

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.90736904 |
| 2 | negative regulation of cell killing (GO:0031342) | 6.87876425 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.87876425 |
| 4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.82932728 |
| 5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.72396323 |
| 6 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.30712019 |
| 7 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.17885799 |
| 8 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.12938580 |
| 9 | response to interleukin-15 (GO:0070672) | 6.04878312 |
| 10 | negative T cell selection (GO:0043383) | 5.93599136 |
| 11 | negative thymic T cell selection (GO:0045060) | 5.77511629 |
| 12 | cellular response to interleukin-15 (GO:0071350) | 5.71364391 |
| 13 | regulation of regulatory T cell differentiation (GO:0045589) | 5.55256926 |
| 14 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.29614245 |
| 15 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.26717176 |
| 16 | tolerance induction (GO:0002507) | 5.23580276 |
| 17 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.00795233 |
| 18 | regulation of gamma-delta T cell activation (GO:0046643) | 5.00031641 |
| 19 | leukocyte aggregation (GO:0070486) | 4.68181649 |
| 20 | regulation of T cell tolerance induction (GO:0002664) | 4.52699321 |
| 21 | activated T cell proliferation (GO:0050798) | 4.41115189 |
| 22 | thymic T cell selection (GO:0045061) | 4.37522190 |
| 23 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.26267813 |
| 24 | negative regulation of T cell mediated immunity (GO:0002710) | 4.24878525 |
| 25 | T cell selection (GO:0045058) | 4.18384798 |
| 26 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.16119680 |
| 27 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.15269081 |
| 28 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.14979321 |
| 29 | T cell migration (GO:0072678) | 4.12429790 |
| 30 | positive T cell selection (GO:0043368) | 4.01800244 |
| 31 | positive thymic T cell selection (GO:0045059) | 3.99221710 |
| 32 | regulation of tolerance induction (GO:0002643) | 3.84997052 |
| 33 | positive regulation of granulocyte differentiation (GO:0030854) | 3.83091974 |
| 34 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.81103345 |
| 35 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.77057333 |
| 36 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.77057333 |
| 37 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.76519662 |
| 38 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.74590830 |
| 39 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.73794386 |
| 40 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.73794386 |
| 41 | modulation by symbiont of host immune response (GO:0052553) | 3.73794386 |
| 42 | positive regulation by symbiont of host defense response (GO:0052509) | 3.73794386 |
| 43 | modulation by symbiont of host defense response (GO:0052031) | 3.73794386 |
| 44 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.73794386 |
| 45 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.72980191 |
| 46 | positive regulation of tolerance induction (GO:0002645) | 3.69404978 |
| 47 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.60766796 |
| 48 | detection of bacterium (GO:0016045) | 3.59954290 |
| 49 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.57878727 |
| 50 | T cell receptor signaling pathway (GO:0050852) | 3.54385670 |
| 51 | detection of other organism (GO:0098543) | 3.53843333 |
| 52 | neutrophil activation involved in immune response (GO:0002283) | 3.51959089 |
| 53 | interferon-gamma production (GO:0032609) | 3.51217668 |
| 54 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.48789667 |
| 55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.46928932 |
| 56 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.46884937 |
| 57 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.46884937 |
| 58 | regulation of B cell differentiation (GO:0045577) | 3.45559058 |
| 59 | T cell homeostasis (GO:0043029) | 3.45466613 |
| 60 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.41603033 |
| 61 | negative regulation of interleukin-12 production (GO:0032695) | 3.41394434 |
| 62 | type I interferon signaling pathway (GO:0060337) | 3.39607453 |
