bone_marrow | 1.35523359 |
| 45 | MP0000703_abnormal_thymus_morphology | 1.33770110 |
| 46 | MP0004947_skin_inflammation | 1.32082085 |
| 47 | MP0000689_abnormal_spleen_morphology | 1.30964154 |
| 48 | MP0000627_abnormal_mammary_gland | 1.30433154 |
| 49 | MP0003866_abnormal_defecation | 1.27920266 |
| 50 | MP0002148_abnormal_hypersensitivity_rea | 1.23092235 |
| 51 | MP0002722_abnormal_immune_system | 1.21651129 |
| 52 | MP0010155_abnormal_intestine_physiology | 1.18654036 |
| 53 | MP0009785_altered_susceptibility_to | 1.18588802 |
| 54 | MP0001845_abnormal_inflammatory_respons | 1.18037018 |
| 55 | MP0002429_abnormal_blood_cell | 1.17499177 |
| 56 | MP0003011_delayed_dark_adaptation | 1.16969133 |
| 57 | MP0005501_abnormal_skin_physiology | 1.14239521 |
| 58 | MP0001663_abnormal_digestive_system | 1.12276583 |
| 59 | MP0002933_joint_inflammation | 1.09050143 |
| 60 | MP0004270_analgesia | 1.06009545 |
| 61 | MP0004484_altered_response_of | 0.97478392 |
| 62 | MP0008469_abnormal_protein_level | 0.94759122 |
| 63 | MP0003448_altered_tumor_morphology | 0.93250052 |
| 64 | MP0002166_altered_tumor_susceptibility | 0.90516171 |
| 65 | MP0008874_decreased_physiological_sensi | 0.90343912 |
| 66 | MP0003136_yellow_coat_color | 0.89697371 |
| 67 | MP0001533_abnormal_skeleton_physiology | 0.85780711 |
| 68 | MP0009763_increased_sensitivity_to | 0.85595707 |
| 69 | MP0000609_abnormal_liver_physiology | 0.84855064 |
| 70 | MP0002970_abnormal_white_adipose | 0.84671865 |
| 71 | MP0002653_abnormal_ependyma_morphology | 0.79876500 |
| 72 | MP0000465_gastrointestinal_hemorrhage | 0.75688647 |
| 73 | MP0003936_abnormal_reproductive_system | 0.75645936 |
| 74 | MP0004742_abnormal_vestibular_system | 0.69578213 |
| 75 | MP0000015_abnormal_ear_pigmentation | 0.68003037 |
| 76 | MP0002971_abnormal_brown_adipose | 0.66577508 |
| 77 | MP0001984_abnormal_olfaction | 0.65791204 |
| 78 | MP0006036_abnormal_mitochondrial_physio | 0.63318449 |
| 79 | MP0002006_tumorigenesis | 0.63279613 |
| 80 | MP0002133_abnormal_respiratory_system | 0.62972330 |
| 81 | MP0005388_respiratory_system_phenotype | 0.62972330 |
| 82 | MP0001243_abnormal_dermal_layer | 0.62831968 |
| 83 | MP0000749_muscle_degeneration | 0.61848267 |
| 84 | MP0005377_hearing/vestibular/ear_phenot | 0.60409658 |
| 85 | MP0003878_abnormal_ear_physiology | 0.60409658 |
| 86 | MP0002098_abnormal_vibrissa_morphology | 0.59332710 |
| 87 | MP0005381_digestive/alimentary_phenotyp | 0.59265089 |
| 88 | MP0000604_amyloidosis | 0.58679395 |
| 89 | MP0002877_abnormal_melanocyte_morpholog | 0.57385622 |
| 90 | MP0003786_premature_aging | 0.55180576 |
| 91 | MP0002163_abnormal_gland_morphology | 0.53150635 |
| 92 | MP0000569_abnormal_digit_pigmentation | 0.51077864 |
| 93 | MP0006035_abnormal_mitochondrial_morpho | 0.48146057 |
| 94 | MP0001216_abnormal_epidermal_layer | 0.48009683 |
| 95 | MP0000858_altered_metastatic_potential | 0.47096167 |
| 96 | MP0000358_abnormal_cell_content/ | 0.46029906 |
| 97 | MP0002396_abnormal_hematopoietic_system | 0.45147706 |
| 98 | MP0002693_abnormal_pancreas_physiology | 0.43402667 |
| 99 | MP0002136_abnormal_kidney_physiology | 0.43367438 |
| 100 | MP0005464_abnormal_platelet_physiology | 0.41289656 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 4.93722631 |
| 2 | Slow saccadic eye movements (HP:0000514) | 4.93445780 |
| 3 | Arthropathy (HP:0003040) | 4.53008748 |
| 4 | T lymphocytopenia (HP:0005403) | 4.46456023 |
| 5 | Mediastinal lymphadenopathy (HP:0100721) | 4.29734731 |
| 6 | Abnormality of T cell number (HP:0011839) | 3.97755078 |
| 7 | Anhidrosis (HP:0000970) | 3.85000828 |
| 8 | Oligodactyly (hands) (HP:0001180) | 3.80788611 |
