

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 6.89729257 |
| 2 | tolerance induction (GO:0002507) | 6.84771116 |
| 3 | negative regulation of cell killing (GO:0031342) | 6.68721611 |
| 4 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.68721611 |
| 5 | negative thymic T cell selection (GO:0045060) | 6.63228413 |
| 6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.47110431 |
| 7 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.44356579 |
| 8 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.38519009 |
| 9 | regulation of regulatory T cell differentiation (GO:0045589) | 6.32327829 |
| 10 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.95401975 |
| 11 | regulation of T cell tolerance induction (GO:0002664) | 5.87076264 |
| 12 | response to interleukin-15 (GO:0070672) | 5.72267305 |
| 13 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.68253287 |
| 14 | cellular response to interleukin-15 (GO:0071350) | 5.47236047 |
| 15 | thymic T cell selection (GO:0045061) | 5.46823904 |
| 16 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.44990904 |
| 17 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.42563478 |
| 18 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.36140294 |
| 19 | positive regulation of tolerance induction (GO:0002645) | 5.32511882 |
| 20 | T cell selection (GO:0045058) | 5.30717295 |
| 21 | positive T cell selection (GO:0043368) | 5.27389284 |
| 22 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.23101181 |
| 23 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.17905697 |
| 24 | regulation of tolerance induction (GO:0002643) | 4.93526839 |
| 25 | positive thymic T cell selection (GO:0045059) | 4.89673180 |
| 26 | regulation of gamma-delta T cell activation (GO:0046643) | 4.85026489 |
| 27 | activated T cell proliferation (GO:0050798) | 4.69791648 |
| 28 | negative regulation of T cell mediated immunity (GO:0002710) | 4.69698818 |
| 29 | T cell migration (GO:0072678) | 4.66154423 |
| 30 | leukocyte aggregation (GO:0070486) | 4.51141730 |
| 31 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.49489343 |
| 32 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.40811571 |
| 33 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.25529779 |
| 34 | T cell receptor signaling pathway (GO:0050852) | 4.16693896 |
| 35 | positive regulation of granulocyte differentiation (GO:0030854) | 4.04255571 |
| 36 | T cell homeostasis (GO:0043029) | 3.89652346 |
| 37 | regulation of B cell differentiation (GO:0045577) | 3.84323937 |
| 38 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.80855556 |
| 39 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.75040914 |
| 40 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.71800732 |
| 41 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.70382194 |
| 42 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.68250926 |
| 43 | alpha-beta T cell differentiation (GO:0046632) | 3.64196182 |
| 44 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.63238028 |
| 45 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.58824240 |
| 46 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.58824240 |
| 47 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.58706181 |
| 48 | positive regulation of interleukin-4 production (GO:0032753) | 3.57728732 |
| 49 | interferon-gamma production (GO:0032609) | 3.55736600 |
| 50 | Peyers patch development (GO:0048541) | 3.51087585 |
| 51 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.51087585 |
| 52 | positive regulation of isotype switching (GO:0045830) | 3.48661256 |
| 53 | regulation of isotype switching (GO:0045191) | 3.46263895 |
| 54 | positive regulation of interleukin-2 production (GO:0032743) | 3.46141615 |
| 55 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.44236036 |
| 56 | positive regulation of B cell differentiation (GO:0045579) | 3.42507061 |
| 57 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.39599374 |
| 58 | alpha-beta T cell activation (GO:0046631) | 3.35714175 |
| 59 | detection of bacterium (GO:0016045) | 3.34580512 |
| 60 | NIK/NF-kappaB signaling (GO:0038061) | 3.30981298 |
| 61 | mast cell activation (GO:0045576) | 3.27274237 |
| 62 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.24097141 |
| 63 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.23404396 |
