

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine metabolic process (GO:0046087) | 8.98075827 |
| 2 | cytidine catabolic process (GO:0006216) | 8.98075827 |
| 3 | cytidine deamination (GO:0009972) | 8.98075827 |
| 4 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 8.14408503 |
| 5 | DNA deamination (GO:0045006) | 7.00617597 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.20016129 |
| 7 | negative regulation of cAMP-mediated signaling (GO:0043951) | 5.85803411 |
| 8 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.63005202 |
| 9 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.62021601 |
| 10 | negative T cell selection (GO:0043383) | 5.40521055 |
| 11 | cellular response to interleukin-15 (GO:0071350) | 5.38884101 |
| 12 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 5.36580275 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.03608061 |
| 14 | opioid receptor signaling pathway (GO:0038003) | 4.89297149 |
| 15 | response to interleukin-15 (GO:0070672) | 4.78943809 |
| 16 | negative thymic T cell selection (GO:0045060) | 4.74094271 |
| 17 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.51074907 |
| 18 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 4.49989594 |
| 19 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.48793505 |
| 20 | negative regulation of cell killing (GO:0031342) | 4.48793505 |
| 21 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.44594444 |
| 22 | T cell migration (GO:0072678) | 4.41044408 |
| 23 | regulation of regulatory T cell differentiation (GO:0045589) | 4.30697679 |
| 24 | positive T cell selection (GO:0043368) | 4.28987411 |
| 25 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.27134533 |
| 26 | regulation of T cell tolerance induction (GO:0002664) | 4.23254975 |
| 27 | regulation of gamma-delta T cell activation (GO:0046643) | 4.17578056 |
| 28 | positive regulation of B cell differentiation (GO:0045579) | 4.17140897 |
| 29 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.10491811 |
| 30 | thymic T cell selection (GO:0045061) | 4.09705545 |
| 31 | signal complex assembly (GO:0007172) | 4.06065536 |
| 32 | positive regulation of tolerance induction (GO:0002645) | 4.04351140 |
| 33 | regulation of B cell differentiation (GO:0045577) | 4.03290535 |
| 34 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 4.01282319 |
| 35 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 4.00436868 |
| 36 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.99014494 |
| 37 | T cell selection (GO:0045058) | 3.94261749 |
| 38 | regulation of acrosome reaction (GO:0060046) | 3.90786105 |
| 39 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.89694498 |
| 40 | positive thymic T cell selection (GO:0045059) | 3.88600631 |
| 41 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.86101756 |
| 42 | negative regulation by host of viral transcription (GO:0043922) | 3.80705859 |
| 43 | mast cell activation (GO:0045576) | 3.75853437 |
| 44 | positive regulation of defense response to virus by host (GO:0002230) | 3.75627123 |
| 45 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.73913104 |
| 46 | regulation of translational termination (GO:0006449) | 3.68750075 |
| 47 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.68642941 |
| 48 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.66126248 |
| 49 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.66052433 |
| 50 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.64690542 |
| 51 | thrombin receptor signaling pathway (GO:0070493) | 3.57870329 |
| 52 | regulation of tolerance induction (GO:0002643) | 3.57289751 |
| 53 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.55746597 |
| 54 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.53533330 |
| 55 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.51642550 |
| 56 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.50009195 |
| 57 | adult feeding behavior (GO:0008343) | 3.45426736 |
| 58 | positive regulation of interleukin-1 secretion (GO:0050716) | 3.44767849 |
| 59 | ether lipid metabolic process (GO:0046485) | 3.43967916 |
| 60 | negative regulation of T cell apoptotic process (GO:0070233) | 3.43755288 |
| 61 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.43536143 |
| 62 | activated T cell proliferation (GO:0050798) | 3.41213352 |