| 9 | Genetic anticipation (HP:0003743) | 3.65256924 |
| 10 | Orthostatic hypotension (HP:0001278) | 3.56923259 |
| 11 | Abnormality of the labia minora (HP:0012880) | 3.56769709 |
| 12 | Autoamputation (HP:0001218) | 3.47499423 |
| 13 | Recurrent corneal erosions (HP:0000495) | 3.38714893 |
| 14 | Episodic fever (HP:0001954) | 3.36598109 |
| 15 | Increased CSF protein (HP:0002922) | 3.33361059 |
| 16 | Clitoromegaly (HP:0000057) | 3.32654858 |
| 17 | Stomatitis (HP:0010280) | 3.26128113 |
| 18 | Abnormality of oral frenula (HP:0000190) | 3.22710085 |
| 19 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.20105225 |
| 20 | Supernumerary bones of the axial skeleton (HP:0009144) | 3.10235236 |
| 21 | Abnormality of T cells (HP:0002843) | 3.06777095 |
| 22 | Acute encephalopathy (HP:0006846) | 3.03133368 |
| 23 | Peripheral hypomyelination (HP:0007182) | 2.99567450 |
| 24 | Dysmetric saccades (HP:0000641) | 2.98940281 |
| 25 | Bifid tongue (HP:0010297) | 2.98487407 |
| 26 | Abnormality of midbrain morphology (HP:0002418) | 2.95950521 |
| 27 | Molar tooth sign on MRI (HP:0002419) | 2.95950521 |
| 28 | Chorioretinal atrophy (HP:0000533) | 2.93101996 |
| 29 | Dysautonomia (HP:0002459) | 2.92572828 |
| 30 | Short tibia (HP:0005736) | 2.91361692 |
| 31 | Ectopic kidney (HP:0000086) | 2.88370040 |
| 32 | Myositis (HP:0100614) | 2.86406619 |
| 33 | Abnormality of dental color (HP:0011073) | 2.79277157 |
| 34 | Abnormality of saccadic eye movements (HP:0000570) | 2.71001676 |
| 35 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.69593890 |
| 36 | Pulmonary infiltrates (HP:0002113) | 2.69433036 |
| 37 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.69232517 |
| 38 | Poor coordination (HP:0002370) | 2.68953431 |
| 39 | Volvulus (HP:0002580) | 2.68293430 |
| 40 | Tetraplegia (HP:0002445) | 2.66638487 |
| 41 | Chronic diarrhea (HP:0002028) | 2.64740842 |
| 42 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.58771906 |
| 43 | Scanning speech (HP:0002168) | 2.55918358 |
| 44 | Hemiplegia (HP:0002301) | 2.53962654 |
| 45 | Encephalitis (HP:0002383) | 2.52321288 |
| 46 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.50831966 |
| 47 | Recurrent cutaneous fungal infections (HP:0011370) | 2.50831966 |
| 48 | Supernumerary ribs (HP:0005815) | 2.49134999 |
| 49 | Abnormal biliary tract physiology (HP:0012439) | 2.44587259 |
| 50 | Bile duct proliferation (HP:0001408) | 2.44587259 |
| 51 | Neonatal respiratory distress (HP:0002643) | 2.43435334 |
| 52 | Hypoplastic nipples (HP:0002557) | 2.41527652 |
| 53 | Keratitis (HP:0000491) | 2.41203954 |
| 54 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.40372054 |
| 55 | Optic neuritis (HP:0100653) | 2.40345207 |
| 56 | Retrobulbar optic neuritis (HP:0100654) | 2.40345207 |
| 57 | Hypoproteinemia (HP:0003075) | 2.38395564 |
| 58 | Weak cry (HP:0001612) | 2.37025203 |
| 59 | Abnormality of DNA repair (HP:0003254) | 2.34221061 |
| 60 | IgM deficiency (HP:0002850) | 2.33950418 |
| 61 | Oligodactyly (HP:0012165) | 2.33815394 |
| 62 | Recurrent abscess formation (HP:0002722) | 2.30348004 |
| 63 | Progressive cerebellar ataxia (HP:0002073) | 2.27964339 |
| 64 | Abnormality of macrophages (HP:0004311) | 2.27695726 |
| 65 | Impaired vibratory sensation (HP:0002495) | 2.27668467 |
| 66 | Median cleft lip (HP:0000161) | 2.27025734 |
| 67 | Porencephaly (HP:0002132) | 2.24318943 |
| 68 | Albinism (HP:0001022) | 2.23910864 |
| 69 | Orchitis (HP:0100796) | 2.23903652 |
| 70 | Severe combined immunodeficiency (HP:0004430) | 2.23868851 |
| 71 | Hypotrichosis (HP:0001006) | 2.23618133 |
| 72 | Micronodular cirrhosis (HP:0001413) | 2.21488330 |
| 73 | Spastic paraparesis (HP:0002313) | 2.20875228 |