| 64 | regulation of alpha-beta T cell activation (GO:0046634) | 3.23147737 |
| 65 | detection of other organism (GO:0098543) | 3.22028865 |
| 66 | T cell costimulation (GO:0031295) | 3.21924915 |
| 67 | positive regulation of macrophage differentiation (GO:0045651) | 3.21677089 |
| 68 | myeloid dendritic cell differentiation (GO:0043011) | 3.21628012 |
| 69 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.21251304 |
| 70 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.21251304 |
| 71 | modulation by symbiont of host immune response (GO:0052553) | 3.21251304 |
| 72 | positive regulation by symbiont of host defense response (GO:0052509) | 3.21251304 |
| 73 | modulation by symbiont of host defense response (GO:0052031) | 3.21251304 |
| 74 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.21251304 |
| 75 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.20182793 |
| 76 | positive regulation of interleukin-17 production (GO:0032740) | 3.17893102 |
| 77 | lymphocyte costimulation (GO:0031294) | 3.17458450 |
| 78 | regulation of interleukin-4 production (GO:0032673) | 3.17286515 |
| 79 | T cell differentiation (GO:0030217) | 3.17029098 |
| 80 | type I interferon signaling pathway (GO:0060337) | 3.13538940 |
| 81 | cellular response to type I interferon (GO:0071357) | 3.13538940 |
| 82 | lymphocyte homeostasis (GO:0002260) | 3.11882791 |
| 83 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.11540411 |
| 84 | response to type I interferon (GO:0034340) | 3.11367700 |
| 85 | positive regulation of DNA recombination (GO:0045911) | 3.10511001 |
| 86 | positive regulation of T cell mediated immunity (GO:0002711) | 3.10277396 |
| 87 | positive regulation of humoral immune response (GO:0002922) | 3.09452691 |
| 88 | natural killer cell differentiation (GO:0001779) | 3.08964737 |
| 89 | B cell receptor signaling pathway (GO:0050853) | 3.06823527 |
| 90 | lymphocyte migration (GO:0072676) | 3.06732512 |
| 91 | myeloid dendritic cell activation (GO:0001773) | 3.03428158 |
| 92 | negative regulation of interleukin-12 production (GO:0032695) | 3.03393347 |
| 93 | regulation of T cell mediated immunity (GO:0002709) | 3.02398243 |
| 94 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.02076993 |
| 95 | regulation of defense response to virus by virus (GO:0050690) | 3.01876062 |
| 96 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.01174568 |
| 97 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.98689360 |
| 98 | positive regulation of cell killing (GO:0031343) | 2.98541745 |
| 99 | positive regulation of alpha-beta T cell activation (GO:0046635) | 2.97140516 |
| 100 | regulation of cell killing (GO:0031341) | 2.96253075 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.51275872 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.37122599 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.42547405 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.18333834 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.85087137 |
| 6 | MYB_26560356_Chip-Seq_TH2_Human | 3.38221644 |
| 7 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.38007298 |
| 8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.36595035 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.20403112 |
| 10 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.99927187 |
| 11 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.98005630 |
| 12 | MAF_26560356_Chip-Seq_TH1_Human | 2.97366579 |
| 13 | MYC_22102868_ChIP-Seq_BL_Human | 2.94018120 |
| 14 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.93711762 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.88545664 |
| 16 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.86549482 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.76808512 |
| 18 | MYB_26560356_Chip-Seq_TH1_Human | 2.70178792 |
| 19 | UTX_26944678_Chip-Seq_JUKART_Human | 2.69225956 |
| 20 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.48663363 |
| 21 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.37768068 |
| 22 | MAF_26560356_Chip-Seq_TH2_Human | 2.37572583 |
| 23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.35934418 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.27521864 |
| 25 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.25680987 |