| 63 | negative regulation of viral genome replication (GO:0045071) | 3.40850062 |
| 64 | leukocyte aggregation (GO:0070486) | 3.40030917 |
| 65 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.39831573 |
| 66 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.39227051 |
| 67 | tolerance induction (GO:0002507) | 3.37650220 |
| 68 | positive regulation of humoral immune response (GO:0002922) | 3.33356628 |
| 69 | behavioral response to ethanol (GO:0048149) | 3.25788109 |
| 70 | lymphocyte chemotaxis (GO:0048247) | 3.25224450 |
| 71 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.24170722 |
| 72 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.23975106 |
| 73 | regulation of interleukin-1 secretion (GO:0050704) | 3.21602208 |
| 74 | T cell receptor signaling pathway (GO:0050852) | 3.19153431 |
| 75 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.17929863 |
| 76 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.14306747 |
| 77 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.12587663 |
| 78 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.12255605 |
| 79 | piRNA metabolic process (GO:0034587) | 3.09651493 |
| 80 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.07551506 |
| 81 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.07514132 |
| 82 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.06724013 |
| 83 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.06724013 |
| 84 | lymph node development (GO:0048535) | 3.04833197 |
| 85 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.02831704 |
| 86 | positive regulation of cell killing (GO:0031343) | 3.01140053 |
| 87 | regulation of memory T cell differentiation (GO:0043380) | 3.00798955 |
| 88 | regulation of interleukin-8 secretion (GO:2000482) | 2.99221145 |
| 89 | positive regulation of interleukin-1 beta production (GO:0032731) | 2.97731462 |
| 90 | negative regulation of T cell mediated immunity (GO:0002710) | 2.97613742 |
| 91 | regulation of defense response to virus by host (GO:0050691) | 2.96519701 |
| 92 | eosinophil chemotaxis (GO:0048245) | 2.96107442 |
| 93 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.92604131 |
| 94 | cellular defense response (GO:0006968) | 2.91099148 |
| 95 | immunoglobulin mediated immune response (GO:0016064) | 2.88728475 |
| 96 | negative regulation of viral transcription (GO:0032897) | 2.88610699 |
| 97 | T cell costimulation (GO:0031295) | 2.87561518 |
| 98 | lymphocyte migration (GO:0072676) | 2.87040307 |
| 99 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.85059948 |
| 100 | lymphocyte costimulation (GO:0031294) | 2.83693640 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 8.73332094 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.97353959 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.49676951 |
| 4 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.28376668 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.76008986 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.55953813 |
| 7 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.51595277 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.04012777 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 2.86296578 |
| 10 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.57672919 |
| 11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.51083828 |
| 12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.50885656 |
| 13 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.42844048 |
| 14 | MYB_26560356_Chip-Seq_TH1_Human | 2.41707215 |
| 15 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.34714082 |
| 16 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.32247194 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.25146376 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.17520669 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.17414626 |
| 20 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.08016929 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.00135519 |
| 22 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.86338547 |
| 23 | UTX_26944678_Chip-Seq_JUKART_Human | 1.85793823 |
| 24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.81308363 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.79632250 |
| 26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.73690147 |