| 63 | cellular response to type I interferon (GO:0071357) | 3.39607453 |
| 64 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.37743412 |
| 65 | response to type I interferon (GO:0034340) | 3.37231671 |
| 66 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.36173328 |
| 67 | B cell receptor signaling pathway (GO:0050853) | 3.35748230 |
| 68 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.32616999 |
| 69 | positive regulation of B cell differentiation (GO:0045579) | 3.32241429 |
| 70 | positive regulation of humoral immune response (GO:0002922) | 3.31830846 |
| 71 | mast cell activation (GO:0045576) | 3.26601474 |
| 72 | positive regulation of interleukin-4 production (GO:0032753) | 3.25154234 |
| 73 | positive regulation of isotype switching (GO:0045830) | 3.22363163 |
| 74 | positive regulation of interleukin-2 production (GO:0032743) | 3.21564098 |
| 75 | cellular extravasation (GO:0045123) | 3.17941648 |
| 76 | alpha-beta T cell differentiation (GO:0046632) | 3.15983790 |
| 77 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.12209023 |
| 78 | neutrophil activation (GO:0042119) | 3.11145754 |
| 79 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.08439705 |
| 80 | positive regulation of cell killing (GO:0031343) | 3.05867627 |
| 81 | regulation of cell killing (GO:0031341) | 3.03531235 |
| 82 | leukocyte degranulation (GO:0043299) | 3.03494255 |
| 83 | positive regulation of DNA recombination (GO:0045911) | 3.02320707 |
| 84 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.01799034 |
| 85 | positive regulation of T cell mediated immunity (GO:0002711) | 3.01406991 |
| 86 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.00564328 |
| 87 | alpha-beta T cell activation (GO:0046631) | 3.00414347 |
| 88 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.99815036 |
| 89 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 2.98499412 |
| 90 | regulation of isotype switching (GO:0045191) | 2.96939186 |
| 91 | myeloid cell activation involved in immune response (GO:0002275) | 2.96141102 |
| 92 | regulation of alpha-beta T cell activation (GO:0046634) | 2.96084617 |
| 93 | regulation of T cell mediated immunity (GO:0002709) | 2.93676354 |
| 94 | myeloid dendritic cell activation (GO:0001773) | 2.93176991 |
| 95 | negative regulation of innate immune response (GO:0045824) | 2.92787481 |
| 96 | negative regulation of adaptive immune response (GO:0002820) | 2.90517738 |
| 97 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.89464827 |
| 98 | dendritic cell chemotaxis (GO:0002407) | 2.89001377 |
| 99 | cytokine biosynthetic process (GO:0042089) | 2.87902107 |
| 100 | lymphocyte homeostasis (GO:0002260) | 2.87116104 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.48380197 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.81197712 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.06747265 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.75028727 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.64078897 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.63544344 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.49309745 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.44847416 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.40215258 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.25010352 |
| 11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.24552434 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.14458507 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.01545877 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.79884639 |
| 15 | MAF_26560356_Chip-Seq_TH1_Human | 2.72248165 |
| 16 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.64068402 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.58227270 |
| 18 | MYB_26560356_Chip-Seq_TH1_Human | 2.56722827 |
| 19 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.53778223 |
| 20 | UTX_26944678_Chip-Seq_JUKART_Human | 2.43578415 |
| 21 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.37073063 |
| 22 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.36570260 |
| 23 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.34382134 |
| 24 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.27094492 |
| 25 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.24277001 |