| 26 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.21587352 |
| 27 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.19623477 |
| 28 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.10085484 |
| 29 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.09971548 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.09025001 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.05754942 |
| 32 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.98104055 |
| 33 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.96909785 |
| 34 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.96244503 |
| 35 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.92855516 |
| 36 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.92591916 |
| 37 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.89128776 |
| 38 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.79010874 |
| 39 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.78740084 |
| 40 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.76872111 |
| 41 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.74499964 |
| 42 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73714003 |
| 43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69102451 |
| 44 | SPI1_23127762_ChIP-Seq_K562_Human | 1.67191906 |
| 45 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.65772740 |
| 46 | GATA3_26560356_Chip-Seq_TH2_Human | 1.60651279 |
| 47 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.58443930 |
| 48 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.55760560 |
| 49 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.47589976 |
| 50 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.46197398 |
| 51 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.43949996 |
| 52 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.43102152 |
| 53 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.40818595 |
| 54 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.38586610 |
| 55 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37283908 |
| 56 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.34522794 |
| 57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31658904 |
| 58 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.29843443 |
| 59 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.26337322 |
| 60 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25635650 |
| 61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.25628623 |
| 62 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.25465055 |
| 63 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.21832882 |
| 64 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.21732125 |
| 65 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.16360651 |
| 66 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15769884 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13130517 |
| 68 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.13075077 |
| 69 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11030868 |
| 70 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.10341001 |
| 71 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08927952 |
| 72 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06999833 |
| 73 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.05270287 |
| 74 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.02997236 |
| 75 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.99764324 |
| 76 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.98124166 |
| 77 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97269400 |
| 78 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.96755969 |
| 79 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.95691072 |
| 80 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.94960975 |
| 81 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.94789903 |
| 82 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.92072999 |
| 83 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91876849 |
| 84 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91449590 |
| 85 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90860757 |
| 86 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88040535 |
| 87 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.87579673 |