| 27 | GATA3_26560356_Chip-Seq_TH2_Human | 1.73420270 |
| 28 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.71326921 |
| 29 | MAF_26560356_Chip-Seq_TH2_Human | 1.62661012 |
| 30 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60491361 |
| 31 | MAF_26560356_Chip-Seq_TH1_Human | 1.59934239 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.56149694 |
| 33 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.54822645 |
| 34 | RXR_22108803_ChIP-Seq_LS180_Human | 1.50659924 |
| 35 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.46042912 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.44442316 |
| 37 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37163194 |
| 38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.33020917 |
| 39 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.28457663 |
| 40 | SPI1_23127762_ChIP-Seq_K562_Human | 1.25633785 |
| 41 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.24401996 |
| 42 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24164555 |
| 43 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.21261092 |
| 44 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.19761893 |
| 45 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.17909255 |
| 46 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.16867820 |
| 47 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.16120984 |
| 48 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.15738938 |
| 49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.14813200 |
| 50 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.14726408 |
| 51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.14386632 |
| 52 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13594922 |
| 53 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.10375209 |
| 54 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09786548 |
| 55 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.08317200 |
| 56 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.08282457 |
| 57 | GATA3_26560356_Chip-Seq_TH1_Human | 1.07097456 |
| 58 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.04091198 |
| 59 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.04052708 |
| 60 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.03742345 |
| 61 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.02735321 |
| 62 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.02679647 |
| 63 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.00617176 |
| 64 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.97871937 |
| 65 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.95087251 |
| 66 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94799651 |
| 67 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.94125683 |
| 68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.90864404 |
| 69 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.90332933 |
| 70 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.90299221 |
| 71 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.90055348 |
| 72 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.90009850 |
| 73 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.89455537 |
| 74 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.88601707 |
| 75 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.87923396 |
| 76 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.87574418 |
| 77 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.86454088 |
| 78 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.86286233 |
| 79 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.86013508 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.85408435 |
| 81 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.83446724 |
| 82 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.83238136 |
| 83 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.83030348 |
| 84 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.82151928 |
| 85 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.81637642 |
| 86 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80468190 |
| 87 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.78302091 |
| 88 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.75582703 |
| 89 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75436911 |