| 26 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.17218407 |
| 27 | MAF_26560356_Chip-Seq_TH2_Human | 2.13386224 |
| 28 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.10686094 |
| 29 | MYC_22102868_ChIP-Seq_BL_Human | 2.09722171 |
| 30 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.98988597 |
| 31 | SPI1_23127762_ChIP-Seq_K562_Human | 1.95940595 |
| 32 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.90104522 |
| 33 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.90059741 |
| 34 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.86867699 |
| 35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81900515 |
| 36 | GATA3_26560356_Chip-Seq_TH2_Human | 1.80558133 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.80305396 |
| 38 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.73464786 |
| 39 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69344054 |
| 40 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.63520095 |
| 41 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.62970920 |
| 42 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.58841107 |
| 43 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.57260219 |
| 44 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.54729876 |
| 45 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.47080882 |
| 46 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.44004317 |
| 47 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.41712264 |
| 48 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.39593051 |
| 49 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36176479 |
| 50 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33775316 |
| 51 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.29459800 |
| 52 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26654993 |
| 53 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.24682333 |
| 54 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.21610577 |
| 55 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.19444422 |
| 56 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.19315655 |
| 57 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.19303185 |
| 58 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.18332007 |
| 59 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.18087602 |
| 60 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.17758250 |
| 61 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.17054234 |
| 62 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.14185524 |
| 63 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.12930556 |
| 64 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11424368 |
| 65 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08636313 |
| 66 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.06521485 |
| 67 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.06437687 |
| 68 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06320507 |
| 69 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.05356736 |
| 70 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.04871007 |
| 71 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.03919404 |
| 72 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.02387195 |
| 73 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.01594834 |
| 74 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.00775181 |
| 75 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00166537 |
| 76 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.99764584 |
| 77 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.99447294 |
| 78 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.98342441 |
| 79 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95935778 |
| 80 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.94750834 |
| 81 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.92888885 |
| 82 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92374315 |
| 83 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.90086738 |
| 84 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89073606 |
| 85 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.88158921 |
| 86 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.87330391 |
| 87 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.87090074 |