| 88 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.87037427 |
| 89 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.86676721 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82024004 |
| 91 | GATA1_19941826_ChIP-Seq_K562_Human | 0.80200311 |
| 92 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.79502133 |
| 93 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.79285104 |
| 94 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.79003640 |
| 95 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.77767275 |
| 96 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.77130248 |
| 97 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.76075304 |
| 98 | GATA3_26560356_Chip-Seq_TH1_Human | 0.74001147 |
| 99 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.73712335 |
| 100 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.66719120 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 5.35869984 |
| 2 | MP0005671_abnormal_response_to | 4.32949141 |
| 3 | MP0003436_decreased_susceptibility_to | 3.93842455 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.53298242 |
| 5 | MP0001873_stomach_inflammation | 3.35809612 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 3.28345193 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.19843047 |
| 8 | MP0001800_abnormal_humoral_immune | 3.17835550 |
| 9 | MP0005387_immune_system_phenotype | 3.09753806 |
| 10 | MP0001790_abnormal_immune_system | 3.09753806 |
| 11 | MP0003300_gastrointestinal_ulcer | 3.06527095 |
| 12 | MP0003724_increased_susceptibility_to | 2.93737493 |
| 13 | MP0000685_abnormal_immune_system | 2.83563672 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.74852790 |
| 15 | MP0001819_abnormal_immune_cell | 2.70744991 |
| 16 | MP0002723_abnormal_immune_serum | 2.69713083 |
| 17 | MP0000703_abnormal_thymus_morphology | 2.62956496 |
| 18 | MP0003866_abnormal_defecation | 2.61121166 |
| 19 | MP0002405_respiratory_system_inflammati | 2.54649156 |
| 20 | MP0005025_abnormal_response_to | 2.54392057 |
| 21 | MP0000465_gastrointestinal_hemorrhage | 2.52245112 |
| 22 | MP0002398_abnormal_bone_marrow | 2.48554368 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 2.44275594 |
| 24 | MP0002452_abnormal_antigen_presenting | 2.42747834 |
| 25 | MP0006082_CNS_inflammation | 2.40982708 |
| 26 | MP0009785_altered_susceptibility_to | 2.34600138 |
| 27 | MP0010155_abnormal_intestine_physiology | 2.30854820 |
| 28 | MP0002419_abnormal_innate_immunity | 2.28370974 |
| 29 | MP0000716_abnormal_immune_system | 2.23752404 |
| 30 | MP0004381_abnormal_hair_follicle | 2.12041582 |
| 31 | MP0002722_abnormal_immune_system | 2.05169639 |
| 32 | MP0004947_skin_inflammation | 1.99283872 |
| 33 | MP0003303_peritoneal_inflammation | 1.98404233 |
| 34 | MP0000689_abnormal_spleen_morphology | 1.95263238 |
| 35 | MP0002277_abnormal_respiratory_mucosa | 1.92151904 |
| 36 | MP0001348_abnormal_lacrimal_gland | 1.77970648 |
| 37 | MP0002429_abnormal_blood_cell | 1.76180516 |
| 38 | MP0005310_abnormal_salivary_gland | 1.76066688 |
| 39 | MP0005464_abnormal_platelet_physiology | 1.74396240 |
| 40 | MP0001853_heart_inflammation | 1.74036122 |
| 41 | MP0001845_abnormal_inflammatory_respons | 1.66760510 |
| 42 | MP0001533_abnormal_skeleton_physiology | 1.57248531 |
| 43 | MP0002166_altered_tumor_susceptibility | 1.53575118 |
| 44 | MP0001851_eye_inflammation | 1.53204082 |
| 45 | MP0002396_abnormal_hematopoietic_system | 1.50263396 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.43058472 |
| 47 | MP0002933_joint_inflammation | 1.34124400 |
| 48 | MP0000490_abnormal_crypts_of | 1.33104647 |
| 49 | MP0002132_abnormal_respiratory_system | 1.30566476 |
| 50 | MP0008260_abnormal_autophagy | 1.18627035 |
| 51 | MP0008469_abnormal_protein_level | 1.13253949 |
| 52 | MP0002163_abnormal_gland_morphology | 1.04990997 |
| 53 | MP0002009_preneoplasia | 1.02981863 |
| 54 | MP0000858_altered_metastatic_potential | 0.98316681 |
| 55 | MP0002006_tumorigenesis | 0.96062499 |
| 56 | MP0002998_abnormal_bone_remodeling | 0.94519587 |
| 57 | MP0000604_amyloidosis | 0.93885713 |
| 58 | MP0001663_abnormal_digestive_system | 0.91462061 |
| 59 | MP0002138_abnormal_hepatobiliary_system | 0.87755061 |
| 60 | MP0005451_abnormal_body_composition | 0.86694730 |
| 61 | MP0009278_abnormal_bone_marrow | 0.83422037 |