| 90 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.75055103 |
| 91 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.75003304 |
| 92 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.74729861 |
| 93 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.74234857 |
| 94 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.73683337 |
| 95 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.73623193 |
| 96 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.73312938 |
| 97 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.73070807 |
| 98 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.72189881 |
| 99 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.72189881 |
| 100 | P300_27268052_Chip-Seq_Bcells_Human | 0.71864020 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009333_abnormal_splenocyte_physiolog | 4.95668804 |
| 2 | MP0005671_abnormal_response_to | 4.67371992 |
| 3 | MP0003763_abnormal_thymus_physiology | 4.10518614 |
| 4 | MP0003436_decreased_susceptibility_to | 3.24265839 |
| 5 | MP0009785_altered_susceptibility_to | 3.01835118 |
| 6 | MP0006082_CNS_inflammation | 2.96763302 |
| 7 | MP0001800_abnormal_humoral_immune | 2.95768182 |
| 8 | MP0005000_abnormal_immune_tolerance | 2.93352014 |
| 9 | MP0009278_abnormal_bone_marrow | 2.87523734 |
| 10 | MP0002876_abnormal_thyroid_physiology | 2.80928038 |
| 11 | MP0002148_abnormal_hypersensitivity_rea | 2.76537085 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.70187958 |
| 13 | MP0001819_abnormal_immune_cell | 2.61863181 |
| 14 | MP0001835_abnormal_antigen_presentation | 2.59829160 |
| 15 | MP0005387_immune_system_phenotype | 2.59827156 |
| 16 | MP0001790_abnormal_immune_system | 2.59827156 |
| 17 | MP0002723_abnormal_immune_serum | 2.51588330 |
| 18 | MP0005025_abnormal_response_to | 2.39570541 |
| 19 | MP0003866_abnormal_defecation | 2.35135209 |
| 20 | MP0000685_abnormal_immune_system | 2.33039713 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.23064572 |
| 22 | MP0003183_abnormal_peptide_metabolism | 2.21102461 |
| 23 | MP0000703_abnormal_thymus_morphology | 2.20066755 |
| 24 | MP0002419_abnormal_innate_immunity | 2.19957311 |
| 25 | MP0003045_fibrosis | 2.14830977 |
| 26 | MP0002398_abnormal_bone_marrow | 2.08928512 |
| 27 | MP0000716_abnormal_immune_system | 2.08867787 |
| 28 | MP0010155_abnormal_intestine_physiology | 1.99160508 |
| 29 | MP0009764_decreased_sensitivity_to | 1.97293266 |
| 30 | MP0000678_abnormal_parathyroid_gland | 1.96187408 |
| 31 | MP0002405_respiratory_system_inflammati | 1.84886290 |
| 32 | MP0005360_urolithiasis | 1.72822235 |
| 33 | MP0001501_abnormal_sleep_pattern | 1.72811807 |
| 34 | MP0001968_abnormal_touch/_nociception | 1.71862335 |
| 35 | MP0002722_abnormal_immune_system | 1.71452236 |
| 36 | MP0003724_increased_susceptibility_to | 1.70632469 |
| 37 | MP0005310_abnormal_salivary_gland | 1.66991679 |
| 38 | MP0000689_abnormal_spleen_morphology | 1.63855286 |
| 39 | MP0009765_abnormal_xenobiotic_induced | 1.59859231 |
| 40 | MP0001845_abnormal_inflammatory_respons | 1.58279601 |
| 41 | MP0002429_abnormal_blood_cell | 1.56954899 |
| 42 | MP0001533_abnormal_skeleton_physiology | 1.46802598 |
| 43 | MP0000681_abnormal_thyroid_gland | 1.44773015 |
| 44 | MP0004947_skin_inflammation | 1.43918700 |
| 45 | MP0001873_stomach_inflammation | 1.43801628 |
| 46 | MP0002277_abnormal_respiratory_mucosa | 1.38146458 |
| 47 | MP0006035_abnormal_mitochondrial_morpho | 1.36947532 |
| 48 | MP0005257_abnormal_intraocular_pressure | 1.32510943 |
| 49 | MP0008872_abnormal_physiological_respon | 1.20559090 |
| 50 | MP0003191_abnormal_cellular_cholesterol | 1.20315977 |
| 51 | MP0008469_abnormal_protein_level | 1.17971187 |
| 52 | MP0005464_abnormal_platelet_physiology | 1.17890454 |
| 53 | MP0003448_altered_tumor_morphology | 1.16996986 |
| 54 | MP0002998_abnormal_bone_remodeling | 1.13137957 |
| 55 | MP0002693_abnormal_pancreas_physiology | 1.12272880 |
| 56 | MP0005503_abnormal_tendon_morphology | 1.08284705 |
| 57 | MP0001664_abnormal_digestion | 1.06725931 |
| 58 | MP0009780_abnormal_chondrocyte_physiolo | 1.03731073 |
| 59 | MP0004381_abnormal_hair_follicle | 1.01808382 |
| 60 | MP0001851_eye_inflammation | 0.99375010 |
| 61 | MP0006054_spinal_hemorrhage | 0.98943853 |
| 62 | MP0001919_abnormal_reproductive_system | 0.96926233 |