| 88 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86120619 |
| 89 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.84375246 |
| 90 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.84281090 |
| 91 | GATA3_26560356_Chip-Seq_TH1_Human | 0.83816411 |
| 92 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.82389838 |
| 93 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.81728381 |
| 94 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.81656979 |
| 95 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.81199004 |
| 96 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.79907117 |
| 97 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.79846597 |
| 98 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78812974 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.76390403 |
| 100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75764728 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.42500670 |
| 2 | MP0005671_abnormal_response_to | 4.18321958 |
| 3 | MP0003436_decreased_susceptibility_to | 3.99065955 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.93474211 |
| 5 | MP0001800_abnormal_humoral_immune | 3.35293971 |
| 6 | MP0003724_increased_susceptibility_to | 3.31638253 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.15780311 |
| 8 | MP0001790_abnormal_immune_system | 2.97004845 |
| 9 | MP0005387_immune_system_phenotype | 2.97004845 |
| 10 | MP0002723_abnormal_immune_serum | 2.86257360 |
| 11 | MP0001873_stomach_inflammation | 2.85006317 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.80107220 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 2.76716195 |
| 14 | MP0001819_abnormal_immune_cell | 2.75545183 |
| 15 | MP0002452_abnormal_antigen_presenting | 2.62963769 |
| 16 | MP0009333_abnormal_splenocyte_physiolog | 2.62581397 |
| 17 | MP0005025_abnormal_response_to | 2.61082811 |
| 18 | MP0000685_abnormal_immune_system | 2.59150291 |
| 19 | MP0002419_abnormal_innate_immunity | 2.54981612 |
| 20 | MP0009785_altered_susceptibility_to | 2.51813845 |
| 21 | MP0003866_abnormal_defecation | 2.39739887 |
| 22 | MP0000703_abnormal_thymus_morphology | 2.38162361 |
| 23 | MP0006082_CNS_inflammation | 2.37934858 |
| 24 | MP0002398_abnormal_bone_marrow | 2.37742724 |
| 25 | MP0002405_respiratory_system_inflammati | 2.36481366 |
| 26 | MP0003300_gastrointestinal_ulcer | 2.25208493 |
| 27 | MP0000465_gastrointestinal_hemorrhage | 2.24573770 |
| 28 | MP0000716_abnormal_immune_system | 2.22044585 |
| 29 | MP0003303_peritoneal_inflammation | 2.21083479 |
| 30 | MP0010155_abnormal_intestine_physiology | 2.10733233 |
| 31 | MP0002722_abnormal_immune_system | 1.97252224 |
| 32 | MP0005310_abnormal_salivary_gland | 1.95884348 |
| 33 | MP0005464_abnormal_platelet_physiology | 1.95006667 |
| 34 | MP0000689_abnormal_spleen_morphology | 1.94261047 |
| 35 | MP0002396_abnormal_hematopoietic_system | 1.93145740 |
| 36 | MP0002277_abnormal_respiratory_mucosa | 1.92493919 |
| 37 | MP0004947_skin_inflammation | 1.80109330 |
| 38 | MP0004381_abnormal_hair_follicle | 1.79146579 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.78705891 |
| 40 | MP0002429_abnormal_blood_cell | 1.75822425 |
| 41 | MP0001533_abnormal_skeleton_physiology | 1.73907233 |
| 42 | MP0008260_abnormal_autophagy | 1.69534074 |
| 43 | MP0003183_abnormal_peptide_metabolism | 1.69265186 |
| 44 | MP0002166_altered_tumor_susceptibility | 1.46082109 |
| 45 | MP0008469_abnormal_protein_level | 1.45423783 |
| 46 | MP0001851_eye_inflammation | 1.31042057 |
| 47 | MP0002933_joint_inflammation | 1.30340510 |
| 48 | MP0003806_abnormal_nucleotide_metabolis | 1.26953927 |
| 49 | MP0009764_decreased_sensitivity_to | 1.25666333 |
| 50 | MP0005075_abnormal_melanosome_morpholog | 1.23410738 |
| 51 | MP0001348_abnormal_lacrimal_gland | 1.21018689 |
| 52 | MP0002132_abnormal_respiratory_system | 1.16327121 |
| 53 | MP0002006_tumorigenesis | 1.15481637 |
| 54 | MP0002138_abnormal_hepatobiliary_system | 1.10018661 |
| 55 | MP0003191_abnormal_cellular_cholesterol | 1.03713997 |
| 56 | MP0002163_abnormal_gland_morphology | 0.98712026 |
| 57 | MP0001663_abnormal_digestive_system | 0.93230086 |
| 58 | MP0001853_heart_inflammation | 0.90209859 |
| 59 | MP0000490_abnormal_crypts_of | 0.83526275 |
| 60 | MP0002998_abnormal_bone_remodeling | 0.81398889 |