| 62 | MP0004808_abnormal_hematopoietic_stem | 0.81604188 |
| 63 | MP0002019_abnormal_tumor_incidence | 0.78345824 |
| 64 | MP0003172_abnormal_lysosome_physiology | 0.78193311 |
| 65 | MP0003045_fibrosis | 0.74283325 |
| 66 | MP0003191_abnormal_cellular_cholesterol | 0.72807139 |
| 67 | MP0002254_reproductive_system_inflammat | 0.72674040 |
| 68 | MP0009763_increased_sensitivity_to | 0.69977453 |
| 69 | MP0009764_decreased_sensitivity_to | 0.68232854 |
| 70 | MP0002693_abnormal_pancreas_physiology | 0.67319731 |
| 71 | MP0003448_altered_tumor_morphology | 0.67258497 |
| 72 | MP0003828_pulmonary_edema | 0.65618953 |
| 73 | MP0008569_lethality_at_weaning | 0.64795367 |
| 74 | MP0004510_myositis | 0.63293194 |
| 75 | MP0008961_abnormal_basal_metabolism | 0.60838856 |
| 76 | MP0005390_skeleton_phenotype | 0.56179383 |
| 77 | MP0001919_abnormal_reproductive_system | 0.56123261 |
| 78 | MP0005166_decreased_susceptibility_to | 0.52703856 |
| 79 | MP0003795_abnormal_bone_structure | 0.51769515 |
| 80 | MP0004130_abnormal_muscle_cell | 0.51696180 |
| 81 | MP0001346_abnormal_lacrimal_gland | 0.51294480 |
| 82 | MP0004883_abnormal_blood_vessel | 0.49610812 |
| 83 | MP0000249_abnormal_blood_vessel | 0.49371838 |
| 84 | MP0000609_abnormal_liver_physiology | 0.48426380 |
| 85 | MP0003786_premature_aging | 0.48181856 |
| 86 | MP0005381_digestive/alimentary_phenotyp | 0.47456445 |
| 87 | MP0003091_abnormal_cell_migration | 0.45793365 |
| 88 | MP0008004_abnormal_stomach_pH | 0.43889194 |
| 89 | MP0009765_abnormal_xenobiotic_induced | 0.40936650 |
| 90 | MP0000920_abnormal_myelination | 0.40468858 |
| 91 | MP0000015_abnormal_ear_pigmentation | 0.39477162 |
| 92 | MP0000477_abnormal_intestine_morphology | 0.38992392 |
| 93 | MP0008873_increased_physiological_sensi | 0.38080603 |
| 94 | MP0005379_endocrine/exocrine_gland_phen | 0.34138846 |
| 95 | MP0001986_abnormal_taste_sensitivity | 0.33366271 |
| 96 | MP0003075_altered_response_to | 0.31909408 |
| 97 | MP0001502_abnormal_circadian_rhythm | 0.31222602 |
| 98 | MP0001765_abnormal_ion_homeostasis | 0.30919310 |
| 99 | MP0008874_decreased_physiological_sensi | 0.30792552 |
| 100 | MP0002083_premature_death | 0.29269450 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune hemolytic anemia (HP:0001890) | 6.54430913 |
| 2 | Stomatitis (HP:0010280) | 6.43628548 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.96991253 |
| 4 | Eczematoid dermatitis (HP:0000976) | 5.84145408 |
| 5 | T lymphocytopenia (HP:0005403) | 5.73271170 |
| 6 | Abnormality of T cell number (HP:0011839) | 5.41353074 |
| 7 | Myositis (HP:0100614) | 4.72850848 |
| 8 | Abnormality of T cells (HP:0002843) | 4.72380078 |
| 9 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.56333725 |
| 10 | Recurrent fungal infections (HP:0002841) | 4.28100589 |
| 11 | Severe combined immunodeficiency (HP:0004430) | 4.21004576 |
| 12 | Gastrointestinal infarctions (HP:0005244) | 4.19152600 |
| 13 | Recurrent abscess formation (HP:0002722) | 4.09761176 |
| 14 | Recurrent bacterial skin infections (HP:0005406) | 4.09399795 |
| 15 | Orchitis (HP:0100796) | 3.85992056 |
| 16 | Abnormality of macrophages (HP:0004311) | 3.84732397 |
| 17 | Abnormality of T cell physiology (HP:0011840) | 3.84674192 |
| 18 | Vasculitis (HP:0002633) | 3.82044644 |
| 19 | Optic neuritis (HP:0100653) | 3.78770916 |
| 20 | Retrobulbar optic neuritis (HP:0100654) | 3.78770916 |
| 21 | Panhypogammaglobulinemia (HP:0003139) | 3.75803557 |
| 22 | Meningitis (HP:0001287) | 3.71998455 |
| 23 | Chronic obstructive pulmonary disease (HP:0006510) | 3.70469297 |
| 24 | Obstructive lung disease (HP:0006536) | 3.70469297 |
| 25 | IgG deficiency (HP:0004315) | 3.69380958 |
| 26 | Lymphopenia (HP:0001888) | 3.67212735 |
| 27 | Pustule (HP:0200039) | 3.66690068 |
| 28 | Mediastinal lymphadenopathy (HP:0100721) | 3.64410907 |
| 29 | Increased IgM level (HP:0003496) | 3.60786680 |
| 30 | Granulocytopenia (HP:0001913) | 3.60020025 |
| 31 | Recurrent viral infections (HP:0004429) | 3.57280379 |
| 32 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.55939144 |
| 33 | Recurrent cutaneous fungal infections (HP:0011370) | 3.55939144 |
| 34 | Encephalitis (HP:0002383) | 3.47824749 |
| 35 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.47088593 |