| 63 | MP0001853_heart_inflammation | 0.93775928 |
| 64 | MP0001545_abnormal_hematopoietic_system | 0.93749003 |
| 65 | MP0005397_hematopoietic_system_phenotyp | 0.93749003 |
| 66 | MP0002163_abnormal_gland_morphology | 0.92750757 |
| 67 | MP0009763_increased_sensitivity_to | 0.91910157 |
| 68 | MP0002138_abnormal_hepatobiliary_system | 0.91406164 |
| 69 | MP0003300_gastrointestinal_ulcer | 0.85052288 |
| 70 | MP0002132_abnormal_respiratory_system | 0.84027969 |
| 71 | MP0004742_abnormal_vestibular_system | 0.83420110 |
| 72 | MP0002933_joint_inflammation | 0.80798418 |
| 73 | MP0002396_abnormal_hematopoietic_system | 0.79599740 |
| 74 | MP0005390_skeleton_phenotype | 0.78627745 |
| 75 | MP0003959_abnormal_lean_body | 0.76015202 |
| 76 | MP0002166_altered_tumor_susceptibility | 0.73497553 |
| 77 | MP0002019_abnormal_tumor_incidence | 0.71931165 |
| 78 | MP0003279_aneurysm | 0.71846019 |
| 79 | MP0003638_abnormal_response/metabolism_ | 0.68916206 |
| 80 | MP0005645_abnormal_hypothalamus_physiol | 0.68888689 |
| 81 | MP0001986_abnormal_taste_sensitivity | 0.67654318 |
| 82 | MP0003646_muscle_fatigue | 0.67633577 |
| 83 | MP0003633_abnormal_nervous_system | 0.64690055 |
| 84 | MP0000858_altered_metastatic_potential | 0.63318213 |
| 85 | MP0003075_altered_response_to | 0.61250000 |
| 86 | MP0005646_abnormal_pituitary_gland | 0.61087943 |
| 87 | MP0000569_abnormal_digit_pigmentation | 0.60487124 |
| 88 | MP0008961_abnormal_basal_metabolism | 0.57863917 |
| 89 | MP0008874_decreased_physiological_sensi | 0.57139666 |
| 90 | MP0005551_abnormal_eye_electrophysiolog | 0.57052704 |
| 91 | MP0002168_other_aberrant_phenotype | 0.55657469 |
| 92 | MP0002006_tumorigenesis | 0.53612297 |
| 93 | MP0004130_abnormal_muscle_cell | 0.53211493 |
| 94 | MP0001348_abnormal_lacrimal_gland | 0.53015741 |
| 95 | MP0001765_abnormal_ion_homeostasis | 0.52550524 |
| 96 | MP0001663_abnormal_digestive_system | 0.50689697 |
| 97 | MP0009745_abnormal_behavioral_response | 0.50680598 |
| 98 | MP0008873_increased_physiological_sensi | 0.49146927 |
| 99 | MP0004858_abnormal_nervous_system | 0.48664686 |
| 100 | MP0002971_abnormal_brown_adipose | 0.48562460 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune hemolytic anemia (HP:0001890) | 7.54284583 |
| 2 | Abnormality of T cell number (HP:0011839) | 6.99780183 |
| 3 | Thyroid-stimulating hormone excess (HP:0002925) | 6.13510958 |
| 4 | T lymphocytopenia (HP:0005403) | 5.98024340 |
| 5 | Autoimmune thrombocytopenia (HP:0001973) | 5.92098951 |
| 6 | Aplastic anemia (HP:0001915) | 5.47135369 |
| 7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 5.27603375 |
| 8 | Stomach cancer (HP:0012126) | 4.99103347 |
| 9 | Increased IgM level (HP:0003496) | 4.97587937 |
| 10 | Myositis (HP:0100614) | 4.83759965 |
| 11 | Abnormality of T cells (HP:0002843) | 4.68563786 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.26302269 |
| 13 | Eosinophilia (HP:0001880) | 4.16332741 |
| 14 | Abnormality of B cell number (HP:0010975) | 4.14610911 |
| 15 | Orchitis (HP:0100796) | 4.13122727 |
| 16 | Stomatitis (HP:0010280) | 4.00789912 |
| 17 | Granulocytopenia (HP:0001913) | 3.94653643 |
| 18 | Abnormality of macrophages (HP:0004311) | 3.88659271 |
| 19 | Abnormality of eosinophils (HP:0001879) | 3.84412690 |
| 20 | Leukocytosis (HP:0001974) | 3.54550486 |
| 21 | Abnormality of T cell physiology (HP:0011840) | 3.49676374 |
| 22 | Retrobulbar optic neuritis (HP:0100654) | 3.47258309 |
| 23 | Optic neuritis (HP:0100653) | 3.47258309 |
| 24 | Agitation (HP:0000713) | 3.41372776 |
| 25 | Hypochromic anemia (HP:0001931) | 3.33467184 |
| 26 | Vasculitis (HP:0002633) | 3.13683804 |
| 27 | Chronic diarrhea (HP:0002028) | 3.12018885 |
| 28 | Pustule (HP:0200039) | 3.11914088 |
| 29 | Hypoproteinemia (HP:0003075) | 3.11367684 |
| 30 | Volvulus (HP:0002580) | 3.05154666 |
| 31 | Congenital stationary night blindness (HP:0007642) | 3.04487967 |
| 32 | IgG deficiency (HP:0004315) | 3.04418197 |
| 33 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.98312009 |
| 34 | Recurrent bacterial skin infections (HP:0005406) | 2.97465901 |
| 35 | Severe combined immunodeficiency (HP:0004430) | 2.97270408 |
| 36 | Recurrent abscess formation (HP:0002722) | 2.94768053 |
| 37 | Mediastinal lymphadenopathy (HP:0100721) | 2.82996158 |