| 61 | MP0001986_abnormal_taste_sensitivity | 0.80193273 |
| 62 | MP0009278_abnormal_bone_marrow | 0.79470170 |
| 63 | MP0002019_abnormal_tumor_incidence | 0.79438978 |
| 64 | MP0003828_pulmonary_edema | 0.78398882 |
| 65 | MP0000858_altered_metastatic_potential | 0.78262949 |
| 66 | MP0005166_decreased_susceptibility_to | 0.76214600 |
| 67 | MP0003075_altered_response_to | 0.76141296 |
| 68 | MP0003448_altered_tumor_morphology | 0.75644495 |
| 69 | MP0004883_abnormal_blood_vessel | 0.75571442 |
| 70 | MP0003045_fibrosis | 0.75439501 |
| 71 | MP0002693_abnormal_pancreas_physiology | 0.71308845 |
| 72 | MP0009763_increased_sensitivity_to | 0.71213034 |
| 73 | MP0003221_abnormal_cardiomyocyte_apopto | 0.67709753 |
| 74 | MP0003172_abnormal_lysosome_physiology | 0.63533266 |
| 75 | MP0004808_abnormal_hematopoietic_stem | 0.63036753 |
| 76 | MP0005390_skeleton_phenotype | 0.59618585 |
| 77 | MP0002928_abnormal_bile_duct | 0.59130043 |
| 78 | MP0005083_abnormal_biliary_tract | 0.59106713 |
| 79 | MP0004510_myositis | 0.57070265 |
| 80 | MP0005164_abnormal_response_to | 0.56514180 |
| 81 | MP0006035_abnormal_mitochondrial_morpho | 0.56378539 |
| 82 | MP0003690_abnormal_glial_cell | 0.55963899 |
| 83 | MP0003795_abnormal_bone_structure | 0.53432170 |
| 84 | MP0005319_abnormal_enzyme/_coenzyme | 0.52811913 |
| 85 | MP0008873_increased_physiological_sensi | 0.52580223 |
| 86 | MP0000249_abnormal_blood_vessel | 0.51834363 |
| 87 | MP0009765_abnormal_xenobiotic_induced | 0.51516147 |
| 88 | MP0004130_abnormal_muscle_cell | 0.51305404 |
| 89 | MP0000604_amyloidosis | 0.49894550 |
| 90 | MP0008874_decreased_physiological_sensi | 0.49169192 |
| 91 | MP0003252_abnormal_bile_duct | 0.48745727 |
| 92 | MP0000920_abnormal_myelination | 0.47701535 |
| 93 | MP0003633_abnormal_nervous_system | 0.47647714 |
| 94 | MP0008872_abnormal_physiological_respon | 0.47271090 |
| 95 | MP0005381_digestive/alimentary_phenotyp | 0.46394615 |
| 96 | MP0008057_abnormal_DNA_replication | 0.44017153 |
| 97 | MP0005376_homeostasis/metabolism_phenot | 0.43446168 |
| 98 | MP0002332_abnormal_exercise_endurance | 0.42057011 |
| 99 | MP0001545_abnormal_hematopoietic_system | 0.41110521 |
| 100 | MP0005397_hematopoietic_system_phenotyp | 0.41110521 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.93069306 |
| 2 | T lymphocytopenia (HP:0005403) | 5.77313575 |
| 3 | Stomatitis (HP:0010280) | 5.65939175 |
| 4 | Abnormality of T cell number (HP:0011839) | 5.34707747 |
| 5 | Eczematoid dermatitis (HP:0000976) | 5.24904517 |
| 6 | Myositis (HP:0100614) | 4.99321230 |
| 7 | Encephalitis (HP:0002383) | 4.57931655 |
| 8 | Autoimmune hemolytic anemia (HP:0001890) | 4.52991145 |
| 9 | Orchitis (HP:0100796) | 4.39029036 |
| 10 | Optic neuritis (HP:0100653) | 4.35263983 |
| 11 | Retrobulbar optic neuritis (HP:0100654) | 4.35263983 |
| 12 | Abnormality of T cells (HP:0002843) | 4.31444788 |
| 13 | Recurrent fungal infections (HP:0002841) | 4.26305145 |
| 14 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.20747858 |
| 15 | Recurrent abscess formation (HP:0002722) | 4.17420132 |
| 16 | Recurrent bacterial skin infections (HP:0005406) | 4.13925725 |
| 17 | Recurrent cutaneous fungal infections (HP:0011370) | 4.01131373 |
| 18 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.01131373 |
| 19 | Severe combined immunodeficiency (HP:0004430) | 3.91582646 |
| 20 | Gastrointestinal infarctions (HP:0005244) | 3.77431220 |
| 21 | Granulocytopenia (HP:0001913) | 3.76427202 |
| 22 | Abnormality of macrophages (HP:0004311) | 3.76421936 |
| 23 | Pustule (HP:0200039) | 3.67125249 |
| 24 | Panhypogammaglobulinemia (HP:0003139) | 3.59318397 |
| 25 | Chronic diarrhea (HP:0002028) | 3.56641353 |
| 26 | IgM deficiency (HP:0002850) | 3.56490601 |
| 27 | Meningitis (HP:0001287) | 3.55212864 |
| 28 | Abnormality of eosinophils (HP:0001879) | 3.48978115 |
| 29 | Eosinophilia (HP:0001880) | 3.46645802 |
| 30 | Obstructive lung disease (HP:0006536) | 3.43755939 |
| 31 | Chronic obstructive pulmonary disease (HP:0006510) | 3.43755939 |
| 32 | IgG deficiency (HP:0004315) | 3.42384670 |
| 33 | Leukocytosis (HP:0001974) | 3.41409723 |
| 34 | Increased IgM level (HP:0003496) | 3.39811969 |
| 35 | Keratoconjunctivitis sicca (HP:0001097) | 3.35563188 |
| 36 | Recurrent bronchitis (HP:0002837) | 3.32319080 |