| 36 | Abnormality of eosinophils (HP:0001879) | 3.41834785 |
| 37 | Spontaneous hematomas (HP:0007420) | 3.41530497 |
| 38 | Leukocytosis (HP:0001974) | 3.34203086 |
| 39 | Combined immunodeficiency (HP:0005387) | 3.31043572 |
| 40 | Autoimmune thrombocytopenia (HP:0001973) | 3.30771354 |
| 41 | Eosinophilia (HP:0001880) | 3.29809707 |
| 42 | IgM deficiency (HP:0002850) | 3.26370364 |
| 43 | Increased IgE level (HP:0003212) | 3.25716041 |
| 44 | Pulmonary infiltrates (HP:0002113) | 3.22090221 |
| 45 | Chest pain (HP:0100749) | 3.21368804 |
| 46 | Recurrent skin infections (HP:0001581) | 3.12792506 |
| 47 | Recurrent bronchitis (HP:0002837) | 3.05556045 |
| 48 | Chronic diarrhea (HP:0002028) | 2.96902468 |
| 49 | Hypochromic anemia (HP:0001931) | 2.93014360 |
| 50 | Prolonged bleeding time (HP:0003010) | 2.89561243 |
| 51 | Hypochromic microcytic anemia (HP:0004840) | 2.86091190 |
| 52 | Keratoconjunctivitis (HP:0001096) | 2.83349009 |
| 53 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.82694090 |
| 54 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.80631341 |
| 55 | Keratoconjunctivitis sicca (HP:0001097) | 2.79554509 |
| 56 | Hemoptysis (HP:0002105) | 2.74976834 |
| 57 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.63232753 |
| 58 | Lymphoma (HP:0002665) | 2.61120368 |
| 59 | Papilloma (HP:0012740) | 2.58821231 |
| 60 | Verrucae (HP:0200043) | 2.58821231 |
| 61 | Joint swelling (HP:0001386) | 2.57352367 |
| 62 | Inflammation of the large intestine (HP:0002037) | 2.57307068 |
| 63 | Pulmonary embolism (HP:0002204) | 2.57012853 |
| 64 | Gastrointestinal inflammation (HP:0004386) | 2.55476272 |
| 65 | Epistaxis (HP:0000421) | 2.54643196 |
| 66 | Papilledema (HP:0001085) | 2.50511658 |
| 67 | Increased cerebral lipofuscin (HP:0011813) | 2.50036208 |
| 68 | Gingivitis (HP:0000230) | 2.47771168 |
| 69 | Agammaglobulinemia (HP:0004432) | 2.46453985 |
| 70 | Hypergammaglobulinemia (HP:0010702) | 2.44496065 |
| 71 | Basal cell carcinoma (HP:0002671) | 2.44315023 |
| 72 | Urticaria (HP:0001025) | 2.42774357 |
| 73 | Hypoplasia of the thymus (HP:0000778) | 2.36604207 |
| 74 | Abnormality of the prostate (HP:0008775) | 2.36320241 |
| 75 | Gangrene (HP:0100758) | 2.34266029 |
| 76 | Anorexia (HP:0002039) | 2.25852715 |
| 77 | Slow saccadic eye movements (HP:0000514) | 2.21874665 |
| 78 | Thyroiditis (HP:0100646) | 2.17371325 |
| 79 | Alveolar cell carcinoma (HP:0006519) | 2.16138271 |
| 80 | Microcytic anemia (HP:0001935) | 2.14425596 |
| 81 | Abnormality of the pleura (HP:0002103) | 2.12922017 |
| 82 | Sepsis (HP:0100806) | 2.11157487 |
| 83 | Petechiae (HP:0000967) | 2.10818229 |
| 84 | Cellulitis (HP:0100658) | 2.02913977 |
| 85 | Glomerulopathy (HP:0100820) | 2.02898631 |
| 86 | Arterial thrombosis (HP:0004420) | 2.00023239 |
| 87 | Acute hepatic failure (HP:0006554) | 1.98561265 |
| 88 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.98256586 |
| 89 | Gingival bleeding (HP:0000225) | 1.95458808 |
| 90 | Colitis (HP:0002583) | 1.93896513 |
| 91 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.91776408 |
| 92 | Abnormality of B cell number (HP:0010975) | 1.91773412 |
| 93 | Episodic fever (HP:0001954) | 1.89260208 |
| 94 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.88552637 |
| 95 | B lymphocytopenia (HP:0010976) | 1.88360104 |
| 96 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.87945052 |
| 97 | Skin ulcer (HP:0200042) | 1.86418474 |
| 98 | Amaurosis fugax (HP:0100576) | 1.84204634 |
| 99 | Skin rash (HP:0000988) | 1.80238156 |
| 100 | Purpura (HP:0000979) | 1.78479015 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.71169361 |
| 2 | TXK | 5.63517321 |
| 3 | ITK | 2.91169727 |
| 4 | ZAP70 | 2.64941226 |
| 5 | RIPK4 | 2.61139436 |
| 6 | FES | 2.56858986 |
| 7 | PRPF4B | 2.52150273 |
| 8 | CSK | 2.46553300 |
| 9 | BTK | 2.34862092 |
| 10 | GRK6 | 2.22296144 |
| 11 | PASK | 2.21513108 |
| 12 | TYK2 | 2.16171136 |
| 13 | JAK3 | 1.98971372 |
| 14 | SIK3 | 1.95444690 |
| 15 | LCK | 1.91064875 |
| 16 | TNK2 | 1.89717756 |
| 17 | IRAK4 | 1.82850570 |
| 18 | IKBKE | 1.76222549 |
| 19 | HCK | 1.70779337 |
| 20 | NLK | 1.68598325 |
| 21 | SYK | 1.64004219 |
| 22 | MAP3K13 | 1.63063467 |
| 23 | EPHB1 | 1.58217613 |
| 24 | TEC | 1.57388523 |
| 25 | CAMKK2 | 1.57063160 |
| 26 | CAMKK1 | 1.55957568 |
| 27 | FGFR4 | 1.50355805 |