| 38 | Recurrent viral infections (HP:0004429) | 2.80212860 |
| 39 | Intestinal atresia (HP:0011100) | 2.78299634 |
| 40 | Recurrent fungal infections (HP:0002841) | 2.67366127 |
| 41 | IgM deficiency (HP:0002850) | 2.64860353 |
| 42 | Pulmonary infiltrates (HP:0002113) | 2.63177922 |
| 43 | Abnormality of the alveolar ridges (HP:0006477) | 2.61488076 |
| 44 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.59429810 |
| 45 | Encephalitis (HP:0002383) | 2.57851290 |
| 46 | Eczematoid dermatitis (HP:0000976) | 2.51744079 |
| 47 | Broad alveolar ridges (HP:0000187) | 2.51149774 |
| 48 | Meningitis (HP:0001287) | 2.50766675 |
| 49 | Lymphopenia (HP:0001888) | 2.41667292 |
| 50 | Joint swelling (HP:0001386) | 2.40098052 |
| 51 | Combined immunodeficiency (HP:0005387) | 2.39603565 |
| 52 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.32715012 |
| 53 | Gastrointestinal infarctions (HP:0005244) | 2.32583833 |
| 54 | Keratoconjunctivitis sicca (HP:0001097) | 2.30445046 |
| 55 | Oligodontia (HP:0000677) | 2.28689209 |
| 56 | Hypergammaglobulinemia (HP:0010702) | 2.27545944 |
| 57 | 3-Methylglutaconic aciduria (HP:0003535) | 2.27215926 |
| 58 | Abnormality of the aortic arch (HP:0012303) | 2.26859590 |
| 59 | Urticaria (HP:0001025) | 2.22752997 |
| 60 | Recurrent bronchitis (HP:0002837) | 2.18918439 |
| 61 | Lymphoma (HP:0002665) | 2.18416526 |
| 62 | IgA deficiency (HP:0002720) | 2.17472241 |
| 63 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.16932979 |
| 64 | Keratoconjunctivitis (HP:0001096) | 2.16801175 |
| 65 | Large for gestational age (HP:0001520) | 2.15065134 |
| 66 | Amyloidosis (HP:0011034) | 2.13063908 |
| 67 | Recurrent cutaneous fungal infections (HP:0011370) | 2.12430999 |
| 68 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.12430999 |
| 69 | Renal cortical cysts (HP:0000803) | 2.11776226 |
| 70 | Gangrene (HP:0100758) | 2.10780779 |
| 71 | Mesangial abnormality (HP:0001966) | 2.05134641 |
| 72 | Oral leukoplakia (HP:0002745) | 2.03775814 |
| 73 | Recurrent skin infections (HP:0001581) | 2.03165284 |
| 74 | Chronic obstructive pulmonary disease (HP:0006510) | 2.03084232 |
| 75 | Obstructive lung disease (HP:0006536) | 2.03084232 |
| 76 | Thyroiditis (HP:0100646) | 2.01887720 |
| 77 | Striae distensae (HP:0001065) | 2.01847492 |
| 78 | Abnormality of the renal cortex (HP:0011035) | 1.98782817 |
| 79 | Chest pain (HP:0100749) | 1.98153255 |
| 80 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.95103765 |
| 81 | Attenuation of retinal blood vessels (HP:0007843) | 1.94042275 |
| 82 | Gaze-evoked nystagmus (HP:0000640) | 1.93781410 |
| 83 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.92556057 |
| 84 | Acute hepatic failure (HP:0006554) | 1.92328133 |
| 85 | Peritonitis (HP:0002586) | 1.92313548 |
| 86 | Focal motor seizures (HP:0011153) | 1.92141045 |
| 87 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.90724458 |
| 88 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.90724458 |
| 89 | Metabolic alkalosis (HP:0200114) | 1.87774872 |
| 90 | Large eyes (HP:0001090) | 1.86838107 |
| 91 | Anorexia (HP:0002039) | 1.86773465 |
| 92 | Episodic fever (HP:0001954) | 1.86600067 |
| 93 | Pancytopenia (HP:0001876) | 1.84502411 |
| 94 | Severe visual impairment (HP:0001141) | 1.79175430 |
| 95 | Progressive inability to walk (HP:0002505) | 1.74635080 |
| 96 | Increased cerebral lipofuscin (HP:0011813) | 1.74504543 |
| 97 | Ileus (HP:0002595) | 1.73816238 |
| 98 | Hemoptysis (HP:0002105) | 1.72058211 |
| 99 | Panhypogammaglobulinemia (HP:0003139) | 1.71955401 |
| 100 | Poor speech (HP:0002465) | 1.69239816 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 5.40911055 |
| 2 | TXK | 4.39686407 |
| 3 | PINK1 | 4.23817131 |
| 4 | MAP4K1 | 4.00469097 |
| 5 | ERN1 | 3.33038970 |
| 6 | ITK | 3.23441443 |
| 7 | PASK | 2.95523816 |
| 8 | PIK3CA | 2.95360189 |
| 9 | KDR | 2.67025804 |
| 10 | TAOK3 | 2.31324155 |
| 11 | IRAK4 | 2.19465784 |
| 12 | CAMKK1 | 2.17234966 |
| 13 | ACVR1B | 2.15045570 |
| 14 | FES | 2.13981222 |
| 15 | CAMKK2 | 2.09169157 |
| 16 | FRK | 2.01251461 |
| 17 | CSK | 1.93144903 |
| 18 | GRK6 | 1.79701966 |
| 19 | TYRO3 | 1.71940312 |
| 20 | JAK3 | 1.67282438 |
| 21 | TESK2 | 1.66284402 |
| 22 | RIPK4 | 1.66108762 |
| 23 | TNK2 | 1.56112007 |
| 24 | BTK | 1.51894052 |
| 25 | BLK | 1.50057164 |