| 37 | Recurrent skin infections (HP:0001581) | 3.31919188 |
| 38 | Vasculitis (HP:0002633) | 3.31278466 |
| 39 | Mediastinal lymphadenopathy (HP:0100721) | 3.26722506 |
| 40 | Spontaneous hematomas (HP:0007420) | 3.17885563 |
| 41 | Abnormality of T cell physiology (HP:0011840) | 3.13209181 |
| 42 | Keratoconjunctivitis (HP:0001096) | 3.12198166 |
| 43 | Recurrent viral infections (HP:0004429) | 3.09094609 |
| 44 | Pulmonary infiltrates (HP:0002113) | 3.07103317 |
| 45 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.06491535 |
| 46 | Combined immunodeficiency (HP:0005387) | 3.04274366 |
| 47 | Lymphopenia (HP:0001888) | 2.98186501 |
| 48 | Chest pain (HP:0100749) | 2.94434483 |
| 49 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.83398148 |
| 50 | Hemoptysis (HP:0002105) | 2.81631969 |
| 51 | Increased IgE level (HP:0003212) | 2.80629198 |
| 52 | Hypochromic microcytic anemia (HP:0004840) | 2.80053248 |
| 53 | Urticaria (HP:0001025) | 2.80010176 |
| 54 | Inflammation of the large intestine (HP:0002037) | 2.75888477 |
| 55 | Joint swelling (HP:0001386) | 2.74542319 |
| 56 | Abnormality of lateral ventricle (HP:0030047) | 2.66821672 |
| 57 | Gastrointestinal inflammation (HP:0004386) | 2.65942390 |
| 58 | Agammaglobulinemia (HP:0004432) | 2.63373540 |
| 59 | Hypochromic anemia (HP:0001931) | 2.53714347 |
| 60 | Pulmonary embolism (HP:0002204) | 2.49521615 |
| 61 | Microcytic anemia (HP:0001935) | 2.48749149 |
| 62 | Lymphoma (HP:0002665) | 2.39217205 |
| 63 | Anorexia (HP:0002039) | 2.37072925 |
| 64 | Amaurosis fugax (HP:0100576) | 2.33119473 |
| 65 | Hypoplasia of the thymus (HP:0000778) | 2.32563606 |
| 66 | Arterial thrombosis (HP:0004420) | 2.30600532 |
| 67 | Hypergammaglobulinemia (HP:0010702) | 2.30530442 |
| 68 | Prolonged bleeding time (HP:0003010) | 2.28621305 |
| 69 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.27889615 |
| 70 | Epistaxis (HP:0000421) | 2.26292729 |
| 71 | Abnormality of B cell number (HP:0010975) | 2.22238365 |
| 72 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.17693919 |
| 73 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.17449125 |
| 74 | Abnormality of the pleura (HP:0002103) | 2.17224470 |
| 75 | Stomach cancer (HP:0012126) | 2.16913735 |
| 76 | Vertigo (HP:0002321) | 2.16669910 |
| 77 | Gangrene (HP:0100758) | 2.15822804 |
| 78 | B lymphocytopenia (HP:0010976) | 2.14779352 |
| 79 | Gingivitis (HP:0000230) | 2.13553154 |
| 80 | Fatigue (HP:0012378) | 2.13146357 |
| 81 | Sepsis (HP:0100806) | 2.11850740 |
| 82 | Skin rash (HP:0000988) | 2.10199595 |
| 83 | Colitis (HP:0002583) | 2.07889667 |
| 84 | Papilledema (HP:0001085) | 2.07763375 |
| 85 | Hepatosplenomegaly (HP:0001433) | 2.06807722 |
| 86 | Petechiae (HP:0000967) | 2.06637965 |
| 87 | Acute hepatic failure (HP:0006554) | 2.05909245 |
| 88 | Verrucae (HP:0200043) | 2.04084372 |
| 89 | Papilloma (HP:0012740) | 2.04084372 |
| 90 | Alveolar cell carcinoma (HP:0006519) | 2.03011599 |
| 91 | Basal cell carcinoma (HP:0002671) | 2.00571659 |
| 92 | Thyroiditis (HP:0100646) | 2.00172458 |
| 93 | Gingival bleeding (HP:0000225) | 1.98647071 |
| 94 | Glomerulopathy (HP:0100820) | 1.97571100 |
| 95 | Episodic fever (HP:0001954) | 1.94965372 |
| 96 | Cellulitis (HP:0100658) | 1.91992902 |
| 97 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.91621158 |
| 98 | Chronic otitis media (HP:0000389) | 1.90916726 |
| 99 | Recurrent sinusitis (HP:0011108) | 1.89844573 |
| 100 | Skin ulcer (HP:0200042) | 1.89222590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.34802686 |
| 2 | MAP4K1 | 4.63649243 |
| 3 | RIPK4 | 2.86868690 |
| 4 | PRPF4B | 2.83678788 |
| 5 | TNK2 | 2.81941850 |
| 6 | TYK2 | 2.71385817 |
| 7 | FES | 2.68632050 |
| 8 | MAP2K3 | 2.68186387 |
| 9 | ZAP70 | 2.48371599 |
| 10 | CSK | 2.33618071 |
| 11 | MAP3K13 | 2.33151991 |
| 12 | ITK | 2.24179033 |
| 13 | GRK6 | 2.14112262 |
| 14 | BTK | 1.99333987 |
| 15 | TAOK3 | 1.88222056 |
| 16 | ERN1 | 1.77324775 |
| 17 | JAK3 | 1.73287036 |
| 18 | LCK | 1.71460514 |
| 19 | BLK | 1.66635214 |
| 20 | IKBKE | 1.65099073 |
| 21 | HCK | 1.64754668 |
| 22 | PASK | 1.63145184 |
| 23 | MAP3K3 | 1.58934543 |
| 24 | IRAK4 | 1.57844679 |
| 25 | MAP3K11 | 1.57701406 |
| 26 | SYK | 1.57142597 |
| 27 | SIK3 | 1.52569810 |
| 28 | EPHB1 | 1.51880580 |
| 29 | JAK1 | 1.48403976 |