| 28 | MAP3K14 | 1.45390790 |
| 29 | ERN1 | 1.44857369 |
| 30 | JAK1 | 1.43758018 |
| 31 | MARK3 | 1.42626056 |
| 32 | MAP2K3 | 1.38633960 |
| 33 | MAP3K11 | 1.34161709 |
| 34 | TBK1 | 1.32097667 |
| 35 | LYN | 1.26743581 |
| 36 | SIK2 | 1.24181219 |
| 37 | BLK | 1.19565174 |
| 38 | TAOK3 | 1.16516311 |
| 39 | IKBKB | 1.12703896 |
| 40 | PRKCQ | 1.11127069 |
| 41 | MAP3K1 | 1.08888867 |
| 42 | JAK2 | 1.08268526 |
| 43 | MAP3K3 | 1.06396450 |
| 44 | FGFR3 | 1.01256527 |
| 45 | MAP3K10 | 0.95248461 |
| 46 | STK10 | 0.91631966 |
| 47 | TYRO3 | 0.90171503 |
| 48 | TAOK1 | 0.88832018 |
| 49 | KDR | 0.84071213 |
| 50 | MAPK12 | 0.82666394 |
| 51 | PDK1 | 0.77392300 |
| 52 | HIPK2 | 0.76556822 |
| 53 | CDK12 | 0.74502095 |
| 54 | LRRK2 | 0.74436378 |
| 55 | TAOK2 | 0.74140684 |
| 56 | SMG1 | 0.73771090 |
| 57 | CSF1R | 0.71567180 |
| 58 | FYN | 0.71085704 |
| 59 | TESK2 | 0.70917244 |
| 60 | EPHA3 | 0.69860997 |
| 61 | PTK6 | 0.66779992 |
| 62 | SIK1 | 0.65002331 |
| 63 | MAPK11 | 0.63988204 |
| 64 | MARK2 | 0.63822029 |
| 65 | CDK4 | 0.62195147 |
| 66 | PIM1 | 0.62122755 |
| 67 | MAP3K7 | 0.60687872 |
| 68 | TRIB3 | 0.59660632 |
| 69 | PRKD2 | 0.58961170 |
| 70 | YES1 | 0.55453266 |
| 71 | KSR2 | 0.54577231 |
| 72 | PRKCH | 0.53148229 |
| 73 | PDGFRB | 0.52246704 |
| 74 | FGR | 0.52183411 |
| 75 | MAPK7 | 0.51589732 |
| 76 | BMPR2 | 0.50279634 |
| 77 | IRAK1 | 0.41829531 |
| 78 | CDK6 | 0.40194407 |
| 79 | STK38 | 0.38657128 |
| 80 | CDK19 | 0.38363187 |
| 81 | RET | 0.38109497 |
| 82 | CLK1 | 0.36180524 |
| 83 | DYRK1B | 0.35015742 |
| 84 | MAP2K6 | 0.34331090 |
| 85 | NEK6 | 0.33987364 |
| 86 | PKN2 | 0.33386413 |
| 87 | PDPK1 | 0.31534366 |
| 88 | MAPKAPK2 | 0.31359517 |
| 89 | UHMK1 | 0.29383086 |
| 90 | MAPK3 | 0.27398699 |
| 91 | NTRK2 | 0.27113645 |
| 92 | SGK3 | 0.26439847 |
| 93 | BRD4 | 0.25971913 |
| 94 | RPS6KB1 | 0.24546192 |
| 95 | FGFR1 | 0.23909290 |
| 96 | MELK | 0.23516318 |
| 97 | INSR | 0.23436393 |
| 98 | CHUK | 0.23064855 |
| 99 | IRAK2 | 0.21168386 |
| 100 | EGFR | 0.19326360 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.42734204 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.69685865 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.90343445 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.89637355 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.84304017 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.81616965 |
| 7 | Measles_Homo sapiens_hsa05162 | 2.65560027 |
| 8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.42325826 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.35947040 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.19685276 |
| 11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.11723549 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.06103870 |
| 13 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 2.00947508 |
| 14 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.93125095 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.92969185 |
| 16 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.82946939 |
| 17 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.81810646 |
| 18 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.81238954 |
| 19 | Leishmaniasis_Homo sapiens_hsa05140 | 1.73392115 |
| 20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.72796263 |
| 21 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.68913134 |
| 22 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.56343936 |
| 23 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.53461320 |
| 24 | Viral myocarditis_Homo sapiens_hsa05416 | 1.53197969 |
| 25 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.46012714 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.44504757 |
| 27 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.42602255 |
| 28 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.42254277 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.42180670 |
| 30 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.41512664 |
| 31 | Hepatitis B_Homo sapiens_hsa05161 | 1.31867807 |
| 32 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.25357497 |
| 33 | Tuberculosis_Homo sapiens_hsa05152 | 1.16160005 |
| 34 | Malaria_Homo sapiens_hsa05144 | 1.15433947 |
| 35 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.15346831 |