| 26 | ZAP70 | 1.46288565 |
| 27 | LCK | 1.45655263 |
| 28 | SYK | 1.41334672 |
| 29 | MAP3K3 | 1.39916637 |
| 30 | TAOK1 | 1.39816173 |
| 31 | MAP2K3 | 1.36234096 |
| 32 | TAOK2 | 1.34540473 |
| 33 | MAP3K11 | 1.33431508 |
| 34 | ADRBK1 | 1.33272707 |
| 35 | TEC | 1.27109148 |
| 36 | PRKCQ | 1.23410173 |
| 37 | HCK | 1.18737172 |
| 38 | IKBKE | 1.17400749 |
| 39 | LYN | 1.14884352 |
| 40 | MAPK11 | 0.96764023 |
| 41 | STK38 | 0.87012491 |
| 42 | IRAK1 | 0.84093649 |
| 43 | CLK1 | 0.82359065 |
| 44 | IKBKB | 0.81157969 |
| 45 | TYK2 | 0.77387721 |
| 46 | MARK3 | 0.70110928 |
| 47 | GRK1 | 0.66566987 |
| 48 | TBK1 | 0.65807770 |
| 49 | PRKD2 | 0.64935006 |
| 50 | FYN | 0.64816430 |
| 51 | CSF1R | 0.62074434 |
| 52 | PDK1 | 0.58266849 |
| 53 | STK10 | 0.56800726 |
| 54 | GRK7 | 0.53897066 |
| 55 | RIPK1 | 0.53652547 |
| 56 | TGFBR1 | 0.53558434 |
| 57 | CAMK1 | 0.52867634 |
| 58 | PRKCG | 0.52360012 |
| 59 | CAMK4 | 0.50936972 |
| 60 | RET | 0.50897717 |
| 61 | JAK2 | 0.50720301 |
| 62 | NLK | 0.49787580 |
| 63 | PIK3CG | 0.49663205 |
| 64 | NEK6 | 0.49601062 |
| 65 | MAPK12 | 0.49536160 |
| 66 | IRAK3 | 0.46807329 |
| 67 | KIT | 0.46335293 |
| 68 | NUAK1 | 0.45801074 |
| 69 | BCKDK | 0.42837580 |
| 70 | PRKCH | 0.41298705 |
| 71 | EIF2AK3 | 0.40494851 |
| 72 | JAK1 | 0.39753143 |
| 73 | IGF1R | 0.39650555 |
| 74 | MAP3K10 | 0.39163215 |
| 75 | PRKCE | 0.37587485 |
| 76 | MAP3K1 | 0.37365037 |
| 77 | CAMK2A | 0.37339726 |
| 78 | DAPK2 | 0.36754736 |
| 79 | MAP3K14 | 0.35041492 |
| 80 | PRKCD | 0.30471690 |
| 81 | MAPKAPK3 | 0.30304234 |
| 82 | PIM1 | 0.30221028 |
| 83 | TRPM7 | 0.29370142 |
| 84 | PRPF4B | 0.28914044 |
| 85 | PRKCA | 0.28513555 |
| 86 | TGFBR2 | 0.27365830 |
| 87 | MAPK3 | 0.26975267 |
| 88 | NTRK2 | 0.25208871 |
| 89 | PRKCB | 0.23396255 |
| 90 | MAP3K7 | 0.22821600 |
| 91 | BMPR1B | 0.21707275 |
| 92 | PDPK1 | 0.20097738 |
| 93 | FGFR1 | 0.18155999 |
| 94 | FGR | 0.18089470 |
| 95 | MAPKAPK2 | 0.17739480 |
| 96 | EPHB1 | 0.17674658 |
| 97 | ABL1 | 0.16576673 |
| 98 | CDK19 | 0.15725103 |
| 99 | MAP3K5 | 0.15194526 |
| 100 | MAP2K7 | 0.14129751 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.87722565 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.74647273 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.79024279 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.64089361 |
| 5 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.62387489 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.48571191 |
| 7 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.97759136 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.75168674 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.60009146 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.51188357 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.15561385 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.05118658 |
| 13 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.02166795 |
| 14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.94056402 |
| 15 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.90411607 |
| 16 | Measles_Homo sapiens_hsa05162 | 1.84160963 |
| 17 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.76167869 |
| 18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.71917320 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.65171335 |
| 20 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.64210469 |
| 21 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.57530183 |
| 22 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.56027489 |
| 23 | Viral myocarditis_Homo sapiens_hsa05416 | 1.46391364 |
| 24 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.36320613 |
| 25 | Leishmaniasis_Homo sapiens_hsa05140 | 1.31317474 |
| 26 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.28874618 |
| 27 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.27420423 |
| 28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.25432102 |
| 29 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.20045915 |
| 30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.12262872 |
| 31 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.12138592 |
| 32 | Apoptosis_Homo sapiens_hsa04210 | 1.09711410 |
| 33 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.09086960 |
| 34 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.04248518 |