| 30 | MAP3K14 | 1.46854617 |
| 31 | TEC | 1.34753029 |
| 32 | TAOK2 | 1.30422306 |
| 33 | STK10 | 1.29732407 |
| 34 | MAP3K12 | 1.29153694 |
| 35 | MAP3K6 | 1.28569269 |
| 36 | CLK1 | 1.22186655 |
| 37 | LYN | 1.21368466 |
| 38 | FGFR4 | 1.14567024 |
| 39 | JAK2 | 1.09501563 |
| 40 | PRKCQ | 1.07525985 |
| 41 | STK16 | 1.04688287 |
| 42 | NLK | 1.03633209 |
| 43 | CAMKK2 | 1.02752126 |
| 44 | TBK1 | 1.02537595 |
| 45 | CDK19 | 1.01331009 |
| 46 | KIT | 1.01207203 |
| 47 | CAMKK1 | 1.00345902 |
| 48 | MAP2K6 | 0.95497472 |
| 49 | SMG1 | 0.92779111 |
| 50 | PTK6 | 0.88311315 |
| 51 | NEK9 | 0.87519212 |
| 52 | MAP3K7 | 0.86979928 |
| 53 | SRPK1 | 0.84047106 |
| 54 | MARK3 | 0.83828394 |
| 55 | FGFR3 | 0.83736101 |
| 56 | TAOK1 | 0.82222331 |
| 57 | MAP3K1 | 0.81694294 |
| 58 | IKBKB | 0.81154205 |
| 59 | MAP3K5 | 0.80605834 |
| 60 | INSRR | 0.76093319 |
| 61 | TESK2 | 0.74766012 |
| 62 | CSF1R | 0.74589864 |
| 63 | NUAK1 | 0.74435936 |
| 64 | MAPK11 | 0.73497166 |
| 65 | SIK2 | 0.67913262 |
| 66 | PDK1 | 0.65867925 |
| 67 | FYN | 0.64894308 |
| 68 | MAP2K4 | 0.63685161 |
| 69 | EIF2AK1 | 0.61632002 |
| 70 | PIM1 | 0.55631072 |
| 71 | FGR | 0.53254808 |
| 72 | HIPK2 | 0.51616486 |
| 73 | MAPK12 | 0.50907375 |
| 74 | CDK4 | 0.50675804 |
| 75 | PIK3CG | 0.50520647 |
| 76 | KSR2 | 0.50157982 |
| 77 | GRK7 | 0.50097895 |
| 78 | YES1 | 0.48502858 |
| 79 | LRRK2 | 0.47816258 |
| 80 | EIF2AK3 | 0.45569899 |
| 81 | MARK2 | 0.45141313 |
| 82 | TYRO3 | 0.45131712 |
| 83 | STK38 | 0.43280547 |
| 84 | PTK2B | 0.42104876 |
| 85 | RAF1 | 0.41029501 |
| 86 | TGFBR2 | 0.40063500 |
| 87 | RET | 0.40000800 |
| 88 | CCNB1 | 0.39900623 |
| 89 | MAPK7 | 0.34586268 |
| 90 | MOS | 0.33223005 |
| 91 | MAPKAPK2 | 0.28837025 |
| 92 | EPHA3 | 0.28403197 |
| 93 | IRAK1 | 0.28351672 |
| 94 | TLK1 | 0.25842185 |
| 95 | NEK6 | 0.25526237 |
| 96 | MAP3K8 | 0.25069028 |
| 97 | INSR | 0.22744635 |
| 98 | PRKCD | 0.21052156 |
| 99 | KDR | 0.19420774 |
| 100 | PDGFRB | 0.19203444 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.11938626 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.27405756 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.14351089 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.12057340 |
| 5 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.10698922 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.08666479 |
| 7 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.49094267 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.48981196 |
| 9 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.44465814 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.25507995 |
| 11 | Leishmaniasis_Homo sapiens_hsa05140 | 2.15357170 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11299697 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.96471462 |
| 14 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.94107884 |
| 15 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.88855718 |
| 16 | Viral myocarditis_Homo sapiens_hsa05416 | 1.84993792 |
| 17 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.84615201 |
| 18 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.83208367 |
| 19 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.70574283 |
| 20 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.69160558 |
| 21 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.66990097 |
| 22 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.66482308 |
| 23 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.65946593 |
| 24 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.60385030 |
| 25 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.56881489 |
| 26 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.51718973 |
| 27 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.50471368 |
| 28 | Hepatitis B_Homo sapiens_hsa05161 | 1.40365980 |
| 29 | Tuberculosis_Homo sapiens_hsa05152 | 1.38651146 |
| 30 | Influenza A_Homo sapiens_hsa05164 | 1.29521842 |
| 31 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.27942733 |
| 32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.24641480 |
| 33 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.23587357 |
| 34 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.23028393 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.21663939 |