| 74 | Recurrent bacterial skin infections (HP:0005406) | 2.20841694 |
| 75 | Abnormality of the axillary hair (HP:0100134) | 2.19248000 |
| 76 | Abnormality of secondary sexual hair (HP:0009888) | 2.19248000 |
| 77 | Eczematoid dermatitis (HP:0000976) | 2.15421681 |
| 78 | Widely patent fontanelles and sutures (HP:0004492) | 2.14869605 |
| 79 | Recurrent fungal infections (HP:0002841) | 2.14200299 |
| 80 | IgG deficiency (HP:0004315) | 2.09390272 |
| 81 | Lymphopenia (HP:0001888) | 2.06395281 |
| 82 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.06233458 |
| 83 | Limb ataxia (HP:0002070) | 2.05024487 |
| 84 | Progressive muscle weakness (HP:0003323) | 2.03419201 |
| 85 | Abnormality of the clitoris (HP:0000056) | 2.02657007 |
| 86 | Tubular atrophy (HP:0000092) | 2.02175637 |
| 87 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.01896742 |
| 88 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.00404241 |
| 89 | Inflammation of the large intestine (HP:0002037) | 1.97752996 |
| 90 | Self-mutilation (HP:0000742) | 1.96577065 |
| 91 | Meningitis (HP:0001287) | 1.95955973 |
| 92 | Conjunctival hamartoma (HP:0100780) | 1.95366517 |
| 93 | Impaired proprioception (HP:0010831) | 1.93591280 |
| 94 | Recurrent skin infections (HP:0001581) | 1.91296093 |
| 95 | Cortical visual impairment (HP:0100704) | 1.90588680 |
| 96 | Abnormality of the renal cortex (HP:0011035) | 1.88763481 |
| 97 | Abnormality of T cell physiology (HP:0011840) | 1.88025786 |
| 98 | Thyroid carcinoma (HP:0002890) | 1.86164570 |
| 99 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.85915288 |
| 100 | Broad alveolar ridges (HP:0000187) | 1.83073631 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK1 | 5.75032217 |
| 2 | FES | 5.41159658 |
| 3 | MAP3K11 | 5.02455633 |
| 4 | TAOK2 | 4.80813208 |
| 5 | MAPKAPK3 | 4.65154064 |
| 6 | NTRK1 | 4.23485182 |
| 7 | NLK | 4.13014276 |
| 8 | MAP2K3 | 3.86688187 |
| 9 | MATK | 3.85233405 |
| 10 | MAP3K3 | 3.72493412 |
| 11 | MAP4K1 | 2.89203505 |
| 12 | CSK | 2.63022601 |
| 13 | MAP3K1 | 1.91467065 |
| 14 | MAP3K5 | 1.56372617 |
| 15 | ALK | 1.54356779 |
| 16 | TYRO3 | 1.50600135 |
| 17 | FER | 1.46710325 |
| 18 | TXK | 1.30764487 |
| 19 | ITK | 1.13006488 |
| 20 | DAPK1 | 1.06434713 |
| 21 | PINK1 | 0.94216123 |
| 22 | CSNK1G3 | 0.94134093 |
| 23 | LCK | 0.92872196 |
| 24 | CSNK1A1L | 0.91139158 |
| 25 | JAK3 | 0.86946716 |
| 26 | RIPK4 | 0.83686246 |
| 27 | HCK | 0.83670775 |
| 28 | TYK2 | 0.81186814 |
| 29 | ERBB2 | 0.80425950 |
| 30 | MARK3 | 0.80409115 |
| 31 | GRK6 | 0.79342277 |
| 32 | MAP4K2 | 0.78917171 |
| 33 | MAPKAPK2 | 0.74309240 |
| 34 | PASK | 0.73361385 |
| 35 | CSNK1G2 | 0.71648758 |
| 36 | PRKCQ | 0.71187595 |
| 37 | GRK7 | 0.71109844 |
| 38 | PHKG1 | 0.69273673 |
| 39 | PHKG2 | 0.69273673 |
| 40 | CSNK1G1 | 0.65847209 |
| 41 | MAP3K12 | 0.61983954 |
| 42 | BTK | 0.60694508 |
| 43 | LYN | 0.57870902 |
| 44 | PTK2B | 0.53972560 |
| 45 | STK10 | 0.50757402 |
| 46 | ERN1 | 0.50743628 |
| 47 | TLK1 | 0.50132515 |
| 48 | MAP3K8 | 0.48903997 |
| 49 | ZAP70 | 0.48761066 |
| 50 | EPHB1 | 0.48617759 |
| 51 | IRAK4 | 0.45369073 |
| 52 | SYK | 0.44520198 |
| 53 | MKNK2 | 0.43902234 |
| 54 | TNK2 | 0.43267063 |
| 55 | IKBKB | 0.41106015 |
| 56 | KIT | 0.39420614 |
| 57 | PRKD2 | 0.38018437 |
| 58 | ADRBK2 | 0.37976873 |
| 59 | INSR | 0.37757453 |
| 60 | TAOK3 | 0.37531384 |
| 61 | TGFBR2 | 0.37253316 |
| 62 | BLK | 0.37220825 |
| 63 | FGR | 0.35190478 |
| 64 | PDK1 | 0.34252527 |
| 65 | FYN | 0.34191666 |
| 66 | CASK | 0.32517613 |
| 67 | IKBKE | 0.30920862 |
| 68 | CAMKK1 | 0.30766837 |
| 69 | TEC | 0.29300240 |
| 70 | MAPK11 | 0.27402244 |
| 71 | JAK1 | 0.26708134 |
| 72 | JAK2 | 0.26438697 |