| 35 | Salmonella infection_Homo sapiens_hsa05132 | 1.03589529 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.02222145 |
| 37 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.98255585 |
| 38 | Asthma_Homo sapiens_hsa05310 | 0.97816471 |
| 39 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.95836134 |
| 40 | Legionellosis_Homo sapiens_hsa05134 | 0.94073522 |
| 41 | Tuberculosis_Homo sapiens_hsa05152 | 0.91020333 |
| 42 | Malaria_Homo sapiens_hsa05144 | 0.88699183 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.86310460 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.85674207 |
| 45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.79135227 |
| 46 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.78002816 |
| 47 | Influenza A_Homo sapiens_hsa05164 | 0.76194170 |
| 48 | ABC transporters_Homo sapiens_hsa02010 | 0.75627415 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71050919 |
| 50 | Proteasome_Homo sapiens_hsa03050 | 0.67683006 |
| 51 | Phototransduction_Homo sapiens_hsa04744 | 0.64639962 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.64341292 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.63114689 |
| 54 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.62099571 |
| 55 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.58305401 |
| 56 | Morphine addiction_Homo sapiens_hsa05032 | 0.55282762 |
| 57 | HTLV-I infection_Homo sapiens_hsa05166 | 0.47997762 |
| 58 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.47730338 |
| 59 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46036227 |
| 60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.45122980 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44417551 |
| 62 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.42424427 |
| 63 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.41958808 |
| 64 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.41549684 |
| 65 | Pertussis_Homo sapiens_hsa05133 | 0.41211272 |
| 66 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.40526145 |
| 67 | Hepatitis B_Homo sapiens_hsa05161 | 0.40120887 |
| 68 | Shigellosis_Homo sapiens_hsa05131 | 0.39173524 |
| 69 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.36936999 |
| 70 | Platelet activation_Homo sapiens_hsa04611 | 0.36450191 |
| 71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.34356697 |
| 72 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.34089912 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30663527 |
| 74 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.30161451 |
| 75 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.30117862 |
| 76 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.29358925 |
| 77 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.27282252 |
| 78 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27117783 |
| 79 | Endocytosis_Homo sapiens_hsa04144 | 0.26042333 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.25342790 |
| 81 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.24156516 |
| 82 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.23939563 |
| 83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.20430342 |
| 84 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.18953792 |
| 85 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.17518720 |
| 86 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.16457255 |
| 87 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.16044701 |
| 88 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.15903734 |
| 89 | Lysosome_Homo sapiens_hsa04142 | 0.15780023 |
| 90 | Salivary secretion_Homo sapiens_hsa04970 | 0.14658029 |
| 91 | Ribosome_Homo sapiens_hsa03010 | 0.13655256 |
| 92 | Phagosome_Homo sapiens_hsa04145 | 0.12782013 |
| 93 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.11168858 |
| 94 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.11068785 |
| 95 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.11002300 |
| 96 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.10597126 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.10525279 |
| 98 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10347613 |
| 99 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.10307727 |
| 100 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.09781920 |