| 36 | Malaria_Homo sapiens_hsa05144 | 1.16657433 |
| 37 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.14618751 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.12706545 |
| 39 | Asthma_Homo sapiens_hsa05310 | 1.10402869 |
| 40 | Shigellosis_Homo sapiens_hsa05131 | 1.07831634 |
| 41 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.05463270 |
| 42 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.03771049 |
| 43 | Legionellosis_Homo sapiens_hsa05134 | 0.98965257 |
| 44 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.98351692 |
| 45 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.97568895 |
| 46 | Platelet activation_Homo sapiens_hsa04611 | 0.96574625 |
| 47 | Hepatitis C_Homo sapiens_hsa05160 | 0.93756316 |
| 48 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.92812057 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.89798937 |
| 50 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.85718331 |
| 51 | Apoptosis_Homo sapiens_hsa04210 | 0.85664908 |
| 52 | HTLV-I infection_Homo sapiens_hsa05166 | 0.84387470 |
| 53 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.83240829 |
| 54 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.82707051 |
| 55 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.82648246 |
| 56 | Pertussis_Homo sapiens_hsa05133 | 0.80694209 |
| 57 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.78983805 |
| 58 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.77249505 |
| 59 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.76846902 |
| 60 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.76682780 |
| 61 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.68196225 |
| 62 | Phagosome_Homo sapiens_hsa04145 | 0.67420385 |
| 63 | Other glycan degradation_Homo sapiens_hsa00511 | 0.65756168 |
| 64 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.63303804 |
| 65 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.63163350 |
| 66 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.62977834 |
| 67 | Colorectal cancer_Homo sapiens_hsa05210 | 0.61345963 |
| 68 | Endometrial cancer_Homo sapiens_hsa05213 | 0.58580354 |
| 69 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.57068593 |
| 70 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.55602866 |
| 71 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.54649807 |
| 72 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.53567470 |
| 73 | Endocytosis_Homo sapiens_hsa04144 | 0.51391760 |
| 74 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.51113732 |
| 75 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.48760764 |
| 76 | Salmonella infection_Homo sapiens_hsa05132 | 0.47839243 |
| 77 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.46569541 |
| 78 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41741010 |
| 79 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41544910 |
| 80 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39455915 |
| 81 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38023511 |
| 82 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.36037744 |
| 83 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.35766730 |
| 84 | Insulin resistance_Homo sapiens_hsa04931 | 0.33578492 |
| 85 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.33138930 |
| 86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.29885509 |
| 87 | ABC transporters_Homo sapiens_hsa02010 | 0.28898292 |
| 88 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.28170004 |
| 89 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.27650348 |
| 90 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27475981 |
| 91 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.26114964 |
| 92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25425999 |
| 93 | Prostate cancer_Homo sapiens_hsa05215 | 0.25243820 |
| 94 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.24507882 |
| 95 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.21625052 |
| 96 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.21026038 |
| 97 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.20804709 |
| 98 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.19859993 |
| 99 | Long-term depression_Homo sapiens_hsa04730 | 0.18708500 |
| 100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.17710018 |