| 73 | PDK2 | 0.26037613 |
| 74 | PDGFRB | 0.25986210 |
| 75 | CSF1R | 0.25125815 |
| 76 | MAP3K14 | 0.24824115 |
| 77 | DMPK | 0.24681777 |
| 78 | MOS | 0.21444464 |
| 79 | MAP2K6 | 0.18855632 |
| 80 | BUB1 | 0.18686341 |
| 81 | RPS6KB1 | 0.16161337 |
| 82 | MAPK12 | 0.16040337 |
| 83 | SIK3 | 0.15147631 |
| 84 | GSK3A | 0.14167478 |
| 85 | NME1 | 0.14096029 |
| 86 | FGFR4 | 0.12548026 |
| 87 | CHUK | 0.10713157 |
| 88 | NUAK1 | 0.10306028 |
| 89 | IGF1R | 0.10189487 |
| 90 | PIM1 | 0.09765919 |
| 91 | CSNK2A1 | 0.08791351 |
| 92 | CHEK2 | 0.08738578 |
| 93 | TBK1 | 0.08728498 |
| 94 | CAMKK2 | 0.07483101 |
| 95 | PRKCH | 0.06691156 |
| 96 | NEK6 | 0.06252625 |
| 97 | GRK5 | 0.04874803 |
| 98 | PDPK1 | 0.04244201 |
| 99 | PTK6 | 0.03629388 |
| 100 | MARK2 | 0.02417984 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.93983502 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.66961423 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.54195379 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.50819975 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.42859107 |
| 6 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 3.32983279 |
| 7 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.06983933 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.86719050 |
| 9 | Thyroid cancer_Homo sapiens_hsa05216 | 2.80675797 |
| 10 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.75937033 |
| 11 | Renal cell carcinoma_Homo sapiens_hsa05211 | 2.40877583 |
| 12 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.39034691 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.22953001 |
| 14 | Malaria_Homo sapiens_hsa05144 | 2.06231134 |
| 15 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.89418765 |
| 16 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.85105836 |
| 17 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.83759499 |
| 18 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.73559677 |
| 19 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.63998842 |
| 20 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.63802202 |
| 21 | Measles_Homo sapiens_hsa05162 | 1.59402877 |
| 22 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.58655013 |
| 23 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.56239906 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52481886 |
| 25 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.45625613 |
| 26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.43808928 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.42429842 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.31546017 |
| 29 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.28018825 |
| 30 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.26823920 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.22137322 |
| 32 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.21988789 |
| 33 | Apoptosis_Homo sapiens_hsa04210 | 1.20881599 |
| 34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.20521739 |
| 35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.19388511 |
| 36 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.13214663 |
| 37 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.09890525 |
| 38 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.06579433 |
| 39 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.05916697 |
| 40 | MAPK signaling pathway_Homo sapiens_hsa04010 | 1.05071654 |
| 41 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.04101763 |
| 42 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.04083431 |
| 43 | Viral myocarditis_Homo sapiens_hsa05416 | 1.02045926 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.95525767 |