| 36 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.14361634 |
| 37 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.12483754 |
| 38 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.10937833 |
| 39 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.10689078 |
| 40 | HTLV-I infection_Homo sapiens_hsa05166 | 1.10204698 |
| 41 | Influenza A_Homo sapiens_hsa05164 | 1.08802580 |
| 42 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.06388352 |
| 43 | Apoptosis_Homo sapiens_hsa04210 | 1.03882575 |
| 44 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.03169676 |
| 45 | Colorectal cancer_Homo sapiens_hsa05210 | 0.98774301 |
| 46 | Platelet activation_Homo sapiens_hsa04611 | 0.96876669 |
| 47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.92813834 |
| 48 | Hepatitis C_Homo sapiens_hsa05160 | 0.92385714 |
| 49 | Shigellosis_Homo sapiens_hsa05131 | 0.87162996 |
| 50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.86713832 |
| 51 | Legionellosis_Homo sapiens_hsa05134 | 0.86524603 |
| 52 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.85804040 |
| 53 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.84828630 |
| 54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.84713706 |
| 55 | Endometrial cancer_Homo sapiens_hsa05213 | 0.84409659 |
| 56 | Asthma_Homo sapiens_hsa05310 | 0.83705641 |
| 57 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.83383511 |
| 58 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.82503755 |
| 59 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79793436 |
| 60 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.76422122 |
| 61 | Salmonella infection_Homo sapiens_hsa05132 | 0.74863241 |
| 62 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.74703199 |
| 63 | Endocytosis_Homo sapiens_hsa04144 | 0.71840324 |
| 64 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.71188805 |
| 65 | Thyroid cancer_Homo sapiens_hsa05216 | 0.70192517 |
| 66 | Pertussis_Homo sapiens_hsa05133 | 0.60031656 |
| 67 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.59849894 |
| 68 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.58717637 |
| 69 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.55741318 |
| 70 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55513283 |
| 71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.54492484 |
| 72 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.53038428 |
| 73 | Prostate cancer_Homo sapiens_hsa05215 | 0.51993702 |
| 74 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51705216 |
| 75 | Long-term potentiation_Homo sapiens_hsa04720 | 0.50763678 |
| 76 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.50698096 |
| 77 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.49124778 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47991211 |
| 79 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.47363896 |
| 80 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.46127135 |
| 81 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.45163939 |
| 82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.43888027 |
| 83 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.43659833 |
| 84 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.40304051 |
| 85 | Phagosome_Homo sapiens_hsa04145 | 0.38380738 |
| 86 | Ribosome_Homo sapiens_hsa03010 | 0.38201252 |
| 87 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.37214073 |
| 88 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.37024295 |
| 89 | Insulin resistance_Homo sapiens_hsa04931 | 0.36241321 |
| 90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.35431394 |
| 91 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.34154237 |
| 92 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.32978247 |
| 93 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32886029 |
| 94 | Glioma_Homo sapiens_hsa05214 | 0.32282234 |
| 95 | Other glycan degradation_Homo sapiens_hsa00511 | 0.30491454 |
| 96 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.29600499 |
| 97 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.27259272 |
| 98 | Spliceosome_Homo sapiens_hsa03040 | 0.26948062 |
| 99 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.26747689 |
| 100 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.24782906 |