| 45 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.93712391 |
| 46 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.91544002 |
| 47 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.87790412 |
| 48 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.86238748 |
| 49 | Platelet activation_Homo sapiens_hsa04611 | 0.83265896 |
| 50 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.81816759 |
| 51 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.79512648 |
| 52 | HTLV-I infection_Homo sapiens_hsa05166 | 0.78049435 |
| 53 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.74180975 |
| 54 | Leishmaniasis_Homo sapiens_hsa05140 | 0.72935989 |
| 55 | Hepatitis B_Homo sapiens_hsa05161 | 0.62551307 |
| 56 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.60594935 |
| 57 | Proteasome_Homo sapiens_hsa03050 | 0.59361676 |
| 58 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.58510744 |
| 59 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.56260096 |
| 60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.56118335 |
| 61 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54763959 |
| 62 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.53051816 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45308479 |
| 64 | Spliceosome_Homo sapiens_hsa03040 | 0.44855835 |
| 65 | Colorectal cancer_Homo sapiens_hsa05210 | 0.44417836 |
| 66 | Endocytosis_Homo sapiens_hsa04144 | 0.42413849 |
| 67 | Purine metabolism_Homo sapiens_hsa00230 | 0.41205296 |
| 68 | Pathways in cancer_Homo sapiens_hsa05200 | 0.40944521 |
| 69 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.40933968 |
| 70 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39873437 |
| 71 | Tuberculosis_Homo sapiens_hsa05152 | 0.35625202 |
| 72 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.34265383 |
| 73 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.34246461 |
| 74 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.32875328 |
| 75 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.32472675 |
| 76 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.32406926 |
| 77 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.31526699 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.31321960 |
| 79 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.30288347 |
| 80 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30190980 |
| 81 | Influenza A_Homo sapiens_hsa05164 | 0.28169492 |
| 82 | Endometrial cancer_Homo sapiens_hsa05213 | 0.27941196 |
| 83 | Circadian rhythm_Homo sapiens_hsa04710 | 0.26770953 |
| 84 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.26666256 |
| 85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.26089490 |
| 86 | Adherens junction_Homo sapiens_hsa04520 | 0.26046083 |
| 87 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.25668762 |
| 88 | Mineral absorption_Homo sapiens_hsa04978 | 0.23186009 |
| 89 | RNA polymerase_Homo sapiens_hsa03020 | 0.22666037 |
| 90 | Histidine metabolism_Homo sapiens_hsa00340 | 0.21718086 |
| 91 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.21019646 |
| 92 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.20829051 |
| 93 | Morphine addiction_Homo sapiens_hsa05032 | 0.20196805 |
| 94 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.19119202 |
| 95 | Lysosome_Homo sapiens_hsa04142 | 0.17115569 |
| 96 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.16780733 |
| 97 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.16259451 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.16058486 |
| 99 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.15040136 |
| 100 | Legionellosis_Homo sapiens_hsa05134 | 0.14218175 |

